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Laura L Pyle

TitleAssociate Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-PEDS

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Vigers T, Vinovskis C, Li LP, Prasad P, Heerspink H, D'Alessandro A, Reisz JA, Piani F, Cherney DZ, van Raalte DH, Nadeau KJ, Pavkov ME, Nelson RG, Pyle L, Bjornstad P. Plasma levels of carboxylic acids are markers of early kidney dysfunction in young people with type 1 diabetes. Pediatr Nephrol. 2022 May 04. PMID: 35507146.
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    2. Melena I, Piani F, Tommerdahl KL, Severn C, Chung LT, MacDonald A, Vinovskis C, Cherney D, Pyle L, Roncal-Jimenez CA, Lanaspa MA, Rewers A, van Raalte DH, Cara-Fuentes G, Parikh CR, Nelson RG, Pavkov ME, Nadeau KJ, Johnson RJ, Bjornstad P. Aminoaciduria and metabolic dysregulation during diabetic ketoacidosis: Results from the diabetic kidney alarm (DKA) study. J Diabetes Complications. 2022 Apr 28; 108203. PMID: 35523653.
      View in: PubMed
    3. Vo M, Miller K, Bennett TD, Mourani PM, LaVelle J, Carpenter TC, Scott Watson R, Pyle LL, Maddux AB. Postdischarge health resource use in pediatric survivors of prolonged mechanical ventilation for acute respiratory illness. Pediatr Pulmonol. 2022 Apr 19. PMID: 35438830.
      View in: PubMed
    4. Davis SM, Nokoff NJ, Furniss A, Pyle L, Valentine A, Fechner P, Ikomi C, Magnusen B, Nahata L, Vogiatzi MG, Dempsey A. Population-based Assessment of Cardiometabolic-related Diagnoses in Youth With Klinefelter Syndrome: A PEDSnet Study. J Clin Endocrinol Metab. 2022 Apr 19; 107(5):e1850-e1859. PMID: 35106546.
      View in: PubMed
    5. Triolo TM, Pyle L, Broncucia H, Armstrong T, Yu L, Gottlieb PA, Steck AK. Association of High-Affinity Autoantibodies With Type 1 Diabetes High-Risk HLA Haplotypes. J Clin Endocrinol Metab. 2022 03 24; 107(4):e1510-e1517. PMID: 34850014.
      View in: PubMed
    6. Shao B, Snell-Bergeon JK, Pyle LL, Thomas KE, de Boer IH, Kothari V, Segrest J, Davidson WS, Bornfeldt KE, Heinecke JW. Pulmonary surfactant protein B carried by HDL predicts incident CVD in patients with type 1 diabetes. J Lipid Res. 2022 Apr; 63(4):100196. PMID: 35300983.
      View in: PubMed
    7. Johnson MJ, Tommerdahl KL, Vinovskis C, Waikar S, Reinicke T, Parikh CR, Obeid W, Nelson RG, van Raalte DH, Pyle L, Nadeau KJ, Bjornstad P. Relationship between biomarkers of tubular injury and intrarenal hemodynamic dysfunction in youth with type 1 diabetes. Pediatr Nephrol. 2022 Mar 14. PMID: 35286453.
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    8. Maddux AB, Mourani PM, Miller K, Carpenter TC, LaVelle J, Pyle LL, Watson RS, Bennett TD. Identifying Long-Term Morbidities and Health Trajectories After Prolonged Mechanical Ventilation in Children Using State All Payer Claims Data. Pediatr Crit Care Med. 2022 Mar 07. PMID: 35250002.
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    9. Rydin AA, Severn C, Pyle L, Dorris K, Chambers C, Stiller D, Hankinson TC, Inge T, Haemer MA, Mirsky DM, Moore J, Kelsey MM. Novel clinical algorithm for hypothalamic obesity in youth with brain tumours and factors associated with excess weight gain. Pediatr Obes. 2022 Feb 27; e12903. PMID: 35224874.
      View in: PubMed
    10. Looker HC, Pyle L, Vigers T, Severn C, Saulnier PJ, Najafian B, Mauer M, Nelson RG, Bjornstad P. Structural Lesions on Kidney Biopsy in Youth-Onset and Adult-Onset Type 2 Diabetes. Diabetes Care. 2022 02 01; 45(2):436-443. PMID: 35006272.
      View in: PubMed
    11. Chan CL, Pyle L, Vigers T, Zeitler PS, Nadeau KJ. The Relationship Between Continuous Glucose Monitoring and OGTT in Youth and Young Adults With Cystic Fibrosis. J Clin Endocrinol Metab. 2022 01 18; 107(2):e548-e560. PMID: 34537845.
      View in: PubMed
    12. Cobry EC, Reznick-Lipina T, Pyle L, Slover R, Thomas JF, Alonso GT, Wadwa RP. Diabetes Technology Use in Remote Pediatric Patients with Type 1 Diabetes Using Clinic-to-Clinic Telemedicine. Diabetes Technol Ther. 2022 01; 24(1):67-74. PMID: 34524007.
      View in: PubMed
    13. Akturk HK, Vigers T, Forlenza G, Champakanath A, Pyle L. Comparison of Cgmanalysis, a Free Open-Source Continuous Glucose Monitoring Data Management and Analysis Software, with Commercially Available CGM Platforms: Data Standardization for Diabetes Technology Research. Diabetes Technol Ther. 2022 01; 24(1):54-60. PMID: 34524001.
      View in: PubMed
    14. Sklar J, Pyle L, Snell-Bergeon JK, Garcetti R, Joshee P, Demmitt JK, Polsky S. Glycemic variability and indices of glycemic control among pregnant women with type 1 diabetes (T1D) based on the use of continuous glucose monitoring share technology. J Matern Fetal Neonatal Med. 2021 Dec 07; 1-7. PMID: 34875947.
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    15. Forlenza GP, Vigers T, Berget C, Messer LH, Lal RA, Basina M, Maahs DM, Hood K, Buckingham B, Wilson DM, Wadwa RP, Driscoll KA, Pyle L. Predicting Success with a First-Generation Hybrid Closed-Loop Artificial Pancreas System Among Children, Adolescents, and Young Adults with Type 1 Diabetes: A Model Development and Validation Study. Diabetes Technol Ther. 2022 03; 24(3):157-166. PMID: 34780306.
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    16. Shah VN, Pyle L. Lumasiran, an RNAi Therapeutic for Primary Hyperoxaluria Type 1. N Engl J Med. 2021 11 11; 385(20):e69. PMID: 34758264.
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    17. Shah VN, Snell-Bergeon JK, Demmitt JK, Joshee P, Garcetti R, Pyle L, Polsky S. Relationship Between Time-in-Range, HbA1c, and the Glucose Management Indicator in Pregnancies Complicated by Type 1 Diabetes. Diabetes Technol Ther. 2021 12; 23(12):783-790. PMID: 34524020.
      View in: PubMed
    18. Buschur EO, Campbell K, Pyle L, Garcetti R, Joshee P, Demmitt JK, Snell-Bergeon JK, Polsky S. Exploratory Analysis of Glycemic Control and Variability Over Gestation Among Pregnant Women with Type 1 Diabetes. Diabetes Technol Ther. 2021 11; 23(11):768-772. PMID: 34115946.
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    19. Anderson AM, Landry LG, Alkanani AA, Pyle L, Powers AC, Atkinson MA, Mathews CE, Roep BO, Michels AW, Nakayama M. Human islet T cells are highly reactive to preproinsulin in type 1 diabetes. Proc Natl Acad Sci U S A. 2021 10 12; 118(41). PMID: 34611019.
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    20. Pyle L, Kelsey MM. Correction to: Youth-onset type 2 diabetes: translating epidemiology into clinical trials. Diabetologia. 2021 Oct; 64(10):2354. PMID: 34309689.
