NiyunJinNiyun Jin39.74404140000000-104.838394500000009854Jin, Niyun303/671-2637Instructorprns:coAuthorOfcoauthor ofprns:emailEncryptedemail addressFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:address2address line 2vivo:address3address line 3vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionvivo:hasResearchArearesearch areasvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsvivo:phoneNumberphonePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson13001 East 17th Place2SOMSchool of Medicine13001 East 17th PlaceAurora80045-2570CO2.141160.00703615144research areas1.222620.034474712coauthor of21.74132.8972760similar to1128selected publicationsAuthorship 1237913Authorship 1237924Authorship 1237961Authorship 1237973Authorship 1238002Authorship 1238013Authorship 1238033Authorship 1238043Authorship 1238051Authorship 1238061Authorship 1238083Authorship 1238097Authorship 1238132Authorship 1238162Authorship 1238194Authorship 1238212Authorship 1238283Authorship 1238353Authorship 123847318840468Hahn YS, Ji XY, Woo SI, Choi YK, Song MS, Shin KS, Jin N, O'Brien RL, Born WKImmunology lettersHahn YS, Ji XY, Woo SI, Choi YK, Song MS, Shin KS, Jin N, O'Brien RL, Born WK. V?1+ ?d T cells reduce IL-10-producing CD4+CD25+ T cells in the lung of ovalbumin-sensitized and challenged mice. Immunol Lett. 2008 Dec 22; 121(2):87-92.Immunol Lett2008-10-07T00:00:002008V?1+ ?d T cells reduce IL-10-producing CD4+CD25+ T cells in the lung of ovalbumin-sensitized and challenged mice.KimberlyDriscollKimberly A Driscoll39.74404140000000-104.8383945000000010494Driscoll, KimberlyAssoc Professor AdjointAuthorship 130361426317987Liu H, White J, Crawford F, Jin N, Ju X, Liu K, Jiang C, Marrack P, Zhang G, Kappler JWPloS oneLiu H, White J, Crawford F, Jin N, Ju X, Liu K, Jiang C, Marrack P, Zhang G, Kappler JW. A Rapid Method to Characterize Mouse IgG Antibodies and Isolate Native Antigen Binding IgG B Cell Hybridomas. PLoS One. 2015; 10(8):e0136613.PLoS One2015-08-28T00:00:002015A Rapid Method to Characterize Mouse IgG Antibodies and Isolate Native Antigen Binding IgG B Cell Hybridomas.Authorship 133533126453556Jin N, Wang Y, Crawford F, White J, Marrack P, Dai S, Kappler JWProceedings of the National Academy of Sciences of the United States of AmericaJin N, Wang Y, Crawford F, White J, Marrack P, Dai S, Kappler JW. N-terminal additions to the WE14 peptide of chromogranin A create strong autoantigen agonists in type 1 diabetes. Proc Natl Acad Sci U S A. 2015 Oct 27; 112(43):13318-23.Proc Natl Acad Sci U S A2015-10-09T00:00:002015N-terminal additions to the WE14 peptide of chromogranin A create strong autoantigen agonists in type 1 diabetes.Authorship 151298326550059Born WK, Roark CL, Jin N, Wands JM, Kemal Aydintug M, Huang Y, Chain JL, Hahn YS, Simonian PL, Fontenot AP, O'Brien RLThe open immunology journalBorn WK, Roark CL, Jin N, Wands JM, Kemal Aydintug M, Huang Y, Chain JL, Hahn YS, Simonian PL, Fontenot AP, O'Brien RL. Role of ?d T Cells in Lung Inflammation. Open Immunol J. 2009; 2:143-150.Open Immunol J2009-10-23T00:00:002009Role of ?d T Cells in Lung Inflammation.PatriciaGesualdoPatricia Dianne Gesualdo39.74404140000000-104.8383945000000012245Gesualdo, PatriciaResearch Senior InstructorShaodongDaiShaodong Dai39.74688660000000-104.8382567000000012302Dai, ShaodongProfessor12960345Hahn YS, Taube C, Jin N, Takeda K, Park JW, Wands JM, Aydintug MK, Roark CL, Lahn M, O'Brien RL, Gelfand EW, Born WKJournal of immunology (Baltimore, Md. : 1950)Hahn YS, Taube C, Jin N, Takeda K, Park JW, Wands JM, Aydintug MK, Roark CL, Lahn M, O'Brien RL, Gelfand EW, Born WK. V gamma 4+ gamma delta T cells regulate airway hyperreactivity to methacholine in ovalbumin-sensitized and challenged mice. J Immunol. 