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Kathryn L Hassell

TitleProfessor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-MED
Phone720/848-0300

    Collapse Research 
    Collapse research activities and funding
    R13HL083691     (HASSELL, KATHRYN L)Aug 4, 2006 - Jul 31, 2007
    NIH/NHLBI
    Consensus Conference Grant
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Keller S, Yang M, Treadwell MJ, Hassell KL. Sensitivity of alternative measures of functioning and wellbeing for adults with sickle cell disease: comparison of PROMIS® to ASCQ-Me?. Health Qual Life Outcomes. 2017 Jun 02; 15(1):117. PMID: 28577358.
      View in: PubMed
    2. Fu D, Bridle A, Leef M, Gagnon MM, Hassell KL, Nowak BF. Using a multi-biomarker approach to assess the effects of pollution on sand flathead (Platycephalus bassensis) from Port Phillip Bay, Victoria, Australia. Mar Pollut Bull. 2017 Jun 15; 119(1):211-219. PMID: 28392090.
      View in: PubMed
    3. Loomis Z, Eigenberger P, Redinius K, Lisk C, Karoor V, Nozik-Grayck E, Ferguson SK, Hassell K, Nuss R, Stenmark K, Buehler P, Irwin DC. Hemoglobin induced cell trauma indirectly influences endothelial TLR9 activity resulting in pulmonary vascular smooth muscle cell activation. PLoS One. 2017; 12(2):e0171219. PMID: 28152051.
      View in: PubMed
    4. Dampier C, Palermo TM, Darbari DS, Hassell K, Smith W, Zempsky W. AAPT Diagnostic Criteria for Chronic Sickle Cell Disease Pain. J Pain. 2017 May; 18(5):490-498. PMID: 28065813.
      View in: PubMed
    5. Morris L, Colombo V, Hassell K, Kellar C, Leahy P, Long SM, Myers JH, Pettigrove V. Municipal wastewater effluent licensing: A global perspective and recommendations for best practice. Sci Total Environ. 2017 Feb 15; 580:1327-1339. PMID: 28017416.
      View in: PubMed
    6. Baker JK, Long SM, Hassell KL, Pettigrove VJ, Gagnon MM. Health Status of Sand Flathead (Platycephalus bassensis), Inhabiting an Industrialised and Urbanised Embayment, Port Phillip Bay, Victoria as Measured by Biomarkers of Exposure and Effects. PLoS One. 2016; 11(10):e0164257. PMID: 27711198.
      View in: PubMed
    7. Evensen CT, Treadwell MJ, Keller S, Levine R, Hassell KL, Werner EM, Smith WR. Quality of care in sickle cell disease: Cross-sectional study and development of a measure for adults reporting on ambulatory and emergency department care. Medicine (Baltimore). 2016 Aug; 95(35):e4528. PMID: 27583862; PMCID: PMC5008546.
    8. Hassell KL. Sickle Cell Disease: A Continued Call to Action. Am J Prev Med. 2016 Jul; 51(1 Suppl 1):S1-2. PMID: 27320458.
      View in: PubMed
    9. Hinton CF, Homer CJ, Thompson AA, Williams A, Hassell KL, Feuchtbaum L, Berry SA, Comeau AM, Therrell BL, Brower A, Harris KB, Brown C, Monaco J, Ostrander RJ, Zuckerman AE, Kaye C, Dougherty D, Greene C, Green NS. A framework for assessing outcomes from newborn screening: on the road to measuring its promise. Mol Genet Metab. 2016 Aug; 118(4):221-9. PMID: 27268406; PMCID: PMC4970906 [Available on 08/01/17].
    10. Hassell K, Pettigrove V, Beresford N, Jobling S, Kumar A. No evidence of exposure to environmental estrogens in two feral fish species sampled from the Yarra River, Australia: A comparison with Northern Hemisphere studies. Ecotoxicol Environ Saf. 2016 Sep; 131:104-17. PMID: 27228034.
