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David Ross

TitleProfessor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOP-Administration
Phone303/724-7265

    Collapse Research 
    Collapse research activities and funding
    R01DK109964     (ROSS, DAVID)Apr 1, 2017 - Mar 31, 2022
    NIH
    Regulation of insulin signaling and sensitivity by the xenobiotic metabolizing enzyme NQO1
    Role: Principal Investigator
    R01ES018943     (ROSS, DAVID)Jun 4, 2010 - Mar 31, 2016
    NIH
    Novel Mechanisms of Quinone Toxicity
    Role: Principal Investigator
    R21HL095995     (ROSS, DAVID)Jul 30, 2009 - Jun 30, 2012
    NIH
    Targeting of NQ02 in CML
    Role: Principal Investigator
    R01CA114441     (ROSS, DAVID)Sep 30, 2005 - Jul 31, 2010
    NIH
    NQO1 Inhibitors and Pancreatic Cancer Therapy
    Role: Principal Investigator
    R01NS044613     (ROSS, DAVID)Jul 1, 2002 - Jun 30, 2009
    NIH
    NQ01, Oxidative Stress and Proteasomal Inhibition
    Role: Principal Investigator
    R01ES009554     (ROSS, DAVID)Jul 15, 1998 - Dec 4, 2002
    NIH
    NQO1 in Protection Against Benzene Toxicicity
    Role: Principal Investigator
    R01CA051210     (ROSS, DAVID)Jul 1, 1990 - Nov 30, 2017
    NIH
    Biochemical and molecular studies on NQO1. Design of less toxic Hsp90 inhibitors
    Role: Principal Investigator
    R01ES004112     (ROSS, DAVID)Jul 1, 1986 - Jun 30, 1997
    NIH
    METABOLIC BASIS OF BENZENE-INDUCED MYELOTOXICITY
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Ross D, Siegel D. The diverse functionality of NQO1 and its roles in redox control. Redox Biol. 2021 05; 41:101950. PMID: 33774477.
      View in: PubMed
    2. Siegel D, Baca SM, Thompson DC, Huntsman MM, Mower MM, Ross D. The effect of anodal/cathodal biphasic electrical stimulation on insulin release. J Cell Physiol. 2019 Feb 11. PMID: 30746686.
      View in: PubMed
    3. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 19056352.
      View in: PubMed
    4. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 19114859.
      View in: PubMed
    5. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 18825513.
      View in: PubMed
    6. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 23684743.
      View in: PubMed
    7. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 26096359.
      View in: PubMed
    8. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 3245231.
      View in: PubMed
    9. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 32731925.
      View in: PubMed
    10. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 33298924.
      View in: PubMed
    11. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 33360352.
      View in: PubMed
    12. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 27825764.
      View in: PubMed
    13. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 11410883.
      View in: PubMed
    14. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 28883796.
      View in: PubMed
    15. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 20970411.
      View in: PubMed
    16. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 21285336.
      View in: PubMed
    17. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 18635747.
      View in: PubMed
    18. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 22984577.
      View in: PubMed
    19. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 22687461.
      View in: PubMed
    20. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 16825487.
      View in: PubMed
    21. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 20378716.
      View in: PubMed
    22. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 12649308.
      View in: PubMed
    23. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 11888914.
      View in: PubMed
    24. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 11735396.
      View in: PubMed
    25. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 11154736.
      View in: PubMed
    26. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 11600935.
      View in: PubMed
    27. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 11377380.
      View in: PubMed
    28. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 10393963.
      View in: PubMed
    29. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 9328142.
      View in: PubMed
    30. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 9000600.
      View in: PubMed
    31. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 1737339.
      View in: PubMed
    32. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 8242863.
      View in: PubMed
    33. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 1769608.
      View in: PubMed
    34. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 2343455.
      View in: PubMed
    35. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 9748120.
      View in: PubMed
    36. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 2832975.
      View in: PubMed
    37. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 22147753.
      View in: PubMed
    38. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 17034135.
      View in: PubMed
    39. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 2877394.
      View in: PubMed
    40. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 3017211.
      View in: PubMed
    41. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 2992602.
      View in: PubMed
    42. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 6095833.
      View in: PubMed
    43. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 1733045.
      View in: PubMed
    44. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 9710951.
      View in: PubMed
    45. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 2262258.
      View in: PubMed
    46. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 17164365.
      View in: PubMed
    47. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 9649587.
      View in: PubMed
    48. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 11753387.
      View in: PubMed
    49. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 10428770.
