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Connection

Alexander Horswill to Staphylococcus aureus

This is a "connection" page, showing publications Alexander Horswill has written about Staphylococcus aureus.

 
Connection Strength
  
 
 
25.624
  
  1. Bhattacharya M, Scherr TD, Lister J, Kielian T, Horswill AR. Extracellular adherence proteins reduce matrix porosity and enhance Staphylococcus aureus biofilm survival during prosthetic joint infection. Infect Immun. 2025 04 08; 93(4):e0008625.
    View in: PubMed
    Score: 0.689
  2. Enroth TJ, Severn MM, Costa FG, Bovee AR, Wilkening RV, Nguyen DT, Langouët-Astrié C, Horswill AR. Global changes in Staphylococcus aureus virulence and metabolism during colonization of healthy skin. Infect Immun. 2025 04 08; 93(4):e0002825.
    View in: PubMed
    Score: 0.689
  3. Mills KB, Maciag JJ, Wang C, Crawford JA, Enroth TJ, Keim KC, Dufrêne YF, Robinson DA, Fey PD, Herr AB, Horswill AR. Staphylococcus aureus skin colonization is mediated by SasG lectin variation. Cell Rep. 2024 04 23; 43(4):114022.
    View in: PubMed
    Score: 0.644
  4. Gallo RL, Horswill AR. Staphylococcus aureus: The Bug Behind the Itch in Atopic Dermatitis. J Invest Dermatol. 2024 05; 144(5):950-953.
    View in: PubMed
    Score: 0.640
  5. Schilcher K, Severn MM, Jenul C, Avina YC, Keogh RA, Horswill AR. The Staphylococcus aureus CamS lipoprotein is a repressor of toxin production that shapes host-pathogen interaction. PLoS Biol. 2024 Jan; 22(1):e3002451.
    View in: PubMed
    Score: 0.633
  6. Keim KC, Horswill AR. Staphylococcus aureus. Trends Microbiol. 2023 12; 31(12):1300-1301.
    View in: PubMed
    Score: 0.613
  7. Costa FG, Horswill AR. Overcoming pH defenses on the skin to establish infections. PLoS Pathog. 2022 05; 18(5):e1010512.
    View in: PubMed
    Score: 0.566
  8. Severn MM, Williams MR, Shahbandi A, Bunch ZL, Lyon LM, Nguyen A, Zaramela LS, Todd DA, Zengler K, Cech NB, Gallo RL, Horswill AR. The Ubiquitous Human Skin Commensal Staphylococcus hominis Protects against Opportunistic Pathogens. mBio. 2022 06 28; 13(3):e0093022.
    View in: PubMed
    Score: 0.566
  9. Kwiecinski JM, Kratofil RM, Parlet CP, Surewaard BGJ, Kubes P, Horswill AR. Staphylococcus aureus uses the ArlRS and MgrA cascade to regulate immune evasion during skin infection. Cell Rep. 2021 07 27; 36(4):109462.
    View in: PubMed
    Score: 0.535
  10. Kavanaugh JS, Leidal KG, Nauseef WM, Horswill AR. Cathepsin G Degrades Staphylococcus aureus Biofilms. J Infect Dis. 2021 06 04; 223(11):1865-1869.
    View in: PubMed
    Score: 0.529
  11. Crosby HA, Kwiecinski JM, Horswill AR. In Vitro Assay for Quantifying Clumping of Staphylococcus aureus. Methods Mol Biol. 2021; 2341:31-36.
    View in: PubMed
    Score: 0.514
  12. Schilcher K, Horswill AR. Staphylococcal Biofilm Development: Structure, Regulation, and Treatment Strategies. Microbiol Mol Biol Rev. 2020 08 19; 84(3).
    View in: PubMed
    Score: 0.500
  13. Schilcher K, Caesar LK, Cech NB, Horswill AR. Processing, Export, and Identification of Novel Linear Peptides from Staphylococcus aureus. mBio. 2020 04 14; 11(2).
    View in: PubMed
    Score: 0.489
  14. Kwiecinski JM, Horswill AR. Staphylococcus aureus bloodstream infections: pathogenesis and regulatory mechanisms. Curr Opin Microbiol. 2020 02; 53:51-60.
    View in: PubMed
    Score: 0.486
  15. Horswill AR, Gordon CP. Structure-Activity Relationship Studies of Small Molecule Modulators of the Staphylococcal Accessory Gene Regulator. J Med Chem. 2020 03 26; 63(6):2705-2730.
    View in: PubMed
    Score: 0.475
  16. Crosby HA, Tiwari N, Kwiecinski JM, Xu Z, Dykstra A, Jenul C, Fuentes EJ, Horswill AR. The Staphylococcus aureus ArlRS two-component system regulates virulence factor expression through MgrA. Mol Microbiol. 2020 01; 113(1):103-122.