      View in: PubMed
    21. Nunes-Moreno M, Buchanan C, Cole FS, Davis S, Dempsey A, Dowshen N, Furniss A, Kazak AE, Kerlek AJ, Margolis P, Pyle L, Razzaghi H, Reirden DH, Schwartz B, Sequeira GM, Nokoff NJ. Behavioral Health Diagnoses in Youth with Gender Dysphoria Compared with Controls: A PEDSnet Study. J Pediatr. 2022 02; 241:147-153.e1. PMID: 34571022.
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    22. Hwang SS, Tong S, Pyle L, Battaglia C, McManus B, Niermeyer S, Sauaia A. Impact of State Prioritization of Safe Infant Sleep Programs on Supine Sleep Positioning for Non-Hispanic White and Non-Hispanic Black Infants. Am J Perinatol. 2021 Sep 20. PMID: 34544194.
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    23. Cung S, Pyle L, Nadeau K, Dabelea D, Cree-Green M, Davis SM. In-vivo skeletal muscle mitochondrial function in Klinefelter syndrome. J Investig Med. 2022 01; 70(1):104-107. PMID: 34493629.
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    24. Piani F, Melena I, Severn C, Chung LT, Vinovskis C, Cherney D, Pyle L, Roncal-Jimenez CA, Lanaspa MA, Rewers A, van Raalte DH, Obeid W, Parikh C, Nelson RG, Pavkov ME, Nadeau KJ, Johnson RJ, Bjornstad P. Tubular injury in diabetic ketoacidosis: Results from the diabetic kidney alarm study. Pediatr Diabetes. 2021 11; 22(7):1031-1039. PMID: 34435718.
      View in: PubMed
    25. Akturk HK, Snell-Bergeon J, Pyle L, Fivekiller E, Garg S, Cobry E. Accuracy of a breath ketone analyzer to detect ketosis in adults and children with type 1 diabetes. J Diabetes Complications. 2021 11; 35(11):108030. PMID: 34481712.
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    26. Sewell R, Buchanan CL, Davis S, Christakis DA, Dempsey A, Furniss A, Kazak AE, Kerlek AJ, Magnusen B, Pajor NM, Pyle L, Pyle LC, Razzaghi H, Schwartz BI, Vogiatzi MG, Nokoff NJ. Behavioral Health Diagnoses in Youth with Differences of Sex Development or Congenital Adrenal Hyperplasia Compared with Controls: A PEDSnet Study. J Pediatr. 2021 12; 239:175-181.e2. PMID: 34461062.
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    27. Vigers T, Vanderlinden LA, Johnson RK, Carry PM, Yang I, DeFelice BC, Kaizer AM, Pyle L, Rewers M, Fiehn O, Norris JM, Kechris K. A Mediation Approach to Discovering Causal Relationships between the Metabolome and DNA Methylation in Type 1 Diabetes. Metabolites. 2021 Aug 14; 11(8). PMID: 34436483.
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    28. Messer LH, Berget C, Pyle L, Vigers T, Cobry E, Driscoll KA, Forlenza GP. Real-World Use of a New Hybrid Closed Loop Improves Glycemic Control in Youth with Type 1 Diabetes. Diabetes Technol Ther. 2021 12; 23(12):837-843. PMID: 34096789.
      View in: PubMed
    29. Kelsey MM, Hilkin A, Pyle L, Severn C, Utzschneider K, Van Pelt RE, Zeitler PS, Nadeau KJ. Two-Year Treatment With Metformin During Puberty Does Not Preserve ß-Cell Function in Youth With Obesity. J Clin Endocrinol Metab. 2021 06 16; 106(7):e2622-e2632. PMID: 33728428.
      View in: PubMed
    30. Berget C, Akturk HK, Messer LH, Vigers T, Pyle L, Snell-Bergeon J, Driscoll KA, Forlenza GP. Real-world performance of hybrid closed loop in youth, young adults, adults and older adults with type 1 diabetes: Identifying a clinical target for hybrid closed-loop use. Diabetes Obes Metab. 2021 09; 23(9):2048-2057. PMID: 34010499.
      View in: PubMed
    31. Pyle L, Kelsey MM. Youth-onset type 2 diabetes: translating epidemiology into clinical trials. Diabetologia. 2021 08; 64(8):1709-1716. PMID: 34075436.
      View in: PubMed
    32. Gourgari E, Nadeau KJ, Pyle L, Playford MP, Ma J, Mehta NN, Remaley AT, Gordon SM. Effect of metformin on the high-density lipoprotein proteome in youth with type 1 diabetes. Endocrinol Diabetes Metab. 2021 Jul; 4(3):e00261. PMID: 34277985.
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    33. Alonso GT, Murphy C, Pyle L, Thomas S, Ohman-Hanson R, Rewers A. Increased Prevalence of Diabetic Ketoacidosis Among Colorado Children at Diagnosis of Type 1 Diabetes During the COVID-19 Pandemic Lockdown Resolves After Reopening. Diabetes Technol Ther. 2021 09; 23(9):663-664. PMID: 33835859.
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    34. Hudnut-Beumler J, Kaar JL, Taylor A, Kelsey MM, Nadeau KJ, Zeitler P, Snell-Bergeon J, Pyle L, Cree-Green M. Development of type 2 diabetes in adolescent girls with polycystic ovary syndrome and obesity. Pediatr Diabetes. 2021 08; 22(5):699-706. PMID: 33870630.
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    35. Hwang SS, Tong S, Smith RA, Barfield WD, Pyle L, Battaglia C, McManus B, Niermeyer S, Sauaia A. Persistent Racial/Ethnic Disparities in Supine Sleep Positioning among US Preterm Infants, 2000-2015. J Pediatr. 2021 06; 233:51-57.e3. PMID: 33676934.
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    36. Mullin BC, Holzman JBW, Pyle L, Perks EL, Chintaluru Y, Gulley LD, Haraden DA, Hankin BL. Relationships between attention to emotion and anxiety among a community sample of adolescents. Psychol Med. 2021 Mar 01; 1-12. PMID: 33641686.
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    37. Triolo TM, Pyle L, Seligova S, Yu L, Simmons K, Gottlieb P, Evans-Molina C, Steck AK. Proinsulin:C-peptide ratio trajectories over time in relatives at increased risk of progression to type 1 diabetes. J Transl Autoimmun. 2021; 4:100089. PMID: 33748733.
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    38. Mitchell AM, Alkanani AA, McDaniel KA, Pyle L, Waugh K, Steck AK, Nakayama M, Yu L, Gottlieb PA, Rewers MJ, Michels AW. T-cell responses to hybrid insulin peptides prior to type 1 diabetes development. Proc Natl Acad Sci U S A. 2021 02 09; 118(6). PMID: 33542101.
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    39. Pyle L, Carreau AM, Rahat H, Garcia-Reyes Y, Bergman BC, Nadeau KJ, Cree-Green M. Fasting plasma metabolomic profiles are altered by three days of standardized diet and restricted physical activity. Metabol Open. 2021 Mar; 9:100085. PMID: 33665598.
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    40. Andrisse S, Garcia-Reyes Y, Pyle L, Kelsey MM, Nadeau KJ, Cree-Green M. Racial and Ethnic Differences in Metabolic Disease in Adolescents With Obesity and Polycystic Ovary Syndrome. J Endocr Soc. 2021 Apr 01; 5(4):bvab008. PMID: 33644620.
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    41. Jobira B, Frank DN, Silveira LJ, Pyle L, Kelsey MM, Garcia-Reyes Y, Robertson CE, Ir D, Nadeau KJ, Cree-Green M. Hepatic steatosis relates to gastrointestinal microbiota changes in obese girls with polycystic ovary syndrome. PLoS One. 2021; 16(1):e0245219. PMID: 33465100.
