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Stanley J Szefler

TitleProfessor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-PEDS
Phone720/777-0985

    Collapse Research 
    Collapse research activities and funding
    UH3HL151297     (SZEFLER, STANLEY J)Sep 10, 2020 - Aug 31, 2027
    NIH
    Reducing Asthma Attacks in Disadvantaged School Children with Asthma
    Role: Principal Investigator

    UG3HL151297     (CICUTTO, LISA ;HUEBSCHMANN, AMY GROTELUESCHEN;SZEFLER, STANLEY J)Sep 10, 2020 - Aug 31, 2023
    NIH
    Reducing Asthma Attacks in Disadvantaged School Children with Asthma
    Role: Principal Investigator

    UG1HL139123     (SZEFLER, STANLEY J;WECHSLER, MICHAEL E)Sep 23, 2017 - Jun 30, 2024
    NIH
    Precision Interventions for Severe and/or Exacerbation Prone Asthma (PrecISE)
    Role: Co-Principal Investigator

    U10HL098075     (WECHSLER, MICHAEL E)Sep 30, 2009 - Jun 30, 2018
    NIH
    Clinical Centers for the NHLBI Asthma Network (AsthmaNet)
    Role: Co-Principal Investigator

    R21HL087811     (SZEFLER, STANLEY J)Sep 1, 2008 - Jun 30, 2011
    NIH
    Progression of Airway Obstruction in Childhood Asthma
    Role: Principal Investigator

    U01HL075416     (SZEFLER, STANLEY J)Sep 30, 2003 - Jun 30, 2012
    NIH
    CAMP Contiunation Study/Phase 3
    Role: Principal Investigator

    U10HL064288     (SZEFLER, STANLEY JAMES)Sep 30, 1999 - May 31, 2010
    NIH
    Childhood Asthma Research and Education Network: Denver Site
    Role: Principal Investigator

    U01HD037237     (SZEFLER, STANLEY J)Jan 1, 1999 - Dec 31, 2004
    NIH
    PEDIATRIC PHARMACOLOGY RESEARCH UNIT
    Role: Principal Investigator

    N01HR016048     (SZEFLER, STANLEY J)Sep 30, 1991 - Dec 31, 1999
    NIH/NHLBI
    CLINICAL CENTER FOR CAMP
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Stempel DA, Szefler SJ. Is the assessment of asthma treatment efficacy sufficiently comprehensive? J Allergy Clin Immunol. 2024 Mar; 153(3):629-636. PMID: 38135011.
      View in: PubMed
    2. De Keyser H, Vuong V, Kaye L, Anderson WC, Szefler S, Stempel DA. Reply to "Breath-taking compliance: Does lower adherence translate to inferiority?" J Allergy Clin Immunol Pract. 2023 12; 11(12):3813-3814. PMID: 38065642.
      View in: PubMed
    3. Kyler KE, Szefler SJ. Fifty Years of Unraveling the Clinical Pharmacology of Corticosteroids. J Pharm Sci. 2024 01; 113(1):47-54. PMID: 37844761.
      View in: PubMed
    4. Keyser HH, Brinton JT, Bothwell S, Camacho M, Kempe A, Szefler SJ. Encouraging adherence in adolescents with asthma using financial incentives: An RCT. Pediatr Pulmonol. 2023 10; 58(10):2823-2831. PMID: 37449768.
      View in: PubMed
    5. Papadopoulos NG, Szefler SJ, Bacharier LB, Maspero JF, Domingo C, Fiocchi A, Lee JK, Daizadeh N, Lederer DJ, Hardin M, Gall R, Djandji M, Siddiqui S, Jacob-Nara JA, Deniz Y, Rowe PJ. Assessment of dupilumab in children with moderate-to-severe type 2 asthma with or without evidence of allergic asthma. Allergy. 2023 08; 78(8):2157-2167. PMID: 37059696.
      View in: PubMed
    6. De Keyser H, Vuong V, Kaye L, Anderson WC, Szefler S, Stempel DA. Is Once Versus Twice Daily Dosing Better for Adherence in Asthma and Chronic Obstructive Pulmonary Disease? J Allergy Clin Immunol Pract. 2023 07; 11(7):2087-2093.e3. PMID: 37088377.
      View in: PubMed
    7. Busse WW, Szefler SJ. Digital health in difficult-to-treat severe asthma. Lancet Respir Med. 2023 07; 11(7):578-579. PMID: 36963416.
      View in: PubMed
    8. Anderson WC, Banzon TM, Chawes B, Papadopoulos NG, Phipatanakul W, Szefler SJ. Factors to Consider in Prescribing Asthma Biologic Therapies to Children. J Allergy Clin Immunol Pract. 2023 03; 11(3):693-701. PMID: 36646381.
      View in: PubMed
    9. Carr TF, Fajt ML, Kraft M, Phipatanakul W, Szefler SJ, Zeki AA, Peden DB, White SR. Treating asthma in the time of COVID. J Allergy Clin Immunol. 2023 04; 151(4):809-817. PMID: 36528110.
      View in: PubMed
    10. Stempel DA, Szefler SJ. Adding a Biologic to Asthma Therapy: The Role of Adherence in Selecting the Right Patient. J Allergy Clin Immunol Pract. 2022 11; 10(11):2949-2950. PMID: 36357048.
      View in: PubMed
    11. Szefler SJ, Roberts G, Rubin AS, Zielen S, Kuna P, Alpan O, Anzures-Cabrera J, Chen Q, Holweg CTJ, Kaminski J, Putnam WS, Matthews JG, Kamath N. Efficacy, safety, and tolerability of lebrikizumab in adolescent patients with uncontrolled asthma (ACOUSTICS). Clin Transl Allergy. 2022 Jul; 12(7):e12176. PMID: 35846226.
      View in: PubMed
    12. May KR, Oppenheimer JJ, Szefler SJ. Over-the-Counter Availability of Rescue Inhalers for Asthma. JAMA. 2022 07 12; 328(2):215. PMID: 35819430.
      View in: PubMed
    13. Kho A, Daumit GL, Truesdale KP, Brown A, Kilbourne AM, Ladapo J, Wali S, Cicutto L, Matthews AK, Smith JD, Davis PD, Schoenthaler A, Ogedegbe G, Islam N, Mills KT, He J, Watson KS, Winn RA, Stevens J, Huebschmann AG, Szefler SJ. The National Heart Lung and Blood Institute Disparities Elimination through Coordinated Interventions to Prevent and Control Heart and Lung Disease Alliance. Health Serv Res. 2022 06; 57 Suppl 1:20-31. PMID: 35383917.
      View in: PubMed
    14. Szefler SJ, Cicutto L, Brewer SE, Gleason M, McFarlane A, DeCamp LR, Brinton JT, Huebschmann AG. Applying dissemination and implementation research methods to translate a school-based asthma program. J Allergy Clin Immunol. 2022 09; 150(3):535-548. PMID: 35569568.
      View in: PubMed
    15. Abdel-Aal A, Lisspers K, Williams S, Adab P, Adams R, Agarwal D, Barnard A, Bouloukaki I, van Boven JFM, Chavannes N, Dickens AP, van Gemert F, Escarrer M, Haroon S, Kayongo A, Kirenga B, Kocks JWH, Kotz D, Newby C, McNulty C, Metting E, Moral L, Papadakis S, Pinnock H, Price D, Ryan D, Singh SJ, Correia de Sousa J, St?llberg B, Szefler SJ, Taylor SJC, Tsiligianni I, Turner A, Weller D, Yusuf O, Tabyshova AK, Jordan RE. Prioritising primary care respiratory research needs: results from the 2020 International Primary Care Respiratory Group (IPCRG) global e-Delphi exercise. NPJ Prim Care Respir Med. 2022 01 28; 32(1):6. PMID: 35091570.
      View in: PubMed
    16. Trivedi M, Pappalardo AA, Udoko M, Garg A, Phipatanakul W, Szefler SJ, Nyenhuis SM. Social Determinants of Health in Asthma Through the Life Course. J Allergy Clin Immunol Pract. 2022 04; 10(4):953-961. PMID: 35033702.
      View in: PubMed
    17. Georas SN, Wright RJ, Ivanova A, Israel E, LaVange LM, Akuthota P, Carr TF, Denlinger LC, Fajt ML, Kumar R, O'Neal WK, Phipatanakul W, Szefler SJ, Aronica MA, Bacharier LB, Burbank AJ, Castro M, Crotty Alexander L, Bamdad J, Cardet JC, Comhair SAA, Covar RA, DiMango EA, Erwin K, Erzurum SC, Fahy JV, Gaffin JM, Gaston B, Gerald LB, Hoffman EA, Holguin F, Jackson DJ, James J, Jarjour NN, Kenyon NJ, Khatri S, Kirwan JP, Kraft M, Krishnan JA, Liu AH, Liu MC, Marquis MA, Martinez F, Mey J, Moore WC, Moy JN, Ortega VE, Peden DB, Pennington E, Peters MC, Ross K, Sanchez M, Smith LJ, Sorkness RL, Wechsler ME, Wenzel SE, White SR, Zein J, Zeki AA, Noel P. The Precision Interventions for Severe and/or Exacerbation-Prone (PrecISE) Asthma Network: An overview of Network organization, procedures, and interventions. J Allergy Clin Immunol. 2022 02; 149(2):488-516.e9. PMID: 34848210.
      View in: PubMed
    18. Abrams EM, Jordan K, Szefler SJ. School Asthma Care During COVID-19: What We Have Learned and What We Are Learning. J Allergy Clin Immunol Pract. 2022 02; 10(2):453-459. PMID: 34848382.
      View in: PubMed
    19. Bush A, Fitzpatrick AM, Saglani S, Anderson WC, Szefler SJ. Difficult-to-Treat Asthma Management in School-Age Children. J Allergy Clin Immunol Pract. 2022 02; 10(2):359-375. PMID: 34838706.
      View in: PubMed
    20. Ortega VE, Daya M, Szefler SJ, Bleecker ER, Chinchilli VM, Phipatanakul W, Mauger D, Martinez FD, Herrera-Luis E, Pino-Yanes M, Hawkins GA, Ampleford EJ, Kunselman SJ, Cox C, Bacharier LB, Cabana MD, Cardet JC, Castro M, Denlinger LC, Eng C, Fitzpatrick AM, Holguin F, Hu D, Jackson DJ, Jarjour N, Kraft M, Krishnan JA, Lazarus SC, Lemanske RF, Lima JJ, Lugogo N, Mak A, Moore WC, Naureckas ET, Peters SP, Pongracic JA, Sajuthi SP, Seibold MA, Smith LJ, Solway J, Sorkness CA, Wenzel S, White SR, Burchard EG, Barnes K, Meyers DA, Israel E, Wechsler ME. Pharmacogenetic studies of long-acting beta agonist and inhaled corticosteroid responsiveness in randomised controlled trials of individuals of African descent with asthma. Lancet Child Adolesc Health. 2021 12; 5(12):862-872. PMID: 34762840.
      View in: PubMed
    21. Mosnaim GS, Stempel DA, Gonzalez C, Adams B, BenIsrael-Olive N, Gondalia R, Kaye L, Shalowitz M, Szefler S. Electronic medication monitoring versus self-reported use of inhaled corticosteroids and short-acting beta2-agonists in uncontrolled asthma. J Asthma. 2022 Oct; 59(10):2024-2027. PMID: 34699302.
      View in: PubMed
    22. Szefler SJ, Jerschow E, Yoo B, Janampally P, Pazwash H, Holweg CTJ, Hudes G. Response to Omalizumab in Black and White Patients with Allergic Asthma. J Allergy Clin Immunol Pract. 2021 11; 9(11):4021-4028. PMID: 34303017.
      View in: PubMed
    23. Udoko M, De Keyser H, Szefler SJ. Should children with asthma simply be treated as little adults? Ann Allergy Asthma Immunol. 2021 11; 127(5):520-521. PMID: 34260900.
      View in: PubMed
    24. Abrams EM, Szefler S. Ongoing asthma management in children during the COVID-19 pandemic: to step down or not to step down? Lancet Respir Med. 2021 08; 9(8):820-822. PMID: 34252377.
      View in: PubMed
    25. Federico MJ, Denlinger LC, Corren J, Szefler SJ, Fuhlbrigge AL. Exacerbation-Prone Asthma: A Biological Phenotype or a Social Construct. J Allergy Clin Immunol Pract. 2021 07; 9(7):2627-2634. PMID: 34051392.
      View in: PubMed
    26. Izadi N, Baraghoshi D, Curran-Everett D, Zeiger RS, Szefler SJ, Covar RA. Factors Associated with Persistence of Severe Asthma from Late Adolescence to Early Adulthood. Am J Respir Crit Care Med. 2021 May 24. PMID: 34029510.
      View in: PubMed
    27. Martin J, Pijnenburg MW, Roberts G, Pike KC, Petsky H, Chang AB, Szefler SJ, Gergen P, Vermeulen F, Vael R, Turner S. Does lung function change in the months after an asthma exacerbation in children? Pediatr Allergy Immunol. 2021 08; 32(6):1208-1216. PMID: 33721352.
      View in: PubMed
    28. Israel E, Denlinger LC, Bacharier LB, LaVange LM, Moore WC, Peters MC, Georas SN, Wright RJ, Mauger DT, Noel P, Akuthota P, Bach J, Bleecker ER, Cardet JC, Carr TF, Castro M, Cinelli A, Comhair SAA, Covar RA, Alexander LC, DiMango EA, Erzurum SC, Fahy JV, Fajt ML, Gaston BM, Hoffman EA, Holguin F, Jackson DJ, Jain S, Jarjour NN, Ji Y, Kenyon NJ, Kosorok MR, Kraft M, Krishnan JA, Kumar R, Liu AH, Liu MC, Ly NP, Marquis MA, Martinez FD, Moy JN, O'Neal WK, Ortega VE, Peden DB, Phipatanakul W, Ross K, Smith LJ, Szefler SJ, Teague WG, Tulchinsky AF, Vijayanand P, Wechsler ME, Wenzel SE, White SR, Zeki AA, Ivanova A. PrecISE: Precision Medicine in Severe Asthma: An adaptive platform trial with biomarker ascertainment. J Allergy Clin Immunol. 2021 05; 147(5):1594-1601. PMID: 33667479.
      View in: PubMed
    29. Mosnaim G, Safioti G, Brown R, DePietro M, Szefler SJ, Lang DM, Portnoy JM, Bukstein DA, Bacharier LB, Merchant RK. Digital Health Technology in Asthma: A Comprehensive Scoping Review. J Allergy Clin Immunol Pract. 2021 06; 9(6):2377-2398. PMID: 33652136.
      View in: PubMed
    30. Sheehan WJ, Paul IM, Mauger DT, Moy JN, Szefler SJ, Jackson DJ, Fitzpatrick AM, Cabana MD, Covar R, Robison RG, Phipatanakul W. Adherence rates during a randomized controlled trial evaluating the use of blinded acetaminophen and ibuprofen in children with asthma. Contemp Clin Trials. 2021 05; 104:106334. PMID: 33652129.
