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This is a "connection" page, showing publications co-authored by Arthur Zaug and Thomas Cech.

Connection Strength
  1. Zaug AJ, Lim CJ, Olson CL, Carilli MT, Goodrich KJ, Wuttke DS, Cech TR. CST does not evict elongating telomerase but prevents initiation by ssDNA binding. Nucleic Acids Res. 2021 11 18; 49(20):11653-11665.
    View in: PubMed
    Score: 0.959
  2. Zaug AJ, Crary SM, Jesse Fioravanti M, Campbell K, Cech TR. Many disease-associated variants of hTERT retain high telomerase enzymatic activity. Nucleic Acids Res. 2013 Oct; 41(19):8969-78.
    View in: PubMed
    Score: 0.540
  3. Zaug AJ, Podell ER, Nandakumar J, Cech TR. Functional interaction between telomere protein TPP1 and telomerase. Genes Dev. 2010 Mar 15; 24(6):613-22.
    View in: PubMed
    Score: 0.427
  4. Zaug AJ, Podell ER, Cech TR. Mutation in TERT separates processivity from anchor-site function. Nat Struct Mol Biol. 2008 Aug; 15(8):870-2.
    View in: PubMed
    Score: 0.381
  5. Zaug AJ, Podell ER, Cech TR. Human POT1 disrupts telomeric G-quadruplexes allowing telomerase extension in vitro. Proc Natl Acad Sci U S A. 2005 Aug 02; 102(31):10864-9.
    View in: PubMed
    Score: 0.310
  6. Lim CJ, Barbour AT, Zaug AJ, Goodrich KJ, McKay AE, Wuttke DS, Cech TR. The structure of human CST reveals a decameric assembly bound to telomeric DNA. Science. 2020 06 05; 368(6495):1081-1085.
    View in: PubMed
    Score: 0.217
  7. Schmidt JC, Zaug AJ, Kufer R, Cech TR. Dynamics of human telomerase recruitment depend on template-telomere base pairing. Mol Biol Cell. 2018 Apr 01; 29(7):869-880.
    View in: PubMed
    Score: 0.186
  8. Lim CJ, Zaug AJ, Kim HJ, Cech TR. Reconstitution of human shelterin complexes reveals unexpected stoichiometry and dual pathways to enhance telomerase processivity. Nat Commun. 2017 10 20; 8(1):1075.
    View in: PubMed
    Score: 0.181
  9. Schmidt JC, Zaug AJ, Cech TR. Live Cell Imaging Reveals the Dynamics of Telomerase Recruitment to Telomeres. Cell. 2016 Aug 25; 166(5):1188-1197.e9.
    View in: PubMed
    Score: 0.166
  10. Xi L, Schmidt JC, Zaug AJ, Ascarrunz DR, Cech TR. A novel two-step genome editing strategy with CRISPR-Cas9 provides new insights into telomerase action and TERT gene expression. Genome Biol. 2015 Nov 10; 16:231.
    View in: PubMed
    Score: 0.158
  11. Borah S, Xi L, Zaug AJ, Powell NM, Dancik GM, Cohen SB, Costello JC, Theodorescu D, Cech TR. Cancer. TERT promoter mutations and telomerase reactivation in urothelial cancer. Science. 2015 Feb 27; 347(6225):1006-10.
    View in: PubMed
    Score: 0.150
  12. Nandakumar J, Bell CF, Weidenfeld I, Zaug AJ, Leinwand LA, Cech TR. The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity. Nature. 2012 Dec 13; 492(7428):285-9.
    View in: PubMed
    Score: 0.128
  13. Lei M, Zaug AJ, Podell ER, Cech TR. Switching human telomerase on and off with hPOT1 protein in vitro. J Biol Chem. 2005 May 27; 280(21):20449-56.
    View in: PubMed
    Score: 0.076
  14. Seto AG, Umansky K, Tzfati Y, Zaug AJ, Blackburn EH, Cech TR. A template-proximal RNA paired element contributes to Saccharomyces cerevisiae telomerase activity. RNA. 2003 Nov; 9(11):1323-32.
    View in: PubMed
    Score: 0.069
  15. Livengood AJ, Zaug AJ, Cech TR. Essential regions of Saccharomyces cerevisiae telomerase RNA: separate elements for Est1p and Est2p interaction. Mol Cell Biol. 2002 Apr; 22(7):2366-74.
    View in: PubMed
    Score: 0.062
  16. Tang M, Li Y, Zhang Y, Chen Y, Huang W, Wang D, Zaug AJ, Liu D, Zhao Y, Cech TR, Ma W, Songyang Z. Disease mutant analysis identifies a new function of DAXX in telomerase regulation and telomere maintenance. J Cell Sci. 2015 Jan 15; 128(2):331-41.
    View in: PubMed
    Score: 0.037
  17. Batista LF, Pech MF, Zhong FL, Nguyen HN, Xie KT, Zaug AJ, Crary SM, Choi J, Sebastiano V, Cherry A, Giri N, Wernig M, Alter BP, Cech TR, Savage SA, Reijo Pera RA, Artandi SE. Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells. Nature. 2011 May 22; 474(7351):399-402.
    View in: PubMed
    Score: 0.029
  18. Wang F, Podell ER, Zaug AJ, Yang Y, Baciu P, Cech TR, Lei M. The POT1-TPP1 telomere complex is a telomerase processivity factor. Nature. 2007 Feb 01; 445(7127):506-10.
    View in: PubMed
    Score: 0.021
  19. Förstemann K, Zaug AJ, Cech TR, Lingner J. Yeast telomerase is specialized for C/A-rich RNA templates. Nucleic Acids Res. 2003 Mar 15; 31(6):1646-55.
    View in: PubMed
    Score: 0.016
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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