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Stanley J Szefler

TitleProfessor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-PEDS
Phone720/777-0985

    Collapse Research 
    Collapse research activities and funding
    N01HR016048     (SZEFLER, STANLEY J)Sep 30, 1991 - Apr 30, 2004
    NIH/NHLBI
    CLINICAL CENTER FOR CAMP
    Role: Principal Investigator

    U01HD037237     (SZEFLER, STANLEY J)Jan 1, 1999 - Dec 31, 2004
    NIH/NICHD
    PEDIATRIC PHARMACOLOGY RESEARCH UNIT
    Role: Principal Investigator

    U10HL064288     (SZEFLER, STANLEY JAMES)Sep 30, 1999 - May 31, 2010
    NIH/NHLBI
    Childhood Asthma Research and Education Network: Denver Site
    Role: Principal Investigator

    U01HL075416     (SZEFLER, STANLEY J)Sep 30, 2003 - Jun 30, 2012
    NIH/NHLBI
    CAMP Contiunation Study/Phase 3
    Role: Principal Investigator

    R21HL087811     (SZEFLER, STANLEY J)Sep 1, 2008 - Jun 30, 2011
    NIH/NHLBI
    Progression of Airway Obstruction in Childhood Asthma
    Role: Principal Investigator

    U10HL098075     (WECHSLER, MICHAEL E)Sep 30, 2009 - Jun 30, 2016
    NIH/NHLBI
    Clinical Centers for the NHLBI Asthma Network (AsthmaNet)
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Esquivel A, Busse WW, Calatroni A, Togias AG, Grindle KG, Bochkov YA, Gruchalla RS, Kattan M, Kercsmar CM, Khurana Hershey G, Kim H, Lebeau P, Liu AH, Szefler SJ, Teach SJ, West JB, Wildfire J, Pongracic JA, Gern JE. Effects of Omalizumab on Rhinovirus Infections, Illnesses and Exacerbations of Asthma. Am J Respir Crit Care Med. 2017 Jun 13. PMID: 28608756.
      View in: PubMed
    2. Chipps BE, Lanier B, Milgrom H, Deschildre A, Hedlin G, Szefler SJ, Kattan M, Kianifard F, Ortiz B, Haselkorn T, Iqbal A, Rosén K, Trzaskoma B, Busse WW. Omalizumab in children with uncontrolled allergic asthma: Review of clinical trial and real-world experience. J Allergy Clin Immunol. 2017 May; 139(5):1431-1444. PMID: 28477722.
      View in: PubMed
    3. Hamelmann E, Vogelberg C, Szefler SJ. Reply to 'Can a better patient phenotyping predict the efficacy of tiotropium in asthmatic adolescents?' Expert Opin Pharmacother. 2017 Jun; 18(8):837-838. PMID: 28399660.
      View in: PubMed
    4. Bacharier LB, Szefler SJ. Pediatric asthma - moving ahead faster than ever. Curr Opin Allergy Clin Immunol. 2017 Apr; 17(2):96-98. PMID: 28225363.
      View in: PubMed
    5. Kakumanu S, Antos N, Szefler SJ, Lemanske RF. Building school health partnerships to improve pediatric asthma care: the School-based Asthma Management Program. Curr Opin Allergy Clin Immunol. 2017 Apr; 17(2):160-166. PMID: 28177950.
      View in: PubMed
    6. Burbank AJ, Szefler SJ. Current and future management of the young child with early onset wheezing. Curr Opin Allergy Clin Immunol. 2017 Apr; 17(2):146-152. PMID: 28092287.
      View in: PubMed
    7. Hoch HE, Calatroni A, West JB, Liu AH, Gergen PJ, Gruchalla RS, Khurana Hershey GK, Kercsmar CM, Kim H, Lamm CI, Makhija MM, Mitchell HE, Teach SJ, Wildfire JJ, Busse WW, Szefler SJ. Can we predict fall asthma exacerbations? Validation of the seasonal asthma exacerbation index. J Allergy Clin Immunol. 2017 Feb 24. PMID: 28238748.
      View in: PubMed
    8. Szefler SJ, Murphy K, Harper T, Boner A, Laki I, Engel M, El Azzi G, Moroni-Zentgraf P, Finnigan H, Hamelmann E. A phase III randomized controlled trial of tiotropium add-on therapy in children with severe symptomatic asthma. J Allergy Clin Immunol. 2017 Feb 09. PMID: 28189771.
      View in: PubMed
    9. Hamelmann E, Vogelberg C, Szefler SJ. Tiotropium for the treatment of asthma in adolescents. Expert Opin Pharmacother. 2017 Feb; 18(3):305-312. PMID: 28110558.
      View in: PubMed
    10. Bacharier LB, Szefler SJ. Editorial: moving ahead faster than ever. Curr Opin Allergy Clin Immunol. 2017 Jan 30. PMID: 28141627.
      View in: PubMed
    11. Nyenhuis SM, Krishnan JA, Berry A, Calhoun WJ, Chinchilli VM, Engle L, Grossman N, Holguin F, Israel E, Kittles RA, Kraft M, Lazarus SC, Lehman EB, Mauger DT, Moy JN, Peters SP, Phipatanakul W, Smith LJ, Sumino K, Szefler SJ, Wechsler ME, Wenzel S, White SR, Ackerman SJ. Race is associated with differences in airway inflammation in patients with asthma. J Allergy Clin Immunol. 2016 Dec 31. PMID: 28069248.
      View in: PubMed
    12. McGeachie MJ, Yates KP, Zhou X, Guo F, Sternberg AL, Van Natta ML, Wise RA, Szefler SJ, Sharma S, Kho AT, Cho MH, Croteau-Chonka DC, Castaldi PJ, Jain G, Sanyal A, Zhan Y, Lajoie BR, Dekker J, Stamatoyannopoulos J, Covar RA, Zeiger RS, Adkinson NF, Williams PV, Kelly HW, Grasemann H, Vonk JM, Koppelman GH, Postma DS, Raby BA, Houston I, Lu Q, Fuhlbrigge AL, Tantisira KG, Silverman EK, Tonascia J, Strunk RC, Weiss ST. Genetics and Genomics of Longitudinal Lung Function Patterns in Individuals with Asthma. Am J Respir Crit Care Med. 2016 Dec 15; 194(12):1465-1474. PMID: 27367781.
      View in: PubMed
    13. Stempel DA, Szefler SJ, Pascoe SJ. Salmeterol and Fluticasone Propionate in Children with Asthma. N Engl J Med. 2016 12 01; 375(22):e46. PMID: 27959746.
      View in: PubMed
    14. Carr WW, Szefler SJ. Inhaled corticosteroids: Ocular safety and the hypothalamic-pituitary-adrenal axis. Ann Allergy Asthma Immunol. 2016 Dec; 117(6):589-594. PMID: 27979014.
      View in: PubMed
    15. Abrams EM, Szefler SJ, Becker AB. Effect of asthma therapies on the natural course of asthma. Ann Allergy Asthma Immunol. 2016 Dec; 117(6):627-633. PMID: 28073701.
      View in: PubMed
    16. Fitzpatrick AM, Jackson DJ, Mauger DT, Boehmer SJ, Phipatanakul W, Sheehan WJ, Moy JN, Paul IM, Bacharier LB, Cabana MD, Covar R, Holguin F, Lemanske RF, Martinez FD, Pongracic JA, Beigelman A, Baxi SN, Benson M, Blake K, Chmiel JF, Daines CL, Daines MO, Gaffin JM, Gentile DA, Gower WA, Israel E, Kumar HV, Lang JE, Lazarus SC, Lima JJ, Ly N, Marbin J, Morgan W, Myers RE, Olin JT, Peters SP, Raissy HH, Robison RG, Ross K, Sorkness CA, Thyne SM, Szefler SJ. Individualized therapy for persistent asthma in young children. J Allergy Clin Immunol. 2016 Dec; 138(6):1608-1618.e12. PMID: 27777180.
      View in: PubMed
    17. Yang IV, Pedersen BS, Liu AH, O'Connor GT, Pillai D, Kattan M, Misiak RT, Gruchalla R, Szefler SJ, Khurana Hershey GK, Kercsmar C, Richards A, Stevens AD, Kolakowski CA, Makhija M, Sorkness CA, Krouse RZ, Visness C, Davidson EJ, Hennessy CE, Martin RJ, Togias A, Busse WW, Schwartz DA. The nasal methylome and childhood atopic asthma. J Allergy Clin Immunol. 2017 May; 139(5):1478-1488. PMID: 27745942.
      View in: PubMed
    18. Liptzin DR, Szefler SJ. Evolution of Asthma Self-Management Programs in Adolescents: From the Crisis Plan to Facebook. J Pediatr. 2016 Dec; 179:19-23. PMID: 27745749.
      View in: PubMed
    19. Gleason M, Cicutto L, Haas-Howard C, Raleigh BM, Szefler SJ. Leveraging Partnerships: Families, Schools, and Providers Working Together to Improve Asthma Management. Curr Allergy Asthma Rep. 2016 Oct; 16(10):74. PMID: 27709456.
      View in: PubMed
    20. Spahn JD, Malka J, Szefler SJ. Current application of exhaled nitric oxide in clinical practice. J Allergy Clin Immunol. 2016 Nov; 138(5):1296-1298. PMID: 27664377.
      View in: PubMed
    21. Iribarren C, Rahmaoui A, Long AA, Szefler SJ, Bradley MS, Carrigan G, Eisner MD, Chen H, Omachi TA, Farkouh ME, Rothman KJ. Cardiovascular and cerebrovascular events among patients receiving omalizumab: Results from EXCELS, a prospective cohort study in moderate to severe asthma. J Allergy Clin Immunol. 2017 May; 139(5):1489-1495.e5. PMID: 27639934.
      View in: PubMed
    22. Lemanske RF, Kakumanu S, Shanovich K, Antos N, Cloutier MM, Mazyck D, Phipatanakul W, Schantz S, Szefler S, Vandlik R, Williams P. Creation and implementation of SAMPRO™: A school-based asthma management program. J Allergy Clin Immunol. 2016 Sep; 138(3):711-23. PMID: 27596707.
      View in: PubMed
    23. Stempel DA, Szefler SJ, Pedersen S, Zeiger RS, Yeakey AM, Lee LA, Liu AH, Mitchell H, Kral KM, Raphiou IH, Prillaman BA, Buaron KS, Yun Kirby S, Pascoe SJ. Safety of Adding Salmeterol to Fluticasone Propionate in Children with Asthma. N Engl J Med. 2016 Sep 01; 375(9):840-9. PMID: 27579634.
      View in: PubMed
    24. Sheehan WJ, Mauger DT, Paul IM, Moy JN, Boehmer SJ, Szefler SJ, Fitzpatrick AM, Jackson DJ, Bacharier LB, Cabana MD, Covar R, Holguin F, Lemanske RF, Martinez FD, Pongracic JA, Beigelman A, Baxi SN, Benson M, Blake K, Chmiel JF, Daines CL, Daines MO, Gaffin JM, Gentile DA, Gower WA, Israel E, Kumar HV, Lang JE, Lazarus SC, Lima JJ, Ly N, Marbin J, Morgan WJ, Myers RE, Olin JT, Peters SP, Raissy HH, Robison RG, Ross K, Sorkness CA, Thyne SM, Wechsler ME, Phipatanakul W. Acetaminophen versus Ibuprofen in Young Children with Mild Persistent Asthma. N Engl J Med. 2016 Aug 18; 375(7):619-30. PMID: 27532828.
      View in: PubMed
    25. Liu AH, Anderson WC, Dutmer CM, Searing DA, Szefler SJ. Advances in asthma 2015: Across the lifespan. J Allergy Clin Immunol. 2016 Aug; 138(2):397-404. PMID: 27497278.
      View in: PubMed
    26. Liptzin DR, Gleason MC, Cicutto LC, Cleveland CL, Shocks DJ, White MK, Faino AV, Szefler SJ. Developing, Implementing, and Evaluating a School-Centered Asthma Program: Step-Up Asthma Program. J Allergy Clin Immunol Pract. 2016 Sep-Oct; 4(5):972-979.e1. PMID: 27283054.
      View in: PubMed
    27. Federico MJ, Hoch HE, Anderson WC, Spahn JD, Szefler SJ. Asthma Management for Children: Risk Identification and Prevention. Adv Pediatr. 2016 Aug; 63(1):103-26. PMID: 27426897.
      View in: PubMed
    28. McGeachie MJ, Yates KP, Zhou X, Guo F, Sternberg AL, Van Natta ML, Wise RA, Szefler SJ, Sharma S, Kho AT, Cho MH, Croteau-Chonka DC, Castaldi PJ, Jain G, Sanyal A, Zhan Y, Lajoie BR, Dekker J, Stamatoyannopoulos J, Covar RA, Zeiger RS, Adkinson NF, Williams PV, Kelly HW, Grasemann H, Vonk JM, Koppelman GH, Postma DS, Raby BA, Houston I, Lu Q, Fuhlbrigge AL, Tantisira KG, Silverman EK, Tonascia J, Weiss ST, Strunk RC. Patterns of Growth and Decline in Lung Function in Persistent Childhood Asthma. N Engl J Med. 2016 May 12; 374(19):1842-52. PMID: 27168434; PMCID: PMC5032024 [Available on 11/12/16].
    29. Hamelmann E, Bateman ED, Vogelberg C, Szefler SJ, Vandewalker M, Moroni-Zentgraf P, Avis M, Unseld A, Engel M, Boner AL. Tiotropium add-on therapy in adolescents with moderate asthma: A 1-year randomized controlled trial. J Allergy Clin Immunol. 2016 Aug; 138(2):441-450.e8. PMID: 26960245.
      View in: PubMed
    30. Dunn R, Szefler SJ. Severe Asthma in Pediatric Patients. Pathophysiology and Unmet Needs. Ann Am Thorac Soc. 2016 Mar; 13 Suppl 1:S103-4. PMID: 27027942.
      View in: PubMed
    31. Kraft M, Gerber AN, Szefler SJ, Wechsler ME. Introduction to the 58th Annual Thomas L. Petty Aspen Lung Conference: Asthma 2015: Mechanisms to Personalized Medicine. Ann Am Thorac Soc. 2016 Mar; 13 Suppl 1:S23-4. PMID: 27027947.
      View in: PubMed
    32. Yang IV, Pedersen BS, Liu AH, O'Connor GT, Teach SJ, Kattan M, Misiak RT, Gruchalla R, Steinbach SF, Szefler SJ, Gill MA, Calatroni A, David G, Hennessy CE, Davidson EJ, Gergen P, Togias A, Busse WW, Schwartz DA. DNA Methylation Changes in Nasal Epithelia Are Associated with Allergic Asthma in the Inner City. Ann Am Thorac Soc. 2016 Mar; 13 Suppl 1:S99-S100. PMID: 27027970; PMCID: PMC5015744 [Available on 03/01/17].
