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Diana I Jalal

TitleAssociate Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus

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    K23DK088833     (JALAL, DIANA I)Sep 15, 2010 - Aug 31, 2015
    Uric Acid as a Mediator of Endothelial Dysfunction in Patients with CKD
    Role: Principal Investigator

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Mehta T, Buzkova P, Kizer JR, Djousse L, Chonchol M, Mukamal KJ, Shlipak M, Ix JH, Jalal D. Higher plasma transforming growth factor (TGF)-ß is associated with kidney disease in older community dwelling adults. BMC Nephrol. 2017 Mar 21; 18(1):98. PMID: 28327102.
      View in: PubMed
    2. Umanath K, Greco B, Jalal DI, McFadden M, Sika M, Koury MJ, Niecestro R, Hunsicker LG, Greene T, Lewis JB, Dwyer JP. The safety of achieved iron stores and their effect on IV iron and ESA use: post-hoc results from a randomized trial of ferric citrate as a phosphate binder in dialysis?. Clin Nephrol. 2017 Mar; 87 (2017)(3):124-133. PMID: 28128726.
      View in: PubMed
    3. Jalal DI, Decker E, Perrenoud L, Nowak KL, Bispham N, Mehta T, Smits G, You Z, Seals D, Chonchol M, Johnson RJ. Vascular Function and Uric Acid-Lowering in Stage 3 CKD. J Am Soc Nephrol. 2017 Mar; 28(3):943-952. PMID: 27620990.
      View in: PubMed
    4. Jalal D, McFadden M, Dwyer JP, Umanath K, Aguilar E, Yagil Y, Greco B, Sika M, Lewis JB, Greene T, Goral S. Adherence rates to ferric citrate as compared to active control in patients with end stage kidney disease on dialysis. Hemodial Int. 2017 Apr; 21(2):243-249. PMID: 27615161.
      View in: PubMed
    5. Jalal DI. Hyperuricemia, the kidneys, and the spectrum of associated diseases: a narrative review. Curr Med Res Opin. 2016 Nov; 32(11):1863-1869. PMID: 27470664.
      View in: PubMed
    6. Barzilay JI, Bužková P, Fink HA, Cauley JA, Robbins JA, Garimella PS, Jalal DI, Mukamal KJ. Systemic markers of microvascular disease and bone mineral density in older adults : The cardiovascular health study. Osteoporos Int. 2016 Nov; 27(11):3217-3225. PMID: 27250972.
      View in: PubMed
    7. Gist KM, Kaufman J, da Cruz EM, Friesen RH, Crumback SL, Linders M, Edelstein C, Altmann C, Palmer C, Jalal D, Faubel S. A Decline in Intraoperative Renal Near-Infrared Spectroscopy Is Associated With Adverse Outcomes in Children Following Cardiac Surgery. Pediatr Crit Care Med. 2016 Apr; 17(4):342-9. PMID: 26914625.
      View in: PubMed
    8. Bethel M, Bužková P, Fink HA, Robbins JA, Cauley JA, Lee J, Barzilay JI, Jalal DI, Carbone LD. Soluble CD14 and fracture risk. Osteoporos Int. 2016 May; 27(5):1755-63. PMID: 26659065.
      View in: PubMed
    9. Thurman JM, Wong M, Renner B, Frazer-Abel A, Giclas PC, Joy MS, Jalal D, Radeva MK, Gassman J, Gipson DS, Kaskel F, Friedman A, Trachtman H. Complement Activation in Patients with Focal Segmental Glomerulosclerosis. PLoS One. 2015; 10(9):e0136558. PMID: 26335102; PMCID: PMC4559462.
    10. Madero M, Rodríguez Castellanos FE, Jalal D, Villalobos-Martín M, Salazar J, Vazquez-Rangel A, Johnson RJ, Sanchez-Lozada LG. A pilot study on the impact of a low fructose diet and allopurinol on clinic blood pressure among overweight and prehypertensive subjects: a randomized placebo controlled trial. J Am Soc Hypertens. 2015 Nov; 9(11):837-44. PMID: 26329473.