      View in: PubMed
    31. Anderson WC, Gondalia R, De Keyser HE, Kaye L, Szefler SJ, Stempel DA. Digital assessment of medication utilization by age and diagnosis of asthma or COPD. J Allergy Clin Immunol Pract. 2021 04; 9(4):1723-1725. PMID: 33212238.
      View in: PubMed
    32. Mosnaim GS, Stempel DA, Gonzalez C, Adams B, BenIsrael-Olive N, Gondalia R, Kaye L, Shalowitz M, Szefler S. The Impact of Patient Self-Monitoring Via Electronic Medication Monitor and Mobile App Plus Remote Clinician Feedback on Adherence to Inhaled Corticosteroids: A Randomized Controlled Trial. J Allergy Clin Immunol Pract. 2021 04; 9(4):1586-1594. PMID: 33212239.
      View in: PubMed
    33. Menzies-Gow A, Szefler SJ, Busse WW. The Relationship of Asthma Biologics to Remission for Asthma. J Allergy Clin Immunol Pract. 2021 03; 9(3):1090-1098. PMID: 33130146.
      View in: PubMed
    34. Lee LA, Pedersen S, Pascoe SJ, Szefler SJ, Lenney W. No dose effect observed with chronic fluticasone propionate on growth velocity in children. Pediatr Allergy Immunol. 2021 02; 32(2):377-381. PMID: 32966707.
      View in: PubMed
    35. Busse WW, Szefler SJ, Haselkorn T, Iqbal A, Ortiz B, Lanier BQ, Chipps BE. Possible Protective Effect of Omalizumab on Lung Function Decline in Patients Experiencing Asthma Exacerbations. J Allergy Clin Immunol Pract. 2021 03; 9(3):1201-1211. PMID: 33223095.
      View in: PubMed
    36. Ivanova A, Israel E, LaVange LM, Peters MC, Denlinger LC, Moore WC, Bacharier LB, Marquis MA, Gotman NM, Kosorok MR, Tomlinson C, Mauger DT, Georas SN, Wright RJ, Noel P, Rosner GL, Akuthota P, Billheimer D, Bleecker ER, Cardet JC, Castro M, DiMango EA, Erzurum SC, Fahy JV, Fajt ML, Gaston BM, Holguin F, Jain S, Kenyon NJ, Krishnan JA, Kraft M, Kumar R, Liu MC, Ly NP, Moy JN, Phipatanakul W, Ross K, Smith LJ, Szefler SJ, Teague WG, Wechsler ME, Wenzel SE, White SR. The precision interventions for severe and/or exacerbation-prone asthma (PrecISE) adaptive platform trial: statistical considerations. J Biopharm Stat. 2020 11 01; 30(6):1026-1037. PMID: 32941098.
      View in: PubMed
    37. De Keyser HH, Szefler S. Asthma attacks in children are always preceded by poor asthma control: myth or maxim? Breathe (Sheff). 2020 Sep; 16(3):200169. PMID: 33447278.
      View in: PubMed
    38. Kaplan A, Szefler SJ, Halpin DMG. Impact of comorbid conditions on asthmatic adults and children. NPJ Prim Care Respir Med. 2020 08 20; 30(1):36. PMID: 32820164.
      View in: PubMed
    39. Wang K, Verbakel JY, Oke J, Fleming-Nouri A, Harada N, Atsuta R, Fujisawa T, Kawayama T, Inoue H, Lazarus S, Szefler S, Martinez FD, Shaw D, Pavord ID, Thomas M. Using fractional exhaled nitric oxide to guide step-down treatment decisions in asthma: practical considerations. Eur Respir J. 2020 08; 56(2). PMID: 32820024.
      View in: PubMed
    40. Navanandan N, Hamlington KL, Mistry RD, Szefler SJ, Liu AH. Oscillometry for acute asthma in the pediatric emergency department: A feasibility study. Ann Allergy Asthma Immunol. 2020 11; 125(5):607-609. PMID: 32652127.
      View in: PubMed
    41. Fielding SS, Pijnenburg M, de Jongste J, Pike K, Roberts G, Petsky H, Chang AB, Fritsch M, Frischer T, Szefler SJ, Gergen P, Vermeulen F, Vael R, Turner SS. Does treatment guided by exhaled nitric oxide fraction improve outcomes in subgroups of children with asthma? Eur Respir J. 2020 05; 55(5). PMID: 32165403.
      View in: PubMed
    42. Wang K, Verbakel JY, Oke J, Fleming-Nouri A, Brewin J, Roberts N, Harada N, Atsuta R, Takahashi K, Mori K, Fujisawa T, Shirai T, Kawayama T, Inoue H, Lazarus S, Szefler S, Martinez F, Shaw D, Pavord ID, Thomas M. Using fractional exhaled nitric oxide to guide step-down treatment decisions in patients with asthma: a systematic review and individual patient data meta-analysis. Eur Respir J. 2020 05; 55(5). PMID: 32139458.
      View in: PubMed
    43. Abrams EM, Szefler SJ. COVID-19 and the impact of social determinants of health. Lancet Respir Med. 2020 07; 8(7):659-661. PMID: 32437646.
      View in: PubMed
    44. Szefler SJ, Goldstein S, Vogelberg C, Bensch GW, Given J, Jugovic B, Engel M, Moroni-Zentgraf PM, Sigmund R, Hamelmann EH. Forced Expiratory Flow (FEF25-75%) as a Clinical Endpoint in Children and Adolescents with Symptomatic Asthma Receiving Tiotropium: A Post Hoc Analysis. Pulm Ther. 2020 Dec; 6(2):151-158. PMID: 32399899.
      View in: PubMed
    45. Abrams EM, Szefler SJ. Managing Asthma during Coronavirus Disease-2019: An Example for Other Chronic Conditions in Children and Adolescents. J Pediatr. 2020 07; 222:221-226. PMID: 32330469.
      View in: PubMed
    46. Szefler SJ, Casale TB, Haselkorn T, Yoo B, Ortiz B, Kattan M, Busse WW. Treatment Benefit with Omalizumab in Children by Indicators of Asthma Severity. J Allergy Clin Immunol Pract. 2020 09; 8(8):2673-2680.e3. PMID: 32298853.
      View in: PubMed
    47. Federico MJ, McFarlane AE, Szefler SJ, Abrams EM. The Impact of Social Determinants of Health on Children with Asthma. J Allergy Clin Immunol Pract. 2020 06; 8(6):1808-1814. PMID: 32294541.
      View in: PubMed
    48. Halpin DMG, Hamelmann EH, Frith PA, Moroni-Zentgraf PM, van Hecke B, Unseld A, Kerstjens HAM, Szefler SJ. Comparative Responses in Lung Function Measurements with Tiotropium in Adolescents and Adults, and Across Asthma Severities: A Post Hoc Analysis. Pulm Ther. 2020 Jun; 6(1):131-140. PMID: 32180164.
      View in: PubMed
    49. Haselkorn T, Szefler SJ, Chipps BE, Bleecker ER, Harkins MS, Paknis B, Kianifard F, Ortiz B, Zeiger RS. Disease Burden and Long-Term Risk of Persistent Very Poorly Controlled Asthma: TENOR II. J Allergy Clin Immunol Pract. 2020 Jul - Aug; 8(7):2243-2253. PMID: 32173511.
      View in: PubMed
    50. Fitzpatrick AM, Bacharier LB, Jackson DJ, Szefler SJ, Beigelman A, Cabana M, Covar R, Guilbert T, Holguin F, Lemanske RF, Martinez FD, Morgan W, Phipatanakul W, Pongracic JA, Raissy HH, Zeiger RS, Mauger DT. Heterogeneity of Mild to Moderate Persistent Asthma in Children: Confirmation by Latent Class Analysis and Association with 1-Year Outcomes. J Allergy Clin Immunol Pract. 2020 09; 8(8):2617-2627.e4. PMID: 32156610.
      View in: PubMed
    51. Szefler SJ, Fitzgerald DA, Adachi Y, Doull IJ, Fischer GB, Fletcher M, Hong J, Garc?a-Marcos L, Pedersen S, ?strem A, Sly PD, Williams S, Winders T, Zar HJ, Bush A, Lenney W. A worldwide charter for all children with asthma. Pediatr Pulmonol. 2020 05; 55(5):1282-1292. PMID: 32142219.
      View in: PubMed
    52. Abrams EM, Becker AB, Szefler SJ. Paradigm Shift in Asthma Therapy for Adolescents: Should It Apply to Younger Children as Well? JAMA Pediatr. 2020 03 01; 174(3):227-228. PMID: 31904766.
      View in: PubMed
    53. De Keyser HEH, Kaye L, Anderson WC, Gondalia R, Theye B, Szefler SJ, Stempel DA. Electronic medication monitors help determine adherence subgroups in asthma. Respir Med. 2020 04; 164:105914. PMID: 32094102.
      View in: PubMed
    54. Szefler SJ. Update on the NAEPPCC Asthma Guidelines: The wait is over, or is it? J Allergy Clin Immunol. 2020 12; 146(6):1275-1280. PMID: 32004522.
      View in: PubMed
    55. Ross KR, Szefler SJ. Introducing telehealth and adherence monitoring to school-centered asthma management. Pediatr Pulmonol. 2020 03; 55(3):565-567. PMID: 31977164.
      View in: PubMed
    56. Fielding S, Pijnenburg M, de Jongste J, Pike K, Roberts G, Petsky H, Chang AB, Fritsch M, Frischer T, Szefler S, Gergen P, Vermeulen F, Vael R, Turner S. What is a clinically meaningful change in exhaled nitric oxide for children with asthma? Pediatr Pulmonol. 2020 03; 55(3):599-606. PMID: 31909561.
      View in: PubMed
    57. Menzies-Gow A, Bafadhel M, Busse WW, Casale TB, Kocks JWH, Pavord ID, Szefler SJ, Woodruff PG, de Giorgio-Miller A, Trudo F, Fageras M, Ambrose CS. An expert consensus framework for asthma remission as a treatment goal. J Allergy Clin Immunol. 2020 03; 145(3):757-765. PMID: 31866436.
      View in: PubMed
    58. Hamelmann E, von Mutius E, Bush A, Szefler SJ. Addressing the risk domain in the long-term management of pediatric asthma. Pediatr Allergy Immunol. 2020 04; 31(3):233-242. PMID: 31732983.
      View in: PubMed
    59. Hoch H, Kattan M, Szefler SJ. Challenges in managing difficult-to-treat asthma in children: Stop, look, and listen. Pediatr Pulmonol. 2020 03; 55(3):791-794. PMID: 31710161.
      View in: PubMed
    60. Anderson WC, Gondalia R, Hoch HE, Kaye L, Barrett M, Szefler SJ, Stempel DA. Assessing asthma control: comparison of electronic-recorded short-acting beta-agonist rescue use and self-reported use utilizing the asthma control test. J Asthma. 2021 02; 58(2):271-275. PMID: 31668103.
      View in: PubMed
    61. Fitzpatrick AM, Szefler SJ, Mauger DT, Phillips BR, Denlinger LC, Moore WC, Sorkness RL, Wenzel SE, Gergen PJ, Bleecker ER, Castro M, Erzurum SC, Fahy JV, Gaston BM, Israel E, Levy BD, Meyers DA, Teague WG, Bacharier LB, Ly NP, Phipatanakul W, Ross KR, Zein J, Jarjour NN. Development and initial validation of the Asthma Severity Scoring System (ASSESS). J Allergy Clin Immunol. 2020 01; 145(1):127-139. PMID: 31604088.
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    62. Szefler SJ. Legends of allergy and immunology: Donald Y. M. Leung. Allergy. 2020 03; 75(3):724-726. PMID: 31465550.
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    63. Wechsler ME, Szefler SJ, Ortega VE, Pongracic JA, Chinchilli V, Lima JJ, Krishnan JA, Kunselman SJ, Mauger D, Bleecker ER, Bacharier LB, Beigelman A, Benson M, Blake KV, Cabana MD, Cardet JC, Castro M, Chmiel JF, Covar R, Denlinger L, DiMango E, Fitzpatrick AM, Gentile D, Grossman N, Holguin F, Jackson DJ, Kumar H, Kraft M, LaForce CF, Lang J, Lazarus SC, Lemanske RF, Long D, Lugogo N, Martinez F, Meyers DA, Moore WC, Moy J, Naureckas E, Olin JT, Peters SP, Phipatanakul W, Que L, Raissy H, Robison RG, Ross K, Sheehan W, Smith LJ, Solway J, Sorkness CA, Sullivan-Vedder L, Wenzel S, White S, Israel E. Step-Up Therapy in Black Children and Adults with Poorly Controlled Asthma. N Engl J Med. 2019 09 26; 381(13):1227-1239. PMID: 31553835.
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    64. Stempel H, Federico MJ, Szefler SJ. Applying a biopsychosocial model to inner city asthma: Recent approaches to address pediatric asthma health disparities. Paediatr Respir Rev. 2019 Nov; 32:10-15. PMID: 31678039.
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    65. Hamelmann E, Szefler SJ, Lau S. Severe asthma in children and adolescents. Allergy. 2019 11; 74(11):2280-2282. PMID: 31074873.
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    66. Barnes PJ, Szefler SJ, Reddel HK, Chipps BE. Symptoms and perception of airway obstruction in asthmatic patients: Clinical implications for use of reliever medications. J Allergy Clin Immunol. 2019 11; 144(5):1180-1186. PMID: 31330221.
      View in: PubMed
    67. Graham LM, Kerstjens HAM, Vogelberg C, Hamelmann E, Szefler SJ, Pisternick-Ruf W, Engel M, El Azzi G, Unseld A, Foggs MB. Safety of tiotropium Respimat? in black or African-American patients with symptomatic asthma. Respir Med. 2019 08; 155:58-60. PMID: 31302579.
      View in: PubMed
    68. Vogelberg C, Szefler SJ, Vrijlandt EJLE, Boner AL, Engel M, El Azzi G, Vulcu SD, Moroni-Zentgraf PM, Eickmeier O, Hamelmann EH. Tiotropium add-on therapy is safe and?reduces seasonal worsening in paediatric?asthma patients. Eur Respir J. 2019 06; 53(6). PMID: 31097514.
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    131. Nyenhuis SM, Krishnan JA, Berry A, Calhoun WJ, Chinchilli VM, Engle L, Grossman N, Holguin F, Israel E, Kittles RA, Kraft M, Lazarus SC, Lehman EB, Mauger DT, Moy JN, Peters SP, Phipatanakul W, Smith LJ, Sumino K, Szefler SJ, Wechsler ME, Wenzel S, White SR, Ackerman SJ. Race is associated with differences in airway inflammation in patients with asthma. J Allergy Clin Immunol. 2017 Jul; 140(1):257-265.e11. PMID: 28069248.
