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Ken Liechty

TitleProfessor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-SRG

    Collapse Overview 
    Collapse overview
    Dr. Kenneth Liechty is a Pediatric and Fetal Surgeon. His research has been focused primarily in the field of wound healing and regenerative medicine, with an emphasis on elucidating the mechanisms involved in the regenerative response to injury in the fetus, the role of stem cells in tissue repair, and the correction of abnormal healing in the adult. His team has contributed significantly to the understanding of regenerative healing in the skin and tendon, as well as the correction of impaired healing in diabetics. Dr. Liechty’s research team has pioneered the role of dysregulation of microRNAs in the diabetic wound healing impairment and the mechanisms of stem cell and gene therapy in the correction of this impairment. He and his team are developing novel treatment paradigms using stem cells and gene therapy strategies to promote healing and tissue regeneration in multiple tissues by modulating the inflammatory response, angiogenesis, the composition of the extracellular matrix, and the progenitor cell content. The goal of this regenerative medicine approach is to restore normal tissue architecture and function and to prevent the complications of impaired healing or scar formation following injury.

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Louiselle AE, Niemiec SM, Zgheib C, Liechty KW. Macrophage polarization and diabetic wound healing. Transl Res. 2021 10; 236:109-116. PMID: 34089902.
      View in: PubMed
    2. Louiselle AE, Niemiec S, Azeltine M, Mundra L, French B, Zgheib C, Liechty KW. Evaluation of skin care concerns and patient's perception of the effect of NanoSilk Cream on facial skin. J Cosmet Dermatol. 2021 May 02. PMID: 33934488.
      View in: PubMed
    3. Niemiec SM, Hilton SA, Wallbank A, Azeltine M, Louiselle AE, Elajaili H, Allawzi A, Xu J, Mattson C, Dewberry LC, Hu J, Singh S, Sakthivel TS, Sea S, Nozik-Grayck E, Smith B, Zgheib C, Liechty KW. Cerium oxide nanoparticle delivery of microRNA-146a for local treatment of acute lung injury. Nanomedicine. 2021 06; 34:102388. PMID: 33753282.
      View in: PubMed
    4. Niemiec SM, Louiselle AE, Liechty KW, Zgheib C. Role of microRNAs in Pressure Ulcer Immune Response, Pathogenesis, and Treatment. Int J Mol Sci. 2020 Dec 23; 22(1). PMID: 33374656.
      View in: PubMed
    5. Porter AC, Behrendt NJ, Zaretsky MV, Liechty KW, Wood C, Chow F, Galan HL. Continuous local bupivacaine wound infusion reduces oral opioid use for acute postoperative pain control following myelomeningocele repair. Am J Obstet Gynecol MFM. 2021 03; 3(2):100296. PMID: 33485023.
      View in: PubMed
    6. Guglielmetti LC, Estrada AE, Phillips R, Staerkle RF, Gien J, Kinsella JP, Liechty KW, Marwan AI, Vuille-Dit-Bille RN. Congenital diaphragmatic hernias: Severe defect grade predicts the need for fundoplication. Medicine (Baltimore). 2020 Dec 04; 99(49):e23383. PMID: 33285723.
      View in: PubMed
    7. Niemiec SM, Louiselle AE, Hilton SA, Dewberry LC, Zhang L, Azeltine M, Xu J, Singh S, Sakthivel TS, Seal S, Liechty KW, Zgheib C. Nanosilk Increases the Strength of Diabetic Skin and Delivers CNP-miR146a to Improve Wound Healing. Front Immunol. 2020; 11:590285. PMID: 33193424.
      View in: PubMed
    8. Singh S, Cortes G, Kumar U, Sakthivel TS, Niemiec SM, Louiselle AE, Azeltine-Bannerman M, Zgheib C, Liechty KW, Seal S. Silk fibroin nanofibrous mats for visible sensing of oxidative stress in cutaneous wounds. Biomater Sci. 2020 Nov 07; 8(21):5900-5910. PMID: 32975269.
      View in: PubMed
    9. Hodges MM, Zgheib C, Liechty KW. A Large Mammalian Model of Myocardial Regeneration After Myocardial Infarction in Fetal Sheep. Adv Wound Care (New Rochelle). 2021 04; 10(4):174-190. PMID: 32496979.
      View in: PubMed
    10. Vuille-Dit-Bille RN, Liechty KW, Verrey F, Guglielmetti LC. SARS-CoV-2 receptor ACE2 gene expression in small intestine correlates with age. Amino Acids. 2020 Jul; 52(6-7):1063-1065. PMID: 32627059.
