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David C Thompson

TitleAssociate Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOP-Administration
Phone303/724-2888

    Collapse Research 
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    R01HL047101     (THOMPSON, DAVID C)Aug 1, 1991 - Jul 31, 1997
    NIH/NHLBI
    LOCAL REFLEXES IN THE AIRWAYS
    Role: Principal Investigator

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Pantouris G, Dioletis E, Chen Y, Thompson DC, Vasiliou V, Lolis EJ. Expression, purification and crystallization of the novel Xenopus tropicalis ALDH16B1, a homologue of human ALDH16A1. Chem Biol Interact. 2019 May 01; 304:168-172. PMID: 30894314.
      View in: PubMed
    2. Charkoftaki G, Thompson DC, Golla JP, Garcia-Milian R, Lam TT, Engel J, Vasiliou V. Integrated multi-omics approach reveals a role of ALDH1A1 in lipid metabolism in human colon cancer cells. Chem Biol Interact. 2019 May 01; 304:88-96. PMID: 30851239.
      View in: PubMed
    3. Chen Y, Golla S, Garcia-Milian R, Thompson DC, Gonzalez FJ, Vasiliou V. Hepatic metabolic adaptation in a murine model of glutathione deficiency. Chem Biol Interact. 2019 Apr 25; 303:1-6. PMID: 30794799.
      View in: PubMed
    4. Charkoftaki G, Wang Y, McAndrews M, Bruford EA, Thompson DC, Vasiliou V, Nebert DW. Update on the human and mouse lipocalin (LCN) gene family, including evidence the mouse Mup cluster is result of an "evolutionary bloom". Hum Genomics. 2019 02 19; 13(1):11. PMID: 30782214.
      View in: PubMed
    5. Siegel D, Baca SM, Thompson DC, Huntsman MM, Mower MM, Ross D. The effect of anodal/cathodal biphasic electrical stimulation on insulin release. J Cell Physiol. 2019 Feb 11. PMID: 30746686.
      View in: PubMed
    6. Perkins AN, Inayat-Hussain SH, Deziel NC, Johnson CH, Ferguson SS, Garcia-Milian R, Thompson DC, Vasiliou V. Evaluation of potential carcinogenicity of organic chemicals in synthetic turf crumb rubber. Environ Res. 2019 Feb; 169:163-172. PMID: 30458352.
      View in: PubMed
    7. Mineur YS, Cahuzac EL, Mose TN, Bentham MP, Plantenga ME, Thompson DC, Picciotto MR. Interaction between noradrenergic and cholinergic signaling in amygdala regulates anxiety- and depression-related behaviors in mice. Neuropsychopharmacology. 2018 09; 43(10):2118-2125. PMID: 29472646.
      View in: PubMed
    8. Chen Y, Han M, Matsumoto A, Wang Y, Thompson DC, Vasiliou V. Glutathione and Transsulfuration in Alcohol-Associated Tissue Injury and Carcinogenesis. Adv Exp Med Biol. 2018; 1032:37-53. PMID: 30362089.
      View in: PubMed
    9. Marshall S, Chen Y, Singh S, Berrios-Carcamo P, Heit C, Apostolopoulos N, Golla JP, Thompson DC, Vasiliou V. Engineered Animal Models Designed for Investigating Ethanol Metabolism, Toxicity and Cancer. Adv Exp Med Biol. 2018; 1032:203-221. PMID: 30362100.
      View in: PubMed
    10. Charkoftaki G, Jester JV, Thompson DC, Vasiliou V. Nitrogen mustard-induced corneal injury involves the sphingomyelin-ceramide pathway. Ocul Surf. 2018 Jan; 16(1):154-162. PMID: 29129753.
      View in: PubMed
    11. Matsumoto A, Arcaroli J, Chen Y, Gasparetto M, Neumeister V, Thompson DC, Singh S, Smith C, Messersmith W, Vasiliou V. Aldehyde dehydrogenase 1B1: a novel immunohistological marker for colorectal cancer. Br J Cancer. 2017 Nov 07; 117(10):1537-1543. PMID: 28881356.
