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Timothy DeGrado

TitleProfessor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-RAD General Operations

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Bansal A, Pandey MK, Yamada S, Goyal R, Schmit NR, Jeon R, Nesbitt JJ, Witt TA, Singh RD, Gunderson TM, Boroumand S, Li M, Crespo-Diaz RJ, Hillestad ML, Terzic A, Behfar A, DeGrado TR. [89Zr]Zr-DBN labeled cardiopoietic stem cells proficient for heart failure. Nucl Med Biol. 2020 Nov - Dec; 90-91:23-30. PMID: 32957056.
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    2. Joaqui-Joaqui MA, Pandey MK, Bansal A, Raju MVR, Armstrong-Pavlik F, Dundar A, Wong HL, DeGrado TR, Pierre VC. Catechol-Based Functionalizable Ligands for Gallium-68 Positron Emission Tomography Imaging. Inorg Chem. 2020 Sep 08; 59(17):12025-12038. PMID: 32820888.
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    3. Pandey MK, DeGrado TR. Cyclotron Production of PET Radiometals in Liquid Targets: Aspects and Prospects. Curr Radiopharm. 2020 Aug 20. PMID: 32867656.
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    4. Nicolas CT, Kaiser RA, Hickey RD, Allen KL, Du Z, VanLith CJ, Guthman RM, Amiot B, Suksanpaisan L, Han B, Francipane MG, Cheikhi A, Jiang H, Bansal A, Pandey MK, Garg I, Lowe V, Bhagwate A, O'Brien D, Kocher JA, DeGrado TR, Nyberg SL, Lagasse E, Lillegard JB. Ex Vivo Cell Therapy by Ectopic Hepatocyte Transplantation Treats the Porcine Tyrosinemia Model of Acute Liver Failure. Mol Ther Methods Clin Dev. 2020 Sep 11; 18:738-750. PMID: 32913881.
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    5. Dasgupta D, Nakao Y, Mauer AS, Thompson JM, Sehrawat TS, Liao CY, Krishnan A, Lucien F, Guo Q, Liu M, Xue F, Fukushima M, Katsumi T, Bansal A, Pandey MK, Maiers JL, DeGrado T, Ibrahim SH, Revzin A, Pavelko KD, Barry MA, Kaufman RJ, Malhi H. IRE1A Stimulates Hepatocyte-Derived Extracellular Vesicles That Promote Inflammation in Mice With Steatohepatitis. Gastroenterology. 2020 Oct; 159(4):1487-1503.e17. PMID: 32574624.
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    6. Pandey MK, Jacobson MS, Groth EK, Tran NG, Lowe VJ, DeGrado TR. Radiation induced oxidation of [18F]fluorothia fatty acids under cGMP manufacturing conditions. Nucl Med Biol. 2020 Jan - Feb; 80-81:13-23. PMID: 31759313.
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    7. Zhang L, Suksanpaisan L, Jiang H, DeGrado TR, Russell SJ, Zhao M, Peng KW. Dual-Isotope SPECT Imaging with NIS Reporter Gene and Duramycin to Visualize Tumor Susceptibility to Oncolytic Virus Infection. Mol Ther Oncolytics. 2019 Dec 20; 15:178-185. PMID: 31890867.
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    8. Pandey MK, Byrne JF, Schlasner KN, Schmit NR, DeGrado TR. Cyclotron production of 68Ga in a liquid target: Effects of solution composition and irradiation parameters. Nucl Med Biol. 2019 Jul - Aug; 74-75:49-55. PMID: 31085059.
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    9. Vandergaast R, Khongwichit S, Jiang H, DeGrado TR, Peng KW, Smith DR, Russell SJ, Suksanpaisan L. Enhanced noninvasive imaging of oncology models using the NIS reporter gene and bioluminescence imaging. Cancer Gene Ther. 2020 04; 27(3-4):179-188. PMID: 30674994.
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    10. Landry GM, Furrow E, Holmes HL, Hirata T, Kato A, Williams P, Strohmaier K, Gallo CJR, Chang M, Pandey MK, Jiang H, Bansal A, Franz MC, Montalbetti N, Alexander MP, Cabrero P, Dow JAT, DeGrado TR, Romero MF. Cloning, function, and localization of human, canine, and Drosophila ZIP10 (SLC39A10), a Zn2+ transporter. Am J Physiol Renal Physiol. 2019 02 01; 316(2):F263-F273. PMID: 30520657.
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    11. DeGrado TR, Pandey MK, Belanger AP, Basuli F, Bansal A, Wang S. Noninvasive evaluation of fat-carbohydrate metabolic switching in heart and contracting skeletal muscle. Am J Physiol Endocrinol Metab. 2019 02 01; 316(2):E251-E259. PMID: 30512988.
