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Connection

Alexander Horswill to Staphylococcal Infections

This is a "connection" page, showing publications Alexander Horswill has written about Staphylococcal Infections.

 
Connection Strength
  
 
 
22.819
  
  1. Bhattacharya M, Scherr TD, Lister J, Kielian T, Horswill AR. Extracellular adherence proteins reduce matrix porosity and enhance Staphylococcus aureus biofilm survival during prosthetic joint infection. Infect Immun. 2025 04 08; 93(4):e0008625.
    View in: PubMed
    Score: 0.665
  2. Lyon LM, Marroquin SM, Thorstenson JC, Joyce LR, Fuentes EJ, Doran KS, Horswill AR. Genome-wide mutagenesis identifies factors involved in MRSA vaginal colonization. Cell Rep. 2025 Mar 25; 44(3):115421.
    View in: PubMed
    Score: 0.664
  3. Crosby HA, Keim K, Kwiecinski JM, Langouët-Astrié CJ, Oshima K, LaRivière WB, Schmidt EP, Horswill AR. Host-derived protease promotes aggregation of Staphylococcus aureus by cleaving the surface protein SasG. mBio. 2024 Apr 10; 15(4):e0348323.
    View in: PubMed
    Score: 0.621
  4. Bhattacharya M, Horswill AR. The role of human extracellular matrix proteins in defining Staphylococcus aureus biofilm infections. FEMS Microbiol Rev. 2024 Jan 12; 48(1).
    View in: PubMed
    Score: 0.613
  5. Schilcher K, Severn MM, Jenul C, Avina YC, Keogh RA, Horswill AR. The Staphylococcus aureus CamS lipoprotein is a repressor of toxin production that shapes host-pathogen interaction. PLoS Biol. 2024 Jan; 22(1):e3002451.
    View in: PubMed
    Score: 0.612
  6. Keim KC, Horswill AR. Staphylococcus aureus. Trends Microbiol. 2023 12; 31(12):1300-1301.
    View in: PubMed
    Score: 0.593
  7. Jenul C, Keim KC, Jens JN, Zeiler MJ, Schilcher K, Schurr MJ, Melander C, Phelan VV, Horswill AR. Pyochelin biotransformation by Staphylococcus aureus shapes bacterial competition with Pseudomonas aeruginosa in polymicrobial infections. Cell Rep. 2023 06 27; 42(6):112540.
    View in: PubMed
    Score: 0.586
  8. Lyon LM, Doran KS, Horswill AR. Staphylococcus aureus Fibronectin-Binding Proteins Contribute to Colonization of the Female Reproductive Tract. Infect Immun. 2023 01 24; 91(1):e0046022.
    View in: PubMed
    Score: 0.568
  9. Mills KB, Roy P, Kwiecinski JM, Fey PD, Horswill AR. Staphylococcal Corneocyte Adhesion: Assay Optimization and Roles of Aap and SasG Adhesins in the Establishment of Healthy Skin Colonization. Microbiol Spectr. 2022 12 21; 10(6):e0246922.
    View in: PubMed
    Score: 0.562
  10. Severn MM, Horswill AR. Staphylococcus epidermidis and its dual lifestyle in skin health and infection. Nat Rev Microbiol. 2023 02; 21(2):97-111.
    View in: PubMed
    Score: 0.557
  11. Severn MM, Cho YK, Manzer HS, Bunch ZL, Shahbandi A, Todd DA, Cech NB, Horswill AR. The Commensal Staphylococcus warneri Makes Peptide Inhibitors of MRSA Quorum Sensing that Protect Skin from Atopic or Necrotic Damage. J Invest Dermatol. 2022 12; 142(12):3349-3352.e5.
    View in: PubMed
    Score: 0.551
  12. Kwiecinski JM, Jelani DA, Fuentes EJ, Horswill AR. Therapeutic Inhibition of Staphylococcus aureus ArlRS Two-Component Regulatory System Blocks Virulence. Antimicrob Agents Chemother. 2022 07 19; 66(7):e0018722.
    View in: PubMed
    Score: 0.550
  13. Costa FG, Horswill AR. Overcoming pH defenses on the skin to establish infections. PLoS Pathog. 2022 05; 18(5):e1010512.
