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Connection

David Riches to Mice

This is a "connection" page, showing publications David Riches has written about Mice.

 
Connection Strength
 
 
 
1.091
 
  1. Redente EF, Song T, Javkhlan N, Edelman BL, Foster DG, Wilson JA, Chakraborty S, Cooley JC, Gaurav R, Saguthi S, Seibold MA, Blumhagen RZ, Schwartz DA, Yang IV, Matsuda J, Bridges JP, Zemans RL, Tuder RM, Riches DWH. Conditional BCL-2 Expression in Fibroblasts Promotes Persistent Pulmonary Fibrosis which is Reversible by Therapeutic BCL-2 Inhibition. Nat Commun. 2026 Feb 28; 17(1).
    View in: PubMed
    Score: 0.069
  2. Petrache I, Riches DW. Reduced Bik expression drives low-grade airway inflammation and increased risk for COPD in females. J Clin Invest. 2024 Feb 15; 134(4).
    View in: PubMed
    Score: 0.060
  3. Redente EF, Black BP, Backos DS, Bahadur AN, Humphries SM, Lynch DA, Tuder RM, Zemans RL, Riches DWH. Persistent, Progressive Pulmonary Fibrosis and Epithelial Remodeling in Mice. Am J Respir Cell Mol Biol. 2021 06; 64(6):669-676.
    View in: PubMed
    Score: 0.050
  4. Redente EF, Chakraborty S, Sajuthi S, Black BP, Edelman BL, Seibold MA, Riches DW. Loss of Fas signaling in fibroblasts impairs homeostatic fibrosis resolution and promotes persistent pulmonary fibrosis. JCI Insight. 2020 12 08; 6(1).
    View in: PubMed
    Score: 0.048
  5. Bamberg A, Redente EF, Groshong SD, Tuder RM, Cool CD, Keith RC, Edelman BL, Black BP, Cosgrove GP, Wynes MW, Curran-Everett D, De Langhe S, Ortiz LA, Thorburn A, Riches DWH. Protein Tyrosine Phosphatase-N13 Promotes Myofibroblast Resistance to Apoptosis in Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2018 10 01; 198(7):914-927.
    View in: PubMed
    Score: 0.041
  6. Redente EF, Aguilar MA, Black BP, Edelman BL, Bahadur AN, Humphries SM, Lynch DA, Wollin L, Riches DWH. Nintedanib reduces pulmonary fibrosis in a model of rheumatoid arthritis-associated interstitial lung disease. Am J Physiol Lung Cell Mol Physiol. 2018 06 01; 314(6):L998-L1009.
    View in: PubMed
    Score: 0.040
  7. Redente EF, Keith RC, Janssen W, Henson PM, Ortiz LA, Downey GP, Bratton DL, Riches DW. Tumor necrosis factor-a accelerates the resolution of established pulmonary fibrosis in mice by targeting profibrotic lung macrophages. Am J Respir Cell Mol Biol. 2014 Apr; 50(4):825-37.
    View in: PubMed
    Score: 0.030
  8. Keith RC, Sokolove J, Edelman BL, Lahey L, Redente EF, Holers VM, Sakaguchi S, Robinson WH, Riches DW. Testosterone is protective in the sexually dimorphic development of arthritis and lung disease in SKG mice. Arthritis Rheum. 2013 Jun; 65(6):1487-93.
    View in: PubMed
    Score: 0.029
  9. Keith RC, Powers JL, Redente EF, Sergew A, Martin RJ, Gizinski A, Holers VM, Sakaguchi S, Riches DW. A novel model of rheumatoid arthritis-associated interstitial lung disease in SKG mice. Exp Lung Res. 2012 Mar; 38(2):55-66.
    View in: PubMed
    Score: 0.026
  10. Redente EF, Jacobsen KM, Solomon JJ, Lara AR, Faubel S, Keith RC, Henson PM, Downey GP, Riches DW. Age and sex dimorphisms contribute to the severity of bleomycin-induced lung injury and fibrosis. Am J Physiol Lung Cell Mol Physiol. 2011 Oct; 301(4):L510-8.
