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Hugo R Rosen

TitleProfessor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-MED

    Collapse Research 
    Collapse research activities and funding
    T32DK007038     (ROSEN, HUGO RAMON)Jul 1, 1975 - Jun 30, 2021
    NIH/NIDDK
    Gastrointestinal Diseases Training Grant
    Role: Principal Investigator

    U01DK060342     (ROSEN, HUGO RAMON)Sep 30, 2001 - Apr 30, 2007
    NIH/NIDDK
    Cellular Immune Mechanisms of Resistance to HCV Therapy
    Role: Principal Investigator

    R01DK060590     (ROSEN, HUGO RAMON)Sep 15, 2002 - Aug 31, 2011
    NIH/NIDDK
    Immune Responses in Acute Hepatitis C Infection
    Role: Principal Investigator

    U19AI066328     (ROSEN, HUGO RAMON)Jul 1, 2005 - Aug 31, 2015
    NIH/NIAID
    Colorado Hepatitis C Cooperative Research Center
    Role: Principal Investigator

    R01DK071560     (ROSEN, HUGO RAMON)Sep 30, 2005 - Jul 31, 2010
    NIH/NIDDK
    Innate Immune Responses During Therapy for Chronic HCV
    Role: Principal Investigator

    K24AI083742     (ROSEN, HUGO RAMON)Sep 18, 2009 - Jul 31, 2014
    NIH/NIAID
    Midcareer Investigator Award in Patient-Oriented Research (K24)
    Role: Principal Investigator

    I01CX000111     (ROSEN, HUGO RAMON)Oct 1, 2009 - Sep 30, 2013
    VA
    Functional attributes of CD8+ T cells in recovery of hepatitis C virus infection
    Role: Principal Investigator

    R56AI100991     (ROSEN, HUGO RAMON)Sep 20, 2012 - Feb 28, 2014
    NIH/NIAID
    HEPATITIS C VIRAL INFECTION IN HUMAN PREGNANCY
    Role: Principal Investigator

    R21AI103361     (ROSEN, HUGO RAMON)May 15, 2013 - Apr 30, 2015
    NIH/NIAID
    Hepatitis C viral sensing by non-parenchymal liver cells (NPC)
    Role: Principal Investigator

    I01BX002201     (ROSEN, HUGO RAMON)Jan 1, 2014 - Dec 31, 2017
    VA
    Novel Aspects of Hepatic Innate and Adaptive Immunity to HCV Infection
    Role: Principal Investigator

    R01HD075549     (ROSEN, HUGO RAMON)Feb 7, 2014 - Jan 31, 2019
    NIH/NICHD
    INNATE AND ADAPTIVE IMMUNITY TO HCV IN HUMAN PREGNANCY
    Role: Co-Principal Investigator

    R01AI127463     (GALE, MICHAEL J)Dec 15, 2016 - Nov 30, 2021
    NIH/NIAID
    Mechanisms of hepatic innate immune activation by HCV
    Role: Co-Principal Investigator

    R01AI120622     (ROSEN, HUGO RAMON)Feb 14, 2017 - Jan 31, 2021
    NIH/NIAID
    RESUBMISSION -R01 AI120622 ?Restoration of Immunity and Function with DAA Treatment in HCV infection
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Rosen E, Bakshi N, Watters A, Rosen HR, Mehler PS. Hepatic Complications of Anorexia Nervosa. Dig Dis Sci. 2017 Sep 20. PMID: 28932925.
      View in: PubMed
    2. Rosen HR, Ghany MG, Chung RT, Lok ASF. NAM 2017 report: A national plan to eliminate hepatitis B and C in the United States by 2030 and the AASLD's response. Hepatology. 2017 Oct; 66(4):1020-1022. PMID: 28714210.
      View in: PubMed
    3. Cobb DA, Golden-Mason L, Rosen HR, Hahn YS. Hepatocyte-derived exosomes promote T follicular regulatory cell expansion during HCV infection. Hepatology. 2017 Jul 27. PMID: 28749570.
      View in: PubMed
    4. Wang Y, Singh NK, Spear TT, Hellman LM, Piepenbrink KH, McMahan RH, Rosen HR, Vander Kooi CW, Nishimura MI, Baker BM. How an alloreactive T-cell receptor achieves peptide and MHC specificity. Proc Natl Acad Sci U S A. 2017 Jun 13; 114(24):E4792-E4801. PMID: 28572406.
      View in: PubMed
    5. Golden-Mason L, Rosen HR. Galectin-9: Diverse roles in hepatic immune homeostasis and inflammation. Hepatology. 2017 Jul; 66(1):271-279. PMID: 28195343.
      View in: PubMed
    6. Kalra A, Wedd JP, Bambha KM, Gralla J, Golden-Mason L, Collins C, Rosen HR, Biggins SW. Neutrophil-to-lymphocyte ratio correlates with proinflammatory neutrophils and predicts death in low model for end-stage liver disease patients with cirrhosis. Liver Transpl. 2017 Feb; 23(2):155-165. PMID: 28006875.
      View in: PubMed
    7. Giugliano S, Petroff MG, Warren BD, Jasti S, Linscheid C, Ward A, Kramer A, Dobrinskikh E, Sheiko MA, Gale M, Golden-Mason L, Winn VD, Rosen HR. Correction: Hepatitis C Virus Sensing by Human Trophoblasts Induces Innate Immune Responses and Recruitment of Maternal NK Cells: Potential Implications for Limiting Vertical Transmission. J Immunol. 2017 Jan 15; 198(2):972. PMID: 28069758.
      View in: PubMed
    8. McMahan RH, Porsche CE, Edwards MG, Rosen HR. Correction: Free Fatty Acids Differentially Downregulate Chemokines in Liver Sinusoidal Endothelial Cells: Insights into Non-Alcoholic Fatty Liver Disease. PLoS One. 2016; 11(12):e0168301. PMID: 27930747.
      View in: PubMed
    9. McGettigan BM, McMahan RH, Luo Y, Wang XX, Orlicky DJ, Porsche C, Levi M, Rosen HR. Sevelamer Improves Steatohepatitis, Inhibits Liver and Intestinal Farnesoid X Receptor (FXR), and Reverses Innate Immune Dysregulation in a Mouse Model of Non-alcoholic Fatty Liver Disease. J Biol Chem. 2016 Oct 28; 291(44):23058-23067. PMID: 27605663.
      View in: PubMed
    10. McMahan RH, Porsche CE, Edwards MG, Rosen HR. Free Fatty Acids Differentially Downregulate Chemokines in Liver Sinusoidal Endothelial Cells: Insights into Non-Alcoholic Fatty Liver Disease. PLoS One. 2016; 11(7):e0159217. PMID: 27454769; PMCID: PMC4959750.
    11. Laskey HL, Schomaker N, Hung KW, Asrani SK, Jennings L, Nydam TL, Gralla J, Wiseman A, Rosen HR, Biggins SW. Predicting renal recovery after liver transplant with severe pretransplant subacute kidney injury: The impact of warm ischemia time. Liver Transpl. 2016 Aug; 22(8):1085-91. PMID: 27302834.
      View in: PubMed
    12. White JT, Cross EW, Burchill MA, Danhorn T, McCarter MD, Rosen HR, O'Connor B, Kedl RM. Virtual memory T cells develop and mediate bystander protective immunity in an IL-15-dependent manner. Nat Commun. 2016 Apr 21; 7:11291. PMID: 27097762; PMCID: PMC4844673.
    13. Spear TT, Riley TP, Lyons GE, Callender GG, Roszkowski JJ, Wang Y, Simms PE, Scurti GM, Foley KC, Murray DC, Hellman LM, McMahan RH, Iwashima M, Garrett-Mayer E, Rosen HR, Baker BM, Nishimura MI. Hepatitis C virus-cross-reactive TCR gene-modified T cells: a model for immunotherapy against diseases with genomic instability. J Leukoc Biol. 2016 Sep; 100(3):545-57. PMID: 26921345; PMCID: PMC4982612 [Available on 09/01/17].
    14. Goh CC, Roggerson KM, Lee HC, Golden-Mason L, Rosen HR, Hahn YS. Hepatitis C Virus-Induced Myeloid-Derived Suppressor Cells Suppress NK Cell IFN-? Production by Altering Cellular Metabolism via Arginase-1. J Immunol. 2016 Mar 01; 196(5):2283-92. PMID: 26826241; PMCID: PMC4761460 [Available on 03/01/17].
    15. Sheiko MA, Golden-Mason L, Giugliano S, Hurtado CW, Mack CL, Narkewicz MR, Rosen HR. CD4+ and CD8+ T Cell Activation in Children with Hepatitis C. J Pediatr. 2016 Mar; 170:142-8.e1. PMID: 26743497; PMCID: PMC4833455 [Available on 03/01/17].
    16. Nordstrom EM, Biggins SW, Gralla J, Rosen HR, Everson GT, Burton JR. Consensus Interferon for Recurrent Hepatitis C Infection in Nonresponders to Peginterferon and Ribavirin After Liver Transplant. Exp Clin Transplant. 2015 Dec; 13(6):543-9. PMID: 26643674.
      View in: PubMed
    17. Rosen HR, Golden-Mason L, Daly AK, Yang I, Day CP. Variants in the LGALS9 Gene Are Associated With Development of Liver Disease in Heavy Consumers of Alcohol. Clin Gastroenterol Hepatol. 2016 May; 14(5):762-8.e1. PMID: 26598225.
      View in: PubMed
    18. Hung K, Gralla J, Dodge JL, Bambha KM, Dirchwolf M, Rosen HR, Biggins SW. Optimizing repeat liver transplant graft utility through strategic matching of donor and recipient characteristics. Liver Transpl. 2015 Nov; 21(11):1365-73. PMID: 25865434.
      View in: PubMed
    19. Rosen HR, Biggins SW, Niki T, Gralla J, Hillman H, Hirashima M, Schilsky M, Lee WM. Association Between Plasma Level of Galectin-9 and Survival of Patients With Drug-Induced Acute Liver Failure. Clin Gastroenterol Hepatol. 2016 Apr; 14(4):606-612.e3. PMID: 26499927.
      View in: PubMed
    20. Harwood NM, Golden-Mason L, Cheng L, Rosen HR, Mengshol JA. HCV-infected cells and differentiation increase monocyte immunoregulatory galectin-9 production. J Leukoc Biol. 2016 Mar; 99(3):495-503. PMID: 26475932.
      View in: PubMed
    21. Burchill MA, Golden-Mason L, Wind-Rotolo M, Rosen HR. Memory re-differentiation and reduced lymphocyte activation in chronic HCV-infected patients receiving direct-acting antivirals. J Viral Hepat. 2015 Dec; 22(12):983-91. PMID: 26482547.
