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Laura L Pyle

TitleAssociate Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-PEDS

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Buyers E, Sass AE, Severn CD, Pyle L, Cree-Green M. 12-month Continuation of the Etonogestrel Implant in Adolescents with Polycystic Ovary Syndrome. J Pediatr Adolesc Gynecol. 2020 Sep 09. PMID: 32919086.
      View in: PubMed
    2. Champakanath A, Keshawarz A, Pyle L, Snell-Bergeon JK, Shah VN. Fracture risk assessment (FRAX) without BMD and risk of major osteoporotic fractures in adults with type 1 diabetes. Bone. 2020 Aug 24; 115614. PMID: 32853853.
      View in: PubMed
    3. Messer LH, Campbell K, Pyle L, Forlenza GP. Basal-IQ technology in the real world: satisfaction and reduction of diabetes burden in individuals with type 1 diabetes. Diabet Med. 2020 Aug 07; e14381. PMID: 32767401.
      View in: PubMed
    4. Sherk VD, Vigers T, Pyle L, Snell-Bergeon JK, Nadeau KJ, Rickels MR, Miller KM, Greenbaum CJ, Shah VN. Acute Hyperinsulinemia Alters Bone Turnover in Women and Men With Type 1 Diabetes. JBMR Plus. 2020 Sep; 4(9):e10389. PMID: 32995692.
      View in: PubMed
    5. Vinovskis C, Li LP, Prasad P, Tommerdahl K, Pyle L, Nelson RG, Pavkov ME, van Raalte D, Rewers M, Pragnell M, Mahmud FH, Cherney DZ, Johnson RJ, Nadeau KJ, Bjornstad P. Relative Hypoxia and Early Diabetic Kidney Disease in Type 1 Diabetes. Diabetes. 2020 Jul 31. PMID: 32737116.
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    6. Carreau AM, Xie D, Garcia-Reyes Y, Rahat H, Bartlette K, Behn CD, Pyle L, Nadeau KJ, Cree-Green M. Good agreement between hyperinsulinemic-euglycemic clamp and 2 hours oral minimal model assessed insulin sensitivity in adolescents. Pediatr Diabetes. 2020 Jun 26. PMID: 32592269.
      View in: PubMed
    7. Benson J, Severn C, Hudnut-Beumler J, Simon SL, Abramson N, Shomaker LB, Gulley LD, Taylor A, Kelsey MM, Nadeau KJ, Zeitler PS, Pyle L, Cree-Green M. Depression in Girls With Obesity and Polycystic Ovary Syndrome and/or Type 2 Diabetes. Can J Diabetes. 2020 Aug; 44(6):507-513. PMID: 32792104.
      View in: PubMed
    8. Jobira B, Frank DN, Pyle L, Silveira LJ, Kelsey MM, Garcia-Reyes Y, Robertson CE, Ir D, Nadeau KJ, Cree-Green M. Obese Adolescents With PCOS Have Altered Biodiversity and Relative Abundance in Gastrointestinal Microbiota. J Clin Endocrinol Metab. 2020 Jun 01; 105(6). PMID: 31970418.
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    9. Thompson T, Howell S, Davis S, Wilson R, Janusz J, Boada R, Pyle L, Tartaglia N. Current survey of early childhood intervention services in infants and young children with sex chromosome aneuploidies. Am J Med Genet C Semin Med Genet. 2020 06; 184(2):414-427. PMID: 32449585.
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    10. Simmons KM, Mitchell AM, Alkanani AA, McDaniel KA, Baschal EE, Armstrong T, Pyle L, Yu L, Michels AW. Failed Genetic Protection: Type 1 Diabetes in the Presence of HLA-DQB1*06:02. Diabetes. 2020 Aug; 69(8):1763-1769. PMID: 32439825.
      View in: PubMed
    11. Triolo TM, Pyle L, Seligova S, Yu L, Gottlieb PA, Steck AK. Risk of Islet and Celiac Autoimmunity in Cotwins of Probands With Type 1 Diabetes. J Endocr Soc. 2020 Jun 01; 4(6):bvaa053. PMID: 32537543.
      View in: PubMed
    12. Kelsey MM, Pyle L, Hilkin A, Severn CD, Utzschneider K, Van Pelt RE, Nadeau KJ, Zeitler PS. The Impact of Obesity On Insulin Sensitivity and Secretion During Pubertal Progression: A Longitudinal Study. J Clin Endocrinol Metab. 2020 May 01; 105(5). PMID: 31996919.
      View in: PubMed
    13. Polsky S, Garcetti R, Pyle L, Joshee P, Demmitt JK, Snell-Bergeon JK. Continuous glucose monitor use with and without remote monitoring in pregnant women with type 1 diabetes: A pilot study. PLoS One. 2020; 15(4):e0230476. PMID: 32298269.
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    14. Simon S, Rahat H, Carreau AM, Garcia-Reyes Y, Halbower A, Pyle L, Nadeau KJ, Cree-Green M. Poor Sleep Is Related to Metabolic Syndrome Severity in Adolescents With PCOS and Obesity. J Clin Endocrinol Metab. 2020 Apr 01; 105(4). PMID: 31901092.
      View in: PubMed
    15. Sopfe J, Vigers T, Pyle L, Giller RH, Forlenza GP. Safety and Accuracy of Factory-Calibrated Continuous Glucose Monitoring in Pediatric Patients Undergoing Hematopoietic Stem Cell Transplantation. Diabetes Technol Ther. 2020 Oct; 22(10):727-733. PMID: 32105513.
      View in: PubMed
    16. Ravi SJ, Coakley A, Vigers T, Pyle L, Forlenza GP, Alonso T. Pediatric Medicaid Patients With Type 1 Diabetes Benefit From Continuous Glucose Monitor Technology. J Diabetes Sci Technol. 2020 Mar 14; 1932296820906214. PMID: 32172603.