    View in: PubMed
    Score: 0.025
  11. Wynes MW, Edelman BL, Kostyk AG, Edwards MG, Coldren C, Groshong SD, Cosgrove GP, Redente EF, Bamberg A, Brown KK, Reisdorph N, Keith RC, Frankel SK, Riches DW. Increased cell surface Fas expression is necessary and sufficient to sensitize lung fibroblasts to Fas ligation-induced apoptosis: implications for fibroblast accumulation in idiopathic pulmonary fibrosis. J Immunol. 2011 Jul 01; 187(1):527-37.
    View in: PubMed
    Score: 0.025
  12. Cooley JC, Penick SK, Wilson JA, Javkhlan N, Foster DG, Edelman BL, Schott CA, Humphries SM, Lynch DA, Schwartz DA, Riches DWH, Redente EF. Nintedanib increases BCL-2 in fibrotic fibroblasts, enhancing ABT-199 apoptosis and fibrosis resolution. Am J Respir Cell Mol Biol. 2026 Aug 01; 74(8):1103-1113.
    View in: PubMed
    Score: 0.018
  13. Soond SM, Terry JL, Riches DW. TRUSS, a tumor necrosis factor receptor-1-interacting protein, activates c-Jun NH(2)-terminal kinase and transcription factor AP-1. FEBS Lett. 2006 Aug 21; 580(19):4591-6.
    View in: PubMed
    Score: 0.018
  14. Kostyk AG, Dahl KM, Wynes MW, Whittaker LA, Weiss DJ, Loi R, Riches DW. Regulation of chemokine expression by NaCl occurs independently of cystic fibrosis transmembrane conductance regulator in macrophages. Am J Pathol. 2006 Jul; 169(1):12-20.
    View in: PubMed
    Score: 0.018
  15. Foster DG, Javkhlan N, Black BP, Vestal BE, Riches DW, Redente EF. Pulmonary fibroblast subsets demonstrate differentially enriched signaling pathways during fibrosis resolution and repair. JCI Insight. 2026 Jul 08; 11(13).
    View in: PubMed
    Score: 0.018
  16. Van Linden AA, Cottin V, Frankel SK, Riches DW. Hierarchical phosphorylation of the TNF-alpha receptor, TNF-R1, by p42Mapk/Erk at basic Pro-directed kinase sites. Biochemistry. 2005 May 10; 44(18):6980-9.
    View in: PubMed
    Score: 0.016
  17. Wynes MW, Riches DW. Transcription of macrophage IGF-I exon 1 is positively regulated by the 5'-untranslated region and negatively regulated by the 5'-flanking region. Am J Physiol Lung Cell Mol Physiol. 2005 Jun; 288(6):L1089-98.
    View in: PubMed
    Score: 0.016
  18. Frankel SK, Moats-Staats BM, Cool CD, Wynes MW, Stiles AD, Riches DW. Human insulin-like growth factor-IA expression in transgenic mice promotes adenomatous hyperplasia but not pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol. 2005 May; 288(5):L805-12.
    View in: PubMed
    Score: 0.016
  19. Wynes MW, Frankel SK, Riches DW. IL-4-induced macrophage-derived IGF-I protects myofibroblasts from apoptosis following growth factor withdrawal. J Leukoc Biol. 2004 Nov; 76(5):1019-27.
    View in: PubMed
    Score: 0.016
  20. Doan JE, Windmiller DA, Riches DW. Differential regulation of TNF-R1 signaling: lipid raft dependency of p42mapk/erk2 activation, but not NF-kappaB activation. J Immunol. 2004 Jun 15; 172(12):7654-60.
    View in: PubMed
    Score: 0.015
  21. Wang F, Ting C, Riemondy KA, Douglas M, Foster K, Patel N, Kaku N, Linsalata A, Nemzek J, Varisco BM, Cohen E, Wilson JA, Riches DW, Redente EF, Toivola DM, Zhou X, Moore BB, Coulombe PA, Omary MB, Zemans RL. Regulation of epithelial transitional states in murine and human pulmonary fibrosis. J Clin Invest. 2023 11 15; 133(22).