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    137. Yang IV, Pedersen BS, Liu AH, O'Connor GT, Pillai D, Kattan M, Misiak RT, Gruchalla R, Szefler SJ, Khurana Hershey GK, Kercsmar C, Richards A, Stevens AD, Kolakowski CA, Makhija M, Sorkness CA, Krouse RZ, Visness C, Davidson EJ, Hennessy CE, Martin RJ, Togias A, Busse WW, Schwartz DA. The nasal methylome and childhood atopic asthma. J Allergy Clin Immunol. 2017 May; 139(5):1478-1488. PMID: 27745942.
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    139. Gleason M, Cicutto L, Haas-Howard C, Raleigh BM, Szefler SJ. Leveraging Partnerships: Families, Schools, and Providers Working Together to Improve Asthma Management. Curr Allergy Asthma Rep. 2016 10; 16(10):74. PMID: 27709456.
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    140. Spahn JD, Malka J, Szefler SJ. Current application of exhaled nitric oxide in clinical practice. J Allergy Clin Immunol. 2016 11; 138(5):1296-1298. PMID: 27664377.
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    141. Iribarren C, Rahmaoui A, Long AA, Szefler SJ, Bradley MS, Carrigan G, Eisner MD, Chen H, Omachi TA, Farkouh ME, Rothman KJ. Cardiovascular and cerebrovascular events among patients receiving omalizumab: Results from EXCELS, a prospective cohort study in moderate to severe asthma. J Allergy Clin Immunol. 2017 May; 139(5):1489-1495.e5. PMID: 27639934.
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    142. Lemanske RF, Kakumanu S, Shanovich K, Antos N, Cloutier MM, Mazyck D, Phipatanakul W, Schantz S, Szefler S, Vandlik R, Williams P. Creation and implementation of SAMPRO?: A?school-based asthma management program. J Allergy Clin Immunol. 2016 Sep; 138(3):711-723. PMID: 27596707.
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    143. Stempel DA, Szefler SJ, Pedersen S, Zeiger RS, Yeakey AM, Lee LA, Liu AH, Mitchell H, Kral KM, Raphiou IH, Prillaman BA, Buaron KS, Yun Kirby S, Pascoe SJ. Safety of Adding Salmeterol to Fluticasone Propionate in Children with Asthma. N Engl J Med. 2016 09 01; 375(9):840-9. PMID: 27579634.
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    144. Sheehan WJ, Mauger DT, Paul IM, Moy JN, Boehmer SJ, Szefler SJ, Fitzpatrick AM, Jackson DJ, Bacharier LB, Cabana MD, Covar R, Holguin F, Lemanske RF, Martinez FD, Pongracic JA, Beigelman A, Baxi SN, Benson M, Blake K, Chmiel JF, Daines CL, Daines MO, Gaffin JM, Gentile DA, Gower WA, Israel E, Kumar HV, Lang JE, Lazarus SC, Lima JJ, Ly N, Marbin J, Morgan WJ, Myers RE, Olin JT, Peters SP, Raissy HH, Robison RG, Ross K, Sorkness CA, Thyne SM, Wechsler ME, Phipatanakul W. Acetaminophen versus Ibuprofen in Young Children with Mild Persistent Asthma. N Engl J Med. 2016 Aug 18; 375(7):619-30. PMID: 27532828.
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    145. Liu AH, Anderson WC, Dutmer CM, Searing DA, Szefler SJ. Advances in asthma 2015: Across the lifespan. J Allergy Clin Immunol. 2016 08; 138(2):397-404. PMID: 27497278.
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    146. Liptzin DR, Gleason MC, Cicutto LC, Cleveland CL, Shocks DJ, White MK, Faino AV, Szefler SJ. Developing, Implementing, and Evaluating a School-Centered Asthma Program: Step-Up Asthma Program. J Allergy Clin Immunol Pract. 2016 Sep-Oct; 4(5):972-979.e1. PMID: 27283054.
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    147. Federico MJ, Hoch HE, Anderson WC, Spahn JD, Szefler SJ. Asthma Management for Children: Risk Identification and Prevention. Adv Pediatr. 2016 08; 63(1):103-26. PMID: 27426897.
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    148. McGeachie MJ, Yates KP, Zhou X, Guo F, Sternberg AL, Van Natta ML, Wise RA, Szefler SJ, Sharma S, Kho AT, Cho MH, Croteau-Chonka DC, Castaldi PJ, Jain G, Sanyal A, Zhan Y, Lajoie BR, Dekker J, Stamatoyannopoulos J, Covar RA, Zeiger RS, Adkinson NF, Williams PV, Kelly HW, Grasemann H, Vonk JM, Koppelman GH, Postma DS, Raby BA, Houston I, Lu Q, Fuhlbrigge AL, Tantisira KG, Silverman EK, Tonascia J, Weiss ST, Strunk RC. Patterns of Growth and Decline in Lung Function in Persistent Childhood Asthma. N Engl J Med. 2016 May 12; 374(19):1842-1852. PMID: 27168434.
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    149. Hamelmann E, Bateman ED, Vogelberg C, Szefler SJ, Vandewalker M, Moroni-Zentgraf P, Avis M, Unseld A, Engel M, Boner AL. Tiotropium add-on therapy in adolescents with moderate asthma: A?1-year randomized controlled trial. J Allergy Clin Immunol. 2016 08; 138(2):441-450.e8. PMID: 26960245.
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    150. Kraft M, Gerber AN, Szefler SJ, Wechsler ME. Introduction to the 58th Annual Thomas L. Petty Aspen Lung Conference: Asthma 2015: Mechanisms to Personalized Medicine. Ann Am Thorac Soc. 2016 Mar; 13 Suppl 1:S23-4. PMID: 27027947.
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    151. Yang IV, Pedersen BS, Liu AH, O'Connor GT, Teach SJ, Kattan M, Misiak RT, Gruchalla R, Steinbach SF, Szefler SJ, Gill MA, Calatroni A, David G, Hennessy CE, Davidson EJ, Gergen P, Togias A, Busse WW, Schwartz DA. DNA Methylation Changes in Nasal Epithelia Are Associated with Allergic Asthma in the Inner City. Ann Am Thorac Soc. 2016 Mar; 13 Suppl 1:S99-S100. PMID: 27027970.
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    152. Dunn R, Szefler SJ. Severe Asthma in Pediatric Patients. Pathophysiology and Unmet Needs. Ann Am Thorac Soc. 2016 Mar; 13 Suppl 1:S103-4. PMID: 27027942.
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    153. Dhami S, Nurmatov U, Agache I, Lau S, Muraro A, Jutel M, Roberts G, Akdis C, Bonini M, Calderon M, Casale T, Cavkaytar O, Cox L, Demoly P, Flood B, Hamelmann E, Izuhara K, Kalayci ?, Kleine-Tebbe J, Nieto A, Papadopoulos N, Pfaar O, Rosenwasser L, Ryan D, Schmidt-Weber C, Szefler S, Wahn U, van Wijk RG, Wilkinson J, Sheikh A. Allergen immunotherapy for allergic asthma: protocol for a systematic review. Clin Transl Allergy. 2015; 6:5. PMID: 26862389.
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    154. Cicutto L, Shocks D, Gleason M, Haas-Howard C, White M, Szefler SJ. Creating District Readiness for Implementing Evidence-Based School-Centered Asthma Programs: Denver Public Schools as a Case Study. NASN Sch Nurse. 2016 Mar; 31(2):112-8. PMID: 26822131.
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    155. Szefler SJ. Examining causes of the urban (inner city) asthma epidemic: Implementing new management strategies. Allergy Asthma Proc. 2016 Jan-Feb; 37(1):4-8. PMID: 26831839.
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    156. Bender BG, Krishnan JA, Chambers DA, Cloutier MM, Riekert KA, Rand CS, Schatz M, Thomson CC, Wilson SR, Apter A, Carson SS, George M, Gerald JK, Gerald L, Goss CH, Okelo SO, Mularski RA, Nguyen HQ, Patel MR, Szefler SJ, Weiss CH, Wilson KC, Freemer M. American Thoracic Society and National Heart, Lung, and Blood Institute Implementation Research Workshop Report. Ann Am Thorac Soc. 2015 Dec; 12(12):S213-21. PMID: 26653201.
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    157. Levy BD, Noel PJ, Freemer MM, Cloutier MM, Georas SN, Jarjour NN, Ober C, Woodruff PG, Barnes KC, Bender BG, Camargo CA, Chupp GL, Denlinger LC, Fahy JV, Fitzpatrick AM, Fuhlbrigge A, Gaston BM, Hartert TV, Kolls JK, Lynch SV, Moore WC, Morgan WJ, Nadeau KC, Ownby DR, Solway J, Szefler SJ, Wenzel SE, Wright RJ, Smith RA, Erzurum SC. Future Research Directions in Asthma. An NHLBI Working Group Report. Am J Respir Crit Care Med. 2015 Dec 01; 192(11):1366-72. PMID: 26305520.
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    158. Bacharier LB, Guilbert TW, Mauger DT, Boehmer S, Beigelman A, Fitzpatrick AM, Jackson DJ, Baxi SN, Benson M, Burnham CD, Cabana M, Castro M, Chmiel JF, Covar R, Daines M, Gaffin JM, Gentile DA, Holguin F, Israel E, Kelly HW, Lazarus SC, Lemanske RF, Ly N, Meade K, Morgan W, Moy J, Olin T, Peters SP, Phipatanakul W, Pongracic JA, Raissy HH, Ross K, Sheehan WJ, Sorkness C, Szefler SJ, Teague WG, Thyne S, Martinez FD. Early Administration of Azithromycin and Prevention of Severe Lower Respiratory Tract Illnesses in Preschool Children With a History of Such Illnesses: A Randomized Clinical Trial. JAMA. 2015 Nov 17; 314(19):2034-2044. PMID: 26575060.
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    159. Hoch HE, Szefler SJ. Intermittent steroid inhalation for the treatment of childhood asthma. Expert Rev Clin Immunol. 2016; 12(2):183-94. PMID: 26561351.
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    160. Teach SJ, Gill MA, Togias A, Sorkness CA, Arbes SJ, Calatroni A, Wildfire JJ, Gergen PJ, Cohen RT, Pongracic JA, Kercsmar CM, Khurana Hershey GK, Gruchalla RS, Liu AH, Zoratti EM, Kattan M, Grindle KA, Gern JE, Busse WW, Szefler SJ. Preseasonal treatment with either omalizumab or an inhaled corticosteroid boost to prevent fall asthma exacerbations. J Allergy Clin Immunol. 2015 Dec; 136(6):1476-1485. PMID: 26518090.
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    161. Vogelberg C, Moroni-Zentgraf P, Leonaviciute-Klimantaviciene M, Sigmund R, Hamelmann E, Engel M, Szefler S. Erratum to: A randomised dose-ranging study of tiotropium Respimat? in children with symptomatic asthma despite inhaled corticosteroids. Respir Res. 2015 Oct 20; 16:128. PMID: 26487277.
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    162. Dunn RM, Lehman E, Chinchilli VM, Martin RJ, Boushey HA, Israel E, Kraft M, Lazarus SC, Lemanske RF, Lugogo NL, Peters SP, Sorkness CA, Szefler S, Wechsler ME. Impact of Age and Sex on Response to Asthma Therapy. Am J Respir Crit Care Med. 2015 Sep 01; 192(5):551-8. PMID: 26068329.
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    163. Anderson WC, Szefler SJ. New and future strategies to improve asthma control in children. J Allergy Clin Immunol. 2015 Oct; 136(4):848-59. PMID: 26318072.
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    164. Reddel HK, Bateman ED, Becker A, Boulet LP, Cruz AA, Drazen JM, Haahtela T, Hurd SS, Inoue H, de Jongste JC, Lemanske RF, Levy ML, O'Byrne PM, Paggiaro P, Pedersen SE, Pizzichini E, Soto-Quiroz M, Szefler SJ, Wong GW, FitzGerald JM. A summary of the new GINA strategy: a roadmap to asthma control. Eur Respir J. 2015 Sep; 46(3):622-39. PMID: 26206872.
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    165. Brand PL, M?kel? MJ, Szefler SJ, Frischer T, Price D. Monitoring asthma in childhood: symptoms, exacerbations and quality of life. Eur Respir Rev. 2015 Jun; 24(136):187-93. PMID: 26028631.
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    166. Meltzer LJ, Faino A, Szefler SJ, Strand M, Gelfand EW, Beebe DW. Experimentally manipulated sleep duration in adolescents with asthma: Feasibility and preliminary findings. Pediatr Pulmonol. 2015 Dec; 50(12):1360-7. PMID: 25872769.
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    167. Teach SJ, Gergen PJ, Szefler SJ, Mitchell HE, Calatroni A, Wildfire J, Bloomberg GR, Kercsmar CM, Liu AH, Makhija MM, Matsui E, Morgan W, O'Connor G, Busse WW. Seasonal risk factors for asthma exacerbations among inner-city children. J Allergy Clin Immunol. 2015 Jun; 135(6):1465-73.e5. PMID: 25794658.
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    168. Gerald JK, Gerald LB, Vasquez MM, Morgan WJ, Boehmer SJ, Lemanske RF, Mauger DT, Strunk RC, Szefler SJ, Zeiger RS, Bacharier LB, Bade E, Covar RA, Guilbert TW, Heidarian-Raissy H, Kelly HW, Malka-Rais J, Sorkness CA, Taussig LM, Chinchilli VM, Martinez FD. Markers of Differential Response to Inhaled Corticosteroid Treatment Among Children with Mild Persistent Asthma. J Allergy Clin Immunol Pract. 2015 Jul-Aug; 3(4):540-6.e3. PMID: 25783161.
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    169. Yang IV, Pedersen BS, Liu A, O'Connor GT, Teach SJ, Kattan M, Misiak RT, Gruchalla R, Steinbach SF, Szefler SJ, Gill MA, Calatroni A, David G, Hennessy CE, Davidson EJ, Zhang W, Gergen P, Togias A, Busse WW, Schwartz DA. DNA methylation and childhood asthma in the inner city. J Allergy Clin Immunol. 2015 Jul; 136(1):69-80. PMID: 25769910.
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    170. Pijnenburg MW, Baraldi E, Brand PL, Carlsen KH, Eber E, Frischer T, Hedlin G, Kulkarni N, Lex C, M?kel? MJ, Mantzouranis E, Moeller A, Pavord I, Piacentini G, Price D, Rottier BL, Saglani S, Sly PD, Szefler SJ, Tonia T, Turner S, Wooler E, L?drup Carlsen KC. Monitoring asthma in children. Eur Respir J. 2015 Apr; 45(4):906-25. PMID: 25745042.