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    17. Chan CL, Steck AK, Severn C, Pyle L, Rewers M, Zeitler PS. Lessons From Continuous Glucose Monitoring in Youth With Pre-Type 1 Diabetes, Obesity, and Cystic Fibrosis. Diabetes Care. 2020 03; 43(3):e35-e37. PMID: 31937609.
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    18. Berget C, Messer LH, Vigers T, Frohnert BI, Pyle L, Wadwa RP, Driscoll KA, Forlenza GP. Six months of hybrid closed loop in the real-world: An evaluation of children and young adults using the 670G system. Pediatr Diabetes. 2020 03; 21(2):310-318. PMID: 31837064.
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    19. Messer LH, Berget C, Vigers T, Pyle L, Geno C, Wadwa RP, Driscoll KA, Forlenza GP. Real world hybrid closed-loop discontinuation: Predictors and perceptions of youth discontinuing the 670G system in the first 6 months. Pediatr Diabetes. 2020 03; 21(2):319-327. PMID: 31885123.
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    20. Lytvyn Y, Bjornstad P, Katz A, Singh SK, Godoy LC, Chung LT, Vinovskis CL, Pyle L, Roussel R, Perkins BA, Cherney D. SGLT2 inhibition increases serum copeptin in young adults with type 1 diabetes. Diabetes Metab. 2020 06; 46(3):203-209. PMID: 31816431.
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    21. Duca LM, Pyle L, Khanna AD, Ong T, Kahn MG, DiGuiseppi C, Scott K, Daley MF, Costa E, Davidson AJ, Crume TL. Estimating the prevalence of congenital heart disease among adolescents and adults in Colorado adjusted for incomplete case ascertainment. Am Heart J. 2020 03; 221:95-105. PMID: 31955128.
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    22. Polsky S, Garcetti R, Pyle L, Joshee P, Demmitt JK, Snell-Bergeon JK. Continuous Glucose Monitor Use With Remote Monitoring Reduces Fear of Hypoglycemia in Pregnant Women With Type 1 Diabetes: A Pilot Study. J Diabetes Sci Technol. 2020 01; 14(1):191-192. PMID: 31779476.
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    23. Cree-Green M, Wiromrat P, Stuppy JJ, Thurston J, Bergman BC, Baumgartner AD, Bacon S, Scherzinger A, Pyle L, Nadeau KJ. Muscle Insulin Resistance in Youth with Obesity and Normoglycemia is Associated with Altered Fat Metabolism. Obesity (Silver Spring). 2019 12; 27(12):2046-2054. PMID: 31659873.
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    24. Vigers T, Chan CL, Snell-Bergeon J, Bjornstad P, Zeitler PS, Forlenza G, Pyle L. cgmanalysis: An R package for descriptive analysis of continuous glucose monitor data. PLoS One. 2019; 14(10):e0216851. PMID: 31603912.
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    25. Alonso GT, Coakley A, Pyle L, Manseau K, Thomas S, Rewers A. Diabetic Ketoacidosis at Diagnosis of Type 1 Diabetes in Colorado Children, 2010-2017. Diabetes Care. 2020 01; 43(1):117-121. PMID: 31601639.
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    26. Nokoff N, Thurston J, Hilkin A, Pyle L, Zeitler PS, Nadeau KJ, Santoro N, Kelsey MM. Sex Differences in Effects of Obesity on Reproductive Hormones and Glucose Metabolism in Early Puberty. J Clin Endocrinol Metab. 2019 10 01; 104(10):4390-4397. PMID: 30985874.
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    27. Keshawarz A, Pyle L, Alman A, Sassano C, Westfeldt E, Sippl R, Snell-Bergeon J. Type 1 Diabetes Accelerates Progression of Coronary Artery Calcium Over the Menopausal Transition: The CACTI Study. Diabetes Care. 2019 12; 42(12):2315-2321. PMID: 31558547.
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    28. Srinivasan Sridhar V, Ambinathan JPN, Kretzler M, Pyle LL, Bjornstad P, Eddy S, Cherney DZ, Reich HN. Renal SGLT mRNA expression in human health and disease: a study in two cohorts. Am J Physiol Renal Physiol. 2019 11 01; 317(5):F1224-F1230. PMID: 31545924.
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    29. Wiromrat P, Bjornstad P, Vinovskis C, Chung LT, Roncal C, Pyle L, Lanaspa MA, Johnson RJ, Cherney DZ, Reznick-Lipina TK, Bishop F, Maahs DM, Wadwa RP. Elevated copeptin, arterial stiffness, and elevated albumin excretion in adolescents with type 1 diabetes. Pediatr Diabetes. 2019 12; 20(8):1110-1117. PMID: 31433534.
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    30. Carreau AM, Pyle L, Garcia-Reyes Y, Rahat H, Vigers T, Jensen T, Scherzinger A, Nadeau KJ, Cree-Green M. Clinical prediction score of nonalcoholic fatty liver disease in adolescent girls with polycystic ovary syndrome (PCOS-HS index). Clin Endocrinol (Oxf). 2019 10; 91(4):544-552. PMID: 31301251.
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    31. Kaur H, Schneider N, Pyle L, Campbell K, Akturk HK, Shah VN. Efficacy of Hybrid Closed-Loop System in Adults with Type 1 Diabetes and Gastroparesis. Diabetes Technol Ther. 2019 12; 21(12):736-739. PMID: 31347928.
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    32. Simmons KM, Fouts A, Pyle L, Clark P, Dong F, Yu L, Usmani-Brown S, Gottlieb P, Herold KC, Steck AK. Unmethylated Insulin as an Adjunctive Marker of Beta Cell Death and Progression to Type 1 Diabetes in Participants at Risk for Diabetes. Int J Mol Sci. 2019 08 08; 20(16). PMID: 31398795.
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    33. Cree-Green M, Bergman BC, Cengiz E, Fox LA, Hannon TS, Miller K, Nathan B, Pyle L, Kahn D, Tansey M, Tichy E, Tsalikian E, Libman I, Nadeau KJ. Metformin Improves Peripheral Insulin Sensitivity in Youth With Type 1 Diabetes. J Clin Endocrinol Metab. 2019 08 01; 104(8):3265-3278. PMID: 30938764.