    33. Dhami S, Nurmatov U, Agache I, Lau S, Muraro A, Jutel M, Roberts G, Akdis C, Bonini M, Calderon M, Casale T, Cavkaytar O, Cox L, Demoly P, Flood B, Hamelmann E, Izuhara K, Kalayci Ö, Kleine-Tebbe J, Nieto A, Papadopoulos N, Pfaar O, Rosenwasser L, Ryan D, Schmidt-Weber C, Szefler S, Wahn U, van Wijk RG, Wilkinson J, Sheikh A. Allergen immunotherapy for allergic asthma: protocol for a systematic review. Clin Transl Allergy. 2015; 6:5. PMID: 26862389; PMCID: PMC4746770.
    34. Cicutto L, Shocks D, Gleason M, Haas-Howard C, White M, Szefler SJ. Creating District Readiness for Implementing Evidence-Based School-Centered Asthma Programs: Denver Public Schools as a Case Study. NASN Sch Nurse. 2016 Mar; 31(2):112-8. PMID: 26822131.
      View in: PubMed
    35. Szefler SJ. Examining causes of the urban (inner city) asthma epidemic: Implementing new management strategies. Allergy Asthma Proc. 2016 Jan-Feb; 37(1):4-8. PMID: 26831839.
      View in: PubMed
    36. Bender BG, Krishnan JA, Chambers DA, Cloutier MM, Riekert KA, Rand CS, Schatz M, Thomson CC, Wilson SR, Apter A, Carson SS, George M, Gerald JK, Gerald L, Goss CH, Okelo SO, Mularski RA, Nguyen HQ, Patel MR, Szefler SJ, Weiss CH, Wilson KC, Freemer M. American Thoracic Society and National Heart, Lung, and Blood Institute Implementation Research Workshop Report. Ann Am Thorac Soc. 2015 Dec; 12(12):S213-21. PMID: 26653201.
      View in: PubMed
    37. Levy BD, Noel PJ, Freemer MM, Cloutier MM, Georas SN, Jarjour NN, Ober C, Woodruff PG, Barnes KC, Bender BG, Camargo CA, Chupp GL, Denlinger LC, Fahy JV, Fitzpatrick AM, Fuhlbrigge A, Gaston BM, Hartert TV, Kolls JK, Lynch SV, Moore WC, Morgan WJ, Nadeau KC, Ownby DR, Solway J, Szefler SJ, Wenzel SE, Wright RJ, Smith RA, Erzurum SC. Future Research Directions in Asthma. An NHLBI Working Group Report. Am J Respir Crit Care Med. 2015 Dec 01; 192(11):1366-72. PMID: 26305520; PMCID: PMC4731702 [Available on 12/01/16].
    38. Bacharier LB, Guilbert TW, Mauger DT, Boehmer S, Beigelman A, Fitzpatrick AM, Jackson DJ, Baxi SN, Benson M, Burnham CA, Cabana M, Castro M, Chmiel JF, Covar R, Daines M, Gaffin JM, Gentile DA, Holguin F, Israel E, Kelly HW, Lazarus SC, Lemanske RF, Ly N, Meade K, Morgan W, Moy J, Olin T, Peters SP, Phipatanakul W, Pongracic JA, Raissy HH, Ross K, Sheehan WJ, Sorkness C, Szefler SJ, Teague WG, Thyne S, Martinez FD. Early Administration of Azithromycin and Prevention of Severe Lower Respiratory Tract Illnesses in Preschool Children With a History of Such Illnesses: A Randomized Clinical Trial. JAMA. 2015 Nov 17; 314(19):2034-44. PMID: 26575060; PMCID: PMC4757487.
    39. Hoch HE, Szefler SJ. Intermittent steroid inhalation for the treatment of childhood asthma. Expert Rev Clin Immunol. 2016; 12(2):183-94. PMID: 26561351.
      View in: PubMed
    40. Teach SJ, Gill MA, Togias A, Sorkness CA, Arbes SJ, Calatroni A, Wildfire JJ, Gergen PJ, Cohen RT, Pongracic JA, Kercsmar CM, Khurana Hershey GK, Gruchalla RS, Liu AH, Zoratti EM, Kattan M, Grindle KA, Gern JE, Busse WW, Szefler SJ. Preseasonal treatment with either omalizumab or an inhaled corticosteroid boost to prevent fall asthma exacerbations. J Allergy Clin Immunol. 2015 Dec; 136(6):1476-85. PMID: 26518090.
      View in: PubMed
    41. Vogelberg C, Moroni-Zentgraf P, Leonaviciute-Klimantaviciene M, Sigmund R, Hamelmann E, Engel M, Szefler S. Erratum to: A randomised dose-ranging study of tiotropium Respimat® in children with symptomatic asthma despite inhaled corticosteroids. Respir Res. 2015 Oct 20; 16:128. PMID: 26487277; PMCID: PMC4618361.
    42. Dunn RM, Lehman E, Chinchilli VM, Martin RJ, Boushey HA, Israel E, Kraft M, Lazarus SC, Lemanske RF, Lugogo NL, Peters SP, Sorkness CA, Szefler S, Wechsler ME. Impact of Age and Sex on Response to Asthma Therapy. Am J Respir Crit Care Med. 2015 Sep 01; 192(5):551-8. PMID: 26068329; PMCID: PMC4595693.
    43. Anderson WC, Szefler SJ. New and future strategies to improve asthma control in children. J Allergy Clin Immunol. 2015 Oct; 136(4):848-59. PMID: 26318072.
      View in: PubMed
    44. Reddel HK, Bateman ED, Becker A, Boulet LP, Cruz AA, Drazen JM, Haahtela T, Hurd SS, Inoue H, de Jongste JC, Lemanske RF, Levy ML, O'Byrne PM, Paggiaro P, Pedersen SE, Pizzichini E, Soto-Quiroz M, Szefler SJ, Wong GW, FitzGerald JM. A summary of the new GINA strategy: a roadmap to asthma control. Eur Respir J. 2015 Sep; 46(3):622-39. PMID: 26206872; PMCID: PMC4554554.
    45. Brand PL, Mäkelä MJ, Szefler SJ, Frischer T, Price D. Monitoring asthma in childhood: symptoms, exacerbations and quality of life. Eur Respir Rev. 2015 Jun; 24(136):187-93. PMID: 26028631.
      View in: PubMed
    46. Meltzer LJ, Faino A, Szefler SJ, Strand M, Gelfand EW, Beebe DW. Experimentally manipulated sleep duration in adolescents with asthma: Feasibility and preliminary findings. Pediatr Pulmonol. 2015 Dec; 50(12):1360-7. PMID: 25872769; PMCID: PMC4785884 [Available on 12/01/16].
    47. Gerald JK, Gerald LB, Vasquez MM, Morgan WJ, Boehmer SJ, Lemanske RF, Mauger DT, Strunk RC, Szefler SJ, Zeiger RS, Bacharier LB, Bade E, Covar RA, Guilbert TW, Heidarian-Raissy H, Kelly HW, Malka-Rais J, Sorkness CA, Taussig LM, Chinchilli VM, Martinez FD. Markers of Differential Response to Inhaled Corticosteroid Treatment Among Children with Mild Persistent Asthma. J Allergy Clin Immunol Pract. 2015 Jul-Aug; 3(4):540-6.e3. PMID: 25783161; PMCID: PMC4500671.
    48. Yang IV, Pedersen BS, Liu A, O'Connor GT, Teach SJ, Kattan M, Misiak RT, Gruchalla R, Steinbach SF, Szefler SJ, Gill MA, Calatroni A, David G, Hennessy CE, Davidson EJ, Zhang W, Gergen P, Togias A, Busse WW, Schwartz DA. DNA methylation and childhood asthma in the inner city. J Allergy Clin Immunol. 2015 Jul; 136(1):69-80. PMID: 25769910; PMCID: PMC4494877.
    49. Pijnenburg MW, Baraldi E, Brand PL, Carlsen KH, Eber E, Frischer T, Hedlin G, Kulkarni N, Lex C, Mäkelä MJ, Mantzouranis E, Moeller A, Pavord I, Piacentini G, Price D, Rottier BL, Saglani S, Sly PD, Szefler SJ, Tonia T, Turner S, Wooler E, Lødrup Carlsen KC. Monitoring asthma in children. Eur Respir J. 2015 Apr; 45(4):906-25. PMID: 25745042.
      View in: PubMed
    50. Israel E, Lasky-Su J, Markezich A, Damask A, Szefler SJ, Schuemann B, Klanderman B, Sylvia J, Kazani S, Wu R, Martinez F, Boushey HA, Chinchilli VM, Mauger D, Weiss ST, Tantisira KG. Genome-wide association study of short-acting ß2-agonists. A novel genome-wide significant locus on chromosome 2 near ASB3. Am J Respir Crit Care Med. 2015 Mar 01; 191(5):530-7. PMID: 25562107; PMCID: PMC4384768.
    51. Vogelberg C, Moroni-Zentgraf P, Leonaviciute-Klimantaviciene M, Sigmund R, Hamelmann E, Engel M, Szefler S. A randomised dose-ranging study of tiotropium Respimat® in children with symptomatic asthma despite inhaled corticosteroids. Respir Res. 2015 Feb 07; 16:20. PMID: 25851298; PMCID: PMC4331449.
    52. Zemanick ET, Wagner BD, Robertson CE, Stevens MJ, Szefler SJ, Accurso FJ, Sagel SD, Harris JK. Assessment of airway microbiota and inflammation in cystic fibrosis using multiple sampling methods. Ann Am Thorac Soc. 2015 Feb; 12(2):221-9. PMID: 25474078; PMCID: PMC4342834.
    53. Szefler SJ. Advances in pediatric asthma in 2014: Moving toward a population health perspective. J Allergy Clin Immunol. 2015 Mar; 135(3):644-52. PMID: 25649079.
      View in: PubMed
    54. Szefler SJ. Monitoring and adherence in asthma management. Lancet Respir Med. 2015 Mar; 3(3):175-6. PMID: 25617214.
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    55. Wang Y, Tong C, Wang Z, Wang Z, Mauger D, Tantisira KG, Israel E, Szefler SJ, Chinchilli VM, Boushey HA, Lazarus SC, Lemanske RF, Wu R. Pharmacodynamic genome-wide association study identifies new responsive loci for glucocorticoid intervention in asthma. Pharmacogenomics J. 2015 Oct; 15(5):422-9. PMID: 25601762.
      View in: PubMed
    56. Cicutto L, Gleason M, Szefler SJ. Establishing school-centered asthma programs. J Allergy Clin Immunol. 2014 Dec; 134(6):1223-30; quiz 1231. PMID: 25482867.
      View in: PubMed
    57. Pijnenburg MW, Szefler S. Personalized medicine in children with asthma. Paediatr Respir Rev. 2015 Mar; 16(2):101-7. PMID: 25458797.
      View in: PubMed
    58. Long A, Rothman K, Chen H, Carrigan G, Szefler S. Reply: To PMID 24679845. J Allergy Clin Immunol. 2015 Jan; 135(1):289-90. PMID: 25441293.
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    59. Sharma S, Zhou X, Thibault DM, Himes BE, Liu A, Szefler SJ, Strunk R, Castro M, Hansel NN, Diette GB, Vonakis BM, Adkinson NF, Avila L, Soto-Quiros M, Barraza-Villareal A, Lemanske RF, Solway J, Krishnan J, White SR, Cheadle C, Berger AE, Fan J, Boorgula MP, Nicolae D, Gilliland F, Barnes K, London SJ, Martinez F, Ober C, Celedón JC, Carey VJ, Weiss ST, Raby BA. A genome-wide survey of CD4(+) lymphocyte regulatory genetic variants identifies novel asthma genes. J Allergy Clin Immunol. 2014 Nov; 134(5):1153-62. PMID: 24934276; PMCID: PMC4253878.
    60. Malka J, Mauger DT, Covar R, Rabinovitch N, Lemanske RF, Spahn JD, Strunk RC, Zeiger RS, Morgan WJ, Szefler SJ. Eczema and race as combined determinants for differential response to step-up asthma therapy. J Allergy Clin Immunol. 2014 Aug; 134(2):483-5. PMID: 24835502; PMCID: PMC4119870.
    61. Green AW, Goldstein S, Szefler SJ, Wanderer A, Weinberger M. In lasting tribute: Elliot F. Ellis, MD, 1929-2014. J Allergy Clin Immunol. 2014 May; 133(5):1504-5. PMID: 24892145.
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    62. Szefler SJ, Chmiel JF, Fitzpatrick AM, Giacoia G, Green TP, Jackson DJ, Nielsen HC, Phipatanakul W, Raissy HH. Reply: To PMID 24290281. J Allergy Clin Immunol. 2014 Jun; 133(6):1776-7. PMID: 24786239.
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    63. Meltzer LJ, Ullrich M, Szefler SJ. Sleep duration, sleep hygiene, and insomnia in adolescents with asthma. J Allergy Clin Immunol Pract. 2014 Sep-Oct; 2(5):562-9. PMID: 25213049; PMCID: PMC4163200.
    64. Beigelman A, Zeiger RS, Mauger D, Strunk RC, Jackson DJ, Martinez FD, Morgan WJ, Covar R, Szefler SJ, Taussig LM, Bacharier LB. The association between vitamin D status and the rate of exacerbations requiring oral corticosteroids in preschool children with recurrent wheezing. J Allergy Clin Immunol. 2014 May; 133(5):1489-92, 1492.e1-3. PMID: 24698320; PMCID: PMC4086617.
    65. Long A, Rahmaoui A, Rothman KJ, Guinan E, Eisner M, Bradley MS, Iribarren C, Chen H, Carrigan G, Rosén K, Szefler SJ. Incidence of malignancy in patients with moderate-to-severe asthma treated with or without omalizumab. J Allergy Clin Immunol. 2014 Sep; 134(3):560-567.e4. PMID: 24679845.
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    66. Szefler SJ. Advances in pediatric asthma in 2013: coordinating asthma care. J Allergy Clin Immunol. 2014 Mar; 133(3):654-61. PMID: 24581430; PMCID: PMC3969825.
    67. Park HW, Dahlin A, Tse S, Duan QL, Schuemann B, Martinez FD, Peters SP, Szefler SJ, Lima JJ, Kubo M, Tamari M, Tantisira KG. Genetic predictors associated with improvement of asthma symptoms in response to inhaled corticosteroids. J Allergy Clin Immunol. 2014 Mar; 133(3):664-9.e5. PMID: 24486069; PMCID: PMC4112383.