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    171. Israel E, Lasky-Su J, Markezich A, Damask A, Szefler SJ, Schuemann B, Klanderman B, Sylvia J, Kazani S, Wu R, Martinez F, Boushey HA, Chinchilli VM, Mauger D, Weiss ST, Tantisira KG. Genome-wide association study of short-acting ?2-agonists. A novel genome-wide significant locus on chromosome 2 near ASB3. Am J Respir Crit Care Med. 2015 Mar 01; 191(5):530-7. PMID: 25562107.
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    172. Vogelberg C, Moroni-Zentgraf P, Leonaviciute-Klimantaviciene M, Sigmund R, Hamelmann E, Engel M, Szefler S. A randomised dose-ranging study of tiotropium Respimat? in children with symptomatic asthma despite inhaled corticosteroids. Respir Res. 2015 Feb 07; 16:20. PMID: 25851298.
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    173. Zemanick ET, Wagner BD, Robertson CE, Stevens MJ, Szefler SJ, Accurso FJ, Sagel SD, Harris JK. Assessment of airway microbiota and inflammation in cystic fibrosis using multiple sampling methods. Ann Am Thorac Soc. 2015 Feb; 12(2):221-9. PMID: 25474078.
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    174. Szefler SJ. Advances in pediatric asthma in 2014: Moving toward a population health perspective. J Allergy Clin Immunol. 2015 Mar; 135(3):644-52. PMID: 25649079.
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    175. Szefler SJ. Monitoring and adherence in asthma management. Lancet Respir Med. 2015 Mar; 3(3):175-6. PMID: 25617214.
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    176. Wang Y, Tong C, Wang Z, Wang Z, Mauger D, Tantisira KG, Israel E, Szefler SJ, Chinchilli VM, Boushey HA, Lazarus SC, Lemanske RF, Wu R. Pharmacodynamic genome-wide association study identifies new responsive loci for glucocorticoid intervention in asthma. Pharmacogenomics J. 2015 Oct; 15(5):422-9. PMID: 25601762.
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    177. Cicutto L, Gleason M, Szefler SJ. Establishing school-centered asthma programs. J Allergy Clin Immunol. 2014 Dec; 134(6):1223-1230. PMID: 25482867.
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    178. Pijnenburg MW, Szefler S. Personalized medicine in children with asthma. Paediatr Respir Rev. 2015 Mar; 16(2):101-7. PMID: 25458797.
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    179. Long A, Rothman K, Chen H, Carrigan G, Szefler S. Reply: To PMID 24679845. J Allergy Clin Immunol. 2015 Jan; 135(1):289-90. PMID: 25441293.
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    180. Sharma S, Zhou X, Thibault DM, Himes BE, Liu A, Szefler SJ, Strunk R, Castro M, Hansel NN, Diette GB, Vonakis BM, Adkinson NF, Avila L, Soto-Quiros M, Barraza-Villareal A, Lemanske RF, Solway J, Krishnan J, White SR, Cheadle C, Berger AE, Fan J, Boorgula MP, Nicolae D, Gilliland F, Barnes K, London SJ, Martinez F, Ober C, Celed?n JC, Carey VJ, Weiss ST, Raby BA. A genome-wide survey of CD4(+) lymphocyte regulatory genetic variants identifies novel asthma genes. J Allergy Clin Immunol. 2014 Nov; 134(5):1153-62. PMID: 24934276.
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    181. Malka J, Mauger DT, Covar R, Rabinovitch N, Lemanske RF, Spahn JD, Strunk RC, Zeiger RS, Morgan WJ, Szefler SJ. Eczema and race as combined determinants for differential response to step-up asthma therapy. J Allergy Clin Immunol. 2014 Aug; 134(2):483-5. PMID: 24835502.
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    182. Green AW, Goldstein S, Szefler SJ, Wanderer A, Weinberger M. In lasting tribute: Elliot F. Ellis, MD, 1929-2014. J Allergy Clin Immunol. 2014 May; 133(5):1504-5. PMID: 24892145.
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    183. Szefler SJ, Chmiel JF, Fitzpatrick AM, Giacoia G, Green TP, Jackson DJ, Nielsen HC, Phipatanakul W, Raissy HH. Reply: To PMID 24290281. J Allergy Clin Immunol. 2014 Jun; 133(6):1776-7. PMID: 24786239.
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    184. Meltzer LJ, Ullrich M, Szefler SJ. Sleep duration, sleep hygiene, and insomnia in adolescents with asthma. J Allergy Clin Immunol Pract. 2014 Sep-Oct; 2(5):562-9. PMID: 25213049.
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    185. Beigelman A, Zeiger RS, Mauger D, Strunk RC, Jackson DJ, Martinez FD, Morgan WJ, Covar R, Szefler SJ, Taussig LM, Bacharier LB. The association between vitamin D status and the rate of exacerbations requiring oral corticosteroids in preschool children with recurrent wheezing. J Allergy Clin Immunol. 2014 May; 133(5):1489-92, 1492.e1-3. PMID: 24698320.
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    186. Long A, Rahmaoui A, Rothman KJ, Guinan E, Eisner M, Bradley MS, Iribarren C, Chen H, Carrigan G, Ros?n K, Szefler SJ. Incidence of malignancy in patients with moderate-to-severe asthma treated with or without omalizumab. J Allergy Clin Immunol. 2014 Sep; 134(3):560-567.e4. PMID: 24679845.
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    187. Szefler SJ. Advances in pediatric asthma in 2013: coordinating asthma care. J Allergy Clin Immunol. 2014 Mar; 133(3):654-61. PMID: 24581430.
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    188. Park HW, Dahlin A, Tse S, Duan QL, Schuemann B, Martinez FD, Peters SP, Szefler SJ, Lima JJ, Kubo M, Tamari M, Tantisira KG. Genetic predictors associated with improvement of asthma symptoms in response to inhaled corticosteroids. J Allergy Clin Immunol. 2014 Mar; 133(3):664-9.e5. PMID: 24486069.
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    189. Szefler SJ, Chmiel JF, Fitzpatrick AM, Giacoia G, Green TP, Jackson DJ, Nielsen HC, Phipatanakul W, Raissy HH. Asthma across the ages: knowledge gaps in childhood asthma. J Allergy Clin Immunol. 2014 Jan; 133(1):3-13; quiz 14. PMID: 24290281.
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    191. Rabinovitch N, Mauger DT, Reisdorph N, Covar R, Malka J, Lemanske RF, Morgan WJ, Guilbert TW, Zeiger RS, Bacharier LB, Szefler SJ. Predictors of asthma control and lung function responsiveness to step 3 therapy in children with uncontrolled asthma. J Allergy Clin Immunol. 2014 Feb; 133(2):350-6. PMID: 24084071.
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    192. Peters SP, Bleecker ER, Kunselman SJ, Icitovic N, Moore WC, Pascual R, Ameredes BT, Boushey HA, Calhoun WJ, Castro M, Cherniack RM, Craig T, Denlinger LC, Engle LL, Dimango EA, Israel E, Kraft M, Lazarus SC, Lemanske RF, Lugogo N, Martin RJ, Meyers DA, Ramsdell J, Sorkness CA, Sutherland ER, Wasserman SI, Walter MJ, Wechsler ME, Chinchilli VM, Szefler SJ. Predictors of response to tiotropium versus salmeterol in asthmatic adults. J Allergy Clin Immunol. 2013 Nov; 132(5):1068-1074.e1. PMID: 24084072.
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    193. Himes BE, Qiu W, Klanderman B, Ziniti J, Senter-Sylvia J, Szefler SJ, Lemanske RF, Zeiger RS, Strunk RC, Martinez FD, Boushey H, Chinchilli VM, Israel E, Mauger D, Koppelman GH, Nieuwenhuis MA, Postma DS, Vonk JM, Rafaels N, Hansel NN, Barnes K, Raby B, Tantisira KG, Weiss ST. ITGB5 and AGFG1 variants are associated with severity of airway responsiveness. BMC Med Genet. 2013 Aug 28; 14:86. PMID: 23984888.
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    194. Raissy HH, Kelly HW, Harkins M, Szefler SJ. Inhaled corticosteroids in lung diseases. Am J Respir Crit Care Med. 2013 Apr 15; 187(8):798-803. PMID: 23370915.
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    195. Li X, Hawkins GA, Ampleford EJ, Moore WC, Li H, Hastie AT, Howard TD, Boushey HA, Busse WW, Calhoun WJ, Castro M, Erzurum SC, Israel E, Lemanske RF, Szefler SJ, Wasserman SI, Wenzel SE, Peters SP, Meyers DA, Bleecker ER. Genome-wide association study identifies TH1 pathway genes associated with lung function in asthmatic patients. J Allergy Clin Immunol. 2013 Aug; 132(2):313-20.e15. PMID: 23541324.
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    196. Sorkness CA, Wildfire JJ, Calatroni A, Mitchell HE, Busse WW, O'Connor GT, Pongracic JA, Ross K, Gill MA, Kattan M, Morgan WJ, Teach SJ, Gergen PJ, Liu AH, Szefler SJ. Reassessment of omalizumab-dosing strategies and pharmacodynamics in inner-city children and adolescents. J Allergy Clin Immunol Pract. 2013 Mar; 1(2):163-71. PMID: 24565455.
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    197. Himes BE, Sheppard K, Berndt A, Leme AS, Myers RA, Gignoux CR, Levin AM, Gauderman WJ, Yang JJ, Mathias RA, Romieu I, Torgerson DG, Roth LA, Huntsman S, Eng C, Klanderman B, Ziniti J, Senter-Sylvia J, Szefler SJ, Lemanske RF, Zeiger RS, Strunk RC, Martinez FD, Boushey H, Chinchilli VM, Israel E, Mauger D, Koppelman GH, Postma DS, Nieuwenhuis MA, Vonk JM, Lima JJ, Irvin CG, Peters SP, Kubo M, Tamari M, Nakamura Y, Litonjua AA, Tantisira KG, Raby BA, Bleecker ER, Meyers DA, London SJ, Barnes KC, Gilliland FD, Williams LK, Burchard EG, Nicolae DL, Ober C, DeMeo DL, Silverman EK, Paigen B, Churchill G, Shapiro SD, Weiss ST. Integration of mouse and human genome-wide association data identifies KCNIP4 as an asthma gene. PLoS One. 2013; 8(2):e56179. PMID: 23457522.
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    198. Szefler SJ, Busse WW. The long-acting ?-adrenergic agonist controversy in asthma: troublesome times! J Allergy Clin Immunol. 2012 Dec; 130(6):1256-9. PMID: 23195524.
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    199. Szefler SJ. Advances in pediatric asthma in 2012: moving toward asthma prevention. J Allergy Clin Immunol. 2013 Jan; 131(1):36-46. PMID: 23199603.
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    200. Denlinger LC, Manthei DM, Seibold MA, Ahn K, Bleecker E, Boushey HA, Calhoun WJ, Castro M, Chinchili VM, Fahy JV, Hawkins GA, Icitovic N, Israel E, Jarjour NN, King T, Kraft M, Lazarus SC, Lehman E, Martin RJ, Meyers DA, Peters SP, Sheerar D, Shi L, Sutherland ER, Szefler SJ, Wechsler ME, Sorkness CA, Lemanske RF. P2X7-regulated protection from exacerbations and loss of control is independent of asthma maintenance therapy. Am J Respir Crit Care Med. 2013 Jan 01; 187(1):28-33. PMID: 23144325.
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    201. Szefler SJ, Carlsson LG, Uryniak T, Baker JW. Budesonide inhalation suspension versus montelukast in children aged 2 to 4 years with mild persistent asthma. J Allergy Clin Immunol Pract. 2013 Jan; 1(1):58-64. PMID: 24229823.
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    202. Tamesis GP, Covar RA, Strand M, Liu AH, Szefler SJ, Klinnert MD. Predictors for asthma at age 7 years for low-income children enrolled in the Childhood Asthma Prevention Study. J Pediatr. 2013 Mar; 162(3):536-542.e2. PMID: 23036483.
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    203. Chipps BE, Zeiger RS, Dorenbaum A, Borish L, Wenzel SE, Miller DP, Hayden ML, Bleecker ER, Simons FE, Szefler SJ, Weiss ST, Haselkorn T. Assessment of asthma control and asthma exacerbations in the epidemiology and natural history of asthma: outcomes and treatment regimens (TENOR) observational cohort. Curr Respir Care Rep. 2012 Dec; 1(4):259-269. PMID: 23136642.
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    204. Calhoun WJ, Ameredes BT, King TS, Icitovic N, Bleecker ER, Castro M, Cherniack RM, Chinchilli VM, Craig T, Denlinger L, DiMango EA, Engle LL, Fahy JV, Grant JA, Israel E, Jarjour N, Kazani SD, Kraft M, Kunselman SJ, Lazarus SC, Lemanske RF, Lugogo N, Martin RJ, Meyers DA, Moore WC, Pascual R, Peters SP, Ramsdell J, Sorkness CA, Sutherland ER, Szefler SJ, Wasserman SI, Walter MJ, Wechsler ME, Boushey HA. Comparison of physician-, biomarker-, and symptom-based strategies for adjustment of inhaled corticosteroid therapy in adults with asthma: the BASALT randomized controlled trial. JAMA. 2012 Sep 12; 308(10):987-97. PMID: 22968888.
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    205. Szefler SJ. Early asthma: stepping closer to primary prevention. J Allergy Clin Immunol. 2012 Aug; 130(2):308-10. PMID: 22846745.
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    207. Papadopoulos NG, Arakawa H, Carlsen KH, Custovic A, Gern J, Lemanske R, Le Souef P, M?kel? M, Roberts G, Wong G, Zar H, Akdis CA, Bacharier LB, Baraldi E, van Bever HP, de Blic J, Boner A, Burks W, Casale TB, Castro-Rodriguez JA, Chen YZ, El-Gamal YM, Everard ML, Frischer T, Geller M, Gereda J, Goh DY, Guilbert TW, Hedlin G, Heymann PW, Hong SJ, Hossny EM, Huang JL, Jackson DJ, de Jongste JC, Kalayci O, A?t-Khaled N, Kling S, Kuna P, Lau S, Ledford DK, Lee SI, Liu AH, Lockey RF, L?drup-Carlsen K, L?tvall J, Morikawa A, Nieto A, Paramesh H, Pawankar R, Pohunek P, Pongracic J, Price D, Robertson C, Rosario N, Rossenwasser LJ, Sly PD, Stein R, Stick S, Szefler S, Taussig LM, Valovirta E, Vichyanond P, Wallace D, Weinberg E, Wennergren G, Wildhaber J, Zeiger RS. International consensus on (ICON) pediatric asthma. Allergy. 2012 Aug; 67(8):976-97. PMID: 22702533.
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    208. Chipps BE, Zeiger RS, Borish L, Wenzel SE, Yegin A, Hayden ML, Miller DP, Bleecker ER, Simons FE, Szefler SJ, Weiss ST, Haselkorn T. Key findings and clinical implications from The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) study. J Allergy Clin Immunol. 2012 Aug; 130(2):332-42.e10. PMID: 22694932.