    View in: PubMed
    Score: 0.474
  17. Kavanaugh JS, Flack CE, Lister J, Ricker EB, Ibberson CB, Jenul C, Moormeier DE, Delmain EA, Bayles KW, Horswill AR. Identification of Extracellular DNA-Binding Proteins in the Biofilm Matrix. mBio. 2019 06 25; 10(3).
    View in: PubMed
    Score: 0.463
  18. Kwiecinski JM, Crosby HA, Valotteau C, Hippensteel JA, Nayak MK, Chauhan AK, Schmidt EP, Dufrêne YF, Horswill AR. Staphylococcus aureus adhesion in endovascular infections is controlled by the ArlRS-MgrA signaling cascade. PLoS Pathog. 2019 05; 15(5):e1007800.
    View in: PubMed
    Score: 0.460
  19. Jenul C, Horswill AR. Regulation of Staphylococcus aureus Virulence. Microbiol Spectr. 2019 04 05; 7(2).
    View in: PubMed
    Score: 0.455
  20. Parlet CP, Brown MM, Horswill AR. Commensal Staphylococci Influence Staphylococcus aureus Skin Colonization and Disease. Trends Microbiol. 2019 06; 27(6):497-507.
    View in: PubMed
    Score: 0.453
  21. Loftus RW, Dexter F, Robinson ADM, Horswill AR. Desiccation tolerance is associated with Staphylococcus aureus hypertransmissibility, resistance and infection development in the operating room. J Hosp Infect. 2018 Nov; 100(3):299-308.
    View in: PubMed
    Score: 0.432
  22. Quave CL, Horswill AR. Identification of Staphylococcal Quorum Sensing Inhibitors by Quantification of õ-Hemolysin with High Performance Liquid Chromatography. Methods Mol Biol. 2018; 1673:363-370.
    View in: PubMed
    Score: 0.418
  23. Crosby HA, Kwiecinski J, Horswill AR. Staphylococcus aureus Aggregation and Coagulation Mechanisms, and Their Function in Host-Pathogen Interactions. Adv Appl Microbiol. 2016; 96:1-41.
    View in: PubMed
    Score: 0.379
  24. Ibberson CB, Parlet CP, Kwiecinski J, Crosby HA, Meyerholz DK, Horswill AR. Hyaluronan Modulation Impacts Staphylococcus aureus Biofilm Infection. Infect Immun. 2016 06; 84(6):1917-1929.
    View in: PubMed
    Score: 0.373
  25. Crosby HA, Schlievert PM, Merriman JA, King JM, Salgado-Pabón W, Horswill AR. The Staphylococcus aureus Global Regulator MgrA Modulates Clumping and Virulence by Controlling Surface Protein Expression. PLoS Pathog. 2016 05; 12(5):e1005604.
    View in: PubMed
    Score: 0.372
  26. Kavanaugh JS, Horswill AR. Impact of Environmental Cues on Staphylococcal Quorum Sensing and Biofilm Development. J Biol Chem. 2016 Jun 10; 291(24):12556-12564.
    View in: PubMed
    Score: 0.371
  27. Kiedrowski MR, Paharik AE, Ackermann LW, Shelton AU, Singh SB, Starner TD, Horswill AR. Development of an in vitro colonization model to investigate Staphylococcus aureus interactions with airway epithelia. Cell Microbiol. 2016 May; 18(5):720-32.
    View in: PubMed
    Score: 0.364
  28. Quave CL, Lyles JT, Kavanaugh JS, Nelson K, Parlet CP, Crosby HA, Heilmann KP, Horswill AR. Castanea sativa (European Chestnut) Leaf Extracts Rich in Ursene and Oleanene Derivatives Block Staphylococcus aureus Virulence and Pathogenesis without Detectable Resistance. PLoS One. 2015; 10(8):e0136486.
    View in: PubMed
    Score: 0.354
  29. Mootz JM, Benson MA, Heim CE, Crosby HA, Kavanaugh JS, Dunman PM, Kielian T, Torres VJ, Horswill AR. Rot is a key regulator of Staphylococcus aureus biofilm formation. Mol Microbiol. 2015 Apr; 96(2):388-404.
    View in: PubMed
    Score: 0.343
  30. Lister JL, Horswill AR. Staphylococcus aureus biofilms: recent developments in biofilm dispersal. Front Cell Infect Microbiol. 2014; 4:178.
    View in: PubMed
    Score: 0.339
  31. Ibberson CB, Jones CL, Singh S, Wise MC, Hart ME, Zurawski DV, Horswill AR. Staphylococcus aureus hyaluronidase is a CodY-regulated virulence factor. Infect Immun. 2014 Oct; 82(10):4253-64.
    View in: PubMed
    Score: 0.329
  32. Kiedrowski MR, Crosby HA, Hernandez FJ, Malone CL, McNamara JO, Horswill AR. Staphylococcus aureus Nuc2 is a functional, surface-attached extracellular nuclease. PLoS One. 2014; 9(4):e95574.