      View in: PubMed
    11. Phillips RC, Shahi N, Leopold D, Levek C, Shirek G, Hilton S, Hyslop R, Gien J, Kinsella JP, Buckvold S, Liechty KW, Kim JS, Marwan AI. Thromboelastography-guided management of coagulopathy in neonates with congenital diaphragmatic hernia supported by extracorporeal membrane oxygenation. Pediatr Surg Int. 2020 Sep; 36(9):1027-1033. PMID: 32607833.
      View in: PubMed
    12. Liechty C, Hu J, Zhang L, Liechty KW, Xu J. Role of microRNA-21 and Its Underlying Mechanisms in Inflammatory Responses in Diabetic Wounds. Int J Mol Sci. 2020 May 08; 21(9). PMID: 32397166.
      View in: PubMed
    13. Dewberry LC, Kalia N, Vazquez J, Hilton SA, Zaretsky MV, Behrendt N, Galan HL, Marwan AI, Liechty KW. Determining maternal risk factors for gastroschisis using colorado's birth registry database. J Pediatr Surg. 2020 Jun; 55(6):1002-1005. PMID: 32173119.
      View in: PubMed
    14. Hu J, Zhang L, Liechty C, Zgheib C, Hodges MM, Liechty KW, Xu J. Long Noncoding RNA GAS5 Regulates Macrophage Polarization and Diabetic Wound Healing. J Invest Dermatol. 2020 08; 140(8):1629-1638. PMID: 32004569.
      View in: PubMed
    15. Sener G, Hilton SA, Osmond MJ, Zgheib C, Newsom JP, Dewberry L, Singh S, Sakthivel TS, Seal S, Liechty KW, Krebs MD. Injectable, self-healable zwitterionic cryogels with sustained microRNA - cerium oxide nanoparticle release promote accelerated wound healing. Acta Biomater. 2020 01 01; 101:262-272. PMID: 31726250.
      View in: PubMed
    16. Leopold DK, Phillips RC, Shahi N, Gien J, Marwan AI, Kinsella JP, Mulligan J, Liechty KW, Moulton SL. Low postnatal CRI values are associated with the need for ECMO in newborns with CDH. J Pediatr Surg. 2020 Jan; 55(1):39-44. PMID: 31679772.
      View in: PubMed
    17. Dewberry LC, Trecartin A, Galambos C, Hilton SA, Dannull K, Zaretsky MV, Behrendt N, Galan HL, Marwan AI, Liechty KW. A congenital cystic pulmonary airway malformation occurring together with both an extralobar pulmonary sequestration and an esophageal duplication cyst. Clin Case Rep. 2020 Jan; 8(1):18-23. PMID: 31998479.
      View in: PubMed
    18. Dewberry LC, Hilton SA, Vuille-Dit-Bille RN, Liechty KW. Is Tapering Enteroplasty an Alternative to Resection of Dilated Bowel in Small Intestinal Atresia? J Surg Res. 2020 02; 246:1-5. PMID: 31541708.
      View in: PubMed
    19. Dewberry L, Hilton S, Gien J, Liechty KW, Marwan AI. Flap repair in congenital diaphragmatic hernia leads to lower rates of recurrence. J Pediatr Surg. 2019 Dec; 54(12):2487-2491. PMID: 31515112.
      View in: PubMed
    20. Dewberry LC, Hilton SA, Zaretsky MV, Behrendt N, Galan HL, Marwan AI, Liechty KW. Examination of Prenatal Sonographic Findings: Intra-Abdominal Bowel Dilation Predicts Poor Gastroschisis Outcomes. Fetal Diagn Ther. 2020; 47(3):245-250. PMID: 31454815.
      View in: PubMed
    21. Dewberry LC, Hilton SA, Vuille-Dit-Bille RN, Liechty KW. Tapering duodenoplasty: a beneficial adjunct in the treatment of congenital duodenal obstruction. J Int Med Res. 2020 Jan; 48(1):300060519862109. PMID: 31353994.
      View in: PubMed
    22. Hilton SA, Dewberry LC, Hodges MM, Hu J, Xu J, Liechty KW, Zgheib C. Mesenchymal stromal cells contract collagen more efficiently than dermal fibroblasts: Implications for cytotherapy. PLoS One. 2019; 14(7):e0218536. PMID: 31306414.
      View in: PubMed
    23. Leu S, Staerkle RF, Gaukel S, Fink L, Soll C, Aasen DM, Liechty K, Vitz M, Ramseier LE, Vuille-Dit-Bille RN. Impact of Sleep Deprivation on Surgical Laparoscopic Performance in Novices: A Computer-based Crossover Study. Surg Laparosc Endosc Percutan Tech. 2019 Jun; 29(3):162-168. PMID: 30817696.
