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Nathan Clark

TitleLecturer
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOP-PROFESSIONAL PHARM EDUC

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Ortel TL, Neumann I, Ageno W, Beyth R, Clark NP, Cuker A, Hutten BA, Jaff MR, Manja V, Schulman S, Thurston C, Vedantham S, Verhamme P, Witt DM, D Florez I, Izcovich A, Nieuwlaat R, Ross S, J Schünemann H, Wiercioch W, Zhang Y, Zhang Y. American Society of Hematology 2020 guidelines for management of venous thromboembolism: treatment of deep vein thrombosis and pulmonary embolism. Blood Adv. 2020 Oct 13; 4(19):4693-4738. PMID: 33007077.
      View in: PubMed
    2. Delate T, Charlu M, Zhu S, Pai A, Clark NP, Witt DM, King JM, King JB. Temporal trends in first-line outpatient anticoagulation treatment for cancer-associated venous thromboembolism. Thromb Res. 2020 12; 196:367-370. PMID: 32979674.
      View in: PubMed
    3. Barnes GD, Burnett A, Allen A, Blumenstein M, Clark NP, Cuker A, Dager WE, Deitelzweig SB, Ellsworth S, Garcia D, Kaatz S, Minichiello T. Thromboembolism and anticoagulant therapy during the COVID-19 pandemic: interim clinical guidance from the anticoagulation forum. J Thromb Thrombolysis. 2020 Jul; 50(1):72-81. PMID: 32440883.
      View in: PubMed
    4. Packard A, Delate T, Martinez K, Clark NP. Adherence to and persistence with direct oral anticoagulant therapy among patients with new onset venous thromboembolism receiving extended anticoagulant therapy and followed by a centralized anticoagulation service. Thromb Res. 2020 09; 193:40-44. PMID: 32521333.
      View in: PubMed
    5. Farrow GS, Delate T, McNeil K, Jones AE, Witt DM, Crowther MA, Clark NP. Vitamin K versus warfarin interruption alone in patients without bleeding and an international normalized ratio > 10. J Thromb Haemost. 2020 05; 18(5):1133-1140. PMID: 32073738.
      View in: PubMed
    6. Khatib R, Ross S, Kennedy SA, Florez ID, Ortel TL, Nieuwlaat R, Neumann I, Witt DM, Schulman S, Manja V, Beyth R, Clark NP, Wiercioch W, Schünemann HJ, Zhang Y. Home vs hospital treatment of low-risk venous thromboembolism: a systematic review and meta-analysis. Blood Adv. 2020 02 11; 4(3):500-513. PMID: 32040553.
      View in: PubMed
    7. Douketis JD, Spyropoulos AC, Duncan J, Carrier M, Le Gal G, Tafur AJ, Vanassche T, Verhamme P, Shivakumar S, Gross PL, Lee AYY, Yeo E, Solymoss S, Kassis J, Le Templier G, Kowalski S, Blostein M, Shah V, MacKay E, Wu C, Clark NP, Bates SM, Spencer FA, Arnaoutoglou E, Coppens M, Arnold DM, Caprini JA, Li N, Moffat KA, Syed S, Schulman S. Perioperative Management of Patients With Atrial Fibrillation Receiving a Direct Oral Anticoagulant. JAMA Intern Med. 2019 Aug 05. PMID: 31380891.
      View in: PubMed
    8. Khatib R, Ludwikowska M, Witt DM, Ansell J, Clark NP, Holbrook A, Wiercioch W, Schünemann H, Nieuwlaat R. Vitamin K for reversal of excessive vitamin K antagonist anticoagulation: a systematic review and meta-analysis. Blood Adv. 2019 03 12; 3(5):789-796. PMID: 30850385.
      View in: PubMed
    9. Clark NP. Role of the anticoagulant monitoring service in 2018: beyond warfarin. Hematology Am Soc Hematol Educ Program. 2018 11 30; 2018(1):348-352. PMID: 30504331.