    View in: PubMed
    Score: 0.015
  22. Soond SM, Terry JL, Colbert JD, Riches DW. TRUSS, a novel tumor necrosis factor receptor 1 scaffolding protein that mediates activation of the transcription factor NF-kappaB. Mol Cell Biol. 2003 Nov; 23(22):8334-44.
    View in: PubMed
    Score: 0.015
  23. Wynes MW, Riches DW. Induction of macrophage insulin-like growth factor-I expression by the Th2 cytokines IL-4 and IL-13. J Immunol. 2003 Oct 01; 171(7):3550-9.
    View in: PubMed
    Score: 0.015
  24. Cooley JC, Javkhlan N, Wilson JA, Foster DG, Edelman BL, Ortiz LA, Schwartz DA, Riches DW, Redente EF. Inhibition of antiapoptotic BCL-2 proteins with ABT-263 induces fibroblast apoptosis, reversing persistent pulmonary fibrosis. JCI Insight. 2023 02 08; 8(3).
    View in: PubMed
    Score: 0.014
  25. Caracena T, Blomberg R, Hewawasam RS, Fry ZE, Riches DWH, Magin CM. Alveolar epithelial cells and microenvironmental stiffness synergistically drive fibroblast activation in three-dimensional hydrogel lung models. Biomater Sci. 2022 Dec 06; 10(24):7133-7148.
    View in: PubMed
    Score: 0.014
  26. Kerby GS, Cottin V, Accurso FJ, Hoffmann F, Chan ED, Fadok VA, Riches DW. Impairment of macrophage survival by NaCl: implications for early pulmonary inflammation in cystic fibrosis. Am J Physiol Lung Cell Mol Physiol. 2002 Jul; 283(1):L188-97.
    View in: PubMed
    Score: 0.013
  27. Chan ED, Morris KR, Belisle JT, Hill P, Remigio LK, Brennan PJ, Riches DW. Induction of inducible nitric oxide synthase-NO* by lipoarabinomannan of Mycobacterium tuberculosis is mediated by MEK1-ERK, MKK7-JNK, and NF-kappaB signaling pathways. Infect Immun. 2001 Apr; 69(4):2001-10.
    View in: PubMed
    Score: 0.012
  28. Chan ED, Riches DW. IFN-gamma + LPS induction of iNOS is modulated by ERK, JNK/SAPK, and p38(mapk) in a mouse macrophage cell line. Am J Physiol Cell Physiol. 2001 Mar; 280(3):C441-50.
    View in: PubMed
    Score: 0.012
  29. Aschner Y, Nelson M, Brenner M, Roybal H, Beke K, Meador C, Foster D, Correll KA, Reynolds PR, Anderson K, Redente EF, Matsuda J, Riches DWH, Groshong SD, Pozzi A, Sap J, Wang Q, Rajshankar D, McCulloch CAG, Zemans RL, Downey GP. Protein tyrosine phosphatase-a amplifies transforming growth factor-ß-dependent profibrotic signaling in lung fibroblasts. Am J Physiol Lung Cell Mol Physiol. 2020 08 01; 319(2):L294-L311.
    View in: PubMed
    Score: 0.012
  30. Van Linden AA, Cottin V, Leu C, Riches DW. Phosphorylation of the membrane proximal region of tumor necrosis factor receptor CD120a (p55) at ERK consensus sites. J Biol Chem. 2000 Mar 10; 275(10):6996-7003.
    View in: PubMed
    Score: 0.011
  31. Uh S, Van Linden A, Riches DW. Phosphorylation of 130- and 95-kDa substrates associated with tumor necrosis factor-alpha receptor CD120a (p55). J Biol Chem. 2000 Jan 14; 275(2):793-800.
    View in: PubMed
    Score: 0.011
  32. Cottin V, Van Linden A, Riches DW. Phosphorylation of tumor necrosis factor receptor CD120a (p55) by p42(mapk/erk2) induces changes in its subcellular localization. J Biol Chem. 1999 Nov 12; 274(46):32975-87.