      View in: PubMed
    12. Fait BW, Thompson DC, Mose TN, Jatlow P, Jordt SE, Picciotto MR, Mineur YS. Menthol disrupts nicotine's psychostimulant properties in an age and sex-dependent manner in C57BL/6J mice. Behav Brain Res. 2017 09 15; 334:72-77. PMID: 28743602.
      View in: PubMed
    13. Charkoftaki G, Chen Y, Han M, Sandoval M, Yu X, Zhao H, Orlicky DJ, Thompson DC, Vasiliou V. Transcriptomic analysis and plasma metabolomics in Aldh16a1-null mice reveals a potential role of ALDH16A1 in renal function. Chem Biol Interact. 2017 Oct 01; 276:15-22. PMID: 28254523.
      View in: PubMed
    14. Li S, Zhao J, Huang R, Steiner T, Bourner M, Mitchell M, Thompson DC, Zhao B, Xia M. Development and Application of Human Renal Proximal Tubule Epithelial Cells for Assessment of Compound Toxicity. Curr Chem Genom Transl Med. 2017; 11:19-30. PMID: 28401035.
      View in: PubMed
    15. Chen Y, Jester JV, Anderson DM, Marchitti SA, Schey KL, Thompson DC, Vasiliou V. Corneal haze phenotype in Aldh3a1-null mice: In vivo confocal microscopy and tissue imaging mass spectrometry. Chem Biol Interact. 2017 Oct 01; 276:9-14. PMID: 28038895.
      View in: PubMed
    16. Heit C, Marshall S, Singh S, Yu X, Charkoftaki G, Zhao H, Orlicky DJ, Fritz KS, Thompson DC, Vasiliou V. Catalase deletion promotes prediabetic phenotype in mice. Free Radic Biol Med. 2017 02; 103:48-56. PMID: 27939935.
      View in: PubMed
    17. Matsumoto A, Thompson DC, Chen Y, Kitagawa K, Vasiliou V. Roles of defective ALDH2 polymorphism on liver protection and cancer development. Environ Health Prev Med. 2016 Nov; 21(6):395-402. PMID: 27714678.
      View in: PubMed
    18. Heit C, Eriksson P, Thompson DC, Charkoftaki G, Fritz KS, Vasiliou V. Quantification of Neural Ethanol and Acetaldehyde Using Headspace GC-MS. Alcohol Clin Exp Res. 2016 09; 40(9):1825-31. PMID: 27501276.
      View in: PubMed
    19. Chen Y, Singh S, Matsumoto A, Manna SK, Abdelmegeed MA, Golla S, Murphy RC, Dong H, Song BJ, Gonzalez FJ, Thompson DC, Vasiliou V. Chronic Glutathione Depletion Confers Protection against Alcohol-induced Steatosis: Implication for Redox Activation of AMP-activated Protein Kinase Pathway. Sci Rep. 2016 07 12; 6:29743. PMID: 27403993.
      View in: PubMed
    20. Nebert DW, Dong H, Bruford EA, Thompson DC, Joenje H, Vasiliou V. Letter to the editor for "Update of the human and mouse Fanconi anemia genes". Hum Genomics. 2016 07 04; 10(1):25. PMID: 27377885.
      View in: PubMed
    21. Qiu X, Zhang Y, Liu T, Shen H, Xiao Y, Bourner MJ, Pratt JR, Thompson DC, Marathe P, Humphreys WG, Lai Y. Disruption of BSEP Function in HepaRG Cells Alters Bile Acid Disposition and Is a Susceptive Factor to Drug-Induced Cholestatic Injury. Mol Pharm. 2016 Apr 04; 13(4):1206-16. PMID: 26910619.
      View in: PubMed
    22. Koppaka V, Chen Y, Mehta G, Orlicky DJ, Thompson DC, Jester JV, Vasiliou V. ALDH3A1 Plays a Functional Role in Maintenance of Corneal Epithelial Homeostasis. PLoS One. 2016; 11(1):e0146433. PMID: 26751691.
      View in: PubMed
    23. Singh S, Arcaroli JJ, Orlicky DJ, Chen Y, Messersmith WA, Bagby S, Purkey A, Quackenbush KS, Thompson DC, Vasiliou V. Aldehyde Dehydrogenase 1B1 as a Modulator of Pancreatic Adenocarcinoma. Pancreas. 2016 Jan; 45(1):117-22. PMID: 26566217.