      View in: PubMed
    22. Giugliano S, Petroff MG, Warren BD, Jasti S, Linscheid C, Ward A, Kramer A, Dobrinskikh E, Sheiko MA, Gale M, Golden-Mason L, Winn VD, Rosen HR. Hepatitis C Virus Sensing by Human Trophoblasts Induces Innate Immune Responses and Recruitment of Maternal NK Cells: Potential Implications for Limiting Vertical Transmission. J Immunol. 2015 Oct 15; 195(8):3737-47. PMID: 26342030; PMCID: PMC4592818 [Available on 10/15/16].
    23. Dirchwolf M, Dodge JL, Gralla J, Bambha KM, Nydam T, Hung KW, Rosen HR, Feng S, Terrault NA, Biggins SW. The corrected donor age for hepatitis C virus-infected liver transplant recipients. Liver Transpl. 2015 Aug; 21(8):1022-30. PMID: 26074140; PMCID: PMC4809736.
    24. Golden-Mason L, Waasdorp Hurtado CE, Cheng L, Rosen HR. Hepatitis C viral infection is associated with activated cytolytic natural killer cells expressing high levels of T cell immunoglobulin- and mucin-domain-containing molecule-3. Clin Immunol. 2015 May; 158(1):114-25. PMID: 25797693.
      View in: PubMed
    25. Mitchell AM, Stone AE, Cheng L, Ballinger K, Edwards MG, Stoddard M, Li H, Golden-Mason L, Shaw GM, Khetani S, Rosen HR. Transmitted/founder hepatitis C viruses induce cell-type- and genotype-specific differences in innate signaling within the liver. MBio. 2015 Feb 24; 6(2):e02510. PMID: 25714713; PMCID: PMC4357998.
    26. Giugliano S, Kriss M, Golden-Mason L, Dobrinskikh E, Stone AE, Soto-Gutierrez A, Mitchell A, Khetani SR, Yamane D, Stoddard M, Li H, Shaw GM, Edwards MG, Lemon SM, Gale M, Shah VH, Rosen HR. Hepatitis C virus infection induces autocrine interferon signaling by human liver endothelial cells and release of exosomes, which inhibits viral replication. Gastroenterology. 2015 Feb; 148(2):392-402.e13. PMID: 25447848; PMCID: PMC4765499.
    27. Biggins SW, Gralla J, Dodge JL, Bambha KM, Tong S, Barón AE, Inadomi J, Terrault N, Rosen HR. Survival benefit of repeat liver transplantation in the United States: a serial MELD analysis by hepatitis C status and donor risk index. Am J Transplant. 2014 Nov; 14(11):2588-94. PMID: 25243648; PMCID: PMC4205189.
    28. Golden-Mason L, Hahn YS, Strong M, Cheng L, Rosen HR. Extracellular HCV-core protein induces an immature regulatory phenotype in NK cells: implications for outcome of acute infection. PLoS One. 2014; 9(7):e103219. PMID: 25076408; PMCID: PMC4116173.
    29. Stone AE, Mitchell A, Brownell J, Miklin DJ, Golden-Mason L, Polyak SJ, Gale MJ, Rosen HR. Hepatitis C virus core protein inhibits interferon production by a human plasmacytoid dendritic cell line and dysregulates interferon regulatory factor-7 and signal transducer and activator of transcription (STAT) 1 protein expression. PLoS One. 2014; 9(5):e95627. PMID: 24788809; PMCID: PMC4006833.
    30. Ishimoto T, Lanaspa MA, Rivard CJ, Roncal-Jimenez CA, Orlicky DJ, Cicerchi C, McMahan RH, Abdelmalek MF, Rosen HR, Jackman MR, MacLean PS, Diggle CP, Asipu A, Inaba S, Kosugi T, Sato W, Maruyama S, Sánchez-Lozada LG, Sautin YY, Hill JO, Bonthron DT, Johnson RJ. High-fat and high-sucrose (western) diet induces steatohepatitis that is dependent on fructokinase. Hepatology. 2013 Nov; 58(5):1632-43. PMID: 23813872; PMCID: PMC3894259.
    31. Rosen HR. Emerging concepts in immunity to hepatitis C virus infection. J Clin Invest. 2013 Oct; 123(10):4121-30. PMID: 24084744; PMCID: PMC3784533.
    32. Golden-Mason L, Rosen HR. Natural killer cells: multifaceted players with key roles in hepatitis C immunity. Immunol Rev. 2013 Sep; 255(1):68-81. PMID: 23947348; PMCID: PMC3765000.
    33. Brownell J, Wagoner J, Lovelace ES, Thirstrup D, Mohar I, Smith W, Giugliano S, Li K, Crispe IN, Rosen HR, Polyak SJ. Independent, parallel pathways to CXCL10 induction in HCV-infected hepatocytes. J Hepatol. 2013 Oct; 59(4):701-8. PMID: 23770038; PMCID: PMC3779522.
    34. Stone AE, Giugliano S, Schnell G, Cheng L, Leahy KF, Golden-Mason L, Gale M, Rosen HR. Hepatitis C virus pathogen associated molecular pattern (PAMP) triggers production of lambda-interferons by human plasmacytoid dendritic cells. PLoS Pathog. 2013; 9(4):e1003316. PMID: 23637605; PMCID: PMC3630164.
    35. Lee HC, Sung SS, Krueger PD, Jo YA, Rosen HR, Ziegler SF, Hahn YS. Hepatitis C virus promotes T-helper (Th)17 responses through thymic stromal lymphopoietin production by infected hepatocytes. Hepatology. 2013 Apr; 57(4):1314-24. PMID: 23150092; PMCID: PMC3582737.
    36. Yanagisawa K, Yue S, van der Vliet HJ, Wang R, Alatrakchi N, Golden-Mason L, Schuppan D, Koziel MJ, Rosen HR, Exley MA. Ex vivo analysis of resident hepatic pro-inflammatory CD1d-reactive T cells and hepatocyte surface CD1d expression in hepatitis C. J Viral Hepat. 2013 Aug; 20(8):556-65. PMID: 23808994; PMCID: PMC4054599.
    37. McMahan RH, Wang XX, Cheng LL, Krisko T, Smith M, El Kasmi K, Pruzanski M, Adorini L, Golden-Mason L, Levi M, Rosen HR. Bile acid receptor activation modulates hepatic monocyte activity and improves nonalcoholic fatty liver disease. J Biol Chem. 2013 Apr 26; 288(17):11761-70. PMID: 23460643; PMCID: PMC3636865.
    38. Duggal P, Thio CL, Wojcik GL, Goedert JJ, Mangia A, Latanich R, Kim AY, Lauer GM, Chung RT, Peters MG, Kirk GD, Mehta SH, Cox AL, Khakoo SI, Alric L, Cramp ME, Donfield SM, Edlin BR, Tobler LH, Busch MP, Alexander G, Rosen HR, Gao X, Abdel-Hamid M, Apps R, Carrington M, Thomas DL. Genome-wide association study of spontaneous resolution of hepatitis C virus infection: data from multiple cohorts. Ann Intern Med. 2013 Feb 19; 158(4):235-45. PMID: 23420232; PMCID: PMC3638215.
    39. Golden-Mason L, McMahan RH, Strong M, Reisdorph R, Mahaffey S, Palmer BE, Cheng L, Kulesza C, Hirashima M, Niki T, Rosen HR. Galectin-9 functionally impairs natural killer cells in humans and mice. J Virol. 2013 May; 87(9):4835-45. PMID: 23408620; PMCID: PMC3624298.
    40. Biggins SW, Trotter J, Gralla J, Burton JR, Bambha KM, Dodge J, Brocato M, Cheng L, McQueen M, Forman L, Chang M, Kam I, Everson G, Spritz RA, Klintmalm G, Rosen HR. Differential effects of donor and recipient IL28B and DDX58 SNPs on severity of HCV after liver transplantation. J Hepatol. 2013 May; 58(5):969-76. PMID: 23333445; PMCID: PMC3878646.
    41. Biggins SW, Bambha KM, Terrault NA, Inadomi J, Shiboski S, Dodge JL, Gralla J, Rosen HR, Roberts JP. Projected future increase in aging hepatitis C virus-infected liver transplant candidates: a potential effect of hepatocellular carcinoma. Liver Transpl. 2012 Dec; 18(12):1471-8. PMID: 23008049; PMCID: PMC3518670.
    42. Golden-Mason L, Stone AE, Bambha KM, Cheng L, Rosen HR. Race- and gender-related variation in natural killer p46 expression associated with differential anti-hepatitis C virus immunity. Hepatology. 2012 Oct; 56(4):1214-22. PMID: 22505144; PMCID: PMC3458134.
    43. Barjon C, Niki T, Vérillaud B, Opolon P, Bedossa P, Hirashima M, Blanchin S, Wassef M, Rosen HR, Jimenez AS, Wei M, Busson P. A novel monoclonal antibody for detection of galectin-9 in tissue sections: application to human tissues infected by oncogenic viruses. Infect Agent Cancer. 2012 Jul 17; 7(1):16. PMID: 22805533; PMCID: PMC3464730.
    44. Tacke RS, Lee HC, Goh C, Courtney J, Polyak SJ, Rosen HR, Hahn YS. Myeloid suppressor cells induced by hepatitis C virus suppress T-cell responses through the production of reactive oxygen species. Hepatology. 2012 Feb; 55(2):343-53. PMID: 21953144; PMCID: PMC3358038.
    45. Rutebemberwa A, Rosen HR. Of mice and men, calcineurin inhibitors and hepatitis C. Liver Transpl. 2012 Jan; 18(1):1-4. PMID: 22034173.
      View in: PubMed
    46. Foster RG, Golden-Mason L, Rutebemberwa A, Rosen HR. Interleukin (IL)-17/IL-22-producing T cells enriched within the liver of patients with chronic hepatitis C viral (HCV) infection. Dig Dis Sci. 2012 Feb; 57(2):381-9. PMID: 22183819.
      View in: PubMed
    47. Shang S, Plymoth A, Ge S, Feng Z, Rosen HR, Sangrajrang S, Hainaut P, Marrero JA, Beretta L. Identification of osteopontin as a novel marker for early hepatocellular carcinoma. Hepatology. 2012 Feb; 55(2):483-90. PMID: 21953299; PMCID: PMC3914762.
    48. Golden-Mason L, Bambha KM, Cheng L, Howell CD, Taylor MW, Clark PJ, Afdhal N, Rosen HR. Natural killer inhibitory receptor expression associated with treatment failure and interleukin-28B genotype in patients with chronic hepatitis C. Hepatology. 2011 Nov; 54(5):1559-69. PMID: 21983945; PMCID: PMC3206734.
