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Robert M Barkley

TitleClinical Instructor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM - Pharmacology

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Di Giovanni JP, Barkley RM, Jones DNM, Hankin JA, Murphy RC. Tandem Mass Spectrometry and Ion Mobility Reveals Structural Insight into Eicosanoid Product Ion Formation. J Am Soc Mass Spectrom. 2018 Jun; 29(6):1231-1241. PMID: 29687419.
      View in: PubMed
    2. Okuno T, Gijón MA, Zarini S, Martin SA, Barkley RM, Johnson CA, Ohba M, Yokomizo T, Murphy RC. Altered eicosanoid production and phospholipid remodeling during cell culture. J Lipid Res. 2018 Mar; 59(3):542-549. PMID: 29353239.
      View in: PubMed
    3. Murphy RC, Okuno T, Johnson CA, Barkley RM. Determination of Double Bond Positions in Polyunsaturated Fatty Acids Using the Photochemical Paternò-Büchi Reaction with Acetone and Tandem Mass Spectrometry. Anal Chem. 2017 Aug 15; 89(16):8545-8553. PMID: 28719189.
      View in: PubMed
    4. Berry KA, Barkley RM, Berry JJ, Hankin JA, Hoyes E, Brown JM, Murphy RC. Tandem Mass Spectrometry in Combination with Product Ion Mobility for the Identification of Phospholipids. Anal Chem. 2017 01 03; 89(1):916-921. PMID: 27958700.
      View in: PubMed
    5. Hankin JA, Barkley RM, Zemski-Berry K, Deng Y, Murphy RC. Mass Spectrometric Collisional Activation and Product Ion Mobility of Human Serum Neutral Lipid Extracts. Anal Chem. 2016 06 21; 88(12):6274-82. PMID: 27213895.
      View in: PubMed
    6. Shewale SV, Boudyguina E, Zhu X, Shen L, Hutchins PM, Barkley RM, Murphy RC, Parks JS. Botanical oils enriched in n-6 and n-3 FADS2 products are equally effective in preventing atherosclerosis and fatty liver. J Lipid Res. 2015 Jun; 56(6):1191-205. PMID: 25921305; PMCID: PMC4442876.
    7. Li X, Ballantyne LL, Che X, Mewburn JD, Kang JX, Barkley RM, Murphy RC, Yu Y, Funk CD. Endogenously generated omega-3 fatty acids attenuate vascular inflammation and neointimal hyperplasia by interaction with free fatty acid receptor 4 in mice. J Am Heart Assoc. 2015 Apr 06; 4(4). PMID: 25845931; PMCID: PMC4579939.
    8. Hankin JA, Murphy RC, Barkley RM, Gijón MA. Ion Mobility and Tandem Mass Spectrometry of Phosphatidylglycerol and Bis(monoacylglycerol)phosphate (BMP). Int J Mass Spectrom. 2015 Feb 15; 378:255-263. PMID: 25883529.
      View in: PubMed
    9. Gorden DL, Myers DS, Ivanova PT, Fahy E, Maurya MR, Gupta S, Min J, Spann NJ, McDonald JG, Kelly SL, Duan J, Sullards MC, Leiker TJ, Barkley RM, Quehenberger O, Armando AM, Milne SB, Mathews TP, Armstrong MD, Li C, Melvin WV, Clements RH, Washington MK, Mendonsa AM, Witztum JL, Guan Z, Glass CK, Murphy RC, Dennis EA, Merrill AH, Russell DW, Subramaniam S, Brown HA. Biomarkers of NAFLD progression: a lipidomics approach to an epidemic. J Lipid Res. 2015 Mar; 56(3):722-36. PMID: 25598080; PMCID: PMC4340319.
    10. Wysoczynski CL, Roemer SC, Dostal V, Barkley RM, Churchill ME, Malarkey CS. Reversed-phase ion-pair liquid chromatography method for purification of duplex DNA with single base pair resolution. Nucleic Acids Res. 2013 Nov; 41(20):e194. PMID: 24013567; PMCID: PMC3814375.
    11. Wooding KM, Barkley RM, Hankin JA, Johnson CA, Bradford AP, Santoro N, Murphy RC. Mechanism of formation of the major estradiol product ions following collisional activation of the molecular anion in a tandem quadrupole mass spectrometer. J Am Soc Mass Spectrom. 2013 Oct; 24(10):1451-5. PMID: 23955001; PMCID: PMC3786604.