    68. Szefler SJ, Chmiel JF, Fitzpatrick AM, Giacoia G, Green TP, Jackson DJ, Nielsen HC, Phipatanakul W, Raissy HH. Asthma across the ages: knowledge gaps in childhood asthma. J Allergy Clin Immunol. 2014 Jan; 133(1):3-13; quiz 14. PMID: 24290281; PMCID: PMC3925634.
    69. Chang TS, Lemanske RF, Mauger DT, Fitzpatrick AM, Sorkness CA, Szefler SJ, Gangnon RE, Page CD, Jackson DJ. Childhood asthma clusters and response to therapy in clinical trials. J Allergy Clin Immunol. 2014 Feb; 133(2):363-9. PMID: 24139497; PMCID: PMC3960405.
    70. Rabinovitch N, Mauger DT, Reisdorph N, Covar R, Malka J, Lemanske RF, Morgan WJ, Guilbert TW, Zeiger RS, Bacharier LB, Szefler SJ. Predictors of asthma control and lung function responsiveness to step 3 therapy in children with uncontrolled asthma. J Allergy Clin Immunol. 2014 Feb; 133(2):350-6. PMID: 24084071; PMCID: PMC3960329.
    71. Peters SP, Bleecker ER, Kunselman SJ, Icitovic N, Moore WC, Pascual R, Ameredes BT, Boushey HA, Calhoun WJ, Castro M, Cherniack RM, Craig T, Denlinger LC, Engle LL, Dimango EA, Israel E, Kraft M, Lazarus SC, Lemanske RF, Lugogo N, Martin RJ, Meyers DA, Ramsdell J, Sorkness CA, Sutherland ER, Wasserman SI, Walter MJ, Wechsler ME, Chinchilli VM, Szefler SJ. Predictors of response to tiotropium versus salmeterol in asthmatic adults. J Allergy Clin Immunol. 2013 Nov; 132(5):1068-1074.e1. PMID: 24084072; PMCID: PMC3826080.
    72. Himes BE, Qiu W, Klanderman B, Ziniti J, Senter-Sylvia J, Szefler SJ, Lemanske RF, Zeiger RS, Strunk RC, Martinez FD, Boushey H, Chinchilli VM, Israel E, Mauger D, Koppelman GH, Nieuwenhuis MA, Postma DS, Vonk JM, Rafaels N, Hansel NN, Barnes K, Raby B, Tantisira KG, Weiss ST. ITGB5 and AGFG1 variants are associated with severity of airway responsiveness. BMC Med Genet. 2013 Aug 28; 14:86. PMID: 23984888; PMCID: PMC3765944.
    73. Raissy HH, Kelly HW, Harkins M, Szefler SJ. Inhaled corticosteroids in lung diseases. Am J Respir Crit Care Med. 2013 Apr 15; 187(8):798-803. PMID: 23370915; PMCID: PMC3707369.
    74. Li X, Hawkins GA, Ampleford EJ, Moore WC, Li H, Hastie AT, Howard TD, Boushey HA, Busse WW, Calhoun WJ, Castro M, Erzurum SC, Israel E, Lemanske RF, Szefler SJ, Wasserman SI, Wenzel SE, Peters SP, Meyers DA, Bleecker ER. Genome-wide association study identifies TH1 pathway genes associated with lung function in asthmatic patients. J Allergy Clin Immunol. 2013 Aug; 132(2):313-20.e15. PMID: 23541324; PMCID: PMC3746327.
    75. Sorkness CA, Wildfire JJ, Calatroni A, Mitchell HE, Busse WW, O'Connor GT, Pongracic JA, Ross K, Gill MA, Kattan M, Morgan WJ, Teach SJ, Gergen PJ, Liu AH, Szefler SJ. Reassessment of omalizumab-dosing strategies and pharmacodynamics in inner-city children and adolescents. J Allergy Clin Immunol Pract. 2013 Mar; 1(2):163-71. PMID: 24565455; PMCID: PMC4254887.
    76. Himes BE, Sheppard K, Berndt A, Leme AS, Myers RA, Gignoux CR, Levin AM, Gauderman WJ, Yang JJ, Mathias RA, Romieu I, Torgerson DG, Roth LA, Huntsman S, Eng C, Klanderman B, Ziniti J, Senter-Sylvia J, Szefler SJ, Lemanske RF, Zeiger RS, Strunk RC, Martinez FD, Boushey H, Chinchilli VM, Israel E, Mauger D, Koppelman GH, Postma DS, Nieuwenhuis MA, Vonk JM, Lima JJ, Irvin CG, Peters SP, Kubo M, Tamari M, Nakamura Y, Litonjua AA, Tantisira KG, Raby BA, Bleecker ER, Meyers DA, London SJ, Barnes KC, Gilliland FD, Williams LK, Burchard EG, Nicolae DL, Ober C, DeMeo DL, Silverman EK, Paigen B, Churchill G, Shapiro SD, Weiss ST. Integration of mouse and human genome-wide association data identifies KCNIP4 as an asthma gene. PLoS One. 2013; 8(2):e56179. PMID: 23457522; PMCID: PMC3572953.
    77. Szefler SJ, Busse WW. The long-acting ß-adrenergic agonist controversy in asthma: troublesome times! J Allergy Clin Immunol. 2012 Dec; 130(6):1256-9. PMID: 23195524.
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    78. Szefler SJ. Advances in pediatric asthma in 2012: moving toward asthma prevention. J Allergy Clin Immunol. 2013 Jan; 131(1):36-46. PMID: 23199603.
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    79. Denlinger LC, Manthei DM, Seibold MA, Ahn K, Bleecker E, Boushey HA, Calhoun WJ, Castro M, Chinchili VM, Fahy JV, Hawkins GA, Icitovic N, Israel E, Jarjour NN, King T, Kraft M, Lazarus SC, Lehman E, Martin RJ, Meyers DA, Peters SP, Sheerar D, Shi L, Sutherland ER, Szefler SJ, Wechsler ME, Sorkness CA, Lemanske RF. P2X7-regulated protection from exacerbations and loss of control is independent of asthma maintenance therapy. Am J Respir Crit Care Med. 2013 Jan 01; 187(1):28-33. PMID: 23144325; PMCID: PMC3570642.
    80. Szefler SJ, Carlsson LG, Uryniak T, Baker JW. Budesonide inhalation suspension versus montelukast in children aged 2 to 4 years with mild persistent asthma. J Allergy Clin Immunol Pract. 2013 Jan; 1(1):58-64. PMID: 24229823.
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    81. Tamesis GP, Covar RA, Strand M, Liu AH, Szefler SJ, Klinnert MD. Predictors for asthma at age 7 years for low-income children enrolled in the Childhood Asthma Prevention Study. J Pediatr. 2013 Mar; 162(3):536-542.e2. PMID: 23036483; PMCID: PMC3582795.
    82. Chipps BE, Zeiger RS, Dorenbaum A, Borish L, Wenzel SE, Miller DP, Hayden ML, Bleecker ER, Simons FE, Szefler SJ, Weiss ST, Haselkorn T. Assessment of asthma control and asthma exacerbations in the epidemiology and natural history of asthma: outcomes and treatment regimens (TENOR) observational cohort. Curr Respir Care Rep. 2012 Dec; 1(4):259-269. PMID: 23136642.
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    83. Calhoun WJ, Ameredes BT, King TS, Icitovic N, Bleecker ER, Castro M, Cherniack RM, Chinchilli VM, Craig T, Denlinger L, DiMango EA, Engle LL, Fahy JV, Grant JA, Israel E, Jarjour N, Kazani SD, Kraft M, Kunselman SJ, Lazarus SC, Lemanske RF, Lugogo N, Martin RJ, Meyers DA, Moore WC, Pascual R, Peters SP, Ramsdell J, Sorkness CA, Sutherland ER, Szefler SJ, Wasserman SI, Walter MJ, Wechsler ME, Boushey HA. Comparison of physician-, biomarker-, and symptom-based strategies for adjustment of inhaled corticosteroid therapy in adults with asthma: the BASALT randomized controlled trial. JAMA. 2012 Sep 12; 308(10):987-97. PMID: 22968888; PMCID: PMC3697088.
    84. Szefler SJ. Early asthma: stepping closer to primary prevention. J Allergy Clin Immunol. 2012 Aug; 130(2):308-10. PMID: 22846745.
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    85. Himes BE, Jiang X, Hu R, Wu AC, Lasky-Su JA, Klanderman BJ, Ziniti J, Senter-Sylvia J, Lima JJ, Irvin CG, Peters SP, Meyers DA, Bleecker ER, Kubo M, Tamari M, Nakamura Y, Szefler SJ, Lemanske RF, Zeiger RS, Strunk RC, Martinez FD, Hanrahan JP, Koppelman GH, Postma DS, Nieuwenhuis MA, Vonk JM, Panettieri RA, Markezich A, Israel E, Carey VJ, Tantisira KG, Litonjua AA, Lu Q, Weiss ST. Genome-wide association analysis in asthma subjects identifies SPATS2L as a novel bronchodilator response gene. PLoS Genet. 2012 Jul; 8(7):e1002824. PMID: 22792082; PMCID: PMC3390407.
    86. Papadopoulos NG, Arakawa H, Carlsen KH, Custovic A, Gern J, Lemanske R, Le Souef P, Mäkelä M, Roberts G, Wong G, Zar H, Akdis CA, Bacharier LB, Baraldi E, van Bever HP, de Blic J, Boner A, Burks W, Casale TB, Castro-Rodriguez JA, Chen YZ, El-Gamal YM, Everard ML, Frischer T, Geller M, Gereda J, Goh DY, Guilbert TW, Hedlin G, Heymann PW, Hong SJ, Hossny EM, Huang JL, Jackson DJ, de Jongste JC, Kalayci O, Aït-Khaled N, Kling S, Kuna P, Lau S, Ledford DK, Lee SI, Liu AH, Lockey RF, Lødrup-Carlsen K, Lötvall J, Morikawa A, Nieto A, Paramesh H, Pawankar R, Pohunek P, Pongracic J, Price D, Robertson C, Rosario N, Rossenwasser LJ, Sly PD, Stein R, Stick S, Szefler S, Taussig LM, Valovirta E, Vichyanond P, Wallace D, Weinberg E, Wennergren G, Wildhaber J, Zeiger RS. International consensus on (ICON) pediatric asthma. Allergy. 2012 Aug; 67(8):976-97. PMID: 22702533; PMCID: PMC4442800.
    87. Chipps BE, Zeiger RS, Borish L, Wenzel SE, Yegin A, Hayden ML, Miller DP, Bleecker ER, Simons FE, Szefler SJ, Weiss ST, Haselkorn T. Key findings and clinical implications from The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) study. J Allergy Clin Immunol. 2012 Aug; 130(2):332-42.e10. PMID: 22694932; PMCID: PMC3622643.
    88. Szefler SJ, Chinchilli VM, Israel E, Denlinger LC, Lemanske RF, Calhoun W, Peters SP. Key observations from the NHLBI Asthma Clinical Research Network. Thorax. 2012 May; 67(5):450-5. PMID: 22514237; PMCID: PMC3709602.
    89. Tantisira KG, Damask A, Szefler SJ, Schuemann B, Markezich A, Su J, Klanderman B, Sylvia J, Wu R, Martinez F, Boushey HA, Chinchilli VM, Mauger D, Weiss ST, Israel E. Genome-wide association identifies the T gene as a novel asthma pharmacogenetic locus. Am J Respir Crit Care Med. 2012 Jun 15; 185(12):1286-91. PMID: 22538805; PMCID: PMC3381232.
    90. Szefler SJ, Wenzel S, Brown R, Erzurum SC, Fahy JV, Hamilton RG, Hunt JF, Kita H, Liu AH, Panettieri RA, Schleimer RP, Minnicozzi M. Asthma outcomes: biomarkers. J Allergy Clin Immunol. 2012 Mar; 129(3 Suppl):S9-23. PMID: 22386512; PMCID: PMC3390196.
    91. Zeiger RS, Yegin A, Simons FE, Haselkorn T, Rasouliyan L, Szefler SJ, Chipps BE. Evaluation of the National Heart, Lung, and Blood Institute guidelines impairment domain for classifying asthma control and predicting asthma exacerbations. Ann Allergy Asthma Immunol. 2012 Feb; 108(2):81-7. PMID: 22289725.
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    92. Wildfire JJ, Gergen PJ, Sorkness CA, Mitchell HE, Calatroni A, Kattan M, Szefler SJ, Teach SJ, Bloomberg GR, Wood RA, Liu AH, Pongracic JA, Chmiel JF, Conroy K, Rivera-Sanchez Y, Busse WW, Morgan WJ. Development and validation of the Composite Asthma Severity Index--an outcome measure for use in children and adolescents. J Allergy Clin Immunol. 2012 Mar; 129(3):694-701. PMID: 22244599; PMCID: PMC3294274.
    93. Szefler SJ. Advances in pediatric asthma in 2011: moving forward. J Allergy Clin Immunol. 2012 Jan; 129(1):60-8. PMID: 22196525.
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    94. Zeiger RS, Mauger D, Bacharier LB, Guilbert TW, Martinez FD, Lemanske RF, Strunk RC, Covar R, Szefler SJ, Boehmer S, Jackson DJ, Sorkness CA, Gern JE, Kelly HW, Friedman NJ, Mellon MH, Schatz M, Morgan WJ, Chinchilli VM, Raissy HH, Bade E, Malka-Rais J, Beigelman A, Taussig LM. Daily or intermittent budesonide in preschool children with recurrent wheezing. N Engl J Med. 2011 Nov 24; 365(21):1990-2001. PMID: 22111718; PMCID: PMC3247621.
    95. Krishnan JA, Bender BG, Wamboldt FS, Szefler SJ, Adkinson NF, Zeiger RS, Wise RA, Bilderback AL, Rand CS. Adherence to inhaled corticosteroids: an ancillary study of the Childhood Asthma Management Program clinical trial. J Allergy Clin Immunol. 2012 Jan; 129(1):112-8. PMID: 22104610; PMCID: PMC3350797.
    96. Szefler SJ, Busse WW. Adding LABAs to inhaled glucocorticoids for asthma. N Engl J Med. 2011 Sep 29; 365(13):1260-1; author reply 1261. PMID: 21991913.
