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Randall J Cohrs

InstitutionUniversity of Colorado Denver - Anschutz Medical Campus

    Collapse Research 
    Collapse research activities and funding
    R01AI030462     (COHRS, RANDALL J.)Apr 1, 1990 - Mar 31, 1993
    Role: Principal Investigator

    R01NS082228     (COHRS, RANDALL J.)Feb 15, 2013 - Jan 31, 2018
    Prevention of VZV Reactivation
    Role: Principal Investigator

    R13AG046051     (COHRS, RANDALL J)Apr 15, 2014 - Mar 31, 2020
    Annual Symposium of the Colorado Alphaherpesvirus Latency Society
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Rovnak J, Clair LAS, Krieger K, Lian E, Perera R, Cohrs RJ. The 18th Rocky Mountain Virology Association Meeting. Viruses. 2018 Dec 21; 11(1). PMID: 30577629.
      View in: PubMed
    2. Baird NL, Depledge DP, Cohrs RJ. 2018 Colorado Alphaherpesvirus Latency Society Symposium. J Neurovirol. 2018 Dec; 24(6):797-812. PMID: 30414047.
      View in: PubMed
    3. Bubak AN, Como CN, Blackmon AM, Frietze S, Mescher T, Jones D, Cohrs RJ, Paucek P, Baird NL, Nagel MA. Varicella Zoster Virus Induces Nuclear Translocation of the Neurokinin-1 Receptor, Promoting Lamellipodia Formation and Viral Spread in Spinal Astrocytes. J Infect Dis. 2018 Sep 08; 218(8):1324-1335. PMID: 29788447.
      View in: PubMed
    4. Como CN, Pearce CM, Cohrs RJ, Baird NL. Interleukin-6 and type 1 interferons inhibit varicella zoster virus replication in human neurons. Virology. 2018 09; 522:13-18. PMID: 29979960.
      View in: PubMed
    5. Depledge DP, Ouwendijk WJD, Sadaoka T, Braspenning SE, Mori Y, Cohrs RJ, Verjans GMGM, Breuer J. A spliced latency-associated VZV transcript maps antisense to the viral transactivator gene 61. Nat Commun. 2018 03 21; 9(1):1167. PMID: 29563516.
      View in: PubMed
    6. Rovnak J, Perera R, Hopken MW, Read J, Waller DM, Cohrs RJ. The 17th Rocky Mountain Virology Association Meeting. Viruses. 2017 11 08; 9(11). PMID: 29117106.
      View in: PubMed
    7. Baird NL, Cohrs RJ. Erratum to: 2017 Colorado alphaherpesvirus latency society symposium. J Neurovirol. 2017 Oct; 23(5):793. PMID: 28963639.
      View in: PubMed
    8. Cohrs RJ, Lee KS, Beach A, Sanford B, Baird NL, Como C, Graybill C, Jones D, Tekeste E, Ballard M, Chen X, Yalacki D, Frietze S, Jones K, Lenac Rovis T, Jonjic S, Haas J, Gilden D. Targeted Genome Sequencing Reveals Varicella-Zoster Virus Open Reading Frame 12 Deletion. J Virol. 2017 10 15; 91(20). PMID: 28747504.
      View in: PubMed
    9. Baird NL, Cohrs RJ. 2017 Colorado alphaherpesvirus latency society symposium. J Neurovirol. 2017 08; 23(4):642-655. PMID: 28786028.
      View in: PubMed
    10. Owens GP, Nagel MA, Mahalingam R, Cohrs RJ. Donald H. Gilden, M.D. J Neuroimmunol. 2017 07 15; 308:2-5. PMID: 28087078.
      View in: PubMed
    11. Cohrs RJ, Badani H, Baird NL, White TM, Sanford B, Gilden D. Induction of varicella zoster virus DNA replication in dissociated human trigeminal ganglia. J Neurovirol. 2017 02; 23(1):152-157. PMID: 27683235.
      View in: PubMed
    12. Gilden D, Grose C, White T, Nagae L, Hendricks RL, Cohrs RJ, Nagel MA. Successful antiviral treatment after 6years of chronic progressive neurological disease attributed to VZV brain infection. J Neurol Sci. 2016 Sep 15; 368:240-2. PMID: 27538641; PMCID: PMC4996351 [Available on 09/15/17].
    13. Cohrs RJ, Gilden D. 2016 Colorado alphaherpesvirus latency society symposium. J Neurovirol. 2016 10; 22(5):703-714. PMID: 27405986.
      View in: PubMed
    14. Biswas K, Chatterjee D, Addya S, Khan RS, Kenyon LC, Choe A, Cohrs RJ, Shindler KS, Das Sarma J. Demyelinating strain of mouse hepatitis virus infection bridging innate and adaptive immune response in the induction of demyelination. Clin Immunol. 2016 09; 170:9-19. PMID: 27394164.
      View in: PubMed
    15. Keller AC, Badani H, McClatchey PM, Baird NL, Bowlin JL, Bouchard R, Perng GC, Reusch JE, Kaufer BB, Gilden D, Shahzad A, Kennedy PG, Cohrs RJ. Varicella zoster virus infection of human fetal lung cells alters mitochondrial morphology. J Neurovirol. 2016 10; 22(5):674-682. PMID: 27245593.
      View in: PubMed
    16. Cohrs RJ, Badani H, Bos N, Scianna C, Hoskins I, Baird NL, Gilden D. Alphaherpesvirus DNA replication in dissociated human trigeminal ganglia. J Neurovirol. 2016 10; 22(5):688-694. PMID: 27173396.
      View in: PubMed
    17. Gilden D, Nagel M, Cohrs R, Mahalingam R, Baird N. Varicella Zoster Virus in the Nervous System. F1000Res. 2015; 4. PMID: 26918131; PMCID: PMC4754002.