2003 Sep 15; 171(6):3170-8.J Immunol2003-09-15T00:00:002003V gamma 4+ gamma delta T cells regulate airway hyperreactivity to methacholine in ovalbumin-sensitized and challenged mice.1Professor3Asst Professor2Assoc Professor4Instructor15728474Jin N, Taube C, Sharp L, Hahn YS, Yin X, Wands JM, Roark CL, O'brien RL, Gelfand EW, Born WKJournal of immunology (Baltimore, Md. : 1950)Jin N, Taube C, Sharp L, Hahn YS, Yin X, Wands JM, Roark CL, O'brien RL, Gelfand EW, Born WK. Mismatched antigen prepares gamma delta T cells for suppression of airway hyperresponsiveness. J Immunol. 2005 Mar 01; 174(5):2671-9.J Immunol2005-03-01T00:00:002005Mismatched antigen prepares gamma delta T cells for suppression of airway hyperresponsiveness.16204632Wands JM, Roark CL, Aydintug MK, Jin N, Hahn YS, Cook L, Yin X, Dal Porto J, Lahn M, Hyde DM, Gelfand EW, Mason RJ, O'Brien RL, Born WKJournal of leukocyte biologyWands JM, Roark CL, Aydintug MK, Jin N, Hahn YS, Cook L, Yin X, Dal Porto J, Lahn M, Hyde DM, Gelfand EW, Mason RJ, O'Brien RL, Born WK. Distribution and leukocyte contacts of gammadelta T cells in the lung. J Leukoc Biol. 2005 Nov; 78(5):1086-96.J Leukoc Biol2005-10-04T00:00:002005Distribution and leukocyte contacts of gammadelta T cells in the lung.17333410Born WK, Jin N, Aydintug MK, Wands JM, French JD, Roark CL, O'Brien RLJournal of clinical immunologyBorn WK, Jin N, Aydintug MK, Wands JM, French JD, Roark CL, O'Brien RL. gammadelta T lymphocytes-selectable cells within the innate system? J Clin Immunol. 2007 Mar; 27(2):133-44.J Clin Immunol2007-02-14T00:00:002007gammadelta T lymphocytes-selectable cells within the innate system?17291280O'Brien RL, Roark CL, Jin N, Aydintug MK, French JD, Chain JL, Wands JM, Johnston M, Born WKImmunological reviewsO'Brien RL, Roark CL, Jin N, Aydintug MK, French JD, Chain JL, Wands JM, Johnston M, Born WK. gammadelta T-cell receptors: functional correlations. Immunol Rev. 2007 Feb; 215:77-88.Immunol Rev2007-02-01T00:00:002007gammadelta T-cell receptors: functional correlations.17709511Jin N, Miyahara N, Roark CL, French JD, Aydintug MK, Matsuda JL, Gapin L, O'Brien RL, Gelfand EW, Born WKJournal of immunology (Baltimore, Md. : 1950)Jin N, Miyahara N, Roark CL, French JD, Aydintug MK, Matsuda JL, Gapin L, O'Brien RL, Gelfand EW, Born WK. Airway hyperresponsiveness through synergy of gammadelta} T cells and NKT cells. J Immunol. 2007 Sep 01; 179(5):2961-8.J Immunol2007-09-01T00:00:002007Airway hyperresponsiveness through synergy of gammadelta} T cells and NKT cells.18927346Matsubara S, Takeda K, Jin N, Okamoto M, Matsuda H, Shiraishi Y, Park JW, McConville G, Joetham A, O'Brien RL, Dakhama A, Born WK, Gelfand EWAmerican journal of respiratory cell and molecular biologyMatsubara S, Takeda K, Jin N, Okamoto M, Matsuda H, Shiraishi Y, Park JW, McConville G, Joetham A, O'Brien RL, Dakhama A, Born WK, Gelfand EW. Vgamma1+ T cells and tumor necrosis factor-alpha in ozone-induced airway hyperresponsiveness. Am J Respir Cell Mol Biol. 2009 Apr; 40(4):454-63.Am J Respir Cell Mol Biol2008-10-16T00:00:002008Vgamma1+ T cells and tumor necrosis factor-alpha in ozone-induced airway hyperresponsiveness.19201853Jin N, Roark CL, Miyahara N, Taube C, Aydintug MK, Wands JM, Huang Y, Hahn YS, Gelfand EW, O'Brien RL, Born WKJournal of immunology (Baltimore, Md. : 1950)Jin N, Roark CL, Miyahara N, Taube C, Aydintug MK, Wands JM, Huang Y, Hahn YS, Gelfand EW, O'Brien RL, Born WK. Allergic airway hyperresponsiveness-enhancing gammadelta T cells develop in normal untreated mice and fail to produce IL-4/13, unlike Th2 and NKT cells. J Immunol. 