 Connection
Tunuguntla Kumar to Mice
This is a "connection" page, showing publications Tunuguntla Kumar has written about Mice.
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Connection Strength |
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1.078 |
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Kumar TR. Cre Deleter Mouse Lines for Conditional Knockout of Genes in Testis Cell Types. Methods Mol Biol. 2025; 2954:287-294.
Score: 0.068
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McDonald R, Larsen M, Liu Z, Southekal S, Eudy J, Guda C, Kumar TR. RNA-seq analysis identifies age-dependent changes in expression of mRNAs - encoding N-glycosylation pathway enzymes in mouse gonadotropes. Mol Cell Endocrinol. 2023 08 20; 574:111971.
Score: 0.061
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Kumar TR. Rerouting of follicle-stimulating hormone secretion and gonadal function. Fertil Steril. 2023 02; 119(2):180-183.
Score: 0.059
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Liu Z, Wang H, Larsen M, Gunewardana S, Cendali FI, Reisz JA, Akiyama H, Behringer RR, Ma Q, Hammoud SS, Kumar TR. The solute carrier family 7 member 11 (SLC7A11) is regulated by LH/androgen and required for cystine/glutathione homeostasis in mouse Sertoli cells. Mol Cell Endocrinol. 2022 06 01; 549:111641.
Score: 0.056
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Kumar TR. An interview with Dr Richard Behringer. Biol Reprod. 2019 01 01; 100(1):8-10.
Score: 0.045
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Kumar TR. The SO(H)L(H) "O" drivers of oocyte growth and survival but not meiosis I. J Clin Invest. 2017 Jun 01; 127(6):2044-2047.
Score: 0.040
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Wang H, Hastings R, Miller WL, Kumar TR. Fshb-iCre mice are efficient and specific Cre deleters for the gonadotrope lineage. Mol Cell Endocrinol. 2016 Jan 05; 419:124-38.
Score: 0.036
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Wang H, Graham I, Hastings R, Gunewardena S, Brinkmeier ML, Conn PM, Camper SA, Kumar TR. Gonadotrope-specific deletion of Dicer results in severely suppressed gonadotropins and fertility defects. J Biol Chem. 2015 Jan 30; 290(5):2699-714.
Score: 0.034
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Wang H, Larson M, Jablonka-Shariff A, Pearl CA, Miller WL, Conn PM, Boime I, Kumar TR. Redirecting intracellular trafficking and the secretion pattern of FSH dramatically enhances ovarian function in mice. Proc Natl Acad Sci U S A. 2014 Apr 15; 111(15):5735-40.
Score: 0.032
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Wang H, Kumar TR. Segment- and cell-specific expression of D-type cyclins in the postnatal mouse epididymis. Gene Expr Patterns. 2012 Mar-Apr; 12(3-4):136-44.
Score: 0.028
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Kumar TR. The "Glow"rious Sertoli and germ cells: mouse testis development visualized in multi-colors. Biol Reprod. 2011 Feb; 84(2):201-4.
Score: 0.025
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Kumar TR. FSHbeta knockout mouse model: a decade ago and into the future. Endocrine. 2009 Aug; 36(1):1-5.
Score: 0.023
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Kumar TR, Larson M, Wang H, McDermott J, Bronshteyn I. Transgenic mouse technology: principles and methods. Methods Mol Biol. 2009; 590:335-62.
Score: 0.022
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Kumar TR. Functional analysis of LHbeta knockout mice. Mol Cell Endocrinol. 2007 Apr 15; 269(1-2):81-4.
Score: 0.020
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Kumar TR. Mouse models for gonadotropins: a 15-year saga. Mol Cell Endocrinol. 2007 Jan 02; 260-262:249-54.
Score: 0.019
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Kumar TR, Schuff KG, Nusser KD, Low MJ. Gonadotroph-specific expression of the human follicle stimulating hormone beta gene in transgenic mice. Mol Cell Endocrinol. 2006 Mar 09; 247(1-2):103-15.