    View in: PubMed
    Score: 0.323
  33. Walker JN, Crosby HA, Spaulding AR, Salgado-Pabón W, Malone CL, Rosenthal CB, Schlievert PM, Boyd JM, Horswill AR. The Staphylococcus aureus ArlRS two-component system is a novel regulator of agglutination and pathogenesis. PLoS Pathog. 2013; 9(12):e1003819.
    View in: PubMed
    Score: 0.316
  34. Cech NB, Horswill AR. Small-molecule quorum quenchers to prevent Staphylococcus aureus infection. Future Microbiol. 2013 Dec; 8(12):1511-4.
    View in: PubMed
    Score: 0.315
  35. Mootz JM, Malone CL, Shaw LN, Horswill AR. Staphopains modulate Staphylococcus aureus biofilm integrity. Infect Immun. 2013 Sep; 81(9):3227-38.
    View in: PubMed
    Score: 0.305
  36. Olson ME, Horswill AR. Staphylococcus aureus osteomyelitis: bad to the bone. Cell Host Microbe. 2013 Jun 12; 13(6):629-31.
    View in: PubMed
    Score: 0.304
  37. Olson ME, King JM, Yahr TL, Horswill AR. Sialic acid catabolism in Staphylococcus aureus. J Bacteriol. 2013 Apr; 195(8):1779-88.
    View in: PubMed
    Score: 0.297
  38. Thoendel M, Horswill AR. Random mutagenesis and topology analysis of the autoinducing peptide biosynthesis proteins in Staphylococcus aureus. Mol Microbiol. 2013 Jan; 87(2):318-37.
    View in: PubMed
    Score: 0.294
  39. Kaplan JB, Izano EA, Gopal P, Karwacki MT, Kim S, Bose JL, Bayles KW, Horswill AR. Low levels of ß-lactam antibiotics induce extracellular DNA release and biofilm formation in Staphylococcus aureus. mBio. 2012; 3(4):e00198-12.
    View in: PubMed
    Score: 0.287
  40. Walker JN, Horswill AR. A coverslip-based technique for evaluating Staphylococcus aureus biofilm formation on human plasma. Front Cell Infect Microbiol. 2012; 2:39.
    View in: PubMed
    Score: 0.280
  41. Boles BR, Horswill AR. Staphylococcal biofilm disassembly. Trends Microbiol. 2011 Sep; 19(9):449-55.
    View in: PubMed
    Score: 0.267
  42. Boles BR, Thoendel M, Roth AJ, Horswill AR. Identification of genes involved in polysaccharide-independent Staphylococcus aureus biofilm formation. PLoS One. 2010 Apr 14; 5(4):e10146.
    View in: PubMed
    Score: 0.245
  43. Thoendel M, Horswill AR. Identification of Staphylococcus aureus AgrD residues required for autoinducing peptide biosynthesis. J Biol Chem. 2009 Aug 14; 284(33):21828-21838.
    View in: PubMed
    Score: 0.231
  44. Malone CL, Boles BR, Lauderdale KJ, Thoendel M, Kavanaugh JS, Horswill AR. Fluorescent reporters for Staphylococcus aureus. J Microbiol Methods. 2009 Jun; 77(3):251-60.
    View in: PubMed
    Score: 0.226
  45. Lauderdale KJ, Boles BR, Cheung AL, Horswill AR. Interconnections between Sigma B, agr, and proteolytic activity in Staphylococcus aureus biofilm maturation. Infect Immun. 2009 Apr; 77(4):1623-35.
    View in: PubMed
    Score: 0.225
  46. Horswill AR, Nauseef WM. Host interception of bacterial communication signals. Cell Host Microbe. 2008 Dec 11; 4(6):507-9.
    View in: PubMed
    Score: 0.223
  47. Boles BR, Horswill AR. Agr-mediated dispersal of Staphylococcus aureus biofilms. PLoS Pathog. 2008 Apr 25; 4(4):e1000052.
    View in: PubMed
    Score: 0.213
  48. Malone CL, Boles BR, Horswill AR. Biosynthesis of Staphylococcus aureus autoinducing peptides by using the synechocystis DnaB mini-intein. Appl Environ Microbiol. 2007 Oct; 73(19):6036-44.
    View in: PubMed
    Score: 0.203
  49. Kavanaugh JS, Thoendel M, Horswill AR. A role for type I signal peptidase in Staphylococcus aureus quorum sensing. Mol Microbiol. 2007 Aug; 65(3):780-98.
    View in: PubMed
    Score: 0.202
  50. Teghanemt A, Schilcher K, Kavanaugh JS, Horswill AR, Nauseef WM. Mutation in Staphylococcus aureus that supports gain of function in susceptibility both to hypochlorous acid and to human neutrophils. J Leukoc Biol. 2025 Jul 09; 117(7).
