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Richard J Martin

TitleAffiliate - NJH
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-MED

    Collapse Research 
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    U10HD029071     (MARTIN, RICHARD J.)Sep 30, 1991 - Aug 31, 2000
    NIH/NICHD
    COLLABORATIVE HOME INFANT MONITORING EVALUATION (CHIME)
    Role: Principal Investigator
    U10HL051834     (MARTIN, RICHARD J)Sep 30, 1993 - Aug 31, 2005
    NIH/NHLBI
    ASTHMA CLINICAL RESEARCH NETWORK (ACRN)
    Role: Principal Investigator
    R01HL050527     (MARTIN, RICHARD JOHN)Jan 1, 1995 - Mar 31, 2010
    NIH/NHLBI
    Airway-Central Nervous System Control
    Role: Principal Investigator
    R01HL056470     (PRAKASH, Y. S.)May 3, 1996 - Nov 30, 2020
    NIH/NHLBI
    Neonatal Modulation of Airway Contractility
    Role: Co-Principal Investigator
    R01HL062527     (MARTIN, RICHARD JOHN)Apr 1, 1999 - Jun 30, 2008
    NIH/NHLBI
    DEVELOPMENTAL REGULATION OF HYPERCAPNIC RESPONSES
    Role: Principal Investigator
    R56AI047194     (MARTIN, RICHARD JOHN)Mar 1, 2000 - Jun 30, 2013
    NIH/NIAID
    Modulation of levamisole receptors: Pharmacological Diversity of Clade III nAChRs
    Role: Principal Investigator
    R01AI047194     (MARTIN, RICHARD JOHN)Mar 1, 2000 - Apr 30, 2022
    NIH/NIAID
    Pharmacological Diversity of nAChRs in Clade III Nematodes: Brugia malayi
    Role: Principal Investigator
    R01HL064804     (MARTIN, RICHARD J)Apr 1, 2000 - Mar 31, 2004
    NIH/NHLBI
    ASTHMA CHRONOBIOLOGY: CENTRAL AND LUNG INTERACTIONS
    Role: Principal Investigator
    U10HL074073     (MARTIN, RICHARD J)Sep 15, 2003 - Jul 31, 2010
    NIH/NHLBI
    Innovative Investigations and Therapies for Asthma
    Role: Principal Investigator
    P01HL073907     (MARTIN, RICHARD J)Jul 5, 2004 - Mar 31, 2010
    NIH/NHLBI
    The Effect of Mycoplasma on Chronic Asthma
    Role: Principal Investigator
    T32HD060537     (MARTIN, RICHARD JOHN)Sep 3, 2009 - Apr 30, 2019
    NIH/NICHD
    Training in Neonatal Research
    Role: Principal Investigator
    P30HL101294     (MARTIN, RICHARD J)Sep 30, 2009 - Aug 31, 2012
    NIH/NHLBI
    Fostering collaborations and the career of a newly recruited pulmonary scientist
    Role: Principal Investigator
    U10HL098075     (WECHSLER, MICHAEL E)Sep 30, 2009 - Jun 30, 2016
    NIH/NHLBI
    Clinical Centers for the NHLBI Asthma Network (AsthmaNet)
    Role: Co-Principal Investigator
    R21HL098628     (MARTIN, RICHARD JOHN)Jul 1, 2010 - Jun 30, 2012
    NIH/NHLBI
    Cytokines and Neonatal Respiratory Control
    Role: Principal Investigator
    R13AI096749     (MARTIN, RICHARD JOHN)Aug 15, 2011 - Jul 31, 2012
    NIH/NIAID
    Membrane Ion-channels in Helminth Parasites: Anthelmintic Resistance and Sites of
    Role: Principal Investigator
    R13HL118931     (MARTIN, RICHARD J)May 1, 2013 - Apr 30, 2014
    NIH/NHLBI
    Aspen Lung Conference: The Lung Microbiome: A New Frontier in Pulmonary Medicine
    Role: Principal Investigator
    R03HD078528     (MARTIN, RICHARD JOHN)Aug 1, 2014 - Jul 31, 2016
    NIH/NICHD
    Patterns of Hypoxia and Mortality in the SUPPORT Trial Cohort
    Role: Principal Investigator
    R01HL126895     (ALAM, RAFEUL)Apr 20, 2016 - Mar 31, 2020
    NIH/NHLBI
    Airway Th2Th17 Cells in Refractory Asthma
    Role: Co-Principal Investigator
    U01HL133643     (HIBBS, ANNA MARIA)Sep 1, 2016 - Jun 30, 2021
    NIH/NHLBI
    Hibbs -Association Between Intermittent Hypoxia and Later Respiratory Morbidity
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Ito Y, Schaefer N, Sanchez A, Francisco D, Alam R, Martin RJ, Ledford JG, Stevenson C, Jiang D, Li L, Kraft M, Chu HW. Toll-Interacting Protein, Tollip, Inhibits IL-13-Mediated Pulmonary Eosinophilic Inflammation in Mice. J Innate Immun. 2018; 10(2):106-118. PMID: 29393212.
      View in: PubMed
    2. Hillyer EV, Price DB, Chrystyn H, Martin RJ, Israel E, van Aalderen WMC, Papi A, Usmani OS, Roche N. Harmonizing the Nomenclature for Therapeutic Aerosol Particle Size: A Proposal. J Aerosol Med Pulm Drug Deliv. 2018 Apr; 31(2):111-113. PMID: 29182483.
      View in: PubMed
    3. Sonnappa S, McQueen B, Postma DS, Martin RJ, Roche N, Grigg J, Guilbert T, Gouder C, Pizzichini E, Niimi A, Phipatanakul W, Chisholm A, Dandurand RJ, Kaplan A, Israel E, Papi A, van Aalderen WMC, Usmani OS, Price DB. Extrafine Versus Fine Inhaled Corticosteroids in Relation to Asthma Control: A Systematic Review and Meta-Analysis of Observational Real-Life Studies. J Allergy Clin Immunol Pract. 2018 May - Jun; 6(3):907-915.e7. PMID: 28941668.
      View in: PubMed
    4. Goleva E, Harris JK, Robertson CE, Jackson LP, Martin RJ, Leung DYM. Airway microbiome and responses to corticosteroids in corticosteroid-resistant asthma patients treated with acid suppression medications. J Allergy Clin Immunol. 2017 Sep; 140(3):860-862.e1. PMID: 28477847.
      View in: PubMed
    5. Dollerup J, Vestbo J, Murray-Thomas T, Kaplan A, Martin RJ, Pizzichini E, Pizzichini MMM, Burden A, Martin J, Price DB. Cardiovascular risks in smokers treated with nicotine replacement therapy: a historical cohort study. Clin Epidemiol. 2017; 9:231-243. PMID: 28490903.
      View in: PubMed
    6. Liu S, Verma M, Michalec L, Liu W, Sripada A, Rollins D, Good J, Ito Y, Chu H, Gorska MM, Martin RJ, Alam R. Steroid resistance of airway type 2 innate lymphoid cells from patients with severe asthma: The role of thymic stromal lymphopoietin. J Allergy Clin Immunol. 2018 Jan; 141(1):257-268.e6. PMID: 28433687.
      View in: PubMed
    7. Yang IV, Richards A, Davidson EJ, Stevens AD, Kolakowski CA, Martin RJ, Schwartz DA. The Nasal Methylome: A Key to Understanding Allergic Asthma. Am J Respir Crit Care Med. 2017 03 15; 195(6):829-831. PMID: 28294656.
      View in: PubMed
    8. Postma DS, Dekhuijzen R, van der Molen T, Martin RJ, van Aalderen W, Roche N, Guilbert TW, Israel E, van Eickels D, Khalid JM, Herings RM, Overbeek JA, Miglio C, Thomas V, Hutton C, Hillyer EV, Price DB. Asthma-Related Outcomes in Patients Initiating Extrafine Ciclesonide or Fine-Particle Inhaled Corticosteroids. Allergy Asthma Immunol Res. 2017 Mar; 9(2):116-125. PMID: 28102056.
