Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

Tim Chifong Lei

TitleAssociate Professor
InstitutionUniversity of Colorado Denver - Denver Campus
DepartmentCEDC-Electrical Engineering
Phone303/375-7585
    Other Positions
    TitleAssociate Professor
    InstitutionUniversity of Colorado Denver - Denver Campus
    DepartmentCEDC-Electrical Engineering


    Collapse Research 
    Collapse research activities and funding
    R41NS132700     (LEI, TIM CHIFONG)Sep 22, 2023 - Aug 31, 2025
    NIH
    Live spike sorting for multichannel and high-channel recordings
    Role: Principal Investigator
    K25DK095232     (LEI, TIM CHIFONG)Sep 20, 2012 - Feb 28, 2018
    NIH
    Imaging Transporter Protein Dynamics in Living Cells
    Role: Principal Investigator
    S10RR025447     (LEI, TIM C)Apr 1, 2009 - Sep 30, 2010
    NIH
    Coherent AntiStokes Raman Scattering Microscope
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. New EM, Hurd JA, Alarcon GA, Miller CS, Williams PA, Greene NT, Sergott CE, Li BZ, Lei TC, McCullagh EA. Hearing ability of prairie voles (Microtus ochrogaster). J Acoust Soc Am. 2024 01 01; 155(1):555-567. PMID: 38259128.
      View in: PubMed
    2. Harid V, Kim H, Li BZ, Lei T. A method for non-destructive microwave focusing for deep brain and tissue stimulation. PLoS One. 2023; 18(2):e0278765. PMID: 36758006.
      View in: PubMed
    3. Shen J, Xu Y, Xiao Z, Liu Y, Liu H, Wang F, Yan C, Wang L, Chen C, Wu Z, Liu Y, Mak PU, Vai MI, Pun SH, Lei TC, Zhang B. Double-Sided Sapphire Optrodes with Conductive Shielding Layers to Reduce Optogenetic Stimulation Artifacts. Micromachines (Basel). 2022 Oct 27; 13(11). PMID: 36363857.
      View in: PubMed
    4. Li BZ, Pun SH, Vai MI, Lei TC, Klug A. Predicting the Influence of Axon Myelination on Sound Localization Precision Using a Spiking Neural Network Model of Auditory Brainstem. Front Neurosci. 2022; 16:840983. PMID: 35360169.
      View in: PubMed
    5. Li BZ, Pun SH, Vai MI, Klug A, Lei TC. Axonal Conduction Delay Shapes the Precision of the Spatial Hearing in A Spiking Neural Network Model of Auditory Brainstem. Annu Int Conf IEEE Eng Med Biol Soc. 2021 11; 2021:4238-4241. PMID: 34892159.
      View in: PubMed
    6. Shen J, Xu Y, Xiao Z, Liu Y, Liu H, Wang F, Yao W, Yan Z, Zhang M, Wu Z, Liu Y, Pun SH, Lei TC, Vai MI, Mak PU, Chen C, Zhang B. Influence of the Surface Material and Illumination upon the Performance of a Microelectrode/Electrolyte Interface in Optogenetics. Micromachines (Basel). 2021 Aug 31; 12(9). PMID: 34577704.
      View in: PubMed
    7. Sun C, Yin Z, Li BZ, Du H, Tang K, Liu P, Hang Pun S, Lei TC, Li A. Oxytocin modulates neural processing of mitral/tufted cells in the olfactory bulb. Acta Physiol (Oxf). 2021 04; 231(4):e13626. PMID: 33580583.
      View in: PubMed
    8. Ly PT, Lucas A, Pun SH, Dondzillo A, Liu C, Klug A, Lei TC. Robotic stereotaxic system based on 3D skull reconstruction to improve surgical accuracy and speed. J Neurosci Methods. 2021 01 01; 347:108955. PMID: 32971134.
      View in: PubMed
    9. Zou J, Li W, Meng N, Jiang J, Wu C, Lei TC, Sroka R, Huang Z. Evaluation of lensed fibers used in photodynamic therapy (PDT). Photodiagnosis Photodyn Ther. 2020 Sep; 31:101924. PMID: 32682862.