      View in: PubMed
    50. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 15297809.
      View in: PubMed
    51. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 16054862.
      View in: PubMed
    52. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 12232835.
      View in: PubMed
    53. Rulifson G, Bielefeldt AR. Evolution of Students' Varied Conceptualizations About Socially Responsible Engineering: A Four Year Longitudinal Study. Sci Eng Ethics. 2019 06; 25(3):939-974. PMID: 15466671.
      View in: PubMed
    54. Siegel D, Dehn DD, Bokatzian SS, Quinn K, Backos DS, Di Francesco A, Bernier M, Reisdorph N, de Cabo R, Ross D. Redox modulation of NQO1. PLoS One. 2018; 13(1):e0190717. PMID: 29298345.
      View in: PubMed
    55. Black HA, Leighton DJ, Cleary EM, Rose E, Stephenson L, Colville S, Ross D, Warner J, Porteous M, Gorrie GH, Swingler R, Goldstein D, Harms MB, Connick P, Pal S, Aitman TJ, Chandran S. Genetic epidemiology of motor neuron disease-associated variants in the Scottish population. Neurobiol Aging. 2017 03; 51:178.e11-178.e20. PMID: 28089114.
      View in: PubMed
    56. Grskovic M, Hiller DJ, Eubank LA, Sninsky JJ, Christopherson C, Collins JP, Thompson K, Song M, Wang YS, Ross D, Nelles MJ, Yee JP, Wilber JC, Crespo-Leiro MG, Scott SL, Woodward RN. Validation of a Clinical-Grade Assay to Measure Donor-Derived Cell-Free DNA in Solid Organ Transplant Recipients. J Mol Diagn. 2016 11; 18(6):890-902. PMID: 27727019.
      View in: PubMed
    57. Di Francesco A, Di Germanio C, Panda AC, Huynh P, Peaden R, Navas-Enamorado I, Bastian P, Lehrmann E, Diaz-Ruiz A, Ross D, Siegel D, Martindale JL, Bernier M, Gorospe M, Abdelmohsen K, de Cabo R. Novel RNA-binding activity of NQO1 promotes SERPINA1 mRNA translation. Free Radic Biol Med. 2016 10; 99:225-233. PMID: 27515817.
      View in: PubMed
    58. Sanders H, Qu K, Li H, Ma L, Barlan C, Zhang X, Prentice J, Wolfson D, Crossley B, Sferruzza A, Sninsky J, Ross D, Grupe A, Catanese J, Hantash F, Waldman F. Mutation Yield of a 34-Gene Solid Tumor Panel in Community-Based Tumor Samples. Mol Diagn Ther. 2016 06; 20(3):241-53. PMID: 27084556.
      View in: PubMed
    59. Xiong R, Zhou W, Siegel D, Kitson RR, Freed CR, Moody CJ, Ross D. A Novel Hsp90 Inhibitor Activates Compensatory Heat Shock Protein Responses and Autophagy and Alleviates Mutant A53T a-Synuclein Toxicity. Mol Pharmacol. 2015 Dec; 88(6):1045-54. PMID: 26405178.
      View in: PubMed
    60. Yan C, Liu D, Li L, Wempe MF, Guin S, Khanna M, Meier J, Hoffman B, Owens C, Wysoczynski CL, Nitz MD, Knabe WE, Ahmed M, Brautigan DL, Paschal BM, Schwartz MA, Jones DN, Ross D, Meroueh SO, Theodorescu D. Discovery and characterization of small molecules that target the GTPase Ral. Nature. 2014 Nov 20; 515(7527):443-7. PMID: 25219851.
      View in: PubMed
    61. Xiong R, Siegel D, Ross D. Quinone-induced protein handling changes: implications for major protein handling systems in quinone-mediated toxicity. Toxicol Appl Pharmacol. 2014 Oct 15; 280(2):285-95. PMID: 25151970.
      View in: PubMed
    62. Inman M, Visconti A, Yan C, Siegel D, Ross D, Moody CJ. Antitumour indolequinones: synthesis and activity against human pancreatic cancer cells. Org Biomol Chem. 2014 Jul 21; 12(27):4848-61. PMID: 24848343.
      View in: PubMed
    63. Carvalho C, Siegel D, Inman M, Xiong R, Ross D, Moody CJ. Benzofuranquinones as inhibitors of indoleamine 2,3-dioxygenase (IDO). Synthesis and biological evaluation. Org Biomol Chem. 2014 May 07; 12(17):2663-74. PMID: 24608884.