      View in: PubMed
    11. Gagnon MM, Baker JK, Long SM, Hassell KL, Pettigrove VJ. Contaminant (PAHs, OCs, PCBs and trace metals) concentrations are declining in axial tissue of sand flathead (Platycephalus bassensis) collected from an urbanised catchment (Port Phillip Bay, Australia). Mar Pollut Bull. 2016 Aug 15; 109(1):661-6. PMID: 27207026.
      View in: PubMed
    12. Thomas OR, Barbee NC, Hassell KL, Swearer SE. Smell no evil: Copper disrupts the alarm chemical response in a diadromous fish, Galaxias maculatus. Environ Toxicol Chem. 2016 Sep; 35(9):2209-14. PMID: 27552396.
      View in: PubMed
    13. Luchtman-Jones L, Pressel S, Hilliard L, Brown RC, Smith MG, Thompson AA, Lee MT, Rothman J, Rogers ZR, Owen W, Imran H, Thornburg C, Kwiatkowski JL, Aygun B, Nelson S, Roberts C, Gauger C, Piccone C, Kalfa T, Alvarez O, Hassell K, Davis BR, Ware RE. Effects of hydroxyurea treatment for patients with hemoglobin SC disease. Am J Hematol. 2016 Feb; 91(2):238-42. PMID: 26615793.
      View in: PubMed
    14. Walters MC, De Castro LM, Sullivan KM, Krishnamurti L, Kamani N, Bredeson C, Neuberg D, Hassell KL, Farnia S, Campbell A, Petersdorf E. Indications and Results of HLA-Identical Sibling Hematopoietic Cell Transplantation for Sickle Cell Disease. Biol Blood Marrow Transplant. 2016 Feb; 22(2):207-11. PMID: 26500093.
      View in: PubMed
    15. Morris CR, Kim HY, Klings ES, Wood J, Porter JB, Trachtenberg F, Sweeters N, Olivieri NF, Kwiatkowski JL, Virzi L, Hassell K, Taher A, Neufeld EJ, Thompson AA, Larkin S, Suh JH, Vichinsky EP, Kuypers FA. Dysregulated arginine metabolism and cardiopulmonary dysfunction in patients with thalassaemia. Br J Haematol. 2015 Jun; 169(6):887-98. PMID: 25907665; PMCID: PMC4452408.
    16. Savage WJ, Buchanan GR, Yawn BP, Afenyi-Annan AN, Ballas SK, Goldsmith JC, Hassell KL, James AH, John-Sowah J, Jordan L, Lottenberg R, Murad MH, Ortiz E, Tanabe PJ, Ware RE, Lanzkron SM. Evidence gaps in the management of sickle cell disease: A summary of needed research. Am J Hematol. 2015 Apr; 90(4):273-5. PMID: 25639238.
      View in: PubMed
    17. Irwin DC, Baek JH, Hassell K, Nuss R, Eigenberger P, Lisk C, Loomis Z, Maltzahn J, Stenmark KR, Nozik-Grayck E, Buehler PW. Hemoglobin-induced lung vascular oxidation, inflammation, and remodeling contribute to the progression of hypoxic pulmonary hypertension and is attenuated in rats with repeated-dose haptoglobin administration. Free Radic Biol Med. 2015 May; 82:50-62. PMID: 25656991; PMCID: PMC4387123.
    18. Yawn BP, Buchanan G, Hassell K. Management of patients with sickle cell disease--reply. JAMA. 2015 Jan 06; 313(1):91-2. PMID: 25562275.
      View in: PubMed
    19. Goodman J, Hassell K, Irwin D, Witkowski EH, Nuss R. The splenic syndrome in individuals with sickle cell trait. High Alt Med Biol. 2014 Dec; 15(4):468-71. PMID: 25361178; PMCID: PMC4273194.
    20. Quirolo K, Bertolone S, Hassell K, Howard T, King KE, Rhodes DK, Bill J. The evaluation of a new apheresis device for automated red blood cell exchange procedures in patients with sickle cell disease. Transfusion. 2015 Apr; 55(4):775-81. PMID: 25330984.
      View in: PubMed
    21. Anderson M, Hassell KL, Trujillo TC, Wolfe B. When patients on target-specific oral anticoagulants need surgery. Cleve Clin J Med. 2014 Oct; 81(10):629-39. PMID: 25274657.