    View in: PubMed
    Score: 0.176
  51. Cohen S, Horswill AR, Doran KS. Skin mycobiome: Fungi drive colonization resistance in an already hostile environment. Curr Biol. 2025 May 19; 35(10):R396-R398.
    View in: PubMed
    Score: 0.174
  52. Tamkin E, Lorenz BP, McCarty A, Fulte S, Eisenmesser E, Horswill AR, Clark SE. Airway Corynebacterium interfere with Streptococcus pneumoniae and Staphylococcus aureus infection and express secreted factors selectively targeting each pathogen. Infect Immun. 2025 02 18; 93(2):e0044524.
    View in: PubMed
    Score: 0.169
  53. Costa FG, Mills KB, Crosby HA, Horswill AR. The Staphylococcus aureus regulatory program in a human skin-like environment. mBio. 2024 May 08; 15(5):e0045324.
    View in: PubMed
    Score: 0.161
  54. Crosby HA, Keim K, Kwiecinski JM, Langouët-Astrié CJ, Oshima K, LaRivière WB, Schmidt EP, Horswill AR. Host-derived protease promotes aggregation of Staphylococcus aureus by cleaving the surface protein SasG. mBio. 2024 Apr 10; 15(4):e0348323.
    View in: PubMed
    Score: 0.161
  55. Bhattacharya M, Horswill AR. The role of human extracellular matrix proteins in defining Staphylococcus aureus biofilm infections. FEMS Microbiol Rev. 2024 Jan 12; 48(1).
    View in: PubMed
    Score: 0.159
  56. Deng L, Costa F, Blake KJ, Choi S, Chandrabalan A, Yousuf MS, Shiers S, Dubreuil D, Vega-Mendoza D, Rolland C, Deraison C, Voisin T, Bagood MD, Wesemann L, Frey AM, Palumbo JS, Wainger BJ, Gallo RL, Leyva-Castillo JM, Vergnolle N, Price TJ, Ramachandran R, Horswill AR, Chiu IM. S. aureus drives itch and scratch-induced skin damage through a V8 protease-PAR1 axis. Cell. 2023 11 22; 186(24):5375-5393.e25.
    View in: PubMed
    Score: 0.157
  57. Jenul C, Keim KC, Jens JN, Zeiler MJ, Schilcher K, Schurr MJ, Melander C, Phelan VV, Horswill AR. Pyochelin biotransformation by Staphylococcus aureus shapes bacterial competition with Pseudomonas aeruginosa in polymicrobial infections. Cell Rep. 2023 06 27; 42(6):112540.
    View in: PubMed
    Score: 0.152
  58. Staats A, Burback PW, Casillas-Ituarte NN, Li D, Hostetler MR, Sullivan A, Horswill AR, Lower SK, Stoodley P. In Vitro Staphylococcal Aggregate Morphology and Protection from Antibiotics Are Dependent on Distinct Mechanisms Arising from Postsurgical Joint Components and Fluid Motion. J Bacteriol. 2023 04 25; 205(4):e0045122.
    View in: PubMed
    Score: 0.150
  59. Lyon LM, Doran KS, Horswill AR. Staphylococcus aureus Fibronectin-Binding Proteins Contribute to Colonization of the Female Reproductive Tract. Infect Immun. 2023 01 24; 91(1):e0046022.
    View in: PubMed
    Score: 0.147
  60. Mills KB, Roy P, Kwiecinski JM, Fey PD, Horswill AR. Staphylococcal Corneocyte Adhesion: Assay Optimization and Roles of Aap and SasG Adhesins in the Establishment of Healthy Skin Colonization. Microbiol Spectr. 2022 12 21; 10(6):e0246922.
    View in: PubMed
    Score: 0.145
  61. Lee J, Carda-Diéguez M, ?iemyte M, Vreugde S, Cooksley C, Crosby HA, Horswill AR, Mira A, Zilm PS, Kidd SP. Functional mgrA Influences Genetic Changes within a Staphylococcus aureus Cell Population over Time. J Bacteriol. 2022 Oct 18; 204(10):e0013822.
    View in: PubMed
    Score: 0.145
  62. Kwiecinski JM, Jelani DA, Fuentes EJ, Horswill AR. Therapeutic Inhibition of Staphylococcus aureus ArlRS Two-Component Regulatory System Blocks Virulence. Antimicrob Agents Chemother. 2022 07 19; 66(7):e0018722.
    View in: PubMed
    Score: 0.142
  63. de Vor L, van Dijk B, van Kessel K, Kavanaugh JS, de Haas C, Aerts PC, Viveen MC, Boel EC, Fluit AC, Kwiecinski JM, Krijger GC, Ramakers RM, Beekman FJ, Dadachova E, Lam MG, Vogely HC, van der Wal BC, van Strijp JA, Horswill AR, Weinans H, Rooijakkers SH. Human monoclonal antibodies against Staphylococcus aureus surface antigens recognize in vitro and in vivo biofilm. Elife. 2022 01 06; 11.