      View in: PubMed
    10. Pang Y, Christenson J, Jiang F, Lei T, Rhoades R, Kern D, Thompson JA, Liu C. Automatic detection and quantification of hand movements toward development of an objective assessment of tremor and bradykinesia in Parkinson's disease. J Neurosci Methods. 2020 03 01; 333:108576. PMID: 31923452.
      View in: PubMed
    11. Wang PK, Pun SH, Chen CH, McCullagh EA, Klug A, Li A, Vai MI, Mak PU, Lei TC. Low-latency single channel real-time neural spike sorting system based on template matching. PLoS One. 2019; 14(11):e0225138. PMID: 31756211.
      View in: PubMed
    12. Mohammadi Z, Kincaid JM, Pun SH, Klug A, Liu C, Lei TC. Computationally inexpensive enhanced growing neural gas algorithm for real-time adaptive neural spike clustering. J Neural Eng. 2019 07 30; 16(5):056007. PMID: 31071700.
      View in: PubMed
    13. Li W, Li P, Fang Y, Lei TC, Dong K, Zou J, Gong W, Xie S, Huang Z. Quantitative assessment of skin swelling using optical coherence tomography. Photodiagnosis Photodyn Ther. 2019 Jun; 26:413-419. PMID: 31054333.
      View in: PubMed
    14. Musani AI, Veir JK, Huang Z, Lei T, Groshong S, Worley D. Photodynamic therapy via navigational bronchoscopy for peripheral lung cancer in dogs. Lasers Surg Med. 2018 07; 50(5):483-490. PMID: 29399826.
      View in: PubMed
    15. Chen CH, McCullagh EA, Pun SH, Mak PU, Vai MI, Mak PI, Klug A, Lei TC. An Integrated Circuit for Simultaneous Extracellular Electrophysiology Recording and Optogenetic Neural Manipulation. IEEE Trans Biomed Eng. 2017 03; 64(3):557-568. PMID: 28221990.
      View in: PubMed
    16. Zhang X, Liu N, Mak PU, Pun SH, Vai MI, Masihzadeh O, Kahook MY, Lei TC, Ammar DA. Three-Dimensional Segmentation and Quantitative Measurement of the Aqueous Outflow System of Intact Mouse Eyes Based on Spectral Two-Photon Microscopy Techniques. Invest Ophthalmol Vis Sci. 2016 06 01; 57(7):3159-67. PMID: 27309620.
      View in: PubMed
    17. Roth EJ, Mont-Eton ME, Gilbert B, Lei TC, Mays DC. Measurement of colloidal phenomena during flow through refractive index matched porous media. Rev Sci Instrum. 2015 Nov; 86(11):113103. PMID: 26628117.
      View in: PubMed
    18. Dondzillo A, Quinn KD, Cruickshank-Quinn CI, Reisdorph N, Lei TC, Klug A. A recording chamber for small volume slice electrophysiology. J Neurophysiol. 2015 Sep; 114(3):2053-64. PMID: 26203105.
      View in: PubMed
    19. Masihzadeh O, Lei TC, Domingue SR, Kahook MY, Bartels RA, Ammar DA. Third harmonic generation microscopy of a mouse retina. Mol Vis. 2015; 21:538-47. PMID: 25999681.
      View in: PubMed
    20. Chen CH, Pun SH, Mak PU, Vai MI, Klug A, Lei TC. Circuit models and experimental noise measurements of micropipette amplifiers for extracellular neural recordings from live animals. Biomed Res Int. 2014; 2014:135026. PMID: 25133158.
      View in: PubMed
    21. Lei TC, Masihzadeh O, Kahook MY, Ammar DA. Imaging the effects of prostaglandin analogues on cultured trabecular meshwork cells by coherent anti-stokes Raman scattering. Invest Ophthalmol Vis Sci. 2013 Sep 03; 54(9):5972-80. PMID: 23900606.
      View in: PubMed
    22. Ammar DA, Lei TC, Kahook MY, Masihzadeh O. Imaging the intact mouse cornea using coherent anti-stokes Raman scattering (CARS). Invest Ophthalmol Vis Sci. 2013 Aug 05; 54(8):5258-65. PMID: 23821187.