      View in: PubMed
    22. Treadwell MJ, Hassell K, Levine R, Keller S. Adult sickle cell quality-of-life measurement information system (ASCQ-Me): conceptual model based on review of the literature and formative research. Clin J Pain. 2014 Oct; 30(10):902-14. PMID: 24300219; PMCID: PMC4993284.
    23. Yawn BP, Buchanan GR, Afenyi-Annan AN, Ballas SK, Hassell KL, James AH, Jordan L, Lanzkron SM, Lottenberg R, Savage WJ, Tanabe PJ, Ware RE, Murad MH, Goldsmith JC, Ortiz E, Fulwood R, Horton A, John-Sowah J. Management of sickle cell disease: summary of the 2014 evidence-based report by expert panel members. JAMA. 2014 Sep 10; 312(10):1033-48. PMID: 25203083.
      View in: PubMed
    24. Keller SD, Yang M, Treadwell MJ, Werner EM, Hassell KL. Patient reports of health outcome for adults living with sickle cell disease: development and testing of the ASCQ-Me item banks. Health Qual Life Outcomes. 2014 Aug 22; 12:125. PMID: 25146160; PMCID: PMC4243820.
    25. Hassell KL, Afenyi-Annan A, Ballas SK, Buchanan GR, Eckman JR, Jordan L, Lanzkron S, Lottenberg R, Ware R. Practice guideline for pulmonary hypertension in sickle cell: direct evidence needed before universal adoption. Am J Respir Crit Care Med. 2014 Jul 15; 190(2):237-8. PMID: 25025359.
      View in: PubMed
    26. Babilonia KM, Golightly LK, Gutman JA, Hassell KL, Kaiser JN, Kiser TH, Klem PM, Trujillo TC. Antithrombotic therapy in patients with thrombocytopenic cancer: outcomes associated with reduced-dose, low-molecular-weight heparin during hospitalization. Clin Appl Thromb Hemost. 2014 Nov; 20(8):799-806. PMID: 25022565.
      View in: PubMed
    27. Gladwin MT, Barst RJ, Gibbs JS, Hildesheim M, Sachdev V, Nouraie M, Hassell KL, Little JA, Schraufnagel DE, Krishnamurti L, Novelli E, Girgis RE, Morris CR, Berman Rosenzweig E, Badesch DB, Lanzkron S, Castro OL, Taylor JG, Goldsmith JC, Kato GJ, Gordeuk VR, Machado RF. Risk factors for death in 632 patients with sickle cell disease in the United States and United Kingdom. PLoS One. 2014; 9(7):e99489. PMID: 24988120; PMCID: PMC4079316.
    28. Lisk C, Kominsky D, Ehrentraut S, Bonaventura J, Nuss R, Hassell K, Nozik-Grayck E, Irwin DC. Hemoglobin-induced endothelial cell permeability is controlled, in part, via a myeloid differentiation primary response gene-88-dependent signaling mechanism. Am J Respir Cell Mol Biol. 2013 Oct; 49(4):619-26. PMID: 23713977.
      View in: PubMed
    29. Shanthanagouda AH, Nugegoda D, Hassell KL, Patil JG. Exposure to estrogenic chemicals induces ectopic expression of vtg in the testis of rainbowfish, Melanotaenia fluviatilis. Bull Environ Contam Toxicol. 2013 Oct; 91(4):438-43. PMID: 23934007.
      View in: PubMed
    30. Delaney KM, Axelrod KC, Buscetta A, Hassell KL, Adams-Graves PE, Seamon C, Kato GJ, Minniti CP. Leg ulcers in sickle cell disease: current patterns and practices. Hemoglobin. 2013; 37(4):325-32. PMID: 23600469; PMCID: PMC3864012.
    31. Kirwan GM, Hancock T, Hassell K, Niere JO, Nugegoda D, Goto S, Adams MJ. Nuclear magnetic resonance metabonomic profiling using tO2PLS. Anal Chim Acta. 2013 Jun 05; 781:33-40. PMID: 23684462.