    49. Rosen HR. Clinical practice. Chronic hepatitis C infection. N Engl J Med. 2011 Jun 23; 364(25):2429-38. PMID: 21696309.
      View in: PubMed
    50. Yang L, Rudser KD, Higgins L, Rosen HR, Zaman A, Corless CL, David L, Gourley GR. Novel biomarker candidates to predict hepatic fibrosis in hepatitis C identified by serum proteomics. Dig Dis Sci. 2011 Nov; 56(11):3305-15. PMID: 21590334; PMCID: PMC3181275.
    51. Li H, Hughes AL, Bano N, McArdle S, Livingston S, Deubner H, McMahon BJ, Townshend-Bulson L, McMahan R, Rosen HR, Gretch DR. Genetic diversity of near genome-wide hepatitis C virus sequences during chronic infection: evidence for protein structural conservation over time. PLoS One. 2011 May 05; 6(5):e19562. PMID: 21573177; PMCID: PMC3088699.
    52. Benson AB, Burton JR, Austin GL, Biggins SW, Zimmerman MA, Kam I, Mandell S, Silliman CC, Rosen H, Moss M. Differential effects of plasma and red blood cell transfusions on acute lung injury and infection risk following liver transplantation. Liver Transpl. 2011 Feb; 17(2):149-58. PMID: 21280188; PMCID: PMC3399914.
    53. McMahan RH, Golden-Mason L, Nishimura MI, McMahon BJ, Kemper M, Allen TM, Gretch DR, Rosen HR. Tim-3 expression on PD-1+ HCV-specific human CTLs is associated with viral persistence, and its blockade restores hepatocyte-directed in vitro cytotoxicity. J Clin Invest. 2010 Dec; 120(12):4546-57. PMID: 21084749; PMCID: PMC2994339.
    54. Golden-Mason L, Cox AL, Randall JA, Cheng L, Rosen HR. Increased natural killer cell cytotoxicity and NKp30 expression protects against hepatitis C virus infection in high-risk individuals and inhibits replication in vitro. Hepatology. 2010 Nov; 52(5):1581-9. PMID: 20812318; PMCID: PMC2967665.
    55. Hurtado CW, Golden-Mason L, Brocato M, Krull M, Narkewicz MR, Rosen HR. Innate immune function in placenta and cord blood of hepatitis C--seropositive mother-infant dyads. PLoS One. 2010 Aug 30; 5(8):e12232. PMID: 20814429; PMCID: PMC2923602.
    56. Benson AB, Austin GL, Berg M, McFann KK, Thomas S, Ramirez G, Rosen H, Silliman CC, Moss M. Transfusion-related acute lung injury in ICU patients admitted with gastrointestinal bleeding. Intensive Care Med. 2010 Oct; 36(10):1710-7. PMID: 20658125; PMCID: PMC3727900.
    57. Mosbruger TL, Duggal P, Goedert JJ, Kirk GD, Hoots WK, Tobler LH, Busch M, Peters MG, Rosen HR, Thomas DL, Thio CL. Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus. J Infect Dis. 2010 May 01; 201(9):1371-80. PMID: 20331378; PMCID: PMC2853721.
    58. Tang X, Wagoner J, Negash A, Austin M, McLauchlan J, Hahn YS, Rosen HR, Polyak SJ. Functional characterization of core genes from patients with acute hepatitis C virus infection. J Infect Dis. 2010 Mar 15; 201(6):912-22. PMID: 20170366; PMCID: PMC2827820.
    59. Mengshol JA, Golden-Mason L, Arikawa T, Smith M, Niki T, McWilliams R, Randall JA, McMahan R, Zimmerman MA, Rangachari M, Dobrinskikh E, Busson P, Polyak SJ, Hirashima M, Rosen HR. A crucial role for Kupffer cell-derived galectin-9 in regulation of T cell immunity in hepatitis C infection. PLoS One. 2010 Mar 04; 5(3):e9504. PMID: 20209097; PMCID: PMC2831996.
    60. Eberlein J, Nguyen TT, Victorino F, Golden-Mason L, Rosen HR, Homann D. Comprehensive assessment of chemokine expression profiles by flow cytometry. J Clin Invest. 2010 Mar; 120(3):907-23. PMID: 20197626; PMCID: PMC2827956.
    61. Neumann-Haefelin C, Timm J, Schmidt J, Kersting N, Fitzmaurice K, Oniangue-Ndza C, Kemper MN, Humphreys I, McKiernan S, Kelleher D, Lohmann V, Bowness P, Huzly D, Rosen HR, Kim AY, Lauer GM, Allen TM, Barnes E, Roggendorf M, Blum HE, Thimme R. Protective effect of human leukocyte antigen B27 in hepatitis C virus infection requires the presence of a genotype-specific immunodominant CD8+ T-cell epitope. Hepatology. 2010 Jan; 51(1):54-62. PMID: 20034048; PMCID: PMC4396188.
    62. McMahon BJ, Bruden D, Bruce MG, Livingston S, Christensen C, Homan C, Hennessy TW, Williams J, Sullivan D, Rosen HR, Gretch D. Adverse outcomes in Alaska natives who recovered from or have chronic hepatitis C infection. Gastroenterology. 2010 Mar; 138(3):922-31.e1. PMID: 19909749.
      View in: PubMed
    63. Hughes MG, Rosen HR. Human liver transplantation as a model to study hepatitis C virus pathogenesis. Liver Transpl. 2009 Nov; 15(11):1395-411. PMID: 19877210; PMCID: PMC2954677.
    64. Thomas DL, Thio CL, Martin MP, Qi Y, Ge D, O'Huigin C, Kidd J, Kidd K, Khakoo SI, Alexander G, Goedert JJ, Kirk GD, Donfield SM, Rosen HR, Tobler LH, Busch MP, McHutchison JG, Goldstein DB, Carrington M. Genetic variation in IL28B and spontaneous clearance of hepatitis C virus. Nature. 2009 Oct 08; 461(7265):798-801. PMID: 19759533; PMCID: PMC3172006.
    65. Golden-Mason L, Palmer BE, Kassam N, Townshend-Bulson L, Livingston S, McMahon BJ, Castelblanco N, Kuchroo V, Gretch DR, Rosen HR. Negative immune regulator Tim-3 is overexpressed on T cells in hepatitis C virus infection and its blockade rescues dysfunctional CD4+ and CD8+ T cells. J Virol. 2009 Sep; 83(18):9122-30. PMID: 19587053; PMCID: PMC2738247.
    66. Cummings KL, Rosen HR, Hahn YS. Frequency of gC1qR+CD4+ T cells increases during acute hepatitis C virus infection and remains elevated in patients with chronic infection. Clin Immunol. 2009 Sep; 132(3):401-11. PMID: 19473882; PMCID: PMC2720442.
    67. Mengshol JA, Golden-Mason L, Castelblanco N, Im KA, Dillon SM, Wilson CC, Rosen HR. Impaired plasmacytoid dendritic cell maturation and differential chemotaxis in chronic hepatitis C virus: associations with antiviral treatment outcomes. Gut. 2009 Jul; 58(7):964-73. PMID: 19193669; PMCID: PMC2689392.
    68. Dazert E, Neumann-Haefelin C, Bressanelli S, Fitzmaurice K, Kort J, Timm J, McKiernan S, Kelleher D, Gruener N, Tavis JE, Rosen HR, Shaw J, Bowness P, Blum HE, Klenerman P, Bartenschlager R, Thimme R. Loss of viral fitness and cross-recognition by CD8+ T cells limit HCV escape from a protective HLA-B27-restricted human immune response. J Clin Invest. 2009 Feb; 119(2):376-86. PMID: 19139562; PMCID: PMC2631298.
    69. Cox AL, Page K, Bruneau J, Shoukry NH, Lauer GM, Kim AY, Rosen HR, Radziewicz H, Grakoui A, Fierer DS, Branch AD, Kaplan DE, Chang KM. Rare birds in North America: acute hepatitis C cohorts. Gastroenterology. 2009 Jan; 136(1):26-31. PMID: 19059257; PMCID: PMC4143376.
    70. Kuntzen T, Timm J, Berical A, Lennon N, Berlin AM, Young SK, Lee B, Heckerman D, Carlson J, Reyor LL, Kleyman M, McMahon CM, Birch C, Schulze Zur Wiesch J, Ledlie T, Koehrsen M, Kodira C, Roberts AD, Lauer GM, Rosen HR, Bihl F, Cerny A, Spengler U, Liu Z, Kim AY, Xing Y, Schneidewind A, Madey MA, Fleckenstein JF, Park VM, Galagan JE, Nusbaum C, Walker BD, Lake-Bakaar GV, Daar ES, Jacobson IM, Gomperts ED, Edlin BR, Donfield SM, Chung RT, Talal AH, Marion T, Birren BW, Henn MR, Allen TM. Naturally occurring dominant resistance mutations to hepatitis C virus protease and polymerase inhibitors in treatment-naïve patients. Hepatology. 2008 Dec; 48(6):1769-78. PMID: 19026009; PMCID: PMC2645896.
    71. Pandey JP, Namboodiri AM, Luo Y, Wu Y, Elston RC, Thomas DL, Rosen HR, Goedert JJ. Genetic markers of IgG influence the outcome of infection with hepatitis C virus. J Infect Dis. 2008 Nov 01; 198(9):1334-6. PMID: 18855559; PMCID: PMC2677690.
    72. Yee LJ, Im K, Wahed AS, Bugawan T, Li J, Rhodes SL, Erlich H, Rosen HR, Liang TJ, Yang H. Polymorphism in the human major histocompatibility complex and early viral decline during treatment of chronic hepatitis C. Antimicrob Agents Chemother. 2009 Feb; 53(2):615-21. PMID: 18852273; PMCID: PMC2630649.
    73. Burton JR, Klarquist J, Im K, Smyk-Pearson S, Golden-Mason L, Castelblanco N, Terrault N, Rosen HR. Prospective analysis of effector and regulatory CD4+ T cells in chronic HCV patients undergoing combination antiviral therapy. J Hepatol. 2008 Sep; 49(3):329-38. PMID: 18644644.
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    74. Su X, Yee LJ, Im K, Rhodes SL, Tang Y, Tong X, Howell C, Ramcharran D, Rosen HR, Taylor MW, Liang TJ, Yang H. Association of single nucleotide polymorphisms in interferon signaling pathway genes and interferon-stimulated genes with the response to interferon therapy for chronic hepatitis C. J Hepatol. 2008 Aug; 49(2):184-91. PMID: 18571276; PMCID: PMC2609954.