    View in: PubMed
    Score: 0.138
  64. Nakamura K, Williams MR, Kwiecinski JM, Horswill AR, Gallo RL. Staphylococcus aureus Enters Hair Follicles Using Triacylglycerol Lipases Preserved through the Genus Staphylococcus. J Invest Dermatol. 2021 08; 141(8):2094-2097.
    View in: PubMed
    Score: 0.130
  65. Gupta TT, Gupta NK, Pestrak MJ, Dusane DH, Harro JM, Horswill AR, Stoodley P. Staphylococcus aureus Aggregates on Orthopedic Materials under Varying Levels of Shear Stress. Appl Environ Microbiol. 2020 09 17; 86(19).
    View in: PubMed
    Score: 0.126
  66. Tang H, Porras G, Brown MM, Chassagne F, Lyles JT, Bacsa J, Horswill AR, Quave CL. Triterpenoid acids isolated from Schinus terebinthifolia fruits reduce Staphylococcus aureus virulence and abate dermonecrosis. Sci Rep. 2020 05 15; 10(1):8046.
    View in: PubMed
    Score: 0.123
  67. Pestrak MJ, Gupta TT, Dusane DH, Guzior DV, Staats A, Harro J, Horswill AR, Stoodley P. Investigation of synovial fluid induced Staphylococcus aureus aggregate development and its impact on surface attachment and biofilm formation. PLoS One. 2020; 15(4):e0231791.
    View in: PubMed
    Score: 0.122
  68. Williams MR, Cau L, Wang Y, Kaul D, Sanford JA, Zaramela LS, Khalil S, Butcher AM, Zengler K, Horswill AR, Dupont CL, Hovnanian A, Gallo RL. Interplay of Staphylococcal and Host Proteases Promotes Skin Barrier Disruption in Netherton Syndrome. Cell Rep. 2020 03 03; 30(9):2923-2933.e7.
    View in: PubMed
    Score: 0.121
  69. DelMain EA, Moormeier DE, Endres JL, Hodges RE, Sadykov MR, Horswill AR, Bayles KW. Stochastic Expression of Sae-Dependent Virulence Genes during Staphylococcus aureus Biofilm Development Is Dependent on SaeS. mBio. 2020 01 14; 11(1).
    View in: PubMed
    Score: 0.120
  70. Sirobhushanam S, Parsa N, Reed TJ, Berthier CC, Sarkar MK, Hile GA, Tsoi LC, Banfield J, Dobry C, Horswill AR, Gudjonsson JE, Kahlenberg JM. Staphylococcus aureus Colonization Is Increased on Lupus Skin Lesions and Is Promoted by IFN-Mediated Barrier Disruption. J Invest Dermatol. 2020 05; 140(5):1066-1074.e4.
    View in: PubMed
    Score: 0.120
  71. Borbón TY, Scorza BM, Clay GM, Lima Nobre de Queiroz F, Sariol AJ, Bowen JL, Chen Y, Zhanbolat B, Parlet CP, Valadares DG, Cassel SL, Nauseef WM, Horswill AR, Sutterwala FS, Wilson ME. Coinfection with Leishmania major and Staphylococcus aureus enhances the pathologic responses to both microbes through a pathway involving IL-17A. PLoS Negl Trop Dis. 2019 05; 13(5):e0007247.
    View in: PubMed
    Score: 0.115
  72. Kwiecinski JM, Jacobsson G, Horswill AR, Josefsson E, Jin T. Biofilm formation by Staphylococcus aureus clinical isolates correlates with the infection type. Infect Dis (Lond). 2019 06; 51(6):446-451.
    View in: PubMed
    Score: 0.114
  73. Mlynek KD, Callahan MT, Shimkevitch AV, Farmer JT, Endres JL, Marchand M, Bayles KW, Horswill AR, Kaplan JB. Effects of Low-Dose Amoxicillin on Staphylococcus aureus USA300 Biofilms. Antimicrob Agents Chemother. 2016 05; 60(5):2639-51.
    View in: PubMed
    Score: 0.093
  74. Herrera A, Vu BG, Stach CS, Merriman JA, Horswill AR, Salgado-Pabón W, Schlievert PM. Staphylococcus aureus ß-Toxin Mutants Are Defective in Biofilm Ligase and Sphingomyelinase Activity, and Causation of Infective Endocarditis and Sepsis. Biochemistry. 2016 05 03; 55(17):2510-7.
    View in: PubMed
    Score: 0.093
  75. Paharik AE, Horswill AR. The Staphylococcal Biofilm: Adhesins, Regulation, and Host Response. Microbiol Spectr. 2016 04; 4(2).