    View in: PubMed
    Score: 0.011
  33. Wollin L, Distler JHW, Redente EF, Riches DWH, Stowasser S, Schlenker-Herceg R, Maher TM, Kolb M. Potential of nintedanib in treatment of progressive fibrosing interstitial lung diseases. Eur Respir J. 2019 09; 54(3).
    View in: PubMed
    Score: 0.011
  34. Chan ED, Winston BW, Uh ST, Remigio LK, Riches DW. Systematic evaluation of the mitogen-activated protein kinases in the induction of iNOS by tumor necrosis factor-alpha and interferon-gamma. Chest. 1999 Jul; 116(1 Suppl):91S-92S.
    View in: PubMed
    Score: 0.011
  35. Sable CL, Riches DW. Cloning and functional activity of a novel truncated form of annexin IV in mouse macrophages. Biochem Biophys Res Commun. 1999 Apr 29; 258(1):162-7.
    View in: PubMed
    Score: 0.011
  36. Chan ED, Winston BW, Uh ST, Wynes MW, Rose DM, Riches DW. Evaluation of the role of mitogen-activated protein kinases in the expression of inducible nitric oxide synthase by IFN-gamma and TNF-alpha in mouse macrophages. J Immunol. 1999 Jan 01; 162(1):415-22.
    View in: PubMed
    Score: 0.011
  37. Chan ED, Riches DW. Potential role of the JNK/SAPK signal transduction pathway in the induction of iNOS by TNF-alpha. Biochem Biophys Res Commun. 1998 Dec 30; 253(3):790-6.
    View in: PubMed
    Score: 0.011
  38. Riches DW, Chan ED, Zahradka EA, Winston BW, Remigio LK, Lake FR. Cooperative signaling by tumor necrosis factor receptors CD120a (p55) and CD120b (p75) in the expression of nitric oxide and inducible nitric oxide synthase by mouse macrophages. J Biol Chem. 1998 Aug 28; 273(35):22800-6.
    View in: PubMed
    Score: 0.010
  39. Chan ED, Winston BW, Jarpe MB, Wynes MW, Riches DW. Preferential activation of the p46 isoform of JNK/SAPK in mouse macrophages by TNF alpha. Proc Natl Acad Sci U S A. 1997 Nov 25; 94(24):13169-74.
    View in: PubMed
    Score: 0.010
  40. Winston BW, Chan ED, Johnson GL, Riches DW. Activation of p38mapk, MKK3, and MKK4 by TNF-alpha in mouse bone marrow-derived macrophages. J Immunol. 1997 Nov 01; 159(9):4491-7.
    View in: PubMed
    Score: 0.010
  41. McClendon J, Jansing NL, Redente EF, Gandjeva A, Ito Y, Colgan SP, Ahmad A, Riches DWH, Chapman HA, Mason RJ, Tuder RM, Zemans RL. Hypoxia-Inducible Factor 1a Signaling Promotes Repair of the Alveolar Epithelium after Acute Lung Injury. Am J Pathol. 2017 Aug; 187(8):1772-1786.
    View in: PubMed
    Score: 0.009
  42. Winston BW, Remigio LK, Riches DW. Preferential involvement of MEK1 in the tumor necrosis factor-alpha-induced activation of p42mapk/erk2 in mouse macrophages. J Biol Chem. 1995 Nov 17; 270(46):27391-4.
    View in: PubMed
    Score: 0.008
  43. Phinney DG, Di Giuseppe M, Njah J, Sala E, Shiva S, St Croix CM, Stolz DB, Watkins SC, Di YP, Leikauf GD, Kolls J, Riches DW, Deiuliis G, Kaminski N, Boregowda SV, McKenna DH, Ortiz LA. Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle microRNAs. Nat Commun. 2015 Oct 07; 6:8472.
    View in: PubMed
    Score: 0.008
  44. Winston BW, Riches DW. Activation of p42mapk/erk2 following engagement of tumor necrosis factor receptor CD120a (p55) in mouse macrophages. J Immunol. 1995 Aug 01; 155(3):1525-33.