    75. Rosen HR. Transplantation immunology: what the clinician needs to know for immunotherapy. Gastroenterology. 2008 May; 134(6):1789-801. PMID: 18471555.
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    76. Rhodes SL, Erlich H, Im KA, Wang J, Li J, Bugawan T, Jeffers L, Tong X, Su X, Rosen HR, Yee LJ, Liang TJ, Yang H. Associations between the human MHC and sustained virologic response in the treatment of chronic hepatitis C virus infection. Genes Immun. 2008 Jun; 9(4):328-33. PMID: 18418397; PMCID: PMC2696808.
    77. Golden-Mason L, Klarquist J, Wahed AS, Rosen HR. Cutting edge: programmed death-1 expression is increased on immunocytes in chronic hepatitis C virus and predicts failure of response to antiviral therapy: race-dependent differences. J Immunol. 2008 Mar 15; 180(6):3637-41. PMID: 18322167.
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    78. Smyk-Pearson S, Golden-Mason L, Klarquist J, Burton JR, Tester IA, Wang CC, Culbertson N, Vandenbark AA, Rosen HR. Functional suppression by FoxP3+CD4+CD25(high) regulatory T cells during acute hepatitis C virus infection. J Infect Dis. 2008 Jan 01; 197(1):46-57. PMID: 18171284.
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    79. Rosen HR, Doherty DG, Madrigal-Estebas L, O'Farrelly C, Golden-Mason L. Pretransplantation CD56(+) innate lymphocyte populations associated with severity of hepatitis C virus recurrence. Liver Transpl. 2008 Jan; 14(1):31-40. PMID: 18161829.
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    80. Smyk-Pearson S, Tester IA, Klarquist J, Palmer BE, Pawlotsky JM, Golden-Mason L, Rosen HR. Spontaneous recovery in acute human hepatitis C virus infection: functional T-cell thresholds and relative importance of CD4 help. J Virol. 2008 Feb; 82(4):1827-37. PMID: 18045940; PMCID: PMC2258714.
    81. Mengshol JA, Golden-Mason L, Rosen HR. Mechanisms of Disease: HCV-induced liver injury. Nat Clin Pract Gastroenterol Hepatol. 2007 Nov; 4(11):622-34. PMID: 17978819.
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    82. Wang CC, Krantz E, Klarquist J, Krows M, McBride L, Scott EP, Shaw-Stiffel T, Weston SJ, Thiede H, Wald A, Rosen HR. Acute hepatitis C in a contemporary US cohort: modes of acquisition and factors influencing viral clearance. J Infect Dis. 2007 Nov 15; 196(10):1474-82. PMID: 18008226.
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    83. Rosen HR. Liver retransplantation for hepatitis C: seeing is believing. Liver Transpl. 2007 Sep; 13(9):1217-8. PMID: 17763404.
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    84. Rosen HR, Weston SJ, Im K, Yang H, Burton JR, Erlich H, Klarquist J, Belle SH. Selective decrease in hepatitis C virus-specific immunity among African Americans and outcome of antiviral therapy. Hepatology. 2007 Aug; 46(2):350-8. PMID: 17659573.
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    85. Arjal RR, Burton JR, Villamil F, Rosen HR. Review article: the treatment of hepatitis C virus recurrence after liver transplantation. Aliment Pharmacol Ther. 2007 Jul 15; 26(2):127-40. PMID: 17593060.
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    86. Xie SX, Forman MS, Farmer J, Moore P, Wang Y, Wang X, Clark CM, Coslett HB, Chatterjee A, Arnold SE, Rosen H, Karlawish JH, Van Deerlin VM, Lee VM, Trojanowski JQ, Grossman M. Factors associated with survival probability in autopsy-proven frontotemporal lobar degeneration. J Neurol Neurosurg Psychiatry. 2008 Feb; 79(2):126-9. PMID: 17615171.
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    87. Golden-Mason L, Palmer B, Klarquist J, Mengshol JA, Castelblanco N, Rosen HR. Upregulation of PD-1 expression on circulating and intrahepatic hepatitis C virus-specific CD8+ T cells associated with reversible immune dysfunction. J Virol. 2007 Sep; 81(17):9249-58. PMID: 17567698; PMCID: PMC1951397.
    88. Golden-Mason L, Castelblanco N, O'Farrelly C, Rosen HR. Phenotypic and functional changes of cytotoxic CD56pos natural T cells determine outcome of acute hepatitis C virus infection. J Virol. 2007 Sep; 81(17):9292-8. PMID: 17553896; PMCID: PMC1951454.
    89. Holzer B, Rosen HR, Novi G, Ausch C, Hölbling N, Schiessel R. Sacral nerve stimulation for neurogenic faecal incontinence. Br J Surg. 2007 Jun; 94(6):749-53. PMID: 17410558.
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    90. Wertheimer AM, Polyak SJ, Leistikow R, Rosen HR. Engulfment of apoptotic cells expressing HCV proteins leads to differential chemokine expression and STAT signaling in human dendritic cells. Hepatology. 2007 Jun; 45(6):1422-32. PMID: 17538964.
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    91. Zaman A, Rosen HR, Ingram K, Corless CL, Oh E, Smith K. Assessment of FIBROSpect II to detect hepatic fibrosis in chronic hepatitis C patients. Am J Med. 2007 Mar; 120(3):280.e9-14. PMID: 17349453.
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    92. Huang Y, Yang H, Borg BB, Su X, Rhodes SL, Yang K, Tong X, Tang G, Howell CD, Rosen HR, Thio CL, Thomas DL, Alter HJ, Sapp RK, Liang TJ. A functional SNP of interferon-gamma gene is important for interferon-alpha-induced and spontaneous recovery from hepatitis C virus infection. Proc Natl Acad Sci U S A. 2007 Jan 16; 104(3):985-90. PMID: 17215375; PMCID: PMC1783426.
    93. Rosen H, Glukmann V, Feldmann T, Fridman E, Lichtstein D. Short-term effects of cardiac steroids on intracellular membrane traffic in neuronal NT2 cells. Cell Mol Biol (Noisy-le-grand). 2006 Dec 30; 52(8):78-86. PMID: 17535740.
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    94. Golden-Mason L, Burton JR, Castelblanco N, Klarquist J, Benlloch S, Wang C, Rosen HR. Loss of IL-7 receptor alpha-chain (CD127) expression in acute HCV infection associated with viral persistence. Hepatology. 2006 Nov; 44(5):1098-109. PMID: 17058243.
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    95. Burton JR, Rosen HR. Acute rejection in HCV-infected liver transplant recipients: The great conundrum. Liver Transpl. 2006 Nov; 12(11 Suppl 2):S38-47. PMID: 17051562.
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    96. Van Kleek EJ, Schwartz JM, Rayhill SC, Rosen HR, Cotler SJ. Liver transplantation for hepatocellular carcinoma: a survey of practices. J Clin Gastroenterol. 2006 Aug; 40(7):643-7. PMID: 16917411.
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    97. Smyk-Pearson S, Tester IA, Lezotte D, Sasaki AW, Lewinsohn DM, Rosen HR. Differential antigenic hierarchy associated with spontaneous recovery from hepatitis C virus infection: implications for vaccine design. J Infect Dis. 2006 Aug 15; 194(4):454-63. PMID: 16845628.
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    98. Burton JR, Rosen HR. Treatment of HCV recurrence: do the pretransplantation rules apply? Liver Transpl. 2006 Jul; 12(7):1044-8. PMID: 16799952.
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    99. Burton JR, Rosen HR. Diagnosis and management of allograft failure. Clin Liver Dis. 2006 May; 10(2):407-35, x. PMID: 16971269.
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    100. Callender GG, Rosen HR, Roszkowski JJ, Lyons GE, Li M, Moore T, Brasic N, McKee MD, Nishimura MI. Identification of a hepatitis C virus-reactive T cell receptor that does not require CD8 for target cell recognition. Hepatology. 2006 May; 43(5):973-81. PMID: 16628627.
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    101. Golden-Mason L, Rosen HR. Natural killer cells: primary target for hepatitis C virus immune evasion strategies? Liver Transpl. 2006 Mar; 12(3):363-72. PMID: 16498647.
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    102. Burton JR, Rosen HR. Liver retransplantation for hepatitis C virus recurrence: a survey of liver transplant programs in the United States. Clin Gastroenterol Hepatol. 2005 Jul; 3(7):700-4. PMID: 16206504.
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    103. Tester I, Smyk-Pearson S, Wang P, Wertheimer A, Yao E, Lewinsohn DM, Tavis JE, Rosen HR. Immune evasion versus recovery after acute hepatitis C virus infection from a shared source. J Exp Med. 2005 Jun 06; 201(11):1725-31. PMID: 15939788; PMCID: PMC2213272.
    104. Martinez OM, Rosen HR. Basic concepts in transplant immunology. Liver Transpl. 2005 Apr; 11(4):370-81. PMID: 15776458.
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    105. Weston SJ, Leistikow RL, Reddy KR, Torres M, Wertheimer AM, Lewinsohn DM, Chou S, Davey MP, Corless C, O'Farrelly C, Nelson DR, Rosen HR. Reconstitution of hepatitis C virus-specific T-cellmediated immunity after liver transplantation. Hepatology. 2005 Jan; 41(1):72-81. PMID: 15619226.
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    106. Burton JR, Rosen HR. Retransplantation for hepatitis C: what do we really know? Liver Transpl. 2004 Dec; 10(12):1504-6. PMID: 15558586.
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    107. Cabrera R, Tu Z, Xu Y, Firpi RJ, Rosen HR, Liu C, Nelson DR. An immunomodulatory role for CD4(+)CD25(+) regulatory T lymphocytes in hepatitis C virus infection. Hepatology. 2004 Nov; 40(5):1062-71. PMID: 15486925.
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    108. Rosen HR, Hinrichs DJ, Leistikow RL, Callender G, Wertheimer AM, Nishimura MI, Lewinsohn DM. Cutting edge: identification of hepatitis C virus-specific CD8+ T cells restricted by donor HLA alleles following liver transplantation. J Immunol. 2004 Nov 01; 173(9):5355-9. PMID: 15494481.
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    109. Burton JR, Sonnenberg A, Rosen HR. Retransplantation for recurrent hepatitis C in the MELD era: maximizing utility. Liver Transpl. 2004 Oct; 10(10 Suppl 2):S59-64. PMID: 15382221.
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    110. Wertheimer AM, Bakke A, Rosen HR. Direct enumeration and functional assessment of circulating dendritic cells in patients with liver disease. Hepatology. 2004 Aug; 40(2):335-45. PMID: 15368438.