      View in: PubMed
    32. Ferguson EM, Allinson M, Allinson G, Swearer SE, Hassell KL. Fluctuations in natural and synthetic estrogen concentrations in a tidal estuary in south-eastern Australia. Water Res. 2013 Mar 15; 47(4):1604-15. PMID: 23305682.
      View in: PubMed
    33. Nouraie M, Lee JS, Zhang Y, Kanias T, Zhao X, Xiong Z, Oriss TB, Zeng Q, Kato GJ, Gibbs JS, Hildesheim ME, Sachdev V, Barst RJ, Machado RF, Hassell KL, Little JA, Schraufnagel DE, Krishnamurti L, Novelli E, Girgis RE, Morris CR, Rosenzweig EB, Badesch DB, Lanzkron S, Castro OL, Goldsmith JC, Gordeuk VR, Gladwin MT. The relationship between the severity of hemolysis, clinical manifestations and risk of death in 415 patients with sickle cell anemia in the US and Europe. Haematologica. 2013 Mar; 98(3):464-72. PMID: 22983573; PMCID: PMC3659937.
    34. Sachdev V, Kato GJ, Gibbs JS, Barst RJ, Machado RF, Nouraie M, Hassell KL, Little JA, Schraufnagel DE, Krishnamurti L, Novelli EM, Girgis RE, Morris CR, Rosenzweig EB, Badesch DB, Lanzkron S, Castro OL, Taylor JG, Hannoush H, Goldsmith JC, Gladwin MT, Gordeuk VR. Echocardiographic markers of elevated pulmonary pressure and left ventricular diastolic dysfunction are associated with exercise intolerance in adults and adolescents with homozygous sickle cell anemia in the United States and United Kingdom. Circulation. 2011 Sep 27; 124(13):1452-60. PMID: 21900080; PMCID: PMC3183314.
    35. Vichinsky E, Bernaudin F, Forni GL, Gardner R, Hassell K, Heeney MM, Inusa B, Kutlar A, Lane P, Mathias L, Porter J, Tebbi C, Wilson F, Griffel L, Deng W, Giannone V, Coates T. Long-term safety and efficacy of deferasirox (Exjade) for up to 5 years in transfusional iron-overloaded patients with sickle cell disease. Br J Haematol. 2011 Aug; 154(3):387-97. PMID: 21592110; PMCID: PMC3170481.
    36. Smith WR, Jordan LB, Hassell KL. Frequently asked questions by hospitalists managing pain in adults with sickle cell disease. J Hosp Med. 2011 May; 6(5):297-303. PMID: 21661104.
      View in: PubMed
    37. Machado RF, Barst RJ, Yovetich NA, Hassell KL, Kato GJ, Gordeuk VR, Gibbs JS, Little JA, Schraufnagel DE, Krishnamurti L, Girgis RE, Morris CR, Rosenzweig EB, Badesch DB, Lanzkron S, Onyekwere O, Castro OL, Sachdev V, Waclawiw MA, Woolson R, Goldsmith JC, Gladwin MT. Hospitalization for pain in patients with sickle cell disease treated with sildenafil for elevated TRV and low exercise capacity. Blood. 2011 Jul 28; 118(4):855-64. PMID: 21527519; PMCID: PMC3148167.
    38. Kiser TH, Mann AM, Trujillo TC, Hassell KL. Evaluation of empiric versus nomogram-based direct thrombin inhibitor management in patients with suspected heparin-induced thrombocytopenia. Am J Hematol. 2011 Mar; 86(3):267-72. PMID: 21328434.
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    39. Hassell KL. Pulmonary hypertension, tricuspid regurgitant velocity screening, and the nitric oxide pathway. Hematology Am Soc Hematol Educ Program. 2011; 2011:419-26. PMID: 22160068.
      View in: PubMed
    40. Kiser TH, MacLaren R, Fish DN, Hassell KL, Teitelbaum I. Bivalirudin versus unfractionated heparin for prevention of hemofilter occlusion during continuous renal replacement therapy. Pharmacotherapy. 2010 Nov; 30(11):1117-26. PMID: 20973685.