      View in: PubMed
    9. Alam R, Good J, Rollins D, Verma M, Chu H, Pham TH, Martin RJ. Airway and serum biochemical correlates of refractory neutrophilic asthma. J Allergy Clin Immunol. 2017 Oct; 140(4):1004-1014.e13. PMID: 28163052.
      View in: PubMed
    10. Katial RK, Bensch GW, Busse WW, Chipps BE, Denson JL, Gerber AN, Jacobs JS, Kraft M, Martin RJ, Nair P, Wechsler ME. Changing Paradigms in the Treatment of Severe Asthma: The Role of Biologic Therapies. J Allergy Clin Immunol Pract. 2017 Mar - Apr; 5(2S):S1-S14. PMID: 28143691.
      View in: PubMed
    11. Guilbert TW, Colice G, Grigg J, van Aalderen W, Martin RJ, Israel E, Postma DS, Roche N, Phipatanakul W, Hillyer EV, Evans JM, Dolovich MB, Price DB. Real-Life Outcomes for Patients with Asthma Prescribed Spacers for Use with Either Extrafine- or Fine-Particle Inhaled Corticosteroids. J Allergy Clin Immunol Pract. 2017 Jul - Aug; 5(4):1040-1049.e4. PMID: 28110057.
      View in: PubMed
    12. Dylag AM, Mayer CA, Raffay TM, Martin RJ, Jafri A, MacFarlane PM. Long-term effects of recurrent intermittent hypoxia and hyperoxia on respiratory system mechanics in neonatal mice. Pediatr Res. 2017 Apr; 81(4):565-571. PMID: 27842056.
      View in: PubMed
    13. Durack J, Lynch SV, Nariya S, Bhakta NR, Beigelman A, Castro M, Dyer AM, Israel E, Kraft M, Martin RJ, Mauger DT, Rosenberg SR, Sharp-King T, White SR, Woodruff PG, Avila PC, Denlinger LC, Holguin F, Lazarus SC, Lugogo N, Moore WC, Peters SP, Que L, Smith LJ, Sorkness CA, Wechsler ME, Wenzel SE, Boushey HA, Huang YJ. Features of the bronchial bacterial microbiome associated with atopy, asthma, and responsiveness to inhaled corticosteroid treatment. J Allergy Clin Immunol. 2017 Jul; 140(1):63-75. PMID: 27838347.
      View in: PubMed
    14. Vogel ER, Britt RD, Faksh A, Kuipers I, Pandya H, Prakash YS, Martin RJ, Pabelick CM. Moderate hyperoxia induces extracellular matrix remodeling by human fetal airway smooth muscle cells. Pediatr Res. 2017 Feb; 81(2):376-383. PMID: 27925619.
      View in: PubMed
    15. Yang IV, Pedersen BS, Liu AH, O'Connor GT, Pillai D, Kattan M, Misiak RT, Gruchalla R, Szefler SJ, Khurana Hershey GK, Kercsmar C, Richards A, Stevens AD, Kolakowski CA, Makhija M, Sorkness CA, Krouse RZ, Visness C, Davidson EJ, Hennessy CE, Martin RJ, Togias A, Busse WW, Schwartz DA. The nasal methylome and childhood atopic asthma. J Allergy Clin Immunol. 2017 May; 139(5):1478-1488. PMID: 27745942.
      View in: PubMed
    16. Liu W, Liu S, Verma M, Zafar I, Good JT, Rollins D, Groshong S, Gorska MM, Martin RJ, Alam R. Mechanism of TH2/TH17-predominant and neutrophilic TH2/TH17-low subtypes of asthma. J Allergy Clin Immunol. 2017 May; 139(5):1548-1558.e4. PMID: 27702673.
      View in: PubMed
    17. Raffay TM, Dylag AM, Di Fiore JM, Smith LA, Einisman HJ, Li Y, Lakner MM, Khalil AM, MacFarlane PM, Martin RJ, Gaston B. S-Nitrosoglutathione Attenuates Airway Hyperresponsiveness in Murine Bronchopulmonary Dysplasia. Mol Pharmacol. 2016 10; 90(4):418-26. PMID: 27484068.
      View in: PubMed
    18. van der Molen T, Postma DS, Martin RJ, Herings RM, Overbeek JA, Thomas V, Miglio C, Dekhuijzen R, Roche N, Guilbert T, Israel E, van Aalderen W, Hillyer EV, van Rysewyk S, Price DB. Erratum to: Effectiveness of initiating extrafine-particle versus fine-particle inhaled corticosteroids as asthma therapy in the Netherlands. BMC Pulm Med. 2016 Jul 23; 16(1):105. PMID: 27450521; PMCID: PMC4958282.
      View in: PubMed, PubMed Central
    19. van der Molen T, Postma DS, Martin RJ, Herings RM, Overbeek JA, Thomas V, Miglio C, Dekhuijzen R, Roche N, Guilbert T, Israel E, van Aalderen W, Hillyer EV, van Rysewyk S, Price DB. Effectiveness of initiating extrafine-particle versus fine-particle inhaled corticosteroids as asthma therapy in the Netherlands. BMC Pulm Med. 2016 May 17; 16(1):80. PMID: 27184175; PMCID: PMC4869182.
      View in: PubMed, PubMed Central
    20. Guerra S, Vasquez MM, Spangenberg A, Halonen M, Martin RJ. Club cell secretory protein in serum and bronchoalveolar lavage of patients with asthma. J Allergy Clin Immunol. 2016 Sep; 138(3):932-934.e1. PMID: 27315766; PMCID: PMC5014567 [Available on 09/01/17].
      View in: PubMed, PubMed Central
    21. Goleva E, Covar R, Martin RJ, Leung DY. Corticosteroid pharmacokinetic abnormalities in overweight and obese corticosteroid resistant asthmatics. J Allergy Clin Immunol Pract. 2016 Mar-Apr; 4(2):357-60.e2. PMID: 26795244.
      View in: PubMed
    22. Abongwa M, Buxton SK, Robertson AP, Martin RJ. Curiouser and Curiouser: The Macrocyclic Lactone, Abamectin, Is also a Potent Inhibitor of Pyrantel/Tribendimidine Nicotinic Acetylcholine Receptors of Gastro-Intestinal Worms. PLoS One. 2016; 11(1):e0146854. PMID: 26751958; PMCID: PMC4709073.
      View in: PubMed, PubMed Central
    23. Faksh A, Britt RD, Vogel ER, Thompson MA, Pandya HC, Martin RJ, Pabelick CM, Prakash YS. TLR3 activation increases chemokine expression in human fetal airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2016 Jan 15; 310(2):L202-11. PMID: 26589477; PMCID: PMC4719047 [Available on 01/15/17].
      View in: PubMed, PubMed Central
    24. Faksh A, Britt RD, Vogel ER, Kuipers I, Thompson MA, Sieck GC, Pabelick CM, Martin RJ, Prakash YS. Effects of antenatal lipopolysaccharide and postnatal hyperoxia on airway reactivity and remodeling in a neonatal mouse model. Pediatr Res. 2016 Mar; 79(3):391-400. PMID: 26539665; PMCID: PMC4821779.
      View in: PubMed, PubMed Central
    25. Reyburn B, Di Fiore JM, Raffay T, Martin RJ, Prakash YS, Jafri A, MacFarlane PM. The Effect of Continuous Positive Airway Pressure in a Mouse Model of Hyperoxic Neonatal Lung Injury. Neonatology. 2016; 109(1):6-13. PMID: 26394387; PMCID: PMC4654984 [Available on 01/01/17].
      View in: PubMed, PubMed Central
    26. Dunn RM, Lehman E, Chinchilli VM, Martin RJ, Boushey HA, Israel E, Kraft M, Lazarus SC, Lemanske RF, Lugogo NL, Peters SP, Sorkness CA, Szefler S, Wechsler ME. Impact of Age and Sex on Response to Asthma Therapy. Am J Respir Crit Care Med. 2015 Sep 01; 192(5):551-8. PMID: 26068329; PMCID: PMC4595693.