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    97. Tantisira KG, Lasky-Su J, Harada M, Murphy A, Litonjua AA, Himes BE, Lange C, Lazarus R, Sylvia J, Klanderman B, Duan QL, Qiu W, Hirota T, Martinez FD, Mauger D, Sorkness C, Szefler S, Lazarus SC, Lemanske RF, Peters SP, Lima JJ, Nakamura Y, Tamari M, Weiss ST. Genomewide association between GLCCI1 and response to glucocorticoid therapy in asthma. N Engl J Med. 2011 Sep 29; 365(13):1173-83. PMID: 21991891; PMCID: PMC3667396.
    98. Szefler SJ. Is it time to revise the asthma guidelines? J Allergy Clin Immunol. 2011 Nov; 128(5):937-8. PMID: 21943941; PMCID: PMC3205258.
    99. Szefler SJ. Personalised medicine for asthma management in pregnancy. Lancet. 2011 Sep 10; 378(9795):963-4. PMID: 21907846.
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    100. Horner CC, Mauger D, Strunk RC, Graber NJ, Lemanske RF, Sorkness CA, Szefler SJ, Zeiger RS, Taussig LM, Bacharier LB. Most nocturnal asthma symptoms occur outside of exacerbations and associate with morbidity. J Allergy Clin Immunol. 2011 Nov; 128(5):977-82.e1-2. PMID: 21855126; PMCID: PMC3408598.
    101. Wu R, Tong C, Wang Z, Mauger D, Tantisira K, Szefler SJ, Chinchilli VM, Israel E. A conceptual framework for pharmacodynamic genome-wide association studies in pharmacogenomics. Drug Discov Today. 2011 Oct; 16(19-20):884-90. PMID: 21920452; PMCID: PMC4029408.
    102. Szefler SJ, Dakhama A. New insights into asthma pathogenesis and treatment. Curr Opin Immunol. 2011 Dec; 23(6):801-7. PMID: 21840186.
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    103. Guilbert TW, Mauger DT, Allen DB, Zeiger RS, Lemanske RF, Szefler SJ, Strunk RC, Bacharier LB, Covar R, Sorkness CA, Taussig LM, Martinez FD. Growth of preschool children at high risk for asthma 2 years after discontinuation of fluticasone. J Allergy Clin Immunol. 2011 Nov; 128(5):956-63.e1-7. PMID: 21820163; PMCID: PMC3224818.
    104. Szefler SJ. Advancing asthma care: the glass is only half full! J Allergy Clin Immunol. 2011 Sep; 128(3):485-94. PMID: 21798579; PMCID: PMC3164913.
    105. Szefler SJ, Zeiger RS, Haselkorn T, Mink DR, Kamath TV, Fish JE, Chipps BE. Economic burden of impairment in children with severe or difficult-to-treat asthma. Ann Allergy Asthma Immunol. 2011 Aug; 107(2):110-119.e1. PMID: 21802018.
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    106. Busse WW, Morgan WJ, Gergen PJ, Mitchell HE, Gern JE, Liu AH, Gruchalla RS, Kattan M, Teach SJ, Pongracic JA, Chmiel JF, Steinbach SF, Calatroni A, Togias A, Thompson KM, Szefler SJ, Sorkness CA. Randomized trial of omalizumab (anti-IgE) for asthma in inner-city children. N Engl J Med. 2011 Mar 17; 364(11):1005-15. PMID: 21410369; PMCID: PMC3093964.
    107. Martinez FD, Chinchilli VM, Morgan WJ, Boehmer SJ, Lemanske RF, Mauger DT, Strunk RC, Szefler SJ, Zeiger RS, Bacharier LB, Bade E, Covar RA, Friedman NJ, Guilbert TW, Heidarian-Raissy H, Kelly HW, Malka-Rais J, Mellon MH, Sorkness CA, Taussig L. Use of beclomethasone dipropionate as rescue treatment for children with mild persistent asthma (TREXA): a randomised, double-blind, placebo-controlled trial. Lancet. 2011 Feb 19; 377(9766):650-7. PMID: 21324520; PMCID: PMC4852146.
    108. Sharma S, Murphy A, Howrylak J, Himes B, Cho MH, Chu JH, Hunninghake GM, Fuhlbrigge A, Klanderman B, Ziniti J, Senter-Sylvia J, Liu A, Szefler SJ, Strunk R, Castro M, Hansel NN, Diette GB, Vonakis BM, Adkinson NF, Carey VJ, Raby BA. The impact of self-identified race on epidemiologic studies of gene expression. Genet Epidemiol. 2011 Feb; 35(2):93-101. PMID: 21254216; PMCID: PMC3718033.
    109. Szefler SJ. Advances in pediatric asthma in 2010: addressing the major issues. J Allergy Clin Immunol. 2011 Jan; 127(1):102-15. PMID: 21211645; PMCID: PMC3032272.
    110. Wang L, Hollenbeak CS, Mauger DT, Zeiger RS, Paul IM, Sorkness CA, Lemanske RF, Martinez FD, Strunk RC, Szefler SJ, Taussig LM. Cost-effectiveness analysis of fluticasone versus montelukast in children with mild-to-moderate persistent asthma in the Pediatric Asthma Controller Trial. J Allergy Clin Immunol. 2011 Jan; 127(1):161-6, 166.e1. PMID: 21211651; PMCID: PMC3061816.
    111. Haselkorn T, Szefler SJ, Simons FE, Zeiger RS, Mink DR, Chipps BE, Borish L, Wong DA. Allergy, total serum immunoglobulin E, and airflow in children and adolescents in TENOR. Pediatr Allergy Immunol. 2010 Dec; 21(8):1157-65. PMID: 20444153.
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    112. Szefler SJ. Defining asthma phenotypes: focusing the picture. J Allergy Clin Immunol. 2010 Nov; 126(5):939-40. PMID: 21050941.
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    113. Sutherland ER, King TS, Icitovic N, Ameredes BT, Bleecker E, Boushey HA, Calhoun WJ, Castro M, Cherniack RM, Chinchilli VM, Craig TJ, Denlinger L, DiMango EA, Fahy JV, Israel E, Jarjour N, Kraft M, Lazarus SC, Lemanske RF, Peters SP, Ramsdell J, Sorkness CA, Szefler SJ, Walter MJ, Wasserman SI, Wechsler ME, Chu HW, Martin RJ. A trial of clarithromycin for the treatment of suboptimally controlled asthma. J Allergy Clin Immunol. 2010 Oct; 126(4):747-53. PMID: 20920764; PMCID: PMC2950827.
    114. Peters SP, Kunselman SJ, Icitovic N, Moore WC, Pascual R, Ameredes BT, Boushey HA, Calhoun WJ, Castro M, Cherniack RM, Craig T, Denlinger L, Engle LL, DiMango EA, Fahy JV, Israel E, Jarjour N, Kazani SD, Kraft M, Lazarus SC, Lemanske RF, Lugogo N, Martin RJ, Meyers DA, Ramsdell J, Sorkness CA, Sutherland ER, Szefler SJ, Wasserman SI, Walter MJ, Wechsler ME, Chinchilli VM, Bleecker ER. Tiotropium bromide step-up therapy for adults with uncontrolled asthma. N Engl J Med. 2010 Oct 28; 363(18):1715-26. PMID: 20979471; PMCID: PMC3011177.
    115. Murphy A, Chu JH, Xu M, Carey VJ, Lazarus R, Liu A, Szefler SJ, Strunk R, Demuth K, Castro M, Hansel NN, Diette GB, Vonakis BM, Adkinson NF, Klanderman BJ, Senter-Sylvia J, Ziniti J, Lange C, Pastinen T, Raby BA. Mapping of numerous disease-associated expression polymorphisms in primary peripheral blood CD4+ lymphocytes. Hum Mol Genet. 2010 Dec 01; 19(23):4745-57. PMID: 20833654; PMCID: PMC2972694.
    116. Leung DY, Szefler SJ. In utero smoke (IUS) exposure has been associated with increased prevalence of asthma and reduced lung function in healthy children. J Allergy Clin Immunol. 2010 Sep; 126(3):481-2. PMID: 20816183.
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    117. Rabinovitch N, Graber NJ, Chinchilli VM, Sorkness CA, Zeiger RS, Strunk RC, Bacharier LB, Martinez FD, Szefler SJ. Urinary leukotriene E4/exhaled nitric oxide ratio and montelukast response in childhood asthma. J Allergy Clin Immunol. 2010 Sep; 126(3):545-51.e1-4. PMID: 20816189; PMCID: PMC2935914.
    118. Simon MR, Chinchilli VM, Phillips BR, Sorkness CA, Lemanske RF, Szefler SJ, Taussig L, Bacharier LB, Morgan W. Forced expiratory flow between 25% and 75% of vital capacity and FEV1/forced vital capacity ratio in relation to clinical and physiological parameters in asthmatic children with normal FEV1 values. J Allergy Clin Immunol. 2010 Sep; 126(3):527-34.e1-8. PMID: 20638110; PMCID: PMC2933964.
    119. Covar R, Gleason M, Macomber B, Stewart L, Szefler P, Engelhardt K, Murphy J, Liu A, Wood S, DeMichele S, Gelfand EW, Szefler SJ. Impact of a novel nutritional formula on asthma control and biomarkers of allergic airway inflammation in children. Clin Exp Allergy. 2010 Aug; 40(8):1163-74. PMID: 20545703.
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    120. Lemanske RF, Mauger DT, Sorkness CA, Jackson DJ, Boehmer SJ, Martinez FD, Strunk RC, Szefler SJ, Zeiger RS, Bacharier LB, Covar RA, Guilbert TW, Larsen G, Morgan WJ, Moss MH, Spahn JD, Taussig LM. Step-up therapy for children with uncontrolled asthma receiving inhaled corticosteroids. N Engl J Med. 2010 Mar 18; 362(11):975-85. PMID: 20197425; PMCID: PMC2989902.
    121. Szefler SJ, Gergen PJ, Mitchell H, Morgan W. Achieving asthma control in the inner city: do the National Institutes of Health Asthma Guidelines really work? J Allergy Clin Immunol. 2010 Mar; 125(3):521-6; quiz 527-8. PMID: 20226288.
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    122. Kattan M, Kumar R, Bloomberg GR, Mitchell HE, Calatroni A, Gergen PJ, Kercsmar CM, Visness CM, Matsui EC, Steinbach SF, Szefler SJ, Sorkness CA, Morgan WJ, Teach SJ, Gan VN. Asthma control, adiposity, and adipokines among inner-city adolescents. J Allergy Clin Immunol. 2010 Mar; 125(3):584-92. PMID: 20226295; PMCID: PMC3596816.
    123. Covar RA, Strunk R, Zeiger RS, Wilson LA, Liu AH, Weiss S, Tonascia J, Spahn JD, Szefler SJ. Predictors of remitting, periodic, and persistent childhood asthma. J Allergy Clin Immunol. 2010 Feb; 125(2):359-366.e3. PMID: 20159245; PMCID: PMC2844768.
    124. Szefler SJ, Martin RJ. Lessons learned from variation in response to therapy in clinical trials. J Allergy Clin Immunol. 2010 Feb; 125(2):285-92; quiz 293-4. PMID: 20074785; PMCID: PMC2904979.
    125. Szefler SJ. Advances in pediatric asthma in 2009: gaining control of childhood asthma. J Allergy Clin Immunol. 2010 Jan; 125(1):69-78. PMID: 20109738.
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    126. Wechsler ME, Kunselman SJ, Chinchilli VM, Bleecker E, Boushey HA, Calhoun WJ, Ameredes BT, Castro M, Craig TJ, Denlinger L, Fahy JV, Jarjour N, Kazani S, Kim S, Kraft M, Lazarus SC, Lemanske RF, Markezich A, Martin RJ, Permaul P, Peters SP, Ramsdell J, Sorkness CA, Sutherland ER, Szefler SJ, Walter MJ, Wasserman SI, Israel E. Effect of beta2-adrenergic receptor polymorphism on response to longacting beta2 agonist in asthma (LARGE trial): a genotype-stratified, randomised, placebo-controlled, crossover trial. Lancet. 2009 Nov 21; 374(9703):1754-64. PMID: 19932356; PMCID: PMC2914569.
    127. Haselkorn T, Zeiger RS, Chipps BE, Mink DR, Szefler SJ, Simons FE, Massanari M, Fish JE. Recent asthma exacerbations predict future exacerbations in children with severe or difficult-to-treat asthma. J Allergy Clin Immunol. 2009 Nov; 124(5):921-7. PMID: 19895984.
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    128. Haselkorn T, Fish JE, Zeiger RS, Szefler SJ, Miller DP, Chipps BE, Simons FE, Weiss ST, Wenzel SE, Borish L, Bleecker ER. Consistently very poorly controlled asthma, as defined by the impairment domain of the Expert Panel Report 3 guidelines, increases risk for future severe asthma exacerbations in The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) study. J Allergy Clin Immunol. 2009 Nov; 124(5):895-902.e1-4. PMID: 19811812.
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    129. Long AA, Fish JE, Rahmaoui A, Miller MK, Bradley MS, Taki HN, Demeo AN, Tilles SA, Szefler SJ. Baseline characteristics of patients enrolled in EXCELS: a cohort study. Ann Allergy Asthma Immunol. 2009 Sep; 103(3):212-9. PMID: 19788018.
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    130. Rogers AJ, Tantisira KG, Fuhlbrigge AL, Litonjua AA, Lasky-Su JA, Szefler SJ, Strunk RC, Zeiger RS, Weiss ST. Predictors of poor response during asthma therapy differ with definition of outcome. Pharmacogenomics. 2009 Aug; 10(8):1231-42. PMID: 19663668; PMCID: PMC2746392.
    131. Gruchalla RS, Sampson HA, Matsui E, David G, Gergen PJ, Calatroni A, Brown M, Liu AH, Bloomberg GR, Chmiel JF, Kumar R, Lamm C, Smartt E, Sorkness CA, Steinbach SF, Stone KD, Szefler SJ, Busse WW. Asthma morbidity among inner-city adolescents receiving guidelines-based therapy: role of predictors in the setting of high adherence. J Allergy Clin Immunol. 2009 Aug; 124(2):213-21, 221.e1. PMID: 19615730; PMCID: PMC2757267.
    132. Kruzick T, Covar RA, Gleason M, Cicutto L, White M, Shocks D, Szefler SJ. Does access to care equal asthma control in school-age children? J Allergy Clin Immunol. 2009 Aug; 124(2):381-3. PMID: 19596141.
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    133. Szefler SJ. Managing asthma and allergies in schools: an opportunity to coordinate health care. J Allergy Clin Immunol. 2009 Aug; 124(2):201-4. PMID: 19596144.