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    34. Simon SL, McWhirter L, Diniz Behn C, Bubar KM, Kaar JL, Pyle L, Rahat H, Garcia-Reyes Y, Carreau AM, Wright KP, Nadeau KJ, Cree-Green M. Morning Circadian Misalignment Is Associated With Insulin Resistance in Girls With Obesity and Polycystic Ovarian Syndrome. J Clin Endocrinol Metab. 2019 08 01; 104(8):3525-3534. PMID: 30888398.
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    35. Cree-Green M, Ravi S, Carreau AM, Sewell R, Baumgartner A, Coe G, Bergman BC, Scherzinger A, Jensen T, Pyle L, Nadeau KJ. Nonalcoholic fatty liver disease in obese adolescent females is associated with multi-tissue insulin resistance and visceral adiposity markers. Metabol Open. 2019 Jun; 2:100011. PMID: 32812939.
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    36. Wiromrat P, Bjornstad P, Roncal C, Pyle L, Johnson RJ, Cherney DZ, Lipina T, Bishop F, Maahs DM, Wadwa RP. Serum uromodulin is associated with urinary albumin excretion in adolescents with type 1 diabetes. J Diabetes Complications. 2019 09; 33(9):648-650. PMID: 31253490.
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    37. Stanek KR, Youngkin EM, Pyle LL, Raymond JK, Driscoll KA, Majidi S. Prevalence, characteristics, and diabetes management in children with comorbid autism spectrum disorder and type 1 diabetes. Pediatr Diabetes. 2019 08; 20(5):645-651. PMID: 30912248.
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    38. Pascual AB, Pyle L, Nieto J, Klingensmith GJ, Gonzalez AG. Novel, culturally sensitive, shared medical appointment model for Hispanic pediatric type 1 diabetes patients. Pediatr Diabetes. 2019 06; 20(4):468-473. PMID: 30938029.
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    39. Van Hove JLK, Freehauf CL, Ficicioglu C, Pena LDM, Moreau KL, Henthorn TK, Christians U, Jiang H, Cowan TM, Young SP, Hite M, Friederich MW, Stabler SP, Spector EB, Kronquist KE, Thomas JA, Emmett P, Harrington MJ, Pyle L, Creadon-Swindell G, Wempe MF, MacLean KN. Biomarkers of oxidative stress, inflammation, and vascular dysfunction in inherited cystathionine ß-synthase deficient homocystinuria and the impact of taurine treatment in a phase 1/2 human clinical trial. J Inherit Metab Dis. 2019 05; 42(3):424-437. PMID: 30873612.
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    40. Shah VN, Joshee P, Sippl R, Pyle L, Vigers T, Carpenter RD, Kohrt W, Snell-Bergeon JK. Type 1 diabetes onset at young age is associated with compromised bone quality. Bone. 2019 06; 123:260-264. PMID: 30936041.
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    41. Wiromrat P, Bjornstad P, Roncal C, Cree-Green M, Baumgartner A, Coe G, Reyes YG, Schäfer M, Truong U, Pyle L, Johnson RJ, Nadeau KJ. Serum uromodulin inversely associates with aortic stiffness in youth with type 1 diabetes: A brief report from EMERALD study. J Diabetes Complications. 2019 06; 33(6):434-436. PMID: 31003921.
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    42. Cree-Green M, Carreau AM, Rahat H, Garcia-Reyes Y, Bergman BC, Pyle L, Nadeau KJ. Amino acid and fatty acid metabolomic profile during fasting and hyperinsulinemia in girls with polycystic ovarian syndrome. Am J Physiol Endocrinol Metab. 2019 05 01; 316(5):E707-E718. PMID: 30753112.
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    43. Sopfe J, Pyle L, Keating AK, Campbell K, Liu AK, Wadwa RP, Verneris MR, Giller RH, Forlenza GP. Malglycemia is associated with poor outcomes in pediatric and adolescent hematopoietic stem cell transplant patients. Blood Adv. 2019 02 12; 3(3):350-359. PMID: 30718242.
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    44. Hsu SC, Bartz S, Pyle L, Fete M, Davis S, Ohman-Hanson R, Fete TJ, Motil KJ. Growth failure in focal dermal hypoplasia. . 2019 04; 179(4):628-633. PMID: 30693654.
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    45. Cree-Green M, Wiromrat P, Stuppy JJ, Thurston J, Bergman BC, Baumgartner AD, Bacon S, Scherzinger A, Pyle L, Nadeau KJ. Youth with type 2 diabetes have hepatic, peripheral, and adipose insulin resistance. Am J Physiol Endocrinol Metab. 2019 02 01; 316(2):E186-E195. PMID: 30562061.
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    46. Bjornstad P, Schäfer M, Truong U, Cree-Green M, Pyle L, Baumgartner A, Garcia Reyes Y, Maniatis A, Nayak S, Wadwa RP, Browne LP, Reusch JEB, Nadeau KJ. Metformin Improves Insulin Sensitivity and Vascular Health in Youth With Type 1 Diabetes Mellitus. Circulation. 2018 12 18; 138(25):2895-2907. PMID: 30566007.
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    47. Simon SL, Behn CD, Cree-Green M, Kaar JL, Pyle L, Hawkins SMM, Rahat H, Garcia-Reyes Y, Wright KP, Nadeau KJ. Too Late and Not Enough: School Year Sleep Duration, Timing, and Circadian Misalignment Are Associated with Reduced Insulin Sensitivity in Adolescents with Overweight/Obesity. J Pediatr. 2019 02; 205:257-264.e1. PMID: 30497764.
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    48. Cree-Green M, Cai N, Thurston JE, Coe GV, Newnes L, Garcia-Reyes Y, Baumgartner AD, Pyle L, Nadeau KJ. Using simple clinical measures to predict insulin resistance or hyperglycemia in girls with polycystic ovarian syndrome. Pediatr Diabetes. 2018 12; 19(8):1370-1378. PMID: 30246333.