      View in: PubMed
    10. Witt DM, Nieuwlaat R, Clark NP, Ansell J, Holbrook A, Skov J, Shehab N, Mock J, Myers T, Dentali F, Crowther MA, Agarwal A, Bhatt M, Khatib R, Riva JJ, Zhang Y, Guyatt G. American Society of Hematology 2018 guidelines for management of venous thromboembolism: optimal management of anticoagulation therapy. Blood Adv. 2018 11 27; 2(22):3257-3291. PMID: 30482765.
      View in: PubMed
    11. Hawkins KL, King J, Delate T, Martinez K, McCool K, Clark NP. Pharmacy Technician Management of Stable, In-Range INRs Within a Clinical Pharmacy Anticoagulation Service. J Manag Care Spec Pharm. 2018 Nov; 24(11):1130-1137. PMID: 30362923.
      View in: PubMed
    12. Douketis JD, Spyropoulos AC, Anderson JM, Arnold DM, Bates SM, Blostein M, Carrier M, Caprini JA, Clark NP, Coppens M, Dentali F, Duncan J, Gross PL, Kassis J, Kowalski S, Lee AY, Le Gal G, Le Templier G, Li N, MacKay E, Shah V, Shivakumar S, Solymoss S, Spencer FA, Syed S, Tafur AJ, Vanassche T, Thiele T, Wu C, Yeo E, Schulman S. Erratum to: The Perioperative Anticoagulant Use for Surgery Evaluation (PAUSE) Study for Patients on a Direct Oral Anticoagulant who Need an Elective Surgery or Procedure: Design and Rationale. Thromb Haemost. 2018 Sep; 118(9):1679-1680. PMID: 30216954.
      View in: PubMed
    13. Polnak JF, Delate T, Clark NP. The influence of fibrate initiation on INR and warfarin dose in patients receiving chronic warfarin therapy. J Thromb Thrombolysis. 2018 Aug; 46(2):264-270. PMID: 29681002.
      View in: PubMed
    14. Phelps E, Delate T, Witt DM, Shaw PB, McCool KH, Clark NP. Effect of increased time in the therapeutic range on atrial fibrillation outcomes within a centralized anticoagulation service. Thromb Res. 2018 03; 163:54-59. PMID: 29407629.
      View in: PubMed
    15. Douketis JD, Spyropoulos AC, Anderson JM, Arnold DM, Bates SM, Blostein M, Carrier M, Caprini JA, Clark NP, Coppens M, Dentali F, Duncan J, Gross PL, Kassis J, Kowalski S, Lee AY, Le Gal G, Le Templier G, Li N, MacKay E, Shah V, Shivakumar S, Solymoss S, Spencer FA, Syed S, Tafur AJ, Vanassche T, Thiele T, Wu C, Yeo E, Schulman S. The Perioperative Anticoagulant Use for Surgery Evaluation (PAUSE) Study for Patients on a Direct Oral Anticoagulant Who Need an Elective Surgery or Procedure: Design and Rationale. Thromb Haemost. 2017 12; 117(12):2415-2424. PMID: 29212129.
      View in: PubMed
    16. Delate T, Jones AE, Clark NP, Witt DM. Assessment of the coding accuracy of warfarin-related bleeding events. Thromb Res. 2017 Nov; 159:86-90. PMID: 29035718.
      View in: PubMed
    17. Clark NP, Douketis JD, Hasselblad V, Schulman S, Kindzelski AL, Ortel TL. Predictors of perioperative major bleeding in patients who interrupt warfarin for an elective surgery or procedure: Analysis of the BRIDGE trial. Am Heart J. 2018 Jan; 195:108-114. PMID: 29224638.
      View in: PubMed
    18. Clark NP, Hoang K, Delate T, Horn JR, Witt DM. Warfarin Interaction With Hepatic Cytochrome P-450 Enzyme-Inducing Anticonvulsants. Clin Appl Thromb Hemost. 2018 Jan; 24(1):172-178. PMID: 28118749.