      View in: PubMed
    24. Dong H, Nebert DW, Bruford EA, Thompson DC, Joenje H, Vasiliou V. Update of the human and mouse Fanconi anemia genes. Hum Genomics. 2015 Nov 24; 9:32. PMID: 26596371.
      View in: PubMed
    25. Jackson BC, Thompson DC, Charkoftaki G, Vasiliou V. Dead enzymes in the aldehyde dehydrogenase gene family: role in drug metabolism and toxicology. Expert Opin Drug Metab Toxicol. 2015; 11(12):1839-47. PMID: 26558415.
      View in: PubMed
    26. Singh S, Chen Y, Matsumoto A, Orlicky DJ, Dong H, Thompson DC, Vasiliou V. ALDH1B1 links alcohol consumption and diabetes. Biochem Biophys Res Commun. 2015 Aug 07; 463(4):768-773. PMID: 26086111.
      View in: PubMed
    27. Singh S, Arcaroli J, Chen Y, Thompson DC, Messersmith W, Jimeno A, Vasiliou V. ALDH1B1 Is Crucial for Colon Tumorigenesis by Modulating Wnt/ß-Catenin, Notch and PI3K/Akt Signaling Pathways. PLoS One. 2015; 10(5):e0121648. PMID: 25950950.
      View in: PubMed
    28. Bentzien J, Bharadwaj R, Thompson DC. Crowdsourcing in pharma: a strategic framework. Drug Discov Today. 2015 Jul; 20(7):874-83. PMID: 25637169.
      View in: PubMed
    29. Heit C, Dong H, Chen Y, Shah YM, Thompson DC, Vasiliou V. Transgenic mouse models for alcohol metabolism, toxicity, and cancer. Adv Exp Med Biol. 2015; 815:375-87. PMID: 25427919.
      View in: PubMed
    30. Jackson BC, Reigan P, Miller B, Thompson DC, Vasiliou V. Human ALDH1B1 polymorphisms may affect the metabolism of acetaldehyde and all-trans retinaldehyde--in vitro studies and computational modeling. Pharm Res. 2015 May; 32(5):1648-62. PMID: 25413692.
      View in: PubMed
    31. Sampson KE, Brinker A, Pratt J, Venkatraman N, Xiao Y, Blasberg J, Steiner T, Bourner M, Thompson DC. Zinc finger nuclease-mediated gene knockout results in loss of transport activity for P-glycoprotein, BCRP, and MRP2 in Caco-2 cells. Drug Metab Dispos. 2015 Feb; 43(2):199-207. PMID: 25388687.
      View in: PubMed
    32. Monte AA, Brocker C, Nebert DW, Gonzalez FJ, Thompson DC, Vasiliou V. Improved drug therapy: triangulating phenomics with genomics and metabolomics. Hum Genomics. 2014 Sep 01; 8:16. PMID: 25181945.
      View in: PubMed
    33. Paul BT, Bruce IC, Bosnyak DJ, Thompson DC, Roberts LE. Modulation of electrocortical brain activity by attention in individuals with and without tinnitus. Neural Plast. 2014; 2014:127824. PMID: 25024849.
      View in: PubMed
    34. Jang JH, Bruse S, Liu Y, Duffy V, Zhang C, Oyamada N, Randell S, Matsumoto A, Thompson DC, Lin Y, Vasiliou V, Tesfaigzi Y, Nyunoya T. Aldehyde dehydrogenase 3A1 protects airway epithelial cells from cigarette smoke-induced DNA damage and cytotoxicity. Free Radic Biol Med. 2014 Mar; 68:80-6. PMID: 24316006.
      View in: PubMed
    35. Heit C, Jackson BC, McAndrews M, Wright MW, Thompson DC, Silverman GA, Nebert DW, Vasiliou V. Update of the human and mouse SERPIN gene superfamily. Hum Genomics. 2013 Oct 30; 7:22. PMID: 24172014.