    View in: PubMed
    Score: 0.092
  76. Scherr TD, Hanke ML, Huang O, James DB, Horswill AR, Bayles KW, Fey PD, Torres VJ, Kielian T. Staphylococcus aureus Biofilms Induce Macrophage Dysfunction Through Leukocidin AB and Alpha-Toxin. mBio. 2015 Aug 25; 6(4).
    View in: PubMed
    Score: 0.089
  77. Abou Alaiwa MH, Reznikov LR, Gansemer ND, Sheets KA, Horswill AR, Stoltz DA, Zabner J, Welsh MJ. pH modulates the activity and synergism of the airway surface liquid antimicrobials ß-defensin-3 and LL-37. Proc Natl Acad Sci U S A. 2014 Dec 30; 111(52):18703-8.
    View in: PubMed
    Score: 0.085
  78. Moormeier DE, Bose JL, Horswill AR, Bayles KW. Temporal and stochastic control of Staphylococcus aureus biofilm development. mBio. 2014 Oct 14; 5(5):e01341-14.
    View in: PubMed
    Score: 0.084
  79. DeLeon S, Clinton A, Fowler H, Everett J, Horswill AR, Rumbaugh KP. Synergistic interactions of Pseudomonas aeruginosa and Staphylococcus aureus in an in vitro wound model. Infect Immun. 2014 Nov; 82(11):4718-28.
    View in: PubMed
    Score: 0.083
  80. Sully EK, Malachowa N, Elmore BO, Alexander SM, Femling JK, Gray BM, DeLeo FR, Otto M, Cheung AL, Edwards BS, Sklar LA, Horswill AR, Hall PR, Gresham HD. Selective chemical inhibition of agr quorum sensing in Staphylococcus aureus promotes host defense with minimal impact on resistance. PLoS Pathog. 2014 Jun; 10(6):e1004174.
    View in: PubMed
    Score: 0.082
  81. Flack CE, Zurek OW, Meishery DD, Pallister KB, Malone CL, Horswill AR, Voyich JM. Differential regulation of staphylococcal virulence by the sensor kinase SaeS in response to neutrophil-derived stimuli. Proc Natl Acad Sci U S A. 2014 May 13; 111(19):E2037-45.
    View in: PubMed
    Score: 0.081
  82. White MJ, Boyd JM, Horswill AR, Nauseef WM. Phosphatidylinositol-specific phospholipase C contributes to survival of Staphylococcus aureus USA300 in human blood and neutrophils. Infect Immun. 2014 Apr; 82(4):1559-71.
    View in: PubMed
    Score: 0.079
  83. Snowden JN, Beaver M, Beenken K, Smeltzer M, Horswill AR, Kielian T. Staphylococcus aureus sarA regulates inflammation and colonization during central nervous system biofilm formation. PLoS One. 2013; 8(12):e84089.
    View in: PubMed
    Score: 0.079
  84. Pang YY, Schwartz J, Bloomberg S, Boyd JM, Horswill AR, Nauseef WM. Methionine sulfoxide reductases protect against oxidative stress in Staphylococcus aureus encountering exogenous oxidants and human neutrophils. J Innate Immun. 2014; 6(3):353-64.
    View in: PubMed
    Score: 0.078
  85. Chiu IM, Heesters BA, Ghasemlou N, Von Hehn CA, Zhao F, Tran J, Wainger B, Strominger A, Muralidharan S, Horswill AR, Bubeck Wardenburg J, Hwang SW, Carroll MC, Woolf CJ. Bacteria activate sensory neurons that modulate pain and inflammation. Nature. 2013 Sep 05; 501(7465):52-7.
    View in: PubMed
    Score: 0.077
  86. Spaulding AR, Salgado-Pabón W, Kohler PL, Horswill AR, Leung DY, Schlievert PM. Staphylococcal and streptococcal superantigen exotoxins. Clin Microbiol Rev. 2013 Jul; 26(3):422-47.
    View in: PubMed
    Score: 0.076
  87. Zurek OW, Nygaard TK, Watkins RL, Pallister KB, Torres VJ, Horswill AR, Voyich JM. The role of innate immunity in promoting SaeR/S-mediated virulence in Staphylococcus aureus. J Innate Immun. 2014; 6(1):21-30.
    View in: PubMed
    Score: 0.076
  88. Junio HA, Todd DA, Ettefagh KA, Ehrmann BM, Kavanaugh JS, Horswill AR, Cech NB. Quantitative analysis of autoinducing peptide I (AIP-I) from Staphylococcus aureus cultures using ultrahigh performance liquid chromatography-high resolving power mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Jul 01; 930:7-12.
    View in: PubMed
    Score: 0.075
  89. Moormeier DE, Endres JL, Mann EE, Sadykov MR, Horswill AR, Rice KC, Fey PD, Bayles KW. Use of microfluidic technology to analyze gene expression during Staphylococcus aureus biofilm formation reveals distinct physiological niches. Appl Environ Microbiol. 2013 Jun; 79(11):3413-24.