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    12. Brunton B, Suksanpaisan L, Li H, Liu Q, Yu Y, Vrieze A, Zhang L, Jenks N, Jiang H, DeGrado TR, Zhao C, Russell SJ, Peng KW. New transgenic NIS reporter rats for longitudinal tracking of fibrogenesis by high-resolution imaging. Sci Rep. 2018 09 21; 8(1):14209. PMID: 30242176.
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    13. Jiang H, DeGrado TR. [18F]Tetrafluoroborate ([18F]TFB) and its analogs for PET imaging of the sodium/iodide symporter. Theranostics. 2018; 8(14):3918-3931. PMID: 30083270.
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    14. Franz MC, Pujol-Giménez J, Montalbetti N, Fernandez-Tenorio M, DeGrado TR, Niggli E, Romero MF, Hediger MA. Reassessment of the Transport Mechanism of the Human Zinc Transporter SLC39A2. Biochemistry. 2018 07 03; 57(26):3976-3986. PMID: 29791142.
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    15. Nicolas CT, Hickey RD, Allen KL, Du Z, Guthman RM, Kaiser RA, Amiot B, Bansal A, Pandey MK, Suksanpaisan L, DeGrado TR, Nyberg SL, Lillegard JB. Hepatocyte spheroids as an alternative to single cells for transplantation after ex vivo gene therapy in mice and pig models. Surgery. 2018 09; 164(3):473-481. PMID: 29884476.
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    16. Jiang H, Bansal A, Goyal R, Peng KW, Russell SJ, DeGrado TR. Synthesis and evaluation of 18F-hexafluorophosphate as a novel PET probe for imaging of sodium/iodide symporter in a murine C6-glioma tumor model. Bioorg Med Chem. 2018 01 01; 26(1):225-231. PMID: 29198608.
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    17. Jiang H, Schmit NR, Koenen AR, Bansal A, Pandey MK, Glynn RB, Kemp BJ, Delaney KL, Dispenzieri A, Bakkum-Gamez JN, Peng KW, Russell SJ, Gunderson TM, Lowe VJ, DeGrado TR. Safety, pharmacokinetics, metabolism and radiation dosimetry of 18F-tetrafluoroborate (18F-TFB) in healthy human subjects. EJNMMI Res. 2017 Oct 27; 7(1):90. PMID: 29080017.
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    18. DeGrado TR, Kemp BJ, Pandey MK, Jiang H, Gunderson TM, Linscheid LR, Woodwick AR, McConnell DM, Fletcher JG, Johnson GB, Petersen RC, Knopman DS, Lowe VJ. First PET Imaging Studies With 63Zn-Zinc Citrate in Healthy Human Participants and Patients With Alzheimer Disease. Mol Imaging. 2016; 15. PMID: 27941122.
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    19. Hickey RD, Mao SA, Glorioso J, Elgilani F, Amiot B, Chen H, Rinaldo P, Marler R, Jiang H, DeGrado TR, Suksanpaisan L, O'Connor MK, Freeman BL, Ibrahim SH, Peng KW, Harding CO, Ho CS, Grompe M, Ikeda Y, Lillegard JB, Russell SJ, Nyberg SL. Curative ex vivo liver-directed gene therapy in a pig model of hereditary tyrosinemia type 1. Sci Transl Med. 2016 07 27; 8(349):349ra99. PMID: 27464750.
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    20. Jiang H, Bansal A, Pandey MK, Peng KW, Suksanpaisan L, Russell SJ, DeGrado TR. Synthesis of 18F-Tetrafluoroborate via Radiofluorination of Boron Trifluoride and Evaluation in a Murine C6-Glioma Tumor Model. J Nucl Med. 2016 09; 57(9):1454-9. PMID: 27103021.
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    21. Mather KJ, DeGrado TR. Imaging of myocardial fatty acid oxidation. Biochim Biophys Acta. 2016 10; 1861(10):1535-43. PMID: 26923433.
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    22. Pandey MK, DeGrado TR. Glycogen Synthase Kinase-3 (GSK-3)-Targeted Therapy and Imaging. Theranostics. 2016; 6(4):571-93. PMID: 26941849.
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    23. Mather KJ, Hutchins GD, Perry K, Territo W, Chisholm R, Acton A, Glick-Wilson B, Considine RV, Moberly S, DeGrado TR. Assessment of myocardial metabolic flexibility and work efficiency in human type 2 diabetes using 16-[18F]fluoro-4-thiapalmitate, a novel PET fatty acid tracer. Am J Physiol Endocrinol Metab. 2016 Mar 15; 310(6):E452-60. PMID: 26732686.