      View in: PubMed
    24. Hilton SA, Hodges MM, Dewberry LC, Handler M, Galan HL, Zaretsky MV, Behrendt N, Marwan AI, Liechty KW. MOMS Plus: Single-Institution Review of Outcomes for Extended BMI Criteria for Open Fetal Repair of Myelomeningocele. Fetal Diagn Ther. 2019; 46(6):411-414. PMID: 31048584.
      View in: PubMed
    25. Hodges MM, Zgheib C, Xu J, Hu J, Dewberry LC, Hilton SA, Allukian MW, Gorman JH, Gorman RC, Liechty KW. Differential Expression of Transforming Growth Factor-ß1 Is Associated With Fetal Regeneration After Myocardial Infarction. Ann Thorac Surg. 2019 07; 108(1):59-66. PMID: 30690019.
      View in: PubMed
    26. Zgheib C, Hilton SA, Dewberry LC, Hodges MM, Ghatak S, Xu J, Singh S, Roy S, Sen CK, Seal S, Liechty KW. Use of Cerium Oxide Nanoparticles Conjugated with MicroRNA-146a to Correct the Diabetic Wound Healing Impairment. J Am Coll Surg. 2019 01; 228(1):107-115. PMID: 30359833.
      View in: PubMed
    27. Deeney S, Howley LW, Hodges M, Liechty KW, Marwan AI, Gien J, Kinsella JP, Crombleholme TM. Impact of Objective Echocardiographic Criteria for Timing of Congenital Diaphragmatic Hernia Repair. J Pediatr. 2018 01; 192:99-104.e4. PMID: 29106923.
      View in: PubMed
    28. Zaretsky MV, Liechty KW, Galan HL, Behrendt NJ, Reeves S, Marwan AI, Wilkinson C, Handler M, Lagueux M, Crombleholme TM. Modified Hysterotomy Closure Technique for Open Fetal Surgery. Fetal Diagn Ther. 2018; 44(2):105-111. PMID: 28873371.
      View in: PubMed
    29. Xu J, Zgheib C, Hodges MM, Caskey RC, Hu J, Liechty KW. Mesenchymal stem cells correct impaired diabetic wound healing by decreasing ECM proteolysis. Physiol Genomics. 2017 Oct 01; 49(10):541-548. PMID: 28842435.
      View in: PubMed
    30. Zgheib C, Hodges MM, Allukian MW, Xu J, Spiller KL, Gorman JH, Gorman RC, Liechty KW. Cardiac Progenitor Cell Recruitment Drives Fetal Cardiac Regeneration by Enhanced Angiogenesis. Ann Thorac Surg. 2017 Dec; 104(6):1968-1975. PMID: 28821329.
      View in: PubMed
    31. Zgheib C, Hodges MM, Hu J, Liechty KW, Xu J. Long non-coding RNA Lethe regulates hyperglycemia-induced reactive oxygen species production in macrophages. PLoS One. 2017; 12(5):e0177453. PMID: 28494015.
      View in: PubMed
    32. Zaretsky MV, Manchester DK, Galan HL, Behrendt NJ, Marwan AI, Liechty KW, Crombleholme TM. Case report of myometrial window following fetoscopic treatment of twin-twin transfusion syndrome: indications of underlying collagen vascular disease? Clin Case Rep. 2017 06; 5(6):975-979. PMID: 28588850.
      View in: PubMed
    33. Abou Chaar MK, Meyers ML, Tucker BD, Galan HL, Liechty KW, Crombleholme TM, Marwan AI. Twin pregnancy complicated by esophageal atresia, duodenal atresia, gastric perforation, and hypoplastic left heart structures in one twin: a case report and review of the literature. J Med Case Rep. 2017 Mar 18; 11(1):64. PMID: 28314387.
      View in: PubMed
    34. Balaji S, Wang X, King A, Le LD, Bhattacharya SS, Moles CM, Butte MJ, de Jesus Perez VA, Liechty KW, Wight TN, Crombleholme TM, Bollyky PL, Keswani SG. Interleukin-10-mediated regenerative postnatal tissue repair is dependent on regulation of hyaluronan metabolism via fibroblast-specific STAT3 signaling. FASEB J. 2017 03; 31(3):868-881. PMID: 27903619.
      View in: PubMed
    35. Zgheib C, Hodges M, Hu J, Beason DP, Soslowsky LJ, Liechty KW, Xu J. Mechanisms of mesenchymal stem cell correction of the impaired biomechanical properties of diabetic skin: The role of miR-29a. Wound Repair Regen. 2016 03; 24(2):237-46. PMID: 26808714.
      View in: PubMed
    36. Zgheib C, Liechty KW. Shedding light on miR-26a: Another key regulator of angiogenesis in diabetic wound healing. J Mol Cell Cardiol. 2016 Mar; 92:203-5. PMID: 26906635.