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    209. Szefler SJ, Chinchilli VM, Israel E, Denlinger LC, Lemanske RF, Calhoun W, Peters SP. Key observations from the NHLBI Asthma Clinical Research Network. Thorax. 2012 May; 67(5):450-5. PMID: 22514237.
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    210. Tantisira KG, Damask A, Szefler SJ, Schuemann B, Markezich A, Su J, Klanderman B, Sylvia J, Wu R, Martinez F, Boushey HA, Chinchilli VM, Mauger D, Weiss ST, Israel E. Genome-wide association identifies the T gene as a novel asthma pharmacogenetic locus. Am J Respir Crit Care Med. 2012 Jun 15; 185(12):1286-91. PMID: 22538805.
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    211. Szefler SJ, Wenzel S, Brown R, Erzurum SC, Fahy JV, Hamilton RG, Hunt JF, Kita H, Liu AH, Panettieri RA, Schleimer RP, Minnicozzi M. Asthma outcomes: biomarkers. J Allergy Clin Immunol. 2012 Mar; 129(3 Suppl):S9-23. PMID: 22386512.
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    212. Zeiger RS, Yegin A, Simons FE, Haselkorn T, Rasouliyan L, Szefler SJ, Chipps BE. Evaluation of the National Heart, Lung, and Blood Institute guidelines impairment domain for classifying asthma control and predicting asthma exacerbations. Ann Allergy Asthma Immunol. 2012 Feb; 108(2):81-7. PMID: 22289725.
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    213. Wildfire JJ, Gergen PJ, Sorkness CA, Mitchell HE, Calatroni A, Kattan M, Szefler SJ, Teach SJ, Bloomberg GR, Wood RA, Liu AH, Pongracic JA, Chmiel JF, Conroy K, Rivera-Sanchez Y, Busse WW, Morgan WJ. Development and validation of the Composite Asthma Severity Index--an outcome measure for use in children and adolescents. J Allergy Clin Immunol. 2012 Mar; 129(3):694-701. PMID: 22244599.
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    214. Szefler SJ. Advances in pediatric asthma in 2011: moving forward. J Allergy Clin Immunol. 2012 Jan; 129(1):60-8. PMID: 22196525.
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    215. Zeiger RS, Mauger D, Bacharier LB, Guilbert TW, Martinez FD, Lemanske RF, Strunk RC, Covar R, Szefler SJ, Boehmer S, Jackson DJ, Sorkness CA, Gern JE, Kelly HW, Friedman NJ, Mellon MH, Schatz M, Morgan WJ, Chinchilli VM, Raissy HH, Bade E, Malka-Rais J, Beigelman A, Taussig LM. Daily or intermittent budesonide in preschool children with recurrent wheezing. N Engl J Med. 2011 Nov 24; 365(21):1990-2001. PMID: 22111718.
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    216. Krishnan JA, Bender BG, Wamboldt FS, Szefler SJ, Adkinson NF, Zeiger RS, Wise RA, Bilderback AL, Rand CS. Adherence to inhaled corticosteroids: an ancillary study of the Childhood Asthma Management Program clinical trial. J Allergy Clin Immunol. 2012 Jan; 129(1):112-8. PMID: 22104610.
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    217. Szefler SJ, Busse WW. Adding LABAs to inhaled glucocorticoids for asthma. N Engl J Med. 2011 09 29; 365(13):1260-1; author reply 1261. PMID: 21991913.
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    218. Tantisira KG, Lasky-Su J, Harada M, Murphy A, Litonjua AA, Himes BE, Lange C, Lazarus R, Sylvia J, Klanderman B, Duan QL, Qiu W, Hirota T, Martinez FD, Mauger D, Sorkness C, Szefler S, Lazarus SC, Lemanske RF, Peters SP, Lima JJ, Nakamura Y, Tamari M, Weiss ST. Genomewide association between GLCCI1 and response to glucocorticoid therapy in asthma. N Engl J Med. 2011 Sep 29; 365(13):1173-83. PMID: 21991891.
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    219. Szefler SJ. Is it time to revise the asthma guidelines? J Allergy Clin Immunol. 2011 Nov; 128(5):937-8. PMID: 21943941.
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    220. Szefler SJ. Personalised medicine for asthma management in pregnancy. Lancet. 2011 Sep 10; 378(9795):963-4. PMID: 21907846.
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    221. Horner CC, Mauger D, Strunk RC, Graber NJ, Lemanske RF, Sorkness CA, Szefler SJ, Zeiger RS, Taussig LM, Bacharier LB. Most nocturnal asthma symptoms occur outside of exacerbations and associate with morbidity. J Allergy Clin Immunol. 2011 Nov; 128(5):977-82.e1-2. PMID: 21855126.
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    222. Wu R, Tong C, Wang Z, Mauger D, Tantisira K, Szefler SJ, Chinchilli VM, Israel E. A conceptual framework for pharmacodynamic genome-wide association studies in pharmacogenomics. Drug Discov Today. 2011 Oct; 16(19-20):884-90. PMID: 21920452.
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    223. Szefler SJ, Dakhama A. New insights into asthma pathogenesis and treatment. Curr Opin Immunol. 2011 Dec; 23(6):801-7. PMID: 21840186.
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    224. Guilbert TW, Mauger DT, Allen DB, Zeiger RS, Lemanske RF, Szefler SJ, Strunk RC, Bacharier LB, Covar R, Sorkness CA, Taussig LM, Martinez FD. Growth of preschool children at high risk for asthma 2 years after discontinuation of fluticasone. J Allergy Clin Immunol. 2011 Nov; 128(5):956-63.e1-7. PMID: 21820163.
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    225. Szefler SJ. Advancing asthma care: the glass is only half full! J Allergy Clin Immunol. 2011 Sep; 128(3):485-94. PMID: 21798579.
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    226. Szefler SJ, Zeiger RS, Haselkorn T, Mink DR, Kamath TV, Fish JE, Chipps BE. Economic burden of impairment in children with severe or difficult-to-treat asthma. Ann Allergy Asthma Immunol. 2011 Aug; 107(2):110-119.e1. PMID: 21802018.
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    227. Busse WW, Morgan WJ, Gergen PJ, Mitchell HE, Gern JE, Liu AH, Gruchalla RS, Kattan M, Teach SJ, Pongracic JA, Chmiel JF, Steinbach SF, Calatroni A, Togias A, Thompson KM, Szefler SJ, Sorkness CA. Randomized trial of omalizumab (anti-IgE) for asthma in inner-city children. N Engl J Med. 2011 Mar 17; 364(11):1005-15. PMID: 21410369.
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    228. Martinez FD, Chinchilli VM, Morgan WJ, Boehmer SJ, Lemanske RF, Mauger DT, Strunk RC, Szefler SJ, Zeiger RS, Bacharier LB, Bade E, Covar RA, Friedman NJ, Guilbert TW, Heidarian-Raissy H, Kelly HW, Malka-Rais J, Mellon MH, Sorkness CA, Taussig L. Use of beclomethasone dipropionate as rescue treatment for children with mild persistent asthma (TREXA): a randomised, double-blind, placebo-controlled trial. Lancet. 2011 Feb 19; 377(9766):650-7. PMID: 21324520.
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    229. Sharma S, Murphy A, Howrylak J, Himes B, Cho MH, Chu JH, Hunninghake GM, Fuhlbrigge A, Klanderman B, Ziniti J, Senter-Sylvia J, Liu A, Szefler SJ, Strunk R, Castro M, Hansel NN, Diette GB, Vonakis BM, Adkinson NF, Carey VJ, Raby BA. The impact of self-identified race on epidemiologic studies of gene expression. Genet Epidemiol. 2011 Feb; 35(2):93-101. PMID: 21254216.
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    230. Wang L, Hollenbeak CS, Mauger DT, Zeiger RS, Paul IM, Sorkness CA, Lemanske RF, Martinez FD, Strunk RC, Szefler SJ, Taussig LM. Cost-effectiveness analysis of fluticasone versus montelukast in children with mild-to-moderate persistent asthma in the Pediatric Asthma Controller Trial. J Allergy Clin Immunol. 2011 Jan; 127(1):161-6, 166.e1. PMID: 21211651.
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    231. Szefler SJ. Advances in pediatric asthma in 2010: addressing the major issues. J Allergy Clin Immunol. 2011 Jan; 127(1):102-15. PMID: 21211645.
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    232. Haselkorn T, Szefler SJ, Simons FE, Zeiger RS, Mink DR, Chipps BE, Borish L, Wong DA. Allergy, total serum immunoglobulin E, and airflow in children and adolescents in TENOR. Pediatr Allergy Immunol. 2010 Dec; 21(8):1157-65. PMID: 20444153.
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    233. Szefler SJ. Defining asthma phenotypes: focusing the picture. J Allergy Clin Immunol. 2010 Nov; 126(5):939-40. PMID: 21050941.
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    234. Sutherland ER, King TS, Icitovic N, Ameredes BT, Bleecker E, Boushey HA, Calhoun WJ, Castro M, Cherniack RM, Chinchilli VM, Craig TJ, Denlinger L, DiMango EA, Fahy JV, Israel E, Jarjour N, Kraft M, Lazarus SC, Lemanske RF, Peters SP, Ramsdell J, Sorkness CA, Szefler SJ, Walter MJ, Wasserman SI, Wechsler ME, Chu HW, Martin RJ. A trial of clarithromycin for the treatment of suboptimally controlled asthma. J Allergy Clin Immunol. 2010 Oct; 126(4):747-53. PMID: 20920764.
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    235. Peters SP, Kunselman SJ, Icitovic N, Moore WC, Pascual R, Ameredes BT, Boushey HA, Calhoun WJ, Castro M, Cherniack RM, Craig T, Denlinger L, Engle LL, DiMango EA, Fahy JV, Israel E, Jarjour N, Kazani SD, Kraft M, Lazarus SC, Lemanske RF, Lugogo N, Martin RJ, Meyers DA, Ramsdell J, Sorkness CA, Sutherland ER, Szefler SJ, Wasserman SI, Walter MJ, Wechsler ME, Chinchilli VM, Bleecker ER. Tiotropium bromide step-up therapy for adults with uncontrolled asthma. N Engl J Med. 2010 Oct 28; 363(18):1715-26. PMID: 20979471.
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    236. Murphy A, Chu JH, Xu M, Carey VJ, Lazarus R, Liu A, Szefler SJ, Strunk R, Demuth K, Castro M, Hansel NN, Diette GB, Vonakis BM, Adkinson NF, Klanderman BJ, Senter-Sylvia J, Ziniti J, Lange C, Pastinen T, Raby BA. Mapping of numerous disease-associated expression polymorphisms in primary peripheral blood CD4+ lymphocytes. Hum Mol Genet. 2010 Dec 01; 19(23):4745-57. PMID: 20833654.
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    237. Rabinovitch N, Graber NJ, Chinchilli VM, Sorkness CA, Zeiger RS, Strunk RC, Bacharier LB, Martinez FD, Szefler SJ. Urinary leukotriene E4/exhaled nitric oxide ratio and montelukast response in childhood asthma. J Allergy Clin Immunol. 2010 Sep; 126(3):545-51.e1-4. PMID: 20816189.
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    238. Leung DY, Szefler SJ. In utero smoke (IUS) exposure has been associated with increased prevalence of asthma and reduced lung function in healthy children. J Allergy Clin Immunol. 2010 Sep; 126(3):481-2. PMID: 20816183.
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    239. Simon MR, Chinchilli VM, Phillips BR, Sorkness CA, Lemanske RF, Szefler SJ, Taussig L, Bacharier LB, Morgan W. Forced expiratory flow between 25% and 75% of vital capacity and FEV1/forced vital capacity ratio in relation to clinical and physiological parameters in asthmatic children with normal FEV1 values. J Allergy Clin Immunol. 2010 Sep; 126(3):527-34.e1-8. PMID: 20638110.
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    240. Covar R, Gleason M, Macomber B, Stewart L, Szefler P, Engelhardt K, Murphy J, Liu A, Wood S, DeMichele S, Gelfand EW, Szefler SJ. Impact of a novel nutritional formula on asthma control and biomarkers of allergic airway inflammation in children. Clin Exp Allergy. 2010 Aug; 40(8):1163-74. PMID: 20545703.
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    241. Lemanske RF, Mauger DT, Sorkness CA, Jackson DJ, Boehmer SJ, Martinez FD, Strunk RC, Szefler SJ, Zeiger RS, Bacharier LB, Covar RA, Guilbert TW, Larsen G, Morgan WJ, Moss MH, Spahn JD, Taussig LM. Step-up therapy for children with uncontrolled asthma receiving inhaled corticosteroids. N Engl J Med. 2010 Mar 18; 362(11):975-85. PMID: 20197425.
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    242. Szefler SJ, Gergen PJ, Mitchell H, Morgan W. Achieving asthma control in the inner city: do the National Institutes of Health Asthma Guidelines really work? J Allergy Clin Immunol. 2010 Mar; 125(3):521-6; quiz 527-8. PMID: 20226288.
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    243. Kattan M, Kumar R, Bloomberg GR, Mitchell HE, Calatroni A, Gergen PJ, Kercsmar CM, Visness CM, Matsui EC, Steinbach SF, Szefler SJ, Sorkness CA, Morgan WJ, Teach SJ, Gan VN. Asthma control, adiposity, and adipokines among inner-city adolescents. J Allergy Clin Immunol. 2010 Mar; 125(3):584-92. PMID: 20226295.
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    244. Covar RA, Strunk R, Zeiger RS, Wilson LA, Liu AH, Weiss S, Tonascia J, Spahn JD, Szefler SJ. Predictors of remitting, periodic, and persistent childhood asthma. J Allergy Clin Immunol. 2010 Feb; 125(2):359-366.e3. PMID: 20159245.
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    245. Szefler SJ, Martin RJ. Lessons learned from variation in response to therapy in clinical trials. J Allergy Clin Immunol. 2010 Feb; 125(2):285-92; quiz 293-4. PMID: 20074785.
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    246. Szefler SJ. Advances in pediatric asthma in 2009: gaining control of childhood asthma. J Allergy Clin Immunol. 2010 Jan; 125(1):69-78. PMID: 20109738.
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    247. Wechsler ME, Kunselman SJ, Chinchilli VM, Bleecker E, Boushey HA, Calhoun WJ, Ameredes BT, Castro M, Craig TJ, Denlinger L, Fahy JV, Jarjour N, Kazani S, Kim S, Kraft M, Lazarus SC, Lemanske RF, Markezich A, Martin RJ, Permaul P, Peters SP, Ramsdell J, Sorkness CA, Sutherland ER, Szefler SJ, Walter MJ, Wasserman SI, Israel E. Effect of beta2-adrenergic receptor polymorphism on response to longacting beta2 agonist in asthma (LARGE trial): a genotype-stratified, randomised, placebo-controlled, crossover trial. Lancet. 2009 Nov 21; 374(9703):1754-64. PMID: 19932356.