      View in: PubMed
    36. Vasiliou V, Sandoval M, Backos DS, Jackson BC, Chen Y, Reigan P, Lanaspa MA, Johnson RJ, Koppaka V, Thompson DC. ALDH16A1 is a novel non-catalytic enzyme that may be involved in the etiology of gout via protein-protein interactions with HPRT1. Chem Biol Interact. 2013 Feb 25; 202(1-3):22-31. PMID: 23348497.
      View in: PubMed
    37. Bentzien J, Muegge I, Hamner B, Thompson DC. Crowd computing: using competitive dynamics to develop and refine highly predictive models. Drug Discov Today. 2013 May; 18(9-10):472-8. PMID: 23337388.
      View in: PubMed
    38. Heit C, Dong H, Chen Y, Thompson DC, Deitrich RA, Vasiliou VK. The role of CYP2E1 in alcohol metabolism and sensitivity in the central nervous system. Subcell Biochem. 2013; 67:235-47. PMID: 23400924.
      View in: PubMed
    39. Jackson BC, Holmes RS, Backos DS, Reigan P, Thompson DC, Vasiliou V. Comparative genomics, molecular evolution and computational modeling of ALDH1B1 and ALDH2. Chem Biol Interact. 2013 Feb 25; 202(1-3):11-21. PMID: 23247008.
      View in: PubMed
    40. Singh S, Brocker C, Koppaka V, Chen Y, Jackson BC, Matsumoto A, Thompson DC, Vasiliou V. Aldehyde dehydrogenases in cellular responses to oxidative/electrophilic stress. Free Radic Biol Med. 2013 Mar; 56:89-101. PMID: 23195683.
      View in: PubMed
    41. Vasiliou V, Thompson DC, Smith C, Fujita M, Chen Y. Aldehyde dehydrogenases: from eye crystallins to metabolic disease and cancer stem cells. Chem Biol Interact. 2013 Feb 25; 202(1-3):2-10. PMID: 23159885.
      View in: PubMed
    42. Thompson DC, Nuffer W, Brown K. Characteristics valued by the pharmacy practice community when hiring a recently graduated pharmacist. Am J Pharm Educ. 2012 Nov 12; 76(9):170. PMID: 23193334.
      View in: PubMed
    43. Chen Y, Thompson DC, Koppaka V, Jester JV, Vasiliou V. Ocular aldehyde dehydrogenases: protection against ultraviolet damage and maintenance of transparency for vision. Prog Retin Eye Res. 2013 Mar; 33:28-39. PMID: 23098688.
      View in: PubMed
    44. Luo Y, Dallaglio K, Chen Y, Robinson WA, Robinson SE, McCarter MD, Wang J, Gonzalez R, Thompson DC, Norris DA, Roop DR, Vasiliou V, Fujita M. ALDH1A isozymes are markers of human melanoma stem cells and potential therapeutic targets. Stem Cells. 2012 Oct; 30(10):2100-13. PMID: 22887839.
      View in: PubMed
    45. Brocker C, Thompson DC, Vasiliou V. The role of hyperosmotic stress in inflammation and disease. Biomol Concepts. 2012 Aug; 3(4):345-364. PMID: 22977648.
      View in: PubMed
    46. Roberts LE, Bosnyak DJ, Thompson DC. Neural plasticity expressed in central auditory structures with and without tinnitus. Front Syst Neurosci. 2012; 6:40. PMID: 22654738.
      View in: PubMed
    47. Pratt J, Venkatraman N, Brinker A, Xiao Y, Blasberg J, Thompson DC, Bourner M. Use of zinc finger nuclease technology to knock out efflux transporters in C2BBe1 cells. Curr Protoc Toxicol. 2012 May; Chapter 23:Unit 23.2.. PMID: 22549270.
      View in: PubMed
    48. Koppaka V, Thompson DC, Chen Y, Ellermann M, Nicolaou KC, Juvonen RO, Petersen D, Deitrich RA, Hurley TD, Vasiliou V. Aldehyde dehydrogenase inhibitors: a comprehensive review of the pharmacology, mechanism of action, substrate specificity, and clinical application. Pharmacol Rev. 2012 Jul; 64(3):520-39. PMID: 22544865.
      View in: PubMed
    49. Black W, Chen Y, Matsumoto A, Thompson DC, Lassen N, Pappa A, Vasiliou V. Molecular mechanisms of ALDH3A1-mediated cellular protection against 4-hydroxy-2-nonenal. Free Radic Biol Med. 2012 May 01; 52(9):1937-44. PMID: 22406320.