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    49. Cree-Green M, Stuppy JJ, Thurston J, Bergman BC, Coe GV, Baumgartner AD, Bacon S, Scherzinger A, Pyle L, Nadeau KJ. Youth With Type 1 Diabetes Have Adipose, Hepatic, and Peripheral Insulin Resistance. J Clin Endocrinol Metab. 2018 10 01; 103(10):3647-3657. PMID: 30020457.
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    50. Li A, Vigers T, Pyle L, Zemanick E, Nadeau K, Sagel SD, Chan CL. Continuous glucose monitoring in youth with cystic fibrosis treated with lumacaftor-ivacaftor. J Cyst Fibros. 2019 01; 18(1):144-149. PMID: 30104123.
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    51. McClain MR, Klingensmith GJ, Anderson B, Berget C, Cain C, Shea J, Campbell K, Pyle L, Raymond JK. Team Clinic: Group Approach to Care of Early Adolescents With Type 1 Diabetes. Diabetes Spectr. 2018 Aug; 31(3):273-278. PMID: 30140144.
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    52. Simon SL, Vigers T, Campbell K, Pyle L, Branscomb R, Nadeau KJ, Chan CL. Reduced insulin sensitivity is correlated with impaired sleep in adolescents with cystic fibrosis. Pediatr Diabetes. 2018 11; 19(7):1183-1190. PMID: 30022572.
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    53. Triolo TM, Fouts A, Pyle L, Yu L, Gottlieb PA, Steck AK. Identical and Nonidentical Twins: Risk and Factors Involved in Development of Islet Autoimmunity and Type 1 Diabetes. Diabetes Care. 2019 02; 42(2):192-199. PMID: 30061316.
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    54. Bjornstad P, Pyle L, Cherney DZI, Johnson RJ, Sippl R, Wong R, Rewers M, Snell-Bergeon JK. Plasma biomarkers improve prediction of diabetic kidney disease in adults with type 1 diabetes over a 12-year follow-up: CACTI study. Nephrol Dial Transplant. 2018 07 01; 33(7):1189-1196. PMID: 28992280.
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    55. Kaur H, Joshee P, Franquemont S, Baumgartner A, Thurston J, Pyle L, Nadeau KJ, Shah VN. Bone mineral content and bone density is lower in adolescents with type 1 diabetes: A brief report from the RESISTANT and EMERALD studies. J Diabetes Complications. 2018 Oct; 32(10):931-933. PMID: 29980432.
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    56. Cree-Green M, Xie D, Rahat H, Garcia-Reyes Y, Bergman BC, Scherzinger A, Diniz Behn C, Chan CL, Kelsey MM, Pyle L, Nadeau KJ. Oral Glucose Tolerance Test Glucose Peak Time Is Most Predictive of Prediabetes and Hepatic Steatosis in Obese Girls. J Endocr Soc. 2018 Jun 01; 2(6):547-562. PMID: 29942919.
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    57. Chan CL, Hope E, Thurston J, Vigers T, Pyle L, Zeitler PS, Nadeau KJ. Hemoglobin A1c Accurately Predicts Continuous Glucose Monitoring-Derived Average Glucose in Youth and Young Adults With Cystic Fibrosis. Diabetes Care. 2018 07; 41(7):1406-1413. PMID: 29674323.
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    58. Ostrov DA, Alkanani A, McDaniel KA, Case S, Baschal EE, Pyle L, Ellis S, Pöllinger B, Seidl KJ, Shah VN, Garg SK, Atkinson MA, Gottlieb PA, Michels AW. Methyldopa blocks MHC class II binding to disease-specific antigens in autoimmune diabetes. J Clin Invest. 2018 05 01; 128(5):1888-1902. PMID: 29438107.
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    59. Bjornstad P, Maahs DM, Roncal CA, Snell-Bergeon JK, Shah VN, Milagres T, Ellis SL, Hatch M, Chung LT, Rewers MJ, Garg S, Cherney DZ, Pyle L, Nadeau KJ, Johnson RJ. Role of bicarbonate supplementation on urine uric acid crystals and diabetic tubulopathy in adults with type 1 diabetes. Diabetes Obes Metab. 2018 07; 20(7):1776-1780. PMID: 29498467.
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    60. Chan CL, Vigers T, Pyle L, Zeitler PS, Sagel SD, Nadeau KJ. Continuous glucose monitoring abnormalities in cystic fibrosis youth correlate with pulmonary function decline. J Cyst Fibros. 2018 11; 17(6):783-790. PMID: 29580828.
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    61. Nomura Y, Garcia M, Child J, Hurst AL, Hyman D, Poppy A, Palmer C, Ranade D, Pyle L, Parker SK. Effect of provider-selected order indications on appropriateness of antimicrobial orders in a pediatric hospital. Am J Health Syst Pharm. 2018 02 15; 75(4):213-221. PMID: 29436467.
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    62. Majidi S, Fouts A, Pyle L, Chambers C, Armstrong T, Wang Z, Batish SD, Klingensmith G, Steck AK. Can Biomarkers Help Target Maturity-Onset Diabetes of the Young Genetic Testing in Antibody-Negative Diabetes? Diabetes Technol Ther. 2018 02; 20(2):106-112. PMID: 29355436.
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    63. Millstein RJ, Pyle LL, Bergman BC, Eckel RH, Maahs DM, Rewers MJ, Schauer IE, Snell-Bergeon JK. Sex-specific differences in insulin resistance in type 1 diabetes: The CACTI cohort. J Diabetes Complications. 2018 04; 32(4):418-423. PMID: 29449137.
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    64. Alonso GT, Hink R, De Georgeo MR, Vidal K, Thomas S, Swaschnig D, Spiegel G, Owen S, Thurston J, Pyle L, Slover R. Improving the Insulin Pump Initiation Process for Pediatric Patients with Type 1 Diabetes through Application of Lean Quality Improvement Methods. Perm J. 2018; 22:17-147. PMID: 30005730.
