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Andrii Rozhok

TitleResearch Instructor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-DERM GATES CENTER

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Rozhok AI, Silberman RE, Higa KC, Liggett LA, Amon A, DeGregori J. A somatic evolutionary model of the dynamics of aneuploid cells during hematopoietic reconstitution. Sci Rep. 2020 07 22; 10(1):12198. PMID: 32699207.
      View in: PubMed
    2. Rozhok AI, DeGregori J. The three dimensions of somatic evolution: Integrating the role of genetic damage, life-history traits, and aging in carcinogenesis. Evol Appl. 2020 Aug; 13(7):1569-1580. PMID: 32821273.
      View in: PubMed
    3. Rozhok A, DeGregori J. Somatic maintenance impacts the evolution of mutation rate. BMC Evol Biol. 2019 08 23; 19(1):172. PMID: 31443631.
      View in: PubMed
    4. Rozhok A, DeGregori J. A generalized theory of age-dependent carcinogenesis. Elife. 2019 04 29; 8. PMID: 31034356.
      View in: PubMed
    5. Pham-Danis C, Gehrke S, Danis E, Rozhok AI, Daniels MW, Gao D, Collins C, Paola JTD, D'Alessandro A, DeGregori J. Urea Cycle Sustains Cellular Energetics upon EGFR Inhibition in EGFR-Mutant NSCLC. Mol Cancer Res. 2019 06; 17(6):1351-1364. PMID: 30808730.
      View in: PubMed
    6. Tu MM, Lee FYF, Jones RT, Kimball AK, Saravia E, Graziano RF, Coleman B, Menard K, Yan J, Michaud E, Chang H, Abdel-Hafiz HA, Rozhok AI, Duex JE, Agarwal N, Chauca-Diaz A, Johnson LK, Ng TL, Cambier JC, Clambey ET, Costello JC, Korman AJ, Theodorescu D. Targeting DDR2 enhances tumor response to anti-PD-1 immunotherapy. Sci Adv. 2019 02; 5(2):eaav2437. PMID: 30801016.
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    7. Kozeretska IA, Shulha VI, Serga SV, Rozhok AI, Protsenko OV, Lau NC. A rapid change in P-element-induced hybrid dysgenesis status in Ukrainian populations of Drosophila melanogaster. Biol Lett. 2018 08; 14(8). PMID: 30135116.
      View in: PubMed
    8. Zhang G, Scarborough H, Kim J, Rozhok AI, Chen YA, Zhang X, Song L, Bai Y, Fang B, Liu RZ, Koomen J, Tan AC, Degregori J, Haura EB. Coupling an EML4-ALK-centric interactome with RNA interference identifies sensitizers to ALK inhibitors. Sci Signal. 2016 10 18; 9(450):rs12. PMID: 27811184.
      View in: PubMed
    9. Gregory MA, D'Alessandro A, Alvarez-Calderon F, Kim J, Nemkov T, Adane B, Rozhok AI, Kumar A, Kumar V, Pollyea DA, Wempe MF, Jordan CT, Serkova NJ, Tan AC, Hansen KC, DeGregori J. ATM/G6PD-driven redox metabolism promotes FLT3 inhibitor resistance in acute myeloid leukemia. Proc Natl Acad Sci U S A. 2016 10 25; 113(43):E6669-E6678. PMID: 27791036.
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    10. Rozhok AI, DeGregori J. The evolution of lifespan and age-dependent cancer risk. Trends Cancer. 2016 10; 2(10):552-560. PMID: 28439564.
      View in: PubMed
    11. Marusyk A, Tabassum DP, Janiszewska M, Place AE, Trinh A, Rozhok AI, Pyne S, Guerriero JL, Shu S, Ekram M, Ishkin A, Cahill DP, Nikolsky Y, Chan TA, Rimawi MF, Hilsenbeck S, Schiff R, Osborne KC, Letai A, Polyak K. Spatial Proximity to Fibroblasts Impacts Molecular Features and Therapeutic Sensitivity of Breast Cancer Cells Influencing Clinical Outcomes. Cancer Res. 2016 11 15; 76(22):6495-6506. PMID: 27671678.
      View in: PubMed
    12. Rozhok AI, Salstrom JL, DeGregori J. Stochastic modeling reveals an evolutionary mechanism underlying elevated rates of childhood leukemia. Proc Natl Acad Sci U S A. 2016 Jan 26; 113(4):1050-5. PMID: 26755588.
      View in: PubMed
    13. Rozhok AI, DeGregori J. Toward an evolutionary model of cancer: Considering the mechanisms that govern the fate of somatic mutations. Proc Natl Acad Sci U S A. 2015 Jul 21; 112(29):8914-21. PMID: 26195756.
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    14. Rozhok AI, Wahl GM, DeGregori J. A Critical Examination of the "Bad Luck" Explanation of Cancer Risk. Cancer Prev Res (Phila). 2015 Sep; 8(9):762-4. PMID: 26122457.
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    15. Fleenor CJ, Rozhok AI, Zaberezhnyy V, Mathew D, Kim J, Tan AC, Bernstein ID, DeGregori J. Contrasting roles for C/EBPa and Notch in irradiation-induced multipotent hematopoietic progenitor cell defects. Stem Cells. 2015 Apr; 33(4):1345-58. PMID: 25546133.
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    16. Henry CJ, Sedjo RL, Rozhok A, Salstrom J, Ahnen D, Levin TR, D'Agostino R, Haffner S, DeGregori J, Byers T. Lack of significant association between serum inflammatory cytokine profiles and the presence of colorectal adenoma. BMC Cancer. 2015 Mar 14; 15:123. PMID: 25884547.
      View in: PubMed
    17. Rozhok AI, Salstrom JL, DeGregori J. Stochastic modeling indicates that aging and somatic evolution in the hematopoetic system are driven by non-cell-autonomous processes. Aging (Albany NY). 2014 Dec; 6(12):1033-48. PMID: 25564763.
      View in: PubMed
    18. Rozhok AI, Ievdokymenko KS, Kozeretska IA. On the persistence of P element in cultured lineages of Drosophila melanogaster. Tsitol Genet. 2012 Jul-Aug; 46(4):55-8. PMID: 23074963.
      View in: PubMed
    19. Redchuk TA, Rozhok AI, Zhuk OW, Kozeretska IA, Mousseau TA. DNA methylation in Drosophila melanogaster may depend on lineage heterogeneity. Tsitol Genet. 2012 Jan-Feb; 46(1):75-9. PMID: 22420223.
      View in: PubMed
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