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    248. Haselkorn T, Zeiger RS, Chipps BE, Mink DR, Szefler SJ, Simons FE, Massanari M, Fish JE. Recent asthma exacerbations predict future exacerbations in children with severe or difficult-to-treat asthma. J Allergy Clin Immunol. 2009 Nov; 124(5):921-7. PMID: 19895984.
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    249. Haselkorn T, Fish JE, Zeiger RS, Szefler SJ, Miller DP, Chipps BE, Simons FE, Weiss ST, Wenzel SE, Borish L, Bleecker ER. Consistently very poorly controlled asthma, as defined by the impairment domain of the Expert Panel Report 3 guidelines, increases risk for future severe asthma exacerbations in The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) study. J Allergy Clin Immunol. 2009 Nov; 124(5):895-902.e1-4. PMID: 19811812.
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    250. Long AA, Fish JE, Rahmaoui A, Miller MK, Bradley MS, Taki HN, Demeo AN, Tilles SA, Szefler SJ. Baseline characteristics of patients enrolled in EXCELS: a cohort study. Ann Allergy Asthma Immunol. 2009 Sep; 103(3):212-9. PMID: 19788018.
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    251. Rogers AJ, Tantisira KG, Fuhlbrigge AL, Litonjua AA, Lasky-Su JA, Szefler SJ, Strunk RC, Zeiger RS, Weiss ST. Predictors of poor response during asthma therapy differ with definition of outcome. Pharmacogenomics. 2009 Aug; 10(8):1231-42. PMID: 19663668.
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    252. Gruchalla RS, Sampson HA, Matsui E, David G, Gergen PJ, Calatroni A, Brown M, Liu AH, Bloomberg GR, Chmiel JF, Kumar R, Lamm C, Smartt E, Sorkness CA, Steinbach SF, Stone KD, Szefler SJ, Busse WW. Asthma morbidity among inner-city adolescents receiving guidelines-based therapy: role of predictors in the setting of high adherence. J Allergy Clin Immunol. 2009 Aug; 124(2):213-21, 221.e1. PMID: 19615730.
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    253. Kruzick T, Covar RA, Gleason M, Cicutto L, White M, Shocks D, Szefler SJ. Does access to care equal asthma control in school-age children? J Allergy Clin Immunol. 2009 Aug; 124(2):381-3. PMID: 19596141.
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    254. Szefler SJ. Managing asthma and allergies in schools: an opportunity to coordinate health care. J Allergy Clin Immunol. 2009 Aug; 124(2):201-4. PMID: 19596144.
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    255. Reddel HK, Taylor DR, Bateman ED, Boulet LP, Boushey HA, Busse WW, Casale TB, Chanez P, Enright PL, Gibson PG, de Jongste JC, Kerstjens HA, Lazarus SC, Levy ML, O'Byrne PM, Partridge MR, Pavord ID, Sears MR, Sterk PJ, Stoloff SW, Sullivan SD, Szefler SJ, Thomas MD, Wenzel SE. An official American Thoracic Society/European Respiratory Society statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials and clinical practice. Am J Respir Crit Care Med. 2009 Jul 01; 180(1):59-99. PMID: 19535666.
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    256. Bacharier LB, Guilbert TW, Zeiger RS, Strunk RC, Morgan WJ, Lemanske RF, Moss M, Szefler SJ, Krawiec M, Boehmer S, Mauger D, Taussig LM, Martinez FD. Patient characteristics associated with improved outcomes with use of an inhaled corticosteroid in preschool children at risk for asthma. J Allergy Clin Immunol. 2009 May; 123(5):1077-82, 1082.e1-5. PMID: 19230959.
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    257. Strunk RC, Sternberg AL, Szefler SJ, Zeiger RS, Bender B, Tonascia J. Long-term budesonide or nedocromil treatment, once discontinued, does not alter the course of mild to moderate asthma in children and adolescents. J Pediatr. 2009 May; 154(5):682-7. PMID: 19167726.
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    258. Knuffman JE, Sorkness CA, Lemanske RF, Mauger DT, Boehmer SJ, Martinez FD, Bacharier LB, Strunk RC, Szefler SJ, Zeiger RS, Taussig LM. Phenotypic predictors of long-term response to inhaled corticosteroid and leukotriene modifier therapies in pediatric asthma. J Allergy Clin Immunol. 2009 Feb; 123(2):411-6. PMID: 19121860.
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    259. Szefler SJ. Advances in pediatric asthma in 2008: where do we go now? J Allergy Clin Immunol. 2009 Jan; 123(1):28-34. PMID: 19130924.
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    260. Larsen GL, Morgan W, Heldt GP, Mauger DT, Boehmer SJ, Chinchilli VM, Lemanske RF, Martinez F, Strunk RC, Szefler SJ, Zeiger RS, Taussig LM, Bacharier LB, Guilbert TW, Radford S, Sorkness CA. Impulse oscillometry versus spirometry in a long-term study of controller therapy for pediatric asthma. J Allergy Clin Immunol. 2009 Apr; 123(4):861-7.e1. PMID: 19070356.
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    261. Bacharier LB, Phillips BR, Zeiger RS, Szefler SJ, Martinez FD, Lemanske RF, Sorkness CA, Bloomberg GR, Morgan WJ, Paul IM, Guilbert T, Krawiec M, Covar R, Larsen G, Mellon M, Moss MH, Chinchilli VM, Taussig LM, Strunk RC. Episodic use of an inhaled corticosteroid or leukotriene receptor antagonist in preschool children with moderate-to-severe intermittent wheezing. J Allergy Clin Immunol. 2008 Dec; 122(6):1127-1135.e8. PMID: 18973936.
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    262. Strunk RC, Bacharier LB, Phillips BR, Szefler SJ, Zeiger RS, Chinchilli VM, Martinez FD, Lemanske RF, Taussig LM, Mauger DT, Morgan WJ, Sorkness CA, Paul IM, Guilbert T, Krawiec M, Covar R, Larsen G. Azithromycin or montelukast as inhaled corticosteroid-sparing agents in moderate-to-severe childhood asthma study. J Allergy Clin Immunol. 2008 Dec; 122(6):1138-1144.e4. PMID: 18951618.
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    263. Sharma S, Litonjua AA, Tantisira KG, Fuhlbrigge AL, Szefler SJ, Strunk RC, Zeiger RS, Murphy AJ, Weiss ST. Clinical predictors and outcomes of consistent bronchodilator response in the childhood asthma management program. J Allergy Clin Immunol. 2008 Nov; 122(5):921-928.e4. PMID: 18848350.
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    264. Szefler SJ. Asthma exacerbations: putting a lid on the volcano. J Allergy Clin Immunol. 2008 Oct; 122(4):697-699. PMID: 19014760.
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    265. Covar RA, Szefler SJ, Zeiger RS, Sorkness CA, Moss M, Mauger DT, Boehmer SJ, Strunk RC, Martinez FD, Taussig LM. Factors associated with asthma exacerbations during a long-term clinical trial of controller medications in children. J Allergy Clin Immunol. 2008 Oct; 122(4):741-747.e4. PMID: 19014765.
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    266. Szefler SJ, Mitchell H, Sorkness CA, Gergen PJ, O'Connor GT, Morgan WJ, Kattan M, Pongracic JA, Teach SJ, Bloomberg GR, Eggleston PA, Gruchalla RS, Kercsmar CM, Liu AH, Wildfire JJ, Curry MD, Busse WW. Management of asthma based on exhaled nitric oxide in addition to guideline-based treatment for inner-city adolescents and young adults: a randomised controlled trial. Lancet. 2008 Sep 20; 372(9643):1065-72. PMID: 18805335.
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    267. Walter MJ, Castro M, Kunselman SJ, Chinchilli VM, Reno M, Ramkumar TP, Avila PC, Boushey HA, Ameredes BT, Bleecker ER, Calhoun WJ, Cherniack RM, Craig TJ, Denlinger LC, Israel E, Fahy JV, Jarjour NN, Kraft M, Lazarus SC, Lemanske RF, Martin RJ, Peters SP, Ramsdell JW, Sorkness CA, Sutherland ER, Szefler SJ, Wasserman SI, Wechsler ME. Predicting worsening asthma control following the common cold. Eur Respir J. 2008 Dec; 32(6):1548-54. PMID: 18768579.
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    268. Taylor DR, Bateman ED, Boulet LP, Boushey HA, Busse WW, Casale TB, Chanez P, Enright PL, Gibson PG, de Jongste JC, Kerstjens HA, Lazarus SC, Levy ML, O'Byrne PM, Partridge MR, Pavord ID, Sears MR, Sterk PJ, Stoloff SW, Szefler SJ, Sullivan SD, Thomas MD, Wenzel SE, Reddel HK. A new perspective on concepts of asthma severity and control. Eur Respir J. 2008 Sep; 32(3):545-54. PMID: 18757695.
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    269. Neville KA, Szefler SJ, Abdel-Rahman SM, Lahu G, Zech K, Herzog R, Bethke TD, Gleason MC, Kearns GL. Single-dose pharmacokinetics of roflumilast in children and adolescents. J Clin Pharmacol. 2008 Aug; 48(8):978-85. PMID: 18508947.
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    270. Wamboldt FS, Balkissoon RC, Rankin AE, Szefler SJ, Hammond SK, Glasgow RE, Dickinson WP. Correlates of household smoking bans in low-income families of children with and without asthma. Fam Process. 2008 Mar; 47(1):81-94. PMID: 18411831.
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    271. Szefler SJ. Asthma progression: can we and should we measure it? J Allergy Clin Immunol. 2008 Mar; 121(3):598-600. PMID: 18234308.
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    272. Szefler SJ. Advances in pediatric asthma in 2007. J Allergy Clin Immunol. 2008 Mar; 121(3):614-9. PMID: 18234318.
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    273. Szefler SJ. Individualizing asthma therapy: application of biomarkers. J Asthma. 2008; 45 Suppl 1:29-31. PMID: 19093283.
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    274. Szefler SJ, Baker JW, Uryniak T, Goldman M, Silkoff PE. Comparative study of budesonide inhalation suspension and montelukast in young children with mild persistent asthma. J Allergy Clin Immunol. 2007 Nov; 120(5):1043-50. PMID: 17983871.
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    275. Bisgaard H, Szefler S. Prevalence of asthma-like symptoms in young children. Pediatr Pulmonol. 2007 Aug; 42(8):723-8. PMID: 17598172.
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    276. Spahn JD, Szefler SJ. Steroid therapy for asthma in children. Curr Opin Pediatr. 2007 Jun; 19(3):300-5. PMID: 17505190.
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    277. Chipps BE, Szefler SJ, Simons FE, Haselkorn T, Mink DR, Deniz Y, Lee JH. Demographic and clinical characteristics of children and adolescents with severe or difficult-to-treat asthma. J Allergy Clin Immunol. 2007 May; 119(5):1156-63. PMID: 17397912.
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    278. Szefler SJ. Advances in pediatric asthma 2006. J Allergy Clin Immunol. 2007 Mar; 119(3):558-62. PMID: 17270259.
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    279. Lazarus SC, Chinchilli VM, Rollings NJ, Boushey HA, Cherniack R, Craig TJ, Deykin A, DiMango E, Fish JE, Ford JG, Israel E, Kiley J, Kraft M, Lemanske RF, Leone FT, Martin RJ, Pesola GR, Peters SP, Sorkness CA, Szefler SJ, Wechsler ME, Fahy JV. Smoking affects response to inhaled corticosteroids or leukotriene receptor antagonists in asthma. Am J Respir Crit Care Med. 2007 Apr 15; 175(8):783-90. PMID: 17204725.
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    313. O'Connor SL, Bender BG, Gavin-Devitt LA, Wamboldt MZ, Milgrom H, Szefler S, Rand C, Wamboldt FS. Measuring adherence with the Doser CT in children with asthma. J Asthma. 2004 Sep; 41(6):663-70. PMID: 15584316.
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    337. Spahn JD, Szefler SJ. Inhaled steroids: are they all created equal? Semin Respir Crit Care Med. 2002 Aug; 23(4):377-86. PMID: 16088631.
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    356. Vanden Burgt JA, Busse WW, Martin RJ, Szefler SJ, Donnell D. Efficacy and safety overview of a new inhaled corticosteroid, QVAR (hydrofluoroalkane-beclomethasone extrafine inhalation aerosol), in asthma. J Allergy Clin Immunol. 2000 Dec; 106(6):1209-26. PMID: 11112914.
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    369. Hauk PJ, Wenzel SE, Trumble AE, Szefler SJ, Leung DY. Increased T-cell receptor vbeta8+ T cells in bronchoalveolar lavage fluid of subjects with poorly controlled asthma: a potential role for microbial superantigens. J Allergy Clin Immunol. 1999 Jul; 104(1):37-45. PMID: 10400837.
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    370. Wamboldt FS, Bender BG, O'Connor SL, Gavin LA, Wamboldt MZ, Milgrom H, Szefler SJ, Ikl? D, Rand C. Reliability of the model MC-311 MDI chronolog. J Allergy Clin Immunol. 1999 Jul; 104(1):53-7. PMID: 10400839.
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    371. Fost DA, Leung DY, Martin RJ, Brown EE, Szefler SJ, Spahn JD. Inhibition of methylprednisolone elimination in the presence of clarithromycin therapy. J Allergy Clin Immunol. 1999 Jun; 103(6):1031-5. PMID: 10359882.
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    372. Hamid QA, Wenzel SE, Hauk PJ, Tsicopoulos A, Wallaert B, Lafitte JJ, Chrousos GP, Szefler SJ, Leung DY. Increased glucocorticoid receptor beta in airway cells of glucocorticoid-insensitive asthma. Am J Respir Crit Care Med. 1999 May; 159(5 Pt 1):1600-4. PMID: 10228133.
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    373. Szefler SJ, Boushey HA, Pearlman DS, Togias A, Liddle R, Furlong A, Shah T, Knobil K. Time to onset of effect of fluticasone propionate in patients with asthma. J Allergy Clin Immunol. 1999 May; 103(5 Pt 1):780-8. PMID: 10329810.
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    374. Spahn JD, Leung DY, Chan MT, Szefler SJ, Gelfand EW. Mechanisms of glucocorticoid reduction in asthmatic subjects treated with intravenous immunoglobulin. J Allergy Clin Immunol. 1999 Mar; 103(3 Pt 1):421-6. PMID: 10069875.
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    375. Szefler SJ. Corticosteroid treatment of asthma: now at the crossroads. Reply to Drs Seale and Donnelly. Respir Med. 1999 Feb; 93(2):142-4. PMID: 10507939.
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    376. Leung DY, Spahn JD, Szefler SJ. Immunologic basis and management of steroid-resistant asthma. Allergy Asthma Proc. 1999 Jan-Feb; 20(1):9-14. PMID: 10076704.