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    134. Reddel HK, Taylor DR, Bateman ED, Boulet LP, Boushey HA, Busse WW, Casale TB, Chanez P, Enright PL, Gibson PG, de Jongste JC, Kerstjens HA, Lazarus SC, Levy ML, O'Byrne PM, Partridge MR, Pavord ID, Sears MR, Sterk PJ, Stoloff SW, Sullivan SD, Szefler SJ, Thomas MD, Wenzel SE. An official American Thoracic Society/European Respiratory Society statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials and clinical practice. Am J Respir Crit Care Med. 2009 Jul 01; 180(1):59-99. PMID: 19535666.
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    136. Strunk RC, Sternberg AL, Szefler SJ, Zeiger RS, Bender B, Tonascia J. Long-term budesonide or nedocromil treatment, once discontinued, does not alter the course of mild to moderate asthma in children and adolescents. J Pediatr. 2009 May; 154(5):682-7. PMID: 19167726; PMCID: PMC2942076.
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    139. Larsen GL, Morgan W, Heldt GP, Mauger DT, Boehmer SJ, Chinchilli VM, Lemanske RF, Martinez F, Strunk RC, Szefler SJ, Zeiger RS, Taussig LM, Bacharier LB, Guilbert TW, Radford S, Sorkness CA. Impulse oscillometry versus spirometry in a long-term study of controller therapy for pediatric asthma. J Allergy Clin Immunol. 2009 Apr; 123(4):861-7.e1. PMID: 19070356; PMCID: PMC4291457.
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    146. Walter MJ, Castro M, Kunselman SJ, Chinchilli VM, Reno M, Ramkumar TP, Avila PC, Boushey HA, Ameredes BT, Bleecker ER, Calhoun WJ, Cherniack RM, Craig TJ, Denlinger LC, Israel E, Fahy JV, Jarjour NN, Kraft M, Lazarus SC, Lemanske RF, Martin RJ, Peters SP, Ramsdell JW, Sorkness CA, Sutherland ER, Szefler SJ, Wasserman SI, Wechsler ME. Predicting worsening asthma control following the common cold. Eur Respir J. 2008 Dec; 32(6):1548-54. PMID: 18768579; PMCID: PMC2592508.
    147. Taylor DR, Bateman ED, Boulet LP, Boushey HA, Busse WW, Casale TB, Chanez P, Enright PL, Gibson PG, de Jongste JC, Kerstjens HA, Lazarus SC, Levy ML, O'Byrne PM, Partridge MR, Pavord ID, Sears MR, Sterk PJ, Stoloff SW, Szefler SJ, Sullivan SD, Thomas MD, Wenzel SE, Reddel HK. A new perspective on concepts of asthma severity and control. Eur Respir J. 2008 Sep; 32(3):545-54. PMID: 18757695.
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    148. Neville KA, Szefler SJ, Abdel-Rahman SM, Lahu G, Zech K, Herzog R, Bethke TD, Gleason MC, Kearns GL. Single-dose pharmacokinetics of roflumilast in children and adolescents. J Clin Pharmacol. 2008 Aug; 48(8):978-85. PMID: 18508947.
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    149. Wamboldt FS, Balkissoon RC, Rankin AE, Szefler SJ, Hammond SK, Glasgow RE, Dickinson WP. Correlates of household smoking bans in low-income families of children with and without asthma. Fam Process. 2008 Mar; 47(1):81-94. PMID: 18411831.
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    150. Szefler SJ. Asthma progression: can we and should we measure it? J Allergy Clin Immunol. 2008 Mar; 121(3):598-600. PMID: 18234308.
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    154. Bisgaard H, Szefler S. Prevalence of asthma-like symptoms in young children. Pediatr Pulmonol. 2007 Aug; 42(8):723-8. PMID: 17598172.
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    155. Spahn JD, Szefler SJ. Steroid therapy for asthma in children. Curr Opin Pediatr. 2007 Jun; 19(3):300-5. PMID: 17505190.
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    156. Chipps BE, Szefler SJ, Simons FE, Haselkorn T, Mink DR, Deniz Y, Lee JH. Demographic and clinical characteristics of children and adolescents with severe or difficult-to-treat asthma. J Allergy Clin Immunol. 2007 May; 119(5):1156-63. PMID: 17397912.
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    157. Szefler SJ. Advances in pediatric asthma 2006. J Allergy Clin Immunol. 2007 Mar; 119(3):558-62. PMID: 17270259.
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    158. Lazarus SC, Chinchilli VM, Rollings NJ, Boushey HA, Cherniack R, Craig TJ, Deykin A, DiMango E, Fish JE, Ford JG, Israel E, Kiley J, Kraft M, Lemanske RF, Leone FT, Martin RJ, Pesola GR, Peters SP, Sorkness CA, Szefler SJ, Wechsler ME, Fahy JV. Smoking affects response to inhaled corticosteroids or leukotriene receptor antagonists in asthma. Am J Respir Crit Care Med. 2007 Apr 15; 175(8):783-90. PMID: 17204725; PMCID: PMC1899291.
    159. Martin RJ, Szefler SJ, King TS, Kraft M, Boushey HA, Chinchilli VM, Craig TJ, Dimango EA, Deykin A, Fahy JV, Israel E, Lazarus SC, Lemanske RF, Leone FT, Pesola GR, Peters SP, Sorkness CA, Szwejbka LA, Wechsler ME. The Predicting Response to Inhaled Corticosteroid Efficacy (PRICE) trial. J Allergy Clin Immunol. 2007 Jan; 119(1):73-80. PMID: 17208587; PMCID: PMC2872157.
    160. Szefler SJ. A view from the bus: on the roadmap with the National Institutes of Health Asthma Networks. J Allergy Clin Immunol. 2007 Jan; 119(1):24-7. PMID: 17208584.
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    161. Sorkness CA, Lemanske RF, Mauger DT, Boehmer SJ, Chinchilli VM, Martinez FD, Strunk RC, Szefler SJ, Zeiger RS, Bacharier LB, Bloomberg GR, Covar RA, Guilbert TW, Heldt G, Larsen G, Mellon MH, Morgan WJ, Moss MH, Spahn JD, Taussig LM. Long-term comparison of 3 controller regimens for mild-moderate persistent childhood asthma: the Pediatric Asthma Controller Trial. J Allergy Clin Immunol. 2007 Jan; 119(1):64-72. PMID: 17140647.
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    162. Strunk RC, Weiss ST, Yates KP, Tonascia J, Zeiger RS, Szefler SJ. Mild to moderate asthma affects lung growth in children and adolescents. J Allergy Clin Immunol. 2006 Nov; 118(5):1040-7. PMID: 17088127.
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    163. Deykin A, Wechsler ME, Boushey HA, Chinchilli VM, Kunselman SJ, Craig TJ, DiMango E, Fahy JV, Kraft M, Leone F, Lazarus SC, Lemanske RF, Martin RJ, Pesola GR, Peters SP, Sorkness CA, Szefler SJ, Israel E. Combination therapy with a long-acting beta-agonist and a leukotriene antagonist in moderate asthma. Am J Respir Crit Care Med. 2007 Feb 01; 175(3):228-34. PMID: 16973987; PMCID: PMC1899264.
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    165. Tantisira KG, Fuhlbrigge AL, Tonascia J, Van Natta M, Zeiger RS, Strunk RC, Szefler SJ, Weiss ST. Bronchodilation and bronchoconstriction: predictors of future lung function in childhood asthma. J Allergy Clin Immunol. 2006 Jun; 117(6):1264-71. PMID: 16750985.
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    166. Spahn JD, Covar RA, Jain N, Gleason M, Shimamoto R, Szefler SJ, Gelfand EW. Effect of montelukast on peripheral airflow obstruction in children with asthma. Ann Allergy Asthma Immunol. 2006 Apr; 96(4):541-9. PMID: 16680924.
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    167. Walsh MC, Szefler S, Davis J, Allen M, Van Marter L, Abman S, Blackmon L, Jobe A. Summary proceedings from the bronchopulmonary dysplasia group. Pediatrics. 2006 Mar; 117(3 Pt 2):S52-6. PMID: 16777823.
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    168. Mjaanes CM, Whelan GJ, Szefler SJ. Corticosteroid therapy in asthma: predictors of responsiveness. Clin Chest Med. 2006 Mar; 27(1):119-32, vii. PMID: 16543057.
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    170. Wenzel S, Szefler SJ. Managing severe asthma. J Allergy Clin Immunol. 2006 Mar; 117(3):508-11. PMID: 16522447.
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    173. Szefler SJ, Whelan GJ, Leung DY. "Black box" warning: wake-up call or overreaction? J Allergy Clin Immunol. 2006 Jan; 117(1):26-9. PMID: 16387579.
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    174. Wechsler ME, Lehman E, Lazarus SC, Lemanske RF, Boushey HA, Deykin A, Fahy JV, Sorkness CA, Chinchilli VM, Craig TJ, DiMango E, Kraft M, Leone F, Martin RJ, Peters SP, Szefler SJ, Liu W, Israel E. beta-Adrenergic receptor polymorphisms and response to salmeterol. Am J Respir Crit Care Med. 2006 Mar 01; 173(5):519-26. PMID: 16322642; PMCID: PMC2662935.
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    176. Whelan GJ, Blumer JL, Martin RJ, Szefler SJ. Fluticasone propionate plasma concentration and systemic effect: effect of delivery device and duration of administration. J Allergy Clin Immunol. 2005 Sep; 116(3):525-30. PMID: 16159619.
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    177. Szefler S, Rohatagi S, Williams J, Lloyd M, Kundu S, Banerji D. Ciclesonide, a novel inhaled steroid, does not affect hypothalamic-pituitary-adrenal axis function in patients with moderate-to-severe persistent asthma. Chest. 2005 Sep; 128(3):1104-14. PMID: 16162694.
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    179. Szefler SJ. Airway remodeling: therapeutic target or not? Am J Respir Crit Care Med. 2005 Apr 01; 171(7):672-3. PMID: 15790863.
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    180. Covar RA, Cool C, Szefler SJ. Progression of asthma in childhood. J Allergy Clin Immunol. 2005 Apr; 115(4):700-7. PMID: 15805987.
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    183. Szefler SJ. Facing the challenges of childhood asthma: what changes are necessary? J Allergy Clin Immunol. 2005 Apr; 115(4):685-8. PMID: 15805985.
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    184. Szefler SJ, Apter A. Advances in pediatric and adult asthma. J Allergy Clin Immunol. 2005 Mar; 115(3):470-7. PMID: 15753890.
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    185. Covar RA, Macomber BA, Szefler SJ. Medications as asthma triggers. Immunol Allergy Clin North Am. 2005 Feb; 25(1):169-90. PMID: 15579370.
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    187. Colice GL, Stampone P, Leung DY, Szefler SJ. Oral corticosteroids in poorly controlled asthma. J Allergy Clin Immunol. 2005 Jan; 115(1):200-1. PMID: 15637569.
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    188. Guilbert TW, Morgan WJ, Zeiger RS, Bacharier LB, Boehmer SJ, Krawiec M, Larsen G, Lemanske RF, Liu A, Mauger DT, Sorkness C, Szefler SJ, Strunk RC, Taussig LM, Martinez FD. Atopic characteristics of children with recurrent wheezing at high risk for the development of childhood asthma. J Allergy Clin Immunol. 2004 Dec; 114(6):1282-7. PMID: 15577824.
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    189. Silkoff PE, Carlson M, Bourke T, Katial R, Ogren E, Szefler SJ. The Aerocrine exhaled nitric oxide monitoring system NIOX is cleared by the US Food and Drug Administration for monitoring therapy in asthma. J Allergy Clin Immunol. 2004 Nov; 114(5):1241-56. PMID: 15536442.
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    190. Israel E, Chinchilli VM, Ford JG, Boushey HA, Cherniack R, Craig TJ, Deykin A, Fagan JK, Fahy JV, Fish J, Kraft M, Kunselman SJ, Lazarus SC, Lemanske RF, Liggett SB, Martin RJ, Mitra N, Peters SP, Silverman E, Sorkness CA, Szefler SJ, Wechsler ME, Weiss ST, Drazen JM. Use of regularly scheduled albuterol treatment in asthma: genotype-stratified, randomised, placebo-controlled cross-over trial. Lancet. 2004 Oct 23-29; 364(9444):1505-12. PMID: 15500895.
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    191. Covar RA, Spahn JD, Martin RJ, Silkoff PE, Sundstrom DA, Murphy J, Szefler SJ. Safety and application of induced sputum analysis in childhood asthma. J Allergy Clin Immunol. 2004 Sep; 114(3):575-82. PMID: 15356559.
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    192. O'Connor SL, Bender BG, Gavin-Devitt LA, Wamboldt MZ, Milgrom H, Szefler S, Rand C, Wamboldt FS. Measuring adherence with the Doser CT in children with asthma. J Asthma. 2004 Sep; 41(6):663-70. PMID: 15584316.
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    193. Szefler SJ, Lyzell E, Fitzpatrick S, Cruz-Rivera M. Safety profile of budesonide inhalation suspension in the pediatric population: worldwide experience. Ann Allergy Asthma Immunol. 2004 Jul; 93(1):83-90. PMID: 15281476.
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    194. Guilbert TW, Morgan WJ, Krawiec M, Lemanske RF, Sorkness C, Szefler SJ, Larsen G, Spahn JD, Zeiger RS, Heldt G, Strunk RC, Bacharier LB, Bloomberg GR, Chinchilli VM, Boehmer SJ, Mauger EA, Mauger DT, Taussig LM, Martinez FD. The Prevention of Early Asthma in Kids study: design, rationale and methods for the Childhood Asthma Research and Education network. Control Clin Trials. 2004 Jun; 25(3):286-310. PMID: 15157730.
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    195. Szefler SJ. Current concepts in asthma treatment in children. Curr Opin Pediatr. 2004 Jun; 16(3):299-304. PMID: 15167017.
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    196. Covar RA, Spahn JD, Murphy JR, Szefler SJ. Progression of asthma measured by lung function in the childhood asthma management program. Am J Respir Crit Care Med. 2004 Aug 01; 170(3):234-41. PMID: 15028558.
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    197. Apter AJ, Szefler SJ. Advances in adult and pediatric asthma. J Allergy Clin Immunol. 2004 Mar; 113(3):407-14. PMID: 15007338.
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    198. Rohatagi S, Appajosyula S, Derendorf H, Szefler S, Nave R, Zech K, Banerji D. Risk-benefit value of inhaled glucocorticoids: a pharmacokinetic/pharmacodynamic perspective. J Clin Pharmacol. 2004 Jan; 44(1):37-47. PMID: 14681340.