      View in: PubMed
    37. Zgheib C, Xu J, Mallette AC, Caskey RC, Zhang L, Hu J, Liechty KW. SCF increases in utero-labeled stem cells migration and improves wound healing. Wound Repair Regen. 2015 Jul-Aug; 23(4):583-90. PMID: 26032674.
      View in: PubMed
    38. Xu J, Zgheib C, Hu J, Wu W, Zhang L, Liechty KW. The role of microRNA-15b in the impaired angiogenesis in diabetic wounds. Wound Repair Regen. 2014 Sep-Oct; 22(5):671-7. PMID: 25059098.
      View in: PubMed
    39. Caskey RC, Zgheib C, Morris M, Allukian M, Dorsett-Martin W, Xu J, Wu W, Liechty KW. Dysregulation of collagen production in diabetes following recurrent skin injury: contribution to the development of a chronic wound. Wound Repair Regen. 2014 Jul-Aug; 22(4):515-20. PMID: 24898050.
      View in: PubMed
    40. Connizzo BK, Bhatt PR, Liechty KW, Soslowsky LJ. Diabetes alters mechanical properties and collagen fiber re-alignment in multiple mouse tendons. Ann Biomed Eng. 2014 Sep; 42(9):1880-8. PMID: 24833253.
      View in: PubMed
    41. Zgheib C, Allukian MW, Xu J, Morris MW, Caskey RC, Herdrich BJ, Hu J, Gorman JH, Gorman RC, Liechty KW. Mammalian fetal cardiac regeneration after myocardial infarction is associated with differential gene expression compared with the adult. Ann Thorac Surg. 2014 May; 97(5):1643-50. PMID: 24792251.
      View in: PubMed
    42. Morris MW, Allukian M, Herdrich BJ, Caskey RC, Zgheib C, Xu J, Dorsett-Martin W, Mitchell ME, Liechty KW. Modulation of the inflammatory response by increasing fetal wound size or interleukin-10 overexpression determines wound phenotype and scar formation. Wound Repair Regen. 2014 May-Jun; 22(3):406-14. PMID: 24844340.
      View in: PubMed
    43. Zgheib C, Xu J, Liechty KW. Targeting Inflammatory Cytokines and Extracellular Matrix Composition to Promote Wound Regeneration. Adv Wound Care (New Rochelle). 2014 Apr 01; 3(4):344-355. PMID: 24757589.
      View in: PubMed
    44. Morris MW, Liechty KW. Cardiac Progenitor Cells in Myocardial Infarction Wound Healing: A Critical Review. Adv Wound Care (New Rochelle). 2013 Jul; 2(6):317-326. PMID: 24527353.
      View in: PubMed
    45. Allukian M, Xu J, Morris M, Caskey R, Dorsett-Martin W, Plappert T, Griswold M, Gorman JH, Gorman RC, Liechty KW. Mammalian cardiac regeneration after fetal myocardial infarction requires cardiac progenitor cell recruitment. Ann Thorac Surg. 2013 Jul; 96(1):163-70. PMID: 23816072.
      View in: PubMed
    46. Morris MW, Cauthen W, Bofill JA, Blewett CJ, Liechty KW. Retroperitoneal lymphatic malformation and transverse testicular ectopia: a unique clinical presentation. J Pediatr Surg. 2013 Apr; 48(4):e17-20. PMID: 23583159.
      View in: PubMed
    47. Caskey RC, Liechty KW. Novel animal models for tracking the fate and contributions of bone marrow derived cells in diabetic healing. Methods Mol Biol. 2013; 1037:99-115. PMID: 24029932.
      View in: PubMed
    48. DiBardino DJ, Shores JC, Sheth M, Taylor M, Liechty K, Salazar JD. Coordinated cardiac delivery: reducing mortality in high risk fetal cardiac lesions at the University of Mississippi Medical Center. J Miss State Med Assoc. 2012 Dec; 53(12):400, 403-4. PMID: 23461044.
      View in: PubMed
    49. Caskey RC, Allukian M, Lind RC, Herdrich BJ, Xu J, Radu A, Mitchell ME, Liechty KW. Lentiviral-mediated over-expression of hyaluronan synthase-1 (HAS-1) decreases the cellular inflammatory response and results in regenerative wound repair. Cell Tissue Res. 2013 Jan; 351(1):117-25. PMID: 23149717.
      View in: PubMed
    50. Xu J, Wu W, Zhang L, Dorset-Martin W, Morris MW, Mitchell ME, Liechty KW. The role of microRNA-146a in the pathogenesis of the diabetic wound-healing impairment: correction with mesenchymal stem cell treatment. Diabetes. 2012 Nov; 61(11):2906-12. PMID: 22851573.