    18. Henderson HH, Timberlake KB, Austin ZA, Badani H, Sanford B, Tremblay K, Baird NL, Jones K, Rovnak J, Frietze S, Gilden D, Cohrs RJ. Occupancy of RNA Polymerase II Phosphorylated on Serine 5 (RNAP S5P) and RNAP S2P on Varicella-Zoster Virus Genes 9, 51, and 66 Is Independent of Transcript Abundance and Polymerase Location within the Gene. J Virol. 2016 02 01; 90(3):1231-43. PMID: 26559844.
      View in: PubMed
    19. Cohrs RJ, Gilden D. 2015 Colorado Alphaherpesvirus Latency Society Symposium. J Neurovirol. 2015 Dec; 21(6):706-16. PMID: 26506840.
      View in: PubMed
    20. Gershon AA, Breuer J, Cohen JI, Cohrs RJ, Gershon MD, Gilden D, Grose C, Hambleton S, Kennedy PG, Oxman MN, Seward JF, Yamanishi K. Varicella zoster virus infection. Nat Rev Dis Primers. 2015 07 02; 1:15016. PMID: 27188665.
      View in: PubMed
    21. Goodwin TJ, McCarthy M, Cohrs RJ, Kaufer BB. 3D tissue-like assemblies: A novel approach to investigate virus-cell interactions. Methods. 2015 Nov 15; 90:76-84. PMID: 25986169.
      View in: PubMed
    22. Baird NL, Bowlin JL, Hotz TJ, Cohrs RJ, Gilden D. Interferon Gamma Prolongs Survival of Varicella-Zoster Virus-Infected Human Neurons In Vitro. J Virol. 2015 Jul; 89(14):7425-7. PMID: 25948748; PMCID: PMC4473560.
    23. Kennedy PG, Rovnak J, Badani H, Cohrs RJ. A comparison of herpes simplex virus type 1 and varicella-zoster virus latency and reactivation. J Gen Virol. 2015 Jul; 96(Pt 7):1581-602. PMID: 25794504; PMCID: PMC4635449.
    24. Shahzad A, Gilden D, Cohrs RJ. Translational medicine and varicella zoster virus: need for disease modeling. New Horiz Transl Med. 2015 Mar 01; 2(3):89-91. PMID: 26086038.
      View in: PubMed
    25. Gilden D, White T, Khmeleva N, Heintzman A, Choe A, Boyer PJ, Grose C, Carpenter JE, Rempel A, Bos N, Kandasamy B, Lear-Kaul K, Holmes DB, Bennett JL, Cohrs RJ, Mahalingam R, Mandava N, Eberhart CG, Bockelman B, Poppiti RJ, Tamhankar MA, Fogt F, Amato M, Wood E, Durairaj V, Rasmussen S, Petursdottir V, Pollak L, Mendlovic S, Chatelain D, Keyvani K, Brueck W, Nagel MA. Prevalence and distribution of VZV in temporal arteries of patients with giant cell arteritis. Neurology. 2015 May 12; 84(19):1948-55. PMID: 25695965; PMCID: PMC4433460.
    26. Cohrs RJ, Gilden D. 2014 Colorado alphaherpesvirus latency symposium. J Neurovirol. 2014 Dec; 20(6):644-56. PMID: 25371285.
      View in: PubMed
    27. Chatterjee D, Addya S, Khan RS, Kenyon LC, Choe A, Cohrs RJ, Shindler KS, Sarma JD. Mouse hepatitis virus infection upregulates genes involved in innate immune responses. PLoS One. 2014; 9(10):e111351. PMID: 25360880; PMCID: PMC4216085.
    28. Pollak L, Mehta SK, Pierson DL, Sacagiu T, Avneri Kalmanovich S, Cohrs RJ. Varicella-zoster DNA in saliva of patients with meningoencephalitis: a preliminary study. Acta Neurol Scand. 2015 Jun; 131(6):417-21. PMID: 25314141.
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    29. Baird NL, Bowlin JL, Yu X, Jonjic S, Haas J, Cohrs RJ, Gilden D. Varicella zoster virus DNA does not accumulate in infected human neurons. Virology. 2014 Jun; 458-459:1-3. PMID: 24928033; PMCID: PMC4108071.
    30. Baird NL, Bowlin JL, Cohrs RJ, Gilden D, Jones KL. Comparison of varicella-zoster virus RNA sequences in human neurons and fibroblasts. J Virol. 2014 May; 88(10):5877-80. PMID: 24600007; PMCID: PMC4019124.
    31. Sabry A, Hauk PJ, Jing H, Su HC, Stence NV, Mirsky DM, Nagel MA, Abbott JK, Dragone LL, Armstrong-Wells J, Curtis DJ, Cohrs R, Schmid DS, Gilden D, Gelfand EW. Vaccine strain varicella-zoster virus-induced central nervous system vasculopathy as the presenting feature of DOCK8 deficiency. J Allergy Clin Immunol. 2014 Apr; 133(4):1225-1227. PMID: 24418481; PMCID: PMC3972264.
    32. Gilden D, Nagel MA, Cohrs RJ. Varicella-zoster. Handb Clin Neurol. 2014; 123:265-83. PMID: 25015490.
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    33. Birlea M, Nagel MA, Khmeleva N, Choe A, Kleinschmidt-Demasters B, Hevner R, Boyer P, Lear-Kaul KC, Bos N, Wellish M, Cohrs RJ, Gilden D. Varicella-zoster virus trigeminal ganglioneuritis without rash. Neurology. 2014 Jan 07; 82(1):90-2. PMID: 24285619; PMCID: PMC3873618.