      View in: PubMed
    64. Chang CH, Drechsel DA, Kitson RR, Siegel D, You Q, Backos DS, Ju C, Moody CJ, Ross D. 19-substituted benzoquinone ansamycin heat shock protein-90 inhibitors: biological activity and decreased off-target toxicity. Mol Pharmacol. 2014 Jun; 85(6):849-57. PMID: 24682466.
      View in: PubMed
    65. Ferguson L, Grant AD, Lewis J, Kielmann K, Watson-Jones D, Vusha S, Ong'ech JO, Ross DA. Linking women who test HIV-positive in pregnancy-related services to HIV care and treatment services in Kenya: a mixed methods prospective cohort study. PLoS One. 2014; 9(3):e89764. PMID: 24646492.
      View in: PubMed
    66. Greim H, Kaden DA, Larson RA, Palermo CM, Rice JM, Ross D, Snyder R. The bone marrow niche, stem cells, and leukemia: impact of drugs, chemicals, and the environment. Ann N Y Acad Sci. 2014 Mar; 1310:7-31. PMID: 24495159.
      View in: PubMed
    67. Pasceri R, Siegel D, Ross D, Moody CJ. Aminophenoxazinones as inhibitors of indoleamine 2,3-dioxygenase (IDO). Synthesis of exfoliazone and chandrananimycin A. J Med Chem. 2013 Apr 25; 56(8):3310-7. PMID: 23521768.
      View in: PubMed
    68. Kitson RR, Chang CH, Xiong R, Williams HE, Davis AL, Lewis W, Dehn DL, Siegel D, Roe SM, Prodromou C, Ross D, Moody CJ. Synthesis of 19-substituted geldanamycins with altered conformations and their binding to heat shock protein Hsp90. Nat Chem. 2013 Apr; 5(4):307-14. PMID: 23511419.
      View in: PubMed
    69. Quentin W, Terris-Prestholt F, Changalucha J, Soteli S, Edmunds WJ, Hutubessy R, Ross DA, Kapiga S, Hayes R, Watson-Jones D. Costs of delivering human papillomavirus vaccination to schoolgirls in Mwanza Region, Tanzania. BMC Med. 2012 Nov 13; 10:137. PMID: 23148516.
      View in: PubMed
    70. Baisley K, Doyle AM, Changalucha J, Maganja K, Watson-Jones D, Hayes R, Ross D. Uptake of voluntary counselling and testing among young people participating in an HIV prevention trial: comparison of opt-out and opt-in strategies. PLoS One. 2012; 7(7):e42108. PMID: 22848722.
      View in: PubMed
    71. Watson-Jones D, Baisley K, Ponsiano R, Lemme F, Remes P, Ross D, Kapiga S, Mayaud P, de Sanjosé S, Wight D, Changalucha J, Hayes R. Human papillomavirus vaccination in Tanzanian schoolgirls: cluster-randomized trial comparing 2 vaccine-delivery strategies. J Infect Dis. 2012 Sep 01; 206(5):678-86. PMID: 22711908.
      View in: PubMed
    72. Siegel D, Yan C, Ross D. NAD(P)H:quinone oxidoreductase 1 (NQO1) in the sensitivity and resistance to antitumor quinones. Biochem Pharmacol. 2012 Apr 15; 83(8):1033-40. PMID: 22209713.
      View in: PubMed
    73. Luke MM, Berger K, Rowland CM, Catanese JJ, Tong CH, Ross DA, Garcia V, Kuhlenbaeumer G, Ringelstein EB, Pullinger CR, Malloy MJ, Deedwania P, Ellis SG, Kane JP, Devlin JJ, Lalouschek W, Mannhalter C. Polymorphisms and noncardioembolic stroke in three case-control studies. Cerebrovasc Dis. 2012; 33(1):80-5. PMID: 22134093.
      View in: PubMed
    74. Yan C, Dufour M, Siegel D, Reigan P, Gomez J, Shieh B, Moody CJ, Ross D. Indolequinone inhibitors of NRH:quinone oxidoreductase 2. Characterization of the mechanism of inhibition in both cell-free and cellular systems. Biochemistry. 2011 Aug 09; 50(31):6678-88. PMID: 21718050.
      View in: PubMed
    75. Dufour M, Yan C, Siegel D, Colucci MA, Jenner M, Oldham NJ, Gomez J, Reigan P, Li Y, De Matteis CI, Ross D, Moody CJ. Mechanism-based inhibition of quinone reductase 2 (NQO2): selectivity for NQO2 over NQO1 and structural basis for flavoprotein inhibition. Chembiochem. 2011 May 16; 12(8):1203-8. PMID: 21506232.