      View in: PubMed
    51. Zouein FA, Zgheib C, Liechty KW, Booz GW. Post-infarct biomaterials, left ventricular remodeling, and heart failure: is good good enough? Congest Heart Fail. 2012 Sep-Oct; 18(5):284-90. PMID: 22612796.
      View in: PubMed
    52. Brewer J, Liechty KW, Bofill JA. EXIT procedure: a report of the first three Mississippi cases. J Miss State Med Assoc. 2012 Apr; 53(4):104-8. PMID: 22803277.
      View in: PubMed
    53. Bermudez DM, Herdrich BJ, Xu J, Lind R, Beason DP, Mitchell ME, Soslowsky LJ, Liechty KW. Impaired biomechanical properties of diabetic skin implications in pathogenesis of diabetic wound complications. Am J Pathol. 2011 May; 178(5):2215-23. PMID: 21514435.
      View in: PubMed
    54. Bermudez DM, Canning DA, Liechty KW. Age and pro-inflammatory cytokine production: wound-healing implications for scar-formation and the timing of genital surgery in boys. J Pediatr Urol. 2011 Jun; 7(3):324-31. PMID: 21527214.
      View in: PubMed
    55. Danzer E, Zhang L, Radu A, Bebbington MW, Liechty KW, Adzick NS, Flake AW. Amniotic fluid levels of glial fibrillary acidic protein in fetal rats with retinoic acid induced myelomeningocele: a potential marker for spinal cord injury. Am J Obstet Gynecol. 2011 Feb; 204(2):178.e1-11. PMID: 21284970.
      View in: PubMed
    56. Caskey RC, Liechty KW. Multiple strategies must be pursued in the development of cellular therapies. Cytotherapy. 2011 Feb; 13(2):133-4. PMID: 21235294.
      View in: PubMed
    57. Volk SW, Wang Y, Mauldin EA, Liechty KW, Adams SL. Diminished type III collagen promotes myofibroblast differentiation and increases scar deposition in cutaneous wound healing. Cells Tissues Organs. 2011; 194(1):25-37. PMID: 21252470.
      View in: PubMed
    58. Bermudez DM, Xu J, Herdrich BJ, Radu A, Mitchell ME, Liechty KW. Inhibition of stromal cell-derived factor-1a further impairs diabetic wound healing. J Vasc Surg. 2011 Mar; 53(3):774-84. PMID: 21211927.
      View in: PubMed
    59. Herdrich BJ, Danzer E, Davey MG, Bermudez DM, Radu A, Zhang L, Zhang Z, Soslowsky LJ, Liechty KW. Fetal tendon wound size modulates wound gene expression and subsequent wound phenotype. Wound Repair Regen. 2010 Sep-Oct; 18(5):543-9. PMID: 20840524.
      View in: PubMed
    60. Roybal JL, Liechty KW, Hedrick HL, Bebbington MW, Johnson MP, Coleman BG, Adzick NS, Flake AW. Predicting the severity of congenital high airway obstruction syndrome. J Pediatr Surg. 2010 Aug; 45(8):1633-9. PMID: 20713212.
      View in: PubMed
    61. Grice EA, Snitkin ES, Yockey LJ, Bermudez DM, Liechty KW, Segre JA. Longitudinal shift in diabetic wound microbiota correlates with prolonged skin defense response. Proc Natl Acad Sci U S A. 2010 Aug 17; 107(33):14799-804. PMID: 20668241.
      View in: PubMed
    62. Herdrich BJ, Danzer E, Davey MG, Allukian M, Englefield V, Gorman JH, Gorman RC, Liechty KW. Regenerative healing following foetal myocardial infarction. Eur J Cardiothorac Surg. 2010 Dec; 38(6):691-8. PMID: 20452780.
      View in: PubMed
    63. Danzer E, Gerdes M, D'Agostino JA, Bernbaum J, Siegle J, Hoffman C, Rintoul NE, Liechty KW, Flake AW, Adzick NS, Hedrick HL. Prospective, interdisciplinary follow-up of children with prenatally diagnosed giant omphalocele: short-term neurodevelopmental outcome. J Pediatr Surg. 2010 Apr; 45(4):718-23. PMID: 20385277.
      View in: PubMed
    64. Liechty KW. Ex-utero intrapartum therapy. Semin Fetal Neonatal Med. 2010 Feb; 15(1):34-9. PMID: 19683972.
      View in: PubMed
    65. Wilson RD, Hedrick H, Flake AW, Johnson MP, Bebbington MW, Mann S, Rychik J, Liechty K, Adzick NS. Sacrococcygeal teratomas: prenatal surveillance, growth and pregnancy outcome. Fetal Diagn Ther. 2009; 25(1):15-20. PMID: 19122459.