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    24. Yang B, Brahmbhatt A, Nieves Torres E, Thielen B, McCall DL, Engel S, Bansal A, Pandey MK, Dietz AB, Leof EB, DeGrado TR, Mukhopadhyay D, Misra S. Tracking and Therapeutic Value of Human Adipose Tissue-derived Mesenchymal Stem Cell Transplantation in Reducing Venous Neointimal Hyperplasia Associated with Arteriovenous Fistula. Radiology. 2016 May; 279(2):513-22. PMID: 26583911.
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    25. Jiang H, DiMagno SG, DeGrado TR. Production and Transport of Gaseous 18F-Synthons: 18F-Acyl Fluorides. J Fluor Chem. 2015 Dec; 180:181-185. PMID: 27003949.
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    26. Pandey MK, Bansal A, Engelbrecht HP, Byrne JF, Packard AB, DeGrado TR. Improved production and processing of 8?Zr using a solution target. Nucl Med Biol. 2016 Jan; 43(1):97-100. PMID: 26471714.
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    27. Bansal A, Pandey MK, Demirhan YE, Nesbitt JJ, Crespo-Diaz RJ, Terzic A, Behfar A, DeGrado TR. Novel (89)Zr cell labeling approach for PET-based cell trafficking studies. EJNMMI Res. 2015; 5:19. PMID: 25918673.
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    28. Domingo-Musibay E, Allen C, Kurokawa C, Hardcastle JJ, Aderca I, Msaouel P, Bansal A, Jiang H, DeGrado TR, Galanis E. Measles Edmonston vaccine strain derivatives have potent oncolytic activity against osteosarcoma. Cancer Gene Ther. 2014 Nov; 21(11):483-90. PMID: 25394505.
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    29. DeGrado TR, Pandey MK, Byrne JF, Engelbrecht HP, Jiang H, Packard AB, Thomas KA, Jacobson MS, Curran GL, Lowe VJ. Preparation and preliminary evaluation of 63Zn-zinc citrate as a novel PET imaging biomarker for zinc. J Nucl Med. 2014 Aug; 55(8):1348-54. PMID: 25047329.
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    30. Pandey MK, DeGrado TR, Qian K, Jacobson MS, Hagen CE, Duclos RI, Gatley SJ. Synthesis and preliminary evaluation of N-(16-18F-fluorohexadecanoyl)ethanolamine (18F-FHEA) as a PET probe of N-acylethanolamine metabolism in mouse brain. ACS Chem Neurosci. 2014 Sep 17; 5(9):793-802. PMID: 25003845.
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    31. Pandey MK, Byrne JF, Jiang H, Packard AB, DeGrado TR. Cyclotron production of (68)Ga via the (68)Zn(p,n)(68)Ga reaction in aqueous solution. Am J Nucl Med Mol Imaging. 2014; 4(4):303-10. PMID: 24982816.
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    32. Pandey MK, Engelbrecht HP, Byrne JP, Packard AB, DeGrado TR. Production of 89Zr via the 89Y(p,n)89Zr reaction in aqueous solution: effect of solution composition on in-target chemistry. Nucl Med Biol. 2014 Apr; 41(4):309-16. PMID: 24607433.
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    33. Pandey MK, Belanger AP, Wang S, DeGrado TR. Structure dependence of long-chain [18F]fluorothia fatty acids as myocardial fatty acid oxidation probes. J Med Chem. 2012 Dec 13; 55(23):10674-84. PMID: 23153307.
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    34. Bansal A, Harris RA, DeGrado TR. Choline phosphorylation and regulation of transcription of choline kinase a in hypoxia. J Lipid Res. 2012 Jan; 53(1):149-57. PMID: 22025560.
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    35. Belanger AP, Pandey MK, DeGrado TR. Microwave-assisted radiosynthesis of [18F]fluorinated fatty acid analogs. Nucl Med Biol. 2011 Apr; 38(3):435-41. PMID: 21492792.
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    36. Beauregard JM, Williams SG, Degrado TR, Roselt P, Hicks RJ. Pilot comparison of F-fluorocholine and F-fluorodeoxyglucose PET/CT with conventional imaging in prostate cancer. J Med Imaging Radiat Oncol. 2010 Aug; 54(4):325-32. PMID: 20718912.
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    37. DeGrado TR, Bhattacharyya F, Pandey MK, Belanger AP, Wang S. Synthesis and preliminary evaluation of 18-(18)F-fluoro-4-thia-oleate as a PET probe of fatty acid oxidation. J Nucl Med. 2010 Aug; 51(8):1310-7. PMID: 20660391.