    View in: PubMed
    Score: 0.547
  14. Severn MM, Williams MR, Shahbandi A, Bunch ZL, Lyon LM, Nguyen A, Zaramela LS, Todd DA, Zengler K, Cech NB, Gallo RL, Horswill AR. The Ubiquitous Human Skin Commensal Staphylococcus hominis Protects against Opportunistic Pathogens. mBio. 2022 06 28; 13(3):e0093022.
    View in: PubMed
    Score: 0.547
  15. Kwiecinski JM, Kratofil RM, Parlet CP, Surewaard BGJ, Kubes P, Horswill AR. Staphylococcus aureus uses the ArlRS and MgrA cascade to regulate immune evasion during skin infection. Cell Rep. 2021 07 27; 36(4):109462.
    View in: PubMed
    Score: 0.516
  16. Kavanaugh JS, Leidal KG, Nauseef WM, Horswill AR. Cathepsin G Degrades Staphylococcus aureus Biofilms. J Infect Dis. 2021 06 04; 223(11):1865-1869.
    View in: PubMed
    Score: 0.511
  17. Schilcher K, Horswill AR. Staphylococcal Biofilm Development: Structure, Regulation, and Treatment Strategies. Microbiol Mol Biol Rev. 2020 08 19; 84(3).
    View in: PubMed
    Score: 0.483
  18. Brown MM, Kwiecinski JM, Cruz LM, Shahbandi A, Todd DA, Cech NB, Horswill AR. Novel Peptide from Commensal Staphylococcus simulans Blocks Methicillin-Resistant Staphylococcus aureus Quorum Sensing and Protects Host Skin from Damage. Antimicrob Agents Chemother. 2020 05 21; 64(6).
    View in: PubMed
    Score: 0.476
  19. Kwiecinski JM, Horswill AR. Staphylococcus aureus bloodstream infections: pathogenesis and regulatory mechanisms. Curr Opin Microbiol. 2020 02; 53:51-60.
    View in: PubMed
    Score: 0.470
  20. Horswill AR, Gordon CP. Structure-Activity Relationship Studies of Small Molecule Modulators of the Staphylococcal Accessory Gene Regulator. J Med Chem. 2020 03 26; 63(6):2705-2730.
    View in: PubMed
    Score: 0.459
  21. Kwiecinski JM, Crosby HA, Valotteau C, Hippensteel JA, Nayak MK, Chauhan AK, Schmidt EP, Dufrêne YF, Horswill AR. Staphylococcus aureus adhesion in endovascular infections is controlled by the ArlRS-MgrA signaling cascade. PLoS Pathog. 2019 05; 15(5):e1007800.
    View in: PubMed
    Score: 0.444
  22. Jenul C, Horswill AR. Regulation of Staphylococcus aureus Virulence. Microbiol Spectr. 2019 04 05; 7(2).
    View in: PubMed
    Score: 0.440
  23. Parlet CP, Kavanaugh JS, Crosby HA, Raja HA, El-Elimat T, Todd DA, Pearce CJ, Cech NB, Oberlies NH, Horswill AR. Apicidin Attenuates MRSA Virulence through Quorum-Sensing Inhibition and Enhanced Host Defense. Cell Rep. 2019 04 02; 27(1):187-198.e6.
    View in: PubMed
    Score: 0.440
  24. Loftus RW, Dexter F, Robinson ADM, Horswill AR. Desiccation tolerance is associated with Staphylococcus aureus hypertransmissibility, resistance and infection development in the operating room. J Hosp Infect. 2018 Nov; 100(3):299-308.
    View in: PubMed
    Score: 0.417
  25. Paharik AE, Parlet CP, Chung N, Todd DA, Rodriguez EI, Van Dyke MJ, Cech NB, Horswill AR. Coagulase-Negative Staphylococcal Strain Prevents Staphylococcus aureus Colonization and Skin Infection by Blocking Quorum Sensing. Cell Host Microbe. 2017 Dec 13; 22(6):746-756.e5.
    View in: PubMed
    Score: 0.401
  26. Gordon CP, Olson SD, Lister JL, Kavanaugh JS, Horswill AR. Truncated Autoinducing Peptides as Antagonists of Staphylococcus lugdunensis Quorum Sensing. J Med Chem. 2016 10 13; 59(19):8879-8888.
