Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Last Name

Contact Us
If you have any questions or feedback please contact us.

Benjamin Masao Akiyama

TitlePost-Doctoral Fellow
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-BioChem&Molecular Genetics

    Collapse Research 
    Collapse research activities and funding
    F32GM117730     (AKIYAMA, BENJAMIN)Aug 1, 2016 - Jul 31, 2018
    A pathogenic RNA that resists degradation: characterization of subgenomic flavivirus RNA
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Steckelberg AL, Akiyama BM, Costantino DA, Sit TL, Nix JC, Kieft JS. A folded viral noncoding RNA blocks host cell exoribonucleases through a conformationally dynamic RNA structure. Proc Natl Acad Sci U S A. 2018 06 19; 115(25):6404-6409. PMID: 29866852.
      View in: PubMed
    2. Akiyama BM, Laurence HM, Massey AR, Costantino DA, Xie X, Yang Y, Shi PY, Nix JC, Beckham JD, Kieft JS. Zika virus produces noncoding RNAs using a multi-pseudoknot structure that confounds a cellular exonuclease. Science. 2016 12 02; 354(6316):1148-1152. PMID: 27934765.
      View in: PubMed
    3. Akiyama BM, Eiler D, Kieft JS. Structured RNAs that evade or confound exonucleases: function follows form. Curr Opin Struct Biol. 2016 Feb; 36:40-7. PMID: 26797676.
      View in: PubMed
    4. Jansson LI, Akiyama BM, Ooms A, Lu C, Rubin SM, Stone MD. Structural basis of template-boundary definition in Tetrahymena telomerase. Nat Struct Mol Biol. 2015 Nov; 22(11):883-8. PMID: 26436828; PMCID: PMC4654688.
    5. Akiyama BM, Parks JW, Stone MD. The telomerase essential N-terminal domain promotes DNA synthesis by stabilizing short RNA-DNA hybrids. Nucleic Acids Res. 2015 Jun 23; 43(11):5537-49. PMID: 25940626; PMCID: PMC4477650.
    6. Akiyama BM, Gomez A, Stone MD. A conserved motif in Tetrahymena thermophila telomerase reverse transcriptase is proximal to the RNA template and is essential for boundary definition. J Biol Chem. 2013 Jul 26; 288(30):22141-9. PMID: 23760279; PMCID: PMC3724666.
    7. Akiyama BM, Stone MD. Structural biology: a solution to the telomerase puzzle. Nature. 2013 Apr 11; 496(7444):177-8. PMID: 23552897.
      View in: PubMed
    8. Akiyama BM, Loper J, Najarro K, Stone MD. The C-terminal domain of Tetrahymena thermophila telomerase holoenzyme protein p65 induces multiple structural changes in telomerase RNA. RNA. 2012 Apr; 18(4):653-60. PMID: 22315458; PMCID: PMC3312553.
    9. Berman AJ, Akiyama BM, Stone MD, Cech TR. The RNA accordion model for template positioning by telomerase RNA during telomeric DNA synthesis. Nat Struct Mol Biol. 2011 Nov 20; 18(12):1371-5. PMID: 22101935; PMCID: PMC3230705.
    10. Hengesbach M, Akiyama BM, Stone MD. Single-molecule analysis of telomerase structure and function. Curr Opin Chem Biol. 2011 Dec; 15(6):845-52. PMID: 22057212; PMCID: PMC4972019.
    11. Akiyama BM, Stone MD. Assembly of complex RNAs by splinted ligation. Methods Enzymol. 2009; 469:27-46. PMID: 20946783.
      View in: PubMed
    Akiyama's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    Co-Authors Expand Description
    Similar People Expand Description
    Same Department Expand Description
    Physical Neighbors Expand Description

    Copyright © 2017 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.10.0)