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Scott Ian Vrieze

TitleAsst Professor
InstitutionUniversity of Colorado Boulder
DepartmentInstitute for Behav Genetics
Phone303/492-1743
    Other Positions
    TitleAsst Professor
    InstitutionUniversity of Colorado Boulder
    DepartmentPsych-Psychology

    TitleAsst Professor
    InstitutionUniversity of Colorado Boulder
    DepartmentInstitute for Behav Genetics


    Collapse Research 
    Collapse research activities and funding
    R01AA023974     (VRIEZE, SCOTT IAN)Sep 25, 2014 - Aug 30, 2017
    NIH/NIAAA
    Social Media, Online Measures, and Substance Use Development in Adolescent Twins
    Role: Principal Investigator

    R01DA037904     (VRIEZE, SCOTT IAN)May 1, 2015 - Apr 30, 2020
    NIH/NIDA
    Genetic Association Meta-Analyses of Smoking and Drinking for the Sequencing Age
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Clark SL, McClay JL, Adkins DE, Kumar G, Aberg KA, Nerella S, Xie L, Collins AL, Crowley JJ, Quackenbush CR, Hilliard CE, Shabalin AA, Vrieze SI, Peterson RE, Copeland WE, Silberg JL, McGue M, Maes H, Iacono WG, Sullivan PF, Costello EJ, van den Oord EJ. Deep Sequencing of 71 Candidate Genes to Characterize Variation Associated with Alcohol Dependence. Alcohol Clin Exp Res. 2017 Apr; 41(4):711-718. PMID: 28196272.
      View in: PubMed
    2. Liu M, Malone SM, Vaidyanathan U, Keller MC, Abecasis G, McGue M, Iacono WG, Vrieze SI. Psychophysiological endophenotypes to characterize mechanisms of known schizophrenia genetic loci. Psychol Med. 2017 Apr; 47(6):1116-1125. PMID: 27995817.
      View in: PubMed
    3. Das S, Forer L, Schönherr S, Sidore C, Locke AE, Kwong A, Vrieze SI, Chew EY, Levy S, McGue M, Schlessinger D, Stambolian D, Loh PR, Iacono WG, Swaroop A, Scott LJ, Cucca F, Kronenberg F, Boehnke M, Abecasis GR, Fuchsberger C. Next-generation genotype imputation service and methods. Nat Genet. 2016 Oct; 48(10):1284-7. PMID: 27571263.
      View in: PubMed
    4. McCarthy S, Das S, Kretzschmar W, Delaneau O, Wood AR, Teumer A, Kang HM, Fuchsberger C, Danecek P, Sharp K, Luo Y, Sidore C, Kwong A, Timpson N, Koskinen S, Vrieze S, Scott LJ, Zhang H, Mahajan A, Veldink J, Peters U, Pato C, van Duijn CM, Gillies CE, Gandin I, Mezzavilla M, Gilly A, Cocca M, Traglia M, Angius A, Barrett JC, Boomsma D, Branham K, Breen G, Brummett CM, Busonero F, Campbell H, Chan A, Chen S, Chew E, Collins FS, Corbin LJ, Smith GD, Dedoussis G, Dorr M, Farmaki AE, Ferrucci L, Forer L, Fraser RM, Gabriel S, Levy S, Groop L, Harrison T, Hattersley A, Holmen OL, Hveem K, Kretzler M, Lee JC, McGue M, Meitinger T, Melzer D, Min JL, Mohlke KL, Vincent JB, Nauck M, Nickerson D, Palotie A, Pato M, Pirastu N, McInnis M, Richards JB, Sala C, Salomaa V, Schlessinger D, Schoenherr S, Slagboom PE, Small K, Spector T, Stambolian D, Tuke M, Tuomilehto J, Van den Berg LH, Van Rheenen W, Volker U, Wijmenga C, Toniolo D, Zeggini E, Gasparini P, Sampson MG, Wilson JF, Frayling T, de Bakker PI, Swertz MA, McCarroll S, Kooperberg C, Dekker A, Altshuler D, Willer C, Iacono W, Ripatti S, Soranzo N, Walter K, Swaroop A, Cucca F, Anderson CA, Myers RM, Boehnke M, McCarthy MI, Durbin R. A reference panel of 64,976 haplotypes for genotype imputation. Nat Genet. 2016 Oct; 48(10):1279-83. PMID: 27548312.
