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James E Orfila

TitleInstructor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-AN General Operations

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Dietz RM, Cruz-Torres I, Orfila JE, Patsos OP, Shimizu K, Chalmers N, Deng G, Tiemeier E, Quillinan N, Herson PS. Reversal of Global Ischemia-Induced Cognitive Dysfunction by Delayed Inhibition of TRPM2 Ion Channels. Transl Stroke Res. 2019 Jun 28. PMID: 31250378.
      View in: PubMed
    2. Hippensteel JA, Anderson BJ, Orfila JE, McMurtry SA, Dietz RM, Su G, Ford JA, Oshima K, Yang Y, Zhang F, Han X, Yu Y, Liu J, Linhardt RJ, Meyer NJ, Herson PS, Schmidt EP. Circulating heparan sulfate fragments mediate septic cognitive dysfunction. J Clin Invest. 2019 Apr 01; 129(4):1779-1784. PMID: 30720464.
      View in: PubMed
    3. Orfila JE, Dietz RM, Rodgers KM, Dingman A, Patsos OP, Cruz-Torres I, Grewal H, Strnad F, Schroeder C, Herson PS. Experimental pediatric stroke shows age-specific recovery of cognition and role of hippocampal Nogo-A receptor signaling. J Cereb Blood Flow Metab. 2019 Feb 14; 271678X19828581. PMID: 30762478.
      View in: PubMed
    4. Quillinan N, Dingman AL, Deng G, Tatum S, Orfila JE, Clevenger AC, Klawitter J, Traystman RJ, Herson PS. Single dose of 17ß-estradiol provides transient neuroprotection in female juvenile mice after cardiac-arrest and cardiopulmonary resuscitation. Neurochem Int. 2019 07; 127:80-86. PMID: 30471325.
      View in: PubMed
    5. Orfila JE, McKinnon N, Moreno M, Deng G, Chalmers N, Dietz RM, Herson PS, Quillinan N. Cardiac Arrest Induces Ischemic Long-Term Potentiation of Hippocampal CA1 Neurons That Occludes Physiological Long-Term Potentiation. Neural Plast. 2018; 2018:9275239. PMID: 29853851.
      View in: PubMed
    6. Dietz RM, Orfila JE, Rodgers KM, Patsos OP, Deng G, Chalmers N, Quillinan N, Traystman RJ, Herson PS. Juvenile cerebral ischemia reveals age-dependent BDNF-TrkB signaling changes: Novel mechanism of recovery and therapeutic intervention. J Cereb Blood Flow Metab. 2018 Dec; 38(12):2223-2235. PMID: 29611441.
      View in: PubMed
    7. Clevenger AC, Kim H, Salcedo E, Yonchek JC, Rodgers KM, Orfila JE, Dietz RM, Quillinan N, Traystman RJ, Herson PS. Endogenous Sex Steroids Dampen Neuroinflammation and Improve Outcome of Traumatic Brain Injury in Mice. J Mol Neurosci. 2018 Mar; 64(3):410-420. PMID: 29450697.
      View in: PubMed
    8. Orfila JE, Grewal H, Dietz RM, Strnad F, Shimizu T, Moreno M, Schroeder C, Yonchek J, Rodgers KM, Dingman A, Bernard TJ, Quillinan N, Macklin WB, Traystman RJ, Herson PS. Delayed inhibition of tonic inhibition enhances functional recovery following experimental ischemic stroke. J Cereb Blood Flow Metab. 2019 Jun; 39(6):1005-1014. PMID: 29283314.
      View in: PubMed
    9. Joksimovic SM, Eggan P, Izumi Y, Joksimovic SL, Tesic V, Dietz RM, Orfila JE, DiGruccio MR, Herson PS, Jevtovic-Todorovic V, Zorumski CF, Todorovic SM. The role of T-type calcium channels in the subiculum: to burst or not to burst? J Physiol. 2017 10 01; 595(19):6327-6348. PMID: 28744923.