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    111. Austin GL, Sasaki AW, Zaman A, Rabkin JM, Olyaei A, Ruimy R, Orloff SL, Ham J, Rosen HR. Comparative analysis of outcome following liver transplantation in US veterans. Am J Transplant. 2004 May; 4(5):788-95. PMID: 15084176.
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    112. Zaman A, Hapke RJ, Flora K, Rosen HR, Benner KG. Changing compliance to the American College of Gastroenterology guidelines for the management of variceal hemorrhage: a regional survey. Am J Gastroenterol. 2004 Apr; 99(4):645-9. PMID: 15089896.
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    113. Brown RS, Rush SH, Rosen HR, Langnas AN, Klintmalm GB, Hanto DW, Punch JD. Liver and intestine transplantation. Am J Transplant. 2004; 4 Suppl 9:81-92. PMID: 15113357.
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    114. Chan SE, Schwartz JM, Rosen HR. Treatment of hepatitis C in solid organ transplantation. Drugs. 2004; 64(5):489-98. PMID: 14977386.
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    115. Simon BE, Cornell KA, Clark TR, Chou S, Rosen HR, Barry RA. DNA vaccination protects mice against challenge with Listeria monocytogenes expressing the hepatitis C virus NS3 protein. Infect Immun. 2003 Nov; 71(11):6372-80. PMID: 14573658; PMCID: PMC219586.
    116. Rosen HR. Hepatitis C pathogenesis: mechanisms of viral clearance and liver injury. Liver Transpl. 2003 Nov; 9(11):S35-43. PMID: 14586893.
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    117. Gopal DV, Corless CL, Rabkin JM, Olyaei AJ, Rosen HR. Graft failure from severe recurrent primary sclerosing cholangitis following orthotopic liver transplantation. J Clin Gastroenterol. 2003 Oct; 37(4):344-7. PMID: 14506394.
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    118. Chan SE, Rosen HR. Outcome and management of hepatitis C in liver transplant recipients. Clin Infect Dis. 2003 Sep 15; 37(6):807-12. PMID: 12955642.
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    119. Rosen HR, Prieto M, Casanovas-Taltavull T, Cuervas-Mons V, Guckelberger O, Muiesan P, Strong RW, Bechstein WO, O'grady J, Zaman A, Chan B, Berenguer J, Williams R, Heaton N, Neuhaus P. Validation and refinement of survival models for liver retransplantation. Hepatology. 2003 Aug; 38(2):460-9. PMID: 12883491.
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    120. Gopal DV, Rosen HR. Duration of antiviral therapy for cholestatic HCV recurrence may need to be indefinite. Liver Transpl. 2003 Apr; 9(4):348-53. PMID: 12682884.
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    121. Jazrawi SF, Zaman A, Muhammad Z, Rabkin JM, Corless CL, Olyaei A, Biggs A, Ham J, Chou S, Rosen HR. Tumor necrosis factor-alpha promoter polymorphisms and the risk of rejection after liver transplantation: a case control analysis of 210 donor-recipient pairs. Liver Transpl. 2003 Apr; 9(4):377-82. PMID: 12682890.
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    122. Wertheimer AM, Miner C, Lewinsohn DM, Sasaki AW, Kaufman E, Rosen HR. Novel CD4+ and CD8+ T-cell determinants within the NS3 protein in subjects with spontaneously resolved HCV infection. Hepatology. 2003 Mar; 37(3):577-89. PMID: 12601356.
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    123. Rosen HR. Hepatitis C virus in the human liver transplantation model. Clin Liver Dis. 2003 Feb; 7(1):107-25. PMID: 12691461.
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    124. Rosen HR. Hepatitis C in the liver transplant recipient: current understanding and treatment. Microbes Infect. 2002 Oct; 4(12):1253-8. PMID: 12467767.
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    125. Bowman JC, Hicks PS, Kurtz MB, Rosen H, Schmatz DM, Liberator PA, Douglas CM. The antifungal echinocandin caspofungin acetate kills growing cells of Aspergillus fumigatus in vitro. Antimicrob Agents Chemother. 2002 Sep; 46(9):3001-12. PMID: 12183260; PMCID: PMC127409.
    126. Rabkin JM, Rosen HR, Corless CL, Olyaei AJ. Tacrolimus is associated with a lower incidence of cardiovascular complications in liver transplant recipients. Transplant Proc. 2002 Aug; 34(5):1557-8. PMID: 12176483.
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    127. Rosen HR, Marousek G, Chou S. A longitudinal analysis of T-cell epitope-coding regions of hepatitis C virus after liver transplantation. Transplantation. 2002 Jul 27; 74(2):209-16. PMID: 12151733.
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    128. Rosen HR, Schwartz JM. Hepatitis C quasispecies and severity of recurrence: cause, consequence, or coincidence? Liver Transpl. 2002 Jul; 8(7):646-8. PMID: 12089722.
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    129. Rosen HR, Ribeiro RR, Weinberger L, Wolf S, Chung M, Gretch DR, Perelson AS. Early hepatitis C viral kinetics correlate with long-term outcome in patients receiving high dose induction followed by combination interferon and ribavirin therapy. J Hepatol. 2002 Jul; 37(1):124-30. PMID: 12076871.
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    130. Murphy MD, Rosen HR, Marousek GI, Chou S. Analysis of sequence configurations of the ISDR, PKR-binding domain, and V3 region as predictors of response to induction interferon-alpha and ribavirin therapy in chronic hepatitis C infection. Dig Dis Sci. 2002 Jun; 47(6):1195-205. PMID: 12064791.
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    131. Rabkin JM, Corless CL, Rosen HR, Olyaei AJ. Immunosuppression impact on long-term cardiovascular complications after liver transplantation. Am J Surg. 2002 May; 183(5):595-9. PMID: 12034401.
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    132. Biggins SW, Beldecos A, Rabkin JM, Rosen HR. Retransplantation for hepatic allograft failure: prognostic modeling and ethical considerations. Liver Transpl. 2002 Apr; 8(4):313-22. PMID: 11965573.
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    133. Rosen HR, McHutchison JG, Conrad AJ, Lentz JJ, Marousek G, Rose SL, Zaman A, Taylor K, Chou S. Tumor necrosis factor genetic polymorphisms and response to antiviral therapy in patients with chronic hepatitis C. Am J Gastroenterol. 2002 Mar; 97(3):714-20. PMID: 11922568.
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    134. Rosen HR, Fontana RJ, Brown RS, Wiesner RH, Schiano TD, Bass NM, Bloomer JR, Kaplan L. Curricular guidelines for training in transplant hepatology. Liver Transpl. 2002 Jan; 8(1):85-7. PMID: 11799493.
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    135. Rosen HR, Miner C, Sasaki AW, Lewinsohn DM, Conrad AJ, Bakke A, Bouwer HG, Hinrichs DJ. Frequencies of HCV-specific effector CD4+ T cells by flow cytometry: correlation with clinical disease stages. Hepatology. 2002 Jan; 35(1):190-8. PMID: 11786976.
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    136. Rosen HR. Hepatitis B and C in the liver transplant recipient: current understanding and treatment. Liver Transpl. 2001 Nov; 7(11 Suppl 1):S87-98. PMID: 11689781.
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    137. Gruessner U, Clemens M, Pahlplatz PV, Sperling P, Witte J, Rosen HR. Improvement of perineal wound healing by local administration of gentamicin-impregnated collagen fleeces after abdominoperineal excision of rectal cancer. Am J Surg. 2001 Nov; 182(5):502-9. PMID: 11754859.
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    138. Rosen HR, Urbarz C, Holzer B, Novi G, Schiessel R. Sacral nerve stimulation as a treatment for fecal incontinence. Gastroenterology. 2001 Sep; 121(3):536-41. PMID: 11522736.
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    139. Davey MP, Rosen HR, Woody CN, Haley DP, Kurkinen J, Lewinsohn DM. T-cell clones derived by CD3 stimulation from hepatitis C virus explanted liver tissue are not representative of dominant clones present in vivo. Liver Transpl. 2001 Aug; 7(8):716-23. PMID: 11510018.
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    140. Rabkin JM, de La Melena V, Orloff SL, Corless CL, Rosen HR, Olyaei AJ. Late mortality after orthotopic liver transplantation. Am J Surg. 2001 May; 181(5):475-9. PMID: 11448447.
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    141. Gopal DV, Rabkin JM, Berk BS, Corless CL, Chou S, Olyaei A, Orloff SL, Rosen HR. Treatment of progressive hepatitis C recurrence after liver transplantation with combination interferon plus ribavirin. Liver Transpl. 2001 Mar; 7(3):181-90. PMID: 11244158.
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    142. Rabkin JM, Rosen HR, Corless CL, Orloff SL, Olyaei AJ. Prophylactic antiviral therapy in CMV high-risk liver transplant recipients. Transplant Proc. 2001 Feb-Mar; 33(1-2):1811-2. PMID: 11267523.
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    143. Rabkin JM, Corless CL, Rosen HR, Olyaei AJ. Pharmacoeconomic study of tacrolimus-based versus cyclosporine-based immunosuppressive therapy following liver transplantation. Transplant Proc. 2001 Feb-Mar; 33(1-2):1532-4. PMID: 11267411.
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    144. Gralnek IM, Hays RD, Kilbourne A, Rosen HR, Keeffe EB, Artinian L, Kim S, Lazarovici D, Jensen DM, Busuttil RW, Martin P. Development and evaluation of the Liver Disease Quality of Life instrument in persons with advanced, chronic liver disease--the LDQOL 1.0. Am J Gastroenterol. 2000 Dec; 95(12):3552-65. PMID: 11151892.
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    145. Rosen HR. Retransplantation for hepatitis C: implications of different policies. Liver Transpl. 2000 Nov; 6(6 Suppl 2):S41-6. PMID: 11084084.
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    146. Faigel DO, Rosen HR, Sasaki A, Flora K, Benner K. EUS in cirrhotic patients with and without prior variceal hemorrhage in comparison with noncirrhotic control subjects. Gastrointest Endosc. 2000 Oct; 52(4):455-62. PMID: 11023560.
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    147. Rosen HR, Martin P. Viral hepatitis in the liver transplant recipient. Infect Dis Clin North Am. 2000 Sep; 14(3):761-84. PMID: 10987119.
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    148. Abruzzo GK, Gill CJ, Flattery AM, Kong L, Leighton C, Smith JG, Pikounis VB, Bartizal K, Rosen H. Efficacy of the echinocandin caspofungin against disseminated aspergillosis and candidiasis in cyclophosphamide-induced immunosuppressed mice. Antimicrob Agents Chemother. 2000 Sep; 44(9):2310-8. PMID: 10952573; PMCID: PMC90063.