    12. Berry KA, Hankin JA, Barkley RM, Spraggins JM, Caprioli RM, Murphy RC. MALDI imaging of lipid biochemistry in tissues by mass spectrometry. Chem Rev. 2011 Oct 12; 111(10):6491-512. PMID: 21942646; PMCID: PMC3199966.
    13. Leiker TJ, Barkley RM, Murphy RC. Analysis of Diacylglycerol Molecular Species in Cellular Lipid Extracts by Normal-Phase LC-Electrospray Mass Spectrometry. Int J Mass Spectrom. 2011 Aug 15; 305(2-3):103-109. PMID: 21860599.
      View in: PubMed
    14. Murphy RC, Leiker TJ, Barkley RM. Glycerolipid and cholesterol ester analyses in biological samples by mass spectrometry. Biochim Biophys Acta. 2011 Nov; 1811(11):776-83. PMID: 21757029; PMCID: PMC3205286.
    15. Murphy RC, Hankin JA, Barkley RM, Zemski Berry KA. MALDI imaging of lipids after matrix sublimation/deposition. Biochim Biophys Acta. 2011 Nov; 1811(11):970-5. PMID: 21571091; PMCID: PMC3202086.
    16. Berry KA, Li B, Reynolds SD, Barkley RM, Gijón MA, Hankin JA, Henson PM, Murphy RC. MALDI imaging MS of phospholipids in the mouse lung. J Lipid Res. 2011 Aug; 52(8):1551-60. PMID: 21508254; PMCID: PMC3137021.
    17. Hankin JA, Farias SE, Barkley RM, Heidenreich K, Frey LC, Hamazaki K, Kim HY, Murphy RC. MALDI mass spectrometric imaging of lipids in rat brain injury models. J Am Soc Mass Spectrom. 2011 Jun; 22(6):1014-21. PMID: 21953042; PMCID: PMC4537074.
    18. Quehenberger O, Armando AM, Brown AH, Milne SB, Myers DS, Merrill AH, Bandyopadhyay S, Jones KN, Kelly S, Shaner RL, Sullards CM, Wang E, Murphy RC, Barkley RM, Leiker TJ, Raetz CR, Guan Z, Laird GM, Six DA, Russell DW, McDonald JG, Subramaniam S, Fahy E, Dennis EA. Lipidomics reveals a remarkable diversity of lipids in human plasma. J Lipid Res. 2010 Nov; 51(11):3299-305. PMID: 20671299; PMCID: PMC2952570.
    19. Parker SK, Barkley RM, Rino JG, Vasil ML. Mycobacterium tuberculosis Rv3802c encodes a phospholipase/thioesterase and is inhibited by the antimycobacterial agent tetrahydrolipstatin. PLoS One. 2009; 4(1):e4281. PMID: 19169353; PMCID: PMC2625445.
    20. Murphy RC, Hankin JA, Barkley RM. Imaging of lipid species by MALDI mass spectrometry. J Lipid Res. 2009 Apr; 50 Suppl:S317-22. PMID: 19050313; PMCID: PMC2674737.
    21. McDonald JG, Cummins CL, Barkley RM, Thompson BM, Lincoln HA. Identification and quantitation of sorbitol-based nuclear clarifying agents extracted from common laboratory and consumer plasticware made of polypropylene. Anal Chem. 2008 Jul 15; 80(14):5532-41. PMID: 18533681; PMCID: PMC2727714.
    22. Hutchins PM, Barkley RM, Murphy RC. Separation of cellular nonpolar neutral lipids by normal-phase chromatography and analysis by electrospray ionization mass spectrometry. J Lipid Res. 2008 Apr; 49(4):804-13. PMID: 18223242; PMCID: PMC2367097.
    23. Hankin JA, Barkley RM, Murphy RC. Sublimation as a method of matrix application for mass spectrometric imaging. J Am Soc Mass Spectrom. 2007 Sep; 18(9):1646-52. PMID: 17659880; PMCID: PMC2042488.