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    38. Belanger AP, Byrne JF, Paolino JM, DeGrado TR. Use of pressure-hold test for sterilizing filter membrane integrity in radiopharmaceutical manufacturing. Nucl Med Biol. 2009 Nov; 36(8):955-9. PMID: 19875052.
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    39. Kwee SA, DeGrado T. Prostate biopsy guided by 18F-fluorocholine PET in men with persistently elevated PSA levels. Eur J Nucl Med Mol Imaging. 2008 Aug; 35(8):1567-9; author reply 1570. PMID: 18521597.
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    40. Bhattacharyya S, Wang S, Reinecke D, Kiser W, Kruger RA, DeGrado TR. Synthesis and evaluation of near-infrared (NIR) dye-herceptin conjugates as photoacoustic computed tomography (PCT) probes for HER2 expression in breast cancer. Bioconjug Chem. 2008 Jun; 19(6):1186-93. PMID: 18505279.
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    41. Bansal A, Shuyan W, Hara T, Harris RA, Degrado TR. Biodisposition and metabolism of [(18)F]fluorocholine in 9L glioma cells and 9L glioma-bearing fisher rats. Eur J Nucl Med Mol Imaging. 2008 Jun; 35(6):1192-203. PMID: 18264706.
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    42. Kwee SA, DeGrado TR, Talbot JN, Gutman F, Coel MN. Cancer imaging with fluorine-18-labeled choline derivatives. Semin Nucl Med. 2007 Nov; 37(6):420-8. PMID: 17920349.
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    43. DeGrado TR, Kwee SA, Coel MN, Coleman RE. The impact of urinary excretion of (18)F-labeled choline analogs. J Nucl Med. 2007 Jul; 48(7):1225. PMID: 17607041.
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    44. Zheng QH, Gao M, Mock BH, Wang S, Hara T, Nazih R, Miller MA, Receveur TJ, Lopshire JC, Groh WJ, Zipes DP, Hutchins GD, DeGrado TR. Synthesis and biodistribution of new radiolabeled high-affinity choline transporter inhibitors [11C]hemicholinium-3 and [18F]hemicholinium-3. Bioorg Med Chem Lett. 2007 Apr 15; 17(8):2220-4. PMID: 17303422.
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    45. Gao M, Miller MA, DeGrado TR, Mock BH, Lopshire JC, Rosenberger JG, Dusa C, Das MK, Groh WJ, Zipes DP, Hutchins GD, Zheng QH. Evaluation of [11C]hemicholinium-15 and [18F]hemicholinium-15 as new potential PET tracers for the high-affinity choline uptake system in the heart. Bioorg Med Chem. 2007 Feb 01; 15(3):1289-97. PMID: 17116396.
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    46. Hara T, Bansal A, DeGrado TR. Effect of hypoxia on the uptake of [methyl-3H]choline, [1-14C] acetate and [18F]FDG in cultured prostate cancer cells. Nucl Med Biol. 2006 Nov; 33(8):977-84. PMID: 17127170.
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    47. Hara T, Bansal A, DeGrado TR. Choline transporter as a novel target for molecular imaging of cancer. Mol Imaging. 2006 Oct-Dec; 5(4):498-509. PMID: 17150162.
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    48. Shanmugam R, Jayaprakasan V, Gokmen-Polar Y, Kelich S, Miller KD, Yip-Schneider M, Cheng L, Bhat-Nakshatri P, Sledge GW, Nakshatri H, Zheng QH, Miller MA, DeGrado T, Hutchins GD, Sweeney CJ. Restoring chemotherapy and hormone therapy sensitivity by parthenolide in a xenograft hormone refractory prostate cancer model. Prostate. 2006 Oct 01; 66(14):1498-511. PMID: 16921510.
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    49. DeGrado TR, Kitapci MT, Wang S, Ying J, Lopaschuk GD. Validation of 18F-fluoro-4-thia-palmitate as a PET probe for myocardial fatty acid oxidation: effects of hypoxia and composition of exogenous fatty acids. J Nucl Med. 2006 Jan; 47(1):173-81. PMID: 16391202.
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    50. Nazih R, Blauser JP, Mock BH, Degrado TR. A facile synthesis of [(11)C]acetylene. Appl Radiat Isot. 2005 Sep; 63(3):305-9. PMID: 15990324.
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    51. Hughes GC, Biswas SS, Yin B, Coleman RE, DeGrado TR, Landolfo CK, Lowe JE, Annex BH, Landolfo KP. Therapeutic angiogenesis in chronically ischemic porcine myocardium: comparative effects of bFGF and VEGF. Ann Thorac Surg. 2004 Mar; 77(3):812-8. PMID: 14992878.
