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Leptin in human plasma is derived in part from the brain, and cleared by the kidneys.

Esler M, Vaz M, Collier G, Nestel P, Jennings G, Kaye D, Seals D, Lambert G. Leptin in human plasma is derived in part from the brain, and cleared by the kidneys. Lancet. 1998 Mar 21; 351(9106):879.

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