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    42. O'Donnell HK, Vigers T, Johnson SB, Pyle L, Wright N, Deeb LC, Driscoll KA. Pump It Up! A randomized clinical trial to optimize insulin pump self-management behaviors in adolescents with type 1 diabetes. Contemp Clin Trials. 2021 03; 102:106279. PMID: 33440262.
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    43. Bartlette K, Carreau AM, Xie D, Garcia-Reyes Y, Rahat H, Pyle L, Nadeau KJ, Cree-Green M, Diniz Behn C. Oral minimal model-based estimates of insulin sensitivity in obese youth depend on oral glucose tolerance test protocol duration. Metabol Open. 2021 Mar; 9:100078. PMID: 33511337.
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    44. Tommerdahl KL, Baumgartner K, Schäfer M, Bjornstad P, Melena I, Hegemann S, Baumgartner AD, Pyle L, Cree-Green M, Truong U, Browne L, Regensteiner JG, Reusch JEB, Nadeau KJ. Impact of Obesity on Measures of Cardiovascular and Kidney Health in Youth With Type 1 Diabetes as Compared With Youth With Type 2 Diabetes. Diabetes Care. 2021 03; 44(3):795-803. PMID: 33402367.
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    45. Tommerdahl KL, Bjornstad P, Kendrick J, Cree-Green M, Baumgartner AD, Pyle L, Reusch JEB, Nadeau KJ. Results from the Effects of MEtformin on cardiovasculaR function in AdoLescents with type 1 Diabetes (EMERALD) study: A brief report of kidney and inflammatory outcomes. Diabetes Obes Metab. 2021 03; 23(3):844-849. PMID: 33236509.
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    46. Levin P, Hoogwerf BJ, Snell-Bergeon J, Vigers T, Pyle L, Bromberger L. Ultra Rapid-Acting Inhaled Insulin Improves Glucose Control in Patients With Type 2 Diabetes Mellitus. Endocr Pract. 2021 May; 27(5):449-454. PMID: 33853718.
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    47. Shah VN, Pyle L, Snell-Bergeon JK. Response to Authors' concern. Bone. 2021 02; 143:115750. PMID: 33188957.
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    48. Kelsey MM, Severn C, Hilkin AM, Pyle L, Nadeau KJ, Zeitler PS. Puberty Is Associated with a Rising Hemoglobin A1c, Even in Youth with Normal Weight. J Pediatr. 2021 03; 230:244-247. PMID: 33300876.
      View in: PubMed
    49. Messer LH, Campbell K, Pyle L, Forlenza GP. Basal-IQ technology in the real world: satisfaction and reduction of diabetes burden in individuals with type 1 diabetes. Diabet Med. 2021 06; 38(6):e14381. PMID: 32767401.
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    50. Buyers E, Sass AE, Severn CD, Pyle L, Cree-Green M. Twelve-month Continuation of the Etonogestrel Implant in Adolescents With Polycystic Ovary Syndrome. J Pediatr Adolesc Gynecol. 2021 Feb; 34(1):33-39. PMID: 32919086.
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    51. Champakanath A, Keshawarz A, Pyle L, Snell-Bergeon JK, Shah VN. Fracture risk assessment (FRAX) without BMD and risk of major osteoporotic fractures in adults with type 1 diabetes. Bone. 2021 02; 143:115614. PMID: 32853853.
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    52. Sopfe J, Campbell K, Keating AK, Pyle L, Liu AK, Verneris MR, Giller RH, Forlenza GP. Glycemic variability is associated with poor outcomes in pediatric hematopoietic stem cell transplant patients. Pediatr Blood Cancer. 2020 11; 67(11):e28626. PMID: 33480469.
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    53. Sherk VD, Vigers T, Pyle L, Snell-Bergeon JK, Nadeau KJ, Rickels MR, Miller KM, Greenbaum CJ, Shah VN. Acute Hyperinsulinemia Alters Bone Turnover in Women and Men With Type 1 Diabetes. JBMR Plus. 2020 Sep; 4(9):e10389. PMID: 32995692.
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    54. Carreau AM, Xie D, Garcia-Reyes Y, Rahat H, Bartlette K, Behn CD, Pyle L, Nadeau KJ, Cree-Green M. Good agreement between hyperinsulinemic-euglycemic clamp and 2 hours oral minimal model assessed insulin sensitivity in adolescents. Pediatr Diabetes. 2020 11; 21(7):1159-1168. PMID: 32592269.
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    55. Vinovskis C, Li LP, Prasad P, Tommerdahl K, Pyle L, Nelson RG, Pavkov ME, van Raalte D, Rewers M, Pragnell M, Mahmud FH, Cherney DZ, Johnson RJ, Nadeau KJ, Bjornstad P. Relative Hypoxia and Early Diabetic Kidney Disease in Type 1 Diabetes. Diabetes. 2020 12; 69(12):2700-2708. PMID: 32737116.
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    56. Benson J, Severn C, Hudnut-Beumler J, Simon SL, Abramson N, Shomaker LB, Gulley LD, Taylor A, Kelsey MM, Nadeau KJ, Zeitler PS, Pyle L, Cree-Green M. Depression in Girls With Obesity and Polycystic Ovary Syndrome and/or Type 2 Diabetes. Can J Diabetes. 2020 Aug; 44(6):507-513. PMID: 32792104.
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    57. Jobira B, Frank DN, Pyle L, Silveira LJ, Kelsey MM, Garcia-Reyes Y, Robertson CE, Ir D, Nadeau KJ, Cree-Green M. Obese Adolescents With PCOS Have Altered Biodiversity and Relative Abundance in Gastrointestinal Microbiota. J Clin Endocrinol Metab. 2020 06 01; 105(6). PMID: 31970418.
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    58. Thompson T, Howell S, Davis S, Wilson R, Janusz J, Boada R, Pyle L, Tartaglia N. Current survey of early childhood intervention services in infants and young children with sex chromosome aneuploidies. Am J Med Genet C Semin Med Genet. 2020 06; 184(2):414-427. PMID: 32449585.
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    59. Simmons KM, Mitchell AM, Alkanani AA, McDaniel KA, Baschal EE, Armstrong T, Pyle L, Yu L, Michels AW. Failed Genetic Protection: Type 1 Diabetes in the Presence of HLA-DQB1*06:02. Diabetes. 2020 08; 69(8):1763-1769. PMID: 32439825.
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    60. Triolo TM, Pyle L, Seligova S, Yu L, Gottlieb PA, Steck AK. Risk of Islet and Celiac Autoimmunity in Cotwins of Probands With Type 1 Diabetes. J Endocr Soc. 2020 Jun 01; 4(6):bvaa053. PMID: 32537543.
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    61. Kelsey MM, Pyle L, Hilkin A, Severn CD, Utzschneider K, Van Pelt RE, Nadeau KJ, Zeitler PS. The Impact of Obesity On Insulin Sensitivity and Secretion During Pubertal Progression: A Longitudinal Study. J Clin Endocrinol Metab. 2020 05 01; 105(5). PMID: 31996919.
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    62. Polsky S, Garcetti R, Pyle L, Joshee P, Demmitt JK, Snell-Bergeon JK. Continuous glucose monitor use with and without remote monitoring in pregnant women with type 1 diabetes: A pilot study. PLoS One. 2020; 15(4):e0230476. PMID: 32298269.
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    63. Simon S, Rahat H, Carreau AM, Garcia-Reyes Y, Halbower A, Pyle L, Nadeau KJ, Cree-Green M. Poor Sleep Is Related to Metabolic Syndrome Severity in Adolescents With PCOS and Obesity. J Clin Endocrinol Metab. 2020 04 01; 105(4). PMID: 31901092.