      View in: PubMed
    11. Bjornstad P, Lanaspa MA, Ishimoto T, Kosugi T, Kume S, Jalal D, Maahs DM, Snell-Bergeon JK, Johnson RJ, Nakagawa T. Fructose and uric acid in diabetic nephropathy. Diabetologia. 2015 Sep; 58(9):1993-2002. PMID: 26049401; PMCID: PMC4826347.
    12. Fink HA, Bužková P, Garimella PS, Mukamal KJ, Cauley JA, Kizer JR, Barzilay JI, Jalal DI, Ix JH. Association of Fetuin-A With Incident Fractures in Community-Dwelling Older Adults: The Cardiovascular Health Study. J Bone Miner Res. 2015 Aug; 30(8):1394-402. PMID: 25656814.
      View in: PubMed
    13. Umanath K, Jalal DI, Greco BA, Umeukeje EM, Reisin E, Manley J, Zeig S, Negoi DG, Hiremath AN, Blumenthal SS, Sika M, Niecestro R, Koury MJ, Ma KN, Greene T, Lewis JB, Dwyer JP. Ferric Citrate Reduces Intravenous Iron and Erythropoiesis-Stimulating Agent Use in ESRD. J Am Soc Nephrol. 2015 Oct; 26(10):2578-87. PMID: 25736045; PMCID: PMC4587699 [Available on 10/01/16].
    14. Mehta T, Nuccio E, McFann K, Madero M, Sarnak MJ, Jalal D. Association of Uric Acid With Vascular Stiffness in the Framingham Heart Study. Am J Hypertens. 2015 Jul; 28(7):877-83. PMID: 25552515; PMCID: PMC4542908.
    15. Mehta T, Bužková P, Sarnak MJ, Chonchol M, Cauley JA, Wallace E, Fink HA, Robbins J, Jalal D. Serum urate levels and the risk of hip fractures: data from the Cardiovascular Health Study. Metabolism. 2015 Mar; 64(3):438-46. PMID: 25491429; PMCID: PMC4312534.
    16. Jalal D, Weis B, Zuber K, Davis J. CKD and the interdisciplinary team: the logic behind the trend. Adv Chronic Kidney Dis. 2014 Jul; 21(4):331-2. PMID: 24969382.
      View in: PubMed
    17. Jablonski KL, Decker E, Perrenoud L, Kendrick J, Chonchol M, Seals DR, Jalal D. Assessment of vascular function in patients with chronic kidney disease. J Vis Exp. 2014 Jun 16; (88). PMID: 24962357; PMCID: PMC4193838.
    18. Bjornstad P, Paul Wadwa R, Sirota JC, Snell-Bergeon JK, McFann K, Rewers M, Rivard CJ, Jalal D, Chonchol MB, Johnson RJ, Maahs DM. Serum uric acid and hypertension in adults: a paradoxical relationship in type 1 diabetes. J Clin Hypertens (Greenwich). 2014 Apr; 16(4):283-8. PMID: 24667019; PMCID: PMC3989383.
    19. Bjornstad P, Snell-Bergeon JK, McFann K, Wadwa RP, Rewers M, Rivard CJ, Jalal D, Chonchol MB, Johnson RJ, Maahs DM. Serum uric acid and insulin sensitivity in adolescents and adults with and without type 1 diabetes. J Diabetes Complications. 2014 May-Jun; 28(3):298-304. PMID: 24461546; PMCID: PMC4004676.
    20. Chen W, Roncal-Jimenez C, Lanaspa M, Gerard S, Chonchol M, Johnson RJ, Jalal D. Uric acid suppresses 1 alpha hydroxylase in vitro and in vivo. Metabolism. 2014 Jan; 63(1):150-60. PMID: 24269076; PMCID: PMC3859721.