      View in: PubMed
    50. Gasparetto M, Sekulovic S, Brocker C, Tang P, Zakaryan A, Xiang P, Kuchenbauer F, Wen M, Kasaian K, Witty MF, Rosten P, Chen Y, Imren S, Duester G, Thompson DC, Humphries RK, Vasiliou V, Smith C. Aldehyde dehydrogenases are regulators of hematopoietic stem cell numbers and B-cell development. Exp Hematol. 2012 Apr; 40(4):318-29.e2. PMID: 22198153.
      View in: PubMed
    51. Gibson DS, Rooney ME, Finnegan S, Qiu J, Thompson DC, Labaer J, Pennington SR, Duncan MW. Biomarkers in rheumatology, now and in the future. Rheumatology (Oxford). 2012 Mar; 51(3):423-33. PMID: 22179724.
      View in: PubMed
    52. Jackson BC, Thompson DC, Wright MW, McAndrews M, Bernard A, Nebert DW, Vasiliou V. Update of the human secretoglobin (SCGB) gene superfamily and an example of 'evolutionary bloom' of androgen-binding protein genes within the mouse Scgb gene superfamily. Hum Genomics. 2011 Oct; 5(6):691-702. PMID: 22155607.
      View in: PubMed
    53. Marchitti SA, Chen Y, Thompson DC, Vasiliou V. Ultraviolet radiation: cellular antioxidant response and the role of ocular aldehyde dehydrogenase enzymes. Eye Contact Lens. 2011 Jul; 37(4):206-13. PMID: 21670692.
      View in: PubMed
    54. Monaghan MS, Cain JJ, Malone PM, Chapman TA, Walters RW, Thompson DC, Riedl ST. Educational technology use among US colleges and schools of pharmacy. Am J Pharm Educ. 2011 Jun 10; 75(5):87. PMID: 21829261.
      View in: PubMed
    55. Chiang PC, Thompson DC, Ghosh S, Heitmeier MR. A formulation-enabled preclinical efficacy assessment of a farnesoid X receptor agonist, GW4064, in hamsters and cynomolgus monkeys. J Pharm Sci. 2011 Nov; 100(11):4722-33. PMID: 21660973.
      View in: PubMed
    56. Jackson B, Brocker C, Thompson DC, Black W, Vasiliou K, Nebert DW, Vasiliou V. Update on the aldehyde dehydrogenase gene (ALDH) superfamily. Hum Genomics. 2011 May; 5(4):283-303. PMID: 21712190.
      View in: PubMed
    57. Chen Y, Koppaka V, Thompson DC, Vasiliou V. Focus on molecules: ALDH1A1: from lens and corneal crystallin to stem cell marker. Exp Eye Res. 2012 Sep; 102:105-6. PMID: 21536030.
      View in: PubMed
    58. Pollock JD, Love TP, Steffes BC, Thompson DC, Mellinger J, Haisch C. Is it possible to train surgeons for rural Africa? A report of a successful international program. World J Surg. 2011 Mar; 35(3):493-9. PMID: 21191583.
      View in: PubMed
    59. Chen Y, Orlicky DJ, Matsumoto A, Singh S, Thompson DC, Vasiliou V. Aldehyde dehydrogenase 1B1 (ALDH1B1) is a potential biomarker for human colon cancer. Biochem Biophys Res Commun. 2011 Feb 11; 405(2):173-9. PMID: 21216231.
      View in: PubMed
    60. Burger SK, Thompson DC, Ayers PW. Quantum mechanics/molecular mechanics strategies for docking pose refinement: distinguishing between binders and decoys in cytochrome C peroxidase. J Chem Inf Model. 2011 Jan 24; 51(1):93-101. PMID: 21133348.
      View in: PubMed
    61. Dalin P, Bean DW, Dudley TL, Carney VA, Eberts D, Gardner KT, Hebertson E, Jones EN, Kazmer DJ, Michels GJ, O'Meara SA, Thompson DC. Seasonal adaptations to day length in ecotypes of Diorhabda spp. (Coleoptera: Chrysomelidae) inform selection of agents against saltcedars (Tamarix spp.). Environ Entomol. 2010 Oct; 39(5):1666-75. PMID: 22546466.
