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Benjamin Masao Akiyama

TitlePost-Doctoral Fellow
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-BioChem&Molecular Genetics

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    F32GM117730     (AKIYAMA, BENJAMIN)Aug 1, 2016 - Jul 31, 2018
    A pathogenic RNA that resists degradation: characterization of subgenomic flavivirus RNA
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Sparks H, Monogue B, Akiyama B, Kieft J, Beckham JD. Disruption of Zika Virus xrRNA1-Dependent sfRNA1 Production Results in Tissue-Specific Attenuated Viral Replication. Viruses. 2020 10 18; 12(10). PMID: 33080971.
      View in: PubMed
    2. Jones RA, Steckelberg AL, Vicens Q, Szucs MJ, Akiyama BM, Kieft JS. Different tertiary interactions create the same important 3D features in a distinct flavivirus xrRNA. RNA. 2021 Jan; 27(1):54-65. PMID: 33004436.
      View in: PubMed
    3. Steckelberg AL, Akiyama BM, Costantino DA, Sit TL, Nix JC, Kieft JS. A folded viral noncoding RNA blocks host cell exoribonucleases through a conformationally dynamic RNA structure. Proc Natl Acad Sci U S A. 2018 06 19; 115(25):6404-6409. PMID: 29866852.
      View in: PubMed
    4. Akiyama BM, Laurence HM, Massey AR, Costantino DA, Xie X, Yang Y, Shi PY, Nix JC, Beckham JD, Kieft JS. Zika virus produces noncoding RNAs using a multi-pseudoknot structure that confounds a cellular exonuclease. Science. 2016 12 02; 354(6316):1148-1152. PMID: 27934765.
      View in: PubMed
    5. Akiyama BM, Eiler D, Kieft JS. Structured RNAs that evade or confound exonucleases: function follows form. Curr Opin Struct Biol. 2016 Feb; 36:40-7. PMID: 26797676.
      View in: PubMed
    6. Jansson LI, Akiyama BM, Ooms A, Lu C, Rubin SM, Stone MD. Structural basis of template-boundary definition in Tetrahymena telomerase. Nat Struct Mol Biol. 2015 Nov; 22(11):883-8. PMID: 26436828.
      View in: PubMed
    7. Akiyama BM, Parks JW, Stone MD. The telomerase essential N-terminal domain promotes DNA synthesis by stabilizing short RNA-DNA hybrids. Nucleic Acids Res. 2015 Jun 23; 43(11):5537-49. PMID: 25940626.
      View in: PubMed
    8. Akiyama BM, Gomez A, Stone MD. A conserved motif in Tetrahymena thermophila telomerase reverse transcriptase is proximal to the RNA template and is essential for boundary definition. J Biol Chem. 2013 Jul 26; 288(30):22141-9. PMID: 23760279.
      View in: PubMed
    9. Akiyama BM, Stone MD. Structural biology: a solution to the telomerase puzzle. Nature. 2013 Apr 11; 496(7444):177-8. PMID: 23552897.
      View in: PubMed
    10. Akiyama BM, Loper J, Najarro K, Stone MD. The C-terminal domain of Tetrahymena thermophila telomerase holoenzyme protein p65 induces multiple structural changes in telomerase RNA. RNA. 2012 Apr; 18(4):653-60. PMID: 22315458.
      View in: PubMed
    11. Berman AJ, Akiyama BM, Stone MD, Cech TR. The RNA accordion model for template positioning by telomerase RNA during telomeric DNA synthesis. Nat Struct Mol Biol. 2011 Nov 20; 18(12):1371-5. PMID: 22101935.
      View in: PubMed
    12. Hengesbach M, Akiyama BM, Stone MD. Single-molecule analysis of telomerase structure and function. Curr Opin Chem Biol. 2011 Dec; 15(6):845-52. PMID: 22057212.
      View in: PubMed
    13. Akiyama BM, Stone MD. Assembly of complex RNAs by splinted ligation. Methods Enzymol. 2009; 469:27-46. PMID: 20946783.
      View in: PubMed
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