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Joan E Hooper

TitleAssociate Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-Cell and Devopmental Bio
Phone303/724-3417

    Collapse Research 
    Collapse research activities and funding
    R21DE028613     (HOOPER, JOAN E)Apr 1, 2019 - Mar 31, 2021
    NIH
    Signaling interactions underlying Fusion at the Primary palate
    Role: Principal Investigator
    R03DE024598     (HOOPER, JOAN E)Sep 1, 2014 - Aug 31, 2017
    NIH
    Functional genomics to identify miRNA targets in the developing face
    Role: Principal Investigator
    U01DE024429     (WILLIAMS, TREVOR J)Jul 3, 2014 - Apr 30, 2019
    NIH
    RNA dynamics in the developing mouse face
    Role: Co-Principal Investigator
    R01GM069881     (HOOPER, JOAN E)Aug 1, 2004 - Jul 31, 2010
    NIH
    Mechanism of Hedgehog signal transduction
    Role: Principal Investigator
    R01GM045396     (HOOPER, JOAN E)Jan 1, 1991 - Jan 31, 2002
    NIH
    CELL INTERACTIONS ORGANIZING THE INSECT SEGMENT
    Role: Principal Investigator
    R29GM045396     (HOOPER, JOAN E)Jan 1, 1991 - Dec 31, 1995
    NIH
    CELL INTERACTIONS ORGANIZING THE INSECT SEGMENT
    Role: Principal Investigator
    F32HD006784     (HOOPER, JOAN E)Mar 4, 1986
    NIH
    MOLECULAR GENETICS OF PATCHED A SEGMENTATION GENE
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Samuels BD, Aho R, Brinkley JF, Bugacov A, Feingold E, Fisher S, Gonzalez-Reiche AS, Hacia JG, Hallgrimsson B, Hansen K, Harris MP, Ho TV, Holmes G, Hooper JE, Jabs EW, Jones KL, Kesselman C, Klein OD, Leslie EJ, Li H, Liao EC, Long H, Lu N, Maas RL, Marazita ML, Mohammed J, Prescott S, Schuler R, Selleri L, Spritz RA, Swigut T, van Bakel H, Visel A, Welsh I, Williams C, Williams TJ, Wysocka J, Yuan Y, Chai Y. FaceBase 3: analytical tools and FAIR resources for craniofacial and dental research. Development. 2020 09 21; 147(18). PMID: 32958507.
      View in: PubMed
    2. Hooper JE, Jones KL, Smith FJ, Williams T, Li H. An Alternative Splicing Program for Mouse Craniofacial Development. Front Physiol. 2020; 11:1099. PMID: 33013468.
      View in: PubMed
    3. Li H, Jones KL, Hooper JE, Williams T. The molecular anatomy of mammalian upper lip and primary palate fusion at single cell resolution. Development. 2019 06 17; 146(12). PMID: 31118233.
      View in: PubMed
    4. Hooper JE, Feng W, Li H, Leach SM, Phang T, Siska C, Jones KL, Spritz RA, Hunter LE, Williams T. Systems biology of facial development: contributions of ectoderm and mesenchyme. Dev Biol. 2017 06 01; 426(1):97-114. PMID: 28363736.
      View in: PubMed
    5. Ding HL, Hooper JE, Batzel P, Eames BF, Postlethwait JH, Artinger KB, Clouthier DE. MicroRNA Profiling during Craniofacial Development: Potential Roles for Mir23b and Mir133b. Front Physiol. 2016; 7:281. PMID: 27471470.
      View in: PubMed
    6. Brinkley JF, Fisher S, Harris MP, Holmes G, Hooper JE, Jabs EW, Jones KL, Kesselman C, Klein OD, Maas RL, Marazita ML, Selleri L, Spritz RA, van Bakel H, Visel A, Williams TJ, Wysocka J, Chai Y. The FaceBase Consortium: a comprehensive resource for craniofacial researchers. Development. 2016 07 15; 143(14):2677-88. PMID: 27287806.
      View in: PubMed
    7. Hooper JE. A survey of software for genome-wide discovery of differential splicing in RNA-Seq data. Hum Genomics. 2014 Jan 21; 8:3. PMID: 24447644.
      View in: PubMed
    8. Lee JP, Brauweiler A, Rudolph M, Hooper JE, Drabkin HA, Gemmill RM. The TRC8 ubiquitin ligase is sterol regulated and interacts with lipid and protein biosynthetic pathways. Mol Cancer Res. 2010 Jan; 8(1):93-106. PMID: 20068067.