      View in: PubMed
    76. Siegel D, Shieh B, Yan C, Kepa JK, Ross D. Role for NAD(P)H:quinone oxidoreductase 1 and manganese-dependent superoxide dismutase in 17-(allylamino)-17-demethoxygeldanamycin-induced heat shock protein 90 inhibition in pancreatic cancer cells. J Pharmacol Exp Ther. 2011 Mar; 336(3):874-80. PMID: 21156818.
      View in: PubMed
    77. Chan KM, Rajab NF, Siegel D, Din LB, Ross D, Inayat-Hussain SH. Goniothalamin induces coronary artery smooth muscle cells apoptosis: the p53-dependent caspase-2 activation pathway. Toxicol Sci. 2010 Aug; 116(2):533-48. PMID: 20498002.
      View in: PubMed
    78. Inayat-Hussain SH, Ibrahim HA, Siew EL, Rajab NF, Chan KM, Ross D. Modulation of the benzene metabolite hydroquinone induced toxicity: evidence for an important role of fau. Chem Biol Interact. 2010 Mar 19; 184(1-2):310-2. PMID: 20025857.
      View in: PubMed
    79. Nolan KA, Doncaster JR, Dunstan MS, Scott KA, Frenkel AD, Siegel D, Ross D, Barnes J, Levy C, Leys D, Whitehead RC, Stratford IJ, Bryce RA. Synthesis and biological evaluation of coumarin-based inhibitors of NAD(P)H: quinone oxidoreductase-1 (NQO1). J Med Chem. 2009 Nov 26; 52(22):7142-56. PMID: 19877692.
      View in: PubMed
    80. Ross D, Zhou H. Relationships between metabolic and non-metabolic susceptibility factors in benzene toxicity. Chem Biol Interact. 2010 Mar 19; 184(1-2):222-8. PMID: 19941840.
      View in: PubMed
    81. Ross DA, Marks LE. Absolute pitch in children prior to the beginning of musical training. Ann N Y Acad Sci. 2009 Jul; 1169:199-204. PMID: 19673781.
      View in: PubMed
    82. Zhou H, Kepa JK, Siegel D, Miura S, Hiraki Y, Ross D. Benzene metabolite hydroquinone up-regulates chondromodulin-I and inhibits tube formation in human bone marrow endothelial cells. Mol Pharmacol. 2009 Sep; 76(3):579-87. PMID: 19525446.
      View in: PubMed
    83. Yan C, Shieh B, Reigan P, Zhang Z, Colucci MA, Chilloux A, Newsome JJ, Siegel D, Chan D, Moody CJ, Ross D. Potent activity of indolequinones against human pancreatic cancer: identification of thioredoxin reductase as a potential target. Mol Pharmacol. 2009 Jul; 76(1):163-72. PMID: 19364812.
      View in: PubMed
    84. Guo W, Siegel D, Ross D. Stability of the Hsp90 inhibitor 17AAG hydroquinone and prevention of metal-catalyzed oxidation. J Pharm Sci. 2008 Dec; 97(12):5147-57. PMID: 18393300.
      View in: PubMed
    85. Yan C, Kepa JK, Siegel D, Stratford IJ, Ross D. Dissecting the role of multiple reductases in bioactivation and cytotoxicity of the antitumor agent 2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone (RH1). Mol Pharmacol. 2008 Dec; 74(6):1657-65. PMID: 18794327.
      View in: PubMed
    86. Shiffman D, Kane JP, Louie JZ, Arellano AR, Ross DA, Catanese JJ, Malloy MJ, Ellis SG, Devlin JJ. Analysis of 17,576 potentially functional SNPs in three case-control studies of myocardial infarction. PLoS One. 2008 Aug 06; 3(8):e2895. PMID: 18682748.
      View in: PubMed
    87. Ross DA, Lee S, Reiser V, Xue J, Alves K, Vaidya S, Kreamer A, Mull R, Hudak E, Hare T, Detmers PA, Lingham R, Ferrer M, Strulovici B, Santini F. Multiplexed assays by high-content imaging for assessment of GPCR activity. J Biomol Screen. 2008 Jul; 13(6):449-55. PMID: 18519922.