    View in: PubMed
    Score: 0.369
  27. Crosby HA, Kwiecinski J, Horswill AR. Staphylococcus aureus Aggregation and Coagulation Mechanisms, and Their Function in Host-Pathogen Interactions. Adv Appl Microbiol. 2016; 96:1-41.
    View in: PubMed
    Score: 0.366
  28. Ibberson CB, Parlet CP, Kwiecinski J, Crosby HA, Meyerholz DK, Horswill AR. Hyaluronan Modulation Impacts Staphylococcus aureus Biofilm Infection. Infect Immun. 2016 06; 84(6):1917-1929.
    View in: PubMed
    Score: 0.361
  29. Crosby HA, Schlievert PM, Merriman JA, King JM, Salgado-Pabón W, Horswill AR. The Staphylococcus aureus Global Regulator MgrA Modulates Clumping and Virulence by Controlling Surface Protein Expression. PLoS Pathog. 2016 05; 12(5):e1005604.
    View in: PubMed
    Score: 0.359
  30. Kavanaugh JS, Horswill AR. Impact of Environmental Cues on Staphylococcal Quorum Sensing and Biofilm Development. J Biol Chem. 2016 Jun 10; 291(24):12556-12564.
    View in: PubMed
    Score: 0.359
  31. Kiedrowski MR, Paharik AE, Ackermann LW, Shelton AU, Singh SB, Starner TD, Horswill AR. Development of an in vitro colonization model to investigate Staphylococcus aureus interactions with airway epithelia. Cell Microbiol. 2016 May; 18(5):720-32.
    View in: PubMed
    Score: 0.352
  32. Mootz JM, Benson MA, Heim CE, Crosby HA, Kavanaugh JS, Dunman PM, Kielian T, Torres VJ, Horswill AR. Rot is a key regulator of Staphylococcus aureus biofilm formation. Mol Microbiol. 2015 Apr; 96(2):388-404.
    View in: PubMed
    Score: 0.331
  33. Lister JL, Horswill AR. Staphylococcus aureus biofilms: recent developments in biofilm dispersal. Front Cell Infect Microbiol. 2014; 4:178.
    View in: PubMed
    Score: 0.327
  34. Olson ME, Todd DA, Schaeffer CR, Paharik AE, Van Dyke MJ, Büttner H, Dunman PM, Rohde H, Cech NB, Fey PD, Horswill AR. Staphylococcus epidermidis agr quorum-sensing system: signal identification, cross talk, and importance in colonization. J Bacteriol. 2014 Oct; 196(19):3482-93.
    View in: PubMed
    Score: 0.318
  35. Cech NB, Horswill AR. Small-molecule quorum quenchers to prevent Staphylococcus aureus infection. Future Microbiol. 2013 Dec; 8(12):1511-4.
    View in: PubMed
    Score: 0.304
  36. Mootz JM, Malone CL, Shaw LN, Horswill AR. Staphopains modulate Staphylococcus aureus biofilm integrity. Infect Immun. 2013 Sep; 81(9):3227-38.
    View in: PubMed
    Score: 0.295
  37. Olson ME, Horswill AR. Staphylococcus aureus osteomyelitis: bad to the bone. Cell Host Microbe. 2013 Jun 12; 13(6):629-31.
    View in: PubMed
    Score: 0.294
  38. Kiedrowski MR, Horswill AR. New approaches for treating staphylococcal biofilm infections. Ann N Y Acad Sci. 2011 Dec; 1241:104-21.
    View in: PubMed
    Score: 0.265
  39. Boles BR, Horswill AR. Staphylococcal biofilm disassembly. Trends Microbiol. 2011 Sep; 19(9):449-55.
    View in: PubMed
    Score: 0.258
  40. Lauderdale KJ, Malone CL, Boles BR, Morcuende J, Horswill AR. Biofilm dispersal of community-associated methicillin-resistant Staphylococcus aureus on orthopedic implant material. J Orthop Res. 2010 Jan; 28(1):55-61.
    View in: PubMed
    Score: 0.232
  41. Horswill AR, Nauseef WM. Host interception of bacterial communication signals. Cell Host Microbe. 2008 Dec 11; 4(6):507-9.