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    64. Sopfe J, Vigers T, Pyle L, Giller RH, Forlenza GP. Safety and Accuracy of Factory-Calibrated Continuous Glucose Monitoring in Pediatric Patients Undergoing Hematopoietic Stem Cell Transplantation. Diabetes Technol Ther. 2020 10; 22(10):727-733. PMID: 32105513.
      View in: PubMed
    65. Ravi SJ, Coakley A, Vigers T, Pyle L, Forlenza GP, Alonso T. Pediatric Medicaid Patients With Type 1 Diabetes Benefit From Continuous Glucose Monitor Technology. J Diabetes Sci Technol. 2021 05; 15(3):630-635. PMID: 32172603.
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    66. Chan CL, Steck AK, Severn C, Pyle L, Rewers M, Zeitler PS. Lessons From Continuous Glucose Monitoring in Youth With Pre-Type 1 Diabetes, Obesity, and Cystic Fibrosis. Diabetes Care. 2020 03; 43(3):e35-e37. PMID: 31937609.
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    67. Berget C, Messer LH, Vigers T, Frohnert BI, Pyle L, Wadwa RP, Driscoll KA, Forlenza GP. Six months of hybrid closed loop in the real-world: An evaluation of children and young adults using the 670G system. Pediatr Diabetes. 2020 03; 21(2):310-318. PMID: 31837064.
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    68. Messer LH, Berget C, Vigers T, Pyle L, Geno C, Wadwa RP, Driscoll KA, Forlenza GP. Real world hybrid closed-loop discontinuation: Predictors and perceptions of youth discontinuing the 670G system in the first 6 months. Pediatr Diabetes. 2020 03; 21(2):319-327. PMID: 31885123.
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    69. Lytvyn Y, Bjornstad P, Katz A, Singh SK, Godoy LC, Chung LT, Vinovskis CL, Pyle L, Roussel R, Perkins BA, Cherney D. SGLT2 inhibition increases serum copeptin in young adults with type 1 diabetes. Diabetes Metab. 2020 06; 46(3):203-209. PMID: 31816431.
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    70. Duca LM, Pyle L, Khanna AD, Ong T, Kahn MG, DiGuiseppi C, Scott K, Daley MF, Costa E, Davidson AJ, Crume TL. Estimating the prevalence of congenital heart disease among adolescents and adults in Colorado adjusted for incomplete case ascertainment. Am Heart J. 2020 03; 221:95-105. PMID: 31955128.
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    71. Polsky S, Garcetti R, Pyle L, Joshee P, Demmitt JK, Snell-Bergeon JK. Continuous Glucose Monitor Use With Remote Monitoring Reduces Fear of Hypoglycemia in Pregnant Women With Type 1 Diabetes: A Pilot Study. J Diabetes Sci Technol. 2020 01; 14(1):191-192. PMID: 31779476.
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    72. Cree-Green M, Wiromrat P, Stuppy JJ, Thurston J, Bergman BC, Baumgartner AD, Bacon S, Scherzinger A, Pyle L, Nadeau KJ. Muscle Insulin Resistance in Youth with Obesity and Normoglycemia is Associated with Altered Fat Metabolism. Obesity (Silver Spring). 2019 12; 27(12):2046-2054. PMID: 31659873.
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    73. Vigers T, Chan CL, Snell-Bergeon J, Bjornstad P, Zeitler PS, Forlenza G, Pyle L. cgmanalysis: An R package for descriptive analysis of continuous glucose monitor data. PLoS One. 2019; 14(10):e0216851. PMID: 31603912.
      View in: PubMed
    74. Alonso GT, Coakley A, Pyle L, Manseau K, Thomas S, Rewers A. Diabetic Ketoacidosis at Diagnosis of Type 1 Diabetes in Colorado Children, 2010-2017. Diabetes Care. 2020 01; 43(1):117-121. PMID: 31601639.
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    75. Nokoff N, Thurston J, Hilkin A, Pyle L, Zeitler PS, Nadeau KJ, Santoro N, Kelsey MM. Sex Differences in Effects of Obesity on Reproductive Hormones and Glucose Metabolism in Early Puberty. J Clin Endocrinol Metab. 2019 10 01; 104(10):4390-4397. PMID: 30985874.
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    76. Keshawarz A, Pyle L, Alman A, Sassano C, Westfeldt E, Sippl R, Snell-Bergeon J. Type 1 Diabetes Accelerates Progression of Coronary Artery Calcium Over the Menopausal Transition: The CACTI Study. Diabetes Care. 2019 12; 42(12):2315-2321. PMID: 31558547.
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    77. Srinivasan Sridhar V, Ambinathan JPN, Kretzler M, Pyle LL, Bjornstad P, Eddy S, Cherney DZ, Reich HN. Renal SGLT mRNA expression in human health and disease: a study in two cohorts. Am J Physiol Renal Physiol. 2019 11 01; 317(5):F1224-F1230. PMID: 31545924.
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    78. Wiromrat P, Bjornstad P, Vinovskis C, Chung LT, Roncal C, Pyle L, Lanaspa MA, Johnson RJ, Cherney DZ, Reznick-Lipina TK, Bishop F, Maahs DM, Wadwa RP. Elevated copeptin, arterial stiffness, and elevated albumin excretion in adolescents with type 1 diabetes. Pediatr Diabetes. 2019 12; 20(8):1110-1117. PMID: 31433534.
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    79. Carreau AM, Pyle L, Garcia-Reyes Y, Rahat H, Vigers T, Jensen T, Scherzinger A, Nadeau KJ, Cree-Green M. Clinical prediction score of nonalcoholic fatty liver disease in adolescent girls with polycystic ovary syndrome (PCOS-HS index). Clin Endocrinol (Oxf). 2019 10; 91(4):544-552. PMID: 31301251.
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    80. Kaur H, Schneider N, Pyle L, Campbell K, Akturk HK, Shah VN. Efficacy of Hybrid Closed-Loop System in Adults with Type 1 Diabetes and Gastroparesis. Diabetes Technol Ther. 2019 12; 21(12):736-739. PMID: 31347928.
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    81. Simmons KM, Fouts A, Pyle L, Clark P, Dong F, Yu L, Usmani-Brown S, Gottlieb P, Herold KC, Steck AK. Unmethylated Insulin as an Adjunctive Marker of Beta Cell Death and Progression to Type 1 Diabetes in Participants at Risk for Diabetes. Int J Mol Sci. 2019 08 08; 20(16). PMID: 31398795.
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    86. Stanek KR, Youngkin EM, Pyle LL, Raymond JK, Driscoll KA, Majidi S. Prevalence, characteristics, and diabetes management in children with comorbid autism spectrum disorder and type 1 diabetes. Pediatr Diabetes. 2019 08; 20(5):645-651. PMID: 30912248.
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    87. Pascual AB, Pyle L, Nieto J, Klingensmith GJ, Gonzalez AG. Novel, culturally sensitive, shared medical appointment model for Hispanic pediatric type 1 diabetes patients. Pediatr Diabetes. 2019 06; 20(4):468-473. PMID: 30938029.
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    90. Wiromrat P, Bjornstad P, Roncal C, Cree-Green M, Baumgartner A, Coe G, Reyes YG, Schäfer M, Truong U, Pyle L, Johnson RJ, Nadeau KJ. Serum uromodulin inversely associates with aortic stiffness in youth with type 1 diabetes: A brief report from EMERALD study. J Diabetes Complications. 2019 06; 33(6):434-436. PMID: 31003921.
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    91. Cree-Green M, Carreau AM, Rahat H, Garcia-Reyes Y, Bergman BC, Pyle L, Nadeau KJ. Amino acid and fatty acid metabolomic profile during fasting and hyperinsulinemia in girls with polycystic ovarian syndrome. Am J Physiol Endocrinol Metab. 2019 05 01; 316(5):E707-E718. PMID: 30753112.
