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Daniel Hernandez-Saavedra

TitleInstructor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-MED
Phone303/724-6137

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Kassa B, Mickael C, Kumar R, Sanders L, Koyanagi D, Hernandez-Saavedra D, Tuder RM, Graham BB. Paclitaxel blocks Th2-mediated TGF-ß activation in Schistosoma mansoni-induced pulmonary hypertension. Pulm Circ. 2019 Jan-Mar; 9(1):2045894018820813. PMID: 30511588.
      View in: PubMed
    2. Graham BB, Kumar R, Mickael C, Kassa B, Koyanagi D, Sanders L, Zhang L, Perez M, Hernandez-Saavedra D, Valencia C, Dixon K, Harral J, Loomis Z, Irwin D, Nemkov T, D'Alessandro A, Stenmark KR, Tuder RM. Vascular Adaptation of the Right Ventricle in Experimental Pulmonary Hypertension. Am J Respir Cell Mol Biol. 2018 Oct; 59(4):479-489. PMID: 29851508.
      View in: PubMed
    3. Kumar R, Mickael C, Kassa B, Gebreab L, Robinson JC, Koyanagi DE, Sanders L, Barthel L, Meadows C, Fox D, Irwin D, Li M, McKeon BA, Riddle S, Dale Brown R, Morgan LE, Evans CM, Hernandez-Saavedra D, Bandeira A, Maloney JP, Bull TM, Janssen WJ, Stenmark KR, Tuder RM, Graham BB. TGF-ß activation by bone marrow-derived thrombospondin-1 causes Schistosoma- and hypoxia-induced pulmonary hypertension. Nat Commun. 2017 05 30; 8:15494. PMID: 28555642.
      View in: PubMed
    4. Hernandez-Saavedra D, Swain K, Tuder R, Petersen SV, Nozik-Grayck E. Redox Regulation of the Superoxide Dismutases SOD3 and SOD2 in the Pulmonary Circulation. Adv Exp Med Biol. 2017; 967:57-70. PMID: 29047081.
      View in: PubMed
    5. Hernández-Saavedra D, Sanders L, Perez MJ, Kosmider B, Smith LP, Mitchell JD, Yoshida T, Tuder RM. RTP801 Amplifies Nicotinamide Adenine Dinucleotide Phosphate Oxidase-4-Dependent Oxidative Stress Induced by Cigarette Smoke. Am J Respir Cell Mol Biol. 2017 01; 56(1):62-73. PMID: 27556956.
      View in: PubMed
    6. Nadon AM, Perez MJ, Hernandez-Saavedra D, Smith LP, Yang Y, Sanders LA, Gandjeva A, Chabon J, Koyanagi DE, Graham BB, Tuder RM, Schmidt EP. Rtp801 suppression of epithelial mTORC1 augments endotoxin-induced lung inflammation. Am J Pathol. 2014 Sep; 184(9):2382-9. PMID: 25016184; PMCID: PMC4188171.
    7. Díaz-Flores M, Cruz M, Duran-Reyes G, Munguia-Miranda C, Loza-Rodríguez H, Pulido-Casas E, Torres-Ramírez N, Gaja-Rodriguez O, Kumate J, Baiza-Gutman LA, Hernández-Saavedra D. Oral supplementation with glycine reduces oxidative stress in patients with metabolic syndrome, improving their systolic blood pressure. Can J Physiol Pharmacol. 2013 Oct; 91(10):855-60. PMID: 24144057.
      View in: PubMed
    8. Hernandez-Saavedra D, Quijano C, Demicheli V, Souza JM, Radi R, McCord JM. Thiol-sensitive mutant forms of human SOD2, L60F, and I58T: the role of Cys140. Free Radic Biol Med. 2010 May 01; 48(9):1202-10. PMID: 20144705.
      View in: PubMed
    9. Hernandez-Saavedra D, McCord JM. Association of a new intronic polymorphism of the SOD2 gene (G1677T) with cancer. Cell Biochem Funct. 2009 Jun; 27(4):223-7. PMID: 19405048.