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    65. Shah VN, Sippl R, Joshee P, Pyle L, Kohrt WM, Schauer IE, Snell-Bergeon JK. Trabecular bone quality is lower in adults with type 1 diabetes and is negatively associated with insulin resistance. Osteoporos Int. 2018 03; 29(3):733-739. PMID: 29290026.
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    66. Bjornstad P, Cree-Green M, Baumgartner A, Coe G, Reyes YG, Schäfer M, Pyle L, Regensteiner JG, Reusch JE, Nadeau KJ. Achieving ADA/ISPAD clinical guideline goals is associated with higher insulin sensitivity and cardiopulmonary fitness in adolescents with type 1 diabetes: Results from RESistance to InSulin in Type 1 ANd Type 2 diabetes (RESISTANT) and Effects of MEtformin on CardiovasculaR Function in AdoLescents with Type 1 Diabetes (EMERALD) Studies. Pediatr Diabetes. 2018 05; 19(3):436-442. PMID: 29082640.
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    67. Spruiell MD, Searns JB, Heare TC, Roberts JL, Wylie E, Pyle L, Donaldson N, Stewart JR, Heizer H, Reese J, Scott HF, Pearce K, Anderson CJ, Erickson M, Parker SK. Clinical Care Guideline for Improving Pediatric Acute Musculoskeletal Infection Outcomes. J Pediatric Infect Dis Soc. 2017 Sep 01; 6(3):e86-e93. PMID: 28419275.
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    68. Young BE, Patinkin ZW, Pyle L, de la Houssaye B, Davidson BS, Geraghty S, Morrow AL, Krebs N. Markers of Oxidative Stress in Human Milk do not Differ by Maternal BMI But are Related to Infant Growth Trajectories. Matern Child Health J. 2017 06; 21(6):1367-1376. PMID: 28138825.
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    69. Cree-Green M, Rahat H, Newcomer BR, Bergman BC, Brown MS, Coe GV, Newnes L, Garcia-Reyes Y, Bacon S, Thurston JE, Pyle L, Scherzinger A, Nadeau KJ. Insulin Resistance, Hyperinsulinemia, and Mitochondria Dysfunction in Nonobese Girls With Polycystic Ovarian Syndrome. J Endocr Soc. 2017 Jul 01; 1(7):931-944. PMID: 29264544.
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    70. Messacar K, Campbell K, Pearce K, Pyle L, Hurst AL, Child J, Parker SK. A Handshake From Antimicrobial Stewardship Opens Doors for Infectious Disease Consultations. Clin Infect Dis. 2017 May 15; 64(10):1449-1452. PMID: 28186533.
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    71. Alonso GT, Pyle L, Frohnert B. Change in hemoglobin A1c one year following the 2014 American Diabetes Association guideline update. Diabetes Res Clin Pract. 2017 Jul; 129:169-172. PMID: 28528078.
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    72. Cree-Green M, Cai N, Pyle L, Ringham B, Brown MS, Newcomer BR, Nadeau KJ, Dabelea D. Insulin Resistance in Youth Without Diabetes Is Not Related to Muscle Mitochondrial Dysfunction. J Clin Endocrinol Metab. 2017 05 01; 102(5):1652-1660. PMID: 28204552.
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    73. Maddux AB, Hiller TD, Overdier KH, Pyle LL, Douglas IS. Innate Immune Function and Organ Failure Recovery in Adults With Sepsis. J Intensive Care Med. 2019 Jun; 34(6):486-494. PMID: 28372498.
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    74. Bjornstad P, Cree-Green M, Baumgartner A, Coe G, Reyes YG, Schafer M, Pyle L, Regensteiner JG, Reusch JEB, Nadeau KJ. Leptin is associated with cardiopulmonary fitness independent of body-mass index and insulin sensitivity in adolescents with type 1 diabetes: a brief report from the EMERALD study. J Diabetes Complications. 2017 May; 31(5):850-853. PMID: 28336216.
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    75. Hurst AL, Olson D, Somme S, Child J, Pyle L, Ranade D, Stamatoiu A, Crombleholme T, Parker SK. Once-Daily Ceftriaxone Plus Metronidazole Versus Ertapenem and/or Cefoxitin for Pediatric Appendicitis. J Pediatric Infect Dis Soc. 2017 Mar 01; 6(1):57-64. PMID: 26703242.
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    76. Stewart CL, Acker SN, Pyle L, Smith DS, Bensard DD, Moulton SL. Mapping pediatric injuries to target prevention, education, and outreach. J Pediatr Surg. 2017 Aug; 52(8):1287-1291. PMID: 28073490.
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    77. Bjornstad P, Johnson RJ, Snell-Bergeon JK, Pyle L, Davis A, Foster N, Cherney DZ, Maahs DM. Albuminuria is associated with greater copeptin concentrations in men with type 1 diabetes: A brief report from the T1D exchange Biobank. J Diabetes Complications. 2017 Feb; 31(2):387-389. PMID: 27979439.
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    78. Forlenza GP, Pyle LL, Maahs DM, Dunn TC. Ambulatory glucose profile analysis of the juvenile diabetes research foundation continuous glucose monitoring dataset-Applications to the pediatric diabetes population. Pediatr Diabetes. 2017 Nov; 18(7):622-628. PMID: 27878929.
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    79. Chan CL, Pyle L, Kelsey MM, Newnes L, Baumgartner A, Zeitler PS, Nadeau KJ. Alternate glycemic markers reflect glycemic variability in continuous glucose monitoring in youth with prediabetes and type 2 diabetes. Pediatr Diabetes. 2017 Nov; 18(7):629-636. PMID: 27873436.
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    80. Milan M, Jhajj S, Stewart C, Pyle L, Moulton S. Helmet use and injury severity among pediatric skiers and snowboarders in Colorado. J Pediatr Surg. 2017 Feb; 52(2):349-353. PMID: 27876383.