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    377. Chu HW, Halliday JL, Martin RJ, Leung DY, Szefler SJ, Wenzel SE. Collagen deposition in large airways may not differentiate severe asthma from milder forms of the disease. Am J Respir Crit Care Med. 1998 Dec; 158(6):1936-44. PMID: 9847289.
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    378. Szefler SJ. Early intervention for childhood asthma: inhaled glucocorticoids as the "preferred" medication. J Allergy Clin Immunol. 1998 Nov; 102(5):719-21. PMID: 9819286.
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    379. Szefler SJ, Nelson HS. Alternative agents for anti-inflammatory treatment of asthma. J Allergy Clin Immunol. 1998 Oct; 102(4 Pt 2):S23-35. PMID: 9798721.
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    380. Szefler SJ. Leukotriene modifiers: what is their position in asthma therapy? J Allergy Clin Immunol. 1998 Aug; 102(2):170-2. PMID: 9723656.
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    381. Nimmagadda SR, Spahn JD, Nelson HS, Jenkins J, Szefler SJ, Leung DY. Fluticasone propionate results in improved glucocorticoid receptor binding affinity and reduced oral glucocorticoid requirements in severe asthma. Ann Allergy Asthma Immunol. 1998 Jul; 81(1):35-40. PMID: 9690571.
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    382. Pedersen S, Szefler S. Pharmacological interventions. Childhood asthma. Eur Respir J Suppl. 1998 Jul; 27:40s-45s. PMID: 9699783.
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    383. Shapiro G, Bronsky EA, LaForce CF, Mendelson L, Pearlman D, Schwartz RH, Szefler SJ. Dose-related efficacy of budesonide administered via a dry powder inhaler in the treatment of children with moderate to severe persistent asthma. J Pediatr. 1998 Jun; 132(6):976-82. PMID: 9627589.
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    384. Leung DY, de Castro M, Szefler SJ, Chrousos GP. Mechanisms of glucocorticoid-resistant asthma. Ann N Y Acad Sci. 1998 May 01; 840:735-46. PMID: 9629300.
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    385. Chan MT, Leung DY, Szefler SJ, Spahn JD. Difficult-to-control asthma: clinical characteristics of steroid-insensitive asthma. J Allergy Clin Immunol. 1998 May; 101(5):594-601. PMID: 9600494.
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    386. Leung DY, Szefler SJ. New insights into steroid resistant asthma. Pediatr Allergy Immunol. 1998 Feb; 9(1):3-12. PMID: 9560836.
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    387. Kamada AK, Szefler SJ. The safety of inhaled corticosteroid therapy in children. Curr Opin Pediatr. 1997 Dec; 9(6):585-9. PMID: 9425592.
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    388. Leung DY, Hamid Q, Vottero A, Szefler SJ, Surs W, Minshall E, Chrousos GP, Klemm DJ. Association of glucocorticoid insensitivity with increased expression of glucocorticoid receptor beta. J Exp Med. 1997 Nov 03; 186(9):1567-74. PMID: 9348314.
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    389. Lanz MJ, Leung DY, McCormick DR, Harbeck R, Szefler SJ, White CW. Comparison of exhaled nitric oxide, serum eosinophilic cationic protein, and soluble interleukin-2 receptor in exacerbations of pediatric asthma. Pediatr Pulmonol. 1997 Nov; 24(5):305-11. PMID: 9407562.
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    390. Fish JE, Peters SP, Chambers CV, McGeady SJ, Epstein KR, Boushey HA, Cherniack RM, Chinchilli VM, Drazen JM, Fahy JV, Hurd SS, Israel E, Lazarus SC, Lemanske RF, Martin RJ, Mauger EA, Sorkness C, Szefler SJ. An evaluation of colchicine as an alternative to inhaled corticosteriods in moderate asthma. National Heart, Lung, and Blood Institute's Asthma Clinical Research Network. Am J Respir Crit Care Med. 1997 Oct; 156(4 Pt 1):1165-71. PMID: 9351617.
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    391. Wenzel SE, Szefler SJ, Leung DY, Sloan SI, Rex MD, Martin RJ. Bronchoscopic evaluation of severe asthma. Persistent inflammation associated with high dose glucocorticoids. Am J Respir Crit Care Med. 1997 Sep; 156(3 Pt 1):737-43. PMID: 9309987.
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    392. Leung DY, Szefler SJ. Diagnosis and management of steroid-resistant asthma. Clin Chest Med. 1997 Sep; 18(3):611-25. PMID: 9329880.
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    393. Szefler SJ, Leung DY. Glucocorticoid-resistant asthma: pathogenesis and clinical implications for management. Eur Respir J. 1997 Jul; 10(7):1640-7. PMID: 9230260.
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    394. Kamada AK, Szefler SJ. How should inhaled glucocorticoids be compared? J Allergy Clin Immunol. 1997 Jun; 99(6 Pt 1):735-7. PMID: 9215238.
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    395. Kamada AK, Wiener MB, LaVallee NM, Scott MB, Selner JC, Szefler SJ. A pharmacokinetic comparison of two oral liquid glucocorticoid formulations. Pharmacotherapy. 1997 Mar-Apr; 17(2):353-6. PMID: 9085328.
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    396. Nimmagadda SR, Szefler SJ, Spahn JD, Surs W, Leung DY. Allergen exposure decreases glucocorticoid receptor binding affinity and steroid responsiveness in atopic asthmatics. Am J Respir Crit Care Med. 1997 Jan; 155(1):87-93. PMID: 9001294.
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    397. Spahn JD, Leung DY, Szefler SJ. New insights into the pathogenesis and management of steroid-resistant asthma. J Asthma. 1997; 34(3):177-94. PMID: 9168845.
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    398. Spahn JD, Szefler SJ. The etiology and control of bronchial hyperresponsiveness in children. Curr Opin Pediatr. 1996 Dec; 8(6):591-6. PMID: 9018442.
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    399. Spahn JD, Landwehr LP, Nimmagadda S, Surs W, Leung DY, Szefler SJ. Effects of glucocorticoids on lymphocyte activation in patients with steroid-sensitive and steroid-resistant asthma. J Allergy Clin Immunol. 1996 Dec; 98(6 Pt 1):1073-9. PMID: 8977508.
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    400. Nimmagadda SR, Spahn JD, Leung DY, Szefler SJ. Steroid-resistant asthma: evaluation and management. Ann Allergy Asthma Immunol. 1996 Nov; 77(5):345-55; quiz 355-6. PMID: 8933772.
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    401. Drazen JM, Israel E, Boushey HA, Chinchilli VM, Fahy JV, Fish JE, Lazarus SC, Lemanske RF, Martin RJ, Peters SP, Sorkness C, Szefler SJ. Comparison of regularly scheduled with as-needed use of albuterol in mild asthma. Asthma Clinical Research Network. N Engl J Med. 1996 Sep 19; 335(12):841-7. PMID: 8778601.
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    402. Spahn JD, Szefler SJ, Surs W, Doherty DE, Nimmagadda SR, Leung DY. A novel action of IL-13: induction of diminished monocyte glucocorticoid receptor-binding affinity. J Immunol. 1996 Sep 15; 157(6):2654-9. PMID: 8805670.
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    403. Leung DY, Spahn JD, Nimmagadda SR, Szefler SJ. Induction of corticosteroid resistance in vitro. Am J Respir Crit Care Med. 1996 Aug; 154(2 Pt 2):S34-7; discussion S37-8. PMID: 8756785.
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    404. Kamada AK, Szefler SJ. The role of theophylline in the treatment of asthma. Ann Allergy Asthma Immunol. 1996 Jul; 77(1):1-3. PMID: 8705629.
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    405. Kamada AK, Szefler SJ, Martin RJ, Boushey HA, Chinchilli VM, Drazen JM, Fish JE, Israel E, Lazarus SC, Lemanske RF. Issues in the use of inhaled glucocorticoids. The Asthma Clinical Research Network. Am J Respir Crit Care Med. 1996 Jun; 153(6 Pt 1):1739-48. PMID: 8665030.
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    406. Stempel DA, Szefler SJ. Going beyond the National Asthma Education Program guidelines for the diagnosis and management of asthma: critical need for outcomes assessment. Ann Allergy Asthma Immunol. 1995 Dec; 75(6 Pt 1):457-60. PMID: 8603272.
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    407. Clayton MH, Leung DY, Surs W, Szefler SJ. Altered glucocorticoid receptor binding in atopic dermatitis. J Allergy Clin Immunol. 1995 Sep; 96(3):421-3. PMID: 7560645.
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    408. Kamada AK, Szefler SJ. Glucocorticoids and growth in asthmatic children. Pediatr Allergy Immunol. 1995 Aug; 6(3):145-54. PMID: 8750310.
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    409. Szefler SJ, Bender BG, Jusko WJ, Lanier BQ, Lemanske RF, Skoner DP, Stempel DA. Evolving role of theophylline for treatment of chronic childhood asthma. J Pediatr. 1995 Aug; 127(2):176-85. PMID: 7636640.
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    410. Pincus DJ, Szefler SJ, Ackerson LM, Martin RJ. Chronotherapy of asthma with inhaled steroids: the effect of dosage timing on drug efficacy. J Allergy Clin Immunol. 1995 Jun; 95(6):1172-8. PMID: 7797785.
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    411. Spahn JD, Leung DY, Surs W, Harbeck RJ, Nimmagadda S, Szefler SJ. Reduced glucocorticoid binding affinity in asthma is related to ongoing allergic inflammation. Am J Respir Crit Care Med. 1995 Jun; 151(6):1709-14. PMID: 7767511.
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    412. Leflein J, Brown E, Hill M, Kelly HW, Loffert DT, Nelson HS, Szefler SJ. Delivery of glucocorticoids by jet nebulization: aerosol characteristics and output. J Allergy Clin Immunol. 1995 May; 95(5 Pt 1):944-9. PMID: 7751514.
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    413. Leung DY, Martin RJ, Szefler SJ, Sher ER, Ying S, Kay AB, Hamid Q. Dysregulation of interleukin 4, interleukin 5, and interferon gamma gene expression in steroid-resistant asthma. J Exp Med. 1995 Jan 01; 181(1):33-40. PMID: 7807013.
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    414. Kamada AK, Spahn JD, Surs W, Brown E, Leung DY, Szefler SJ. Coexistence of glucocorticoid receptor and pharmacokinetic abnormalities: factors that contribute to a poor response to treatment with glucocorticoids in children with asthma. J Pediatr. 1994 Jun; 124(6):984-6. PMID: 8201491.
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    415. Sher ER, Leung DY, Surs W, Kam JC, Zieg G, Kamada AK, Szefler SJ. Steroid-resistant asthma. Cellular mechanisms contributing to inadequate response to glucocorticoid therapy. J Clin Invest. 1994 Jan; 93(1):33-9. PMID: 8282803.
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    416. Kam JC, Szefler SJ, Surs W, Sher ER, Leung DY. Combination IL-2 and IL-4 reduces glucocorticoid receptor-binding affinity and T cell response to glucocorticoids. J Immunol. 1993 Oct 01; 151(7):3460-6. PMID: 8376786.
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    417. Kamada AK, Hill MR, Ikl? DN, Brenner AM, Szefler SJ. Efficacy and safety of low-dose troleandomycin therapy in children with severe, steroid-requiring asthma. J Allergy Clin Immunol. 1993 Apr; 91(4):873-82. PMID: 8473676.
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    418. Stempel DA, Szefler SJ. Management of chronic asthma. Pediatr Clin North Am. 1992 Dec; 39(6):1293-310. PMID: 1331944.
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    419. Hill M, Szefler SJ, Larsen GL. Asthma pathogenesis and the implications for therapy in children. Pediatr Clin North Am. 1992 Dec; 39(6):1205-24. PMID: 1437316.
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    420. Kamada AK, Leung DY, Szefler SJ. Steroid resistance in asthma: our current understanding. Pediatr Pulmonol. 1992 Nov; 14(3):180-6. PMID: 1480444.
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    421. Kamada AK, Leung DY, Gleason MC, Hill MR, Szefler SJ. High-dose systemic glucocorticoid therapy in the treatment of severe asthma: a case of resistance and patterns of response. J Allergy Clin Immunol. 1992 Oct; 90(4 Pt 1):685-7. PMID: 1401649.
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    422. Kamada AK, Szefler SJ. Inhaled therapy in infants: why not nebulize glucocorticoids? Pediatr Pulmonol. 1992 Aug; 13(4):198-9. PMID: 1523026.
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    423. Szefler SJ. Anti-inflammatory drugs in the treatment of allergic disease. Med Clin North Am. 1992 Jul; 76(4):953-75. PMID: 1351972.
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    424. Dove AM, Szefler SJ, Hill MR, Jusko WJ, Larsen GL, Accurso FJ. Altered prednisolone pharmacokinetics in patients with cystic fibrosis. J Pediatr. 1992 May; 120(5):789-94. PMID: 1578318.
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    425. Altman LC, Findlay SR, Lopez M, Lukacsko P, Morris RJ, Pinnas JL, Ratner PH, Szefler SJ, Welch MJ. Adrenal function in adult asthmatics during long-term daily treatment with 800, 1,200, and 1,600 micrograms triamcinolone acetonide. Multicenter study. Chest. 1992 May; 101(5):1250-6. PMID: 1582280.
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    426. Alvarez J, Surs W, Leung DY, Ikl? D, Gelfand EW, Szefler SJ. Steroid-resistant asthma: immunologic and pharmacologic features. J Allergy Clin Immunol. 1992 Mar; 89(3):714-21. PMID: 1545093.
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    427. Kamada AK, Parks DP, Szefler SJ. Inhaled glucocorticoid therapy in children: how much is safe? Pediatr Pulmonol. 1992 Feb; 12(2):71-2. PMID: 1570191.
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    428. Hendeles L, Weinberger M, Szefler S, Ellis E. Safety and efficacy of theophylline in children with asthma. J Pediatr. 1992 Feb; 120(2 Pt 1):177-83. PMID: 1735811.
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    429. Zaragoza RH, Szefler SJ, Bratton DL. Brief report: therapeutic manipulations in severe nocturnal asthma. A nonconventional approach in a severe high-risk asthmatic. J Asthma. 1992; 29(4):281-7. PMID: 1386072.
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    430. Szefler SJ, Kamada AK, Hughes D, Brenner AM, Gelfand EW. Alternative treatments for asthma: assessing the need. J Asthma. 1992; 29(2):91-7. PMID: 1639739.
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    431. Glynn-Barnhart AM, Erzurum SC, Leff JA, Martin RJ, Cochran JE, Cott GR, Szefler SJ. Pharmacokinetics of low-dose methotrexate in adult asthmatics. Pharmacotherapy. 1992; 12(5):383-90. PMID: 1437699.
