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Michael O Alberti

TitleAsst Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-Pathology
ORCID ORCID Icon0000-0003-4269-4701 Additional info

    Collapse Biography 
    Collapse education and training
    California Lutheran University, Thousand Oaks, CAB.S.05/2005Biochemistry & Molecular Biology
    University of Alabama at Birmingham, Birmingham, ALPh.D.07/2011Viral Gene Therapy
    University of Alabama at Birmingham, Birmingham, ALM.D.06/2013Medicine
    University of California, Los Angeles (UCLA), Los Angeles, CAResidency06/2016Clinical Pathology
    Washington University in St. Louis, St. Louis, MOFellowship06/2017Molecular Genetic Pathology
    Washington University in St. Louis, St. Louis, MOPostdoctoral Training06/2022Molecular Drivers of Myeloid Malignancies

    Collapse Research 
    Collapse research activities and funding
    ASPIRE     (JORDAN, CRAIG T)Jul 1, 2023 - Jun 30, 2025
    University of Colorado School of Medicine
    Targeting therapeutic vulnerabilities in myeloid pathogenesis
    Role: Co-Investigator
    K08HL159354     (ALBERTI, MICHAEL O)Jul 9, 2021 - Jun 30, 2026
    NIH
    Distinct roles of U2AF1 mutations in myelodysplastic syndrome pathogenesis
    Role: Principal Investigator
    EvansMDS Young Investigator Award     (ALBERTI, MICHAEL O)Jul 1, 2021 - Jun 30, 2024
    Edward P. Evans Foundation
    Deconvoluting the molecular mechanisms of MDS pathogenesis by mutant U2AF1
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Schreiber AR, Santos J, McMahon B, Buckner TW, Olson C, Alberti MO, Guimar?es-Young A, Knoeckel C, Broussard L, Aubrey M, Palmer BE, Weiss E, Connors GR, Brunner S, Wisell JA, Pacheco T, Aisner DL, Gutman JA. A Case of Fetal-Induced Graft-versus-Host Disease. N Engl J Med. 2023 Aug 17; 389(7):668-670. PMID: 37585636.
      View in: PubMed
    2. Wadugu BA, Nonavinkere Srivatsan S, Heard A, Alberti MO, Ndonwi M, Liu J, Grieb S, Bradley J, Shao J, Ahmed T, Shirai CL, Khanna A, Fei DL, Miller CA, Graubert TA, Walter MJ. U2af1 is a haplo-essential gene required for hematopoietic cancer cell survival in mice. J Clin Invest. 2021 11 01; 131(21). PMID: 34546980.
      View in: PubMed
    3. Kim SP, Srivatsan SN, Chavez M, Shirai CL, White BS, Ahmed T, Alberti MO, Shao J, Nunley R, White LS, Bednarski J, Pehrson JR, Walter MJ. Mutant U2AF1-induced alternative splicing of H2afy (macroH2A1) regulates B-lymphopoiesis in mice. Cell Rep. 2021 08 31; 36(9):109626. PMID: 34469727.
      View in: PubMed
    4. Jaiswal AK, Truong H, Tran TM, Lin TL, Casero D, Alberti MO, Rao DS. Focused CRISPR-Cas9 genetic screening reveals USO1 as a vulnerability in B-cell acute lymphoblastic leukemia. Sci Rep. 2021 06 23; 11(1):13158. PMID: 34162911.
      View in: PubMed
    5. Mullegama SV, Alberti MO, Au C, Li Y, Toy T, Tomasian V, Xian RR. Nucleic Acid Extraction from Human Biological Samples. Methods Mol Biol. 2019; 1897:359-383. PMID: 30539458.
      View in: PubMed
    6. Alberti MO, Srivatsan SN, Shao J, McNulty SN, Chang GS, Miller CA, Dunlap JB, Yang F, Press RD, Gao Q, Ding L, Heusel JW, Duncavage EJ, Walter MJ. Discriminating a common somatic ASXL1 mutation (c.1934dup; p.G646Wfs*12) from artifact in myeloid malignancies using NGS. Leukemia. 2018 08; 32(8):1874-1878. PMID: 29959414.
      View in: PubMed
    7. Fernando TR, Contreras JR, Zampini M, Rodriguez-Malave NI, Alberti MO, Anguiano J, Tran TM, Palanichamy JK, Gajeton J, Ung NM, Aros CJ, Waters EV, Casero D, Basso G, Pigazzi M, Rao DS. The lncRNA CASC15 regulates SOX4 expression in RUNX1-rearranged acute leukemia. Mol Cancer. 2017 07 19; 16(1):126. PMID: 28724437.
      View in: PubMed
    8. King JK, Ung NM, Paing MH, Contreras JR, Alberti MO, Fernando TR, Zhang K, Pellegrini M, Rao DS. Regulation of Marginal Zone B-Cell Differentiation by MicroRNA-146a. Front Immunol. 2016; 7:670. PMID: 28138326.