    34. Birlea M, Cohrs RJ, Bos N, Mehta SK, Pierson DL, Gilden D. Search for varicella zoster virus DNA in saliva of healthy individuals aged 20-59 years. J Med Virol. 2014 Feb; 86(2):360-2. PMID: 24338812; PMCID: PMC3869028.
    35. Cohrs RJ, Gilden D. 2013 Colorado alphaherpesvirus latency symposium. J Neurovirol. 2013 Dec; 19(6):610-7. PMID: 24092643.
      View in: PubMed
    36. Baird NL, Yu X, Cohrs RJ, Gilden D. Varicella zoster virus (VZV)-human neuron interaction. Viruses. 2013 Sep 04; 5(9):2106-15. PMID: 24008377; PMCID: PMC3798892.
    37. Gilden D, Nagel MA, Cohrs RJ, Mahalingam R. The variegate neurological manifestations of varicella zoster virus infection. Curr Neurol Neurosci Rep. 2013 Sep; 13(9):374. PMID: 23884722; PMCID: PMC4051361.
    38. Mueller NH, Gilden D, Cohrs RJ. Varicella-zoster virus open reading frame 48 encodes an active nuclease. J Virol. 2013 Nov; 87(21):11936-8. PMID: 23966396; PMCID: PMC3807315.
    39. Goodwin TJ, McCarthy M, Osterrieder N, Cohrs RJ, Kaufer BB. Three-dimensional normal human neural progenitor tissue-like assemblies: a model of persistent varicella-zoster virus infection. PLoS Pathog. 2013; 9(8):e1003512. PMID: 23935496; PMCID: PMC3731237.
    40. Grose C, Yu X, Cohrs RJ, Carpenter JE, Bowlin JL, Gilden D. Aberrant virion assembly and limited glycoprotein C production in varicella-zoster virus-infected neurons. J Virol. 2013 Sep; 87(17):9643-8. PMID: 23804641; PMCID: PMC3754126.
    41. Nagel MA, Choe A, Gilden D, Traina-Dorge V, Cohrs RJ, Mahalingam R. GeXPS multiplex PCR analysis of the simian varicella virus transcriptome in productively infected cells in culture and acutely infected ganglia. J Virol Methods. 2013 Oct; 193(1):151-8. PMID: 23769859; PMCID: PMC3782101.
    42. Mehta SK, Tyring SK, Cohrs RJ, Gilden D, Feiveson AH, Lechler KJ, Pierson DL. Rapid and sensitive detection of varicella zoster virus in saliva of patients with herpes zoster. J Virol Methods. 2013 Oct; 193(1):128-30. PMID: 23747545; PMCID: PMC3735804.
    43. Yu X, Seitz S, Pointon T, Bowlin JL, Cohrs RJ, Jonjic S, Haas J, Wellish M, Gilden D. Varicella zoster virus infection of highly pure terminally differentiated human neurons. J Neurovirol. 2013 Feb; 19(1):75-81. PMID: 23233078; PMCID: PMC3568217.
    44. Birlea M, Owens GP, Eshleman EM, Ritchie A, Traktinskiy I, Bos N, Seitz S, Azarkh Y, Mahalingam R, Gilden D, Cohrs RJ. Human anti-varicella-zoster virus (VZV) recombinant monoclonal antibody produced after Zostavax immunization recognizes the gH/gL complex and neutralizes VZV infection. J Virol. 2013 Jan; 87(1):415-21. PMID: 23077312; PMCID: PMC3536365.
    45. Cohrs RJ, Gilden D. 2012 Colorado alphaherpesvirus latency symposium. J Neurovirol. 2012 Dec; 18(6):541-8. PMID: 22972600.
      View in: PubMed
    46. Mehta SK, Gilden D, Crucian BE, Sams CF, Cohrs RJ, Pierson DL. A Case Report: PCR-Assisted Diagnosis of Varicella in an Adult. Open J Med Microbiol. 2012 Sep; 2(3). PMID: 24409401.
      View in: PubMed
    47. Silver B, Nagel MA, Mahalingam R, Cohrs R, Schmid DS, Gilden D. Varicella zoster virus vasculopathy: a treatable form of rapidly progressive multi-infarct dementia after 2 years' duration. J Neurol Sci. 2012 Dec 15; 323(1-2):245-7. PMID: 22935406; PMCID: PMC3483445.
    48. Wolf J, Nagel MA, Mahalingam R, Cohrs RJ, Schmid DS, Gilden D. Chronic active varicella zoster virus infection. Neurology. 2012 Aug 21; 79(8):828-9. PMID: 22875096; PMCID: PMC3421154.
    49. Azarkh Y, Bos N, Gilden D, Cohrs RJ. Human trigeminal ganglionic explants as a model to study alphaherpesvirus reactivation. J Neurovirol. 2012 Dec; 18(6):456-61. PMID: 22851387; PMCID: PMC3584453.
    50. Ouwendijk WJ, Choe A, Nagel MA, Gilden D, Osterhaus AD, Cohrs RJ, Verjans GM. Restricted varicella-zoster virus transcription in human trigeminal ganglia obtained soon after death. J Virol. 2012 Sep; 86(18):10203-6. PMID: 22740396; PMCID: PMC3446590.
    51. Mueller NH, Bos NL, Seitz S, Wellish M, Mahalingam R, Gilden D, Cohrs RJ. Recombinant monoclonal antibody recognizes a unique epitope on varicella-zoster virus immediate-early 63 protein. J Virol. 2012 Jun; 86(11):6345-9. PMID: 22438547; PMCID: PMC3372203.