    View in: PubMed
    Score: 0.008
  45. Winston BW, Lange-Carter CA, Gardner AM, Johnson GL, Riches DW. Tumor necrosis factor alpha rapidly activates the mitogen-activated protein kinase (MAPK) cascade in a MAPK kinase kinase-dependent, c-Raf-1-independent fashion in mouse macrophages. Proc Natl Acad Sci U S A. 1995 Feb 28; 92(5):1614-8.
    View in: PubMed
    Score: 0.008
  46. Lake FR, Noble PW, Henson PM, Riches DW. Functional switching of macrophage responses to tumor necrosis factor-alpha (TNF alpha) by interferons. Implications for the pleiotropic activities of TNF alpha. J Clin Invest. 1994 Apr; 93(4):1661-9.
    View in: PubMed
    Score: 0.008
  47. Aschner Y, Khalifah AP, Briones N, Yamashita C, Dolgonos L, Young SK, Campbell MN, Riches DW, Redente EF, Janssen WJ, Henson PM, Sap J, Vacaresse N, Kapus A, McCulloch CA, Zemans RL, Downey GP. Protein tyrosine phosphatase a mediates profibrotic signaling in lung fibroblasts through TGF-ß responsiveness. Am J Pathol. 2014 May; 184(5):1489-502.
    View in: PubMed
    Score: 0.008
  48. Lake FR, Dempsey EC, Spahn JD, Riches DW. Involvement of protein kinase C in macrophage activation by poly(I.C). Am J Physiol. 1994 Jan; 266(1 Pt 1):C134-42.
    View in: PubMed
    Score: 0.007
  49. Jakubzick C, Gautier EL, Gibbings SL, Sojka DK, Schlitzer A, Johnson TE, Ivanov S, Duan Q, Bala S, Condon T, van Rooijen N, Grainger JR, Belkaid Y, Ma'ayan A, Riches DW, Yokoyama WM, Ginhoux F, Henson PM, Randolph GJ. Minimal differentiation of classical monocytes as they survey steady-state tissues and transport antigen to lymph nodes. Immunity. 2013 Sep 19; 39(3):599-610.
    View in: PubMed
    Score: 0.007
  50. Laszlo DJ, Henson PM, Remigio LK, Weinstein L, Sable C, Noble PW, Riches DW. Development of functional diversity in mouse macrophages. Mutual exclusion of two phenotypic states. Am J Pathol. 1993 Aug; 143(2):587-97.
    View in: PubMed
    Score: 0.007
  51. Noble PW, Henson PM, Lucas C, Mora-Worms M, Carré PC, Riches DW. Transforming growth factor-beta primes macrophages to express inflammatory gene products in response to particulate stimuli by an autocrine/paracrine mechanism. J Immunol. 1993 Jul 15; 151(2):979-89.
    View in: PubMed
    Score: 0.007
  52. Noble PW, Lake FR, Henson PM, Riches DW. Hyaluronate activation of CD44 induces insulin-like growth factor-1 expression by a tumor necrosis factor-alpha-dependent mechanism in murine macrophages. J Clin Invest. 1993 Jun; 91(6):2368-77.
    View in: PubMed
    Score: 0.007
  53. Trivedi R, Redente EF, Thakur A, Riches DW, Kompella UB. Local delivery of biodegradable pirfenidone nanoparticles ameliorates bleomycin-induced pulmonary fibrosis in mice. Nanotechnology. 2012 Dec 21; 23(50):505101.
    View in: PubMed
    Score: 0.007
  54. Rayamajhi M, Delgado C, Condon TV, Riches DW, Lenz LL. Lung B cells promote early pathogen dissemination and hasten death from inhalation anthrax. Mucosal Immunol. 2012 Jul; 5(4):444-54.
