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Laura Michelle Westrate

TitleResearch Associate
InstitutionUniversity of Colorado Boulder
DepartmentBiology-MCD Instruction

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Dunn EM, Billquist EJ, VanderStoep AL, Bax PG, Westrate LM, McLellan LK, Peterson SC, MacKeigan JP, Putzke AP. Dual Roles of Fer Kinase Are Required for Proper Hematopoiesis and Vascular Endothelium Organization during Zebrafish Development. Biology (Basel). 2017 Nov 23; 6(4). PMID: 29168762.
      View in: PubMed
    2. Lee JE, Westrate LM, Wu H, Page C, Voeltz GK. Multiple dynamin family members collaborate to drive mitochondrial division. Nature. 2016 12 01; 540(7631):139-143. PMID: 27798601.
      View in: PubMed
    3. Westrate LM, Lee JE, Prinz WA, Voeltz GK. Form follows function: the importance of endoplasmic reticulum shape. Annu Rev Biochem. 2015; 84:791-811. PMID: 25580528.
      View in: PubMed
    4. Westrate LM, Drocco JA, Martin KR, Hlavacek WS, MacKeigan JP. Mitochondrial morphological features are associated with fission and fusion events. PLoS One. 2014; 9(4):e95265. PMID: 24733410; PMCID: PMC3986258.
    5. Niemi NM, Sacoman JL, Westrate LM, Gaither LA, Lanning NJ, Martin KR, MacKeigan JP. The pseudophosphatase MK-STYX physically and genetically interacts with the mitochondrial phosphatase PTPMT1. PLoS One. 2014; 9(4):e93896. PMID: 24709986; PMCID: PMC3977970.
    6. Westrate LM, Sayfie AD, Burgenske DM, MacKeigan JP. Persistent mitochondrial hyperfusion promotes G2/M accumulation and caspase-dependent cell death. PLoS One. 2014; 9(3):e91911. PMID: 24632851; PMCID: PMC3954829.
    7. Niemi NM, Lanning NJ, Westrate LM, MacKeigan JP. Downregulation of the mitochondrial phosphatase PTPMT1 is sufficient to promote cancer cell death. PLoS One. 2013; 8(1):e53803. PMID: 23326511; PMCID: PMC3542197.
    8. Martin KR, Barua D, Kauffman AL, Westrate LM, Posner RG, Hlavacek WS, Mackeigan JP. Computational model for autophagic vesicle dynamics in single cells. Autophagy. 2013 Jan; 9(1):74-92. PMID: 23196898; PMCID: PMC3542220.
    9. Chavda S, Liu Y, Babu B, Davis R, Sielaff A, Ruprich J, Westrate L, Tronrud C, Ferguson A, Franks A, Tzou S, Adkins C, Rice T, Mackay H, Kluza J, Tahir SA, Lin S, Kiakos K, Bruce CD, Wilson WD, Hartley JA, Lee M. Hx, a novel fluorescent, minor groove and sequence specific recognition element: design, synthesis, and DNA binding properties of p-anisylbenzimidazole-imidazole/pyrrole-containing polyamides. Biochemistry. 2011 Apr 19; 50(15):3127-36. PMID: 21388229.
      View in: PubMed
    10. Babu B, Liu Y, Plaunt A, Riddering C, Ogilvie R, Westrate L, Davis R, Ferguson A, Mackay H, Rice T, Chavda S, Wilson D, Lin S, Kiakos K, Hartley JA, Lee M. Design, synthesis and DNA binding properties of orthogonally positioned diamino containing polyamide f-IPI. Biochem Biophys Res Commun. 2011 Jan 21; 404(3):848-52. PMID: 21185262.
      View in: PubMed
    11. Chavda S, Mulder K, Brown T, Mackay H, Babu B, Westrate L, Ferguson A, Lin S, Kiakos K, Ramos JP, Munde M, Wilson WD, Hartley JA, Lee M. DNA recognition: design, synthesis and biophysical characteristics of pyrrole(H) based polyamides. Med Chem. 2010 May; 6(3):150-8. PMID: 20632976.
      View in: PubMed
    12. Westrate L, Mackay H, Brown T, Nguyen B, Kluza J, Wilson WD, Lee M, Hartley JA. Effects of the N-terminal acylamido group of imidazole- and pyrrole-containing polyamides on DNA sequence specificity and binding affinity. Biochemistry. 2009 Jun 23; 48(24):5679-88. PMID: 19419200.
      View in: PubMed
    13. Mackay H, Brown T, Uthe PB, Westrate L, Sielaff A, Jones J, Lajiness JP, Kluza J, O'Hare C, Nguyen B, Davis Z, Bruce C, Wilson WD, Hartley JA, Lee M. Sequence specific and high affinity recognition of 5'-ACGCGT-3' by rationally designed pyrrole-imidazole H-pin polyamides: thermodynamic and structural studies. Bioorg Med Chem. 2008 Oct 15; 16(20):9145-53. PMID: 18819814; PMCID: PMC3813011.
    14. Brown T, Mackay H, Turlington M, Sutterfield A, Smith T, Sielaff A, Westrate L, Bruce C, Kluza J, O'Hare C, Nguyen B, Wilson WD, Hartley JA, Lee M. Modifying the N-terminus of polyamides: PyImPyIm has improved sequence specificity over f-ImPyIm. Bioorg Med Chem. 2008 May 01; 16(9):5266-76. PMID: 18353654.
      View in: PubMed
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