    52. Gilden D, Nagel MA, Cohrs RJ. Persistence of varicella zoster virus DNA in saliva after herpes zoster. J Infect Dis. 2012 Apr 01; 205(7):1178; author reply 1178-9. PMID: 22351945; PMCID: PMC3295602.
    53. Cohrs R, Gilden D. Alphaherpesvirus latency. J Neurovirol. 2011 Dec; 17(6):509-11. PMID: 22231564.
      View in: PubMed
    54. Shahzad A, Cohrs RJ. In vitro antiviral activity of honey against varicella zoster virus (VZV): A translational medicine study for potential remedy for shingles. Transl Biomed. 2012; 3(2). PMID: 22822475.
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    55. Tsai J, Cohrs RJ, Nagel MA, Mahalingam R, Schmid DS, Choe A, Gilden D. Reactivation of type 1 herpes simplex virus and varicella zoster virus in an immunosuppressed patient with acute peripheral facial weakness. J Neurol Sci. 2012 Feb 15; 313(1-2):193-5. PMID: 21924743; PMCID: PMC3243805.
    56. Nagel MA, Choe A, Cohrs RJ, Traktinskiy I, Sorensen K, Mehta SK, Pierson DL, Tyring SK, Haitz K, Digiorgio C, Lapolla W, Gilden D. Persistence of varicella zoster virus DNA in saliva after herpes zoster. J Infect Dis. 2011 Sep 15; 204(6):820-4. PMID: 21849278; PMCID: PMC3156921.
    57. Cohrs RJ, Gilden D. Colorado alphaherpesvirus latency symposium. J Neurovirol. 2011 Aug; 17(4):393-9. PMID: 21847669.
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    58. Gilden D, Mahalingam R, Nagel MA, Pugazhenthi S, Cohrs RJ. Review: The neurobiology of varicella zoster virus infection. Neuropathol Appl Neurobiol. 2011 Aug; 37(5):441-63. PMID: 21342215; PMCID: PMC3176736.
    59. Nagel MA, Traktinskiy I, Azarkh Y, Kleinschmidt-DeMasters B, Hedley-Whyte T, Russman A, VanEgmond EM, Stenmark K, Frid M, Mahalingam R, Wellish M, Choe A, Cordery-Cotter R, Cohrs RJ, Gilden D. Varicella zoster virus vasculopathy: analysis of virus-infected arteries. Neurology. 2011 Jul 26; 77(4):364-70. PMID: 21753174; PMCID: PMC3140801.
    60. Pierson DL, Mehta SK, Gilden D, Cohrs RJ, Nagel MA, Schmid DS, Tyring SK. Varicella zoster virus DNA at inoculation sites and in saliva after Zostavax immunization. J Infect Dis. 2011 Jun 01; 203(11):1542-5. PMID: 21592982; PMCID: PMC3096786.
    61. Pugazhenthi S, Nair S, Velmurugan K, Liang Q, Mahalingam R, Cohrs RJ, Nagel MA, Gilden D. Varicella-zoster virus infection of differentiated human neural stem cells. J Virol. 2011 Jul; 85(13):6678-86. PMID: 21525352; PMCID: PMC3126546.
    62. Azarkh Y, Dölken L, Nagel M, Gilden D, Cohrs RJ. Synthesis and decay of varicella zoster virus transcripts. J Neurovirol. 2011 Jun; 17(3):281-7. PMID: 21484478; PMCID: PMC3153418.
    63. Brazeau E, Wellish M, Kaufer BB, Tischer BK, Gray W, Zhou F, Osterrieder N, Hanlon T, Golive A, Hall T, Nair S, Owens GP, Mueller NH, Cohrs RJ, Pugazhenthi S, Gilden D, Mahalingam R. Simian varicella virus open reading frame 63/70 expression is required for efficient virus replication in culture. J Neurovirol. 2011 Jun; 17(3):274-80. PMID: 21479719; PMCID: PMC3204661.
    64. Salazar R, Russman AN, Nagel MA, Cohrs RJ, Mahalingam R, Schmid DS, Kleinschmidt-DeMasters BK, VanEgmond EM, Gilden D. Varicella zoster virus ischemic optic neuropathy and subclinical temporal artery involvement. Arch Neurol. 2011 Apr; 68(4):517-20. PMID: 21482932; PMCID: PMC3238137.
    65. Birlea M, Arendt G, Orhan E, Schmid DS, Bellini WJ, Schmidt C, Gilden D, Cohrs RJ. Subclinical reactivation of varicella zoster virus in all stages of HIV infection. J Neurol Sci. 2011 May 15; 304(1-2):22-4. PMID: 21419427; PMCID: PMC3176733.
    66. Eshleman E, Shahzad A, Cohrs RJ. Varicella zoster virus latency. Future Virol. 2011 Mar; 6(3):341-355. PMID: 21695042.
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    67. Blumenthal DT, Shacham-Shmueli E, Bokstein F, Schmid DS, Cohrs RJ, Nagel MA, Mahalingam R, Gilden D. Zoster sine herpete: virologic verification by detection of anti-VZV IgG antibody in CSF. Neurology. 2011 Feb 01; 76(5):484-5. PMID: 21282595; PMCID: PMC3034410.
    68. Nagel MA, Choe A, Traktinskiy I, Cordery-Cotter R, Gilden D, Cohrs RJ. Varicella-zoster virus transcriptome in latently infected human ganglia. J Virol. 2011 Mar; 85(5):2276-87. PMID: 21177814; PMCID: PMC3067783.
    69. Kennedy PG, Cohrs RJ. Varicella-zoster virus human ganglionic latency: a current summary. J Neurovirol. 2010 Nov; 16(6):411-8. PMID: 20874010.