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    81. Cree-Green M, Bergman BC, Coe GV, Newnes L, Baumgartner AD, Bacon S, Sherzinger A, Pyle L, Nadeau KJ. Hepatic Steatosis is Common in Adolescents with Obesity and PCOS and Relates to De Novo Lipogenesis but not Insulin Resistance. Obesity (Silver Spring). 2016 11; 24(11):2399-2406. PMID: 27804265.
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    82. Cree-Green M, Gupta A, Coe GV, Baumgartner AD, Pyle L, Reusch JE, Brown MS, Newcomer BR, Nadeau KJ. Insulin resistance in type 2 diabetes youth relates to serum free fatty acids and muscle mitochondrial dysfunction. J Diabetes Complications. 2017 01; 31(1):141-148. PMID: 27839922.
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    83. Mullin BC, Pyle L, Haraden D, Riederer J, Brim N, Kaplan D, Novins D. A Preliminary Multimethod Comparison of Sleep Among Adolescents With and Without Generalized Anxiety Disorder. J Clin Child Adolesc Psychol. 2017 Mar-Apr; 46(2):198-210. PMID: 27736237.
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    84. Baldelli L, Flitter B, Pyle L, Maahs DM, Klingensmith G, Slover R, Alonso GT. A survey of youth with new onset type 1 diabetes: Opportunities to reduce diabetic ketoacidosis. Pediatr Diabetes. 2017 Nov; 18(7):547-552. PMID: 27726268.
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    85. Davis S, Lahlou N, Bardsley M, Temple MC, Kowal K, Pyle L, Zeitler P, Ross J. Gonadal function is associated with cardiometabolic health in pre-pubertal boys with Klinefelter syndrome. Andrology. 2016 11; 4(6):1169-1177. PMID: 27637014.
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    86. Ohman-Hanson RA, Cree-Green M, Kelsey MM, Bessesen DH, Sharp TA, Pyle L, Pereira RI, Nadeau KJ. Ethnic and Sex Differences in Adiponectin: From Childhood to Adulthood. J Clin Endocrinol Metab. 2016 12; 101(12):4808-4815. PMID: 27603898.
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    87. Chan CL, Pyle L, Morehead R, Baumgartner A, Cree-Green M, Nadeau KJ. The role of glycemia in insulin resistance in youth with type 1 and type 2 diabetes. Pediatr Diabetes. 2017 Sep; 18(6):470-477. PMID: 27503277.
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    88. Bacha F, Gidding SS, Pyle L, Levitt Katz L, Kriska A, Nadeau KJ, Lima JAC. Relationship of Cardiac Structure and Function to Cardiorespiratory Fitness and Lean Body Mass in Adolescents and Young Adults with Type 2 Diabetes. J Pediatr. 2016 10; 177:159-166.e1. PMID: 27499218.
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    89. Fouts A, Pyle L, Yu L, Miao D, Michels A, Krischer J, Sosenko J, Gottlieb P, Steck AK. Do Electrochemiluminescence Assays Improve Prediction of Time to Type 1 Diabetes in Autoantibody-Positive TrialNet Subjects? Diabetes Care. 2016 Oct; 39(10):1738-44. PMID: 27456836.
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    90. Bjornstad P, Pyle L, Kinney GL, Rewers M, Johnson RJ, Maahs DM, Snell-Bergeon JK. Adiponectin is associated with early diabetic kidney disease in adults with type 1 diabetes: A Coronary Artery Calcification in Type 1 Diabetes (CACTI) Study. J Diabetes Complications. 2017 Feb; 31(2):369-374. PMID: 27368123.
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    91. Murphy JL, Fenn N, Pyle L, Heizer H, Hughes S, Nomura Y, Child J, Parker SK. Adverse Events in Pediatric Patients Receiving Long-term Oral and Intravenous Antibiotics. Hosp Pediatr. 2016 Jun; 6(6):330-8. PMID: 27220835.
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    92. Karlin AW, Ly TT, Pyle L, Forlenza GP, Messer L, Wadwa RP, DeSalvo DJ, Payne SL, Hanes S, Clinton P, Maahs DM, Buckingham B. Duration of Infusion Set Survival in Lipohypertrophy Versus Nonlipohypertrophied Tissue in Patients with Type 1 Diabetes. Diabetes Technol Ther. 2016 07; 18(7):429-35. PMID: 27227290.
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    93. Bjornstad P, Truong U, Pyle L, Dorosz JL, Cree-Green M, Baumgartner A, Coe G, Regensteiner JG, Reusch JE, Nadeau KJ. Youth with type 1 diabetes have worse strain and less pronounced sex differences in early echocardiographic markers of diabetic cardiomyopathy compared to their normoglycemic peers: A RESistance to InSulin in Type 1 ANd Type 2 diabetes (RESISTANT) Study. J Diabetes Complications. 2016 08; 30(6):1103-10. PMID: 27133451.
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    94. Bjornstad P, Truong U, Dorosz JL, Cree-Green M, Baumgartner A, Coe G, Pyle L, Regensteiner JG, Reusch JE, Nadeau KJ. Cardiopulmonary Dysfunction and Adiponectin in Adolescents With Type 2 Diabetes. J Am Heart Assoc. 2016 Mar 18; 5(3):e002804. PMID: 26994128.
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    95. Ljunggren P, Maahs DM, Johansson P, Ludvigsson J, Pyle L, Sippl R, Wadwa RP, Snell-Bergeon J. Reduced brachial artery distensibility in patients with type 1 diabetes. J Diabetes Complications. 2016 07; 30(5):893-7. PMID: 27056753.
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    96. Triolo TM, Maahs DM, Pyle L, Slover R, Buckingham B, Cheng P, DiMeglio LA, Bremer AA, Weinzimer SA, Chase HP. Effects of Frequency of Sensor-Augmented Pump Use on HbA1c and C-Peptide Levels in the First Year of Type 1 Diabetes. Diabetes Care. 2016 04; 39(4):e61-2. PMID: 26895885.