    View in: PubMed
    Score: 0.007
  55. Underwood GA, Riches DW. Transmembrane-mediated changes in [Ca2+] are involved in the signaling pathway leading to macrophage cytocidal differentiation: implications of localized changes in intracellular [Ca2+] and of interferon priming on Ca2+ utilization. Mol Biol Cell. 1992 Mar; 3(3):335-47.
    View in: PubMed
    Score: 0.007
  56. De Arras L, Yang IV, Lackford B, Riches DW, Prekeris R, Freedman JH, Schwartz DA, Alper S. Spatiotemporal inhibition of innate immunity signaling by the Tbc1d23 RAB-GAP. J Immunol. 2012 Mar 15; 188(6):2905-13.
    View in: PubMed
    Score: 0.007
  57. Zhang Y, Leung DY, Richers BN, Liu Y, Remigio LK, Riches DW, Goleva E. Vitamin D inhibits monocyte/macrophage proinflammatory cytokine production by targeting MAPK phosphatase-1. J Immunol. 2012 Mar 01; 188(5):2127-35.
    View in: PubMed
    Score: 0.007
  58. Riches DW, Underwood GA. Expression of interferon-beta during the triggering phase of macrophage cytocidal activation. Evidence for an autocrine/paracrine role in the regulation of this state. J Biol Chem. 1991 Dec 25; 266(36):24785-92.
    View in: PubMed
    Score: 0.006
  59. Yamashita CM, Dolgonos L, Zemans RL, Young SK, Robertson J, Briones N, Suzuki T, Campbell MN, Gauldie J, Radisky DC, Riches DW, Yu G, Kaminski N, McCulloch CA, Downey GP. Matrix metalloproteinase 3 is a mediator of pulmonary fibrosis. Am J Pathol. 2011 Oct; 179(4):1733-45.
    View in: PubMed
    Score: 0.006
  60. Roberson EC, Tully JE, Guala AS, Reiss JN, Godburn KE, Pociask DA, Alcorn JF, Riches DW, Dienz O, Janssen-Heininger YM, Anathy V. Influenza induces endoplasmic reticulum stress, caspase-12-dependent apoptosis, and c-Jun N-terminal kinase-mediated transforming growth factor-ß release in lung epithelial cells. Am J Respir Cell Mol Biol. 2012 May; 46(5):573-81.
    View in: PubMed
    Score: 0.006
  61. Rayamajhi M, Redente EF, Condon TV, Gonzalez-Juarrero M, Riches DW, Lenz LL. Non-surgical intratracheal instillation of mice with analysis of lungs and lung draining lymph nodes by flow cytometry. J Vis Exp. 2011 May 02; (51).
    View in: PubMed
    Score: 0.006
  62. Noble PW, Henson PM, Riches DW. Insulin-like growth factor-1 (IGF-1) mRNA expression in bone marrow derived macrophages is stimulated by chrysotile asbestos and bleomycin. A potential marker for a reparative macrophage phenotype. Chest. 1991 Mar; 99(3 Suppl):79S-80S.
    View in: PubMed
    Score: 0.006
  63. Lew DB, Leslie CC, Henson PM, Riches DW. Role of endogenously derived leukotrienes in the regulation of lysosomal enzyme expression in macrophages exposed to beta 1,3-glucan. J Leukoc Biol. 1991 Mar; 49(3):266-76.
    View in: PubMed
    Score: 0.006
  64. De Whalley CV, Riches DW. Influence of the cytocidal macrophage phenotype on the degradation of acetylated low density lipoproteins: dual regulation of scavenger receptor activity and of intracellular degradation of endocytosed ligand. Exp Cell Res. 1991 Feb; 192(2):460-8.
    View in: PubMed
    Score: 0.006
  65. Tollefson AK, Oberley-Deegan RE, Butterfield KT, Nicks ME, Weaver MR, Remigio LK, Decsesznak J, Chu HW, Bratton DL, Riches DW, Bowler RP. Endogenous enzymes (NOX and ECSOD) regulate smoke-induced oxidative stress. Free Radic Biol Med. 2010 Dec 15; 49(12):1937-46.