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    92. Sopfe J, Pyle L, Keating AK, Campbell K, Liu AK, Wadwa RP, Verneris MR, Giller RH, Forlenza GP. Malglycemia is associated with poor outcomes in pediatric and adolescent hematopoietic stem cell transplant patients. Blood Adv. 2019 02 12; 3(3):350-359. PMID: 30718242.
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    93. Hsu SC, Bartz S, Pyle L, Fete M, Davis S, Ohman-Hanson R, Fete TJ, Motil KJ. Growth failure in focal dermal hypoplasia. Am J Med Genet A. 2019 04; 179(4):628-633. PMID: 30693654.
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    96. Simon SL, Behn CD, Cree-Green M, Kaar JL, Pyle L, Hawkins SMM, Rahat H, Garcia-Reyes Y, Wright KP, Nadeau KJ. Too Late and Not Enough: School Year Sleep Duration, Timing, and Circadian Misalignment Are Associated with Reduced Insulin Sensitivity in Adolescents with Overweight/Obesity. J Pediatr. 2019 02; 205:257-264.e1. PMID: 30497764.
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    97. Cree-Green M, Cai N, Thurston JE, Coe GV, Newnes L, Garcia-Reyes Y, Baumgartner AD, Pyle L, Nadeau KJ. Using simple clinical measures to predict insulin resistance or hyperglycemia in girls with polycystic ovarian syndrome. Pediatr Diabetes. 2018 12; 19(8):1370-1378. PMID: 30246333.
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    98. Cree-Green M, Stuppy JJ, Thurston J, Bergman BC, Coe GV, Baumgartner AD, Bacon S, Scherzinger A, Pyle L, Nadeau KJ. Youth With Type 1 Diabetes Have Adipose, Hepatic, and Peripheral Insulin Resistance. J Clin Endocrinol Metab. 2018 10 01; 103(10):3647-3657. PMID: 30020457.
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    99. Li A, Vigers T, Pyle L, Zemanick E, Nadeau K, Sagel SD, Chan CL. Continuous glucose monitoring in youth with cystic fibrosis treated with lumacaftor-ivacaftor. J Cyst Fibros. 2019 01; 18(1):144-149. PMID: 30104123.
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    100. McClain MR, Klingensmith GJ, Anderson B, Berget C, Cain C, Shea J, Campbell K, Pyle L, Raymond JK. Team Clinic: Group Approach to Care of Early Adolescents With Type 1 Diabetes. Diabetes Spectr. 2018 Aug; 31(3):273-278. PMID: 30140144.
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    101. Simon SL, Vigers T, Campbell K, Pyle L, Branscomb R, Nadeau KJ, Chan CL. Reduced insulin sensitivity is correlated with impaired sleep in adolescents with cystic fibrosis. Pediatr Diabetes. 2018 11; 19(7):1183-1190. PMID: 30022572.
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    102. Triolo TM, Fouts A, Pyle L, Yu L, Gottlieb PA, Steck AK. Identical and Nonidentical Twins: Risk and Factors Involved in Development of Islet Autoimmunity and Type 1 Diabetes. Diabetes Care. 2019 02; 42(2):192-199. PMID: 30061316.
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    103. Bjornstad P, Pyle L, Cherney DZI, Johnson RJ, Sippl R, Wong R, Rewers M, Snell-Bergeon JK. Plasma biomarkers improve prediction of diabetic kidney disease in adults with type 1 diabetes over a 12-year follow-up: CACTI study. Nephrol Dial Transplant. 2018 07 01; 33(7):1189-1196. PMID: 28992280.
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    104. Kaur H, Joshee P, Franquemont S, Baumgartner A, Thurston J, Pyle L, Nadeau KJ, Shah VN. Bone mineral content and bone density is lower in adolescents with type 1 diabetes: A brief report from the RESISTANT and EMERALD studies. J Diabetes Complications. 2018 Oct; 32(10):931-933. PMID: 29980432.
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    105. Cree-Green M, Xie D, Rahat H, Garcia-Reyes Y, Bergman BC, Scherzinger A, Diniz Behn C, Chan CL, Kelsey MM, Pyle L, Nadeau KJ. Oral Glucose Tolerance Test Glucose Peak Time Is Most Predictive of Prediabetes and Hepatic Steatosis in Obese Girls. J Endocr Soc. 2018 Jun 01; 2(6):547-562. PMID: 29942919.
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    106. Chan CL, Hope E, Thurston J, Vigers T, Pyle L, Zeitler PS, Nadeau KJ. Hemoglobin A1c Accurately Predicts Continuous Glucose Monitoring-Derived Average Glucose in Youth and Young Adults With Cystic Fibrosis. Diabetes Care. 2018 07; 41(7):1406-1413. PMID: 29674323.
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    107. Ostrov DA, Alkanani A, McDaniel KA, Case S, Baschal EE, Pyle L, Ellis S, Pöllinger B, Seidl KJ, Shah VN, Garg SK, Atkinson MA, Gottlieb PA, Michels AW. Methyldopa blocks MHC class II binding to disease-specific antigens in autoimmune diabetes. J Clin Invest. 2018 05 01; 128(5):1888-1902. PMID: 29438107.
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    108. Bjornstad P, Maahs DM, Roncal CA, Snell-Bergeon JK, Shah VN, Milagres T, Ellis SL, Hatch M, Chung LT, Rewers MJ, Garg S, Cherney DZ, Pyle L, Nadeau KJ, Johnson RJ. Role of bicarbonate supplementation on urine uric acid crystals and diabetic tubulopathy in adults with type 1 diabetes. Diabetes Obes Metab. 2018 07; 20(7):1776-1780. PMID: 29498467.
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    109. Chan CL, Vigers T, Pyle L, Zeitler PS, Sagel SD, Nadeau KJ. Continuous glucose monitoring abnormalities in cystic fibrosis youth correlate with pulmonary function decline. J Cyst Fibros. 2018 11; 17(6):783-790. PMID: 29580828.
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    110. Nomura Y, Garcia M, Child J, Hurst AL, Hyman D, Poppy A, Palmer C, Ranade D, Pyle L, Parker SK. Effect of provider-selected order indications on appropriateness of antimicrobial orders in a pediatric hospital. Am J Health Syst Pharm. 2018 02 15; 75(4):213-221. PMID: 29436467.
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    111. Majidi S, Fouts A, Pyle L, Chambers C, Armstrong T, Wang Z, Batish SD, Klingensmith G, Steck AK. Can Biomarkers Help Target Maturity-Onset Diabetes of the Young Genetic Testing in Antibody-Negative Diabetes? Diabetes Technol Ther. 2018 02; 20(2):106-112. PMID: 29355436.
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    112. Millstein RJ, Pyle LL, Bergman BC, Eckel RH, Maahs DM, Rewers MJ, Schauer IE, Snell-Bergeon JK. Sex-specific differences in insulin resistance in type 1 diabetes: The CACTI cohort. J Diabetes Complications. 2018 04; 32(4):418-423. PMID: 29449137.
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    113. Alonso GT, Hink R, De Georgeo MR, Vidal K, Thomas S, Swaschnig D, Spiegel G, Owen S, Thurston J, Pyle L, Slover R. Improving the Insulin Pump Initiation Process for Pediatric Patients with Type 1 Diabetes through Application of Lean Quality Improvement Methods. Perm J. 2018; 22:17-147. PMID: 30005730.
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    114. Shah VN, Sippl R, Joshee P, Pyle L, Kohrt WM, Schauer IE, Snell-Bergeon JK. Trabecular bone quality is lower in adults with type 1 diabetes and is negatively associated with insulin resistance. Osteoporos Int. 2018 03; 29(3):733-739. PMID: 29290026.