      View in: PubMed
    9. Bankers CM, Hooper JE. Clonal analysis of Hedgehog signaling in Drosophila somatic tissues. Methods Mol Biol. 2007; 397:145-60. PMID: 18025720.
      View in: PubMed
    10. Kent D, Bush EW, Hooper JE. Roadkill attenuates Hedgehog responses through degradation of Cubitus interruptus. Development. 2006 May; 133(10):2001-10. PMID: 16651542.
      View in: PubMed
    11. Gemmill RM, Lee JP, Chamovitz DA, Segal D, Hooper JE, Drabkin HA. Growth suppression induced by the TRC8 hereditary kidney cancer gene is dependent upon JAB1/CSN5. Oncogene. 2005 May 12; 24(21):3503-11. PMID: 15735686.
      View in: PubMed
    12. Hooper JE, Scott MP. Communicating with Hedgehogs. Nat Rev Mol Cell Biol. 2005 Apr; 6(4):306-17. PMID: 15803137.
      View in: PubMed
    13. Ogden SK, Ascano M, Stegman MA, Suber LM, Hooper JE, Robbins DJ. Identification of a functional interaction between the transmembrane protein Smoothened and the kinesin-related protein Costal2. Curr Biol. 2003 Nov 11; 13(22):1998-2003. PMID: 14614827.
      View in: PubMed
    14. Hooper JE. Smoothened translates Hedgehog levels into distinct responses. Development. 2003 Sep; 130(17):3951-63. PMID: 12874118.
      View in: PubMed
    15. Gemmill RM, Bemis LT, Lee JP, Sozen MA, Baron A, Zeng C, Erickson PF, Hooper JE, Drabkin HA. The TRC8 hereditary kidney cancer gene suppresses growth and functions with VHL in a common pathway. Oncogene. 2002 May 16; 21(22):3507-16. PMID: 12032852.
      View in: PubMed
    16. Thackray VG, Young RH, Hooper JE, Nordeen SK. Estrogen agonist and antagonist action on the human estrogen receptor in Drosophila. Endocrinology. 2000 Oct; 141(10):3912-5. PMID: 11014249.
      View in: PubMed
    17. Hall JM, Hooper JE, Finger TE. Expression of sonic hedgehog, patched, and Gli1 in developing taste papillae of the mouse. J Comp Neurol. 1999 Apr 05; 406(2):143-55. PMID: 10096602.
      View in: PubMed
    18. Von Ohlen T, Hooper JE. The ciD mutation encodes a chimeric protein whose activity is regulated by Wingless signaling. Dev Biol. 1999 Apr 01; 208(1):147-56. PMID: 10075848.
      View in: PubMed
    19. Von Ohlen T, Hooper JE. Hedgehog signaling regulates transcription through Gli/Ci binding sites in the wingless enhancer. Mech Dev. 1997 Nov; 68(1-2):149-56. PMID: 9431812.
      View in: PubMed
    20. Von Ohlen T, Lessing D, Nusse R, Hooper JE. Hedgehog signaling regulates transcription through cubitus interruptus, a sequence-specific DNA binding protein. Proc Natl Acad Sci U S A. 1997 Mar 18; 94(6):2404-9. PMID: 9122207.
      View in: PubMed
    21. Hooper JE. Distinct pathways for autocrine and paracrine Wingless signalling in Drosophila embryos. Nature. 1994 Dec 01; 372(6505):461-4. PMID: 7984239.
      View in: PubMed
    22. Hooper JE, P?rez-Alonso M, Bermingham JR, Prout M, Rocklein BA, Wagenbach M, Edstrom JE, de Frutos R, Scott MP. Comparative studies of Drosophila Antennapedia genes. Genetics. 1992 Oct; 132(2):453-69. PMID: 1358753.
      View in: PubMed
    23. Hooper JE, Scott MP. The molecular genetic basis of positional information in insect segments. Results Probl Cell Differ. 1992; 18:1-48. PMID: 1475532.
      View in: PubMed
    24. Hooper JE, Scott MP. The Drosophila patched gene encodes a putative membrane protein required for segmental patterning. Cell. 1989 Nov 17; 59(4):751-65. PMID: 2582494.
      View in: PubMed
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