      View in: PubMed
    19. Delate T, Meisinger SM, Witt DM, Jenkins D, Douketis JD, Clark NP. Bridge Therapy Outcomes in Patients With Mechanical Heart Valves. Clin Appl Thromb Hemost. 2017 Nov; 23(8):1036-1041. PMID: 27655997.
      View in: PubMed
    20. Witt DM, Clark NP, Kaatz S, Schnurr T, Ansell JE. Guidance for the practical management of warfarin therapy in the treatment of venous thromboembolism. J Thromb Thrombolysis. 2016 Jan; 41(1):187-205. PMID: 26780746.
      View in: PubMed
    21. Meyer MR, Witt DM, Delate T, Johnson SG, Fang M, Go A, Clark NP. Thrombophilia testing patterns amongst patients with acute venous thromboembolism. Thromb Res. 2015 Dec; 136(6):1160-4. PMID: 26477821.
      View in: PubMed
    22. Witt DM, Clark NP, Martinez K, Schroeder A, Garcia D, Crowther MA, Ageno W, Dentali F, Ye X, Hylek E, Delate T. Risk of thromboembolism, recurrent hemorrhage, and death after warfarin therapy interruption for intracranial hemorrhage. Thromb Res. 2015 Nov; 136(5):1040-4. PMID: 26454758.
      View in: PubMed
    23. Clark NP, Witt DM, Davies LE, Saito EM, McCool KH, Douketis JD, Metz KR, Delate T. Bleeding, Recurrent Venous Thromboembolism, and Mortality Risks During Warfarin Interruption for Invasive Procedures. JAMA Intern Med. 2015 Jul; 175(7):1163-8. PMID: 26010033.
      View in: PubMed
    24. Martinez K, Kosirog E, Billups SJ, Clark NP, Delate T, Witt DM. Clinical outcomes and adherence to guideline recommendations during the initial treatment of acute venous thromboembolism. Ann Pharmacother. 2015 Aug; 49(8):869-75. PMID: 25931575.
      View in: PubMed
    25. Jenner KM, Simmons BJ, Delate T, Clark NP, Kurz D, Witt DM. An Education Program for Patient Self-Management of Warfarin. Perm J. 2015; 19(4):33-8. PMID: 26517434.
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    26. Cho SE, Delate T, Witt DM, Clark NP. Thromboembolic and bleeding outcomes of extended duration low-intensity warfarin following elective total knee arthroplasty. Thromb Res. 2015 Feb; 135(2):267-71. PMID: 25555318.
      View in: PubMed
    27. Riggs CS, Delate T, Clark NP. Supratherapeutic international normalized ratios in warfarin-treated patients who receive a highly potentiating antimicrobial course--reply. JAMA Intern Med. 2014 Jul; 174(7):1200-1. PMID: 25003888.
      View in: PubMed
    28. Clark NP, Delate T, Riggs CS, Witt DM, Hylek EM, Garcia DA, Ageno W, Dentali F, Crowther MA. Warfarin interactions with antibiotics in the ambulatory care setting. JAMA Intern Med. 2014 Mar; 174(3):409-16. PMID: 24445404.
      View in: PubMed
    29. Witt DM, Delate T, Hylek EM, Clark NP, Crowther MA, Dentali F, Ageno W, Martinez KD, Garcia DA. Effect of warfarin on intracranial hemorrhage incidence and fatal outcomes. Thromb Res. 2013; 132(6):770-5. PMID: 24521790.
      View in: PubMed
    30. Witt DM, Delate T, Clark NP, Garcia DA, Hylek EM, Ageno W, Dentali F, Crowther MA. Nonadherence with INR monitoring and anticoagulant complications. Thromb Res. 2013 Aug; 132(2):e124-30. PMID: 23800635.
      View in: PubMed
    31. Clark NP. Frequency of monitoring, non-adherence, and other topics dear to an anticoagulation clinic provider. J Thromb Thrombolysis. 2013 Apr; 35(3):320-4. PMID: 23494486.