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    115. Bjornstad P, Cree-Green M, Baumgartner A, Coe G, Reyes YG, Schäfer M, Pyle L, Regensteiner JG, Reusch JE, Nadeau KJ. Achieving ADA/ISPAD clinical guideline goals is associated with higher insulin sensitivity and cardiopulmonary fitness in adolescents with type 1 diabetes: Results from RESistance to InSulin in Type 1 ANd Type 2 diabetes (RESISTANT) and Effects of MEtformin on CardiovasculaR Function in AdoLescents with Type 1 Diabetes (EMERALD) Studies. Pediatr Diabetes. 2018 05; 19(3):436-442. PMID: 29082640.
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    116. Spruiell MD, Searns JB, Heare TC, Roberts JL, Wylie E, Pyle L, Donaldson N, Stewart JR, Heizer H, Reese J, Scott HF, Pearce K, Anderson CJ, Erickson M, Parker SK. Clinical Care Guideline for Improving Pediatric Acute Musculoskeletal Infection Outcomes. J Pediatric Infect Dis Soc. 2017 Sep 01; 6(3):e86-e93. PMID: 28419275.
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    117. Young BE, Patinkin ZW, Pyle L, de la Houssaye B, Davidson BS, Geraghty S, Morrow AL, Krebs N. Markers of Oxidative Stress in Human Milk do not Differ by Maternal BMI But are Related to Infant Growth Trajectories. Matern Child Health J. 2017 06; 21(6):1367-1376. PMID: 28138825.
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    118. Cree-Green M, Rahat H, Newcomer BR, Bergman BC, Brown MS, Coe GV, Newnes L, Garcia-Reyes Y, Bacon S, Thurston JE, Pyle L, Scherzinger A, Nadeau KJ. Insulin Resistance, Hyperinsulinemia, and Mitochondria Dysfunction in Nonobese Girls With Polycystic Ovarian Syndrome. J Endocr Soc. 2017 Jul 01; 1(7):931-944. PMID: 29264544.
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    119. Messacar K, Campbell K, Pearce K, Pyle L, Hurst AL, Child J, Parker SK. A Handshake From Antimicrobial Stewardship Opens Doors for Infectious Disease Consultations. Clin Infect Dis. 2017 May 15; 64(10):1449-1452. PMID: 28186533.
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    120. Alonso GT, Pyle L, Frohnert B. Change in hemoglobin A1c one year following the 2014 American Diabetes Association guideline update. Diabetes Res Clin Pract. 2017 Jul; 129:169-172. PMID: 28528078.
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    121. Cree-Green M, Cai N, Pyle L, Ringham B, Brown MS, Newcomer BR, Nadeau KJ, Dabelea D. Insulin Resistance in Youth Without Diabetes Is Not Related to Muscle Mitochondrial Dysfunction. J Clin Endocrinol Metab. 2017 05 01; 102(5):1652-1660. PMID: 28204552.
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    122. Maddux AB, Hiller TD, Overdier KH, Pyle LL, Douglas IS. Innate Immune Function and Organ Failure Recovery in Adults With Sepsis. J Intensive Care Med. 2019 Jun; 34(6):486-494. PMID: 28372498.
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    123. Bjornstad P, Cree-Green M, Baumgartner A, Coe G, Reyes YG, Schafer M, Pyle L, Regensteiner JG, Reusch JEB, Nadeau KJ. Leptin is associated with cardiopulmonary fitness independent of body-mass index and insulin sensitivity in adolescents with type 1 diabetes: a brief report from the EMERALD study. J Diabetes Complications. 2017 May; 31(5):850-853. PMID: 28336216.
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    124. Hurst AL, Olson D, Somme S, Child J, Pyle L, Ranade D, Stamatoiu A, Crombleholme T, Parker SK. Once-Daily Ceftriaxone Plus Metronidazole Versus Ertapenem and/or Cefoxitin for Pediatric Appendicitis. J Pediatric Infect Dis Soc. 2017 Mar 01; 6(1):57-64. PMID: 26703242.
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    125. Stewart CL, Acker SN, Pyle L, Smith DS, Bensard DD, Moulton SL. Mapping pediatric injuries to target prevention, education, and outreach. J Pediatr Surg. 2017 Aug; 52(8):1287-1291. PMID: 28073490.
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    126. Bjornstad P, Johnson RJ, Snell-Bergeon JK, Pyle L, Davis A, Foster N, Cherney DZ, Maahs DM. Albuminuria is associated with greater copeptin concentrations in men with type 1 diabetes: A brief report from the T1D exchange Biobank. J Diabetes Complications. 2017 Feb; 31(2):387-389. PMID: 27979439.
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    127. Forlenza GP, Pyle LL, Maahs DM, Dunn TC. Ambulatory glucose profile analysis of the juvenile diabetes research foundation continuous glucose monitoring dataset-Applications to the pediatric diabetes population. Pediatr Diabetes. 2017 Nov; 18(7):622-628. PMID: 27878929.
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    128. Chan CL, Pyle L, Kelsey MM, Newnes L, Baumgartner A, Zeitler PS, Nadeau KJ. Alternate glycemic markers reflect glycemic variability in continuous glucose monitoring in youth with prediabetes and type 2 diabetes. Pediatr Diabetes. 2017 Nov; 18(7):629-636. PMID: 27873436.
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    129. Milan M, Jhajj S, Stewart C, Pyle L, Moulton S. Helmet use and injury severity among pediatric skiers and snowboarders in Colorado. J Pediatr Surg. 2017 Feb; 52(2):349-353. PMID: 27876383.
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    130. Cree-Green M, Bergman BC, Coe GV, Newnes L, Baumgartner AD, Bacon S, Sherzinger A, Pyle L, Nadeau KJ. Hepatic Steatosis is Common in Adolescents with Obesity and PCOS and Relates to De Novo Lipogenesis but not Insulin Resistance. Obesity (Silver Spring). 2016 11; 24(11):2399-2406. PMID: 27804265.
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    131. Cree-Green M, Gupta A, Coe GV, Baumgartner AD, Pyle L, Reusch JE, Brown MS, Newcomer BR, Nadeau KJ. Insulin resistance in type 2 diabetes youth relates to serum free fatty acids and muscle mitochondrial dysfunction. J Diabetes Complications. 2017 01; 31(1):141-148. PMID: 27839922.
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    132. Mullin BC, Pyle L, Haraden D, Riederer J, Brim N, Kaplan D, Novins D. A Preliminary Multimethod Comparison of Sleep Among Adolescents With and Without Generalized Anxiety Disorder. J Clin Child Adolesc Psychol. 2017 Mar-Apr; 46(2):198-210. PMID: 27736237.
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    133. Baldelli L, Flitter B, Pyle L, Maahs DM, Klingensmith G, Slover R, Alonso GT. A survey of youth with new onset type 1 diabetes: Opportunities to reduce diabetic ketoacidosis. Pediatr Diabetes. 2017 Nov; 18(7):547-552. PMID: 27726268.
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    134. Davis S, Lahlou N, Bardsley M, Temple MC, Kowal K, Pyle L, Zeitler P, Ross J. Gonadal function is associated with cardiometabolic health in pre-pubertal boys with Klinefelter syndrome. Andrology. 2016 11; 4(6):1169-1177. PMID: 27637014.
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    135. Ohman-Hanson RA, Cree-Green M, Kelsey MM, Bessesen DH, Sharp TA, Pyle L, Pereira RI, Nadeau KJ. Ethnic and Sex Differences in Adiponectin: From Childhood to Adulthood. J Clin Endocrinol Metab. 2016 12; 101(12):4808-4815. PMID: 27603898.
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    136. Chan CL, Pyle L, Morehead R, Baumgartner A, Cree-Green M, Nadeau KJ. The role of glycemia in insulin resistance in youth with type 1 and type 2 diabetes. Pediatr Diabetes. 2017 Sep; 18(6):470-477. PMID: 27503277.