      View in: PubMed, PubMed Central
    27. Britt RD, Thompson MA, Kuipers I, Stewart A, Vogel ER, Thu J, Martin RJ, Pabelick CM, Prakash YS. Soluble guanylate cyclase modulators blunt hyperoxia effects on calcium responses of developing human airway smooth muscle. Am J Physiol Lung Cell Mol Physiol. 2015 Sep 15; 309(6):L537-42. PMID: 26254425; PMCID: PMC4572415.
      View in: PubMed, PubMed Central
    28. Gould NS, Min E, Huang J, Chu HW, Good J, Martin RJ, Day BJ. Glutathione Depletion Accelerates Cigarette Smoke-Induced Inflammation and Airspace Enlargement. Toxicol Sci. 2015 Oct; 147(2):466-74. PMID: 26149495; PMCID: PMC4707200 [Available on 10/01/16].
      View in: PubMed, PubMed Central
    29. Thompson MA, Britt RD, Kuipers I, Stewart A, Thu J, Pandya HC, MacFarlane P, Pabelick CM, Martin RJ, Prakash YS. cAMP-mediated secretion of brain-derived neurotrophic factor in developing airway smooth muscle. Biochim Biophys Acta. 2015 Oct; 1853(10 Pt A):2506-14. PMID: 26112987; PMCID: PMC4558218 [Available on 10/01/16].
      View in: PubMed, PubMed Central
    30. Israel E, Roche N, Martin RJ, Colice G, Dorinsky PM, Postma DS, Guilbert TW, van Aalderen WM, Grigg J, Hillyer EV, Burden A, von Ziegenweidt J, Thomas V, Price DB. Increased Dose of Inhaled Corticosteroid versus Add-On Long-acting ß-Agonist for Step-Up Therapy in Asthma. Ann Am Thorac Soc. 2015 Jun; 12(6):798-806. PMID: 25756308.
      View in: PubMed
    31. Britt RD, Faksh A, Vogel ER, Thompson MA, Chu V, Pandya HC, Amrani Y, Martin RJ, Pabelick CM, Prakash YS. Vitamin D attenuates cytokine-induced remodeling in human fetal airway smooth muscle cells. J Cell Physiol. 2015 Jun; 230(6):1189-98. PMID: 25204635; PMCID: PMC4344421.
      View in: PubMed, PubMed Central
    32. van Aalderen WM, Grigg J, Guilbert TW, Roche N, Israel E, Martin RJ, Colice G, Postma DS, Hillyer EV, Burden A, Thomas V, von Ziegenweidt J, Price D. Small-particle Inhaled Corticosteroid as First-line or Step-up Controller Therapy in Childhood Asthma. J Allergy Clin Immunol Pract. 2015 Sep-Oct; 3(5):721-31.e16. PMID: 26032474.
      View in: PubMed
    33. Onugha H, MacFarlane PM, Mayer CA, Abrah A, Jafri A, Martin RJ. Airway Hyperreactivity Is Delayed after Mild Neonatal Hyperoxic Exposure. Neonatology. 2015; 108(1):65-72. PMID: 26021677; PMCID: PMC4475446.
      View in: PubMed, PubMed Central
    34. Mayer CA, Martin RJ, MacFarlane PM. Increased airway reactivity in a neonatal mouse model of continuous positive airway pressure. Pediatr Res. 2015 Aug; 78(2):145-51. PMID: 25950451; PMCID: PMC4506702.
      View in: PubMed, PubMed Central
    35. Roche N, Postma DS, Colice G, Burden A, Guilbert TW, Israel E, Martin RJ, van Aalderen WM, Grigg J, Hillyer EV, von Ziegenweidt J, Price DB. Differential effects of inhaled corticosteroids in smokers/ex-smokers and nonsmokers with asthma. Am J Respir Crit Care Med. 2015 Apr 15; 191(8):960-4. PMID: 25876207.
      View in: PubMed
    36. Christianson CA, Goplen NP, Zafar I, Irvin C, Good JT, Rollins DR, Gorentla B, Liu W, Gorska MM, Chu H, Martin RJ, Alam R. Persistence of asthma requires multiple feedback circuits involving type 2 innate lymphoid cells and IL-33. J Allergy Clin Immunol. 2015 Jul; 136(1):59-68.e14. PMID: 25617223.
      View in: PubMed
    37. Martin YN, Manlove L, Dong J, Carey WA, Thompson MA, Pabelick CM, Pandya HC, Martin RJ, Wigle DA, Prakash YS. Hyperoxia-induced changes in estradiol metabolism in postnatal airway smooth muscle. Am J Physiol Lung Cell Mol Physiol. 2015 Jan 15; 308(2):L141-6. PMID: 25399436; PMCID: PMC4338940.
      View in: PubMed, PubMed Central
    38. Postma DS, Roche N, Colice G, Israel E, Martin RJ, van Aalderen WM, Grigg J, Burden A, Hillyer EV, von Ziegenweidt J, Gopalan G, Price D. Comparing the effectiveness of small-particle versus large-particle inhaled corticosteroid in COPD. Int J Chron Obstruct Pulmon Dis. 2014; 9:1163-86. PMID: 25378918; PMCID: PMC4207569.
      View in: PubMed, PubMed Central
    39. Martin RJ, Price D, Roche N, Israel E, van Aalderen WM, Grigg J, Postma DS, Guilbert TW, Hillyer EV, Burden A, von Ziegenweidt J, Colice G. Cost-effectiveness of initiating extrafine- or standard size-particle inhaled corticosteroid for asthma in two health-care systems: a retrospective matched cohort study. NPJ Prim Care Respir Med. 2014 Oct 09; 24:14081. PMID: 25297072; PMCID: PMC4373495.
      View in: PubMed, PubMed Central
    40. Rollins DR, Good JT, Martin RJ. The role of atypical infections and macrolide therapy in patients with asthma. J Allergy Clin Immunol Pract. 2014 Sep-Oct; 2(5):511-7. PMID: 25213043.
      View in: PubMed
    41. Irvin C, Zafar I, Good J, Rollins D, Christianson C, Gorska MM, Martin RJ, Alam R. Increased frequency of dual-positive TH2/TH17 cells in bronchoalveolar lavage fluid characterizes a population of patients with severe asthma. J Allergy Clin Immunol. 2014 Nov; 134(5):1175-1186.e7. PMID: 25042748.
      View in: PubMed
    42. Raffay T, Kc P, Reynolds J, Di Fiore J, MacFarlane P, Martin RJ. Repeated ß2-adrenergic receptor agonist therapy attenuates the response to rescue bronchodilation in a hyperoxic newborn mouse model. Neonatology. 2014; 106(2):126-32. PMID: 24969536; PMCID: PMC4134388.
      View in: PubMed, PubMed Central
    43. Wang H, Jafri A, Martin RJ, Nnanabu J, Farver C, Prakash YS, MacFarlane PM. Severity of neonatal hyperoxia determines structural and functional changes in developing mouse airway. Am J Physiol Lung Cell Mol Physiol. 2014 Aug 15; 307(4):L295-301. PMID: 24951774; PMCID: PMC4137165.
      View in: PubMed, PubMed Central
    44. Castro M, King TS, Kunselman SJ, Cabana MD, Denlinger L, Holguin F, Kazani SD, Moore WC, Moy J, Sorkness CA, Avila P, Bacharier LB, Bleecker E, Boushey HA, Chmiel J, Fitzpatrick AM, Gentile D, Hundal M, Israel E, Kraft M, Krishnan JA, LaForce C, Lazarus SC, Lemanske R, Lugogo N, Martin RJ, Mauger DT, Naureckas E, Peters SP, Phipatanakul W, Que LG, Sheshadri A, Smith L, Solway J, Sullivan-Vedder L, Sumino K, Wechsler ME, Wenzel S, White SR, Sutherland ER. Effect of vitamin D3 on asthma treatment failures in adults with symptomatic asthma and lower vitamin D levels: the VIDA randomized clinical trial. JAMA. 2014 May; 311(20):2083-91. PMID: 24838406; PMCID: PMC4217655.