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    70. Nagel MA, Mahalingam R, Cohrs RJ, Gilden D. Virus vasculopathy and stroke: an under-recognized cause and treatment target. Infect Disord Drug Targets. 2010 Apr; 10(2):105-11. PMID: 20166970; PMCID: PMC2909030.
    71. Haug A, Mahalingam R, Cohrs RJ, Schmid DS, Corboy JR, Gilden D. Recurrent polymorphonuclear pleocytosis with increased red blood cells caused by varicella zoster virus infection of the central nervous system: Case report and review of the literature. J Neurol Sci. 2010 May 15; 292(1-2):85-8. PMID: 20170926; PMCID: PMC2846975.
    72. Mueller NH, Walters MS, Marcus RA, Graf LL, Prenni J, Gilden D, Silverstein SJ, Cohrs RJ. Identification of phosphorylated residues on varicella-zoster virus immediate-early protein ORF63. J Gen Virol. 2010 May; 91(Pt 5):1133-7. PMID: 20089801; PMCID: PMC2888152.
    73. Azarkh Y, Gilden D, Cohrs RJ. Molecular characterization of varicella zoster virus in latently infected human ganglia: physical state and abundance of VZV DNA, Quantitation of viral transcripts and detection of VZV-specific proteins. Curr Top Microbiol Immunol. 2010; 342:229-41. PMID: 20186615; PMCID: PMC3016873.
    74. Gilden D, Cohrs RJ, Mahalingam R, Nagel MA. Neurological disease produced by varicella zoster virus reactivation without rash. Curr Top Microbiol Immunol. 2010; 342:243-53. PMID: 20186614; PMCID: PMC3076592.
    75. Mueller NH, Graf LL, Orlicky D, Gilden D, Cohrs RJ. Phosphorylation of the nuclear form of varicella-zoster virus immediate-early protein 63 by casein kinase II at serine 186. J Virol. 2009 Dec; 83(23):12094-100. PMID: 19759161; PMCID: PMC2786752.
    76. Umbach JL, Nagel MA, Cohrs RJ, Gilden DH, Cullen BR. Analysis of human alphaherpesvirus microRNA expression in latently infected human trigeminal ganglia. J Virol. 2009 Oct; 83(20):10677-83. PMID: 19656888; PMCID: PMC2753103.
    77. Gilden D, Cohrs RJ, Mahalingam R, Nagel MA. Varicella zoster virus vasculopathies: diverse clinical manifestations, laboratory features, pathogenesis, and treatment. Lancet Neurol. 2009 Aug; 8(8):731-40. PMID: 19608099; PMCID: PMC2814602.
    78. Burgoon MP, Cohrs RJ, Bennett JL, Anderson SW, Ritchie AM, Cepok S, Hemmer B, Gilden D, Owens GP. Varicella zoster virus is not a disease-relevant antigen in multiple sclerosis. Ann Neurol. 2009 Apr; 65(4):474-9. PMID: 19399839; PMCID: PMC2844106.
    79. Nagel MA, Gilden D, Shade T, Gao B, Cohrs RJ. Rapid and sensitive detection of 68 unique varicella zoster virus gene transcripts in five multiplex reverse transcription-polymerase chain reactions. J Virol Methods. 2009 Apr; 157(1):62-8. PMID: 19109999; PMCID: PMC2829835.
    80. Gilden D, Nagel MA, Mahalingam R, Mueller NH, Brazeau EA, Pugazhenthi S, Cohrs RJ. Clinical and molecular aspects of varicella zoster virus infection. Future Neurol. 2009 Jan 01; 4(1):103-117. PMID: 19946620.
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    81. Gilden D, Nagel MA, Ransohoff RM, Cohrs RJ, Mahalingam R, Tanabe JL. Recurrent varicella zoster virus myelopathy. J Neurol Sci. 2009 Jan 15; 276(1-2):196-8. PMID: 18945446; PMCID: PMC2828365.
    82. Mueller NH, Gilden DH, Cohrs RJ, Mahalingam R, Nagel MA. Varicella zoster virus infection: clinical features, molecular pathogenesis of disease, and latency. Neurol Clin. 2008 Aug; 26(3):675-97, viii. PMID: 18657721; PMCID: PMC2754837.
    83. Cohrs RJ, Mehta SK, Schmid DS, Gilden DH, Pierson DL. Asymptomatic reactivation and shed of infectious varicella zoster virus in astronauts. J Med Virol. 2008 Jun; 80(6):1116-22. PMID: 18428120; PMCID: PMC2938738.
    84. Nagel MA, Cohrs RJ, Mahalingam R, Wellish MC, Forghani B, Schiller A, Safdieh JE, Kamenkovich E, Ostrow LW, Levy M, Greenberg B, Russman AN, Katzan I, Gardner CJ, Häusler M, Nau R, Saraya T, Wada H, Goto H, de Martino M, Ueno M, Brown WD, Terborg C, Gilden DH. The varicella zoster virus vasculopathies: clinical, CSF, imaging, and virologic features. Neurology. 2008 Mar 11; 70(11):853-60. PMID: 18332343; PMCID: PMC2938740.
    85. Mehta SK, Tyring SK, Gilden DH, Cohrs RJ, Leal MJ, Castro VA, Feiveson AH, Ott CM, Pierson DL. Varicella-zoster virus in the saliva of patients with herpes zoster. J Infect Dis. 2008 Mar 01; 197(5):654-7. PMID: 18260763; PMCID: PMC2938732.
    86. Mueller NH, Graf LL, Shearer AJ, Owens GP, Gilden DH, Cohrs RJ. Construction of recombinant mouse IgG1 antibody directed against varicella zoster virus immediate early protein 63. Hybridoma (Larchmt). 2008 Feb; 27(1):1-10. PMID: 18294070; PMCID: PMC2938744.