    View in: PubMed
    Score: 0.215
  42. Tamkin E, Lorenz BP, McCarty A, Fulte S, Eisenmesser E, Horswill AR, Clark SE. Airway Corynebacterium interfere with Streptococcus pneumoniae and Staphylococcus aureus infection and express secreted factors selectively targeting each pathogen. Infect Immun. 2025 02 18; 93(2):e0044524.
    View in: PubMed
    Score: 0.163
  43. Costa FG, Mills KB, Crosby HA, Horswill AR. The Staphylococcus aureus regulatory program in a human skin-like environment. mBio. 2024 May 08; 15(5):e0045324.
    View in: PubMed
    Score: 0.155
  44. Gallo RL, Horswill AR. Staphylococcus aureus: The Bug Behind the Itch in Atopic Dermatitis. J Invest Dermatol. 2024 05; 144(5):950-953.
    View in: PubMed
    Score: 0.155
  45. Deng L, Costa F, Blake KJ, Choi S, Chandrabalan A, Yousuf MS, Shiers S, Dubreuil D, Vega-Mendoza D, Rolland C, Deraison C, Voisin T, Bagood MD, Wesemann L, Frey AM, Palumbo JS, Wainger BJ, Gallo RL, Leyva-Castillo JM, Vergnolle N, Price TJ, Ramachandran R, Horswill AR, Chiu IM. S. aureus drives itch and scratch-induced skin damage through a V8 protease-PAR1 axis. Cell. 2023 11 22; 186(24):5375-5393.e25.
    View in: PubMed
    Score: 0.152
  46. Williams MR, Bagood MD, Enroth TJ, Bunch ZL, Jiang N, Liu E, Almoughrabie S, Khalil S, Li F, Brinton S, Cech NB, Horswill AR, Gallo RL. Staphylococcus epidermidis activates keratinocyte cytokine expression and promotes skin inflammation through the production of phenol-soluble modulins. Cell Rep. 2023 09 26; 42(9):113024.
    View in: PubMed
    Score: 0.149
  47. Weig AW, O'Conner PM, Kwiecinski JM, Marciano OM, Nunag A, Gutierrez AT, Melander RJ, Horswill AR, Melander C. A structure activity relationship study of 3,4'-dimethoxyflavone for ArlRS inhibition in Staphylococcus aureus. Org Biomol Chem. 2023 04 26; 21(16):3373-3380.
    View in: PubMed
    Score: 0.146
  48. Staats A, Burback PW, Casillas-Ituarte NN, Li D, Hostetler MR, Sullivan A, Horswill AR, Lower SK, Stoodley P. In Vitro Staphylococcal Aggregate Morphology and Protection from Antibiotics Are Dependent on Distinct Mechanisms Arising from Postsurgical Joint Components and Fluid Motion. J Bacteriol. 2023 04 25; 205(4):e0045122.
    View in: PubMed
    Score: 0.145
  49. Hinman KD, Laforce-Nesbitt SS, Cohen JT, Mundy M, Bliss JM, Horswill AR, Lefort CT. Bi-fluorescent Staphylococcus aureus infection enables single-cell analysis of intracellular killing in vivo. Front Immunol. 2023; 14:1089111.
    View in: PubMed
    Score: 0.143
  50. Lee J, Carda-Diéguez M, ?iemyte M, Vreugde S, Cooksley C, Crosby HA, Horswill AR, Mira A, Zilm PS, Kidd SP. Functional mgrA Influences Genetic Changes within a Staphylococcus aureus Cell Population over Time. J Bacteriol. 2022 Oct 18; 204(10):e0013822.
    View in: PubMed
    Score: 0.140
  51. Haynes AS, Prinzi A, Silveira LJ, Parker SK, Lampe JN, Kavanaugh JS, Horswill AR, Fish D. Cefadroxil Comparable to Cephalexin: Minimum Inhibitory Concentrations among Methicillin-Susceptible Staphylococcus aureus Isolates from Pediatric Musculoskeletal Infections. Microbiol Spectr. 2022 08 31; 10(4):e0103922.