      View in: PubMed
    23. Al-Juboori SI, Dondzillo A, Stubblefield EA, Felsen G, Lei TC, Klug A. Light scattering properties vary across different regions of the adult mouse brain. PLoS One. 2013; 8(7):e67626. PMID: 23874433.
      View in: PubMed
    24. Masihzadeh O, Ammar DA, Kahook MY, Lei TC. Coherent anti-stokes Raman scattering (CARS) microscopy: a novel technique for imaging the retina. Invest Ophthalmol Vis Sci. 2013 May 01; 54(5):3094-101. PMID: 23580484.
      View in: PubMed
    25. Lei TC, Pendyala S, Scherrer L, Li B, Glazner GF, Huang Z. Optical profiles of cathode ray tube and liquid crystal display monitors: implication in cutaneous phototoxicity in photodynamic therapy. Appl Opt. 2013 Apr 20; 52(12):2711-7. PMID: 23669681.
      View in: PubMed
    26. Masihzadeh O, Ammar DA, Kahook MY, Gibson EA, Lei TC. Direct trabecular meshwork imaging in porcine eyes through multiphoton gonioscopy. J Biomed Opt. 2013 Mar; 18(3):036009. PMID: 23515864.
      View in: PubMed
    27. Dobrinskikh E, Lanzano L, Rachelson J, Cranston D, Moldovan R, Lei T, Gratton E, Doctor RB. Shank2 contributes to the apical retention and intracellular redistribution of NaPiIIa in OK cells. Am J Physiol Cell Physiol. 2013 Mar; 304(6):C561-73. PMID: 23325414.
      View in: PubMed
    28. Masihzadeh O, Lei TC, Ammar DA, Kahook MY, Gibson EA. A multiphoton microscope platform for imaging the mouse eye. Mol Vis. 2012; 18:1840-8. PMID: 22815637.
      View in: PubMed
    29. Lei TC, Glazner GF, Duffy M, Scherrer L, Pendyala S, Li B, Wang X, Wang H, Huang Z. Optical properties of hematoporphyrin monomethyl ether (HMME), a PDT photosensitizer. Photodiagnosis Photodyn Ther. 2012 Sep; 9(3):232-42. PMID: 22959803.
      View in: PubMed
    30. Lei TC, Ammar DA, Masihzadeh O, Gibson EA, Kahook MY. Label-free imaging of trabecular meshwork cells using Coherent Anti-Stokes Raman Scattering (CARS) microscopy. Mol Vis. 2011; 17:2628-33. PMID: 22025898.
      View in: PubMed
    31. Mays DC, Cannon OT, Kanold AW, Harris KJ, Lei TC, Gilbert B. Static light scattering resolves colloid structure in index-matched porous media. J Colloid Interface Sci. 2011 Nov 01; 363(1):418-24. PMID: 21839461.
      View in: PubMed
    32. Blaine J, Lanzano L, Giral H, Caldas Y, Levi M, Gratton E, Moldovan R, Lei T. Dynamic imaging of the sodium phosphate cotransporters. Adv Chronic Kidney Dis. 2011 Mar; 18(2):145-50. PMID: 21406299.
      View in: PubMed
    33. Masihzadeh O, Ammar DA, Lei TC, Gibson EA, Kahook MY. Real-time measurements of nicotinamide adenine dinucleotide in live human trabecular meshwork cells: effects of acute oxidative stress. Exp Eye Res. 2011 Sep; 93(3):316-20. PMID: 21354135.
      View in: PubMed
    34. Ammar DA, Lei TC, Masihzadeh O, Gibson EA, Kahook MY. Trans-scleral imaging of the human trabecular meshwork by two-photon microscopy. Mol Vis. 2011 Feb 24; 17:583-90. PMID: 21386924.
      View in: PubMed
    35. Gibson EA, Masihzadeh O, Lei TC, Ammar DA, Kahook MY. Multiphoton microscopy for ophthalmic imaging. J Ophthalmol. 2011; 2011:870879. PMID: 21274261.
      View in: PubMed
    36. Ammar DA, Lei TC, Gibson EA, Kahook MY. Two-photon imaging of the trabecular meshwork. Mol Vis. 2010 May 29; 16:935-44. PMID: 20596237.
      View in: PubMed
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