    View in: PubMed
    Score: 0.075
  90. Hall PR, Elmore BO, Spang CH, Alexander SM, Manifold-Wheeler BC, Castleman MJ, Daly SM, Peterson MM, Sully EK, Femling JK, Otto M, Horswill AR, Timmins GS, Gresham HD. Nox2 modification of LDL is essential for optimal apolipoprotein B-mediated control of agr type III Staphylococcus aureus quorum-sensing. PLoS Pathog. 2013 Feb; 9(2):e1003166.
    View in: PubMed
    Score: 0.074
  91. Olson ME, Nygaard TK, Ackermann L, Watkins RL, Zurek OW, Pallister KB, Griffith S, Kiedrowski MR, Flack CE, Kavanaugh JS, Kreiswirth BN, Horswill AR, Voyich JM. Staphylococcus aureus nuclease is an SaeRS-dependent virulence factor. Infect Immun. 2013 Apr; 81(4):1316-24.
    View in: PubMed
    Score: 0.074
  92. Zielinska AK, Beenken KE, Mrak LN, Spencer HJ, Post GR, Skinner RA, Tackett AJ, Horswill AR, Smeltzer MS. sarA-mediated repression of protease production plays a key role in the pathogenesis of Staphylococcus aureus USA300 isolates. Mol Microbiol. 2012 Dec; 86(5):1183-96.
    View in: PubMed
    Score: 0.073
  93. Kiedrowski MR, Horswill AR. New approaches for treating staphylococcal biofilm infections. Ann N Y Acad Sci. 2011 Dec; 1241:104-21.
    View in: PubMed
    Score: 0.068
  94. Wörmann ME, Reichmann NT, Malone CL, Horswill AR, Gründling A. Proteolytic cleavage inactivates the Staphylococcus aureus lipoteichoic acid synthase. J Bacteriol. 2011 Oct; 193(19):5279-91.
    View in: PubMed
    Score: 0.067
  95. Lin YC, Anderson MJ, Kohler PL, Strandberg KL, Olson ME, Horswill AR, Schlievert PM, Peterson ML. Proinflammatory exoprotein characterization of toxic shock syndrome Staphylococcus aureus. Biochemistry. 2011 Aug 23; 50(33):7157-67.
    View in: PubMed
    Score: 0.067
  96. Benson MA, Lilo S, Wasserman GA, Thoendel M, Smith A, Horswill AR, Fraser J, Novick RP, Shopsin B, Torres VJ. Staphylococcus aureus regulates the expression and production of the staphylococcal superantigen-like secreted proteins in a Rot-dependent manner. Mol Microbiol. 2011 Aug; 81(3):659-75.
    View in: PubMed
    Score: 0.066
  97. Thurlow LR, Hanke ML, Fritz T, Angle A, Aldrich A, Williams SH, Engebretsen IL, Bayles KW, Horswill AR, Kielian T. Staphylococcus aureus biofilms prevent macrophage phagocytosis and attenuate inflammation in vivo. J Immunol. 2011 Jun 01; 186(11):6585-96.
    View in: PubMed
    Score: 0.066
  98. Laarman AJ, Ruyken M, Malone CL, van Strijp JA, Horswill AR, Rooijakkers SH. Staphylococcus aureus metalloprotease aureolysin cleaves complement C3 to mediate immune evasion. J Immunol. 2011 Jun 01; 186(11):6445-53.
    View in: PubMed
    Score: 0.066
  99. Kirchdoerfer RN, Garner AL, Flack CE, Mee JM, Horswill AR, Janda KD, Kaufmann GF, Wilson IA. Structural basis for ligand recognition and discrimination of a quorum-quenching antibody. J Biol Chem. 2011 May 13; 286(19):17351-8.
    View in: PubMed
    Score: 0.065
  100. Hammond AA, Miller KG, Kruczek CJ, Dertien J, Colmer-Hamood JA, Griswold JA, Horswill AR, Hamood AN. An in vitro biofilm model to examine the effect of antibiotic ointments on biofilms produced by burn wound bacterial isolates. Burns. 2011 Mar; 37(2):312-21.
    View in: PubMed
    Score: 0.064
  101. Beenken KE, Mrak LN, Griffin LM, Zielinska AK, Shaw LN, Rice KC, Horswill AR, Bayles KW, Smeltzer MS. Epistatic relationships between sarA and agr in Staphylococcus aureus biofilm formation. PLoS One. 2010 May 24; 5(5):e10790.
    View in: PubMed
    Score: 0.062
  102. Mann EE, Rice KC, Boles BR, Endres JL, Ranjit D, Chandramohan L, Tsang LH, Smeltzer MS, Horswill AR, Bayles KW. Modulation of eDNA release and degradation affects Staphylococcus aureus biofilm maturation. PLoS One. 2009 Jun 09; 4(6):e5822.