      View in: PubMed, PubMed Central
    45. Good JT, Rollins DR, Curran-Everett D, Lommatzsch SE, Carolan BJ, Stubenrauch PC, Martin RJ. An index to objectively score supraglottic abnormalities in refractory asthma: learning, validation, and significance. Chest. 2014 Mar 01; 145(3):486-91. PMID: 24202552; PMCID: PMC3941246.
      View in: PubMed, PubMed Central
    46. Good JT, Rollins DR, Curran-Everett D, Lommatzsch SE, Carolan BJ, Stubenrauch PC, Martin RJ. An Index to Objectively Score Supraglottic Abnormalities in Refractory Asthma. Chest. 2014 Mar; 145(3):486-491. PMID: 27845632.
      View in: PubMed
    47. Prakash YS, Martin RJ. Brain-derived neurotrophic factor in the airways. Pharmacol Ther. 2014 Jul; 143(1):74-86. PMID: 24560686; PMCID: PMC3990251.
      View in: PubMed, PubMed Central
    48. Martin RJ, Chisholm AM, Price D. The arch conference declaration. Helping to further the science of pragmatic research. Ann Am Thorac Soc. 2014 Feb; 11 Suppl 2:S83-4. PMID: 24559025.
      View in: PubMed
    49. Buxton SK, Charvet CL, Neveu C, Cabaret J, Cortet J, Peineau N, Abongwa M, Courtot E, Robertson AP, Martin RJ. Investigation of acetylcholine receptor diversity in a nematode parasite leads to characterization of tribendimidine- and derquantel-sensitive nAChRs. PLoS Pathog. 2014 Jan; 10(1):e1003870. PMID: 24497826.
      View in: PubMed
    50. Chung EH, Jia Y, Ohnishi H, Takeda K, Leung DY, Sutherland ER, Dakhama A, Martin RJ, Gelfand EW. Leukotriene B4 receptor 1 is differentially expressed on peripheral T cells of steroid-sensitive and -resistant asthmatics. Ann Allergy Asthma Immunol. 2014 Mar; 112(3):211-216.e1. PMID: 24428972; PMCID: PMC3951978.
      View in: PubMed, PubMed Central
    51. Martin RJ, Flores S, Kraft M. The lung microbiome. A new frontier in pulmonary medicine: introduction and perspective. Ann Am Thorac Soc. 2014 Jan; 11 Suppl 1:S1-2. PMID: 24437397.
      View in: PubMed
    52. Roche N, Reddel HK, Agusti A, Bateman ED, Krishnan JA, Martin RJ, Papi A, Postma D, Thomas M, Brusselle G, Israel E, Rand C, Chisholm A, Price D. Integrating real-life studies in the global therapeutic research framework. Lancet Respir Med. 2013 Dec; 1(10):e29-30. PMID: 24461762.
      View in: PubMed
    53. Goleva E, Jackson LP, Harris JK, Robertson CE, Sutherland ER, Hall CF, Good JT, Gelfand EW, Martin RJ, Leung DY. The effects of airway microbiome on corticosteroid responsiveness in asthma. Am J Respir Crit Care Med. 2013 Nov 15; 188(10):1193-201. PMID: 24024497; PMCID: PMC3863730.
      View in: PubMed, PubMed Central
    54. Britt RD, Faksh A, Vogel E, Martin RJ, Pabelick CM, Prakash YS. Perinatal factors in neonatal and pediatric lung diseases. Expert Rev Respir Med. 2013 Oct; 7(5):515-31. PMID: 24090092; PMCID: PMC4109979.
      View in: PubMed, PubMed Central
    55. Peters SP, Bleecker ER, Kunselman SJ, Icitovic N, Moore WC, Pascual R, Ameredes BT, Boushey HA, Calhoun WJ, Castro M, Cherniack RM, Craig T, Denlinger LC, Engle LL, Dimango EA, Israel E, Kraft M, Lazarus SC, Lemanske RF, Lugogo N, Martin RJ, Meyers DA, Ramsdell J, Sorkness CA, Sutherland ER, Wasserman SI, Walter MJ, Wechsler ME, Chinchilli VM, Szefler SJ. Predictors of response to tiotropium versus salmeterol in asthmatic adults. J Allergy Clin Immunol. 2013 Nov; 132(5):1068-1074.e1. PMID: 24084072; PMCID: PMC3826080.
      View in: PubMed, PubMed Central
    56. Colice G, Martin RJ, Israel E, Roche N, Barnes N, Burden A, Polos P, Dorinsky P, Hillyer EV, Lee AJ, Chisholm A, von Ziegenweidt J, Barion F, Price D. Asthma outcomes and costs of therapy with extrafine beclomethasone and fluticasone. J Allergy Clin Immunol. 2013 Jul; 132(1):45-54. PMID: 23591272.
      View in: PubMed
    57. Lommatzsch SE, Martin RJ, Good JT. Importance of fiberoptic bronchoscopy in identifying asthma phenotypes to direct personalized therapy. Curr Opin Pulm Med. 2013 Jan; 19(1):42-8. PMID: 23197289.
      View in: PubMed
    58. Wu Q, Case SR, Minor MN, Jiang D, Martin RJ, Bowler RP, Wang J, Hartney J, Karimpour-Fard A, Chu HW. A novel function of MUC18: amplification of lung inflammation during bacterial infection. Am J Pathol. 2013 Mar; 182(3):819-27. PMID: 23256918; PMCID: PMC3586690.
      View in: PubMed, PubMed Central
    59. Denlinger LC, Manthei DM, Seibold MA, Ahn K, Bleecker E, Boushey HA, Calhoun WJ, Castro M, Chinchili VM, Fahy JV, Hawkins GA, Icitovic N, Israel E, Jarjour NN, King T, Kraft M, Lazarus SC, Lehman E, Martin RJ, Meyers DA, Peters SP, Sheerar D, Shi L, Sutherland ER, Szefler SJ, Wechsler ME, Sorkness CA, Lemanske RF. P2X7-regulated protection from exacerbations and loss of control is independent of asthma maintenance therapy. Am J Respir Crit Care Med. 2013 Jan 01; 187(1):28-33. PMID: 23144325; PMCID: PMC3570642.
      View in: PubMed, PubMed Central
    60. Calhoun WJ, Ameredes BT, King TS, Icitovic N, Bleecker ER, Castro M, Cherniack RM, Chinchilli VM, Craig T, Denlinger L, DiMango EA, Engle LL, Fahy JV, Grant JA, Israel E, Jarjour N, Kazani SD, Kraft M, Kunselman SJ, Lazarus SC, Lemanske RF, Lugogo N, Martin RJ, Meyers DA, Moore WC, Pascual R, Peters SP, Ramsdell J, Sorkness CA, Sutherland ER, Szefler SJ, Wasserman SI, Walter MJ, Wechsler ME, Boushey HA. Comparison of physician-, biomarker-, and symptom-based strategies for adjustment of inhaled corticosteroid therapy in adults with asthma: the BASALT randomized controlled trial. JAMA. 2012 Sep 12; 308(10):987-97. PMID: 22968888; PMCID: PMC3697088.
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    61. Hartman WR, Smelter DF, Sathish V, Karass M, Kim S, Aravamudan B, Thompson MA, Amrani Y, Pandya HC, Martin RJ, Prakash YS, Pabelick CM. Oxygen dose responsiveness of human fetal airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2012 Oct 15; 303(8):L711-9. PMID: 22923637; PMCID: PMC3469631.