      View in: PubMed
    10. Alonso AL, Munguía-Miranda C, Ramos-Ponce D, Hernandez-Saavedra D, Kumate J, Cruz M. Waist perimeter cutoff points and prediction of metabolic syndrome risk. A study in a Mexican population. Arch Med Res. 2008 Apr; 39(3):346-51. PMID: 18279709.
      View in: PubMed
    11. Panayiotidis MI, Stabler SP, Ahmad A, Pappa A, Legros LH, Hernandez-Saavedra D, Schneider BK, Allen RH, Vasiliou V, McCord JM, Kotb M, White CW. Activation of a novel isoform of methionine adenosyl transferase 2A and increased S-adenosylmethionine turnover in lung epithelial cells exposed to hyperoxia. Free Radic Biol Med. 2006 Jan 15; 40(2):348-58. PMID: 16413417.
      View in: PubMed
    12. Ling X, Cota-Gomez A, Flores NC, Hernandez-Saavedra D, McCord JM, Marecki JC, Haskins K, McDuffie M, Powers K, Kench J, Oka M, McMurtry I, Flores SC. Alterations in redox homeostasis and prostaglandins impair endothelial-dependent vasodilation in euglycemic autoimmune nonobese diabetic mice. Free Radic Biol Med. 2005 Oct 15; 39(8):1089-98. PMID: 16198235.
      View in: PubMed
    13. Hernandez-Saavedra D, Zhou H, McCord JM. Anti-inflammatory properties of a chimeric recombinant superoxide dismutase: SOD2/3. Biomed Pharmacother. 2005 May; 59(4):204-8. PMID: 15862716.
      View in: PubMed
    14. Bonder CS, Knight D, Hernandez-Saavedra D, McCord JM, Kubes P. Chimeric SOD2/3 inhibits at the endothelial-neutrophil interface to limit vascular dysfunction in ischemia-reperfusion. Am J Physiol Gastrointest Liver Physiol. 2004 Sep; 287(3):G676-84. PMID: 15087276.
      View in: PubMed
    15. Ng ES, Jourd'heuil D, McCord JM, Hernandez D, Yasui M, Knight D, Kubes P. Enhanced S-nitroso-albumin formation from inhaled NO during ischemia/reperfusion. Circ Res. 2004 Mar 05; 94(4):559-65. PMID: 14739156.
      View in: PubMed
    16. Cool CD, Rai PR, Yeager ME, Hernandez-Saavedra D, Serls AE, Bull TM, Geraci MW, Brown KK, Routes JM, Tuder RM, Voelkel NF. Expression of human herpesvirus 8 in primary pulmonary hypertension. N Engl J Med. 2003 Sep 18; 349(12):1113-22. PMID: 13679525.
      View in: PubMed
    17. Hernandez-Saavedra D, McCord JM. Paradoxical effects of thiol reagents on Jurkat cells and a new thiol-sensitive mutant form of human mitochondrial superoxide dismutase. Cancer Res. 2003 Jan 01; 63(1):159-63. PMID: 12517793.
      View in: PubMed
    18. Quijano C, Hernandez-Saavedra D, Castro L, McCord JM, Freeman BA, Radi R. Reaction of peroxynitrite with Mn-superoxide dismutase. Role of the metal center in decomposition kinetics and nitration. J Biol Chem. 2001 Apr 13; 276(15):11631-8. PMID: 11152462.
      View in: PubMed
    19. Seve M, Favier A, Osman M, Hernandez D, Vaitaitis G, Flores NC, McCord JM, Flores SC. The human immunodeficiency virus-1 Tat protein increases cell proliferation, alters sensitivity to zinc chelator-induced apoptosis, and changes Sp1 DNA binding in HeLa cells. Arch Biochem Biophys. 1999 Jan 15; 361(2):165-72. PMID: 9882443.
      View in: PubMed
    20. Tinoco R, Hernandez-Saavedra D, Ochoa JL, Vazquez-Duhalt R. Biochemical method for chlorine dioxide determination. Anal Biochem. 1996 Oct 01; 241(1):18-22. PMID: 8921159.
      View in: PubMed
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