      View in: PubMed
    88. Watson-Jones D, Weiss HA, Rusizoka M, Changalucha J, Baisley K, Mugeye K, Tanton C, Ross D, Everett D, Clayton T, Balira R, Knight L, Hambleton I, Le Goff J, Belec L, Hayes R. Effect of herpes simplex suppression on incidence of HIV among women in Tanzania. N Engl J Med. 2008 Apr 10; 358(15):1560-71. PMID: 18337596.
      View in: PubMed
    89. Awadallah NS, Dehn D, Shah RJ, Russell Nash S, Chen YK, Ross D, Bentz JS, Shroyer KR. NQO1 expression in pancreatic cancer and its potential use as a biomarker. Appl Immunohistochem Mol Morphol. 2008 Jan; 16(1):24-31. PMID: 18091324.
      View in: PubMed
    90. Li Y, Grupe A, Rowland C, Holmans P, Segurado R, Abraham R, Jones L, Catanese J, Ross D, Mayo K, Martinez M, Hollingworth P, Goate A, Cairns NJ, Racette BA, Perlmutter JS, O'Donovan MC, Morris JC, Brayne C, Rubinsztein DC, Lovestone S, Thal LJ, Owen MJ, Williams J. Evidence that common variation in NEDD9 is associated with susceptibility to late-onset Alzheimer's and Parkinson's disease. Hum Mol Genet. 2008 Mar 01; 17(5):759-67. PMID: 18063669.
      View in: PubMed
    91. Nolan KA, Zhao H, Faulder PF, Frenkel AD, Timson DJ, Siegel D, Ross D, Burke TR, Stratford IJ, Bryce RA. Coumarin-based inhibitors of human NAD(P)H:quinone oxidoreductase-1. Identification, structure-activity, off-target effects and in vitro human pancreatic cancer toxicity. J Med Chem. 2007 Dec 13; 50(25):6316-25. PMID: 17999461.
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    92. Everett DB, Weiss HA, Changalucha J, Anemona A, Chirwa T, Ross DA, Watson-Jones D, Parry JV, Hayes R, Mabey DC. Low specificity of the Murex fourth-generation HIV enzyme immunoassay in Tanzanian adolescents. Trop Med Int Health. 2007 Nov; 12(11):1323-6. PMID: 17949396.
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    93. Colucci MA, Reigan P, Siegel D, Chilloux A, Ross D, Moody CJ. Synthesis and evaluation of 3-aryloxymethyl-1,2-dimethylindole-4,7-diones as mechanism-based inhibitors of NAD(P)H:quinone oxidoreductase 1 (NQO1) activity. J Med Chem. 2007 Nov 15; 50(23):5780-9. PMID: 17944451.
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    94. Vallely A, Shagi C, Kasindi S, Desmond N, Lees S, Chiduo B, Hayes R, Allen C, Ross D. The benefits of participatory methodologies to develop effective community dialogue in the context of a microbicide trial feasibility study in Mwanza, Tanzania. BMC Public Health. 2007 Jul 02; 7:133. PMID: 17697333.
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    95. Zafar KS, Inayat-Hussain SH, Ross D. A comparative study of proteasomal inhibition and apoptosis induced in N27 mesencephalic cells by dopamine and MG132. J Neurochem. 2007 Aug; 102(3):913-21. PMID: 17504267.
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    96. Reigan P, Colucci MA, Siegel D, Chilloux A, Moody CJ, Ross D. Development of indolequinone mechanism-based inhibitors of NAD(P)H:quinone oxidoreductase 1 (NQO1): NQO1 inhibition and growth inhibitory activity in human pancreatic MIA PaCa-2 cancer cells. Biochemistry. 2007 May 22; 46(20):5941-50. PMID: 17455910.
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    97. Atwal GS, Bond GL, Metsuyanim S, Papa M, Friedman E, Distelman-Menachem T, Ben Asher E, Lancet D, Ross DA, Sninsky J, White TJ, Levine AJ, Yarden R. Haplotype structure and selection of the MDM2 oncogene in humans. Proc Natl Acad Sci U S A. 2007 Mar 13; 104(11):4524-9. PMID: 17360557.
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    98. Lennard ML, Hikima J, Ross DA, Kruiswijk CP, Wilson MR, Miller NW, Warr GW. Characterization of an Oct1 orthologue in the channel catfish, Ictalurus punctatus: a negative regulator of immunoglobulin gene transcription? BMC Mol Biol. 2007 Jan 31; 8:8. PMID: 17266766.
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    99. Zhu H, Jia Z, Mahaney JE, Ross D, Misra HP, Trush MA, Li Y. The highly expressed and inducible endogenous NAD(P)H:quinone oxidoreductase 1 in cardiovascular cells acts as a potential superoxide scavenger. Cardiovasc Toxicol. 2007; 7(3):202-11. PMID: 17901563.