Score: 0.018
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Kumar TR. What have we learned about gonadotropin function from gonadotropin subunit and receptor knockout mice? Reproduction. 2005 Sep; 130(3):293-302.
Score: 0.018
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Ma X, Reyna A, Mani SK, Matzuk MM, Kumar TR. Impaired male sexual behavior in activin receptor type II knockout mice. Biol Reprod. 2005 Dec; 73(6):1182-90.
Score: 0.018
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Kumar TR. Gonadotropin gene targeting and biological implications. Endocrine. 2005 Apr; 26(3):227-33.
Score: 0.017
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Ma X, Dong Y, Matzuk MM, Kumar TR. Targeted disruption of luteinizing hormone beta-subunit leads to hypogonadism, defects in gonadal steroidogenesis, and infertility. Proc Natl Acad Sci U S A. 2004 Dec 07; 101(49):17294-9.
Score: 0.017
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Garcia-Campayo V, Boime I, Ma X, Daphna-Iken D, Kumar TR. A single-chain tetradomain glycoprotein hormone analog elicits multiple hormone activities in vivo. Biol Reprod. 2005 Feb; 72(2):301-8.
Score: 0.017
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Kumar TR, Vasantha Bai M, Krishnan LK. A freeze-dried fibrin disc as a biodegradable drug release matrix. Biologicals. 2004 Mar; 32(1):49-55.
Score: 0.016
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Kumar TR, Agno J, Janovick JA, Conn PM, Matzuk MM. Regulation of FSHbeta and GnRH receptor gene expression in activin receptor II knockout male mice. Mol Cell Endocrinol. 2003 Dec 30; 212(1-2):19-27.
Score: 0.016
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Matzuk MM, DeMayo FJ, Hadsell LA, Kumar TR. Overexpression of human chorionic gonadotropin causes multiple reproductive defects in transgenic mice. Biol Reprod. 2003 Jul; 69(1):338-46.
Score: 0.015
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Kumar TR, Varani S, Wreford NG, Telfer NM, de Kretser DM, Matzuk MM. Male reproductive phenotypes in double mutant mice lacking both FSHbeta and activin receptor IIA. Endocrinology. 2001 Aug; 142(8):3512-8.
Score: 0.013
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Kumar TR, Wiseman AL, Kala G, Kala SV, Matzuk MM, Lieberman MW. Reproductive defects in gamma-glutamyl transpeptidase-deficient mice. Endocrinology. 2000 Nov; 141(11):4270-7.
Score: 0.013
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Simon LE, Liu Z, Bousfield GR, Kumar TR, Duncan FE. Recombinant FSH glycoforms are bioactive in mouse preantral ovarian follicles. Reproduction. 2019 12; 158(6):517-527.
Score: 0.012
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Kumar TR. Male-mediated dominant lethal mutations in mice following prooxidant treatment. Mutat Res. 1999 Jul 21; 444(1):145-9.
Score: 0.012
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Kumar TR, Palapattu G, Wang P, Woodruff TK, Boime I, Byrne MC, Matzuk MM. Transgenic models to study gonadotropin function: the role of follicle-stimulating hormone in gonadal growth and tumorigenesis. Mol Endocrinol. 1999 Jun; 13(6):851-65.
Score: 0.012
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Anjana S, Joseph J, John J, Balachandran S, Kumar TRS, Abraham A. Novel flourescent spiroborate esters: potential therapeutic agents in in vitro cancer models. Mol Biol Rep. 2019 Feb; 46(1):727-740.
Score: 0.011
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Roy S, Gandra D, Seger C, Biswas A, Kushnir VA, Gleicher N, Kumar TR, Sen A. Oocyte-Derived Factors (GDF9 and BMP15) and FSH Regulate AMH Expression Via Modulation of H3K27AC in Granulosa Cells. Endocrinology. 2018 09 01; 159(9):3433-3445.