      View in: PubMed
    5. Iacono WG, Malone SM, Vrieze SI. Endophenotype best practices. Int J Psychophysiol. 2017 Jan; 111:115-144. PMID: 27473600.
      View in: PubMed
    6. Chang LC, Li B, Fang Z, Vrieze S, McGue M, Iacono WG, Tseng GC, Chen W. A computational method for genotype calling in family-based sequencing data. BMC Bioinformatics. 2016 Jan 16; 17:37. PMID: 26772743; PMCID: PMC4715317.
    7. Vaidyanathan U, Vrieze SI, Iacono WG. The Power of Theory, Research Design, and Transdisciplinary Integration in Moving Psychopathology Forward. Psychol Inq. 2015; 26(3):209-230. PMID: 27030789.
      View in: PubMed
    8. Vaidyanathan U, Vrieze SI, Iacono WG. THE ART OF SMART SCIENCE: WEAVING THEORY AND RISKY STUDY DESIGN INTO PSYCHOPATHOLOGY RESEARCH AND RDOC. Psychol Inq. 2015; 26(3):286-292. PMID: 27019570.
      View in: PubMed
    9. Iacono WG, Malone SM, Vaidyanathan U, Vrieze SI. Genome-wide scans of genetic variants for psychophysiological endophenotypes: a methodological overview. Psychophysiology. 2014 Dec; 51(12):1207-24. PMID: 25387703; PMCID: PMC4231489.
    10. Vrieze SI, Malone SM, Vaidyanathan U, Kwong A, Kang HM, Zhan X, Flickinger M, Irons D, Jun G, Locke AE, Pistis G, Porcu E, Levy S, Myers RM, Oetting W, McGue M, Abecasis G, Iacono WG. In search of rare variants: preliminary results from whole genome sequencing of 1,325 individuals with psychophysiological endophenotypes. Psychophysiology. 2014 Dec; 51(12):1309-20. PMID: 25387710; PMCID: PMC4231480.
    11. Vrieze SI, Malone SM, Pankratz N, Vaidyanathan U, Miller MB, Kang HM, McGue M, Abecasis G, Iacono WG. Genetic associations of nonsynonymous exonic variants with psychophysiological endophenotypes. Psychophysiology. 2014 Dec; 51(12):1300-8. PMID: 25387709; PMCID: PMC4231532.
    12. Iacono WG, Vaidyanathan U, Vrieze SI, Malone SM. Knowns and unknowns for psychophysiological endophenotypes: integration and response to commentaries. Psychophysiology. 2014 Dec; 51(12):1339-47. PMID: 25387720; PMCID: PMC4231488.
    13. Pistis G, Porcu E, Vrieze SI, Sidore C, Steri M, Danjou F, Busonero F, Mulas A, Zoledziewska M, Maschio A, Brennan C, Lai S, Miller MB, Marcelli M, Urru MF, Pitzalis M, Lyons RH, Kang HM, Jones CM, Angius A, Iacono WG, Schlessinger D, McGue M, Cucca F, Abecasis GR, Sanna S. Rare variant genotype imputation with thousands of study-specific whole-genome sequences: implications for cost-effective study designs. Eur J Hum Genet. 2015 Jul; 23(7):975-83. PMID: 25293720; PMCID: PMC4463504.
    14. Irons DE, Iacono WG, Oetting WS, Kirkpatrick RM, Vrieze SI, Miller MB, McGue M. Gamma-aminobutyric acid system genes--no evidence for a role in alcohol use and abuse in a community-based sample. Alcohol Clin Exp Res. 2014 Apr; 38(4):938-47. PMID: 24460875; PMCID: PMC3984361.
    15. Vrieze SI, Vaidyanathan U, Hicks BM, Iacono WG, McGue M. The role of constraint in the development of nicotine, marijuana, and alcohol dependence in young adulthood. Behav Genet. 2014 Jan; 44(1):14-24. PMID: 24343204; PMCID: PMC3951055.