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    52. Hughes GC, Baklanov DV, Biswas SS, Pippen AM, DeGrado TR, Coleman RE, Landolfo CK, Lowe JE, Annex BH, Landolfo KP. Regional cardiac sympathetic innervation early and late after transmyocardial laser revascularization. J Card Surg. 2004 Jan-Feb; 19(1):21-7. PMID: 15108785.
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    53. Zheng QH, Fei X, DeGrado TR, Wang JQ, Stone KL, Martinez TD, Gay DJ, Baity WL, Mock BH, Glick-Wilson BE, Sullivan ML, Miller KD, Sledge GW, Hutchins GD. Synthesis, biodistribution and micro-PET imaging of a potential cancer biomarker carbon-11 labeled MMP inhibitor (2R)-2-[[4-(6-fluorohex-1-ynyl)phenyl]sulfonylamino]-3-methylbutyric acid [11C]methyl ester. Nucl Med Biol. 2003 Oct; 30(7):753-60. PMID: 14499334.
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    54. Mathew RJ, Wilson WH, Turkington TG, Hawk TC, Coleman RE, DeGrado TR, Provenzale J. Time course of tetrahydrocannabinol-induced changes in regional cerebral blood flow measured with positron emission tomography. Psychiatry Res. 2002 Dec 30; 116(3):173-85. PMID: 12477601.
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    55. Price DT, Coleman RE, Liao RP, Robertson CN, Polascik TJ, DeGrado TR. Comparison of [18 F]fluorocholine and [18 F]fluorodeoxyglucose for positron emission tomography of androgen dependent and androgen independent prostate cancer. J Urol. 2002 Jul; 168(1):273-80. PMID: 12050555.
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    56. Hughes GC, Biswas SS, Yin B, Baklanov DV, Annex BH, Coleman RE, DeGrado TR, Landolfo CK, Landolfo KP, Lowe JE. A comparison of mechanical and laser transmyocardial revascularization for induction of angiogenesis and arteriogenesis in chronically ischemic myocardium. J Am Coll Cardiol. 2002 Apr 03; 39(7):1220-8. PMID: 11923050.
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    57. Berry CR, DeGrado TR, Nutter F, Garg PK, Breitschwerdt EB, Spaulding K, Concannon KD, Zalutsky MR, Coleman RE. Imaging of pheochromocytoma in 2 dogs using p-[18F] fluorobenzylguanidine. Vet Radiol Ultrasound. 2002 Mar-Apr; 43(2):183-6. PMID: 11954815.
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    58. DeGrado TR, Reiman RE, Price DT, Wang S, Coleman RE. Pharmacokinetics and radiation dosimetry of 18F-fluorocholine. J Nucl Med. 2002 Jan; 43(1):92-6. PMID: 11801711.
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    59. DeGrado TR, Baldwin SW, Wang S, Orr MD, Liao RP, Friedman HS, Reiman R, Price DT, Coleman RE. Synthesis and evaluation of (18)F-labeled choline analogs as oncologic PET tracers. J Nucl Med. 2001 Dec; 42(12):1805-14. PMID: 11752077.
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    60. Hughes GC, Landolfo CK, Yin B, DeGrado TR, Coleman RE, Landolfo KP, Lowe JE. Is chronically dysfunctional yet viable myocardium distal to a severe coronary stenosis hypoperfused? Ann Thorac Surg. 2001 Jul; 72(1):163-8. PMID: 11465172.
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    61. Wallhaus TR, Taylor M, DeGrado TR, Russell DC, Stanko P, Nickles RJ, Stone CK. Myocardial free fatty acid and glucose use after carvedilol treatment in patients with congestive heart failure. Circulation. 2001 May 22; 103(20):2441-6. PMID: 11369683.
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    62. DeGrado TR, Coleman RE, Wang S, Baldwin SW, Orr MD, Robertson CN, Polascik TJ, Price DT. Synthesis and evaluation of 18F-labeled choline as an oncologic tracer for positron emission tomography: initial findings in prostate cancer. Cancer Res. 2001 Jan 01; 61(1):110-7. PMID: 11196147.
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    63. Taylor M, Wallhaus TR, Degrado TR, Russell DC, Stanko P, Nickles RJ, Stone CK. An evaluation of myocardial fatty acid and glucose uptake using PET with [18F]fluoro-6-thia-heptadecanoic acid and [18F]FDG in Patients with Congestive Heart Failure. J Nucl Med. 2001 Jan; 42(1):55-62. PMID: 11197981.