2009 Feb 15; 182(4):2002-10.J Immunol2009-02-15T00:00:002009Allergic airway hyperresponsiveness-enhancing gammadelta T cells develop in normal untreated mice and fail to produce IL-4/13, unlike Th2 and NKT cells.19542369Huang Y, Jin N, Roark CL, Aydintug MK, Wands JM, Huang H, O'Brien RL, Born WKJournal of immunology (Baltimore, Md. : 1950)Huang Y, Jin N, Roark CL, Aydintug MK, Wands JM, Huang H, O'Brien RL, Born WK. The influence of IgE-enhancing and IgE-suppressive gammadelta T cells changes with exposure to inhaled ovalbumin. J Immunol. 2009 Jul 15; 183(2):849-55.J Immunol2009-06-19T00:00:002009The influence of IgE-enhancing and IgE-suppressive gammadelta T cells changes with exposure to inhaled ovalbumin.20152161O'Brien R, Jin N, Huang Y, Aydintug MK, Roark C, Born WImmunityO'Brien R, Jin N, Huang Y, Aydintug MK, Roark C, Born W. Characteristics of IL-17-producing gammadelta T cells. Immunity. 2010 Jan 29; 32(1):1; author reply 2-4.Immunity2010-01-29T00:00:002010Characteristics of IL-17-producing gammadelta T cells.20080388Zhang L, Jin N, Nakayama M, O'Brien RL, Eisenbarth GS, Born WKJournal of autoimmunityZhang L, Jin N, Nakayama M, O'Brien RL, Eisenbarth GS, Born WK. Gamma delta T cell receptors confer autonomous responsiveness to the insulin-peptide B:9-23. J Autoimmun. 2010 Jun; 34(4):478-84.J Autoimmun2010-01-18T00:00:002010Gamma delta T cell receptors confer autonomous responsiveness to the insulin-peptide B:9-23.21949373Crawford F, Stadinski B, Jin N, Michels A, Nakayama M, Pratt P, Marrack P, Eisenbarth G, Kappler JWProceedings of the National Academy of Sciences of the United States of AmericaCrawford F, Stadinski B, Jin N, Michels A, Nakayama M, Pratt P, Marrack P, Eisenbarth G, Kappler JW. Specificity and detection of insulin-reactive CD4+ T cells in type 1 diabetes in the nonobese diabetic (NOD) mouse. Proc Natl Acad Sci U S A. 2011 Oct 04; 108(40):16729-34.Proc Natl Acad Sci U S A2011-09-26T00:00:002011Specificity and detection of insulin-reactive CD4+ T cells in type 1 diabetes in the nonobese diabetic (NOD) mouse.22961659Roark CL, Huang Y, Jin N, Aydintug MK, Casper T, Sun D, Born WK, O'Brien RLImmunologic researchRoark CL, Huang Y, Jin N, Aydintug MK, Casper T, Sun D, Born WK, O'Brien RL. A canonical V?4Vd4+ ?d T cell population with distinct stimulation requirements which promotes the Th17 response. Immunol Res. 2013 Mar; 55(1-3):217-30.Immunol Res2013-03-01T00:00:002013A canonical V?4Vd4+ ?d T cell population with distinct stimulation requirements which promotes the Th17 response.23613928Macleod MK, David A, Jin N, Noges L, Wang J, Kappler JW, Marrack PPloS oneMacleod MK, David A, Jin N, Noges L, Wang J, Kappler JW, Marrack P. Influenza nucleoprotein delivered with aluminium salts protects mice from an influenza A virus that expresses an altered nucleoprotein sequence. PLoS One. 2013; 8(4):e61775.PLoS One2013-04-16T00:00:002013Influenza nucleoprotein delivered with aluminium salts protects mice from an influenza A virus that expresses an altered nucleoprotein sequence.14978091Hahn YS, Taube C, Jin N, Sharp L, Wands JM, Aydintug MK, Lahn M, Huber SA, O'Brien RL, Gelfand EW, Born WKJournal of immunology (Baltimore, Md. : 1950)Hahn YS, Taube C, Jin N, Sharp L, Wands JM, Aydintug MK, Lahn M, Huber SA, O'Brien RL, Gelfand EW, Born WK. Different potentials of gamma delta T cell subsets in regulating airway responsiveness: V gamma 1+ cells, but not V gamma 4+ cells, promote airway hyperreactivity, Th2 cytokines, and airway inflammation. J Immunol. 