      View in: PubMed
    62. Stagos D, Chen Y, Brocker C, Donald E, Jackson BC, Orlicky DJ, Thompson DC, Vasiliou V. Aldehyde dehydrogenase 1B1: molecular cloning and characterization of a novel mitochondrial acetaldehyde-metabolizing enzyme. Drug Metab Dispos. 2010 Oct; 38(10):1679-87. PMID: 20616185.
      View in: PubMed
    63. Chiang PC, South SA, Foster KA, Daniels JS, Wene SP, Albin LA, Thompson DC. Utilizing a novel tandem oral dosing strategy to enhance exposure of low-solubility drug candidates in a preclinical setting. J Pharm Sci. 2010 Jul; 99(7):3132-40. PMID: 20229600.
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    64. Hu Y, Yang S, Shilliday FB, Heyde BR, Mandrell KM, Robins RH, Xie J, Reding MT, Lai Y, Thompson DC. Novel metabolic bioactivation mechanism for a series of anti-inflammatory agents (2,5-diaminothiophene derivatives) mediated by cytochrome p450 enzymes. Drug Metab Dispos. 2010 Sep; 38(9):1522-31. PMID: 20530221.
      View in: PubMed
    65. Chiang PC, Hu Y, Blom JD, Thompson DC. Evaluating the suitability of using rat models for preclinical efficacy and side effects with inhaled corticosteroids nanosuspension formulations. Nanoscale Res Lett. 2010 Apr 10; 5(6):1010-9. PMID: 20672144.
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    66. Chiang PC, Kishore NN, Thompson DC. Combined use of pharmacokinetic modeling and a steady-state delivery approach allows early assessment of IkappaB kinase-2 (IKK-2) target safety and efficacy. J Pharm Sci. 2010 Mar; 99(3):1278-87. PMID: 19743500.
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    67. Thompson DC. Overview of TCE-HIV Grant Programs. J Evid Based Soc Work. 2010 Jan; 7(1):3-4. PMID: 20178020.
      View in: PubMed
    68. Baber JC, Thompson DC, Cross JB, Humblet C. GARD: a Generally Applicable Replacement for RMSD. J Chem Inf Model. 2009 Aug; 49(8):1889-900. PMID: 19618919.
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    69. Cross JB, Thompson DC, Rai BK, Baber JC, Fan KY, Hu Y, Humblet C. Comparison of several molecular docking programs: pose prediction and virtual screening accuracy. J Chem Inf Model. 2009 Jun; 49(6):1455-74. PMID: 19476350.
      View in: PubMed
    70. Mbalaviele G, Sommers CD, Bonar SL, Mathialagan S, Schindler JF, Guzova JA, Shaffer AF, Melton MA, Christine LJ, Tripp CS, Chiang PC, Thompson DC, Hu Y, Kishore N. A novel, highly selective, tight binding IkappaB kinase-2 (IKK-2) inhibitor: a tool to correlate IKK-2 activity to the fate and functions of the components of the nuclear factor-kappaB pathway in arthritis-relevant cells and animal models. J Pharmacol Exp Ther. 2009 Apr; 329(1):14-25. PMID: 19168710.
      View in: PubMed
    71. Thompson DC, Denny RA, Nilakantan R, Humblet C, Joseph-McCarthy D, Feyfant E. CONFIRM: connecting fragments found in receptor molecules. J Comput Aided Mol Des. 2008 Oct; 22(10):761-72. PMID: 18612831.
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    72. Rodríguez JI, Thompson DC, Ayers PW, Köster AM. Numerical integration of exchange-correlation energies and potentials using transformed sparse grids. J Chem Phys. 2008 Jun 14; 128(22):224103. PMID: 18554002.
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    73. Thompson DC, Humblet C, Joseph-McCarthy D. Investigation of MM-PBSA rescoring of docking poses. J Chem Inf Model. 2008 May; 48(5):1081-91. PMID: 18465849.