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    62. Alton EW, Boushey HA, Garn H, Green FH, Hodges M, Martin RJ, Murdoch RD, Renz H, Shrewsbury SB, Seguin R, Johnson G, Parry JD, Tepper J, Renzi P, Cavagnaro J, Ferrari N. Clinical expert panel on monitoring potential lung toxicity of inhaled oligonucleotides: consensus points and recommendations. Nucleic Acid Ther. 2012 Aug; 22(4):246-54. PMID: 22809313; PMCID: PMC3426204.
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    63. Thaikoottathil JV, Martin RJ, Di PY, Minor M, Case S, Zhang B, Zhang G, Huang H, Chu HW. SPLUNC1 deficiency enhances airway eosinophilic inflammation in mice. Am J Respir Cell Mol Biol. 2012 Aug; 47(2):253-60. PMID: 22499853; PMCID: PMC3423460.
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    64. Fischer A, Solomon JJ, du Bois RM, Deane KD, Olson AL, Fernandez-Perez ER, Huie TJ, Stevens AD, Gill MB, Rabinovitch AM, Lynch DA, Burns DA, Pineiro IS, Groshong SD, Duarte Achcar RD, Brown KK, Martin RJ, Swigris JJ. Lung disease with anti-CCP antibodies but not rheumatoid arthritis or connective tissue disease. Respir Med. 2012 Jul; 106(7):1040-7. PMID: 22503074; PMCID: PMC3753791.
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    65. Gould NS, Min E, Martin RJ, Day BJ. CFTR is the primary known apical glutathione transporter involved in cigarette smoke-induced adaptive responses in the lung. Free Radic Biol Med. 2012 Apr 01; 52(7):1201-6. PMID: 22266045; PMCID: PMC3920665.
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    66. Good JT, Rollins DR, Martin RJ. Macrolides in the treatment of asthma. Curr Opin Pulm Med. 2012 Jan; 18(1):76-84. PMID: 22112996.
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    67. Keith RC, Powers JL, Redente EF, Sergew A, Martin RJ, Gizinski A, Holers VM, Sakaguchi S, Riches DW. A novel model of rheumatoid arthritis-associated interstitial lung disease in SKG mice. Exp Lung Res. 2012 Mar; 38(2):55-66. PMID: 22185348.
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    68. Wu Q, Jiang D, Smith S, Thaikoottathil J, Martin RJ, Bowler RP, Chu HW. IL-13 dampens human airway epithelial innate immunity through induction of IL-1 receptor-associated kinase M. J Allergy Clin Immunol. 2012 Mar; 129(3):825-833.e2. PMID: 22154382; PMCID: PMC3348857.
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    69. Gould NS, Min E, Gauthier S, Martin RJ, Day BJ. Lung glutathione adaptive responses to cigarette smoke exposure. Respir Res. 2011 Oct 07; 12:133. PMID: 21982222; PMCID: PMC3215650.
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    70. Ali NK, Jafri A, Sopi RB, Prakash YS, Martin RJ, Zaidi SI. Role of arginase in impairing relaxation of lung parenchyma of hyperoxia-exposed neonatal rats. Neonatology. 2012; 101(2):106-15. PMID: 21952491; PMCID: PMC3223066.
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    71. Case SR, Martin RJ, Jiang D, Minor MN, Chu HW. MicroRNA-21 inhibits toll-like receptor 2 agonist-induced lung inflammation in mice. Exp Lung Res. 2011 Oct; 37(8):500-8. PMID: 21892915.
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    72. Good JT, Kolakowski CA, Groshong SD, Murphy JR, Martin RJ. Refractory asthma: importance of bronchoscopy to identify phenotypes and direct therapy. Chest. 2012 Mar; 141(3):599-606. PMID: 21835905.
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    73. Meuchel LW, Stewart A, Smelter DF, Abcejo AJ, Thompson MA, Zaidi SI, Martin RJ, Prakash YS. Neurokinin-neurotrophin interactions in airway smooth muscle. Am J Physiol Lung Cell Mol Physiol. 2011 Jul; 301(1):L91-8. PMID: 21515660; PMCID: PMC3129899.
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    74. Zhang W, Case S, Bowler RP, Martin RJ, Jiang D, Chu HW. Cigarette smoke modulates PGE(2) and host defence against Moraxella catarrhalis infection in human airway epithelial cells. Respirology. 2011 Apr; 16(3):508-16. PMID: 21199162.
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    75. Wu Q, Jiang D, Minor MN, Martin RJ, Chu HW. In vivo function of airway epithelial TLR2 in host defense against bacterial infection. Am J Physiol Lung Cell Mol Physiol. 2011 Apr; 300(4):L579-86. PMID: 21239529; PMCID: PMC3075102.
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    76. Simon GC, Martin RJ, Smith S, Thaikoottathil J, Bowler RP, Barenkamp SJ, Chu HW. Up-regulation of MUC18 in airway epithelial cells by IL-13: implications in bacterial adherence. Am J Respir Cell Mol Biol. 2011 May; 44(5):606-13. PMID: 21239604; PMCID: PMC3095981.
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    77. Huang YJ, Nelson CE, Brodie EL, Desantis TZ, Baek MS, Liu J, Woyke T, Allgaier M, Bristow J, Wiener-Kronish JP, Sutherland ER, King TS, Icitovic N, Martin RJ, Calhoun WJ, Castro M, Denlinger LC, Dimango E, Kraft M, Peters SP, Wasserman SI, Wechsler ME, Boushey HA, Lynch SV. Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma. J Allergy Clin Immunol. 2011 Feb; 127(2):372-381.e1-3. PMID: 21194740; PMCID: PMC3037020.
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    78. Chu HW, Gally F, Thaikoottathil J, Janssen-Heininger YM, Wu Q, Zhang G, Reisdorph N, Case S, Minor M, Smith S, Jiang D, Michels N, Simon G, Martin RJ. SPLUNC1 regulation in airway epithelial cells: role of Toll-like receptor 2 signaling. Respir Res. 2010 Nov 05; 11:155. PMID: 21054862; PMCID: PMC2992501.
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    79. Sutherland ER, King TS, Icitovic N, Ameredes BT, Bleecker E, Boushey HA, Calhoun WJ, Castro M, Cherniack RM, Chinchilli VM, Craig TJ, Denlinger L, DiMango EA, Fahy JV, Israel E, Jarjour N, Kraft M, Lazarus SC, Lemanske RF, Peters SP, Ramsdell J, Sorkness CA, Szefler SJ, Walter MJ, Wasserman SI, Wechsler ME, Chu HW, Martin RJ. A trial of clarithromycin for the treatment of suboptimally controlled asthma. J Allergy Clin Immunol. 2010 Oct; 126(4):747-53. PMID: 20920764; PMCID: PMC2950827.
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    80. Peters SP, Kunselman SJ, Icitovic N, Moore WC, Pascual R, Ameredes BT, Boushey HA, Calhoun WJ, Castro M, Cherniack RM, Craig T, Denlinger L, Engle LL, DiMango EA, Fahy JV, Israel E, Jarjour N, Kazani SD, Kraft M, Lazarus SC, Lemanske RF, Lugogo N, Martin RJ, Meyers DA, Ramsdell J, Sorkness CA, Sutherland ER, Szefler SJ, Wasserman SI, Walter MJ, Wechsler ME, Chinchilli VM, Bleecker ER. Tiotropium bromide step-up therapy for adults with uncontrolled asthma. N Engl J Med. 2010 Oct 28; 363(18):1715-26. PMID: 20979471.
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    81. Jobe AH, Martin RJ. 24/7 neonatal intensive care unit attending physician coverage: a clash of missions. Am J Respir Crit Care Med. 2010 Sep 15; 182(6):729-31. PMID: 20833828.
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    82. Price D, Martin RJ, Barnes N, Dorinsky P, Israel E, Roche N, Chisholm A, Hillyer EV, Kemp L, Lee AJ, von Ziegenweidt J, Colice G. Prescribing practices and asthma control with hydrofluoroalkane-beclomethasone and fluticasone: a real-world observational study. J Allergy Clin Immunol. 2010 Sep; 126(3):511-8.e1-10. PMID: 20692026.
