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Mita Das

InstitutionUniversity of Colorado Denver - Anschutz Medical Campus

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    R01HL064917     (DAS, MITA)Apr 1, 2000 - Dec 31, 2012
    PKC Isozymes in Hypoxia-Induced Fibroblast Proliferation
    Role: Principal Investigator

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Zhang H, Okamoto M, Panzhinskiy E, Zawada WM, Das M. PKCd/midkine pathway drives hypoxia-induced proliferation and differentiation of human lung epithelial cells. Am J Physiol Cell Physiol. 2014 Apr 01; 306(7):C648-58. PMID: 24500281; PMCID: PMC3962599.
    2. Topchiy E, Panzhinskiy E, Griffin WS, Barger SW, Das M, Zawada WM. Nox4-generated superoxide drives angiotensin II-induced neural stem cell proliferation. Dev Neurosci. 2013; 35(4):293-305. PMID: 23751520; PMCID: PMC3889712.
    3. Panzhinskiy E, Zawada WM, Stenmark KR, Das M. Hypoxia induces unique proliferative response in adventitial fibroblasts by activating PDGFß receptor-JNK1 signalling. Cardiovasc Res. 2012 Aug 01; 95(3):356-65. PMID: 22735370; PMCID: PMC3400360.
    4. Zawada WM, Banninger GP, Thornton J, Marriott B, Cantu D, Rachubinski AL, Das M, Griffin WS, Jones SM. Generation of reactive oxygen species in 1-methyl-4-phenylpyridinium (MPP+) treated dopaminergic neurons occurs as an NADPH oxidase-dependent two-wave cascade. J Neuroinflammation. 2011 Oct 05; 8:129. PMID: 21975039; PMCID: PMC3198931.
    5. Augoff K, Das M, Bialkowska K, McCue B, Plow EF, Sossey-Alaoui K. miR-31 is a broad regulator of ß1-integrin expression and function in cancer cells. Mol Cancer Res. 2011 Nov; 9(11):1500-8. PMID: 21875932; PMCID: PMC3219821.
    6. Shields KM, Panzhinskiy E, Burns N, Zawada WM, Das M. Mitogen-activated protein kinase phosphatase-1 is a key regulator of hypoxia-induced vascular endothelial growth factor expression and vessel density in lung. Am J Pathol. 2011 Jan; 178(1):98-109. PMID: 21224048; PMCID: PMC3069890.
    7. Grammatopoulos TN, Jones SM, Yoshimura M, Hoover BR, Das M, Snyder EY, Larson GA, Zahniser NR, Tabakoff B, Zawada WM. Neurotransplantation of stem cells genetically modified to express human dopamine transporter reduces alcohol consumption. Stem Cell Res Ther. 2010 Dec 01; 1(5):36. PMID: 21122109; PMCID: PMC3025438.
    8. Das M, Burns N, Wilson SJ, Zawada WM, Stenmark KR. Hypoxia exposure induces the emergence of fibroblasts lacking replication repressor signals of PKCzeta in the pulmonary artery adventitia. Cardiovasc Res. 2008 Jun 01; 78(3):440-8. PMID: 18218684.
      View in: PubMed
    9. Ahmadi FA, Grammatopoulos TN, Poczobutt AM, Jones SM, Snell LD, Das M, Zawada WM. Dopamine selectively sensitizes dopaminergic neurons to rotenone-induced apoptosis. Neurochem Res. 2008 May; 33(5):886-901. PMID: 17992568.
      View in: PubMed
    10. Stenmark KR, Davie N, Frid M, Gerasimovskaya E, Das M. Role of the adventitia in pulmonary vascular remodeling. Physiology (Bethesda). 2006 Apr; 21:134-45. PMID: 16565479.
      View in: PubMed
    11. Short MD, Fox SM, Lam CF, Stenmark KR, Das M. Protein kinase Czeta attenuates hypoxia-induced proliferation of fibroblasts by regulating MAP kinase phosphatase-1 expression. Mol Biol Cell. 2006 Apr; 17(4):1995-2008. PMID: 16467381; PMCID: PMC1415328.
    12. Short M, Fox S, Stenmark KR, Das M. Hypoxia-induced alterations in protein kinase C zeta signaling result in augmented fibroblast proliferation. Chest. 2005 Dec; 128(6 Suppl):582S. PMID: 16373847.
      View in: PubMed
    13. Short M, Nemenoff RA, Zawada WM, Stenmark KR, Das M. Hypoxia induces differentiation of pulmonary artery adventitial fibroblasts into myofibroblasts. Am J Physiol Cell Physiol. 2004 Feb; 286(2):C416-25. PMID: 14561589.
      View in: PubMed
    14. Stenmark KR, Gerasimovskaya E, Nemenoff RA, Das M. Hypoxic activation of adventitial fibroblasts: role in vascular remodeling. Chest. 2002 Dec; 122(6 Suppl):326S-334S. PMID: 12475810.
      View in: PubMed
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