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    64. DeGrado TR, Bergmann SR, Ng CK, Raffel DM. Tracer kinetic modeling in nuclear cardiology. J Nucl Cardiol. 2000 Nov-Dec; 7(6):686-700. PMID: 11144484.
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    65. DeGrado TR, Wang S, Rockey DC. Preliminary evaluation of 15-[18F]fluoro-3-oxa-pentadecanoate as a PET tracer of hepatic fatty acid oxidation. J Nucl Med. 2000 Oct; 41(10):1727-36. PMID: 11038005.
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    66. Hughes GC, Kypson AP, Annex BH, Yin B, St Louis JD, Biswas SS, Coleman RE, DeGrado TR, Donovan CL, Landolfo KP, Lowe JE. Induction of angiogenesis after TMR: a comparison of holmium: YAG, CO2, and excimer lasers. Ann Thorac Surg. 2000 Aug; 70(2):504-9. PMID: 10969671.
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    67. St Louis JD, Hughes GC, Kypson AP, DeGrado TR, Donovan CL, Coleman RE, Yin B, Steenbergen C, Landolfo KP, Lowe JE. An experimental model of chronic myocardial hibernation. Ann Thorac Surg. 2000 May; 69(5):1351-7. PMID: 10881804.
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    68. DeGrado TR, Wang S, Holden JE, Nickles RJ, Taylor M, Stone CK. Synthesis and preliminary evaluation of (18)F-labeled 4-thia palmitate as a PET tracer of myocardial fatty acid oxidation. Nucl Med Biol. 2000 Apr; 27(3):221-31. PMID: 10832078.
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    69. Mathew RJ, Wilson WH, Chiu NY, Turkington TG, Degrado TR, Coleman RE. Regional cerebral blood flow and depersonalization after tetrahydrocannabinol administration. Acta Psychiatr Scand. 1999 Jul; 100(1):67-75. PMID: 10442442.
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    70. Hughes GC, Kypson AP, St Louis JD, Annex BH, Coleman RE, DeGrado TR, Donovan CL, Lowe JE, Landolfo KP. Improved perfusion and contractile reserve after transmyocardial laser revascularization in a model of hibernating myocardium. Ann Thorac Surg. 1999 Jun; 67(6):1714-20. PMID: 10391280.
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    71. Hughes GC, Lowe JE, Kypson AP, St Louis JD, Pippen AM, Peters KG, Coleman RE, DeGrado TR, Donovan CL, Annex BH, Landolfo KP. Neovascularization after transmyocardial laser revascularization in a model of chronic ischemia. Ann Thorac Surg. 1998 Dec; 66(6):2029-36. PMID: 9930489.
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    72. Vaidyanathan G, Zalutsky MR, DeGrado TR. Iodopyridine-for-iodobenzene substitution for use with low molecular weight radiopharmaceuticals: application to m-iodobenzylguanidine. Bioconjug Chem. 1998 Nov-Dec; 9(6):758-64. PMID: 9815170.
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    73. Renstrom B, Rommelfanger S, Stone CK, DeGrado TR, Carlson KJ, Scarbrough E, Nickles RJ, Liedtke AJ, Holden JE. Comparison of fatty acid tracers FTHA and BMIPP during myocardial ischemia and hypoxia. J Nucl Med. 1998 Oct; 39(10):1684-9. PMID: 9776269.
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    74. Stone CK, Pooley RA, DeGrado TR, Renstrom B, Nickles RJ, Nellis SH, Liedtke AJ, Holden JE. Myocardial uptake of the fatty acid analog 14-fluorine-18-fluoro-6-thia-heptadecanoic acid in comparison to beta-oxidation rates by tritiated palmitate. J Nucl Med. 1998 Oct; 39(10):1690-6. PMID: 9776270.
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    75. Vallée JP, Sostman HD, MacFall JR, DeGrado TR, Zhang J, Sebbag L, Cobb FR, Wheeler T, Hedlund LW, Turkington TG, Spritzer CE, Coleman RE. Quantification of myocardial perfusion by MRI after coronary occlusion. Magn Reson Med. 1998 Aug; 40(2):287-97. PMID: 9702711.
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    76. DeGrado TR, Wang S. Transcapillary transport of metaiodobenzylguanidine (MIBG) in isolated rat heart. Nucl Med Biol. 1998 Jul; 25(5):455-65. PMID: 9720663.
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    77. DeGrado TR, Zalutsky MR, Coleman RE, Vaidyanathan G. Effects of specific activity on meta-[(131)I]iodobenzylguanidine kinetics in isolated rat heart. Nucl Med Biol. 1998 Jan; 25(1):59-64. PMID: 9466363.