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    83. Li LB, Leung DY, Martin RJ, Goleva E. Inhibition of histone deacetylase 2 expression by elevated glucocorticoid receptor beta in steroid-resistant asthma. Am J Respir Crit Care Med. 2010 Oct 01; 182(7):877-83. PMID: 20538962; PMCID: PMC2970859.
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    84. Rosenthal LA, Avila PC, Heymann PW, Martin RJ, Miller EK, Papadopoulos NG, Peebles RS, Gern JE. Viral respiratory tract infections and asthma: the course ahead. J Allergy Clin Immunol. 2010 Jun; 125(6):1212-7. PMID: 20513518; PMCID: PMC2880817.
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    85. Szefler SJ, Martin RJ. Lessons learned from variation in response to therapy in clinical trials. J Allergy Clin Immunol. 2010 Feb; 125(2):285-92; quiz 293-4. PMID: 20074785; PMCID: PMC2904979.
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    86. Rollins DR, Beuther DA, Martin RJ. Update on infection and antibiotics in asthma. Curr Allergy Asthma Rep. 2010 Jan; 10(1):67-73. PMID: 20425516.
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    87. Langmack EL, Martin RJ. Heterogeneity of response to asthma controller therapy: clinical implications. Curr Opin Pulm Med. 2010 Jan; 16(1):13-8. PMID: 19875959.
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    88. Trasande L, Newman N, Long L, Howe G, Kerwin BJ, Martin RJ, Gahagan SA, Weil WB. Translating knowledge about environmental health to practitioners: are we doing enough? Mt Sinai J Med. 2010 Jan-Feb; 77(1):114-23. PMID: 20101722.
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    89. Golski CA, Rome ES, Martin RJ, Frank SH, Worley S, Sun Z, Hibbs AM. Pediatric specialists' beliefs about gastroesophageal reflux disease in premature infants. Pediatrics. 2010 Jan; 125(1):96-104. PMID: 20008431; PMCID: PMC2805060.
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    90. Martin RJ. Small airways symposium. J Allergy Clin Immunol. 2009 Dec; 124(6 Suppl):S71. PMID: 19962038.
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    91. Wechsler ME, Kunselman SJ, Chinchilli VM, Bleecker E, Boushey HA, Calhoun WJ, Ameredes BT, Castro M, Craig TJ, Denlinger L, Fahy JV, Jarjour N, Kazani S, Kim S, Kraft M, Lazarus SC, Lemanske RF, Markezich A, Martin RJ, Permaul P, Peters SP, Ramsdell J, Sorkness CA, Sutherland ER, Szefler SJ, Walter MJ, Wasserman SI, Israel E. Effect of beta2-adrenergic receptor polymorphism on response to longacting beta2 agonist in asthma (LARGE trial): a genotype-stratified, randomised, placebo-controlled, crossover trial. Lancet. 2009 Nov 21; 374(9703):1754-64. PMID: 19932356; PMCID: PMC2914569.
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    92. Green RM, Gally F, Keeney JG, Alper S, Gao B, Han M, Martin RJ, Weinberger AR, Case SR, Minor MN, Chu HW. Impact of cigarette smoke exposure on innate immunity: a Caenorhabditis elegans model. PLoS One. 2009 Aug 31; 4(8):e6860. PMID: 19718433; PMCID: PMC2729919.
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    93. Ge XN, Chu HW, Minor MN, Case SR, Bosch DG, Martin RJ. Roflumilast increases Clara cell secretory protein in cigarette smoke-exposed mice. COPD. 2009 Jun; 6(3):185-91. PMID: 19811374.
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    94. Martin RJ, Kraft M, Rand Sutherland E. Thomas L. Petty Aspen Lung Conference: Asthma: Insights and Expectations. Introduction and perspective. Proc Am Thorac Soc. 2009 May 01; 6(3):247-8. PMID: 19387024.
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    95. Casale TB, Martin RJ. Clinical importance of identifying immunoglobulin E-mediated disease in patients with asthma. Clin Cornerstone. 2009; 9(3):20-9. PMID: 19781512.
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    96. Martin RJ. Exploring the distal lung: new direction in asthma. Isr Med Assoc J. 2008 Dec; 10(12):846-9. PMID: 19160939.
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    97. Goleva E, Hauk PJ, Hall CF, Liu AH, Riches DW, Martin RJ, Leung DY. Corticosteroid-resistant asthma is associated with classical antimicrobial activation of airway macrophages. J Allergy Clin Immunol. 2008 Sep; 122(3):550-9.e3. PMID: 18774390; PMCID: PMC3930345.
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    98. Kariya C, Chu HW, Huang J, Leitner H, Martin RJ, Day BJ. Mycoplasma pneumoniae infection and environmental tobacco smoke inhibit lung glutathione adaptive responses and increase oxidative stress. Infect Immun. 2008 Oct; 76(10):4455-62. PMID: 18644874; PMCID: PMC2546817.
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    99. Baqir M, Chen CZ, Martin RJ, Thaikoottathil J, Case SR, Minor MN, Bowler R, Chu HW. Cigarette smoke decreases MARCO expression in macrophages: implication in Mycoplasma pneumoniae infection. Respir Med. 2008 Nov; 102(11):1604-10. PMID: 18590957.
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    100. Sopi RB, Martin RJ, Haxhiu MA, Dreshaj IA, Yao Q, Jafri A, Zaidi SI. Role of brain-derived neurotrophic factor in hyperoxia-induced enhancement of contractility and impairment of relaxation in lung parenchyma. Am J Physiol Lung Cell Mol Physiol. 2008 Aug; 295(2):L348-55. PMID: 18515408; PMCID: PMC2519841.
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    101. Wu Q, Martin RJ, Lafasto S, Efaw BJ, Rino JG, Harbeck RJ, Chu HW. Toll-like receptor 2 down-regulation in established mouse allergic lungs contributes to decreased mycoplasma clearance. Am J Respir Crit Care Med. 2008 Apr 01; 177(7):720-9. PMID: 18202345.
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    102. Sutherland ER, Martin RJ. Asthma and atypical bacterial infection. Chest. 2007 Dec; 132(6):1962-6. PMID: 18079229.
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    103. Goleva E, Hauk PJ, Boguniewicz J, Martin RJ, Leung DY. Airway remodeling and lack of bronchodilator response in steroid-resistant asthma. J Allergy Clin Immunol. 2007 Nov; 120(5):1065-72. PMID: 17900681; PMCID: PMC2697657.
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    104. Chu HW, Thaikoottathil J, Rino JG, Zhang G, Wu Q, Moss T, Refaeli Y, Bowler R, Wenzel SE, Chen Z, Zdunek J, Breed R, Young R, Allaire E, Martin RJ. Function and regulation of SPLUNC1 protein in Mycoplasma infection and allergic inflammation. J Immunol. 2007 Sep 15; 179(6):3995-4002. PMID: 17785838.
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    105. Sopi RB, Haxhiu MA, Martin RJ, Dreshaj IA, Kamath S, Zaidi SI. Disruption of NO-cGMP signaling by neonatal hyperoxia impairs relaxation of lung parenchyma. Am J Physiol Lung Cell Mol Physiol. 2007 Oct; 293(4):L1029-36. PMID: 17660329.
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    106. Lazarus SC, Chinchilli VM, Rollings NJ, Boushey HA, Cherniack R, Craig TJ, Deykin A, DiMango E, Fish JE, Ford JG, Israel E, Kiley J, Kraft M, Lemanske RF, Leone FT, Martin RJ, Pesola GR, Peters SP, Sorkness CA, Szefler SJ, Wechsler ME, Fahy JV. Smoking affects response to inhaled corticosteroids or leukotriene receptor antagonists in asthma. Am J Respir Crit Care Med. 2007 Apr 15; 175(8):783-90. PMID: 17204725; PMCID: PMC1899291.