      View in: PubMed
    66. Ricchetti ET, Reddy SC, Ansorge HL, Zgonis MH, Van Kleunen JP, Liechty KW, Soslowsky LJ, Beredjiklian PK. Effect of interleukin-10 overexpression on the properties of healing tendon in a murine patellar tendon model. J Hand Surg Am. 2008 Dec; 33(10):1843-52. PMID: 19084188.
      View in: PubMed
    67. Laje P, Wilson RD, Guttenberg M, Liechty KW. Survival in primary congenital pulmonary lymphangiectasia with hydrops fetalis. Fetal Diagn Ther. 2008; 24(3):225-9. PMID: 18753762.
      View in: PubMed
    68. Peranteau WH, Merchant AM, Hedrick HL, Liechty KW, Howell LJ, Flake AW, Wilson RD, Johnson MP, Bebbington MW, Adzick NS. Prenatal course and postnatal management of peripheral bronchial atresia: association with congenital cystic adenomatoid malformation of the lung. Fetal Diagn Ther. 2008; 24(3):190-6. PMID: 18753756.
      View in: PubMed
    69. Heaton TE, Liechty KW. Postnatal management of prenatally diagnosed abdominal masses and anomalies. Prenat Diagn. 2008 Jul; 28(7):656-66. PMID: 18324619.
      View in: PubMed
    70. Laje P, Liechty KW. Postnatal management and outcome of prenatally diagnosed lung lesions. Prenat Diagn. 2008 Jul; 28(7):612-8. PMID: 18330859.
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    71. Badillo AT, Zhang L, Liechty KW. Stromal progenitor cells promote leukocyte migration through production of stromal-derived growth factor 1alpha: a potential mechanism for stromal progenitor cell-mediated enhancement of cellular recruitment to wounds. J Pediatr Surg. 2008 Jun; 43(6):1128-33. PMID: 18558195.
      View in: PubMed
    72. Badillo AT, Hedrick HL, Wilson RD, Danzer E, Bebbington MW, Johnson MP, Liechty KW, Flake AW, Adzick NS. Prenatal ultrasonographic gastrointestinal abnormalities in fetuses with gastroschisis do not correlate with postnatal outcomes. J Pediatr Surg. 2008 Apr; 43(4):647-53. PMID: 18405710.
      View in: PubMed
    73. Tsai AY, Liechty KW, Hedrick HL, Bebbington M, Wilson RD, Johnson MP, Howell LJ, Flake AW, Adzick NS. Outcomes after postnatal resection of prenatally diagnosed asymptomatic cystic lung lesions. J Pediatr Surg. 2008 Mar; 43(3):513-7. PMID: 18358291.
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    74. Liechty KW, Flake AW. Pulmonary vascular malformations. Semin Pediatr Surg. 2008 Feb; 17(1):9-16. PMID: 18158137.
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    75. Peranteau WH, Zhang L, Muvarak N, Badillo AT, Radu A, Zoltick PW, Liechty KW. IL-10 overexpression decreases inflammatory mediators and promotes regenerative healing in an adult model of scar formation. J Invest Dermatol. 2008 Jul; 128(7):1852-60. PMID: 18200061.
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    76. Herdrich BJ, Lind RC, Liechty KW. Multipotent adult progenitor cells: their role in wound healing and the treatment of dermal wounds. Cytotherapy. 2008; 10(6):543-50. PMID: 18836914.
      View in: PubMed
    77. Ilagan JG, Wilson RD, Bebbington M, Johnson MP, Hedrick HL, Liechty KW, Adzick NS. Pregnancy outcomes following bipolar umbilical cord cauterization for selective termination in complicated monochorionic multiple gestations. Fetal Diagn Ther. 2008; 23(2):153-8. PMID: 18042995.
      View in: PubMed
    78. Badillo AT, Chung S, Zhang L, Zoltick P, Liechty KW. Lentiviral gene transfer of SDF-1alpha to wounds improves diabetic wound healing. J Surg Res. 2007 Nov; 143(1):35-42. PMID: 17950070.
      View in: PubMed
    79. Hedrick HL, Danzer E, Merchant AM, Bebbington MW, Zhao H, Flake AW, Johnson MP, Liechty KW, Howell LJ, Wilson RD, Adzick NS. Liver position and lung-to-head ratio for prediction of extracorporeal membrane oxygenation and survival in isolated left congenital diaphragmatic hernia. Am J Obstet Gynecol. 2007 10; 197(4):422.e1-4. PMID: 17904987.