    21. Bjornstad P, Snell-Bergeon JK, Rewers M, Jalal D, Chonchol MB, Johnson RJ, Maahs DM. Early diabetic nephropathy: a complication of reduced insulin sensitivity in type 1 diabetes. Diabetes Care. 2013 Nov; 36(11):3678-83. PMID: 24026551; PMCID: PMC3816872.
    22. Maahs DM, Caramori L, Cherney DZ, Galecki AT, Gao C, Jalal D, Perkins BA, Pop-Busui R, Rossing P, Mauer M, Doria A. Uric acid lowering to prevent kidney function loss in diabetes: the preventing early renal function loss (PERL) allopurinol study. Curr Diab Rep. 2013 Aug; 13(4):550-9. PMID: 23649945; PMCID: PMC3703487.
    23. Maahs DM, Jalal D, Chonchol M, Johnson RJ, Rewers M, Snell-Bergeon JK. Impaired renal function further increases odds of 6-year coronary artery calcification progression in adults with type 1 diabetes: the CACTI study. Diabetes Care. 2013 Sep; 36(9):2607-14. PMID: 23835686; PMCID: PMC3747879.
    24. Johnson RJ, Nakagawa T, Jalal D, Sánchez-Lozada LG, Kang DH, Ritz E. Uric acid and chronic kidney disease: which is chasing which? Nephrol Dial Transplant. 2013 Sep; 28(9):2221-8. PMID: 23543594; PMCID: PMC4318947.
    25. Feig DI, Madero M, Jalal DI, Sanchez-Lozada LG, Johnson RJ. Uric acid and the origins of hypertension. J Pediatr. 2013 May; 162(5):896-902. PMID: 23403249.
      View in: PubMed
    26. Sirota JC, McFann K, Targher G, Chonchol M, Jalal DI. Association between nonalcoholic liver disease and chronic kidney disease: an ultrasound analysis from NHANES 1988-1994. Am J Nephrol. 2012; 36(5):466-71. PMID: 23128368; PMCID: PMC3563287.
    27. Jalal DI, Chonchol M, Chen W, Targher G. Uric acid as a target of therapy in CKD. Am J Kidney Dis. 2013 Jan; 61(1):134-46. PMID: 23058478; PMCID: PMC3525781.
    28. Sirota JC, McFann K, Targher G, Johnson RJ, Chonchol M, Jalal DI. Elevated serum uric acid levels are associated with non-alcoholic fatty liver disease independently of metabolic syndrome features in the United States: Liver ultrasound data from the National Health and Nutrition Examination Survey. Metabolism. 2013 Mar; 62(3):392-9. PMID: 23036645; PMCID: PMC3565047.
    29. Jalal D, Chonchol M, Etgen T, Sander D. C-reactive protein as a predictor of cardiovascular events in elderly patients with chronic kidney disease. J Nephrol. 2012 Sep-Oct; 25(5):719-25. PMID: 22038335; PMCID: PMC3704176.
    30. Jalal DI, Jablonski KL, McFann K, Chonchol MB, Seals DR. Vascular endothelial function is not related to serum uric acid in healthy adults. Am J Hypertens. 2012 Apr; 25(4):407-13. PMID: 22237152; PMCID: PMC3309158.
    31. Shi Y, Chen W, Jalal D, Li Z, Chen W, Mao H, Yang Q, Johnson RJ, Yu X. Clinical outcome of hyperuricemia in IgA nephropathy: a retrospective cohort study and randomized controlled trial. Kidney Blood Press Res. 2012; 35(3):153-60. PMID: 22116196; PMCID: PMC3242707.
    32. Maahs DM, Prentice N, McFann K, Snell-Bergeon JK, Jalal D, Bishop FK, Aragon B, Wadwa RP. Age and sex influence cystatin C in adolescents with and without type 1 diabetes. Diabetes Care. 2011 Nov; 34(11):2360-2. PMID: 21926294; PMCID: PMC3198267.
    33. Jalal DI, Maahs DM, Hovind P, Nakagawa T. Uric acid as a mediator of diabetic nephropathy. Semin Nephrol. 2011 Sep; 31(5):459-65. PMID: 22000654; PMCID: PMC3197214.