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    137. Bacha F, Gidding SS, Pyle L, Levitt Katz L, Kriska A, Nadeau KJ, Lima JAC. Relationship of Cardiac Structure and Function to Cardiorespiratory Fitness and Lean Body Mass in Adolescents and Young Adults with Type 2 Diabetes. J Pediatr. 2016 10; 177:159-166.e1. PMID: 27499218.
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    138. Fouts A, Pyle L, Yu L, Miao D, Michels A, Krischer J, Sosenko J, Gottlieb P, Steck AK. Do Electrochemiluminescence Assays Improve Prediction of Time to Type 1 Diabetes in Autoantibody-Positive TrialNet Subjects? Diabetes Care. 2016 Oct; 39(10):1738-44. PMID: 27456836.
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    139. Bjornstad P, Pyle L, Kinney GL, Rewers M, Johnson RJ, Maahs DM, Snell-Bergeon JK. Adiponectin is associated with early diabetic kidney disease in adults with type 1 diabetes: A Coronary Artery Calcification in Type 1 Diabetes (CACTI) Study. J Diabetes Complications. 2017 Feb; 31(2):369-374. PMID: 27368123.
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    140. Murphy JL, Fenn N, Pyle L, Heizer H, Hughes S, Nomura Y, Child J, Parker SK. Adverse Events in Pediatric Patients Receiving Long-term Oral and Intravenous Antibiotics. Hosp Pediatr. 2016 Jun; 6(6):330-8. PMID: 27220835.
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    141. Karlin AW, Ly TT, Pyle L, Forlenza GP, Messer L, Wadwa RP, DeSalvo DJ, Payne SL, Hanes S, Clinton P, Maahs DM, Buckingham B. Duration of Infusion Set Survival in Lipohypertrophy Versus Nonlipohypertrophied Tissue in Patients with Type 1 Diabetes. Diabetes Technol Ther. 2016 07; 18(7):429-35. PMID: 27227290.
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    142. Bjornstad P, Truong U, Pyle L, Dorosz JL, Cree-Green M, Baumgartner A, Coe G, Regensteiner JG, Reusch JE, Nadeau KJ. Youth with type 1 diabetes have worse strain and less pronounced sex differences in early echocardiographic markers of diabetic cardiomyopathy compared to their normoglycemic peers: A RESistance to InSulin in Type 1 ANd Type 2 diabetes (RESISTANT) Study. J Diabetes Complications. 2016 08; 30(6):1103-10. PMID: 27133451.
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    143. Bjornstad P, Truong U, Dorosz JL, Cree-Green M, Baumgartner A, Coe G, Pyle L, Regensteiner JG, Reusch JE, Nadeau KJ. Cardiopulmonary Dysfunction and Adiponectin in Adolescents With Type 2 Diabetes. J Am Heart Assoc. 2016 Mar 18; 5(3):e002804. PMID: 26994128.
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    144. Ljunggren P, Maahs DM, Johansson P, Ludvigsson J, Pyle L, Sippl R, Wadwa RP, Snell-Bergeon J. Reduced brachial artery distensibility in patients with type 1 diabetes. J Diabetes Complications. 2016 07; 30(5):893-7. PMID: 27056753.
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    145. Triolo TM, Maahs DM, Pyle L, Slover R, Buckingham B, Cheng P, DiMeglio LA, Bremer AA, Weinzimer SA, Chase HP. Effects of Frequency of Sensor-Augmented Pump Use on HbA1c and C-Peptide Levels in the First Year of Type 1 Diabetes. Diabetes Care. 2016 04; 39(4):e61-2. PMID: 26895885.
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    146. Bjornstad P, Maahs DM, Duca LM, Pyle L, Rewers M, Johnson RJ, Snell-Bergeon JK. Estimated insulin sensitivity predicts incident micro- and macrovascular complications in adults with type 1 diabetes over 6 years: the coronary artery calcification in type 1 diabetes study. J Diabetes Complications. 2016 May-Jun; 30(4):586-90. PMID: 26936306.
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    147. Pyle L, Bergman BC, Nadeau KJ, Cree-Green M. Modeling changes in glucose and glycerol rates of appearance when true basal rates of appearance cannot be readily determined. Am J Physiol Endocrinol Metab. 2016 Mar 01; 310(5):E323-31. PMID: 26714848.
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    148. Bjornstad P, Roncal C, Milagres T, Pyle L, Lanaspa MA, Bishop FK, Snell-Bergeon JK, Johnson RJ, Wadwa RP, Maahs DM. Hyperfiltration and uricosuria in adolescents with type 1 diabetes. Pediatr Nephrol. 2016 May; 31(5):787-93. PMID: 26701836.
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    149. Klingensmith GJ, Pyle L, Nadeau KJ, Barbour LA, Goland RS, Willi SM, Linder B, White NH. Pregnancy Outcomes in Youth With Type 2 Diabetes: The TODAY Study Experience. Diabetes Care. 2016 Jan; 39(1):122-9. PMID: 26628417.
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    150. Stewart CL, Acker SN, Pyle LL, Kulungowski A, Cadnapaphornchai M, Bruny JL, Karrer F. Factors associated with peritoneal dialysis catheter complications in children. J Pediatr Surg. 2016 Jan; 51(1):159-62. PMID: 26572851.
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    151. Maahs DM, DeSalvo D, Pyle L, Ly T, Messer L, Clinton P, Westfall E, Wadwa RP, Buckingham B. Effect of acetaminophen on CGM glucose in an outpatient setting. Diabetes Care. 2015 Oct; 38(10):e158-9. PMID: 26269199.
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    152. Bjornstad P, Eckel RH, Pyle L, Rewers M, Maahs DM, Snell-Bergeon JK. Relation of Combined Non-High-Density Lipoprotein Cholesterol and Apolipoprotein B With Atherosclerosis in Adults With Type 1 Diabetes Mellitus. Am J Cardiol. 2015 Oct 01; 116(7):1057-62. PMID: 26251001.
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    153. Cree-Green M, Maahs DM, Ferland A, Hokanson JE, Wang H, Pyle L, Kinney GL, King M, Eckel RH, Nadeau KJ. Lipoprotein subfraction cholesterol distribution is more atherogenic in insulin resistant adolescents with type 1 diabetes. Pediatr Diabetes. 2016 06; 17(4):257-65. PMID: 26080650.
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    154. Bjornstad P, Cherney DZ, Snell-Bergeon JK, Pyle L, Rewers M, Johnson RJ, Maahs DM. Rapid GFR decline is associated with renal hyperfiltration and impaired GFR in adults with Type 1 diabetes. Nephrol Dial Transplant. 2015 Oct; 30(10):1706-11. PMID: 26050268.
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    155. Cree-Green M, Newcomer BR, Coe G, Newnes L, Baumgartner A, Brown MS, Pyle L, Reusch JE, Nadeau KJ. Peripheral insulin resistance in obese girls with hyperandrogenism is related to oxidative phosphorylation and elevated serum free fatty acids. Am J Physiol Endocrinol Metab. 2015 May 01; 308(9):E726-33. PMID: 25714677.
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    156. Kelsey MM, Geffner ME, Guandalini C, Pyle L, Tamborlane WV, Zeitler PS, White NH. Presentation and effectiveness of early treatment of type 2 diabetes in youth: lessons from the TODAY study. Pediatr Diabetes. 2016 May; 17(3):212-21. PMID: 25690268.
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    157. Chan CL, Pyle L, Kelsey M, Newnes L, Zeitler PS, Nadeau KJ. Screening for type 2 diabetes and prediabetes in obese youth: evaluating alternate markers of glycemia - 1,5-anhydroglucitol, fructosamine, and glycated albumin. Pediatr Diabetes. 2016 May; 17(3):206-11. PMID: 25652226.