    View in: PubMed
    Score: 0.137
  52. Staats A, Burback PW, Schwieters A, Li D, Sullivan A, Horswill AR, Stoodley P. Rapid Aggregation of Staphylococcus aureus in Synovial Fluid Is Influenced by Synovial Fluid Concentration, Viscosity, and Fluid Dynamics, with Evidence of Polymer Bridging. mBio. 2022 04 26; 13(2):e0023622.
    View in: PubMed
    Score: 0.135
  53. Leyva-Castillo JM, Das M, Kane J, Strakosha M, Singh S, Wong DSH, Horswill AR, Karasuyama H, Brombacher F, Miller LS, Geha RS. Basophil-derived IL-4 promotes cutaneous Staphylococcus aureus infection. JCI Insight. 2021 11 08; 6(21).
    View in: PubMed
    Score: 0.132
  54. Hook JS, Patel PA, O'Malley A, Xie L, Kavanaugh JS, Horswill AR, Moreland JG. Lipoproteins from Staphylococcus aureus Drive Neutrophil Extracellular Trap Formation in a TLR2/1- and PAD-Dependent Manner. J Immunol. 2021 08 01; 207(3):966-973.
    View in: PubMed
    Score: 0.129
  55. Nakamura K, Williams MR, Kwiecinski JM, Horswill AR, Gallo RL. Staphylococcus aureus Enters Hair Follicles Using Triacylglycerol Lipases Preserved through the Genus Staphylococcus. J Invest Dermatol. 2021 08; 141(8):2094-2097.
    View in: PubMed
    Score: 0.126
  56. Bispo M, Anaya-Sanchez A, Suhani S, Raineri EJM, López-Álvarez M, Heuker M, Szymanski W, Romero Pastrana F, Buist G, Horswill AR, Francis KP, van Dam GM, van Oosten M, van Dijl JM. Fighting Staphylococcus aureus infections with light and photoimmunoconjugates. JCI Insight. 2020 11 19; 5(22).
    View in: PubMed
    Score: 0.123
  57. Gupta TT, Gupta NK, Pestrak MJ, Dusane DH, Harro JM, Horswill AR, Stoodley P. Staphylococcus aureus Aggregates on Orthopedic Materials under Varying Levels of Shear Stress. Appl Environ Microbiol. 2020 09 17; 86(19).
    View in: PubMed
    Score: 0.122
  58. Sirobhushanam S, Parsa N, Reed TJ, Berthier CC, Sarkar MK, Hile GA, Tsoi LC, Banfield J, Dobry C, Horswill AR, Gudjonsson JE, Kahlenberg JM. Staphylococcus aureus Colonization Is Increased on Lupus Skin Lesions and Is Promoted by IFN-Mediated Barrier Disruption. J Invest Dermatol. 2020 05; 140(5):1066-1074.e4.
    View in: PubMed
    Score: 0.116
  59. Miller RJ, Crosby HA, Schilcher K, Wang Y, Ortines RV, Mazhar M, Dikeman DA, Pinsker BL, Brown ID, Joyce DP, Zhang J, Archer NK, Liu H, Alphonse MP, Czupryna J, Anderson WR, Bernthal NM, Fortuno-Miranda L, Bulte JWM, Francis KP, Horswill AR, Miller LS. Development of a Staphylococcus aureus reporter strain with click beetle red luciferase for enhanced in vivo imaging of experimental bacteremia and mixed infections. Sci Rep. 2019 11 13; 9(1):16663.
    View in: PubMed
    Score: 0.115
  60. Grundstad ML, Parlet CP, Kwiecinski JM, Kavanaugh JS, Crosby HA, Cho YS, Heilmann K, Diekema DJ, Horswill AR. Quorum Sensing, Virulence, and Antibiotic Resistance of USA100 Methicillin-Resistant Staphylococcus aureus Isolates. mSphere. 2019 08 14; 4(4).
    View in: PubMed
    Score: 0.113
  61. Borbón TY, Scorza BM, Clay GM, Lima Nobre de Queiroz F, Sariol AJ, Bowen JL, Chen Y, Zhanbolat B, Parlet CP, Valadares DG, Cassel SL, Nauseef WM, Horswill AR, Sutterwala FS, Wilson ME. Coinfection with Leishmania major and Staphylococcus aureus enhances the pathologic responses to both microbes through a pathway involving IL-17A. PLoS Negl Trop Dis. 2019 05; 13(5):e0007247.