Score: 0.011
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Kumar TR, Low MJ, Matzuk MM. Genetic rescue of follicle-stimulating hormone beta-deficient mice. Endocrinology. 1998 Jul; 139(7):3289-95.
Score: 0.011
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Kumar TR, Graham KE, Asa SL, Low MJ. Simian virus 40 T antigen-induced gonadotroph adenomas: a model of human null cell adenomas. Endocrinology. 1998 Jul; 139(7):3342-51.
Score: 0.011
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Liu P, Ji Y, Yuen T, Rendina-Ruedy E, DeMambro VE, Dhawan S, Abu-Amer W, Izadmehr S, Zhou B, Shin AC, Latif R, Thangeswaran P, Gupta A, Li J, Shnayder V, Robinson ST, Yu YE, Zhang X, Yang F, Lu P, Zhou Y, Zhu LL, Oberlin DJ, Davies TF, Reagan MR, Brown A, Kumar TR, Epstein S, Iqbal J, Avadhani NG, New MI, Molina H, van Klinken JB, Guo EX, Buettner C, Haider S, Bian Z, Sun L, Rosen CJ, Zaidi M. Blocking FSH induces thermogenic adipose tissue and reduces body fat. Nature. 2017 06 01; 546(7656):107-112.
Score: 0.010
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Kumar TR, Wang Y, Lu N, Matzuk MM. Follicle stimulating hormone is required for ovarian follicle maturation but not male fertility. Nat Genet. 1997 Feb; 15(2):201-4.
Score: 0.010
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Kumar TR, Wang Y, Matzuk MM. Gonadotropins are essential modifier factors for gonadal tumor development in inhibin-deficient mice. Endocrinology. 1996 Oct; 137(10):4210-6.
Score: 0.010
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Arora A, Deniskin R, Sosa Y, Nishtala SN, Henrich PP, Kumar TR, Fidock DA, Akabas MH. Substrate and Inhibitor Specificity of the Plasmodium berghei Equilibrative Nucleoside Transporter Type 1. Mol Pharmacol. 2016 06; 89(6):678-85.
Score: 0.009
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Kumar TR, Kelly M, Mortrud M, Low MJ, Matzuk MM. Cloning of the mouse gonadotropin beta-subunit-encoding genes, I. Structure of the follicle-stimulating hormone beta-subunit-encoding gene. Gene. 1995 Dec 12; 166(2):333-4.
Score: 0.009
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Kumar TR, Matzuk MM. Cloning of the mouse gonadotropin beta-subunit-encoding genes, II. Structure of the luteinizing hormone beta-subunit-encoding genes. Gene. 1995 Dec 12; 166(2):335-6.
Score: 0.009
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Kumar TR, Donehower LA, Bradley A, Matzuk MM. Transgenic mouse models for tumour-suppressor genes. J Intern Med. 1995 Sep; 238(3):233-8.
Score: 0.009
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Kumar TR, Low MJ. Hormonal regulation of human follicle-stimulating hormone-beta subunit gene expression: GnRH stimulation and GnRH-independent androgen inhibition. Neuroendocrinology. 1995 Jun; 61(6):628-37.
Score: 0.009
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Abel MH, Widen A, Wang X, Huhtaniemi I, Pakarinen P, Kumar TR, Christian HC. Pituitary gonadotrophic hormone synthesis, secretion, subunit gene expression and cell structure in normal and follicle-stimulating hormone ß knockout, follicle-stimulating hormone receptor knockout, luteinising hormone receptor knockout, hypogonadal and ovariectomised female mice. J Neuroendocrinol. 2014 Nov; 26(11):785-95.
Score: 0.008
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Abel MH, Charlton HM, Huhtaniemi I, Pakarinen P, Kumar TR, Christian HC. An investigation into pituitary gonadotrophic hormone synthesis, secretion, subunit gene expression and cell structure in normal and mutant male mice. J Neuroendocrinol. 2013 Oct; 25(10):863-75.