    34. Maahs DM, Jalal D, McFann K, Rewers M, Snell-Bergeon JK. Systematic shifts in cystatin C between 2006 and 2010. Clin J Am Soc Nephrol. 2011 Aug; 6(8):1952-5. PMID: 21784814; PMCID: PMC3156426.
    35. Madero M, Arriaga JC, Jalal D, Rivard C, McFann K, Pérez-Méndez O, Vázquez A, Ruiz A, Lanaspa MA, Jimenez CR, Johnson RJ, Lozada LG. The effect of two energy-restricted diets, a low-fructose diet versus a moderate natural fructose diet, on weight loss and metabolic syndrome parameters: a randomized controlled trial. Metabolism. 2011 Nov; 60(11):1551-9. PMID: 21621801.
      View in: PubMed
    36. Roncal-Jimenez CA, Lanaspa MA, Rivard CJ, Nakagawa T, Sanchez-Lozada LG, Jalal D, Andres-Hernando A, Tanabe K, Madero M, Li N, Cicerchi C, Mc Fann K, Sautin YY, Johnson RJ. Sucrose induces fatty liver and pancreatic inflammation in male breeder rats independent of excess energy intake. Metabolism. 2011 Sep; 60(9):1259-70. PMID: 21489572; PMCID: PMC3137694.
    37. Kanbay M, Yilmaz MI, Sonmez A, Turgut F, Saglam M, Cakir E, Yenicesu M, Covic A, Jalal D, Johnson RJ. Serum uric acid level and endothelial dysfunction in patients with nondiabetic chronic kidney disease. Am J Nephrol. 2011; 33(4):298-304. PMID: 21389694; PMCID: PMC3064939.
    38. Madero M, Perez-Pozo SE, Jalal D, Johnson RJ, Sánchez-Lozada LG. Dietary fructose and hypertension. Curr Hypertens Rep. 2011 Feb; 13(1):29-35. PMID: 20957458.
      View in: PubMed
    39. Rodrigues TC, Maahs DM, Johnson RJ, Jalal DI, Kinney GL, Rivard C, Rewers M, Snell-Bergeon JK. Serum uric acid predicts progression of subclinical coronary atherosclerosis in individuals without renal disease. Diabetes Care. 2010 Nov; 33(11):2471-3. PMID: 20798338; PMCID: PMC2963516.
    40. Jalal DI, Smits G, Johnson RJ, Chonchol M. Increased fructose associates with elevated blood pressure. J Am Soc Nephrol. 2010 Sep; 21(9):1543-9. PMID: 20595676; PMCID: PMC3013529.
    41. Jalal DI, Chonchol M, Targher G. Disorders of hemostasis associated with chronic kidney disease. Semin Thromb Hemost. 2010 Feb; 36(1):34-40. PMID: 20391294.
      View in: PubMed
    42. Mazzali M, Kanbay M, Segal MS, Shafiu M, Jalal D, Feig DI, Johnson RJ. Uric acid and hypertension: cause or effect? Curr Rheumatol Rep. 2010 Apr; 12(2):108-17. PMID: 20425019.
      View in: PubMed
    43. Jalal DI, Rivard CJ, Johnson RJ, Maahs DM, McFann K, Rewers M, Snell-Bergeon JK. Serum uric acid levels predict the development of albuminuria over 6 years in patients with type 1 diabetes: findings from the Coronary Artery Calcification in Type 1 Diabetes study. Nephrol Dial Transplant. 2010 Jun; 25(6):1865-9. PMID: 20064950; PMCID: PMC2902891.
    44. Zhang W, Xia X, Jalal DI, Kuncewicz T, Xu W, Lesage GD, Kone BC. Aldosterone-sensitive repression of ENaCalpha transcription by a histone H3 lysine-79 methyltransferase. Am J Physiol Cell Physiol. 2006 Mar; 290(3):C936-46. PMID: 16236820; PMCID: PMC3009459.
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