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    78. Nguyen NT, DeGrado TR, Chakraborty P, Wieland DM, Schwaiger M. Myocardial kinetics of carbon-11-epinephrine in the isolated working rat heart. J Nucl Med. 1997 May; 38(5):780-5. PMID: 9170446.
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    79. Mathew RJ, Wilson WH, Coleman RE, Turkington TG, DeGrado TR. Marijuana intoxication and brain activation in marijuana smokers. Life Sci. 1997; 60(23):2075-89. PMID: 9180362.
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    80. Berry CR, Garg PK, Zalutsky MR, Coleman RE, DeGrado TR. Uptake and retention kinetics of para-fluorine-18-fluorobenzylguanidine in isolated rat heart. J Nucl Med. 1996 Dec; 37(12):2011-6. PMID: 8970525.
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    81. DeGrado TR, Hanson MW, Turkington TG, Delong DM, Brezinski DA, Vallée JP, Hedlund LW, Zhang J, Cobb F, Sullivan MJ, Coleman RE. Estimation of myocardial blood flow for longitudinal studies with 13N-labeled ammonia and positron emission tomography. J Nucl Cardiol. 1996 Nov-Dec; 3(6 Pt 1):494-507. PMID: 8989674.
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    82. Madden DJ, Turkington TG, Coleman RE, Provenzale JM, DeGrado TR, Hoffman JM. Adult age differences in regional cerebral blood flow during visual world identification: evidence from H215O PET. Neuroimage. 1996 Apr; 3(2):127-42. PMID: 9345484.
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    83. Berry CR, Garg PK, DeGrado TR, Hellyer P, Weber W, Garg S, Hansen B, Zalutsky MR, Coleman RE. Para-[18F]fluorobenzylguanidine kinetics in a canine coronary artery occlusion model. J Nucl Cardiol. 1996 Mar-Apr; 3(2):119-29. PMID: 8799237.
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    84. Degrado TR, Zalutsky MR, Vaidyanathan G. Uptake mechanisms of meta-[123I]iodobenzylguanidine in isolated rat heart. Nucl Med Biol. 1995 Jan; 22(1):1-12. PMID: 7735158.
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    85. DeGrado TR, Turkington TG, Williams JJ, Stearns CW, Hoffman JM, Coleman RE. Performance characteristics of a whole-body PET scanner. J Nucl Med. 1994 Aug; 35(8):1398-406. PMID: 8046501.
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    86. Melon PG, Nguyen N, DeGrado TR, Mangner TJ, Wieland DM, Schwaiger M. Imaging of cardiac neuronal function after cocaine exposure using carbon-11 hydroxyephedrine and positron emission tomography. J Am Coll Cardiol. 1994 Jun; 23(7):1693-9. PMID: 8195534.
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    87. Sun D, Nguyen N, DeGrado TR, Schwaiger M, Brosius FC. Ischemia induces translocation of the insulin-responsive glucose transporter GLUT4 to the plasma membrane of cardiac myocytes. Circulation. 1994 Feb; 89(2):793-8. PMID: 8313568.
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    88. DeGrado TR, Mulholland GK, Wieland DM, Schwaiger M. Evaluation of (-)[18F]fluoroethoxybenzovesamicol as a new PET tracer of cholinergic neurons of the heart. Nucl Med Biol. 1994 Feb; 21(2):189-95. PMID: 9234282.
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    89. Ebert A, Herzog H, Stöcklin GL, Henrich MM, DeGrado TR, Coenen HH, Feinendegen LE. Kinetics of 14(R,S)-fluorine-18-fluoro-6-thia-heptadecanoic acid in normal human hearts at rest, during exercise and after dipyridamole injection. J Nucl Med. 1994 Jan; 35(1):51-6. PMID: 8271060.
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    90. Allman KC, Wieland DM, Muzik O, Degrado TR, Wolfe ER, Schwaiger M. Carbon-11 hydroxyephedrine with positron emission tomography for serial assessment of cardiac adrenergic neuronal function after acute myocardial infarction in humans. J Am Coll Cardiol. 1993 Aug; 22(2):368-75. PMID: 8335806.
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    91. DeGrado TR, Hutchins GD, Toorongian SA, Wieland DM, Schwaiger M. Myocardial kinetics of carbon-11-meta-hydroxyephedrine: retention mechanisms and effects of norepinephrine. J Nucl Med. 1993 Aug; 34(8):1287-93. PMID: 8326386.
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    92. Melon PG, Beanlands RS, DeGrado TR, Nguyen N, Petry NA, Schwaiger M. Comparison of technetium-99m sestamibi and thallium-201 retention characteristics in canine myocardium. J Am Coll Cardiol. 1992 Nov 01; 20(5):1277-83. PMID: 1401632.