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    97. Bjornstad P, Maahs DM, Duca LM, Pyle L, Rewers M, Johnson RJ, Snell-Bergeon JK. Estimated insulin sensitivity predicts incident micro- and macrovascular complications in adults with type 1 diabetes over 6 years: the coronary artery calcification in type 1 diabetes study. J Diabetes Complications. 2016 May-Jun; 30(4):586-90. PMID: 26936306.
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    98. Pyle L, Bergman BC, Nadeau KJ, Cree-Green M. Modeling changes in glucose and glycerol rates of appearance when true basal rates of appearance cannot be readily determined. Am J Physiol Endocrinol Metab. 2016 Mar 01; 310(5):E323-31. PMID: 26714848.
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    99. Bjornstad P, Roncal C, Milagres T, Pyle L, Lanaspa MA, Bishop FK, Snell-Bergeon JK, Johnson RJ, Wadwa RP, Maahs DM. Hyperfiltration and uricosuria in adolescents with type 1 diabetes. Pediatr Nephrol. 2016 May; 31(5):787-93. PMID: 26701836.
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    100. Klingensmith GJ, Pyle L, Nadeau KJ, Barbour LA, Goland RS, Willi SM, Linder B, White NH. Pregnancy Outcomes in Youth With Type 2 Diabetes: The TODAY Study Experience. Diabetes Care. 2016 Jan; 39(1):122-9. PMID: 26628417.
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    101. Stewart CL, Acker SN, Pyle LL, Kulungowski A, Cadnapaphornchai M, Bruny JL, Karrer F. Factors associated with peritoneal dialysis catheter complications in children. J Pediatr Surg. 2016 Jan; 51(1):159-62. PMID: 26572851.
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    102. Maahs DM, DeSalvo D, Pyle L, Ly T, Messer L, Clinton P, Westfall E, Wadwa RP, Buckingham B. Effect of acetaminophen on CGM glucose in an outpatient setting. Diabetes Care. 2015 Oct; 38(10):e158-9. PMID: 26269199.
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    103. Bjornstad P, Eckel RH, Pyle L, Rewers M, Maahs DM, Snell-Bergeon JK. Relation of Combined Non-High-Density Lipoprotein Cholesterol and Apolipoprotein B With Atherosclerosis in Adults With Type 1 Diabetes Mellitus. Am J Cardiol. 2015 Oct 01; 116(7):1057-62. PMID: 26251001.
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    104. Cree-Green M, Maahs DM, Ferland A, Hokanson JE, Wang H, Pyle L, Kinney GL, King M, Eckel RH, Nadeau KJ. Lipoprotein subfraction cholesterol distribution is more atherogenic in insulin resistant adolescents with type 1 diabetes. Pediatr Diabetes. 2016 06; 17(4):257-65. PMID: 26080650.
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    105. Bjornstad P, Cherney DZ, Snell-Bergeon JK, Pyle L, Rewers M, Johnson RJ, Maahs DM. Rapid GFR decline is associated with renal hyperfiltration and impaired GFR in adults with Type 1 diabetes. Nephrol Dial Transplant. 2015 Oct; 30(10):1706-11. PMID: 26050268.
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    106. Cree-Green M, Newcomer BR, Coe G, Newnes L, Baumgartner A, Brown MS, Pyle L, Reusch JE, Nadeau KJ. Peripheral insulin resistance in obese girls with hyperandrogenism is related to oxidative phosphorylation and elevated serum free fatty acids. Am J Physiol Endocrinol Metab. 2015 May 01; 308(9):E726-33. PMID: 25714677.
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    107. Kelsey MM, Geffner ME, Guandalini C, Pyle L, Tamborlane WV, Zeitler PS, White NH. Presentation and effectiveness of early treatment of type 2 diabetes in youth: lessons from the TODAY study. Pediatr Diabetes. 2016 May; 17(3):212-21. PMID: 25690268.
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    108. Chan CL, Pyle L, Kelsey M, Newnes L, Zeitler PS, Nadeau KJ. Screening for type 2 diabetes and prediabetes in obese youth: evaluating alternate markers of glycemia - 1,5-anhydroglucitol, fructosamine, and glycated albumin. Pediatr Diabetes. 2016 May; 17(3):206-11. PMID: 25652226.
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    109. Bjornstad P, Pyle L, Nguyen N, Snell-Bergeon JK, Bishop FK, Wadwa RP, Maahs DM. Achieving International Society for Pediatric and Adolescent Diabetes and American Diabetes Association clinical guidelines offers cardiorenal protection for youth with type 1 diabetes. Pediatr Diabetes. 2015 Feb; 16(1):22-30. PMID: 25604668.
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    110. Stewart CL, Mulligan J, Grudic GZ, Pyle L, Moulton SL. A noninvasive computational method for fluid resuscitation monitoring in pediatric burns: a preliminary report. J Burn Care Res. 2015 Jan-Feb; 36(1):145-50. PMID: 25383980.
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    111. Bjornstad P, Nguyen N, Reinick C, Maahs DM, Bishop FK, Clements SA, Snell-Bergeon JK, Lieberman R, Pyle L, Daniels SR, Paul Wadwa R. Association of apolipoprotein B, LDL-C and vascular stiffness in adolescents with type 1 diabetes. Acta Diabetol. 2015 Jun; 52(3):611-9. PMID: 25539881.
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    112. Chan CL, Pyle L, Newnes L, Nadeau KJ, Zeitler PS, Kelsey MM. Continuous glucose monitoring and its relationship to hemoglobin A1c and oral glucose tolerance testing in obese and prediabetic youth. J Clin Endocrinol Metab. 2015 Mar; 100(3):902-10. PMID: 25532041.
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    113. Bjornstad P, Cree-Green M, Baumgartner A, Maahs DM, Cherney DZ, Pyle L, Regensteiner JG, Reusch JE, Nadeau KJ. Renal function is associated with peak exercise capacity in adolescents with type 1 diabetes. Diabetes Care. 2015 Jan; 38(1):126-31. PMID: 25414156.