    87. Quan D, Cohrs RJ, Mahalingam R, Gilden DH. Prevention of shingles: safety and efficacy of live zoster vaccine. Ther Clin Risk Manag. 2007 Aug; 3(4):633-9. PMID: 18472986; PMCID: PMC2374947.
    88. Nagel MA, Forghani B, Mahalingam R, Wellish MC, Cohrs RJ, Russman AN, Katzan I, Lin R, Gardner CJ, Gilden DH. The value of detecting anti-VZV IgG antibody in CSF to diagnose VZV vasculopathy. Neurology. 2007 Mar 27; 68(13):1069-73. PMID: 17287447.
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    89. Gilden DH, Mahalingam R, Cohrs RJ, Tyler KL. Herpesvirus infections of the nervous system. Nat Clin Pract Neurol. 2007 Feb; 3(2):82-94. PMID: 17279082.
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    90. Cohrs RJ, Gilden DH. Prevalence and abundance of latently transcribed varicella-zoster virus genes in human ganglia. J Virol. 2007 Mar; 81(6):2950-6. PMID: 17192313; PMCID: PMC1866015.
    91. Gary L, Gilden DH, Cohrs RJ. Epigenetic regulation of varicella-zoster virus open reading frames 62 and 63 in latently infected human trigeminal ganglia. J Virol. 2006 May; 80(10):4921-6. PMID: 16641283; PMCID: PMC1472082.
    92. Hoover SE, Cohrs RJ, Rangel ZG, Gilden DH, Munson P, Cohen JI. Downregulation of varicella-zoster virus (VZV) immediate-early ORF62 transcription by VZV ORF63 correlates with virus replication in vitro and with latency. J Virol. 2006 Apr; 80(7):3459-68. PMID: 16537613; PMCID: PMC1440367.
    93. Cohrs RJ, Gilden DH, Gomi Y, Yamanishi K, Cohen JI. Comparison of virus transcription during lytic infection of the Oka parental and vaccine strains of Varicella-Zoster virus. J Virol. 2006 Mar; 80(5):2076-82. PMID: 16474115; PMCID: PMC1395396.
    94. Cohrs RJ, Laguardia JJ, Gilden D. Distribution of latent herpes simplex virus type-1 and varicella zoster virus DNA in human trigeminal Ganglia. Virus Genes. 2005 Oct; 31(2):223-7. PMID: 16025248.
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    95. Deitch SB, Gilden DH, Wellish M, Smith J, Cohrs RJ, Mahalingam R. Array analysis of simian varicella virus gene transcription in productively infected cells in tissue culture. J Virol. 2005 May; 79(9):5315-25. PMID: 15827146; PMCID: PMC1082781.
    96. Gilden DH, Cohrs RJ, Mahalingam R. VZV vasculopathy and postherpetic neuralgia: progress and perspective on antiviral therapy. Neurology. 2005 Jan 11; 64(1):21-5. PMID: 15642898.
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    97. Cohrs RJ, Gilden DH, Mahalingam R. Varicella zoster virus latency, neurological disease and experimental models: an update. Front Biosci. 2004 Jan 01; 9:751-62. PMID: 14766405.
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    98. Mehta SK, Cohrs RJ, Forghani B, Zerbe G, Gilden DH, Pierson DL. Stress-induced subclinical reactivation of varicella zoster virus in astronauts. J Med Virol. 2004 Jan; 72(1):174-9. PMID: 14635028.
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    99. Cohrs RJ, Hurley MP, Gilden DH. Array analysis of viral gene transcription during lytic infection of cells in tissue culture with Varicella-Zoster virus. J Virol. 2003 Nov; 77(21):11718-32. PMID: 14557657; PMCID: PMC229365.
    100. Hevner R, Vilela M, Rostomily R, Cohrs R, Mahalingam R, Wellish M, Gilden DH. An unusual cause of trigeminal-distribution pain and tumour. Lancet Neurol. 2003 Sep; 2(9):567-71. PMID: 12941580.
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    101. Gilden DH, Cohrs RJ, Hayward AR, Wellish M, Mahalingam R. Chronic varicella-zoster virus ganglionitis--a possible cause of postherpetic neuralgia. J Neurovirol. 2003 Jun; 9(3):404-7. PMID: 12775423.
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    102. Cohrs RJ, Gilden DH, Kinchington PR, Grinfeld E, Kennedy PG. Varicella-zoster virus gene 66 transcription and translation in latently infected human Ganglia. J Virol. 2003 Jun; 77(12):6660-5. PMID: 12767985; PMCID: PMC156202.
    103. Cohrs RJ, Gilden DH. Varicella zoster virus transcription in latently-infected human ganglia. Anticancer Res. 2003 May-Jun; 23(3A):2063-9. PMID: 12894579.
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    104. Mitchell BM, Bloom DC, Cohrs RJ, Gilden DH, Kennedy PG. Herpes simplex virus-1 and varicella-zoster virus latency in ganglia. J Neurovirol. 2003 Apr; 9(2):194-204. PMID: 12707850.
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    105. Shenkar R, Elliott JP, Diener K, Gault J, Hu LJ, Cohrs RJ, Phang T, Hunter L, Breeze RE, Awad IA. Differential gene expression in human cerebrovascular malformations. Neurosurgery. 2003 Feb; 52(2):465-77; discussion 477-8. PMID: 12535382; PMCID: PMC2709524.
    106. Gilden DH, Cohrs RJ, Mahalingam R. Clinical and molecular pathogenesis of varicella virus infection. Viral Immunol. 2003; 16(3):243-58. PMID: 14583142.