    149. Rosen HR, Gretch D, Kaufman E, Quan S. Humoral immune response to hepatitis C after liver transplantation: assessment of a new recombinant immunoblot assay. Am J Gastroenterol. 2000 Aug; 95(8):2035-9. PMID: 10950054.
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    150. Rosen HR. Disease recurrence following liver transplantation. Clin Liver Dis. 2000 Aug; 4(3):675-89, ix-x. PMID: 11232167.
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    151. Rosen H, Muhlestein JB, Bartlett J, Chen S, Chikami G, Corson M, Shah PK, Gurfinkel E, Handsfield H, Jackson L, Knirsch C, Kronmal R, McCutchan JA, Shea S. Collaborative multidisciplinary workshop report: clinical antimicrobial trials for primary and secondary prevention of atherosclerotic cardiovascular disease. J Infect Dis. 2000 Jun; 181 Suppl 3:S582-4. PMID: 10839764.
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    152. Kirk EA, Dinauer MC, Rosen H, Chait A, Heinecke JW, LeBoeuf RC. Impaired superoxide production due to a deficiency in phagocyte NADPH oxidase fails to inhibit atherosclerosis in mice. Arterioscler Thromb Vasc Biol. 2000 Jun; 20(6):1529-35. PMID: 10845868.
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    153. Rabkin JM, Oroloff SL, Corless CL, Benner KG, Flora KD, Rosen HR, Olyaei AJ. Association of fungal infection and increased mortality in liver transplant recipients. Am J Surg. 2000 May; 179(5):426-30. PMID: 10930495.
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    154. deMattos A, Rosen HR. To C or not to C: these are the questions in renal transplantation. Transplantation. 2000 Apr 15; 69(7):1236-7. PMID: 10798733.
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    155. Rosen HR. Primer on hepatitis C for hospital epidemiologists. Infect Control Hosp Epidemiol. 2000 Mar; 21(3):229-34. PMID: 10738998.
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    156. Gopal DV, Rosen HR. Abnormal findings on liver function tests. Interpreting results to narrow the diagnosis and establish a prognosis. Postgrad Med. 2000 Feb; 107(2):100-2, 105-9, 113-4. PMID: 10689411.
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    157. Rosen HR, Martin P. Hepatitis B and C in the liver transplant recipient. Semin Liver Dis. 2000; 20(4):465-80. PMID: 11200416.
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    158. Rosen HR, Lentz JJ, Rose SL, Rabkin J, Corless CL, Taylor K, Chou S. Donor polymorphism of tumor necrosis factor gene: relationship with variable severity of hepatitis C recurrence after liver transplantation. Transplantation. 1999 Dec 27; 68(12):1898-902. PMID: 10628771.
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    159. Sauaia A, Alexander W, Moore EE, Stevens BR, Rosen H, Dunn TR. Autologous blood transfusion does not reduce postoperative infection rates in elective surgery. Am J Surg. 1999 Dec; 178(6):549-55. PMID: 10670870.
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    160. Zaman A, Hapke R, Flora K, Rosen HR, Benner K. Factors predicting the presence of esophageal or gastric varices in patients with advanced liver disease. Am J Gastroenterol. 1999 Nov; 94(11):3292-6. PMID: 10566732.
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    161. Rosen HR, Chou S, Sasaki AW, Gretch DR. Molecular epidemiology of hepatitis C infection in U.S. veteran liver transplant recipients: evidence for decreasing relative prevalence of genotype 1B. Am J Gastroenterol. 1999 Oct; 94(10):3015-9. PMID: 10520862.
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    162. Rosen HR, Hinrichs DJ, Gretch DR, Koziel MJ, Chou S, Houghton M, Rabkin J, Corless CL, Bouwer HG. Association of multispecific CD4(+) response to hepatitis C and severity of recurrence after liver transplantation. Gastroenterology. 1999 Oct; 117(4):926-32. PMID: 10500076.
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    163. Rosen HR, Gretch DR. Hepatitis C virus: current understanding and prospects for future therapies. Mol Med Today. 1999 Sep; 5(9):393-9. PMID: 10462751.
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    164. Ghobrial RM, Farmer DG, Baquerizo A, Colquhoun S, Rosen HR, Yersiz H, Markmann JF, Drazan KE, Holt C, Imagawa D, Goldstein LI, Martin P, Busuttil RW. Orthotopic liver transplantation for hepatitis C: outcome, effect of immunosuppression, and causes of retransplantation during an 8-year single-center experience. Ann Surg. 1999 Jun; 229(6):824-31; discussion 831-3. PMID: 10363896; PMCID: PMC1420829.
    165. Kohler J, Dorso KL, Young K, Hammond GG, Rosen H, Kropp H, Silver LL. In vitro activities of the potent, broad-spectrum carbapenem MK-0826 (L-749,345) against broad-spectrum beta-lactamase-and extended-spectrum beta-lactamase-producing Klebsiella pneumoniae and Escherichia coli clinical isolates. Antimicrob Agents Chemother. 1999 May; 43(5):1170-6. PMID: 10223931; PMCID: PMC89128.
    166. Barkhuizen A, Rosen HR, Wolf S, Flora K, Benner K, Bennett RM. Musculoskeletal pain and fatigue are associated with chronic hepatitis C: a report of 239 hepatology clinic patients. Am J Gastroenterol. 1999 May; 94(5):1355-60. PMID: 10235218.
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    167. Orloff SL, Busch AM, Olyaei AJ, Corless CL, Benner KG, Flora KD, Rosen HR, Rabkin JM. Vancomycin-resistant Enterococcus in liver transplant patients. Am J Surg. 1999 May; 177(5):418-22. PMID: 10365883.
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    168. Zaman A, Hapke R, Flora K, Rosen H, Benner K. Prevalence of upper and lower gastrointestinal tract findings in liver transplant candidates undergoing screening endoscopic evaluation. Am J Gastroenterol. 1999 Apr; 94(4):895-9. PMID: 10201453.
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    169. Madoff RD, Rosen HR, Baeten CG, LaFontaine LJ, Cavina E, Devesa M, Rouanet P, Christiansen J, Faucheron JL, Isbister W, Köhler L, Guelinckx PJ, Påhlman L. Safety and efficacy of dynamic muscle plasty for anal incontinence: lessons from a prospective, multicenter trial. Gastroenterology. 1999 Mar; 116(3):549-56. PMID: 10029613.
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    170. Rosen HR, Madden JP, Martin P. A model to predict survival following liver retransplantation. Hepatology. 1999 Feb; 29(2):365-70. PMID: 9918911.
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    171. Schiodt FV, Atillasoy E, Shakil AO, Schiff ER, Caldwell C, Kowdley KV, Stribling R, Crippin JS, Flamm S, Somberg KA, Rosen H, McCashland TM, Hay JE, Lee WM. Etiology and outcome for 295 patients with acute liver failure in the United States. Liver Transpl Surg. 1999 Jan; 5(1):29-34. PMID: 9873089.
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    172. Rosen HR, Corless CL, Rabkin J, Chou S. Association of cytomegalovirus genotype with graft rejection after liver transplantation. Transplantation. 1998 Dec 27; 66(12):1627-31. PMID: 9884250.
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    173. Rosen HR, Martin P. Hepatitis C infection in patients undergoing liver retransplantation. Transplantation. 1998 Dec 27; 66(12):1612-6. PMID: 9884247.
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    174. Gill CJ, Jackson JJ, Gerckens LS, Pelak BA, Thompson RK, Sundelof JG, Kropp H, Rosen H. In vivo activity and pharmacokinetic evaluation of a novel long-acting carbapenem antibiotic, MK-826 (L-749,345). Antimicrob Agents Chemother. 1998 Aug; 42(8):1996-2001. PMID: 9687396; PMCID: PMC105722.
    175. Rosen H, Michel BR, vanDevanter DR, Hughes JP. Differential effects of myeloperoxidase-derived oxidants on Escherichia coli DNA replication. Infect Immun. 1998 Jun; 66(6):2655-9. PMID: 9596730; PMCID: PMC108252.
    176. Ghobrial RM, Colquhoun S, Rosen H, Hollis P, Ponthieux S, Pakrasi A, Farmer DG, Markman JF, Markowitz J, Drazan K, Yersiz H, Singer J, Stribling R, Arnout W, Holt CD, Goss J, Imagawa D, Seu P, Goldstein LI, Shackleton CR, Martin P, Busuttil RW. Retransplantation for recurrent hepatitis C following tacrolimus or cyclosporine immunosuppression. Transplant Proc. 1998 Jun; 30(4):1470-1. PMID: 9636597.
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    177. Rosen HR, Gretch DR, Oehlke M, Flora KD, Benner KG, Rabkin JM, Corless CL. Timing and severity of initial hepatitis C recurrence as predictors of long-term liver allograft injury. Transplantation. 1998 May 15; 65(9):1178-82. PMID: 9603164.
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    178. Rabkin JM, Corless CL, Orloff SL, Benner KG, Flora KD, Rosen HR, Olyaei AJ. Liver transplantation for disulfiram-induced hepatic failure. Am J Gastroenterol. 1998 May; 93(5):830-1. PMID: 9625138.
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    179. Rabkin JM, Orloff SL, Corless CL, Benner KG, Flora KD, Rosen HR, Keller FS, Barton RE, Lakin PC, Petersen BD, Saxon RR, Olyaei AJ. Hepatic allograft abscess with hepatic arterial thrombosis. Am J Surg. 1998 May; 175(5):354-9. PMID: 9600276.
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    180. Rosen HR, Novi G, Zoech G, Feil W, Urbarz C, Schiessel R. Restoration of anal sphincter function by single-stage dynamic graciloplasty with a modified (split sling) technique. Am J Surg. 1998 Mar; 175(3):187-93. PMID: 9560117.
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    181. Flora K, Hahn M, Rosen H, Benner K. Milk thistle (Silybum marianum) for the therapy of liver disease. Am J Gastroenterol. 1998 Feb; 93(2):139-43. PMID: 9468229.
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    182. Rosen HR. Liver disease associated with alpha1-antitrypsin deficiency. Clin Liver Dis. 1998 Feb; 2(1):175-85. PMID: 15560052.
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    183. Rabkin JM, Orloff SL, Reed MH, Wheeler LJ, Corless CL, Benner KG, Flora KD, Rosen HR, Olyaei AJ. Biliary tract complications of side-to-side without T tube versus end-to-end with or without T tube choledochocholedochostomy in liver transplant recipients. Transplantation. 1998 Jan 27; 65(2):193-9. PMID: 9458013.