Score: 0.008
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Kumar TR, Low MJ. Gonadal steroid hormone regulation of human and mouse follicle stimulating hormone beta-subunit gene expression in vivo. Mol Endocrinol. 1993 Jul; 7(7):898-906.
Score: 0.008
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Oury F, Ferron M, Huizhen W, Confavreux C, Xu L, Lacombe J, Srinivas P, Chamouni A, Lugani F, Lejeune H, Kumar TR, Plotton I, Karsenty G. Osteocalcin regulates murine and human fertility through a pancreas-bone-testis axis. J Clin Invest. 2013 Jun; 123(6):2421-33.
Score: 0.008
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Falkard B, Kumar TR, Hecht LS, Matthews KA, Henrich PP, Gulati S, Lewis RE, Manary MJ, Winzeler EA, Sinnis P, Prigge ST, Heussler V, Deschermeier C, Fidock D. A key role for lipoic acid synthesis during Plasmodium liver stage development. Cell Microbiol. 2013 Sep; 15(9):1585-604.
Score: 0.008
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Anderson JW, Sarantakis D, Terpinski J, Kumar TR, Tsai HC, Kuo M, Ager AL, Jacobs WR, Schiehser GA, Ekins S, Sacchettini JC, Jacobus DP, Fidock DA, Freundlich JS. Novel diaryl ureas with efficacy in a mouse model of malaria. Bioorg Med Chem Lett. 2013 Feb 15; 23(4):1022-5.
Score: 0.007
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Panneerdoss S, Chang YF, Buddavarapu KC, Chen HI, Shetty G, Wang H, Chen Y, Kumar TR, Rao MK. Androgen-responsive microRNAs in mouse Sertoli cells. PLoS One. 2012; 7(7):e41146.
Score: 0.007
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Kumar TR, Fairchild-Huntress V, Low MJ. Gonadotrope-specific expression of the human follicle-stimulating hormone beta-subunit gene in pituitaries of transgenic mice. Mol Endocrinol. 1992 Jan; 6(1):81-90.
Score: 0.007
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Baschong W, Wittlin S, Inglis KA, Fairlamb AH, Croft SL, Kumar TR, Fidock DA, Brun R. Triclosan is minimally effective in rodent malaria models. Nat Med. 2011 Jan; 17(1):33-4; author reply 34-5.
Score: 0.006
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Jimenez T, Sanchez G, McDermott JP, Nguyen AN, Kumar TR, Blanco G. Increased expression of the Na,K-ATPase alpha4 isoform enhances sperm motility in transgenic mice. Biol Reprod. 2011 Jan; 84(1):153-61.
Score: 0.006
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Yu M, Kumar TR, Nkrumah LJ, Coppi A, Retzlaff S, Li CD, Kelly BJ, Moura PA, Lakshmanan V, Freundlich JS, Valderramos JC, Vilcheze C, Siedner M, Tsai JH, Falkard B, Sidhu AB, Purcell LA, Gratraud P, Kremer L, Waters AP, Schiehser G, Jacobus DP, Janse CJ, Ager A, Jacobs WR, Sacchettini JC, Heussler V, Sinnis P, Fidock DA. The fatty acid biosynthesis enzyme FabI plays a key role in the development of liver-stage malarial parasites. Cell Host Microbe. 2008 Dec 11; 4(6):567-78.
Score: 0.006
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Gerin I, Louis GW, Zhang X, Prestwich TC, Kumar TR, Myers MG, Macdougald OA, Nothnick WB. Hyperphagia and obesity in female mice lacking tissue inhibitor of metalloproteinase-1. Endocrinology. 2009 Apr; 150(4):1697-704.
Score: 0.006
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Nagaraja AK, Agno JE, Kumar TR, Matzuk MM. Luteinizing hormone promotes gonadal tumorigenesis in inhibin-deficient mice. Mol Cell Endocrinol. 2008 Nov 06; 294(1-2):19-28.