    16. Vrieze SI, Feng S, Miller MB, Hicks BM, Pankratz N, Abecasis GR, Iacono WG, McGue M. Rare nonsynonymous exonic variants in addiction and behavioral disinhibition. Biol Psychiatry. 2014 May 15; 75(10):783-9. PMID: 24094508; PMCID: PMC3975816.
    17. Vrieze SI, Docherty A, Thuras P, Arbisi P, Iacono WG, Sponheim S, Erbes CR, Siegel W, Leskela J. Best practices: The electronic medical record is an invaluable clinical tool: let's start using it. Psychiatr Serv. 2013 Oct; 64(10):946-9. PMID: 23946012.
      View in: PubMed
    18. McGue M, Zhang Y, Miller MB, Basu S, Vrieze S, Hicks B, Malone S, Oetting WS, Iacono WG. A genome-wide association study of behavioral disinhibition. Behav Genet. 2013 Sep; 43(5):363-73. PMID: 23942779; PMCID: PMC3886341.
    19. Vrieze SI, McGue M, Miller MB, Hicks BM, Iacono WG. Three mutually informative ways to understand the genetic relationships among behavioral disinhibition, alcohol use, drug use, nicotine use/dependence, and their co-occurrence: twin biometry, GCTA, and genome-wide scoring. Behav Genet. 2013 Mar; 43(2):97-107. PMID: 23362009; PMCID: PMC3579160.
    20. Vrieze SI, Iacono WG, McGue M. Confluence of genes, environment, development, and behavior in a post Genome-Wide Association Study world. Dev Psychopathol. 2012 Nov; 24(4):1195-214. PMID: 23062291; PMCID: PMC3476066.
    21. Vrieze SI, Hicks BM, Iacono WG, McGue M. Decline in genetic influence on the co-occurrence of alcohol, marijuana, and nicotine dependence symptoms from age 14 to 29. Am J Psychiatry. 2012 Oct; 169(10):1073-81. PMID: 22983309; PMCID: PMC3513559.
    22. Vrieze SI, McGue M, Iacono WG. The interplay of genes and adolescent development in substance use disorders: leveraging findings from GWAS meta-analyses to test developmental hypotheses about nicotine consumption. Hum Genet. 2012 Jun; 131(6):791-801. PMID: 22492059; PMCID: PMC3407593.
    23. Vrieze SI, Perlman G, Krueger RF, Iacono WG. Is the continuity of externalizing psychopathology the same in adolescents and middle-aged adults? A test of the externalizing spectrum's developmental coherence. J Abnorm Child Psychol. 2012 Apr; 40(3):459-70. PMID: 21932056; PMCID: PMC3292691.
    24. Vrieze SI. Model selection and psychological theory: a discussion of the differences between the Akaike information criterion (AIC) and the Bayesian information criterion (BIC). Psychol Methods. 2012 Jun; 17(2):228-43. PMID: 22309957; PMCID: PMC3366160.
    25. Vrieze SI, McGue M, Miller MB, Legrand LN, Schork NJ, Iacono WG. An assessment of the individual and collective effects of variants on height using twins and a developmentally informative study design. PLoS Genet. 2011 Dec; 7(12):e1002413. PMID: 22174699; PMCID: PMC3234218.
    26. Vrieze SI, Grove WM. Multidimensional assessment of criminal recidivism: problems, pitfalls, and proposed solutions. Psychol Assess. 2010 Jun; 22(2):382-95. PMID: 20528065; PMCID: PMC2922019.
    27. Grove WM, Vrieze SI. An exploration of the base rate scores of the Millon Clinical Multiaxial Inventory-III. Psychol Assess. 2009 Mar; 21(1):57-67. PMID: 19290766.
      View in: PubMed
    28. Vrieze SI, Grove WM. Predicting sex offender recidivism. I. Correcting for item overselection and accuracy overestimation in scale development. II. Sampling error-induced attenuation of predictive validity over base rate information. Law Hum Behav. 2008 Jun; 32(3):266-78. PMID: 17610052.
      View in: PubMed
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