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    107. Martin RJ, Szefler SJ, King TS, Kraft M, Boushey HA, Chinchilli VM, Craig TJ, Dimango EA, Deykin A, Fahy JV, Israel E, Lazarus SC, Lemanske RF, Leone FT, Pesola GR, Peters SP, Sorkness CA, Szwejbka LA, Wechsler ME. The Predicting Response to Inhaled Corticosteroid Efficacy (PRICE) trial. J Allergy Clin Immunol. 2007 Jan; 119(1):73-80. PMID: 17208587; PMCID: PMC2872157.
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    108. Smith PG, Dreshaj A, Chaudhuri S, Onder BM, Mhanna MJ, Martin RJ. Hyperoxic conditions inhibit airway smooth muscle myosin phosphatase in rat pups. Am J Physiol Lung Cell Mol Physiol. 2007 Jan; 292(1):L68-73. PMID: 17215435.
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    109. Wu Q, Martin RJ, Rino JG, Jeyaseelan S, Breed R, Chu HW. A deficient TLR2 signaling promotes airway mucin production in Mycoplasma pneumoniae-infected allergic mice. Am J Physiol Lung Cell Mol Physiol. 2007 May; 292(5):L1064-72. PMID: 17194718.
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    110. Wu Q, Martin RJ, Rino JG, Breed R, Torres RM, Chu HW. IL-23-dependent IL-17 production is essential in neutrophil recruitment and activity in mouse lung defense against respiratory Mycoplasma pneumoniae infection. Microbes Infect. 2007 Jan; 9(1):78-86. PMID: 17198762; PMCID: PMC1832075.
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    111. Deykin A, Wechsler ME, Boushey HA, Chinchilli VM, Kunselman SJ, Craig TJ, DiMango E, Fahy JV, Kraft M, Leone F, Lazarus SC, Lemanske RF, Martin RJ, Pesola GR, Peters SP, Sorkness CA, Szefler SJ, Israel E. Combination therapy with a long-acting beta-agonist and a leukotriene antagonist in moderate asthma. Am J Respir Crit Care Med. 2007 Feb 01; 175(3):228-34. PMID: 16973987; PMCID: PMC1899264.
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    112. Iben SC, Haxhiu MA, Farver CF, Miller MJ, Martin RJ. Short-term mechanical ventilation increases airway reactivity in rat pups. Pediatr Res. 2006 Aug; 60(2):136-40. PMID: 16864692.
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    113. Chu HW, Breed R, Rino JG, Harbeck RJ, Sills MR, Martin RJ. Repeated respiratory Mycoplasma pneumoniae infections in mice: effect of host genetic background. Microbes Infect. 2006 Jun; 8(7):1764-72. PMID: 16713727.
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    114. Beuther DA, Martin RJ. Efficacy of a heat exchanger mask in cold exercise-induced asthma. Chest. 2006 May; 129(5):1188-93. PMID: 16685008.
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    115. Johnston SL, Blasi F, Black PN, Martin RJ, Farrell DJ, Nieman RB. The effect of telithromycin in acute exacerbations of asthma. N Engl J Med. 2006 Apr 13; 354(15):1589-600. PMID: 16611950.
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    116. Martin RJ, Wexler RB, Day BJ, Harbeck RJ, Pinkerton KE, Chu HW. Interaction between cigarette smoke and mycoplasma infection: a murine model. COPD. 2006 Mar; 3(1):3-8. PMID: 17175659.
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    117. Martin RJ. Infections and asthma. Clin Chest Med. 2006 Mar; 27(1):87-98, vi. PMID: 16543054.
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    118. Goleva E, Li LB, Eves PT, Strand MJ, Martin RJ, Leung DY. Increased glucocorticoid receptor beta alters steroid response in glucocorticoid-insensitive asthma. Am J Respir Crit Care Med. 2006 Mar 15; 173(6):607-16. PMID: 16387802; PMCID: PMC2662945.
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    119. Wechsler ME, Lehman E, Lazarus SC, Lemanske RF, Boushey HA, Deykin A, Fahy JV, Sorkness CA, Chinchilli VM, Craig TJ, DiMango E, Kraft M, Leone F, Martin RJ, Peters SP, Szefler SJ, Liu W, Israel E. beta-Adrenergic receptor polymorphisms and response to salmeterol. Am J Respir Crit Care Med. 2006 Mar 01; 173(5):519-26. PMID: 16322642; PMCID: PMC2662935.
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    120. Martin RJ, Walsh MC, Carlo WA. Reevaluating neonatal resuscitation with 100% oxygen. Am J Respir Crit Care Med. 2005 Dec 01; 172(11):1360-1. PMID: 16301299.
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    121. Whelan GJ, Blumer JL, Martin RJ, Szefler SJ. Fluticasone propionate plasma concentration and systemic effect: effect of delivery device and duration of administration. J Allergy Clin Immunol. 2005 Sep; 116(3):525-30. PMID: 16159619.
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    122. Johnston SL, Martin RJ. Chlamydophila pneumoniae and Mycoplasma pneumoniae: a role in asthma pathogenesis? Am J Respir Crit Care Med. 2005 Nov 01; 172(9):1078-89. PMID: 15961690.
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    123. Chu HW, Jeyaseelan S, Rino JG, Voelker DR, Wexler RB, Campbell K, Harbeck RJ, Martin RJ. TLR2 signaling is critical for Mycoplasma pneumoniae-induced airway mucin expression. J Immunol. 2005 May 01; 174(9):5713-9. PMID: 15843573.
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    124. Boushey HA, Sorkness CA, King TS, Sullivan SD, Fahy JV, Lazarus SC, Chinchilli VM, Craig TJ, Dimango EA, Deykin A, Fagan JK, Fish JE, Ford JG, Kraft M, Lemanske RF, Leone FT, Martin RJ, Mauger EA, Pesola GR, Peters SP, Rollings NJ, Szefler SJ, Wechsler ME, Israel E. Daily versus as-needed corticosteroids for mild persistent asthma. N Engl J Med. 2005 Apr 14; 352(15):1519-28. PMID: 15829533.
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    125. Yao Q, Haxhiu MA, Zaidi SI, Liu S, Jafri A, Martin RJ. Hyperoxia enhances brain-derived neurotrophic factor and tyrosine kinase B receptor expression in peribronchial smooth muscle of neonatal rats. Am J Physiol Lung Cell Mol Physiol. 2005 Aug; 289(2):L307-14. PMID: 15821016.
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    126. Deykin A, Lazarus SC, Fahy JV, Wechsler ME, Boushey HA, Chinchilli VM, Craig TJ, Dimango E, Kraft M, Leone F, Lemanske RF, Martin RJ, Pesola GR, Peters SP, Sorkness CA, Szefler SJ, Israel E. Sputum eosinophil counts predict asthma control after discontinuation of inhaled corticosteroids. J Allergy Clin Immunol. 2005 Apr; 115(4):720-7. PMID: 15805990.
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    127. Chu HW, Rino JG, Wexler RB, Campbell K, Harbeck RJ, Martin RJ. Mycoplasma pneumoniae infection increases airway collagen deposition in a murine model of allergic airway inflammation. Am J Physiol Lung Cell Mol Physiol. 2005 Jul; 289(1):L125-33. PMID: 15778249.
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    128. Sutherland ER, Martin RJ. Targeting the distal lung in asthma: do inhaled corticosteroids treat all areas of inflammation? Treat Respir Med. 2005; 4(4):223-9. PMID: 16086596.
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    129. Buyantseva LV, Chinchilli VM, Tulchinsky M, Bascom R, Martin RJ. Alternatives for measuring endogenous adrenocortical activity in asthmatics treated with inhaled corticosteroids. Endocr Res. 2005; 31(4):245-58. PMID: 16433245.
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    130. Israel E, Chinchilli VM, Ford JG, Boushey HA, Cherniack R, Craig TJ, Deykin A, Fagan JK, Fahy JV, Fish J, Kraft M, Kunselman SJ, Lazarus SC, Lemanske RF, Liggett SB, Martin RJ, Mitra N, Peters SP, Silverman E, Sorkness CA, Szefler SJ, Wechsler ME, Weiss ST, Drazen JM. Use of regularly scheduled albuterol treatment in asthma: genotype-stratified, randomised, placebo-controlled cross-over trial. Lancet. 2004 Oct 23-29; 364(9444):1505-12. PMID: 15500895.