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    199. Leone FT, Fish JE, Szefler SJ, West SL. Systematic review of the evidence regarding potential complications of inhaled corticosteroid use in asthma: collaboration of American College of Chest Physicians, American Academy of Allergy, Asthma, and Immunology, and American College of Allergy, Asthma, and Immunology. Chest. 2003 Dec; 124(6):2329-40. PMID: 14665517.
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    200. Szefler SJ, Whelan G, Gleason M, Spahn JD. The need for pediatric studies of allergy and asthma medications. Curr Allergy Asthma Rep. 2003 Nov; 3(6):478-83. PMID: 14531968.
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    201. Strunk RC, Szefler SJ, Phillips BR, Zeiger RS, Chinchilli VM, Larsen G, Hodgdon K, Morgan W, Sorkness CA, Lemanske RF. Relationship of exhaled nitric oxide to clinical and inflammatory markers of persistent asthma in children. J Allergy Clin Immunol. 2003 Nov; 112(5):883-92. PMID: 14610474.
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    202. Jenkins HA, Cherniack R, Szefler SJ, Covar R, Gelfand EW, Spahn JD. A comparison of the clinical characteristics of children and adults with severe asthma. Chest. 2003 Oct; 124(4):1318-24. PMID: 14555561.
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    203. Allen DB, Bielory L, Derendorf H, Dluhy R, Colice GL, Szefler SJ. Inhaled corticosteroids: past lessons and future issues. J Allergy Clin Immunol. 2003 Sep; 112(3 Suppl):S1-40. PMID: 14515117.
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    204. Bender BG, Ellison MC, Gleason M, Murphy JR, Sundstrom DA, Szefler SJ. Minimizing attrition in a long-term clinical trial of pediatric asthma. Ann Allergy Asthma Immunol. 2003 Aug; 91(2):168-76. PMID: 12952111.
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    205. Kraft M, Martin RJ, Lazarus SC, Fahy JV, Boushey HA, Lemanske RF, Szefler SJ. Airway tissue mast cells in persistent asthma: predictor of treatment failure when patients discontinue inhaled corticosteroids. Chest. 2003 Jul; 124(1):42-50. PMID: 12853500.
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    206. Szefler S, Pedersen S. Role of budesonide as maintenance therapy for children with asthma. Pediatr Pulmonol. 2003 Jul; 36(1):13-21. PMID: 12772218.
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    207. Jenkins HA, Cool C, Szefler SJ, Covar R, Brugman S, Gelfand EW, Spahn JD. Histopathology of severe childhood asthma: a case series. Chest. 2003 Jul; 124(1):32-41. PMID: 12853499.
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    208. Szefler SJ. Identifying the child in need of asthma therapy. Pediatr Clin North Am. 2003 Jun; 50(3):577-91. PMID: 12877237.
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    209. Casale TB, Blaiss MS, Gelfand E, Gilmore T, Harvey PD, Hindmarch I, Simons FE, Spangler DL, Szefler SJ, Terndrup TE, Waldman SA, Weiler J, Wong DF. First do no harm: managing antihistamine impairment in patients with allergic rhinitis. J Allergy Clin Immunol. 2003 May; 111(5):S835-42. PMID: 12743547.
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    210. Covar RA, Szefler SJ, Martin RJ, Sundstrom DA, Silkoff PE, Murphy J, Young DA, Spahn JD. Relations between exhaled nitric oxide and measures of disease activity among children with mild-to-moderate asthma. J Pediatr. 2003 May; 142(5):469-75. PMID: 12756375.
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    211. Liu AH, Szefler SJ. Advances in childhood asthma: hygiene hypothesis, natural history, and management. J Allergy Clin Immunol. 2003 Mar; 111(3 Suppl):S785-92. PMID: 12618744.
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    212. Szefler SJ. Pediatric asthma: an approach to pharmacogenetics analysis. Chest. 2003 Mar; 123(3 Suppl):434S-8S. PMID: 12629027.
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    213. Kelly HW, Strunk RC, Donithan M, Bloomberg GR, McWilliams BC, Szefler S. Growth and bone density in children with mild-moderate asthma: a cross-sectional study in children entering the Childhood Asthma Management Program (CAMP). J Pediatr. 2003 Mar; 142(3):286-91. PMID: 12640377.
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    214. Szefler SJ, Simoes EA. Montelukast for respiratory syncytial virus bronchiolitis: significant effect or provocative findings? Am J Respir Crit Care Med. 2003 Feb 01; 167(3):290-1. PMID: 12554617.
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    215. Strunk RC, Sternberg AL, Bacharier LB, Szefler SJ. Nocturnal awakening caused by asthma in children with mild-to-moderate asthma in the childhood asthma management program. J Allergy Clin Immunol. 2002 Sep; 110(3):395-403. PMID: 12209085.
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    216. Spahn JD, Szefler SJ. Inhaled steroids: are they all created equal? Semin Respir Crit Care Med. 2002 Aug; 23(4):377-86. PMID: 16088631.
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    217. Leung DY, Spahn JD, Szefler SJ. Steroid-unresponsive asthma. Semin Respir Crit Care Med. 2002 Aug; 23(4):387-98. PMID: 16088632.
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    218. Szefler SJ, Warner J, Staab D, Wahn U, Le Bourgeois M, van Essen-Zandvliet EE, Arora S, Pedersen S. Switching from conventional to extrafine aerosol beclomethasone dipropionate therapy in children: a 6-month, open- label, randomized trial. J Allergy Clin Immunol. 2002 Jul; 110(1):45-50. PMID: 12110818.
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    219. Wamboldt FS, Ho J, Milgrom H, Wamboldt MZ, Sanders B, Szefler SJ, Bender BG. Prevalence and correlates of household exposures to tobacco smoke and pets in children with asthma. J Pediatr. 2002 Jul; 141(1):109-15. PMID: 12091860.
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    220. Pedersen S, Warner J, Wahn U, Staab D, Le Bourgeois M, Van Essen-Zandvliet E, Arora S, Szefler SJ. Growth, systemic safety, and efficacy during 1 year of asthma treatment with different beclomethasone dipropionate formulations: an open-label, randomized comparison of extrafine and conventional aerosols in children. Pediatrics. 2002 Jun; 109(6):e92. PMID: 12042586.
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    221. Szefler SJ. Altering the course of asthma: Introduction. J Allergy Clin Immunol. 2002 Jun; 109(6 Suppl):S519-20. PMID: 12063506.
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    227. Spahn JD, Szefler SJ. Childhood asthma: new insights into management. J Allergy Clin Immunol. 2002 Jan; 109(1):3-13. PMID: 11799358.
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    228. Spahn JD, Fost DA, Covar R, Martin RJ, Brown EE, Szefler SJ, Leung DY. Clarithromycin potentiates glucocorticoid responsiveness in patients with asthma: results of a pilot study. Ann Allergy Asthma Immunol. 2001 Dec; 87(6):501-5. PMID: 11770698.
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    234. Leone FT, Mauger EA, Peters SP, Chinchilli VM, Fish JE, Boushey HA, Cherniack RM, Drazen JM, Fahy JV, Ford J, Israel E, Lazarus SC, Lemanske RF, Martin RJ, McGeady SJ, Sorkness C, Szefler SJ. The utility of peak flow, symptom scores, and beta-agonist use as outcome measures in asthma clinical research. Chest. 2001 Apr; 119(4):1027-33. PMID: 11296165.
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    236. Israel E, Drazen JM, Liggett SB, Boushey HA, Cherniack RM, Chinchilli VM, Cooper DM, Fahy JV, Fish JE, Ford JG, Kraft M, Kunselman S, Lazarus SC, Lemanske RF, Martin RJ, McLean DE, Peters SP, Silverman EK, Sorkness CA, Szefler SJ, Weiss ST, Yandava CN. Effect of polymorphism of the beta(2)-adrenergic receptor on response to regular use of albuterol in asthma. Int Arch Allergy Immunol. 2001 Jan-Mar; 124(1-3):183-6. PMID: 11306963.
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    237. Wamboldt MZ, Bihun JT, Szefler S, Hewitt J. Perception of induced bronchoconstriction in a community sample of adolescents. J Allergy Clin Immunol. 2000 Dec; 106(6):1102-7. PMID: 11112893.
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    238. Vanden Burgt JA, Busse WW, Martin RJ, Szefler SJ, Donnell D. Efficacy and safety overview of a new inhaled corticosteroid, QVAR (hydrofluoroalkane-beclomethasone extrafine inhalation aerosol), in asthma. J Allergy Clin Immunol. 2000 Dec; 106(6):1209-26. PMID: 11112914.
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    239. Bender B, Wamboldt FS, O'Connor SL, Rand C, Szefler S, Milgrom H, Wamboldt MZ. Measurement of children's asthma medication adherence by self report, mother report, canister weight, and Doser CT. Ann Allergy Asthma Immunol. 2000 Nov; 85(5):416-21. PMID: 11101187.
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    240. Szefler S, Weiss S, Tonascia J, Adkinson NF, Bender B, Cherniack R, Donithan M, Kelly HW, Reisman J, Shapiro GG, Sternberg AL, Strunk R, Taggart V, Van Natta M, Wise R, Wu M, Zeiger R. Long-term effects of budesonide or nedocromil in children with asthma. N Engl J Med. 2000 10 12; 343(15):1054-63. PMID: 11027739.
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    241. Szefler SJ. The changing faces of asthma. J Allergy Clin Immunol. 2000 Sep; 106(3 Suppl):S139-43. PMID: 10984394.
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    242. Israel E, Drazen JM, Liggett SB, Boushey HA, Cherniack RM, Chinchilli VM, Cooper DM, Fahy JV, Fish JE, Ford JG, Kraft M, Kunselman S, Lazarus SC, Lemanske RF, Martin RJ, McLean DE, Peters SP, Silverman EK, Sorkness CA, Szefler SJ, Weiss ST, Yandava CN. The effect of polymorphisms of the beta(2)-adrenergic receptor on the response to regular use of albuterol in asthma. Am J Respir Crit Care Med. 2000 Jul; 162(1):75-80. PMID: 10903223.
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    243. Skoner DP, Szefler SJ, Welch M, Walton-Bowen K, Cruz-Rivera M, Smith JA. Longitudinal growth in infants and young children treated with budesonide inhalation suspension for persistent asthma. J Allergy Clin Immunol. 2000 Feb; 105(2 Pt 1):259-68. PMID: 10669845.
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    244. Szefler SJ. Asthma: the new advances. Adv Pediatr. 2000; 47:273-308. PMID: 10959447.
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    245. Szefler SJ. Meeting needs of infants and young children with asthma: new developments in nebulized corticosteroid therapy. Introduction. J Allergy Clin Immunol. 1999 Oct; 104(4 Pt 2):159-61. PMID: 10518841.
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    246. Szefler SJ. Clinical need for a nebulized corticosteroid. J Allergy Clin Immunol. 1999 Oct; 104(4 Pt 2):162-8. PMID: 10518842.
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    247. Nelson HS, Szefler SJ, Jacobs J, Huss K, Shapiro G, Sternberg AL. The relationships among environmental allergen sensitization, allergen exposure, pulmonary function, and bronchial hyperresponsiveness in the Childhood Asthma Management Program. J Allergy Clin Immunol. 1999 Oct; 104(4 Pt 1):775-85. PMID: 10518821.
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    248. Szefler SJ. Pharmacodynamics and pharmacokinetics of budesonide: a new nebulized corticosteroid. J Allergy Clin Immunol. 1999 Oct; 104(4 Pt 2):175-83. PMID: 10518844.
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    249. Kemp JP, Skoner DP, Szefler SJ, Walton-Bowen K, Cruz-Rivera M, Smith JA. Once-daily budesonide inhalation suspension for the treatment of persistent asthma in infants and young children. Ann Allergy Asthma Immunol. 1999 Sep; 83(3):231-9. PMID: 10507269.
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    250. Wamboldt FS, Spahn JD, Klinnert MD, Wamboldt MZ, Gavin LA, Szefler SJ, Leung DY. Clinical outcomes of steroid-insensitive asthma. Ann Allergy Asthma Immunol. 1999 Jul; 83(1):55-60. PMID: 10437817.
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    251. Hauk PJ, Wenzel SE, Trumble AE, Szefler SJ, Leung DY. Increased T-cell receptor vbeta8+ T cells in bronchoalveolar lavage fluid of subjects with poorly controlled asthma: a potential role for microbial superantigens. J Allergy Clin Immunol. 1999 Jul; 104(1):37-45. PMID: 10400837.
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    252. Wamboldt FS, Bender BG, O'Connor SL, Gavin LA, Wamboldt MZ, Milgrom H, Szefler SJ, Iklé D, Rand C. Reliability of the model MC-311 MDI chronolog. J Allergy Clin Immunol. 1999 Jul; 104(1):53-7. PMID: 10400839.
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    253. Fost DA, Leung DY, Martin RJ, Brown EE, Szefler SJ, Spahn JD. Inhibition of methylprednisolone elimination in the presence of clarithromycin therapy. J Allergy Clin Immunol. 1999 Jun; 103(6):1031-5. PMID: 10359882.
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    254. Hamid QA, Wenzel SE, Hauk PJ, Tsicopoulos A, Wallaert B, Lafitte JJ, Chrousos GP, Szefler SJ, Leung DY. Increased glucocorticoid receptor beta in airway cells of glucocorticoid-insensitive asthma. Am J Respir Crit Care Med. 1999 May; 159(5 Pt 1):1600-4. PMID: 10228133.
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    255. Szefler SJ, Boushey HA, Pearlman DS, Togias A, Liddle R, Furlong A, Shah T, Knobil K. Time to onset of effect of fluticasone propionate in patients with asthma. J Allergy Clin Immunol. 1999 May; 103(5 Pt 1):780-8. PMID: 10329810.
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    256. Spahn JD, Leung DY, Chan MT, Szefler SJ, Gelfand EW. Mechanisms of glucocorticoid reduction in asthmatic subjects treated with intravenous immunoglobulin. J Allergy Clin Immunol. 1999 Mar; 103(3 Pt 1):421-6. PMID: 10069875.
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    257. Szefler SJ. Corticosteroid treatment of asthma: now at the crossroads. Reply to Drs Seale and Donnelly. Respir Med. 1999 Feb; 93(2):142-4. PMID: 10507939.
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    258. Leung DY, Spahn JD, Szefler SJ. Immunologic basis and management of steroid-resistant asthma. Allergy Asthma Proc. 1999 Jan-Feb; 20(1):9-14. PMID: 10076704.
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    259. Chu HW, Halliday JL, Martin RJ, Leung DY, Szefler SJ, Wenzel SE. Collagen deposition in large airways may not differentiate severe asthma from milder forms of the disease. Am J Respir Crit Care Med. 1998 Dec; 158(6):1936-44. PMID: 9847289.