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    107. Gilden DH, Mahalingam R, Cohrs RJ, Kleinschmidt-DeMasters BK, Forghani B. The protean manifestations of varicella-zoster virus vasculopathy. J Neurovirol. 2002 Dec; 8 Suppl 2:75-9. PMID: 12491155.
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    108. Cohrs RJ, Wischer J, Essman C, Gilden DH. Characterization of varicella-zoster virus gene 21 and 29 proteins in infected cells. J Virol. 2002 Jul; 76(14):7228-38. PMID: 12072522; PMCID: PMC136324.
    109. Cohrs RJ, Gilden DH. Human herpesvirus latency. Brain Pathol. 2001 Oct; 11(4):465-74. PMID: 11556692.
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    110. Gilden DH, Gesser R, Smith J, Wellish M, Laguardia JJ, Cohrs RJ, Mahalingam R. Presence of VZV and HSV-1 DNA in human nodose and celiac ganglia. Virus Genes. 2001; 23(2):145-7. PMID: 11724266.
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    111. Cohrs RJ, Randall J, Smith J, Gilden DH, Dabrowski C, van Der Keyl H, Tal-Singer R. Analysis of individual human trigeminal ganglia for latent herpes simplex virus type 1 and varicella-zoster virus nucleic acids using real-time PCR. J Virol. 2000 Dec; 74(24):11464-71. PMID: 11090142; PMCID: PMC112425.
    112. LaGuardia JJ, Cohrs RJ, Gilden DH. Numbers of neurons and non-neuronal cells in human trigeminal ganglia. Neurol Res. 2000 Sep; 22(6):565-6. PMID: 11045016.
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    113. Gilden DH, Kleinschmidt-DeMasters BK, LaGuardia JJ, Mahalingam R, Cohrs RJ. Neurologic complications of the reactivation of varicella-zoster virus. N Engl J Med. 2000 Mar 02; 342(9):635-45. PMID: 10699164.
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    114. LaGuardia JJ, Cohrs RJ, Gilden DH. Prevalence of varicella-zoster virus DNA in dissociated human trigeminal ganglion neurons and nonneuronal cells. J Virol. 1999 Oct; 73(10):8571-7. PMID: 10482610; PMCID: PMC112877.
    115. Mahalingam R, Lasher R, Wellish M, Cohrs RJ, Gilden DH. Localization of varicella-zoster virus gene 21 protein in virus-infected cells in culture. J Virol. 1998 Aug; 72(8):6832-7. PMID: 9658132; PMCID: PMC109892.
    116. Mahalingam R, Wellish M, White T, Soike K, Cohrs R, Kleinschmidt-DeMasters BK, Gilden DH. Infectious simian varicella virus expressing the green fluorescent protein. J Neurovirol. 1998 Aug; 4(4):438-44. PMID: 9718136.
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    117. Cohrs RJ, Barbour M, Gilden DH. Varicella-zoster virus gene 21: transcriptional start site and promoter region. J Virol. 1998 Jan; 72(1):42-7. PMID: 9420198; PMCID: PMC109347.
    118. Cohrs RJ, Barbour M, Gilden DH. Varicella-zoster virus (VZV) transcription during latency in human ganglia: detection of transcripts mapping to genes 21, 29, 62, and 63 in a cDNA library enriched for VZV RNA. J Virol. 1996 May; 70(5):2789-96. PMID: 8627753; PMCID: PMC190136.
    119. Mahalingam R, Wellish M, Cohrs R, Debrus S, Piette J, Rentier B, Gilden DH. Expression of protein encoded by varicella-zoster virus open reading frame 63 in latently infected human ganglionic neurons. Proc Natl Acad Sci U S A. 1996 Mar 05; 93(5):2122-4. PMID: 8700895; PMCID: PMC39920.
    120. Clarke P, Beer T, Cohrs R, Gilden DH. Configuration of latent varicella-zoster virus DNA. J Virol. 1995 Dec; 69(12):8151-4. PMID: 7494340; PMCID: PMC189772.
    121. Cohrs RJ, Barbour MB, Mahalingam R, Wellish M, Gilden DH. Varicella-zoster virus (VZV) transcription during latency in human ganglia: prevalence of VZV gene 21 transcripts in latently infected human ganglia. J Virol. 1995 Apr; 69(4):2674-8. PMID: 7884921; PMCID: PMC188953.
    122. Mahalingam R, Kido S, Wellish M, Cohrs R, Gilden DH. In situ polymerase chain reaction detection of varicella zoster virus in infected cells in culture. J Virol Methods. 1995 Mar; 52(1-2):21-33. PMID: 7769034.
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    123. Cohrs RJ, Srock K, Barbour MB, Owens G, Mahalingam R, Devlin ME, Wellish M, Gilden DH. Varicella-zoster virus (VZV) transcription during latency in human ganglia: construction of a cDNA library from latently infected human trigeminal ganglia and detection of a VZV transcript. J Virol. 1994 Dec; 68(12):7900-8. PMID: 7966580; PMCID: PMC237252.
    124. Mahalingam R, Wellish M, Lederer D, Forghani B, Cohrs R, Gilden D. Quantitation of latent varicella-zoster virus DNA in human trigeminal ganglia by polymerase chain reaction. J Virol. 1993 Apr; 67(4):2381-4. PMID: 8383249; PMCID: PMC240405.
    125. Clarke P, Rabkin SD, Inman MV, Mahalingam R, Cohrs R, Wellish M, Gilden DH. Molecular analysis of simian varicella virus DNA. Virology. 1992 Oct; 190(2):597-605. PMID: 1519354.
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    126. Cohrs R, Mahalingam R, Dueland AN, Wolf W, Wellish M, Gilden DH. Restricted transcription of varicella-zoster virus in latently infected human trigeminal and thoracic ganglia. J Infect Dis. 1992 Aug; 166 Suppl 1:S24-9. PMID: 1320647.