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    184. Rosen HR, Martin P, Goss J, Donovan J, Melinek J, Rudich S, Imagawa DK, Kinkhabwala M, Seu P, Busuttil RW, Shackleton CR. Significance of early aminotransferase elevation after liver transplantation. Transplantation. 1998 Jan 15; 65(1):68-72. PMID: 9448146.
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    185. Abruzzo GK, Flattery AM, Gill CJ, Kong L, Smith JG, Pikounis VB, Balkovec JM, Bouffard AF, Dropinski JF, Rosen H, Kropp H, Bartizal K. Evaluation of the echinocandin antifungal MK-0991 (L-743,872): efficacies in mouse models of disseminated aspergillosis, candidiasis, and cryptococcosis. Antimicrob Agents Chemother. 1997 Nov; 41(11):2333-8. PMID: 9371329; PMCID: PMC164124.
    186. Rosen H, Michel BR. Redundant contribution of myeloperoxidase-dependent systems to neutrophil-mediated killing of Escherichia coli. Infect Immun. 1997 Oct; 65(10):4173-8. PMID: 9317024; PMCID: PMC175600.
    187. Rosen HR, Chou S, Corless CL, Gretch DR, Flora KD, Boudousquie A, Orloff SL, Rabkin JM, Benner KG. Cytomegalovirus viremia: risk factor for allograft cirrhosis after liver transplantation for hepatitis C. Transplantation. 1997 Sep 15; 64(5):721-6. PMID: 9311709.
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    188. Beck LA, Dalke S, Leiferman KM, Bickel CA, Hamilton R, Rosen H, Bochner BS, Schleimer RP. Cutaneous injection of RANTES causes eosinophil recruitment: comparison of nonallergic and allergic human subjects. J Immunol. 1997 Sep 15; 159(6):2962-72. PMID: 9300720.
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    189. Rosen HR, Shackleton CR, Higa L, Gralnek IM, Farmer DA, McDiarmid SV, Holt C, Lewin KJ, Busuttil RW, Martin P. Use of OKT3 is associated with early and severe recurrence of hepatitis C after liver transplantation. Am J Gastroenterol. 1997 Sep; 92(9):1453-7. PMID: 9317061.
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    190. Sundelof JG, Hajdu R, Gill CJ, Thompson R, Rosen H, Kropp H. Pharmacokinetics of L-749,345, a long-acting carbapenem antibiotic, in primates. Antimicrob Agents Chemother. 1997 Aug; 41(8):1743-8. PMID: 9257753; PMCID: PMC163997.
    191. Lee JW, Beckham C, Michel BR, Rosen H, Deeg HJ. HLA-DR-mediated signals for hematopoiesis and induction of apoptosis involve but are not limited to a nitric oxide pathway. Blood. 1997 Jul 01; 90(1):217-25. PMID: 9207456.
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    192. Rosen HR, Winkle PJ, Kendall BJ, Diehl DL. Biliary interleukin-6 and tumor necrosis factor-alpha in patients undergoing endoscopic retrograde cholangiopancreatography. Dig Dis Sci. 1997 Jun; 42(6):1290-4. PMID: 9201097.
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    193. Rosen HR. Acquisition of hepatitis C by a conjunctival splash. Am J Infect Control. 1997 Jun; 25(3):242-7. PMID: 9202821.
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    194. Hellman R, Regan J, Rosen H. Effect of intensive treatment of diabetes of the risk of death or renal failure in NIDDM and IDDM. Diabetes Care. 1997 Mar; 20(3):258-64. PMID: 9051368.
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    195. Rosen HR, Benner KG, Flora KD, Rabkin JM, Orloff SL, Olyaei A, Chou S. Development of ganciclovir resistance during treatment of primary cytomegalovirus infection after liver transplantation. Transplantation. 1997 Feb 15; 63(3):476-8. PMID: 9039944.
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    196. O'Reilly PM, Rosen HR, Shackleton CR, McDiarmid S, Holt C, Busuttil RW, Martin P. Causes of graft loss following liver transplantation for chronic hepatitis C. Transplant Proc. 1997 Feb-Mar; 29(1-2):526-8. PMID: 9123116.
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    197. Rosen HR, Martin P. OKT3 and hepatitis C: defining the risks. Transplantation. 1997 Jan 15; 63(1):171-2. PMID: 9000685.
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    198. Rosen HR, O'Reilly PM, Shackleton CR, McDiarmid S, Holt C, Busuttil RW, Martin P. Graft loss following liver transplantation in patients with chronic hepatitis C. Transplantation. 1996 Dec 27; 62(12):1773-6. PMID: 8990361.
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    199. Flora KD, Rosen HR, Benner KG. The use of naturopathic remedies for chronic liver disease. Am J Gastroenterol. 1996 Dec; 91(12):2654-5. PMID: 8947022.
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    200. Rosen HR, Shackleton CR, Martin P. Indications for and timing of liver transplantation. Med Clin North Am. 1996 Sep; 80(5):1069-102. PMID: 8804375.
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    201. Ovadia H, Magenheim Y, Behar O, Rosen H. Molecular characterization of immune derived proenkephalin mRNA and the involvement of the adrenergic system in its expression in rat lymphoid cells. J Neuroimmunol. 1996 Aug; 68(1-2):77-83. PMID: 8784263.
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    202. Rosen HR, Martin P, Schiller GJ, Territo M, Lewin DN, Shackleton CR, Busuttil RW. Orthotopic liver transplantation for bone-marrow transplant-associated veno-occlusive disease and graft-versus-host disease of the liver. Liver Transpl Surg. 1996 May; 2(3):225-32. PMID: 9346652.
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    203. Gordon EJ, Myers KJ, Dougherty JP, Rosen H, Ron Y. Both anti-CD11a (LFA-1) and anti-CD11b (MAC-1) therapy delay the onset and diminish the severity of experimental autoimmune encephalomyelitis. J Neuroimmunol. 1995 Nov; 62(2):153-60. PMID: 7499503.
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    204. Sedlak J, Reinerova M, Hunakova L, Ausch C, Chorvath B, Rosen H, Moroz C. Alterations of cell surface antigens induced by placental isoform of ferritin in human carcinoma cell lines. Cancer Lett. 1995 Jul 20; 94(1):101-6. PMID: 7542560.
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    205. Jupiter JB, Ring D, Rosen H. The complications and difficulties of management of nonunion in the severely obese. J Orthop Trauma. 1995; 9(5):363-70. PMID: 8537837.
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    206. Demetriou AA, Rozga J, Podesta L, Lepage E, Morsiani E, Moscioni AD, Hoffman A, McGrath M, Kong L, Rosen H, et al. Early clinical experience with a hybrid bioartificial liver. Scand J Gastroenterol Suppl. 1995; 208:111-7. PMID: 7777790.
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    207. Stierer M, Rosen H, Weber R, Hanak H, Auerbach L, Spona J, Tüchler H. A prospective analysis of immunohistochemically determined hormone receptors and nuclear features as predictors of early recurrence in primary breast cancer. Breast Cancer Res Treat. 1995; 36(1):11-21. PMID: 7579502.
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    208. Rosen AC, Rosen HR, Huber K, Bauer K, Ausch C, Redlich K, Klein MJ, Moroz C. Correlation of placental isoferritin with birth weight and time point of first contractions. Gynecol Obstet Invest. 1995; 39(1):11-4. PMID: 7890246.
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    209. Rosen H. Primary biliary cirrhosis and bone disease. Hepatology. 1995 Jan; 21(1):253-5. PMID: 7806161.
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    210. Stamm C, Burkhalter CE, Pearce W, Larsen B, Willis M, Kikendall JW, Moses F, Rosen H, Wong RK. Benign colonic ulcers associated with nonsteroidal antiinflammatory drug ingestion. Am J Gastroenterol. 1994 Dec; 89(12):2230-3. PMID: 7977247.
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    211. Konteatis ZD, Siciliano SJ, Van Riper G, Molineaux CJ, Pandya S, Fischer P, Rosen H, Mumford RA, Springer MS. Development of C5a receptor antagonists. Differential loss of functional responses. J Immunol. 1994 Nov 01; 153(9):4200-5. PMID: 7930622.
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    212. Hoffman AL, Rosen HR, Ljubimova JU, Sher L, Podesta LG, Demetriou AA, Makowka L. Hepatic regeneration: current concepts and clinical implications. Semin Liver Dis. 1994 May; 14(2):190-210. PMID: 8047902.
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    213. Van Riper G, Nicholson DW, Scheid MP, Fischer PA, Springer MS, Rosen H. Induction, characterization, and functional coupling of the high affinity chemokine receptor for RANTES and macrophage inflammatory protein-1 alpha upon differentiation of an eosinophilic HL-60 cell line. J Immunol. 1994 Apr 15; 152(8):4055-61. PMID: 7511665.
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    214. Rosen AC, Sevelda P, Klein M, Graf AH, Lahousen M, Reiner A, Auerbach L, Vavra N, Rosen HR. A comparative analysis of management and prognosis in stage I and II fallopian tube carcinoma and epithelial ovarian cancer. Br J Cancer. 1994 Mar; 69(3):577-9. PMID: 8123490; PMCID: PMC1968857.
    215. Rakita RM, Michel BR, Rosen H. Inactivation of Escherichia coli penicillin-binding proteins by human neutrophils. Infect Immun. 1994 Jan; 62(1):162-5. PMID: 8262623; PMCID: PMC186081.
    216. Koo GC, Rosen H, Sirotina A, Ma XD, Shultz LD. Anti-CD11b antibody prevents immunopathologic changes in viable moth-eaten bone marrow chimeric mice. J Immunol. 1993 Dec 15; 151(12):6733-41. PMID: 8258688.
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    217. Meurer R, Van Riper G, Feeney W, Cunningham P, Hora D, Springer MS, MacIntyre DE, Rosen H. Formation of eosinophilic and monocytic intradermal inflammatory sites in the dog by injection of human RANTES but not human monocyte chemoattractant protein 1, human macrophage inflammatory protein 1 alpha, or human interleukin 8. J Exp Med. 1993 Dec 01; 178(6):1913-21. PMID: 7504053; PMCID: PMC2191290.
    218. Cervia JS, Rosen H, Murray HW. Effector role of blood monocytes in experimental visceral leishmaniasis. Infect Immun. 1993 Apr; 61(4):1330-3. PMID: 8454335; PMCID: PMC281366.
    219. Whitcup SM, DeBarge LR, Rosen H, Nussenblatt RB, Chan CC. Monoclonal antibody against CD11b/CD18 inhibits endotoxin-induced uveitis. Invest Ophthalmol Vis Sci. 1993 Mar; 34(3):673-81. PMID: 8095493.