      View in: PubMed
    9. Albeiroti S, Alberti MO, Buggs V, Swartz G, Butch AW, Drees JC, Kelly KA. Evaluation of 2 Batched Pretreatment Systems for the Measurement of Whole Blood Tacrolimus on the ARCHITECT Immunoassay Analyzer. Lab Med. 2016 Nov; 47(4):268-274. PMID: 27474776.
      View in: PubMed
    10. Alberti MO, Hindler JA, Humphries RM. Performance of Etest for Antimicrobial Susceptibility Testing of Abiotrophia defectiva and Granulicatella Species. J Clin Microbiol. 2016 08; 54(8):2194-6. PMID: 27280419.
      View in: PubMed
    11. Alberti MO, Hindler JA, Humphries RM. Erratum for Alberti et al., Antimicrobial Susceptibilities of Abiotrophia defectiva, Granulicatella adiacens, and Granulicatella elegans. Antimicrob Agents Chemother. 2016 06; 60(6):3868. PMID: 27217443.
      View in: PubMed
    12. Rodr?guez-Malav? NI, Fernando TR, Patel PC, Contreras JR, Palanichamy JK, Tran TM, Anguiano J, Davoren MJ, Alberti MO, Pioli KT, Sandoval S, Crooks GM, Rao DS. BALR-6 regulates cell growth and cell survival in B-lymphoblastic leukemia. Mol Cancer. 2015 Dec 22; 14:214. PMID: 26694754.
      View in: PubMed
    13. Alberti MO, Hindler JA, Humphries RM. Antimicrobial Susceptibilities of Abiotrophia defectiva, Granulicatella adiacens, and Granulicatella elegans. Antimicrob Agents Chemother. 2015 Dec 14; 60(3):1411-20. PMID: 26666926.
      View in: PubMed
    14. Alberti MO, Drake TA, Song L. The pH of chemistry assays plays an important role in monoclonal immunoglobulin interferences. Pract Lab Med. 2015 Dec 01; 3:8-16. PMID: 28932804.
      View in: PubMed
    15. Alberti MO, Jones JJ, Miglietta R, Ding H, Bakshi RK, Edmonds TG, Kappes JC, Ochsenbauer C. Optimized Replicating Renilla Luciferase Reporter HIV-1 Utilizing Novel Internal Ribosome Entry Site Elements for Native Nef Expression and Function. AIDS Res Hum Retroviruses. 2015 Dec; 31(12):1278-96. PMID: 26101895.
      View in: PubMed
    16. Roth JC, Alberti MO, Ismail M, Lingas KT, Reese JS, Gerson SL. MGMT enrichment and second gene co-expression in hematopoietic progenitor cells using separate or dual-gene lentiviral vectors. Virus Res. 2015 Jan 22; 196:170-80. PMID: 25479595.
      View in: PubMed
    17. Alberti MO, Fukuchi AM, Kelly KA. Influence of serum separator tubes on mycophenolic acid concentrations determined by HPLC. Ther Drug Monit. 2014 Oct; 36(5):686-7. PMID: 24718269.
      View in: PubMed
    18. Woo JS, Alberti MO, Tirado CA. Childhood B-acute lymphoblastic leukemia: a genetic update. Exp Hematol Oncol. 2014; 3:16. PMID: 24949228.
      View in: PubMed
    19. Alberti MO, Deshane JS, Chaplin DD, Pereboeva L, Curiel DT, Roth JC. A myeloid cell-binding adenovirus efficiently targets gene transfer to the lung and escapes liver tropism. Gene Ther. 2013 Jul; 20(7):733-41. PMID: 23171918.
      View in: PubMed
    20. Alberti MO, Roth JC, Ismail M, Tsuruta Y, Abraham E, Pereboeva L, Gerson SL, Curiel DT. Derivation of a myeloid cell-binding adenovirus for gene therapy of inflammation. PLoS One. 2012; 7(5):e37812. PMID: 22624065.
      View in: PubMed
    21. Revie D, Alberti MO, Prichard JG, Kelley AS, Salahuddin SZ. Analysis of the 5'UTR of HCV genotype 3 grown in vitro in human B cells, T cells, and macrophages. Virol J. 2010 Jul 13; 7:155. PMID: 20626910.
      View in: PubMed
    22. Revie D, Alberti MO, Braich RS, Bayles D, Prichard JG, Salahuddin SZ. Discovery of significant variants containing large deletions in the 5'UTR of human hepatitis C virus (HCV). Virol J. 2006 Sep 29; 3:82. PMID: 17010198.
      View in: PubMed
    23. Revie D, Alberti MO, Braich RS, Chelyapov N, Bayles D, Prichard JG, Salahuddin SZ. Analysis of in vitro replicated human hepatitis C virus (HCV) for the determination of genotypes and quasispecies. Virol J. 2006 Sep 29; 3:81. PMID: 17010197.
      View in: PubMed
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