Score: 0.005
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Pangas SA, Jorgez CJ, Tran M, Agno J, Li X, Brown CW, Kumar TR, Matzuk MM. Intraovarian activins are required for female fertility. Mol Endocrinol. 2007 Oct; 21(10):2458-71.
Score: 0.005
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Iqbal J, Sun L, Kumar TR, Blair HC, Zaidi M. Follicle-stimulating hormone stimulates TNF production from immune cells to enhance osteoblast and osteoclast formation. Proc Natl Acad Sci U S A. 2006 Oct 03; 103(40):14925-30.
Score: 0.005
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Nannenga B, Lu X, Dumble M, Van Maanen M, Nguyen TA, Sutton R, Kumar TR, Donehower LA. Augmented cancer resistance and DNA damage response phenotypes in PPM1D null mice. Mol Carcinog. 2006 Aug; 45(8):594-604.
Score: 0.005
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Sun L, Peng Y, Sharrow AC, Iqbal J, Zhang Z, Papachristou DJ, Zaidi S, Zhu LL, Yaroslavskiy BB, Zhou H, Zallone A, Sairam MR, Kumar TR, Bo W, Braun J, Cardoso-Landa L, Schaffler MB, Moonga BS, Blair HC, Zaidi M. FSH directly regulates bone mass. Cell. 2006 Apr 21; 125(2):247-60.
Score: 0.005
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Shetty G, Weng CC, Porter KL, Zhang Z, Pakarinen P, Kumar TR, Meistrich ML. Spermatogonial differentiation in juvenile spermatogonial depletion (jsd) mice with androgen receptor or follicle-stimulating hormone mutations. Endocrinology. 2006 Jul; 147(7):3563-70.
Score: 0.005
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Jablonka-Shariff A, Kumar TR, Eklund J, Comstock A, Boime I. Single-chain, triple-domain gonadotropin analogs with disulfide bond mutations in the alpha-subunit elicit dual follitropin and lutropin activities in vivo. Mol Endocrinol. 2006 Jun; 20(6):1437-46.
Score: 0.005
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Combelles CM, Carabatsos MJ, Kumar TR, Matzuk MM, Albertini DF. Hormonal control of somatic cell oocyte interactions during ovarian follicle development. Mol Reprod Dev. 2004 Nov; 69(3):347-55.
Score: 0.004
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Hirst RC, Abel MH, Wilkins V, Simpson C, Knight PG, Zhang FP, Huhtaniemi I, Kumar TR, Charlton HM. Influence of mutations affecting gonadotropin production or responsiveness on expression of inhibin subunit mRNA and protein in the mouse ovary. Reproduction. 2004 Jul; 128(1):43-52.
Score: 0.004
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Johnston H, Baker PJ, Abel M, Charlton HM, Jackson G, Fleming L, Kumar TR, O'Shaughnessy PJ. Regulation of Sertoli cell number and activity by follicle-stimulating hormone and androgen during postnatal development in the mouse. Endocrinology. 2004 Jan; 145(1):318-29.
Score: 0.004
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Abel MH, Huhtaniemi I, Pakarinen P, Kumar TR, Charlton HM. Age-related uterine and ovarian hypertrophy in FSH receptor knockout and FSHbeta subunit knockout mice. Reproduction. 2003 Feb; 125(2):165-73.
Score: 0.004
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Lukas-Croisier C, Lasala C, Nicaud J, Bedecarrás P, Kumar TR, Dutertre M, Matzuk MM, Picard JY, Josso N, Rey R. Follicle-stimulating hormone increases testicular Anti-Mullerian hormone (AMH) production through sertoli cell proliferation and a nonclassical cyclic adenosine 5'-monophosphate-mediated activation of the AMH Gene. Mol Endocrinol. 2003 Apr; 17(4):550-61.