2004 Mar 01; 172(5):2894-902.J Immunol2004-03-01T00:00:002004Different potentials of gamma delta T cell subsets in regulating airway responsiveness: V gamma 1+ cells, but not V gamma 4+ cells, promote airway hyperreactivity, Th2 cytokines, and airway inflammation.18566396Cook L, Miyahara N, Jin N, Wands JM, Taube C, Roark CL, Potter TA, Gelfand EW, O'Brien RL, Born WKJournal of immunology (Baltimore, Md. : 1950)Cook L, Miyahara N, Jin N, Wands JM, Taube C, Roark CL, Potter TA, Gelfand EW, O'Brien RL, Born WK. Evidence that CD8+ dendritic cells enable the development of gammadelta T cells that modulate airway hyperresponsiveness. J Immunol. 2008 Jul 01; 181(1):309-19.J Immunol2008-07-01T00:00:002008Evidence that CD8+ dendritic cells enable the development of gammadelta T cells that modulate airway hyperresponsiveness.21553233Born WK, Zhang L, Nakayama M, Jin N, Chain JL, Huang Y, Aydintug MK, O'Brien RLCellular and molecular life sciences : CMLSBorn WK, Zhang L, Nakayama M, Jin N, Chain JL, Huang Y, Aydintug MK, O'Brien RL. Peptide antigens for gamma/delta T cells. Cell Mol Life Sci. 2011 Jul; 68(14):2335-43.Cell Mol Life Sci2011-05-08T00:00:002011Peptide antigens for gamma/delta T cells.Authorship 187406530165064Williams T, Krovi HS, Landry LG, Crawford F, Jin N, Hohenstein A, DeNicola ME, Michels AW, Davidson HW, Kent SC, Gapin L, Kappler JW, Nakayama MJournal of immunological methodsWilliams T, Krovi HS, Landry LG, Crawford F, Jin N, Hohenstein A, DeNicola ME, Michels AW, Davidson HW, Kent SC, Gapin L, Kappler JW, Nakayama M. Development of T cell lines sensitive to antigen stimulation. J Immunol Methods. 2018 11; 462:65-73.J Immunol Methods2018-08-28T00:00:002018Development of T cell lines sensitive to antigen stimulation.D001324Chemicals & Drugs1294070.785655AutoantigensLeslieBerg/O0TY7S51wjUKQ02eH7WjEJGV5IFBiK9DVE=Leslie Joan Berg39.74545800000000-104.8393691000000015151Berg, LeslieProfessorD010446Chemicals & Drugs3137150.715816Peptide FragmentsSOM-BDC AdultSOM-BDC Basic ResearchSOM-BDC Clinical Epi ResearchSOM-BDC PediatricAuthorship 198932630952805Wang Y, Sosinowski T, Novikov A, Crawford F, White J, Jin N, Liu Z, Zou J, Neau D, Davidson HW, Nakayama M, Kwok WW, Gapin L, Marrack P, Kappler JW, Dai SScience immunologyWang Y, Sosinowski T, Novikov A, Crawford F, White J, Jin N, Liu Z, Zou J, Neau D, Davidson HW, Nakayama M, Kwok WW, Gapin L, Marrack P, Kappler JW, Dai S. How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes. Sci Immunol. 