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    432. Alvarez J, Szefler SJ. Alternative therapy in severe asthma. J Asthma. 1992; 29(1):3-11. PMID: 1544882.
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    433. Kamada AK, Hill MR, Brenner AM, Szefler SJ. Effect of low-dose troleandomycin on theophylline clearance: implications for therapeutic drug monitoring. Pharmacotherapy. 1992; 12(2):98-102. PMID: 1570234.
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    434. Corrigan CJ, Brown PH, Barnes NC, Szefler SJ, Tsai JJ, Frew AJ, Kay AB. Glucocorticoid resistance in chronic asthma. Glucocorticoid pharmacokinetics, glucocorticoid receptor characteristics, and inhibition of peripheral blood T cell proliferation by glucocorticoids in vitro. Am Rev Respir Dis. 1991 Nov; 144(5):1016-25. PMID: 1952426.
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    435. Greos LS, Vichyanond P, Bloedow DC, Irvin CG, Larsen GL, Szefler SJ, Hill MR. Methylprednisolone achieves greater concentrations in the lung than prednisolone. A pharmacokinetic analysis. Am Rev Respir Dis. 1991 Sep; 144(3 Pt 1):586-92. PMID: 1892299.
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    436. Glynn-Barnhart AM, Erzurum SC, Leff JA, Martin RJ, Cochran JE, Cott GR, Szefler SJ. Effect of low-dose methotrexate on the disposition of glucocorticoids and theophylline. J Allergy Clin Immunol. 1991 Aug; 88(2):180-6. PMID: 1880318.
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    437. Szefler SJ. Glucocorticoid therapy for asthma: clinical pharmacology. J Allergy Clin Immunol. 1991 Aug; 88(2):147-65. PMID: 1880315.
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    438. Nelson HS, Szefler SJ, Martin RJ. Regular inhaled beta-adrenergic agonists in the treatment of bronchial asthma: beneficial or detrimental? Am Rev Respir Dis. 1991 Aug; 144(2):249-50. PMID: 1677552.
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    439. Erzurum SC, Leff JA, Cochran JE, Ackerson LM, Szefler SJ, Martin RJ, Cott GR. Lack of benefit of methotrexate in severe, steroid-dependent asthma. A double-blind, placebo-controlled study. Ann Intern Med. 1991 Mar 01; 114(5):353-60. PMID: 1992876.
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    440. Martin RJ, Cicutto LC, Smith HR, Ballard RD, Szefler SJ. Airways inflammation in nocturnal asthma. Am Rev Respir Dis. 1991 Feb; 143(2):351-7. PMID: 1990952.
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    441. Szefler SJ, Ando R, Cicutto LC, Surs W, Hill MR, Martin RJ. Plasma histamine, epinephrine, cortisol, and leukocyte beta-adrenergic receptors in nocturnal asthma. Clin Pharmacol Ther. 1991 Jan; 49(1):59-68. PMID: 1846332.
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    442. Bender BG, Lerner JA, Ikle D, Comer C, Szefler S. Psychological change associated with theophylline treatment of asthmatic children: a 6-month study. Pediatr Pulmonol. 1991; 11(3):233-42. PMID: 1758745.
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    443. Hill MR, Szefler SJ, Ball BD, Bartoszek M, Brenner AM. Monitoring glucocorticoid therapy: a pharmacokinetic approach. Clin Pharmacol Ther. 1990 Oct; 48(4):390-8. PMID: 2225699.
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    444. Vichyanond P, Sladek WA, Sur S, Hill MR, Szefler SJ, Nelson HS. Efficacy of atropine methylnitrate alone and in combination with albuterol in children with asthma. Chest. 1990 Sep; 98(3):637-42. PMID: 2203617.
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    445. Ball BD, Hill MR, Brenner M, Sanks R, Szefler SJ. Effect of low-dose troleandomycin on glucocorticoid pharmacokinetics and airway hyperresponsiveness in severely asthmatic children. Ann Allergy. 1990 Jul; 65(1):37-45. PMID: 2195921.
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    446. Szefler SJ. Measuring the response to glucocorticoids. J Allergy Clin Immunol. 1990 Jun; 85(6):985-7. PMID: 2355157.
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    447. Vichyanond P, Irvin CG, Larsen GL, Szefler SJ, Hill MR. Penetration of corticosteroids into the lung: evidence for a difference between methylprednisolone and prednisolone. J Allergy Clin Immunol. 1989 Dec; 84(6 Pt 1):867-73. PMID: 2600321.
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    448. Kossoy AF, Hill M, Lin FL, Szefler SJ. Are theophylline "levels" a reliable indicator of compliance? J Allergy Clin Immunol. 1989 Jul; 84(1):60-5. PMID: 2754145.
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    449. Szefler SJ, Norton CE, Ball B, Gross JM, Aida Y, Pabst MJ. IFN-gamma and LPS overcome glucocorticoid inhibition of priming for superoxide release in human monocytes. Evidence that secretion of IL-1 and tumor necrosis factor-alpha is not essential for monocyte priming. J Immunol. 1989 Jun 01; 142(11):3985-92. PMID: 2541203.
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    450. Glynn-Barnhart A, Hill M, Szefler SJ. Sustained release theophylline preparations. Practical recommendations for prescribing and therapeutic drug monitoring. Drugs. 1988 Jun; 35(6):711-26. PMID: 3048977.
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    451. Hill M, Haltom JR, Szefler SJ. The consistency of theophylline absorption from a sustained-release formulation in asthmatic children. Pharmacotherapy. 1988; 8(5):277-83. PMID: 3255299.
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    452. Rogers RJ, Wiener MB, Hill MR, Szefler SJ. Theophylline absorption from two sustained-release products. Implications for therapeutic drug monitoring. Am Rev Respir Dis. 1987 Nov; 136(5):1168-73. PMID: 3674579.
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    453. Bartoszek M, Brenner AM, Szefler SJ. Prednisolone and methylprednisolone kinetics in children receiving anticonvulsant therapy. Clin Pharmacol Ther. 1987 Oct; 42(4):424-32. PMID: 3665340.
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    454. Weinberger M, Lindgren S, Bender B, Lerner JA, Szefler S. Effects of theophylline on learning and behavior: reason for concern or concern without reason? J Pediatr. 1987 Sep; 111(3):471-4. PMID: 3305851.
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    455. Szefler SJ, Edwards CK, Haslett C, Zahniser NR, Miller JA, Henson PM. Effects of cell isolation procedures and radioligand selection on the characterization of human leukocyte beta-adrenergic receptors. Biochem Pharmacol. 1987 May 15; 36(10):1589-97. PMID: 3036150.
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    456. Ebling WF, Rich SA, Szefler SJ, Jusko WJ. Troleandomycin effects on methylprednisolone and methylprednisone interconversion and disposition in the rabbit. Eur J Drug Metab Pharmacokinet. 1987 Jan-Mar; 12(1):50-7. PMID: 3497038.
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    457. Bartoszek M, Szefler SJ. Corticosteroid therapy in adolescent patients. J Adolesc Health Care. 1987 Jan; 8(1):84-91. PMID: 3546229.
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    458. Szefler SJ. Erratic absorption of theophylline from slow-release products in children. J Allergy Clin Immunol. 1986 Oct; 78(4 Pt 2):710-5. PMID: 3534052.
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    459. Ebling WF, Milsap RL, Szefler SJ, Jusko WJ. 6 alpha-Methylprednisolone and 6 alpha-methylprednisone plasma protein binding in humans and rabbits. J Pharm Sci. 1986 Aug; 75(8):760-3. PMID: 3772747.
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    460. Suez D, Szefler SJ. Excessive accumulation of mucus in children with asthma: a potential role for erythromycin? A case discussion. J Allergy Clin Immunol. 1986 Feb; 77(2):330-4. PMID: 3944384.
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    461. Vaughan LM, Weinberger MM, Milavetz G, Tillson S, Ellis E, Jenne J, Szefler SJ, Wiener MB, Conboy K, Shaughnessy T, et al. Multicentre evaluation of disposable visual measuring device to assay theophylline from capillary blood sample. Lancet. 1986 Jan 25; 1(8474):184-6. PMID: 2868208.
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    462. Szefler SJ, Ebling WF, Georgitis JW, Jusko WJ. Methylprednisolone versus prednisolone pharmacokinetics in relation to dose in adults. Eur J Clin Pharmacol. 1986; 30(3):323-9. PMID: 3732369.
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    463. Haltom JR, Szefler SJ. Theophylline absorption in young asthmatic children receiving sustained-release formulations. J Pediatr. 1985 Nov; 107(5):805-10. PMID: 4056986.
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    464. Szefler SJ. Theophylline and its fickle unpredictability of absorption. Ann Allergy. 1985 Oct; 55(4):580-3. PMID: 3901834.
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    465. Ebling WF, Szefler SJ, Jusko WJ. Methylprednisolone disposition in rabbits. Analysis, prodrug conversion, reversible metabolism, and comparison with man. Drug Metab Dispos. 1985 May-Jun; 13(3):296-304. PMID: 2861987.
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    466. Rogers RJ, Kalisker A, Wiener MB, Szefler SJ. Inconsistent absorption from a sustained-release theophylline preparation during continuous therapy in asthmatic children. J Pediatr. 1985 Mar; 106(3):496-501. PMID: 3973788.
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    467. Georgitis JW, Szefler SJ, Baswell B, Shen DD. Use of pharmacokinetic profile in evaluating patients with repeatedly low theophylline concentrations. Ann Allergy. 1984 Sep; 53(3):231-5. PMID: 6476482.
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    468. Szefler SJ, Rogers RJ, Strunk RC. Drug abuse and the asthmatic patient: a case report. J Allergy Clin Immunol. 1984 Aug; 74(2):201-4. PMID: 6747141.
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    469. Ebling WF, Szefler SJ, Jusko WJ. Analysis of cortisol, methylprednisolone, and methylprednisolone hemisuccinate. Absence of effects of troleandomycin on ester hydrolysis. J Chromatogr. 1984 Feb 10; 305(2):271-80. PMID: 6368578.
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    470. Szefler SJ. Inter- and intra-subject variability in theophylline pharmacokinetics. Br J Clin Pract Suppl. 1984; 35:10-6. PMID: 6433953.
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    471. Szefler SJ. Practical considerations in the safe and effective use of theophylline. Pediatr Clin North Am. 1983 Oct; 30(5):943-54. PMID: 6622082.
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    472. LaForce CF, Szefler SJ, Miller MF, Ebling W, Brenner M. Inhibition of methylprednisolone elimination in the presence of erythromycin therapy. J Allergy Clin Immunol. 1983 Jul; 72(1):34-9. PMID: 6602160.
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    473. Boekenoogen SJ, Szefler SJ, Jusko WJ. Prednisolone disposition and protein binding in oral contraceptive users. J Clin Endocrinol Metab. 1983 Apr; 56(4):702-9. PMID: 6833459.
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    474. Milsap RL, George DE, Szefler SJ, Murray KA, Lebenthal E, Jusko WJ. Effect of inflammatory bowel disease on absorption and disposition of prednisolone. Dig Dis Sci. 1983 Feb; 28(2):161-8. PMID: 6825536.
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    475. Szefler SJ. Drug excretion in human breast milk: potential effect on infant development. J Pediatr Gastroenterol Nutr. 1983; 2 Suppl 1:S120-6. PMID: 6644457.
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    476. Georgitis JW, Flesher KA, Szefler SJ. Bioavailability assessment of a liquid prednisone preparation. J Allergy Clin Immunol. 1982 Oct; 70(4):243-7. PMID: 7119300.
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    477. Szefler SJ, Pieroni DR, Gingell RL, Shen DD. Rapid elimination of quinidine in pediatric patients. Pediatrics. 1982 Sep; 70(3):370-5. PMID: 7110810.
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    478. Szefler SJ, Brenner M, Jusko WJ, Spector SL, Flesher KA, Ellis EF. Dose- and time-related effect of troleandomycin on methylprednisolone elimination. Clin Pharmacol Ther. 1982 Aug; 32(2):166-71. PMID: 6980076.
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    479. Szefler SJ, Ellis EF, Brenner M, Rose JQ, Spector SL, Yurchak AM, Andrews F, Jusko WJ. Steroid-specific and anticonvulsant interaction aspects of troleandomycin-steroid therapy. J Allergy Clin Immunol. 1982 May; 69(5):455-60. PMID: 6978898.
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    480. Zarowitz BJ, Wynn RJ, Buckwald S, Szefler SJ. High gentamicin trough concentrations in neonates of less than 28 weeks gestational age. Dev Pharmacol Ther. 1982; 5(1-2):68-75. PMID: 7151639.
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    481. Dederich RA, Szefler SJ, Green ER. Intrasubject variation in sustained-release theophylline absorption. J Allergy Clin Immunol. 1981 Jun; 67(6):465-71. PMID: 7346530.
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    482. Rocci ML, Szefler SJ, Acara M, Jusko WJ. Prednisolone metabolism and excretion in the isolated perfused rat kidney. Drug Metab Dispos. 1981 May-Jun; 9(3):177-82. PMID: 6113924.
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    483. Zarowitz BJ, Szefler SJ, Lasezkay GM. Effect of erythromycin base on theophylline kinetics. Clin Pharmacol Ther. 1981 May; 29(5):601-5. PMID: 7214790.
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    484. Lee TP, Szefler S, Ellis EF. Beta-adrenergic receptors of human polymorphonuclear leukocytes. Res Commun Chem Pathol Pharmacol. 1981 Mar; 31(3):453-62. PMID: 6265989.
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    485. Szefler SJ, Rose JQ, Ellis EF, Spector SL, Green AW, Jusko WJ. The effect of troleandomycin on methylprednisolone elimination. J Allergy Clin Immunol. 1980 Dec; 66(6):447-51. PMID: 6968763.
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    486. Szefler SJ, Wynn RJ, Clarke DF, Buckwald S, Shen D, Schentag JJ. Relationship of gentamicin serum concentrations to gestational age in preterm and term neonates. J Pediatr. 1980 Aug; 97(2):312-5. PMID: 7400909.
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    487. Szefler SJ, Acara M. Isoproterenol excretion and metabolism in the isolated perfused rat kidney. J Pharmacol Exp Ther. 1979 Aug; 210(2):295-300. PMID: 458636.
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    488. Szefler SJ, Koup JR, Giacoia GP. Paradoxical behavior of serum digoxin concentrations in an anuric neonate. J Pediatr. 1977 Sep; 91(3):487-9. PMID: 894426.
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    489. Jusko WJ, Szefler SJ, Goldfarb AL. Pharmacokinetic design of digoxin dosage regimens in relation to renal function. J Clin Pharmacol. 1974 Oct; 14(10):525-35. PMID: 4430731.
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    490. Szefler SJ, Jusko WJ. Decreased volume of distribution of digoxin in a patient with renal failure. Res Commun Chem Pathol Pharmacol. 1973 Nov; 6(3):1095-8. PMID: 4760884.
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