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    131. Covar RA, Spahn JD, Martin RJ, Silkoff PE, Sundstrom DA, Murphy J, Szefler SJ. Safety and application of induced sputum analysis in childhood asthma. J Allergy Clin Immunol. 2004 Sep; 114(3):575-82. PMID: 15356559.
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    132. Sutherland ER, Martin RJ, Bowler RP, Zhang Y, Rex MD, Kraft M. Physiologic correlates of distal lung inflammation in asthma. J Allergy Clin Immunol. 2004 Jun; 113(6):1046-50. PMID: 15208583.
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    133. Chu HW, Campbell JA, Rino JG, Harbeck RJ, Martin RJ. Inhaled fluticasone propionate reduces concentration of Mycoplasma pneumoniae, inflammation, and bronchial hyperresponsiveness in lungs of mice. J Infect Dis. 2004 Mar 15; 189(6):1119-27. PMID: 14999617.
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    134. Grischkan J, Storfer-Isser A, Rosen CL, Larkin EK, Kirchner HL, South A, Wilson-Costello DC, Martin RJ, Redline S. Variation in childhood asthma among former preterm infants. J Pediatr. 2004 Mar; 144(3):321-6. PMID: 15001935.
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    135. Beuther DA, Martin RJ. Antibiotics in asthma. Curr Allergy Asthma Rep. 2004 Mar; 4(2):132-8. PMID: 14769262.
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    136. Sutherland ER, Brandorff JM, Martin RJ. Atypical bacterial pneumonia and asthma risk. J Asthma. 2004; 41(8):863-8. PMID: 15641636.
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    137. Martin RJ. Considering therapeutic options in the real world. J Allergy Clin Immunol. 2003 Nov; 112(5 Suppl):S112-5. PMID: 14586396.
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    138. Sutherland ER, Martin RJ. Airway inflammation in chronic obstructive pulmonary disease: comparisons with asthma. J Allergy Clin Immunol. 2003 Nov; 112(5):819-27; quiz 828. PMID: 14610463.
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    139. Sutherland ER, Ellison MC, Kraft M, Martin RJ. Elevated serum melatonin is associated with the nocturnal worsening of asthma. J Allergy Clin Immunol. 2003 Sep; 112(3):513-7. PMID: 13679809.
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    140. Sutherland ER, Ellison MC, Kraft M, Martin RJ. Altered pituitary-adrenal interaction in nocturnal asthma. J Allergy Clin Immunol. 2003 Jul; 112(1):52-7. PMID: 12847479.
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    141. Kraft M, Martin RJ, Lazarus SC, Fahy JV, Boushey HA, Lemanske RF, Szefler SJ. Airway tissue mast cells in persistent asthma: predictor of treatment failure when patients discontinue inhaled corticosteroids. Chest. 2003 Jul; 124(1):42-50. PMID: 12853500.
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    142. Covar RA, Szefler SJ, Martin RJ, Sundstrom DA, Silkoff PE, Murphy J, Young DA, Spahn JD. Relations between exhaled nitric oxide and measures of disease activity among children with mild-to-moderate asthma. J Pediatr. 2003 May; 142(5):469-75. PMID: 12756375.
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    143. Dakhama A, Kraft M, Martin RJ, Gelfand EW. Induction of regulated upon activation, normal T cells expressed and secreted (RANTES) and transforming growth factor-beta 1 in airway epithelial cells by Mycoplasma pneumoniae. Am J Respir Cell Mol Biol. 2003 Sep; 29(3 Pt 1):344-51. PMID: 12714377.
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    144. Sutherland ER, Kraft M, Rex MD, Ellison MC, Martin RJ. Hypothalamic-pituitary-adrenal axis dysfunction during sleep in nocturnal asthma. Chest. 2003 Mar; 123(3 Suppl):405S. PMID: 12629004.
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    145. Martin RJ, Kraft M. Introduction: asthma in the new millennium. Chest. 2003 Mar; 123(3 Suppl):339S. PMID: 12628968.
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    146. Chu HW, Honour JM, Rawlinson CA, Harbeck RJ, Martin RJ. Effects of respiratory Mycoplasma pneumoniae infection on allergen-induced bronchial hyperresponsiveness and lung inflammation in mice. Infect Immun. 2003 Mar; 71(3):1520-6. PMID: 12595471; PMCID: PMC148884.
      View in: PubMed, PubMed Central
    147. Chu HW, Honour JM, Rawlinson CA, Harbeck RJ, Martin RJ. Hygiene hypothesis of asthma: a murine asthma model with Mycoplasma pneumoniae infection. Chest. 2003 Mar; 123(3 Suppl):390S. PMID: 12628998.
      View in: PubMed
    148. Chu HW, Campbell JA, Harbeck RJ, Martin RJ. Effects of inhaled fluticasone on bronchial hyperresponsiveness and airway inflammation in Mycoplasma pneumoniae-infected mice. Chest. 2003 Mar; 123(3 Suppl):427S. PMID: 12629016.
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    149. Pham DN, Chu HW, Martin RJ, Kraft M. Increased matrix metalloproteinase-9 with elastolysis in nocturnal asthma. Ann Allergy Asthma Immunol. 2003 Jan; 90(1):72-8. PMID: 12546341.
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    150. Steinhorn R, Martin RJ. Nitric oxide and the developing airway. Am J Physiol Lung Cell Mol Physiol. 2002 Dec; 283(6):L1190-1. PMID: 12424145.
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    151. Sutherland ER, Martin RJ, Ellison MC, Kraft M. Immunomodulatory effects of melatonin in asthma. Am J Respir Crit Care Med. 2002 Oct 15; 166(8):1055-61. PMID: 12379548.
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    152. Sutherland ER, Martin RJ. Distal lung inflammation in asthma. Ann Allergy Asthma Immunol. 2002 Aug; 89(2):119-24; quiz 124-5, 211. PMID: 12197566.
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    153. Vianna EO, Boaventura LC, Terra-Filho J, Nakama GY, Martinez JA, Martin RJ. Morning-to-evening variation in exercise-induced bronchospasm. J Allergy Clin Immunol. 2002 Aug; 110(2):236-40. PMID: 12170263.
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    154. Kraft M, Cassell GH, Pak J, Martin RJ. Mycoplasma pneumoniae and Chlamydia pneumoniae in asthma: effect of clarithromycin. Chest. 2002 Jun; 121(6):1782-8. PMID: 12065339.
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    155. Martin RJ, Szefler SJ, Chinchilli VM, Kraft M, Dolovich M, Boushey HA, Cherniack RM, Craig TJ, Drazen JM, Fagan JK, Fahy JV, Fish JE, Ford JG, Israel E, Kunselman SJ, Lazarus SC, Lemanske RF, Peters SP, Sorkness CA. Systemic effect comparisons of six inhaled corticosteroid preparations. Am J Respir Crit Care Med. 2002 May 15; 165(10):1377-83. PMID: 12016099.
      View in: PubMed
    156. Szefler SJ, Martin RJ, King TS, Boushey HA, Cherniack RM, Chinchilli VM, Craig TJ, Dolovich M, Drazen JM, Fagan JK, Fahy JV, Fish JE, Ford JG, Israel E, Kiley J, Kraft M, Lazarus SC, Lemanske RF, Mauger E, Peters SP, Sorkness CA. Significant variability in response to inhaled corticosteroids for persistent asthma. J Allergy Clin Immunol. 2002 Mar; 109(3):410-8. PMID: 11897984.
      View in: PubMed
    157. Martin RJ. Therapeutic significance of distal airway inflammation in asthma. J Allergy Clin Immunol. 2002 Feb; 109(2 Suppl):S447-60. PMID: 11842317.
      View in: PubMed
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