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    158. Bjornstad P, Pyle L, Nguyen N, Snell-Bergeon JK, Bishop FK, Wadwa RP, Maahs DM. Achieving International Society for Pediatric and Adolescent Diabetes and American Diabetes Association clinical guidelines offers cardiorenal protection for youth with type 1 diabetes. Pediatr Diabetes. 2015 Feb; 16(1):22-30. PMID: 25604668.
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    159. Stewart CL, Mulligan J, Grudic GZ, Pyle L, Moulton SL. A noninvasive computational method for fluid resuscitation monitoring in pediatric burns: a preliminary report. J Burn Care Res. 2015 Jan-Feb; 36(1):145-50. PMID: 25383980.
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    160. Bjornstad P, Nguyen N, Reinick C, Maahs DM, Bishop FK, Clements SA, Snell-Bergeon JK, Lieberman R, Pyle L, Daniels SR, Paul Wadwa R. Association of apolipoprotein B, LDL-C and vascular stiffness in adolescents with type 1 diabetes. Acta Diabetol. 2015 Jun; 52(3):611-9. PMID: 25539881.
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    161. Chan CL, Pyle L, Newnes L, Nadeau KJ, Zeitler PS, Kelsey MM. Continuous glucose monitoring and its relationship to hemoglobin A1c and oral glucose tolerance testing in obese and prediabetic youth. J Clin Endocrinol Metab. 2015 Mar; 100(3):902-10. PMID: 25532041.
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    162. Bjornstad P, Cree-Green M, Baumgartner A, Maahs DM, Cherney DZ, Pyle L, Regensteiner JG, Reusch JE, Nadeau KJ. Renal function is associated with peak exercise capacity in adolescents with type 1 diabetes. Diabetes Care. 2015 Jan; 38(1):126-31. PMID: 25414156.
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    163. Stewart CL, Metzger RR, Pyle L, Darmofal J, Scaife E, Moulton SL. Helicopter versus ground emergency medical services for the transportation of traumatically injured children. J Pediatr Surg. 2015 Feb; 50(2):347-52. PMID: 25638635.
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    164. Bjornstad P, Maahs DM, Wadwa RP, Pyle L, Rewers M, Eckel RH, Snell-Bergeon JK. Plasma triglycerides predict incident albuminuria and progression of coronary artery calcification in adults with type 1 diabetes: the Coronary Artery Calcification in Type 1 Diabetes Study. J Clin Lipidol. 2014 Nov-Dec; 8(6):576-583. PMID: 25499940.
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    165. Cree-Green M, Newcomer BR, Brown MS, Baumgartner AD, Bergman B, Drew B, Regensteiner JG, Pyle L, Reusch JE, Nadeau KJ. Delayed skeletal muscle mitochondrial ADP recovery in youth with type 1 diabetes relates to muscle insulin resistance. Diabetes. 2015 Feb; 64(2):383-92. PMID: 25157095.
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    166. Bjornstad P, Maahs DM, Cherney DZ, Cree-Green M, West A, Pyle L, Nadeau KJ. Insulin sensitivity is an important determinant of renal health in adolescents with type 2 diabetes. Diabetes Care. 2014 Nov; 37(11):3033-9. PMID: 25071077.
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    167. Bjornstad P, Maahs DM, Rivard CJ, Pyle L, Rewers M, Johnson RJ, Snell-Bergeon JK. Serum uric acid predicts vascular complications in adults with type 1 diabetes: the coronary artery calcification in type 1 diabetes study. Acta Diabetol. 2014 Oct; 51(5):783-91. PMID: 24929955.
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    168. Maahs DM, Bushman L, Kerr B, Ellis SL, Pyle L, McFann K, Bouffard A, Bishop FK, Nguyen N, Anderson PL. A practical method to measure GFR in people with type 1 diabetes. J Diabetes Complications. 2014 Sep-Oct; 28(5):667-73. PMID: 25027389.
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    169. Bjornstad P, McQueen RB, Snell-Bergeon JK, Cherney D, Pyle L, Perkins B, Rewers M, Maahs DM. Fasting blood glucose--a missing variable for GFR-estimation in type 1 diabetes? PLoS One. 2014; 9(4):e96264. PMID: 24781861.
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    170. Lindquist KA, Chow K, West A, Pyle L, Isbell TS, Cree-Green M, Nadeau KJ. The StatStrip glucose monitor is suitable for use during hyperinsulinemic euglycemic clamps in a pediatric population. Diabetes Technol Ther. 2014 May; 16(5):298-302. PMID: 24471560.
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    171. Maahs DM, Chase HP, Westfall E, Slover R, Huang S, Shin JJ, Kaufman FR, Pyle L, Snell-Bergeon JK. The effects of lowering nighttime and breakfast glucose levels with sensor-augmented pump therapy on hemoglobin A1c levels in type 1 diabetes. Diabetes Technol Ther. 2014 May; 16(5):284-91. PMID: 24450776.
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    172. Levitt Katz L, Gidding SS, Bacha F, Hirst K, McKay S, Pyle L, Lima JA. Alterations in left ventricular, left atrial, and right ventricular structure and function to cardiovascular risk factors in adolescents with type 2 diabetes participating in the TODAY clinical trial. Pediatr Diabetes. 2015 Feb; 16(1):39-47. PMID: 24450390.
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    173. Zeitler P, Hirst K, Pyle L, Linder B, Copeland K, Arslanian S, Cuttler L, Nathan DM, Tollefsen S, Wilfley D, Kaufman F. A clinical trial to maintain glycemic control in youth with type 2 diabetes. N Engl J Med. 2012 Jun 14; 366(24):2247-56. PMID: 22540912.
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    174. Bacha F, Pyle L, Nadeau K, Cuttler L, Goland R, Haymond M, Levitsky L, Lynch J, Weinstock RS, White NH, Caprio S, Arslanian S. Determinants of glycemic control in youth with type 2 diabetes at randomization in the TODAY study. Pediatr Diabetes. 2012 Aug; 13(5):376-83. PMID: 22332798.
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    175. Copeland KC, Zeitler P, Geffner M, Guandalini C, Higgins J, Hirst K, Kaufman FR, Linder B, Marcovina S, McGuigan P, Pyle L, Tamborlane W, Willi S. Characteristics of adolescents and youth with recent-onset type 2 diabetes: the TODAY cohort at baseline. J Clin Endocrinol Metab. 2011 Jan; 96(1):159-67. PMID: 20962021.
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    176. Klingensmith GJ, Pyle L, Arslanian S, Copeland KC, Cuttler L, Kaufman F, Laffel L, Marcovina S, Tollefsen SE, Weinstock RS, Linder B. The presence of GAD and IA-2 antibodies in youth with a type 2 diabetes phenotype: results from the TODAY study. Diabetes Care. 2010 Sep; 33(9):1970-5. PMID: 20519658.
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    177. Goldfine AB, Fonseca V, Jablonski KA, Pyle L, Staten MA, Shoelson SE. The effects of salsalate on glycemic control in patients with type 2 diabetes: a randomized trial. Ann Intern Med. 2010 Mar 16; 152(6):346-57. PMID: 20231565.
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    178. Jago R, McMurray RG, Bassin S, Pyle L, Bruecker S, Jakicic JM, Moe E, Murray T, Volpe SL. Modifying middle school physical education: piloting strategies to increase physical activity. Pediatr Exerc Sci. 2009 May; 21(2):171-85. PMID: 19556623.
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    179. Grey M, Schreiner B, Pyle L. Development of a diabetes education program for youth with type 2 diabetes. Diabetes Educ. 2009 Jan-Feb; 35(1):108-16. PMID: 19244566.
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