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    260. Szefler SJ. Early intervention for childhood asthma: inhaled glucocorticoids as the "preferred" medication. J Allergy Clin Immunol. 1998 Nov; 102(5):719-21. PMID: 9819286.
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    261. Szefler SJ, Nelson HS. Alternative agents for anti-inflammatory treatment of asthma. J Allergy Clin Immunol. 1998 Oct; 102(4 Pt 2):S23-35. PMID: 9798721.
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    262. Szefler SJ. Leukotriene modifiers: what is their position in asthma therapy? J Allergy Clin Immunol. 1998 Aug; 102(2):170-2. PMID: 9723656.
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    263. Pedersen S, Szefler S. Pharmacological interventions. Childhood asthma. Eur Respir J Suppl. 1998 Jul; 27:40s-45s. PMID: 9699783.
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    264. Nimmagadda SR, Spahn JD, Nelson HS, Jenkins J, Szefler SJ, Leung DY. Fluticasone propionate results in improved glucocorticoid receptor binding affinity and reduced oral glucocorticoid requirements in severe asthma. Ann Allergy Asthma Immunol. 1998 Jul; 81(1):35-40. PMID: 9690571.
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    265. Shapiro G, Bronsky EA, LaForce CF, Mendelson L, Pearlman D, Schwartz RH, Szefler SJ. Dose-related efficacy of budesonide administered via a dry powder inhaler in the treatment of children with moderate to severe persistent asthma. J Pediatr. 1998 Jun; 132(6):976-82. PMID: 9627589.
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    266. Chan MT, Leung DY, Szefler SJ, Spahn JD. Difficult-to-control asthma: clinical characteristics of steroid-insensitive asthma. J Allergy Clin Immunol. 1998 May; 101(5):594-601. PMID: 9600494.
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    267. Leung DY, de Castro M, Szefler SJ, Chrousos GP. Mechanisms of glucocorticoid-resistant asthma. Ann N Y Acad Sci. 1998 May 01; 840:735-46. PMID: 9629300.
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    268. Leung DY, Szefler SJ. New insights into steroid resistant asthma. Pediatr Allergy Immunol. 1998 Feb; 9(1):3-12. PMID: 9560836.
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    269. Kamada AK, Szefler SJ. The safety of inhaled corticosteroid therapy in children. Curr Opin Pediatr. 1997 Dec; 9(6):585-9. PMID: 9425592.
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    270. Leung DY, Hamid Q, Vottero A, Szefler SJ, Surs W, Minshall E, Chrousos GP, Klemm DJ. Association of glucocorticoid insensitivity with increased expression of glucocorticoid receptor beta. J Exp Med. 1997 Nov 03; 186(9):1567-74. PMID: 9348314; PMCID: PMC2199113.
    271. Lanz MJ, Leung DY, McCormick DR, Harbeck R, Szefler SJ, White CW. Comparison of exhaled nitric oxide, serum eosinophilic cationic protein, and soluble interleukin-2 receptor in exacerbations of pediatric asthma. Pediatr Pulmonol. 1997 Nov; 24(5):305-11. PMID: 9407562.
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    272. Fish JE, Peters SP, Chambers CV, McGeady SJ, Epstein KR, Boushey HA, Cherniack RM, Chinchilli VM, Drazen JM, Fahy JV, Hurd SS, Israel E, Lazarus SC, Lemanske RF, Martin RJ, Mauger EA, Sorkness C, Szefler SJ. An evaluation of colchicine as an alternative to inhaled corticosteriods in moderate asthma. National Heart, Lung, and Blood Institute's Asthma Clinical Research Network. Am J Respir Crit Care Med. 1997 Oct; 156(4 Pt 1):1165-71. PMID: 9351617.
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    273. Leung DY, Szefler SJ. Diagnosis and management of steroid-resistant asthma. Clin Chest Med. 1997 Sep; 18(3):611-25. PMID: 9329880.
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    274. Wenzel SE, Szefler SJ, Leung DY, Sloan SI, Rex MD, Martin RJ. Bronchoscopic evaluation of severe asthma. Persistent inflammation associated with high dose glucocorticoids. Am J Respir Crit Care Med. 1997 Sep; 156(3 Pt 1):737-43. PMID: 9309987.
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    275. Szefler SJ, Leung DY. Glucocorticoid-resistant asthma: pathogenesis and clinical implications for management. Eur Respir J. 1997 Jul; 10(7):1640-7. PMID: 9230260.
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    276. Kamada AK, Szefler SJ. How should inhaled glucocorticoids be compared? J Allergy Clin Immunol. 1997 Jun; 99(6 Pt 1):735-7. PMID: 9215238.
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    277. Kamada AK, Wiener MB, LaVallee NM, Scott MB, Selner JC, Szefler SJ. A pharmacokinetic comparison of two oral liquid glucocorticoid formulations. Pharmacotherapy. 1997 Mar-Apr; 17(2):353-6. PMID: 9085328.
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    278. Nimmagadda SR, Szefler SJ, Spahn JD, Surs W, Leung DY. Allergen exposure decreases glucocorticoid receptor binding affinity and steroid responsiveness in atopic asthmatics. Am J Respir Crit Care Med. 1997 Jan; 155(1):87-93. PMID: 9001294.
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    279. Spahn JD, Leung DY, Szefler SJ. New insights into the pathogenesis and management of steroid-resistant asthma. J Asthma. 1997; 34(3):177-94. PMID: 9168845.
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    280. Spahn JD, Szefler SJ. The etiology and control of bronchial hyperresponsiveness in children. Curr Opin Pediatr. 1996 Dec; 8(6):591-6. PMID: 9018442.
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    281. Spahn JD, Landwehr LP, Nimmagadda S, Surs W, Leung DY, Szefler SJ. Effects of glucocorticoids on lymphocyte activation in patients with steroid-sensitive and steroid-resistant asthma. J Allergy Clin Immunol. 1996 Dec; 98(6 Pt 1):1073-9. PMID: 8977508.
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    282. Nimmagadda SR, Spahn JD, Leung DY, Szefler SJ. Steroid-resistant asthma: evaluation and management. Ann Allergy Asthma Immunol. 1996 Nov; 77(5):345-55; quiz 355-6. PMID: 8933772.
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    283. Drazen JM, Israel E, Boushey HA, Chinchilli VM, Fahy JV, Fish JE, Lazarus SC, Lemanske RF, Martin RJ, Peters SP, Sorkness C, Szefler SJ. Comparison of regularly scheduled with as-needed use of albuterol in mild asthma. Asthma Clinical Research Network. N Engl J Med. 1996 Sep 19; 335(12):841-7. PMID: 8778601.
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    284. Spahn JD, Szefler SJ, Surs W, Doherty DE, Nimmagadda SR, Leung DY. A novel action of IL-13: induction of diminished monocyte glucocorticoid receptor-binding affinity. J Immunol. 1996 Sep 15; 157(6):2654-9. PMID: 8805670.
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    285. Leung DY, Spahn JD, Nimmagadda SR, Szefler SJ. Induction of corticosteroid resistance in vitro. Am J Respir Crit Care Med. 1996 Aug; 154(2 Pt 2):S34-7; discussion S37-8. PMID: 8756785.
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    286. Kamada AK, Szefler SJ. The role of theophylline in the treatment of asthma. Ann Allergy Asthma Immunol. 1996 Jul; 77(1):1-3. PMID: 8705629.
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    287. Kamada AK, Szefler SJ, Martin RJ, Boushey HA, Chinchilli VM, Drazen JM, Fish JE, Israel E, Lazarus SC, Lemanske RF. Issues in the use of inhaled glucocorticoids. The Asthma Clinical Research Network. Am J Respir Crit Care Med. 1996 Jun; 153(6 Pt 1):1739-48. PMID: 8665030.
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    288. Stempel DA, Szefler SJ. Going beyond the National Asthma Education Program guidelines for the diagnosis and management of asthma: critical need for outcomes assessment. Ann Allergy Asthma Immunol. 1995 Dec; 75(6 Pt 1):457-60. PMID: 8603272.
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    289. Clayton MH, Leung DY, Surs W, Szefler SJ. Altered glucocorticoid receptor binding in atopic dermatitis. J Allergy Clin Immunol. 1995 Sep; 96(3):421-3. PMID: 7560645.
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    290. Kamada AK, Szefler SJ. Glucocorticoids and growth in asthmatic children. Pediatr Allergy Immunol. 1995 Aug; 6(3):145-54. PMID: 8750310.
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    291. Szefler SJ, Bender BG, Jusko WJ, Lanier BQ, Lemanske RF, Skoner DP, Stempel DA. Evolving role of theophylline for treatment of chronic childhood asthma. J Pediatr. 1995 Aug; 127(2):176-85. PMID: 7636640.
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    292. Pincus DJ, Szefler SJ, Ackerson LM, Martin RJ. Chronotherapy of asthma with inhaled steroids: the effect of dosage timing on drug efficacy. J Allergy Clin Immunol. 1995 Jun; 95(6):1172-8. PMID: 7797785.
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    293. Spahn JD, Leung DY, Surs W, Harbeck RJ, Nimmagadda S, Szefler SJ. Reduced glucocorticoid binding affinity in asthma is related to ongoing allergic inflammation. Am J Respir Crit Care Med. 1995 Jun; 151(6):1709-14. PMID: 7767511.
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    294. Leflein J, Brown E, Hill M, Kelly HW, Loffert DT, Nelson HS, Szefler SJ. Delivery of glucocorticoids by jet nebulization: aerosol characteristics and output. J Allergy Clin Immunol. 1995 May; 95(5 Pt 1):944-9. PMID: 7751514.
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    295. Leung DY, Martin RJ, Szefler SJ, Sher ER, Ying S, Kay AB, Hamid Q. Dysregulation of interleukin 4, interleukin 5, and interferon gamma gene expression in steroid-resistant asthma. J Exp Med. 1995 Jan 01; 181(1):33-40. PMID: 7807013; PMCID: PMC2191836.
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    297. Sher ER, Leung DY, Surs W, Kam JC, Zieg G, Kamada AK, Szefler SJ. Steroid-resistant asthma. Cellular mechanisms contributing to inadequate response to glucocorticoid therapy. J Clin Invest. 1994 Jan; 93(1):33-9. PMID: 8282803; PMCID: PMC293719.
    298. Kam JC, Szefler SJ, Surs W, Sher ER, Leung DY. Combination IL-2 and IL-4 reduces glucocorticoid receptor-binding affinity and T cell response to glucocorticoids. J Immunol. 1993 Oct 01; 151(7):3460-6. PMID: 8376786.
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    299. Kamada AK, Hill MR, Iklé DN, Brenner AM, Szefler SJ. Efficacy and safety of low-dose troleandomycin therapy in children with severe, steroid-requiring asthma. J Allergy Clin Immunol. 1993 Apr; 91(4):873-82. PMID: 8473676.
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    300. Stempel DA, Szefler SJ. Management of chronic asthma. Pediatr Clin North Am. 1992 Dec; 39(6):1293-310. PMID: 1331944.
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    301. Hill M, Szefler SJ, Larsen GL. Asthma pathogenesis and the implications for therapy in children. Pediatr Clin North Am. 1992 Dec; 39(6):1205-24. PMID: 1437316.
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    302. Kamada AK, Leung DY, Szefler SJ. Steroid resistance in asthma: our current understanding. Pediatr Pulmonol. 1992 Nov; 14(3):180-6. PMID: 1480444.
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    303. Kamada AK, Leung DY, Gleason MC, Hill MR, Szefler SJ. High-dose systemic glucocorticoid therapy in the treatment of severe asthma: a case of resistance and patterns of response. J Allergy Clin Immunol. 1992 Oct; 90(4 Pt 1):685-7. PMID: 1401649.
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    304. Kamada AK, Szefler SJ. Inhaled therapy in infants: why not nebulize glucocorticoids? Pediatr Pulmonol. 1992 Aug; 13(4):198-9. PMID: 1523026.
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    305. Szefler SJ. Anti-inflammatory drugs in the treatment of allergic disease. Med Clin North Am. 1992 Jul; 76(4):953-75. PMID: 1351972.
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    306. Altman LC, Findlay SR, Lopez M, Lukacsko P, Morris RJ, Pinnas JL, Ratner PH, Szefler SJ, Welch MJ. Adrenal function in adult asthmatics during long-term daily treatment with 800, 1,200, and 1,600 micrograms triamcinolone acetonide. Multicenter study. Chest. 1992 May; 101(5):1250-6. PMID: 1582280.
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    307. Dove AM, Szefler SJ, Hill MR, Jusko WJ, Larsen GL, Accurso FJ. Altered prednisolone pharmacokinetics in patients with cystic fibrosis. J Pediatr. 1992 May; 120(5):789-94. PMID: 1578318.
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    308. Alvarez J, Surs W, Leung DY, Iklé D, Gelfand EW, Szefler SJ. Steroid-resistant asthma: immunologic and pharmacologic features. J Allergy Clin Immunol. 1992 Mar; 89(3):714-21. PMID: 1545093.
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    309. Kamada AK, Parks DP, Szefler SJ. Inhaled glucocorticoid therapy in children: how much is safe? Pediatr Pulmonol. 1992 Feb; 12(2):71-2. PMID: 1570191.
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    310. Hendeles L, Weinberger M, Szefler S, Ellis E. Safety and efficacy of theophylline in children with asthma. J Pediatr. 1992 Feb; 120(2 Pt 1):177-83. PMID: 1735811.
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    311. Zaragoza RH, Szefler SJ, Bratton DL. Brief report: therapeutic manipulations in severe nocturnal asthma. A nonconventional approach in a severe high-risk asthmatic. J Asthma. 1992; 29(4):281-7. PMID: 1386072.
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    312. Glynn-Barnhart AM, Erzurum SC, Leff JA, Martin RJ, Cochran JE, Cott GR, Szefler SJ. Pharmacokinetics of low-dose methotrexate in adult asthmatics. Pharmacotherapy. 1992; 12(5):383-90. PMID: 1437699.
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    313. Kamada AK, Hill MR, Brenner AM, Szefler SJ. Effect of low-dose troleandomycin on theophylline clearance: implications for therapeutic drug monitoring. Pharmacotherapy. 1992; 12(2):98-102. PMID: 1570234.
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    314. Szefler SJ, Kamada AK, Hughes D, Brenner AM, Gelfand EW. Alternative treatments for asthma: assessing the need. J Asthma. 1992; 29(2):91-7. PMID: 1639739.