    View in: PubMed
    Score: 0.111
  62. Kwiecinski JM, Jacobsson G, Horswill AR, Josefsson E, Jin T. Biofilm formation by Staphylococcus aureus clinical isolates correlates with the infection type. Infect Dis (Lond). 2019 06; 51(6):446-451.
    View in: PubMed
    Score: 0.110
  63. Trivedi U, Madsen JS, Everett J, Fell C, Russel J, Haaber J, Crosby HA, Horswill AR, Burmølle M, Rumbaugh KP, Sørensen SJ. Staphylococcus aureus coagulases are exploitable yet stable public goods in clinically relevant conditions. Proc Natl Acad Sci U S A. 2018 12 11; 115(50):E11771-E11779.
    View in: PubMed
    Score: 0.107
  64. Paharik AE, Horswill AR. The Staphylococcal Biofilm: Adhesins, Regulation, and Host Response. Microbiol Spectr. 2016 04; 4(2).
    View in: PubMed
    Score: 0.089
  65. Daly SM, Elmore BO, Kavanaugh JS, Triplett KD, Figueroa M, Raja HA, El-Elimat T, Crosby HA, Femling JK, Cech NB, Horswill AR, Oberlies NH, Hall PR. ?-Hydroxyemodin limits staphylococcus aureus quorum sensing-mediated pathogenesis and inflammation. Antimicrob Agents Chemother. 2015 Apr; 59(4):2223-35.
    View in: PubMed
    Score: 0.082
  66. Schaeffer CR, Woods KM, Longo GM, Kiedrowski MR, Paharik AE, Büttner H, Christner M, Boissy RJ, Horswill AR, Rohde H, Fey PD. Accumulation-associated protein enhances Staphylococcus epidermidis biofilm formation under dynamic conditions and is required for infection in a rat catheter model. Infect Immun. 2015 Jan; 83(1):214-26.
    View in: PubMed
    Score: 0.081
  67. Kiedrowski MR, Crosby HA, Hernandez FJ, Malone CL, McNamara JO, Horswill AR. Staphylococcus aureus Nuc2 is a functional, surface-attached extracellular nuclease. PLoS One. 2014; 9(4):e95574.
    View in: PubMed
    Score: 0.078
  68. Hernandez FJ, Huang L, Olson ME, Powers KM, Hernandez LI, Meyerholz DK, Thedens DR, Behlke MA, Horswill AR, McNamara JO. Noninvasive imaging of Staphylococcus aureus infections with a nuclease-activated probe. Nat Med. 2014 Mar; 20(3):301-6.
    View in: PubMed
    Score: 0.077
  69. White MJ, Boyd JM, Horswill AR, Nauseef WM. Phosphatidylinositol-specific phospholipase C contributes to survival of Staphylococcus aureus USA300 in human blood and neutrophils. Infect Immun. 2014 Apr; 82(4):1559-71.
    View in: PubMed
    Score: 0.077
  70. Walker JN, Crosby HA, Spaulding AR, Salgado-Pabón W, Malone CL, Rosenthal CB, Schlievert PM, Boyd JM, Horswill AR. The Staphylococcus aureus ArlRS two-component system is a novel regulator of agglutination and pathogenesis. PLoS Pathog. 2013; 9(12):e1003819.
    View in: PubMed
    Score: 0.076
  71. Pang YY, Schwartz J, Bloomberg S, Boyd JM, Horswill AR, Nauseef WM. Methionine sulfoxide reductases protect against oxidative stress in Staphylococcus aureus encountering exogenous oxidants and human neutrophils. J Innate Immun. 2014; 6(3):353-64.
    View in: PubMed
    Score: 0.076
  72. Salgado-Pabón W, Breshears L, Spaulding AR, Merriman JA, Stach CS, Horswill AR, Peterson ML, Schlievert PM. Superantigens are critical for Staphylococcus aureus Infective endocarditis, sepsis, and acute kidney injury. mBio. 2013 Aug 20; 4(4).
    View in: PubMed
    Score: 0.074
  73. Zurek OW, Nygaard TK, Watkins RL, Pallister KB, Torres VJ, Horswill AR, Voyich JM. The role of innate immunity in promoting SaeR/S-mediated virulence in Staphylococcus aureus. J Innate Immun. 2014; 6(1):21-30.