    View in: PubMed
    Score: 0.006
  66. Fernandez-Boyanapalli R, McPhillips KA, Frasch SC, Janssen WJ, Dinauer MC, Riches DW, Henson PM, Byrne A, Bratton DL. Impaired phagocytosis of apoptotic cells by macrophages in chronic granulomatous disease is reversed by IFN-? in a nitric oxide-dependent manner. J Immunol. 2010 Oct 01; 185(7):4030-41.
    View in: PubMed
    Score: 0.006
  67. Fernandez-Boyanapalli R, Frasch SC, Riches DW, Vandivier RW, Henson PM, Bratton DL. PPAR? activation normalizes resolution of acute sterile inflammation in murine chronic granulomatous disease. Blood. 2010 Nov 25; 116(22):4512-22.
    View in: PubMed
    Score: 0.006
  68. Graham BB, Mentink-Kane MM, El-Haddad H, Purnell S, Zhang L, Zaiman A, Redente EF, Riches DW, Hassoun PM, Bandeira A, Champion HC, Butrous G, Wynn TA, Tuder RM. Schistosomiasis-induced experimental pulmonary hypertension: role of interleukin-13 signaling. Am J Pathol. 2010 Sep; 177(3):1549-61.
    View in: PubMed
    Score: 0.006
  69. Redente EF, Dwyer-Nield LD, Barrett BS, Riches DW, Malkinson AM. Lung tumor growth is stimulated in IFN-gamma-/- mice and inhibited in IL-4Ralpha-/- mice. Anticancer Res. 2009 Dec; 29(12):5095-101.
    View in: PubMed
    Score: 0.006
  70. Honsho S, Nishikawa S, Amano K, Zen K, Adachi Y, Kishita E, Matsui A, Katsume A, Yamaguchi S, Nishikawa K, Isoda K, Riches DW, Matoba S, Okigaki M, Matsubara H. Pressure-mediated hypertrophy and mechanical stretch induces IL-1 release and subsequent IGF-1 generation to maintain compensative hypertrophy by affecting Akt and JNK pathways. Circ Res. 2009 Nov 20; 105(11):1149-58.
    View in: PubMed
    Score: 0.006
  71. Vandivier RW, Richens TR, Horstmann SA, deCathelineau AM, Ghosh M, Reynolds SD, Xiao YQ, Riches DW, Plumb J, Vachon E, Downey GP, Henson PM. Dysfunctional cystic fibrosis transmembrane conductance regulator inhibits phagocytosis of apoptotic cells with proinflammatory consequences. Am J Physiol Lung Cell Mol Physiol. 2009 Oct; 297(4):L677-86.
    View in: PubMed
    Score: 0.005
  72. Fernandez-Boyanapalli RF, Frasch SC, McPhillips K, Vandivier RW, Harry BL, Riches DW, Henson PM, Bratton DL. Impaired apoptotic cell clearance in CGD due to altered macrophage programming is reversed by phosphatidylserine-dependent production of IL-4. Blood. 2009 Feb 26; 113(9):2047-55.
    View in: PubMed
    Score: 0.005
  73. Riches DW, Henson PM, Remigio LK, Catterall JF, Strunk RC. Differential regulation of gene expression during macrophage activation with a polyribonucleotide. The role of endogenously derived IFN. J Immunol. 1988 Jul 01; 141(1):180-8.
    View in: PubMed
    Score: 0.005
  74. Riches DW, Henson PM. Functional aspects of mononuclear phagocyte involvement in lung inflammation. Ann N Y Acad Sci. 1986; 465:6-14.
    View in: PubMed
    Score: 0.004
  75. Riches DW, Watkins JL, Henson PM, Stanworth DR. Regulation of macrophage lysosomal secretion by adenosine, adenosine phosphate esters, and related structural analogues of adenosine. J Leukoc Biol. 1985 May; 37(5):545-57.
    View in: PubMed
    Score: 0.004
  76. Abell AN, DeCathelineau AM, Weed SA, Ambruso DR, Riches DW, Johnson GL. Rac2D57N, a dominant inhibitory Rac2 mutant that inhibits p38 kinase signaling and prevents surface ruffling in bone-marrow-derived macrophages. J Cell Sci. 2004 Jan 15; 117(Pt 2):243-55.