    24. Murphy RC, James PF, McAnoy AM, Krank J, Duchoslav E, Barkley RM. Detection of the abundance of diacylglycerol and triacylglycerol molecular species in cells using neutral loss mass spectrometry. Anal Biochem. 2007 Jul 01; 366(1):59-70. PMID: 17442253; PMCID: PMC2034497.
    25. Krank J, Murphy RC, Barkley RM, Duchoslav E, McAnoy A. Qualitative analysis and quantitative assessment of changes in neutral glycerol lipid molecular species within cells. Methods Enzymol. 2007; 432:1-20. PMID: 17954211.
      View in: PubMed
    26. Murphy RC, Barkley RM, Zemski Berry K, Hankin J, Harrison K, Johnson C, Krank J, McAnoy A, Uhlson C, Zarini S. Electrospray ionization and tandem mass spectrometry of eicosanoids. Anal Biochem. 2005 Nov 01; 346(1):1-42. PMID: 15961057.
      View in: PubMed
    27. Murphy RC, Raetz CR, Reynolds CM, Barkley RM. Mass spectrometry advances in lipidomica: collision-induced decomposition of Kdo2-lipid A. Prostaglandins Other Lipid Mediat. 2005 Sep; 77(1-4):131-40. PMID: 16099398; PMCID: PMC4535423.
    28. Quittnat F, Nishikawa Y, Stedman TT, Voelker DR, Choi JY, Zahn MM, Murphy RC, Barkley RM, Pypaert M, Joiner KA, Coppens I. On the biogenesis of lipid bodies in ancient eukaryotes: synthesis of triacylglycerols by a Toxoplasma DGAT1-related enzyme. Mol Biochem Parasitol. 2004 Nov; 138(1):107-22. PMID: 15500922.
      View in: PubMed
    29. Frazey PA, Barkley RM, Sievers RE. Solid-phase microextraction with temperature-programmed desorption for the analysis of iodination disinfection byproducts. Anal Chem. 1998 Feb 01; 70(3):638-44. PMID: 9470491.
      View in: PubMed
    30. Veltkamp PR, Hansen KJ, Barkley RM, Sievers RE. Chromatographic measurement of molecular markers of sources of atmospheric aerosol particles. Environ Geochem Health. 1996 Jun; 18(2):77-80. PMID: 24194378.
      View in: PubMed
    31. Dunham AJ, Barkley RM, Sievers RE. Aqueous nitrite ion determination by selective reduction and gas phase nitric oxide chemiluminescence. Anal Chem. 1995 Jan 01; 67(1):220-4. PMID: 11536661.
      View in: PubMed
    32. Silverstein J, Brion GM, Barkley R, Dunham A, Hurst C, Todd P, Schulz J. Contaminant accumulation in space water recycle systems. Acta Astronaut. 1994 Jul; 33:317-38. PMID: 11539535.
      View in: PubMed
    33. Curtis WE, Muldrow ME, Parker NB, Barkley R, Linas SL, Repine JE. N,N'-dimethylthiourea dioxide formation from N,N'-dimethylthiourea reflects hydrogen peroxide concentrations in simple biological systems. Proc Natl Acad Sci U S A. 1988 May; 85(10):3422-5. PMID: 3130627; PMCID: PMC280223.
    34. Sievers RE, Shearer RL, Barkley RM. Gas chromatographic measurement of carbon monoxide in hydrocarbon matrices with a redox chemiluminescence detector. J Chromatogr. 1987 Jun 12; 395:9-17. PMID: 3624368.
      View in: PubMed
    35. Hutte RS, Williams EJ, Staehelin J, Hawthorne SB, Barkley RM, Sievers RE. Chromatographic analysis of organic compounds in the atmosphere. J Chromatogr. 1984 Oct 19; 302:173-9. PMID: 6209296.
      View in: PubMed
    36. Koch TH, Christy MR, Barkley RM, Sluski R, Bohemier D, Van Buskirk JJ, Kirsch WM. beta-Carboxyaspartic acid. Methods Enzymol. 1984; 107:563-75. PMID: 6390094.
      View in: PubMed
    37. Sievers RE, Barkley RM, Eiceman GA, Shapiro RH, Walton HF, Kolonko KJ, Field LR. Environmental trace analysis of organics in water by glass capillary column chromatography and ancillary techniques. Products of ozonolysis. J Chromatogr. 1977 Nov 11; 142:745-54. PMID: 914947.
      View in: PubMed
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