      View in: PubMed
    74. Hutzler JM, Melton RJ, Rumsey JM, Thompson DC, Rock DA, Wienkers LC. Assessment of the metabolism and intrinsic reactivity of a novel catechol metabolite. Chem Res Toxicol. 2008 May; 21(5):1125-33. PMID: 18407675.
      View in: PubMed
    75. Mitchell MD, Elrick MM, Walgren JL, Mueller RA, Morris DL, Thompson DC. Peptide-based in vitro assay for the detection of reactive metabolites. Chem Res Toxicol. 2008 Apr; 21(4):859-68. PMID: 18370411.
      View in: PubMed
    76. Joseph-McCarthy D, Baber JC, Feyfant E, Thompson DC, Humblet C. Lead optimization via high-throughput molecular docking. Curr Opin Drug Discov Devel. 2007 May; 10(3):264-74. PMID: 17554852.
      View in: PubMed
    77. Valles SM, Strong CA, Oi DH, Porter SD, Pereira RM, Vander Meer RK, Hashimoto Y, Hooper-Bùi LM, Sánchez-Arroyo H, Davis T, Karpakakunjaram V, Vail KM, Fudd Graham LC, Briano JA, Calcaterra LA, Gilbert LE, Ward R, Ward K, Oliver JB, Taniguchi G, Thompson DC. Phenology, distribution, and host specificity of Solenopsis invicta virus-1. J Invertebr Pathol. 2007 Sep; 96(1):18-27. PMID: 17412359.
      View in: PubMed
    78. Walgren JL, Mitchell MD, Whiteley LO, Thompson DC. Identification of novel peptide safety markers for exocrine pancreatic toxicity induced by cyanohydroxybutene. Toxicol Sci. 2007 Mar; 96(1):174-83. PMID: 17169978.
      View in: PubMed
    79. Walgren JL, Mitchell MD, Whiteley LO, Thompson DC. Evaluation of two novel peptide safety markers for exocrine pancreatic toxicity. Toxicol Sci. 2007 Mar; 96(1):184-93. PMID: 17169977.
      View in: PubMed
    80. Elrick MM, Walgren JL, Mitchell MD, Thompson DC. Proteomics: recent applications and new technologies. Basic Clin Pharmacol Toxicol. 2006 May; 98(5):432-41. PMID: 16635100.
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    81. Walgren JL, Mitchell MD, Thompson DC. Role of metabolism in drug-induced idiosyncratic hepatotoxicity. Crit Rev Toxicol. 2005 Apr-May; 35(4):325-61. PMID: 15989140.
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    82. Thompson DC, Alavi A. A comparison of Hartree-Fock and exact diagonalization solutions for a model two-electron system. J Chem Phys. 2005 Mar 22; 122(12):124107. PMID: 15836369.
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    83. Dwyer-Nield LD, Srebernak MC, Barrett BS, Ahn J, Cosper P, Meyer AM, Kisley LR, Bauer AK, Thompson DC, Malkinson AM. Cytokines differentially regulate the synthesis of prostanoid and nitric oxide mediators in tumorigenic versus non-tumorigenic mouse lung epithelial cell lines. Carcinogenesis. 2005 Jul; 26(7):1196-206. PMID: 15746162.
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    84. Walgren JL, Thompson DC. Application of proteomic technologies in the drug development process. Toxicol Lett. 2004 Apr 01; 149(1-3):377-85. PMID: 15093284.
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    85. Falla DL, Campbell CD, Fagan AE, Thompson DC, Jull GA. Relationship between cranio-cervical flexion range of motion and pressure change during the cranio-cervical flexion test. Man Ther. 2003 May; 8(2):92-6. PMID: 12890436.
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    86. Kisley LR, Barrett BS, Bauer AK, Dwyer-Nield LD, Barthel B, Meyer AM, Thompson DC, Malkinson AM. Genetic ablation of inducible nitric oxide synthase decreases mouse lung tumorigenesis. Cancer Res. 2002 Dec 01; 62(23):6850-6. PMID: 12460898.
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    87. Kisley LR, Barrett BS, Dwyer-Nield LD, Bauer AK, Thompson DC, Malkinson AM. Celecoxib reduces pulmonary inflammation but not lung tumorigenesis in mice. Carcinogenesis. 2002 Oct; 23(10):1653-60. PMID: 12376474.
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