    View in: PubMed
    Score: 0.004
  77. Gambelli F, Di P, Niu X, Friedman M, Hammond T, Riches DW, Ortiz LA. Phosphorylation of tumor necrosis factor receptor 1 (p55) protects macrophages from silica-induced apoptosis. J Biol Chem. 2004 Jan 16; 279(3):2020-9.
    View in: PubMed
    Score: 0.004
  78. Chan ED, Riches DW, White CW. Redox paradox: effect of N-acetylcysteine and serum on oxidation reduction-sensitive mitogen-activated protein kinase signaling pathways. Am J Respir Cell Mol Biol. 2001 May; 24(5):627-32.
    View in: PubMed
    Score: 0.003
  79. Crippen TL, Riches DW, Hyde DM. Differential regulation of the expression of cytokine-induced neutrophil chemoattractant by mouse macrophages. Pathobiology. 1998; 66(1):24-32.
    View in: PubMed
    Score: 0.002
  80. Rose DM, Winston BW, Chan ED, Riches DW, Henson PM. Interferon-gamma and transforming growth factor-beta modulate the activation of mitogen-activated protein kinases and tumor necrosis factor-alpha production induced by Fc gamma-receptor stimulation in murine macrophages. Biochem Biophys Res Commun. 1997 Sep 08; 238(1):256-60.
    View in: PubMed
    Score: 0.002
  81. Rose DM, Winston BW, Chan ED, Riches DW, Gerwins P, Johnson GL, Henson PM. Fc gamma receptor cross-linking activates p42, p38, and JNK/SAPK mitogen-activated protein kinases in murine macrophages: role for p42MAPK in Fc gamma receptor-stimulated TNF-alpha synthesis. J Immunol. 1997 Apr 01; 158(7):3433-8.
    View in: PubMed
    Score: 0.002
  82. Rose DM, Fadok VA, Riches DW, Clay KL, Henson PM. Autocrine/paracrine involvement of platelet-activating factor and transforming growth factor-beta in the induction of phosphatidylserine recognition by murine macrophages. J Immunol. 1995 Dec 15; 155(12):5819-25.
    View in: PubMed
    Score: 0.002
  83. Fournier T, Riches DW, Winston BW, Rose DM, Young SK, Noble PW, Lake FR, Henson PM. Divergence in macrophage insulin-like growth factor-I (IGF-I) synthesis induced by TNF-alpha and prostaglandin E2. J Immunol. 1995 Aug 15; 155(4):2123-33.
    View in: PubMed
    Score: 0.002
  84. Wenzel SE, Trudeau JB, Riches DW, Westcott JY, Henson PM. Peritoneal lavage fluid alters patterns of eicosanoid production in murine bone marrow-derived and peritoneal macrophages: dependency on inflammatory state of the peritoneum. Inflammation. 1993 Dec; 17(6):743-56.
    View in: PubMed
    Score: 0.002
  85. Fadok VA, Laszlo DJ, Noble PW, Weinstein L, Riches DW, Henson PM. Particle digestibility is required for induction of the phosphatidylserine recognition mechanism used by murine macrophages to phagocytose apoptotic cells. J Immunol. 1993 Oct 15; 151(8):4274-85.
    View in: PubMed
    Score: 0.002
  86. Fadok VA, Voelker DR, Campbell PA, Bratton DL, Cohen JJ, Noble PW, Riches DW, Henson PM. The ability to recognize phosphatidylserine on apoptotic cells is an inducible function in murine bone marrow-derived macrophages. Chest. 1993 Feb; 103(2 Suppl):102S.
    View in: PubMed
    Score: 0.002
  87. Lew DB, Leslie CC, Riches DW, Henson PM. Induction of macrophage lysosomal hydrolase synthesis and secretion by beta-1,3-glucan. Cell Immunol. 1986 Jul; 100(2):340-50.
    View in: PubMed
    Score: 0.001
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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