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    127. Gilden DH, Dueland AN, Devlin ME, Mahalingam R, Cohrs R. Varicella-zoster virus reactivation without rash. J Infect Dis. 1992 Aug; 166 Suppl 1:S30-4. PMID: 1320648.
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    128. Dueland AN, Martin JR, Devlin ME, Wellish M, Mahalingam R, Cohrs R, Soike KF, Gilden DH. Acute simian varicella infection. Clinical, laboratory, pathologic, and virologic features. Lab Invest. 1992 Jun; 66(6):762-73. PMID: 1602744.
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    129. Mahalingam R, Clarke P, Wellish M, Dueland AN, Soike KF, Gilden DH, Cohrs R. Prevalence and distribution of latent simian varicella virus DNA in monkey ganglia. Virology. 1992 May; 188(1):193-7. PMID: 1314451.
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    130. Devlin ME, Gilden DH, Mahalingam R, Dueland AN, Cohrs R. Peripheral blood mononuclear cells of the elderly contain varicella-zoster virus DNA. J Infect Dis. 1992 Apr; 165(4):619-22. PMID: 1313066.
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    131. Mahalingam R, Wellish MC, Dueland AN, Cohrs RJ, Gilden DH. Localization of herpes simplex virus and varicella zoster virus DNA in human ganglia. Ann Neurol. 1992 Apr; 31(4):444-8. PMID: 1316733.
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    132. Gilden DH, Mahalingam R, Dueland AN, Cohrs R. Herpes zoster: pathogenesis and latency. Prog Med Virol. 1992; 39:19-75. PMID: 1317598.
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    133. Gilden DH, Dueland AN, Cohrs R, Martin JR, Kleinschmidt-DeMasters BK, Mahalingam R. Preherpetic neuralgia. Neurology. 1991 Aug; 41(8):1215-8. PMID: 1866008.
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    134. Dueland AN, Devlin M, Martin JR, Mahalingam R, Cohrs R, Manz H, Trombley I, Gilden D. Fatal varicella-zoster virus meningoradiculitis without skin involvement. Ann Neurol. 1991 May; 29(5):569-72. PMID: 1650163.
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    135. Mahalingam R, Smith D, Wellish M, Wolf W, Dueland AN, Cohrs R, Soike K, Gilden D. Simian varicella virus DNA in dorsal root ganglia. Proc Natl Acad Sci U S A. 1991 Apr 01; 88(7):2750-2. PMID: 1849275; PMCID: PMC51316.
    136. Cohrs RJ, Torelli S, Prasad KN, Edwards-Prasad J, Sharma OK. Effect of vitamin E succinate and a cAMP-stimulating agent on the expression of c-myc and N-myc and H-ras in murine neuroblastoma cells. Int J Dev Neurosci. 1991; 9(2):187-94. PMID: 1647646.
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    137. Prasad KN, Cohrs RJ, Sharma OK. Decreased expressions of c-myc and H-ras oncogenes in vitamin E succinate induced morphologically differentiated murine B-16 melanoma cells in culture. Biochem Cell Biol. 1990 Nov; 68(11):1250-5. PMID: 2177340.
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    138. Mahalingam R, Wellish M, Wolf W, Dueland AN, Cohrs R, Vafai A, Gilden D. Latent varicella-zoster viral DNA in human trigeminal and thoracic ganglia. N Engl J Med. 1990 Sep 06; 323(10):627-31. PMID: 2166914.
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    139. Cohrs RJ, Condit RC, Pacha RF, Thompson CL, Sharma OK. Modulation of ppp(A2'p)nA-dependent RNase by a temperature-sensitive mutant of vaccinia virus. J Virol. 1989 Feb; 63(2):948-51. PMID: 2911126; PMCID: PMC247771.
    140. Cohrs RJ, Goswami BB, Sharma OK. Occurrence of 2-5A and RNA degradation in the chick oviduct during rapid estrogen withdrawal. Biochemistry. 1988 May 03; 27(9):3246-52. PMID: 2455540.
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    141. Cohrs RJ, Goswami BB, Sharma OK. Down regulation of c-myc, c-fos and erb-B during estrogen induced proliferation of the chick oviduct. Biochem Biophys Res Commun. 1988 Jan 15; 150(1):82-8. PMID: 3337730.
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    142. Cohrs R, Rouhandeh H. Analysis of Herpesvirus sylvilagus-induced proteins in infected rabbit kidney cells by two-dimensional gel electrophoresis. Intervirology. 1987; 28(4):206-20. PMID: 3449475.
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    143. Rouhandeh H, Cohrs R. Cloning and physical mapping of Herpesvirus sylvilagus DNA. Gene. 1987; 61(1):31-9. PMID: 2832255.
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    144. Cohrs R, Rouhandeh H. Characterization of the genome of Herpesvirus sylvilagus. Intervirology. 1987; 28(3):181-4. PMID: 3450678.
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    145. Sharma OK, Goswami BB, Cohrs RJ. Mechanism of growth inhibition of DNA containing viruses by interferon: role of 2-5A. Prog Clin Biol Res. 1985; 202:317-24. PMID: 2421310.
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    146. Rouhandeh H, Cohrs R. Modification of viral structural proteins of herpesvirus sylvilagus by glycosylation and phosphorylation. J Virol. 1984 Dec; 52(3):1005-8. PMID: 6492259; PMCID: PMC254630.
    147. Cohrs R, Rouhandeh H. Herpesvirus sylvilagus I. Polypeptides of virions and nucleocapsids. J Virol. 1982 Mar; 41(3):1063-72. PMID: 7097852; PMCID: PMC256844.
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