    View in: PubMed
    Score: 0.058
  103. Hook JS, Matheis AD, Kavanaugh JS, Horswill AR, Moreland JG. Role for IRAK-4 and p38 in Neutrophil Signaling in Response to Bacterial Lipoproteins from Staphylococcus aureus. Inflammation. 2025 Aug; 48(4):1704-1715.
    View in: PubMed
    Score: 0.042
  104. Eisenbraun EL, Vulpis TD, Prosser BN, Horswill AR, Blackwell HE. Synthetic Peptides Capable of Potent Multigroup Staphylococcal Quorum Sensing Activation and Inhibition in Both Cultures and Biofilm Communities. J Am Chem Soc. 2024 Jun 12; 146(23):15941-15954.
    View in: PubMed
    Score: 0.041
  105. Weig AW, O'Conner PM, Kwiecinski JM, Marciano OM, Nunag A, Gutierrez AT, Melander RJ, Horswill AR, Melander C. A structure activity relationship study of 3,4'-dimethoxyflavone for ArlRS inhibition in Staphylococcus aureus. Org Biomol Chem. 2023 04 26; 21(16):3373-3380.
    View in: PubMed
    Score: 0.038
  106. Hinman KD, Laforce-Nesbitt SS, Cohen JT, Mundy M, Bliss JM, Horswill AR, Lefort CT. Bi-fluorescent Staphylococcus aureus infection enables single-cell analysis of intracellular killing in vivo. Front Immunol. 2023; 14:1089111.
    View in: PubMed
    Score: 0.037
  107. Haynes AS, Prinzi A, Silveira LJ, Parker SK, Lampe JN, Kavanaugh JS, Horswill AR, Fish D. Cefadroxil Comparable to Cephalexin: Minimum Inhibitory Concentrations among Methicillin-Susceptible Staphylococcus aureus Isolates from Pediatric Musculoskeletal Infections. Microbiol Spectr. 2022 08 31; 10(4):e0103922.
    View in: PubMed
    Score: 0.036
  108. Staats A, Burback PW, Schwieters A, Li D, Sullivan A, Horswill AR, Stoodley P. Rapid Aggregation of Staphylococcus aureus in Synovial Fluid Is Influenced by Synovial Fluid Concentration, Viscosity, and Fluid Dynamics, with Evidence of Polymer Bridging. mBio. 2022 04 26; 13(2):e0023622.
    View in: PubMed
    Score: 0.035
  109. Nakamura K, O'Neill AM, Williams MR, Cau L, Nakatsuji T, Horswill AR, Gallo RL. Short chain fatty acids produced by Cutibacterium acnes inhibit biofilm formation by Staphylococcus epidermidis. Sci Rep. 2020 12 04; 10(1):21237.
    View in: PubMed
    Score: 0.032
  110. Bispo M, Anaya-Sanchez A, Suhani S, Raineri EJM, López-Álvarez M, Heuker M, Szymanski W, Romero Pastrana F, Buist G, Horswill AR, Francis KP, van Dam GM, van Oosten M, van Dijl JM. Fighting Staphylococcus aureus infections with light and photoimmunoconjugates. JCI Insight. 2020 11 19; 5(22).
    View in: PubMed
    Score: 0.032
  111. Miller RJ, Crosby HA, Schilcher K, Wang Y, Ortines RV, Mazhar M, Dikeman DA, Pinsker BL, Brown ID, Joyce DP, Zhang J, Archer NK, Liu H, Alphonse MP, Czupryna J, Anderson WR, Bernthal NM, Fortuno-Miranda L, Bulte JWM, Francis KP, Horswill AR, Miller LS. Development of a Staphylococcus aureus reporter strain with click beetle red luciferase for enhanced in vivo imaging of experimental bacteremia and mixed infections. Sci Rep. 2019 11 13; 9(1):16663.
    View in: PubMed
    Score: 0.030
  112. Urbano R, Karlinsey JE, Libby SJ, Doulias PT, Ischiropoulos H, Warheit-Niemi HI, Liggitt DH, Horswill AR, Fang FC. Host Nitric Oxide Disrupts Microbial Cell-to-Cell Communication to Inhibit Staphylococcal Virulence. Cell Host Microbe. 2018 05 09; 23(5):594-606.e7.
    View in: PubMed
    Score: 0.027
  113. Parlet CP, Kavanaugh JS, Horswill AR, Schlueter AJ. Chronic ethanol feeding increases the severity of Staphylococcus aureus skin infections by altering local host defenses. J Leukoc Biol. 2015 Apr; 97(4):769-78.
    View in: PubMed
    Score: 0.021
  114. Sommerfeld Ross S, Tu MH, Falsetta ML, Ketterer MR, Kiedrowski MR, Horswill AR, Apicella MA, Reinhardt JM, Fiegel J. Quantification of confocal images of biofilms grown on irregular surfaces. J Microbiol Methods. 2014 May; 100:111-20.
    View in: PubMed
    Score: 0.020
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