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    80. Volk SW, Radu A, Zhang L, Liechty KW. Stromal progenitor cell therapy corrects the wound-healing defect in the ischemic rabbit ear model of chronic wound repair. Wound Repair Regen. 2007 Sep-Oct; 15(5):736-47. PMID: 17971020.
      View in: PubMed
    81. Peranteau WH, Wilson RD, Liechty KW, Johnson MP, Bebbington MW, Hedrick HL, Flake AW, Adzick NS. Effect of maternal betamethasone administration on prenatal congenital cystic adenomatoid malformation growth and fetal survival. Fetal Diagn Ther. 2007; 22(5):365-71. PMID: 17556826.
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    82. Badillo AT, Redden RA, Zhang L, Doolin EJ, Liechty KW. Treatment of diabetic wounds with fetal murine mesenchymal stromal cells enhances wound closure. Cell Tissue Res. 2007 Aug; 329(2):301-11. PMID: 17453245.
      View in: PubMed
    83. Shaaban AF, Kim HB, Gaur L, Liechty KW, Flake AW. Prenatal transplantation of cytokine-stimulated marrow improves early chimerism in a resistant strain combination but results in poor long-term engraftment. Exp Hematol. 2006 Sep; 34(9):1278-87. PMID: 16939821.
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    84. Badillo AT, Kreiger PA, Schmitz KR, Ernst LM, Kaiser LR, Liechty KW. Wilms' tumor arising within a mediastinal teratoma. J Pediatr Surg. 2006 Aug; 41(8):e1-5. PMID: 16863828.
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    85. Wilson RD, Hedrick HL, Liechty KW, Flake AW, Johnson MP, Bebbington M, Adzick NS. Cystic adenomatoid malformation of the lung: review of genetics, prenatal diagnosis, and in utero treatment. . 2006 Jan 15; 140(2):151-5. PMID: 16353256.
      View in: PubMed
    86. Liechty KW, Hedrick HL, Hubbard AM, Johnson MP, Wilson RD, Ruchelli ED, Howell LJ, Crombleholme TM, Flake AW, Adzick NS. Severe pulmonary hypoplasia associated with giant cervical teratomas. J Pediatr Surg. 2006 Jan; 41(1):230-3. PMID: 16410139.
      View in: PubMed
    87. Crombleholme TM, Coleman B, Hedrick H, Liechty K, Howell L, Flake AW, Johnson M, Adzick NS. Cystic adenomatoid malformation volume ratio predicts outcome in prenatally diagnosed cystic adenomatoid malformation of the lung. J Pediatr Surg. 2002 Mar; 37(3):331-8. PMID: 11877643.
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    88. Liechty KW, MacKenzie TC, Shaaban AF, Radu A, Moseley AM, Deans R, Marshak DR, Flake AW. Human mesenchymal stem cells engraft and demonstrate site-specific differentiation after in utero transplantation in sheep. Nat Med. 2000 Nov; 6(11):1282-6. PMID: 11062543.
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    89. Liechty KW, Kim HB, Adzick NS, Crombleholme TM. Fetal wound repair results in scar formation in interleukin-10-deficient mice in a syngeneic murine model of scarless fetal wound repair. J Pediatr Surg. 2000 Jun; 35(6):866-72; discussion 872-3. PMID: 10873028.
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    90. Liechty KW, Adzick NS, Crombleholme TM. Diminished interleukin 6 (IL-6) production during scarless human fetal wound repair. Cytokine. 2000 Jun; 12(6):671-6. PMID: 10843743.
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    91. Liechty KW, Crombleholme TM. Management of fetal airway obstruction. Semin Perinatol. 1999 Dec; 23(6):496-506. PMID: 10630545.
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    92. Liechty KW, Nesbit M, Herlyn M, Radu A, Adzick NS, Crombleholme TM. Adenoviral-mediated overexpression of platelet-derived growth factor-B corrects ischemic impaired wound healing. J Invest Dermatol. 1999 Sep; 113(3):375-83. PMID: 10469337.
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    93. Liechty KW, Crombleholme TM, Weiner S, Bernick B, Flake AW, Adzick NS. The ex utero intrapartum treatment procedure for a large fetal neck mass in a twin gestation. Obstet Gynecol. 1999 May; 93(5 Pt 2):824-5. PMID: 10912408.
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    94. Quinn TM, Sylvester KG, Kitano Y, Kitano Y, Liechty KW, Jarrett BP, Adzick NS, Flake AW. TGF-beta2 is increased after fetal tracheal occlusion. J Pediatr Surg. 1999 May; 34(5):701-4; discussion 704-5. PMID: 10359167.