    View in: PubMed
    Score: 0.074
  74. Hall PR, Elmore BO, Spang CH, Alexander SM, Manifold-Wheeler BC, Castleman MJ, Daly SM, Peterson MM, Sully EK, Femling JK, Otto M, Horswill AR, Timmins GS, Gresham HD. Nox2 modification of LDL is essential for optimal apolipoprotein B-mediated control of agr type III Staphylococcus aureus quorum-sensing. PLoS Pathog. 2013 Feb; 9(2):e1003166.
    View in: PubMed
    Score: 0.072
  75. Kaplan JB, Izano EA, Gopal P, Karwacki MT, Kim S, Bose JL, Bayles KW, Horswill AR. Low levels of ß-lactam antibiotics induce extracellular DNA release and biofilm formation in Staphylococcus aureus. mBio. 2012; 3(4):e00198-12.
    View in: PubMed
    Score: 0.069
  76. Lin YC, Anderson MJ, Kohler PL, Strandberg KL, Olson ME, Horswill AR, Schlievert PM, Peterson ML. Proinflammatory exoprotein characterization of toxic shock syndrome Staphylococcus aureus. Biochemistry. 2011 Aug 23; 50(33):7157-67.
    View in: PubMed
    Score: 0.064
  77. Thurlow LR, Hanke ML, Fritz T, Angle A, Aldrich A, Williams SH, Engebretsen IL, Bayles KW, Horswill AR, Kielian T. Staphylococcus aureus biofilms prevent macrophage phagocytosis and attenuate inflammation in vivo. J Immunol. 2011 Jun 01; 186(11):6585-96.
    View in: PubMed
    Score: 0.063
  78. Laarman AJ, Ruyken M, Malone CL, van Strijp JA, Horswill AR, Rooijakkers SH. Staphylococcus aureus metalloprotease aureolysin cleaves complement C3 to mediate immune evasion. J Immunol. 2011 Jun 01; 186(11):6445-53.
    View in: PubMed
    Score: 0.063
  79. Pang YY, Schwartz J, Thoendel M, Ackermann LW, Horswill AR, Nauseef WM. agr-Dependent interactions of Staphylococcus aureus USA300 with human polymorphonuclear neutrophils. J Innate Immun. 2010; 2(6):546-59.
    View in: PubMed
    Score: 0.061
  80. Berends ET, Horswill AR, Haste NM, Monestier M, Nizet V, von Köckritz-Blickwede M. Nuclease expression by Staphylococcus aureus facilitates escape from neutrophil extracellular traps. J Innate Immun. 2010; 2(6):576-86.
    View in: PubMed
    Score: 0.061
  81. Teghanemt A, Schilcher K, Kavanaugh JS, Horswill AR, Nauseef WM. Mutation in Staphylococcus aureus that supports gain of function in susceptibility both to hypochlorous acid and to human neutrophils. J Leukoc Biol. 2025 Jul 09; 117(7).
    View in: PubMed
    Score: 0.042
  82. de Vor L, van Dijk B, van Kessel K, Kavanaugh JS, de Haas C, Aerts PC, Viveen MC, Boel EC, Fluit AC, Kwiecinski JM, Krijger GC, Ramakers RM, Beekman FJ, Dadachova E, Lam MG, Vogely HC, van der Wal BC, van Strijp JA, Horswill AR, Weinans H, Rooijakkers SH. Human monoclonal antibodies against Staphylococcus aureus surface antigens recognize in vitro and in vivo biofilm. Elife. 2022 01 06; 11.
    View in: PubMed
    Score: 0.033
  83. Roy P, Horswill AR, Fey PD. Glycan-Dependent Corneocyte Adherence of Staphylococcus epidermidis Mediated by the Lectin Subdomain of Aap. mBio. 2021 08 31; 12(4):e0290820.
    View in: PubMed
    Score: 0.032
  84. West KHJ, Shen W, Eisenbraun EL, Yang T, Vasquez JK, Horswill AR, Blackwell HE. Non-Native Peptides Capable of Pan-Activating the agr Quorum Sensing System across Multiple Specificity Groups of Staphylococcus epidermidis. ACS Chem Biol. 2021 06 18; 16(6):1070-1078.