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    93. DeGrado TR, Moka DC. Non-beta-oxidizable omega-[18F]fluoro long chain fatty acid analogs show cytochrome P-450-mediated defluorination: implications for the design of PET tracers of myocardial fatty acid utilization. Int J Rad Appl Instrum B. 1992 Apr; 19(3):389-97. PMID: 1629027.
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    94. DeGrado TR, Coenen HH, Stocklin G. 14(R,S)-[18F]fluoro-6-thia-heptadecanoic acid (FTHA): evaluation in mouse of a new probe of myocardial utilization of long chain fatty acids. J Nucl Med. 1991 Oct; 32(10):1888-96. PMID: 1919727.
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    95. Ng CK, Holden JE, DeGrado TR, Raffel DM, Kornguth ML, Gatley SJ. Sensitivity of myocardial fluorodeoxyglucose lumped constant to glucose and insulin. Am J Physiol. 1991 Feb; 260(2 Pt 2):H593-603. PMID: 1996702.
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    96. Gatley SJ, DeGrado TR, Kornguth ML, Holden JE. Radiopharmaceuticals for positron emission tomography. Development of new, innovative tracers for measuring the rates of physiologic and biochemical processes. Acta Radiol Suppl. 1990; 374:7-11. PMID: 1966972.
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    97. DeGrado TR, Holden JE, Gatley SJ. Catabolism of 15-(p-iodophenyl)-R,S-beta-methylpentadecanoic acid (BMIPP) by isolated rat hearts. Eur J Nucl Med. 1990; 17(3-4):188-9. PMID: 2279501.
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    98. DeGrado TR, Holden JE, Ng CK, Raffel DM, Gatley SJ. Quantitative analysis of myocardial kinetics of 15-p-[iodine-125] iodophenylpentadecanoic acid. J Nucl Med. 1989 Jul; 30(7):1211-8. PMID: 2738702.
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    99. DeGrado TR, Holden JE, Ng CK, Raffel DM, Gatley SJ. Measurement of O2 consumption in isolated organs without venous cannulation. J Appl Physiol (1985). 1989 Mar; 66(3):1316-20. PMID: 2708252.
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    100. DeGrado TR, Holden JE, Ng CK, Raffel DM, Gatley SJ. beta-Methyl-15-p-iodophenylpentadecanoic acid metabolism and kinetics in the isolated rat heart. Eur J Nucl Med. 1989; 15(2):78-80. PMID: 2920741.
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    101. Kornguth ML, Holden JE, Degrado TR, Ng CK, Raffel DM, Gatley SJ. Kinetics of [18F]1-fluoro-2,4-dinitrobenzene, a potential probe for the glutathione detoxification system, in perfused working rat heart. Int J Rad Appl Instrum B. 1989; 16(5):519-24. PMID: 2807957.
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    102. DeGrado TR, Holden JE, Ng CK, Raffel DM, Gatley SJ. Comparison of 16-iodohexadecanoic acid (IHDA) and 15-p-iodophenylpentadecanoic acid (IPPA) metabolism and kinetics in the isolated rat heart. Eur J Nucl Med. 1988; 14(12):600-6. PMID: 3243308.
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    103. Bosch AL, Degrado TR, Gatley SJ. Preparation of no carrier added fluorine-18 labeled 16-fluorohexadecanoic and fluoroacetic acids from highly reactive tetraethylammonium [18F]fluoride. Int J Rad Appl Instrum A. 1986; 37(4):305-8. PMID: 3021654.
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    104. Halama JR, Gatley SJ, DeGrado TR, Bernstein DR, Ng CK, Holden JE. Validation of 3-deoxy-3-fluoro-D-glucose as a glucose transport analogue in rat heart. Am J Physiol. 1984 Nov; 247(5 Pt 2):H754-9. PMID: 6496756.
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    105. Gatley SJ, Holden JE, Halama JR, DeGrado TR, Bernstein DR, Ng CK. Phosphorylation of glucose analog 3-O-methyl-D-glucose by rat heart. Biochem Biophys Res Commun. 1984 Mar 30; 119(3):1008-14. PMID: 6712659.
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    106. Sherratt HS, Gatley SJ, DeGrado TR, Ng CK, Holden JE. Effects of 2[5(4-chlorophenyl)pentyl]oxirane-2-carboxylate on fatty acid and glucose metabolism in perfused rat hearts determined using iodine-125 16-iodohexadecanoate. Biochem Biophys Res Commun. 1983 Dec 28; 117(3):653-7. PMID: 6667268.
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