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    95. Liechty KW, Crombleholme TM, Quinn TM, Cass DL, Flake AW, Adzick NS. Elevated platelet-derived growth factor-B in congenital cystic adenomatoid malformations requiring fetal resection. J Pediatr Surg. 1999 May; 34(5):805-9; discussion 809-10. PMID: 10359185.
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    96. Liechty KW, Sablich TJ, Adzick NS, Crombleholme TM. Recombinant adenoviral mediated gene transfer in ischemic impaired wound healing. Wound Repair Regen. 1999 May-Jun; 7(3):148-53. PMID: 10417750.
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    97. Cass DL, Quinn TM, Yang EY, Liechty KW, Crombleholme TM, Flake AW, Adzick NS. Increased cell proliferation and decreased apoptosis characterize congenital cystic adenomatoid malformation of the lung. J Pediatr Surg. 1998 Jul; 33(7):1043-6; discussion 1047. PMID: 9694091.
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    98. Kim HB, Shaaban AF, Yang EY, Liechty KW, Flake AW. Microchimerism and tolerance after in utero bone marrow transplantation in mice. J Surg Res. 1998 Jun; 77(1):1-5. PMID: 9698523.
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    99. Liechty KW, Crombleholme TM, Cass DL, Martin B, Adzick NS. Diminished interleukin-8 (IL-8) production in the fetal wound healing response. J Surg Res. 1998 Jun; 77(1):80-4. PMID: 9698538.
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    100. Liechty KW, Crombleholme TM, Flake AW, Morgan MA, Kurth CD, Hubbard AM, Adzick NS. Intrapartum airway management for giant fetal neck masses: the EXIT (ex utero intrapartum treatment) procedure. Am J Obstet Gynecol. 1997 Oct; 177(4):870-4. PMID: 9369836.
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    101. Schibler KR, Li Y, Ohls RK, Nye NC, Durham MC, White W, Liechty KW, Le T, Christensen RD. Possible mechanisms accounting for the growth factor independence of hematopoietic progenitors from umbilical cord blood. Blood. 1994 Dec 01; 84(11):3679-84. PMID: 7524747.
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    102. Schibler KR, Ohls RK, Le T, Liechty KW, Christensen RD. Effect of recombinant stem cell factor on clonogenic maturation and cycle status of human fetal hematopoietic progenitors. Pediatr Res. 1994 Mar; 35(3):303-6. PMID: 7514781.
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    103. Schibler KR, Liechty KW, White WL, Christensen RD. Production of granulocyte colony-stimulating factor in vitro by monocytes from preterm and term neonates. Blood. 1993 Oct 15; 82(8):2478-84. PMID: 7691262.
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    104. Schibler KR, Trautman MS, Liechty KW, White WL, Rothstein G, Christensen RD. Diminished transcription of interleukin-8 by monocytes from preterm neonates. J Leukoc Biol. 1993 Apr; 53(4):399-403. PMID: 8482920.
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    105. Liechty KW, Schibler KR, Ohls RK, Perkins SL, Christensen RD. The failure of newborn mice infected with Escherichia coli to accelerate neutrophil production correlates with their failure to increase transcripts for granulocyte colony-stimulating factor and interleukin-6. Biol Neonate. 1993; 64(5):331-40. PMID: 7507713.
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    106. Schibler KR, Liechty KW, White WL, Rothstein G, Christensen RD. Defective production of interleukin-6 by monocytes: a possible mechanism underlying several host defense deficiencies of neonates. Pediatr Res. 1992 Jan; 31(1):18-21. PMID: 1594325.
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    107. Christensen RD, Liechty KW, Koenig JM, Schibler KR, Ohls RK. Administration of erythropoietin to newborn rats results in diminished neutrophil production. Blood. 1991 Sep 01; 78(5):1241-6. PMID: 1878592.
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    108. Liechty KW, Koenig JM, Mitchell MD, Romero R, Christensen RD. Production of interleukin-6 by fetal and maternal cells in vivo during intraamniotic infection and in vitro after stimulation with interleukin-1. Pediatr Res. 1991 Jan; 29(1):1-4. PMID: 2000252.
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    109. Liechty KW, Christensen RD. In vivo effect of interleukin-6 on cycling status of hematopoietic progenitors from adults and neonates. Pediatr Res. 1990 Oct; 28(4):323-6. PMID: 2235128.
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    110. Gardner JD, Liechty KW, Christensen RD. Effects of interleukin-6 on fetal hematopoietic progenitors. Blood. 1990 Jun 01; 75(11):2150-5. PMID: 2346778.
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    111. Ohls RK, Liechty KW, Turner MC, Kimura R, Christensen RD. Erythroid "burst promoting" activity in serum of patients with the anemia of prematurity. J Pediatr. 1990 May; 116(5):786-9. PMID: 2184214.
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