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    220. Van Riper G, Siciliano S, Fischer PA, Meurer R, Springer MS, Rosen H. Characterization and species distribution of high affinity GTP-coupled receptors for human rantes and monocyte chemoattractant protein 1. J Exp Med. 1993 Mar 01; 177(3):851-6. PMID: 7679712; PMCID: PMC2190951.
    221. Rosen HR, Stierer M, Göttlicher J, Wolf H, Spoula H, Eibl M. Determination of placental ferritin-positive peripheral lymphocytes in early stages of breast cancer. Am J Surg. 1993 Feb; 165(2):213-7. PMID: 8427398.
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    222. Borsook D, Rosen H, Collard M, Dressler H, Herrup K, Comb MJ, Hyman SE. Expression and regulation of a proenkephalin beta-galactosidase fusion gene in the reproductive system of transgenic mice. Mol Endocrinol. 1992 Sep; 6(9):1502-12. PMID: 1435791.
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    223. Mielke ME, Rosen H, Brocke S, Peters C, Hahn H. Protective immunity and granuloma formation are mediated by two distinct tumor necrosis factor alpha- and gamma interferon-dependent T cell-phagocyte interactions in murine listeriosis: dissociation on the basis of phagocyte adhesion mechanisms. Infect Immun. 1992 May; 60(5):1875-82. PMID: 1563777; PMCID: PMC257088.
    224. Rosen HR, Vlahakes GJ, Rattner DW. Fulminant peptic ulcer disease in cardiac surgical patients: pathogenesis, prevention, and management. Crit Care Med. 1992 Mar; 20(3):354-9. PMID: 1347261.
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    225. Rosen HR, Marczell AP, Czerwenka E, Stierer MO, Spoula H, Wasl H. Local gentamicin application for perineal wound healing following abdominoperineal rectum excision. Am J Surg. 1991 Nov; 162(5):438-41. PMID: 1951905.
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    226. Rakita RM, Rosen H. Penicillin-binding protein inactivation by human neutrophil myeloperoxidase. J Clin Invest. 1991 Sep; 88(3):750-4. PMID: 1653273; PMCID: PMC295453.
    227. Blankenstein T, Qin ZH, Uberla K, Müller W, Rosen H, Volk HD, Diamantstein T. Tumor suppression after tumor cell-targeted tumor necrosis factor alpha gene transfer. J Exp Med. 1991 May 01; 173(5):1047-52. PMID: 2022919; PMCID: PMC2118861.
    228. Rosen H. 1,25(OH)2 vitamin D for osteoporosis. Ann Intern Med. 1991 Mar 15; 114(6):519-20. PMID: 1994801.
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    229. Heyworth PG, Curnutte JT, Nauseef WM, Volpp BD, Pearson DW, Rosen H, Clark RA. Neutrophil nicotinamide adenine dinucleotide phosphate oxidase assembly. Translocation of p47-phox and p67-phox requires interaction between p47-phox and cytochrome b558. J Clin Invest. 1991 Jan; 87(1):352-6. PMID: 1985107; PMCID: PMC295061.
    230. Rosen H. Role of CR3 in induced myelomonocytic recruitment: insights from in vivo monoclonal antibody studies in the mouse. J Leukoc Biol. 1990 Nov; 48(5):465-9. PMID: 2230596.
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    231. Dinauer MC, Curnutte JT, Rosen H, Orkin SH. A missense mutation in the neutrophil cytochrome b heavy chain in cytochrome-positive X-linked chronic granulomatous disease. J Clin Invest. 1989 Dec; 84(6):2012-6. PMID: 2556453; PMCID: PMC304086.
    232. Rosen H, Behar O, Abramsky O, Ovadia H. Regulated expression of proenkephalin A in normal lymphocytes. J Immunol. 1989 Dec 01; 143(11):3703-7. PMID: 2584715.
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    233. Rosen H, Gordon S, North RJ. Exacerbation of murine listeriosis by a monoclonal antibody specific for the type 3 complement receptor of myelomonocytic cells. Absence of monocytes at infective foci allows Listeria to multiply in nonphagocytic cells. J Exp Med. 1989 Jul 01; 170(1):27-37. PMID: 2501445; PMCID: PMC2189368.
    234. Stierer M, Rosen HR. [Effect of early diagnosis on the prognosis of metastatic breast cancer]. Wien Klin Wochenschr. 1989 Feb 17; 101(4):138-42. PMID: 2929158.
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    235. Rosen H, Milon G, Gordon S. Antibody to the murine type 3 complement receptor inhibits T lymphocyte-dependent recruitment of myelomonocytic cells in vivo. J Exp Med. 1989 Feb 01; 169(2):535-48. PMID: 2521356; PMCID: PMC2189217.
    236. Kennedy CA, Rosen H. Kingella kingae bacteremia and adult epiglottitis in a granulocytopenic host. Am J Med. 1988 Nov; 85(5):701-2. PMID: 3189372.
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    237. Rosen H, Gordon S. Monoclonal antibody to the murine type 3 complement receptor inhibits adhesion of myelomonocytic cells in vitro and inflammatory cell recruitment in vivo. J Exp Med. 1987 Dec 01; 166(6):1685-701. PMID: 2445894; PMCID: PMC2188801.
    238. Heinecke JW, Baker L, Rosen H, Chait A. Superoxide-mediated modification of low density lipoprotein by arterial smooth muscle cells. J Clin Invest. 1986 Mar; 77(3):757-61. PMID: 3005364; PMCID: PMC423460.
    239. Comb M, Liston D, Martin M, Rosen H, Herbert E. Expression of the human proenkephalin gene in mouse pituitary cells: accurate and efficient mRNA production and proteolytic processing. EMBO J. 1985 Dec 01; 4(12):3115-22. PMID: 3004933; PMCID: PMC554630.
    240. Rosen H, Klebanoff SJ. Oxidation of microbial iron-sulfur centers by the myeloperoxidase-H2O2-halide antimicrobial system. Infect Immun. 1985 Mar; 47(3):613-8. PMID: 2982737; PMCID: PMC261335.
    241. Heinecke JW, Rosen H, Chait A. Iron and copper promote modification of low density lipoprotein by human arterial smooth muscle cells in culture. J Clin Invest. 1984 Nov; 74(5):1890-4. PMID: 6501577; PMCID: PMC425370.
    242. Rosen H, Knoller S, Kaempfer R. Messenger ribonucleic acid specificity in the inhibition of eukaryotic translation by double-stranded ribonucleic acid. Biochemistry. 1981 May 26; 20(11):3011-20. PMID: 6264950.
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    243. Rosen H, Klebanoff SJ. Hydroxyl radical generation by polymorphonuclear leukocytes measured by electron spin resonance spectroscopy. J Clin Invest. 1979 Dec; 64(6):1725-9. PMID: 227939; PMCID: PMC371329.
    244. Rosen H, Klebanoff SJ. Bactericidal activity of a superoxide anion-generating system. A model for the polymorphonuclear leukocyte. J Exp Med. 1979 Jan 01; 149(1):27-39. PMID: 216766; PMCID: PMC2184741.
    245. Klebanoff SJ, Rosen H. Ethylene formation by polymorphonuclear leukocytes. Role of myeloperoxidase. J Exp Med. 1978 Aug 01; 148(2):490-506. PMID: 212502; PMCID: PMC2184952.
    246. Klebanoff SJ, Durack DT, Rosen H, Clark RA. Functional studies on human peritoneal eosinophils. Infect Immun. 1977 Jul; 17(1):167-73. PMID: 195901; PMCID: PMC421098.
    247. Rosen H, Klebanoff SJ. Chemiluminescence and superoxide production by myeloperoxidase-deficient leukocytes. J Clin Invest. 1976 Jul; 58(1):50-60. PMID: 180060; PMCID: PMC333154.
    248. Friedman SA, Rosen H. Uremia and cardiovascular mortality. Ann Intern Med. 1974 Nov; 81(5):696-7. PMID: 4420935.
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    249. Lee S, Edgington TS, Smallwood CJ, Thompson AG, Chandler JG, Rosen H, Orloff MJ. Secretory function and relative resistance of the gastric mucosa of the rat to allogeneic rejection. Transplantation. 1972 Nov; 14(5):641-8. PMID: 4563202.
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    250. Friedman SA, Raizner AE, Rosen H, Solomon NA, Sy W. Functional defects in the aging kidney. Ann Intern Med. 1972 Jan; 76(1):41-5. PMID: 5021553.
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    251. Villar H, Abbott AG, Williams RJ, Rosen H, Orloff MJ. Nature of the gastric hypersecretion associated with intestinal exclusion. Surg Forum. 1971; 22:299-300. PMID: 5121380.
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    252. Orloff MJ, Abbott AG, Rosen H. Nature of the humoral agent responsible for portacaval shunt-related gastric hypersecretion in man. Am J Surg. 1970 Aug; 120(2):237-43. PMID: 5456411.
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    253. Orloff MJ, Villar-Valdes H, Abbott AG, Williams RJ, Rosen H. Site of origin of the hormone responsible for gastric hypersecretion associated with portacaval shunt. Surgery. 1970 Jul; 68(1):202-7; discussion 207-8. PMID: 10483470.
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    254. Lee S, Keiter JE, Rosen H, Williams R, Chandler JG, Orloff MJ. Influence of blood supply on regeneration of liver transplants. Surg Forum. 1969; 20:369-71. PMID: 4910611.
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    255. Carter D, Einheber A, Bauer H, Rosen H, Burns WF. The role of the microbial flora in uremia. II. Uremic colitis, cardiovascular lesions, and biochemical observations. J Exp Med. 1966 Feb 01; 123(2):251-66. PMID: 5905241; PMCID: PMC2138133.
    256. BEISEL WR, AUSTEN KF, ROSEN H, HERNDON EG. Metabolic observations in adult hypophosphatasia. Am J Med. 1960 Aug; 29:369-76. PMID: 13798349.
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    257. UZMAN LL, ROSEN H, FOLEY GE. Studies on the biology of Cryptococcus. VI. Amino acid composition of the somatic proteins of Cryptococcus neoformans. J Infect Dis. 1956 Mar-Apr; 98(2):208-10. PMID: 13319780.
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    258. LEVENSON SM, ADAMS MA, ROSEN H, TAYLOR FH. Studies in phosphorus metabolism in man, III. The distribution, exchange and excretion of phosphorus in man using radioactive phosphorus (P32) as a tracer. J Clin Invest. 1953 Jun; 32(6):497-509. PMID: 13052714; PMCID: PMC438372.
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