      View in: PubMed
    32. Clark NP, Cho SE, Delate T, Witt DM. Thromboembolic and bleeding outcomes of low-intensity warfarin thromboprophylaxis following elective total hip arthroplasty. Thromb Res. 2013 May; 131(5):390-5. PMID: 23522854.
      View in: PubMed
    33. Simmons BJ, Jenner KM, Delate T, Clark NP, Kurz D, Witt DM. Pilot study of a novel patient self-management program for warfarin therapy using venipuncture-acquired international normalized ratio monitoring. Pharmacotherapy. 2012 Dec; 32(12):1078-84. PMID: 23112110.
      View in: PubMed
    34. Witt DM, Delate T, Garcia DA, Clark NP, Hylek EM, Ageno W, Dentali F, Crowther MA. Risk of thromboembolism, recurrent hemorrhage, and death after warfarin therapy interruption for gastrointestinal tract bleeding. Arch Intern Med. 2012 Oct 22; 172(19):1484-91. PMID: 22987143.
      View in: PubMed
    35. Dentali F, Marchesi C, Giorgi Pierfranceschi M, Crowther M, Garcia D, Hylek E, Witt DM, Clark NP, Squizzato A, Imberti D, Ageno W. Safety of prothrombin complex concentrates for rapid anticoagulation reversal of vitamin K antagonists. A meta-analysis. Thromb Haemost. 2011 Sep; 106(3):429-38. PMID: 21800002.
      View in: PubMed
    36. Crowther MA, Garcia D, Ageno W, Wang L, Witt DM, Clark NP, Blostein MD, Kahn SR, Schulman S, Kovacs M, Rodger MA, Wells P, Anderson D, Ginsberg J, Selby R, Siragusa S, Silingardi M, Dowd MB, Kearon C. Oral vitamin K effectively treats international normalised ratio (INR) values in excess of 10. Results of a prospective cohort study. Thromb Haemost. 2010 Jul; 104(1):118-21. PMID: 20458438.
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    37. Clark NP, Delate T, Cleary SJ, Witt DM. Unfractionated heparin dose requirements targeting intermediate intensity antifactor Xa concentration during pregnancy. Pharmacotherapy. 2010 Apr; 30(4):369-74. PMID: 20334457.
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    38. Clark NP, Delate T, Cleary SJ, Witt DM. Analysis of unfractionated heparin dose requirements to target therapeutic anti-Xa intensity during pregnancy. Thromb Res. 2010 May; 125(5):402-5. PMID: 19699510.
      View in: PubMed
    39. Witt DM, Delate T, Clark NP, Martell C, Tran T, Crowther MA, Garcia DA, Ageno W, Hylek EM. Outcomes and predictors of very stable INR control during chronic anticoagulation therapy. Blood. 2009 Jul 30; 114(5):952-6. PMID: 19439733.
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    40. Crowther MA, Ageno W, Garcia D, Wang L, Witt DM, Clark NP, Blostein MD, Kahn SR, Vesely SK, Schulman S, Kovacs MJ, Rodger MA, Wells P, Anderson D, Ginsberg J, Selby R, Siragusa S, Silingardi M, Dowd MB, Kearon C. Oral vitamin K versus placebo to correct excessive anticoagulation in patients receiving warfarin: a randomized trial. Ann Intern Med. 2009 Mar 03; 150(5):293-300. PMID: 19258557.
      View in: PubMed
    41. Clark NP, Witt DM, Delate T, Trapp M, Garcia D, Ageno W, Hylek EM, Crowther MA. Thromboembolic consequences of subtherapeutic anticoagulation in patients stabilized on warfarin therapy: the low INR study. Pharmacotherapy. 2008 Aug; 28(8):960-7. PMID: 18657012.
      View in: PubMed
    42. Clark NP, Delate T, Witt DM, Parker S, McDuffie R. A descriptive evaluation of unfractionated heparin use during pregnancy. J Thromb Thrombolysis. 2009 Apr; 27(3):267-73. PMID: 18327536.
      View in: PubMed
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