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    315. Alvarez J, Szefler SJ. Alternative therapy in severe asthma. J Asthma. 1992; 29(1):3-11. PMID: 1544882.
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    316. Corrigan CJ, Brown PH, Barnes NC, Szefler SJ, Tsai JJ, Frew AJ, Kay AB. Glucocorticoid resistance in chronic asthma. Glucocorticoid pharmacokinetics, glucocorticoid receptor characteristics, and inhibition of peripheral blood T cell proliferation by glucocorticoids in vitro. Am Rev Respir Dis. 1991 Nov; 144(5):1016-25. PMID: 1952426.
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    317. Greos LS, Vichyanond P, Bloedow DC, Irvin CG, Larsen GL, Szefler SJ, Hill MR. Methylprednisolone achieves greater concentrations in the lung than prednisolone. A pharmacokinetic analysis. Am Rev Respir Dis. 1991 Sep; 144(3 Pt 1):586-92. PMID: 1892299.
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    318. Glynn-Barnhart AM, Erzurum SC, Leff JA, Martin RJ, Cochran JE, Cott GR, Szefler SJ. Effect of low-dose methotrexate on the disposition of glucocorticoids and theophylline. J Allergy Clin Immunol. 1991 Aug; 88(2):180-6. PMID: 1880318.
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    319. Szefler SJ. Glucocorticoid therapy for asthma: clinical pharmacology. J Allergy Clin Immunol. 1991 Aug; 88(2):147-65. PMID: 1880315.
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    320. Nelson HS, Szefler SJ, Martin RJ. Regular inhaled beta-adrenergic agonists in the treatment of bronchial asthma: beneficial or detrimental? Am Rev Respir Dis. 1991 Aug; 144(2):249-50. PMID: 1677552.
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    321. Erzurum SC, Leff JA, Cochran JE, Ackerson LM, Szefler SJ, Martin RJ, Cott GR. Lack of benefit of methotrexate in severe, steroid-dependent asthma. A double-blind, placebo-controlled study. Ann Intern Med. 1991 Mar 01; 114(5):353-60. PMID: 1992876.
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    322. Martin RJ, Cicutto LC, Smith HR, Ballard RD, Szefler SJ. Airways inflammation in nocturnal asthma. Am Rev Respir Dis. 1991 Feb; 143(2):351-7. PMID: 1990952.
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    323. Szefler SJ, Ando R, Cicutto LC, Surs W, Hill MR, Martin RJ. Plasma histamine, epinephrine, cortisol, and leukocyte beta-adrenergic receptors in nocturnal asthma. Clin Pharmacol Ther. 1991 Jan; 49(1):59-68. PMID: 1846332.
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    324. Bender BG, Lerner JA, Ikle D, Comer C, Szefler S. Psychological change associated with theophylline treatment of asthmatic children: a 6-month study. Pediatr Pulmonol. 1991; 11(3):233-42. PMID: 1758745.
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    325. Hill MR, Szefler SJ, Ball BD, Bartoszek M, Brenner AM. Monitoring glucocorticoid therapy: a pharmacokinetic approach. Clin Pharmacol Ther. 1990 Oct; 48(4):390-8. PMID: 2225699.
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    326. Vichyanond P, Sladek WA, Sur S, Hill MR, Szefler SJ, Nelson HS. Efficacy of atropine methylnitrate alone and in combination with albuterol in children with asthma. Chest. 1990 Sep; 98(3):637-42. PMID: 2203617.
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    327. Ball BD, Hill MR, Brenner M, Sanks R, Szefler SJ. Effect of low-dose troleandomycin on glucocorticoid pharmacokinetics and airway hyperresponsiveness in severely asthmatic children. Ann Allergy. 1990 Jul; 65(1):37-45. PMID: 2195921.
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    328. Szefler SJ. Measuring the response to glucocorticoids. J Allergy Clin Immunol. 1990 Jun; 85(6):985-7. PMID: 2355157.
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    329. Vichyanond P, Irvin CG, Larsen GL, Szefler SJ, Hill MR. Penetration of corticosteroids into the lung: evidence for a difference between methylprednisolone and prednisolone. J Allergy Clin Immunol. 1989 Dec; 84(6 Pt 1):867-73. PMID: 2600321.
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    330. Kossoy AF, Hill M, Lin FL, Szefler SJ. Are theophylline "levels" a reliable indicator of compliance? J Allergy Clin Immunol. 1989 Jul; 84(1):60-5. PMID: 2754145.
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    331. Szefler SJ, Norton CE, Ball B, Gross JM, Aida Y, Pabst MJ. IFN-gamma and LPS overcome glucocorticoid inhibition of priming for superoxide release in human monocytes. Evidence that secretion of IL-1 and tumor necrosis factor-alpha is not essential for monocyte priming. J Immunol. 1989 Jun 01; 142(11):3985-92. PMID: 2541203.
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    332. Glynn-Barnhart A, Hill M, Szefler SJ. Sustained release theophylline preparations. Practical recommendations for prescribing and therapeutic drug monitoring. Drugs. 1988 Jun; 35(6):711-26. PMID: 3048977.
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    333. Hill M, Haltom JR, Szefler SJ. The consistency of theophylline absorption from a sustained-release formulation in asthmatic children. Pharmacotherapy. 1988; 8(5):277-83. PMID: 3255299.
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    334. Rogers RJ, Wiener MB, Hill MR, Szefler SJ. Theophylline absorption from two sustained-release products. Implications for therapeutic drug monitoring. Am Rev Respir Dis. 1987 Nov; 136(5):1168-73. PMID: 3674579.
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    335. Bartoszek M, Brenner AM, Szefler SJ. Prednisolone and methylprednisolone kinetics in children receiving anticonvulsant therapy. Clin Pharmacol Ther. 1987 Oct; 42(4):424-32. PMID: 3665340.
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    336. Weinberger M, Lindgren S, Bender B, Lerner JA, Szefler S. Effects of theophylline on learning and behavior: reason for concern or concern without reason? J Pediatr. 1987 Sep; 111(3):471-4. PMID: 3305851.
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    337. Szefler SJ, Edwards CK, Haslett C, Zahniser NR, Miller JA, Henson PM. Effects of cell isolation procedures and radioligand selection on the characterization of human leukocyte beta-adrenergic receptors. Biochem Pharmacol. 1987 May 15; 36(10):1589-97. PMID: 3036150.
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    338. Ebling WF, Rich SA, Szefler SJ, Jusko WJ. Troleandomycin effects on methylprednisolone and methylprednisone interconversion and disposition in the rabbit. Eur J Drug Metab Pharmacokinet. 1987 Jan-Mar; 12(1):50-7. PMID: 3497038.
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    339. Bartoszek M, Szefler SJ. Corticosteroid therapy in adolescent patients. J Adolesc Health Care. 1987 Jan; 8(1):84-91. PMID: 3546229.
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    340. Szefler SJ. Erratic absorption of theophylline from slow-release products in children. J Allergy Clin Immunol. 1986 Oct; 78(4 Pt 2):710-5. PMID: 3534052.
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    341. Ebling WF, Milsap RL, Szefler SJ, Jusko WJ. 6 alpha-Methylprednisolone and 6 alpha-methylprednisone plasma protein binding in humans and rabbits. J Pharm Sci. 1986 Aug; 75(8):760-3. PMID: 3772747.
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    342. Suez D, Szefler SJ. Excessive accumulation of mucus in children with asthma: a potential role for erythromycin? A case discussion. J Allergy Clin Immunol. 1986 Feb; 77(2):330-4. PMID: 3944384.
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    343. Vaughan LM, Weinberger MM, Milavetz G, Tillson S, Ellis E, Jenne J, Szefler SJ, Wiener MB, Conboy K, Shaughnessy T, et al. Multicentre evaluation of disposable visual measuring device to assay theophylline from capillary blood sample. Lancet. 1986 Jan 25; 1(8474):184-6. PMID: 2868208.
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    344. Szefler SJ, Ebling WF, Georgitis JW, Jusko WJ. Methylprednisolone versus prednisolone pharmacokinetics in relation to dose in adults. Eur J Clin Pharmacol. 1986; 30(3):323-9. PMID: 3732369.
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    345. Haltom JR, Szefler SJ. Theophylline absorption in young asthmatic children receiving sustained-release formulations. J Pediatr. 1985 Nov; 107(5):805-10. PMID: 4056986.
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    346. Szefler SJ. Theophylline and its fickle unpredictability of absorption. Ann Allergy. 1985 Oct; 55(4):580-3. PMID: 3901834.
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    347. Ebling WF, Szefler SJ, Jusko WJ. Methylprednisolone disposition in rabbits. Analysis, prodrug conversion, reversible metabolism, and comparison with man. Drug Metab Dispos. 1985 May-Jun; 13(3):296-304. PMID: 2861987.
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    348. Rogers RJ, Kalisker A, Wiener MB, Szefler SJ. Inconsistent absorption from a sustained-release theophylline preparation during continuous therapy in asthmatic children. J Pediatr. 1985 Mar; 106(3):496-501. PMID: 3973788.
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    349. Georgitis JW, Szefler SJ, Baswell B, Shen DD. Use of pharmacokinetic profile in evaluating patients with repeatedly low theophylline concentrations. Ann Allergy. 1984 Sep; 53(3):231-5. PMID: 6476482.
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    350. Szefler SJ, Rogers RJ, Strunk RC. Drug abuse and the asthmatic patient: a case report. J Allergy Clin Immunol. 1984 Aug; 74(2):201-4. PMID: 6747141.
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    351. Ebling WF, Szefler SJ, Jusko WJ. Analysis of cortisol, methylprednisolone, and methylprednisolone hemisuccinate. Absence of effects of troleandomycin on ester hydrolysis. J Chromatogr. 1984 Feb 10; 305(2):271-80. PMID: 6368578.
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    352. Szefler SJ. Inter- and intra-subject variability in theophylline pharmacokinetics. Br J Clin Pract Suppl. 1984; 35:10-6. PMID: 6433953.
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    353. Szefler SJ. Practical considerations in the safe and effective use of theophylline. Pediatr Clin North Am. 1983 Oct; 30(5):943-54. PMID: 6622082.
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    354. LaForce CF, Szefler SJ, Miller MF, Ebling W, Brenner M. Inhibition of methylprednisolone elimination in the presence of erythromycin therapy. J Allergy Clin Immunol. 1983 Jul; 72(1):34-9. PMID: 6602160.
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    355. Boekenoogen SJ, Szefler SJ, Jusko WJ. Prednisolone disposition and protein binding in oral contraceptive users. J Clin Endocrinol Metab. 1983 Apr; 56(4):702-9. PMID: 6833459.
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    356. Milsap RL, George DE, Szefler SJ, Murray KA, Lebenthal E, Jusko WJ. Effect of inflammatory bowel disease on absorption and disposition of prednisolone. Dig Dis Sci. 1983 Feb; 28(2):161-8. PMID: 6825536.
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    357. Szefler SJ. Drug excretion in human breast milk: potential effect on infant development. J Pediatr Gastroenterol Nutr. 1983; 2 Suppl 1:S120-6. PMID: 6644457.
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    358. Georgitis JW, Flesher KA, Szefler SJ. Bioavailability assessment of a liquid prednisone preparation. J Allergy Clin Immunol. 1982 Oct; 70(4):243-7. PMID: 7119300.
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    359. Szefler SJ, Pieroni DR, Gingell RL, Shen DD. Rapid elimination of quinidine in pediatric patients. Pediatrics. 1982 Sep; 70(3):370-5. PMID: 7110810.
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    360. Szefler SJ, Brenner M, Jusko WJ, Spector SL, Flesher KA, Ellis EF. Dose- and time-related effect of troleandomycin on methylprednisolone elimination. Clin Pharmacol Ther. 1982 Aug; 32(2):166-71. PMID: 6980076.
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    361. Szefler SJ, Ellis EF, Brenner M, Rose JQ, Spector SL, Yurchak AM, Andrews F, Jusko WJ. Steroid-specific and anticonvulsant interaction aspects of troleandomycin-steroid therapy. J Allergy Clin Immunol. 1982 May; 69(5):455-60. PMID: 6978898.
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    362. Zarowitz BJ, Wynn RJ, Buckwald S, Szefler SJ. High gentamicin trough concentrations in neonates of less than 28 weeks gestational age. Dev Pharmacol Ther. 1982; 5(1-2):68-75. PMID: 7151639.
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    363. Dederich RA, Szefler SJ, Green ER. Intrasubject variation in sustained-release theophylline absorption. J Allergy Clin Immunol. 1981 Jun; 67(6):465-71. PMID: 7346530.
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    364. Rocci ML, Szefler SJ, Acara M, Jusko WJ. Prednisolone metabolism and excretion in the isolated perfused rat kidney. Drug Metab Dispos. 1981 May-Jun; 9(3):177-82. PMID: 6113924.
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    365. Zarowitz BJ, Szefler SJ, Lasezkay GM. Effect of erythromycin base on theophylline kinetics. Clin Pharmacol Ther. 1981 May; 29(5):601-5. PMID: 7214790.
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    366. Lee TP, Szefler S, Ellis EF. Beta-adrenergic receptors of human polymorphonuclear leukocytes. Res Commun Chem Pathol Pharmacol. 1981 Mar; 31(3):453-62. PMID: 6265989.
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    367. Szefler SJ, Rose JQ, Ellis EF, Spector SL, Green AW, Jusko WJ. The effect of troleandomycin on methylprednisolone elimination. J Allergy Clin Immunol. 1980 Dec; 66(6):447-51. PMID: 6968763.
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    368. Szefler SJ, Wynn RJ, Clarke DF, Buckwald S, Shen D, Schentag JJ. Relationship of gentamicin serum concentrations to gestational age in preterm and term neonates. J Pediatr. 1980 Aug; 97(2):312-5. PMID: 7400909.
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    369. Szefler SJ, Acara M. Isoproterenol excretion and metabolism in the isolated perfused rat kidney. J Pharmacol Exp Ther. 1979 Aug; 210(2):295-300. PMID: 458636.
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    370. Szefler SJ, Koup JR, Giacoia GP. Paradoxical behavior of serum digoxin concentrations in an anuric neonate. J Pediatr. 1977 Sep; 91(3):487-9. PMID: 894426.
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    371. Jusko WJ, Szefler SJ, Goldfarb AL. Pharmacokinetic design of digoxin dosage regimens in relation to renal function. J Clin Pharmacol. 1974 Oct; 14(10):525-35. PMID: 4430731.
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    372. Szefler SJ, Jusko WJ. Decreased volume of distribution of digoxin in a patient with renal failure. Res Commun Chem Pathol Pharmacol. 1973 Nov; 6(3):1095-8. PMID: 4760884.
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