    View in: PubMed
    Score: 0.032
  85. Urbano R, Karlinsey JE, Libby SJ, Doulias PT, Ischiropoulos H, Warheit-Niemi HI, Liggitt DH, Horswill AR, Fang FC. Host Nitric Oxide Disrupts Microbial Cell-to-Cell Communication to Inhibit Staphylococcal Virulence. Cell Host Microbe. 2018 05 09; 23(5):594-606.e7.
    View in: PubMed
    Score: 0.026
  86. Todd DA, Parlet CP, Crosby HA, Malone CL, Heilmann KP, Horswill AR, Cech NB. Signal Biosynthesis Inhibition with Ambuic Acid as a Strategy To Target Antibiotic-Resistant Infections. Antimicrob Agents Chemother. 2017 08; 61(8).
    View in: PubMed
    Score: 0.024
  87. Todd DA, Zich DB, Ettefagh KA, Kavanaugh JS, Horswill AR, Cech NB. Hybrid Quadrupole-Orbitrap mass spectrometry for quantitative measurement of quorum sensing inhibition. J Microbiol Methods. 2016 08; 127:89-94.
    View in: PubMed
    Score: 0.023
  88. Herrera A, Vu BG, Stach CS, Merriman JA, Horswill AR, Salgado-Pabón W, Schlievert PM. Staphylococcus aureus ß-Toxin Mutants Are Defective in Biofilm Ligase and Sphingomyelinase Activity, and Causation of Infective Endocarditis and Sepsis. Biochemistry. 2016 05 03; 55(17):2510-7.
    View in: PubMed
    Score: 0.022
  89. Scherr TD, Hanke ML, Huang O, James DB, Horswill AR, Bayles KW, Fey PD, Torres VJ, Kielian T. Staphylococcus aureus Biofilms Induce Macrophage Dysfunction Through Leukocidin AB and Alpha-Toxin. mBio. 2015 Aug 25; 6(4).
    View in: PubMed
    Score: 0.021
  90. Chiu IM, Heesters BA, Ghasemlou N, Von Hehn CA, Zhao F, Tran J, Wainger B, Strominger A, Muralidharan S, Horswill AR, Bubeck Wardenburg J, Hwang SW, Carroll MC, Woolf CJ. Bacteria activate sensory neurons that modulate pain and inflammation. Nature. 2013 Sep 05; 501(7465):52-7.
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    Score: 0.019
  91. Spaulding AR, Salgado-Pabón W, Kohler PL, Horswill AR, Leung DY, Schlievert PM. Staphylococcal and streptococcal superantigen exotoxins. Clin Microbiol Rev. 2013 Jul; 26(3):422-47.
    View in: PubMed
    Score: 0.018
  92. Abdelhady W, Bayer AS, Seidl K, Nast CC, Kiedrowski MR, Horswill AR, Yeaman MR, Xiong YQ. Reduced vancomycin susceptibility in an in vitro catheter-related biofilm model correlates with poor therapeutic outcomes in experimental endocarditis due to methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother. 2013 Mar; 57(3):1447-54.
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    Score: 0.018
  93. Kolar SL, Ibarra JA, Rivera FE, Mootz JM, Davenport JE, Stevens SM, Horswill AR, Shaw LN. Extracellular proteases are key mediators of Staphylococcus aureus virulence via the global modulation of virulence-determinant stability. Microbiologyopen. 2013 Feb; 2(1):18-34.
    View in: PubMed
    Score: 0.018
  94. Zielinska AK, Beenken KE, Mrak LN, Spencer HJ, Post GR, Skinner RA, Tackett AJ, Horswill AR, Smeltzer MS. sarA-mediated repression of protease production plays a key role in the pathogenesis of Staphylococcus aureus USA300 isolates. Mol Microbiol. 2012 Dec; 86(5):1183-96.
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    Score: 0.018
  95. Benson MA, Lilo S, Wasserman GA, Thoendel M, Smith A, Horswill AR, Fraser J, Novick RP, Shopsin B, Torres VJ. Staphylococcus aureus regulates the expression and production of the staphylococcal superantigen-like secreted proteins in a Rot-dependent manner. Mol Microbiol. 2011 Aug; 81(3):659-75.
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    Score: 0.016
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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