2019 04 05; 4(34).Sci Immunol2019-04-05T00:00:002019How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes.D016176Concepts & Ideas1644090.813418T-Lymphocyte SubsetsSOM-IMM MICRO GENERAL OPERRuthStrockRuth Williamson Strock39.74404140000000-104.8383945000000015579Strock, RuthInstructorD012130Disorders42670.951056Respiratory HypersensitivityD016692Chemicals & Drugs391050.946862Receptors, Antigen, T-Cell, gamma-deltaSOM-MEDSOP-AdministrationClinical ImmunologyUniversity of Colorado Denver - Anschutz Medical CampusLaurentGapinLaurent Camille Gapin39.74545800000000-104.839369100000001822Gapin, LaurentProfessorMakiNakayamaMaki Nakayama39.74404140000000-104.838394500000001946Nakayama, MakiAssociate ProfessorPhilippaMarrackPhilippa Marrack39.74545800000000-104.839369100000002632Marrack, PhilippaDistinguished ProfessorChristinaRoarkChristina Lee Roark39.74528180000000-104.837572700000006636Roark, ChristinaAsst ProfessorKathrynHaskinsKathryn M Haskins39.74545800000000-104.83936910000000892Haskins, KathrynProfessorJohnKapplerJohn W Kappler39.73933130000000-104.862974600000006755Kappler, JohnDistinguished ProfessorRajWadwaRaj Paul Wadwa39.74404140000000-104.838394500000001956Wadwa, RajProfessorPeterGottliebPeter Ashley Gottlieb39.74404140000000-104.83839450000000252Gottlieb, PeterProfessorAuthorship 229838433095259Reed B, Crawford F, Hill RC, Jin N, White J, Krovi SH, Marrack P, Hansen K, Kappler JWThe Journal of experimental medicineReed B, Crawford F, Hill RC, Jin N, White J, Krovi SH, Marrack P, Hansen K, Kappler JW. Lysosomal cathepsin creates chimeric epitopes for diabetogenic CD4 T cells via transpeptidation. J Exp Med. 2021 02 01; 218(2).J Exp Med2021-02-01T00:00:002021Lysosomal cathepsin creates chimeric epitopes for diabetogenic CD4 T cells via transpeptidation.Authorship 247869734462258Alam M, Arunagiri A, Haataja L, Torres M, Larkin D, Kappler J, Jin N, Arvan PDiabetesAlam M, Arunagiri A, Haataja L, Torres M, Larkin D, Kappler J, Jin N, Arvan P. Predisposition to Proinsulin Misfolding as a Genetic Risk to Diet-Induced Diabetes. Diabetes. 2021 11; 70(11):2580-2594.Diabetes2021-08-30T00:00:002021Predisposition to Proinsulin Misfolding as a Genetic Risk to Diet-Induced Diabetes.Authorship 255190734994789Alam M, Arunagiri A, Haataja L, Torres M, Larkin D, Kappler J, Jin N, Arvan PDiabetesAlam M, Arunagiri A, Haataja L, Torres M, Larkin D, Kappler J, Jin N, Arvan P. Erratum. Predisposition to Proinsulin Misfolding as a Genetic Risk to Diet-Induced Diabetes. Diabetes 2021;70:2580-2594. Diabetes. 2022 Apr 01; 71(4):870.Diabetes2022-04-01T00:00:002022Erratum. Predisposition to Proinsulin Misfolding as a Genetic Risk to Diet-Induced Diabetes. Diabetes 2021;70:2580-2594.Authorship 275952436291615O'Brien RL, Matsuda J, Aydintug MK, Jin N, Phalke S, Born WKBiomoleculesO'Brien RL, Matsuda J, Aydintug MK, Jin N, Phalke S, Born WK. A Distinctive ?d T Cell Repertoire in NOD Mice Weakens Immune Regulation and Favors Diabetic Disease. Biomolecules. 2022 10 01; 12(10).Biomolecules2022-10-01T00:00:002022A Distinctive ?d T Cell Repertoire in NOD Mice Weakens Immune Regulation and Favors Diabetic Disease.true1Asst ProfessorAsst Professortrue1InstructorInstructortrue1Assoc Professor AdjointAssoc Professor Adjointtrue1ProfessorProfessortrue1ProfessorProfessortrue1InstructorInstructortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1Distinguished ProfessorDistinguished Professortrue1Research Senior InstructorResearch Senior Instructortrue1Associate ProfessorAssociate Professortrue1Distinguished ProfessorDistinguished Professortrue1ProfessorProfessor20101253Born WK, Huang Y, Jin N, Huang H, O'Brien RLImmunology and cell biologyBorn WK, Huang Y, Jin N, Huang H, O'Brien RL. Balanced approach of gammadelta T cells to type 2 immunity. Immunol Cell Biol. 2010 Mar-Apr; 88(3):269-74.Immunol Cell Biol2010-01-26T00:00:002010Balanced approach of gammadelta T cells to type 2 immunity.