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    114. Stewart CL, Metzger RR, Pyle L, Darmofal J, Scaife E, Moulton SL. Helicopter versus ground emergency medical services for the transportation of traumatically injured children. J Pediatr Surg. 2015 Feb; 50(2):347-52. PMID: 25638635.
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    115. Bjornstad P, Maahs DM, Wadwa RP, Pyle L, Rewers M, Eckel RH, Snell-Bergeon JK. Plasma triglycerides predict incident albuminuria and progression of coronary artery calcification in adults with type 1 diabetes: the Coronary Artery Calcification in Type 1 Diabetes Study. J Clin Lipidol. 2014 Nov-Dec; 8(6):576-583. PMID: 25499940.
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    116. Cree-Green M, Newcomer BR, Brown MS, Baumgartner AD, Bergman B, Drew B, Regensteiner JG, Pyle L, Reusch JE, Nadeau KJ. Delayed skeletal muscle mitochondrial ADP recovery in youth with type 1 diabetes relates to muscle insulin resistance. Diabetes. 2015 Feb; 64(2):383-92. PMID: 25157095.
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    117. Bjornstad P, Maahs DM, Cherney DZ, Cree-Green M, West A, Pyle L, Nadeau KJ. Insulin sensitivity is an important determinant of renal health in adolescents with type 2 diabetes. Diabetes Care. 2014 Nov; 37(11):3033-9. PMID: 25071077.
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    118. Bjornstad P, Maahs DM, Rivard CJ, Pyle L, Rewers M, Johnson RJ, Snell-Bergeon JK. Serum uric acid predicts vascular complications in adults with type 1 diabetes: the coronary artery calcification in type 1 diabetes study. Acta Diabetol. 2014 Oct; 51(5):783-91. PMID: 24929955.
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    119. Maahs DM, Bushman L, Kerr B, Ellis SL, Pyle L, McFann K, Bouffard A, Bishop FK, Nguyen N, Anderson PL. A practical method to measure GFR in people with type 1 diabetes. J Diabetes Complications. 2014 Sep-Oct; 28(5):667-73. PMID: 25027389.
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    120. Bjornstad P, McQueen RB, Snell-Bergeon JK, Cherney D, Pyle L, Perkins B, Rewers M, Maahs DM. Fasting blood glucose--a missing variable for GFR-estimation in type 1 diabetes? PLoS One. 2014; 9(4):e96264. PMID: 24781861.
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    121. Lindquist KA, Chow K, West A, Pyle L, Isbell TS, Cree-Green M, Nadeau KJ. The StatStrip glucose monitor is suitable for use during hyperinsulinemic euglycemic clamps in a pediatric population. Diabetes Technol Ther. 2014 May; 16(5):298-302. PMID: 24471560.
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    122. Maahs DM, Chase HP, Westfall E, Slover R, Huang S, Shin JJ, Kaufman FR, Pyle L, Snell-Bergeon JK. The effects of lowering nighttime and breakfast glucose levels with sensor-augmented pump therapy on hemoglobin A1c levels in type 1 diabetes. Diabetes Technol Ther. 2014 May; 16(5):284-91. PMID: 24450776.
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    123. Levitt Katz L, Gidding SS, Bacha F, Hirst K, McKay S, Pyle L, Lima JA. Alterations in left ventricular, left atrial, and right ventricular structure and function to cardiovascular risk factors in adolescents with type 2 diabetes participating in the TODAY clinical trial. Pediatr Diabetes. 2015 Feb; 16(1):39-47. PMID: 24450390.
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    124. Zeitler P, Hirst K, Pyle L, Linder B, Copeland K, Arslanian S, Cuttler L, Nathan DM, Tollefsen S, Wilfley D, Kaufman F. A clinical trial to maintain glycemic control in youth with type 2 diabetes. N Engl J Med. 2012 Jun 14; 366(24):2247-56. PMID: 22540912.
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    125. Bacha F, Pyle L, Nadeau K, Cuttler L, Goland R, Haymond M, Levitsky L, Lynch J, Weinstock RS, White NH, Caprio S, Arslanian S. Determinants of glycemic control in youth with type 2 diabetes at randomization in the TODAY study. Pediatr Diabetes. 2012 Aug; 13(5):376-83. PMID: 22332798.
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    126. Copeland KC, Zeitler P, Geffner M, Guandalini C, Higgins J, Hirst K, Kaufman FR, Linder B, Marcovina S, McGuigan P, Pyle L, Tamborlane W, Willi S. Characteristics of adolescents and youth with recent-onset type 2 diabetes: the TODAY cohort at baseline. J Clin Endocrinol Metab. 2011 Jan; 96(1):159-67. PMID: 20962021.
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    127. Klingensmith GJ, Pyle L, Arslanian S, Copeland KC, Cuttler L, Kaufman F, Laffel L, Marcovina S, Tollefsen SE, Weinstock RS, Linder B. The presence of GAD and IA-2 antibodies in youth with a type 2 diabetes phenotype: results from the TODAY study. Diabetes Care. 2010 Sep; 33(9):1970-5. PMID: 20519658.
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    128. Goldfine AB, Fonseca V, Jablonski KA, Pyle L, Staten MA, Shoelson SE. The effects of salsalate on glycemic control in patients with type 2 diabetes: a randomized trial. Ann Intern Med. 2010 Mar 16; 152(6):346-57. PMID: 20231565.
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    129. Jago R, McMurray RG, Bassin S, Pyle L, Bruecker S, Jakicic JM, Moe E, Murray T, Volpe SL. Modifying middle school physical education: piloting strategies to increase physical activity. Pediatr Exerc Sci. 2009 May; 21(2):171-85. PMID: 19556623.
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    130. Grey M, Schreiner B, Pyle L. Development of a diabetes education program for youth with type 2 diabetes. Diabetes Educ. 2009 Jan-Feb; 35(1):108-16. PMID: 19244566.
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