      View in: PubMed
    10. Deng G, Orfila JE, Dietz RM, Moreno-Garcia M, Rodgers KM, Coultrap SJ, Quillinan N, Traystman RJ, Bayer KU, Herson PS. Autonomous CaMKII Activity as a Drug Target for Histological and Functional Neuroprotection after Resuscitation from Cardiac Arrest. Cell Rep. 2017 01 31; 18(5):1109-1117. PMID: 28147268.
      View in: PubMed
    11. Dietz RM, Deng G, Orfila JE, Hui X, Traystman RJ, Herson PS. Therapeutic hypothermia protects against ischemia-induced impairment of synaptic plasticity following juvenile cardiac arrest in sex-dependent manner. Neuroscience. 2016 06 14; 325:132-41. PMID: 27033251.
      View in: PubMed
    12. Shimizu K, Quillinan N, Orfila JE, Herson PS. Sirtuin-2 mediates male specific neuronal injury following experimental cardiac arrest through activation of TRPM2 ion channels. Exp Neurol. 2016 Jan; 275 Pt 1:78-83. PMID: 26522013.
      View in: PubMed
    13. Orfila JE, Shimizu K, Garske AK, Deng G, Maylie J, Traystman RJ, Quillinan N, Adelman JP, Herson PS. Increasing small conductance Ca2+-activated potassium channel activity reverses ischemia-induced impairment of long-term potentiation. Eur J Neurosci. 2014 Oct; 40(8):3179-88. PMID: 25080203.
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    14. Carcoba LM, Orfila JE, Natividad LA, Torres OV, Pipkin JA, Ferree PL, Castañeda E, Moss DE, O'Dell LE. Cholinergic transmission during nicotine withdrawal is influenced by age and pre-exposure to nicotine: implications for teenage smoking. Dev Neurosci. 2014; 36(3-4):347-55. PMID: 24854235.
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    15. Ballesteros KA, Sikorski A, Orfila JE, Martinez JL. Effects of inhaled anesthetic isoflurane on long-term potentiation of CA3 pyramidal cell afferents in vivo. Int J Gen Med. 2012; 5:935-42. PMID: 23204857.
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    16. Tejeda HA, Natividad LA, Orfila JE, Torres OV, O'Dell LE. Dysregulation of kappa-opioid receptor systems by chronic nicotine modulate the nicotine withdrawal syndrome in an age-dependent manner. Psychopharmacology (Berl). 2012 Nov; 224(2):289-301. PMID: 22659976.
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    17. Thompson KJ, Mata ML, Orfila JE, Barea-Rodriguez EJ, Martinez JL. Metabotropic glutamate receptor antagonist AIDA blocks induction of mossy fiber-CA3 LTP in vivo. J Neurophysiol. 2005 May; 93(5):2668-73. PMID: 15548625.
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    18. Lebaron RG, Hernandez RV, Navarro MM, Curry LR, Orfila JE, Martinez JL. A focal adhesion-like process underlies induction of long-term potentiation in the Schaffer collateral-CA1 region of the hippocampus. Neuron Glia Biol. 2004 Nov; 1(4):385-93. PMID: 18634595.
      View in: PubMed
    19. Thompson KJ, Orfila JE, Achanta P, Martinez JL. Gene expression associated with in vivo induction of early phase-long-term potentiation (LTP) in the hippocampal mossy fiber-Cornus Ammonis (CA)3 pathway. Cell Mol Biol (Noisy-le-grand). 2003 Dec; 49(8):1281-7. PMID: 14983999.
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    20. LeBaron RG, Hernandez RV, Orfila JE, Martinez JL. An integrin binding peptide reduces rat CA1 hippocampal long-term potentiation during the first few minutes following theta burst stimulation. Neurosci Lett. 2003 Mar 27; 339(3):199-202. PMID: 12633887.
      View in: PubMed
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