      View in: PubMed
    41. Tanabe P, Porter J, Creary M, Kirkwood E, Miller S, Ahmed-Williams E, Hassell K. A qualitative analysis of best self-management practices: sickle cell disease. J Natl Med Assoc. 2010 Nov; 102(11):1033-41. PMID: 21141291.
      View in: PubMed
    42. Hassell KL. Population estimates of sickle cell disease in the U.S. Am J Prev Med. 2010 Apr; 38(4 Suppl):S512-21. PMID: 20331952.
      View in: PubMed
    43. Hassell K, Pace B, Wang W, Kulkarni R, Luban N, Johnson CS, Eckman J, Lane P, Woods WG. Sickle cell disease summit: from clinical and research disparity to action. Am J Hematol. 2009 Jan; 84(1):39-45. PMID: 19021119.
      View in: PubMed
    44. Hassell K. Heparin-induced thrombocytopenia: diagnosis and management. Thromb Res. 2008; 123 Suppl 1:S16-21. PMID: 18829068.
      View in: PubMed
    45. Pratte KA, Barón AE, Ogden LG, Hassell KL, Rewers M, Hokanson JE. Plasminogen activator inhibitor-1 is associated with coronary artery calcium in Type 1 diabetes. J Diabetes Complications. 2009 Nov-Dec; 23(6):387-93. PMID: 18768333.
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    46. Kiser TH, Burch JC, Klem PM, Hassell KL. Safety, efficacy, and dosing requirements of bivalirudin in patients with heparin-induced thrombocytopenia. Pharmacotherapy. 2008 Sep; 28(9):1115-24. PMID: 18752382.
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    47. Lanzkron S, Haywood C, Hassell KL, Rand C. Provider barriers to hydroxyurea use in adults with sickle cell disease: a survey of the Sickle Cell Disease Adult Provider Network. J Natl Med Assoc. 2008 Aug; 100(8):968-73. PMID: 18717150.
      View in: PubMed
    48. Hassell KL, Coutin PC, Nugegoda D. Hypoxia impairs embryo development and survival in black bream (Acanthopagrus butcheri). Mar Pollut Bull. 2008; 57(6-12):302-6. PMID: 18420223.
      View in: PubMed
    49. Codi King S, Hassell K, Nugegoda D, Kristiansen SI. The assessment of vitellogenin as a biomarker of exposure to estrogenic compounds in two Australian perciformes. Mar Environ Res. 2008 Jul; 66(1):116-8. PMID: 18377978.
      View in: PubMed
    50. Kluger BM, Hughes RL, Anderson CA, Hassell KL. Non-traumatic carotid dissection and stroke associated with anti-phospholipid antibody syndrome: report of a case and review of the literature. Neurol India. 2008 Jan-Mar; 56(1):77-8. PMID: 18310845.
      View in: PubMed
    51. Vichinsky E, Onyekwere O, Porter J, Swerdlow P, Eckman J, Lane P, Files B, Hassell K, Kelly P, Wilson F, Bernaudin F, Forni GL, Okpala I, Ressayre-Djaffer C, Alberti D, Holland J, Marks P, Fung E, Fischer R, Mueller BU, Coates T. A randomised comparison of deferasirox versus deferoxamine for the treatment of transfusional iron overload in sickle cell disease. Br J Haematol. 2007 Feb; 136(3):501-8. PMID: 17233848; PMCID: PMC1974786.
    52. Dowling NF, Beckman MG, Manco-Johnson M, Hassell K, Philipp CS, Michaels LA, Moll S, Heit JA, Penner J, Kulkarni R, Pipe S, Bockenstedt P, Andersen J, Crudder S, James AH, Zimmerman S, Ortel TL. The U.S. Thrombosis and Hemostasis Centers pilot sites program. J Thromb Thrombolysis. 2007 Feb; 23(1):1-7. PMID: 17111206.
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    53. Hassell KL, Kefford BJ, Nugegoda D. Sub-lethal and chronic salinity tolerances of three freshwater insects: Cloeon sp. and Centroptilum sp. (Ephemeroptera: Baetidae) and Chironomus sp. (Diptera: Chironomidae). J Exp Biol. 2006 Oct; 209(Pt 20):4024-32. PMID: 17023596.