Score: 0.004
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Baker PJ, Pakarinen P, Huhtaniemi IT, Abel MH, Charlton HM, Kumar TR, O'Shaughnessy PJ. Failure of normal Leydig cell development in follicle-stimulating hormone (FSH) receptor-deficient mice, but not FSHbeta-deficient mice: role for constitutive FSH receptor activity. Endocrinology. 2003 Jan; 144(1):138-45.
Score: 0.004
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Durlinger AL, Gruijters MJ, Kramer P, Karels B, Kumar TR, Matzuk MM, Rose UM, de Jong FH, Uilenbroek JT, Grootegoed JA, Themmen AP. Anti-Müllerian hormone attenuates the effects of FSH on follicle development in the mouse ovary. Endocrinology. 2001 Nov; 142(11):4891-9.
Score: 0.003
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Burns KH, Yan C, Kumar TR, Matzuk MM. Analysis of ovarian gene expression in follicle-stimulating hormone beta knockout mice. Endocrinology. 2001 Jul; 142(7):2742-51.
Score: 0.003
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Lau AL, Kumar TR, Nishimori K, Bonadio J, Matzuk MM. Activin betaC and betaE genes are not essential for mouse liver growth, differentiation, and regeneration. Mol Cell Biol. 2000 Aug; 20(16):6127-37.
Score: 0.003
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Cipriano SC, Chen L, Kumar TR, Matzuk MM. Follistatin is a modulator of gonadal tumor progression and the activin-induced wasting syndrome in inhibin-deficient mice. Endocrinology. 2000 Jul; 141(7):2319-27.
Score: 0.003
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Jhaveri S, Erzurumlu RS, Chiaia N, Kumar TR, Matzuk MM. Defective whisker follicles and altered brainstem patterns in activin and follistatin knockout mice. Mol Cell Neurosci. 1998 Nov; 12(4-5):206-19.
Score: 0.003
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Matzuk MM, Dionne L, Guo Q, Kumar TR, Lebovitz RM. Ovarian function in superoxide dismutase 1 and 2 knockout mice. Endocrinology. 1998 Sep; 139(9):4008-11.
Score: 0.003
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Guo Q, Kumar TR, Woodruff T, Hadsell LA, DeMayo FJ, Matzuk MM. Overexpression of mouse follistatin causes reproductive defects in transgenic mice. Mol Endocrinol. 1998 Jan; 12(1):96-106.
Score: 0.003
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Palapattu GS, Bao S, Kumar TR, Matzuk MM. Transgenic mouse models for tumor suppressor genes. Cancer Detect Prev. 1998; 22(1):75-86.
Score: 0.003
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Zhou J, Kumar TR, Matzuk MM, Bondy C. Insulin-like growth factor I regulates gonadotropin responsiveness in the murine ovary. Mol Endocrinol. 1997 Dec; 11(13):1924-33.
Score: 0.003
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Dong J, Albertini DF, Nishimori K, Kumar TR, Lu N, Matzuk MM. Growth differentiation factor-9 is required during early ovarian folliculogenesis. Nature. 1996 Oct 10; 383(6600):531-5.
Score: 0.002
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Matzuk MM, Kumar TR, Shou W, Coerver KA, Lau AL, Behringer RR, Finegold MJ. Transgenic models to study the roles of inhibins and activins in reproduction, oncogenesis, and development. Recent Prog Horm Res. 1996; 51:123-54; discussion 155-7.
Score: 0.002
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Matzuk MM, Kumar TR, Vassalli A, Bickenbach JR, Roop DR, Jaenisch R, Bradley A. Functional analysis of activins during mammalian development. Nature. 1995 Mar 23; 374(6520):354-6.
Score: 0.002
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Matzuk MM, Kumar TR, Bradley A. Different phenotypes for mice deficient in either activins or activin receptor type II. Nature. 1995 Mar 23; 374(6520):356-60.
Score: 0.002
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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