      View in: PubMed
    54. Hassell K. Pregnancy and sickle cell disease. Hematol Oncol Clin North Am. 2005 Oct; 19(5):903-16, vii-viii. PMID: 16214651.
      View in: PubMed
    55. Hassell K. The management of patients with heparin-induced thrombocytopenia who require anticoagulant therapy. Chest. 2005 Feb; 127(2 Suppl):1S-8S. PMID: 15706025.
      View in: PubMed
    56. Hassell KL. Hematologic ramifications of patent foramen ovale--role of hypercoagulable state. Cardiol Clin. 2005 Feb; 23(1):65-71. PMID: 15676269.
      View in: PubMed
    57. Lottenberg R, Hassell KL. An evidence-based approach to the treatment of adults with sickle cell disease. Hematology Am Soc Hematol Educ Program. 2005; 58-65. PMID: 16304360.
      View in: PubMed
    58. Dodge SM, Hassell K, Anderson CA, Keller J, Groves B, Carroll JD. Antiphospholipid antibodies are common in patients referred for percutaneous patent foramen ovale closure. Catheter Cardiovasc Interv. 2004 Jan; 61(1):123-7. PMID: 14696171.
      View in: PubMed
    59. Hassell KL. Altered hemostasis in pulmonary hypertension. Blood Coagul Fibrinolysis. 1998 Mar; 9(2):107-17. PMID: 9622208.
      View in: PubMed
    60. Neumayr L, Koshy M, Haberkern C, Earles AN, Bellevue R, Hassell K, Miller S, Black D, Vichinsky E. Surgery in patients with hemoglobin SC disease. Preoperative Transfusion in Sickle Cell Disease Study Group. Am J Hematol. 1998 Feb; 57(2):101-8. PMID: 9462540.
      View in: PubMed
    61. Welsh CH, Hassell KL, Badesch DB, Kressin DC, Marlar RA. Coagulation and fibrinolytic profiles in patients with severe pulmonary hypertension. Chest. 1996 Sep; 110(3):710-7. PMID: 8797416.
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    62. Lane PA, O'Connell JL, Lear JL, Rogers ZR, Woods GM, Hassell KL, Wethers DL, Luckey DW, Buchanan GR. Functional asplenia in hemoglobin SC disease. Blood. 1995 Apr 15; 85(8):2238-44. PMID: 7718896.
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    63. Santhosh-Kumar CR, Deutsch JC, Hassell KL, Kolhouse NM, Kolhouse JF. Quantitation of red blood cell folates by stable isotope dilution gas chromatography-mass spectrometry utilizing a folate internal standard. Anal Biochem. 1995 Feb 10; 225(1):1-9. PMID: 7778757.
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    64. Santhosh-Kumar CR, Hassell KL, Deutsch JC, Kolhouse JF. Are neuropsychiatric manifestations of folate, cobalamin and pyridoxine deficiency mediated through imbalances in excitatory sulfur amino acids? Med Hypotheses. 1994 Oct; 43(4):239-44. PMID: 7838008.
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    65. Hassell KL, Kressin DC, Neumann A, Ellison R, Marlar RA. Correlation of antiphospholipid antibodies and protein S deficiency with thrombosis in HIV-infected men. Blood Coagul Fibrinolysis. 1994 Aug; 5(4):455-62. PMID: 7841299.
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    66. Santhosh-Kumar CR, Deutsch JC, Kolhouse JC, Hassell KL, Kolhouse JF. Measurement of excitatory sulfur amino acids, cysteine sulfinic acid, cysteic acid, homocysteine sulfinic acid, and homocysteic acid in serum by stable isotope dilution gas chromatography-mass spectrometry and selected ion monitoring. Anal Biochem. 1994 Aug 01; 220(2):249-56. PMID: 7978266.
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    67. Hassell KL, Eckman JR, Lane PA. Acute multiorgan failure syndrome: a potentially catastrophic complication of severe sickle cell pain episodes. Am J Med. 1994 Feb; 96(2):155-62. PMID: 8109600.
      View in: PubMed
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