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    100. Siegel D, Kepa JK, Ross D. Biochemical and genetic analysis of NAD(P)H:quinone oxidoreductase 1 (NQO1). Curr Protoc Toxicol. 2007; Chapter 4:Unit4.22. PMID: 23045144.
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    101. Watson-Jones D, Weiss HA, Changalucha JM, Todd J, Gumodoka B, Bulmer J, Balira R, Ross D, Mugeye K, Hayes R, Mabey D. Adverse birth outcomes in United Republic of Tanzania--impact and prevention of maternal risk factors. Bull World Health Organ. 2007 Jan; 85(1):9-18. PMID: 17242753.
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    102. Dehn DL, Siegel D, Zafar KS, Reigan P, Swann E, Moody CJ, Ross D. 5-Methoxy-1,2-dimethyl-3-[(4-nitrophenoxy)methyl]indole-4,7-dione, a mechanism-based inhibitor of NAD(P)H:quinone oxidoreductase 1, exhibits activity against human pancreatic cancer in vitro and in vivo. Mol Cancer Ther. 2006 Jul; 5(7):1702-9. PMID: 16891456.
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    103. Zafar KS, Siegel D, Ross D. A potential role for cyclized quinones derived from dopamine, DOPA, and 3,4-dihydroxyphenylacetic acid in proteasomal inhibition. Mol Pharmacol. 2006 Sep; 70(3):1079-86. PMID: 16790533.
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    104. Zhu H, Zhang L, Itoh K, Yamamoto M, Ross D, Trush MA, Zweier JL, Li Y. Nrf2 controls bone marrow stromal cell susceptibility to oxidative and electrophilic stress. Free Radic Biol Med. 2006 Jul 01; 41(1):132-43. PMID: 16781461.
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    105. Huang H, Shiffman ML, Cheung RC, Layden TJ, Friedman S, Abar OT, Yee L, Chokkalingam AP, Schrodi SJ, Chan J, Catanese JJ, Leong DU, Ross D, Hu X, Monto A, McAllister LB, Broder S, White T, Sninsky JJ, Wright TL. Identification of two gene variants associated with risk of advanced fibrosis in patients with chronic hepatitis C. Gastroenterology. 2006 May; 130(6):1679-87. PMID: 16697732.
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    106. Vasiliou V, Ross D, Nebert DW. Update of the NAD(P)H:quinone oxidoreductase (NQO) gene family. Hum Genomics. 2006 Mar; 2(5):329-35. PMID: 16595077.
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    107. Todd J, Grosskurth H, Changalucha J, Obasi A, Mosha F, Balira R, Orroth K, Hugonnet S, Pujades M, Ross D, Gavyole A, Mabey D, Hayes R. Risk factors influencing HIV infection incidence in a rural African population: a nested case-control study. J Infect Dis. 2006 Feb 01; 193(3):458-66. PMID: 16388496.
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    108. Guo W, Reigan P, Siegel D, Zirrolli J, Gustafson D, Ross D. Formation of 17-allylamino-demethoxygeldanamycin (17-AAG) hydroquinone by NAD(P)H:quinone oxidoreductase 1: role of 17-AAG hydroquinone in heat shock protein 90 inhibition. Cancer Res. 2005 Nov 01; 65(21):10006-15. PMID: 16267026.
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    109. Ross D. Functions and distribution of NQO1 in human bone marrow: potential clues to benzene toxicity. Chem Biol Interact. 2005 May 30; 153-154:137-46. PMID: 15935810.
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    110. Inayat-Hussain SH, Ross D. Intrinsic pathway of hydroquinone induced apoptosis occurs via both caspase-dependent and caspase-independent mechanisms. Chem Res Toxicol. 2005 Mar; 18(3):420-7. PMID: 15777082.
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    111. Dehn DL, Inayat-Hussain SH, Ross D. RH1 induces cellular damage in an NAD(P)H:quinone oxidoreductase 1-dependent manner: relationship between DNA cross-linking, cell cycle perturbations, and apoptosis. J Pharmacol Exp Ther. 2005 May; 313(2):771-9. PMID: 15665137.
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    112. Bironaite D, Siegel D, Moran JL, Weksler BB, Ross D. Stimulation of endothelial IL-8 (eIL-8) production and apoptosis by phenolic metabolites of benzene in HL-60 cells and human bone marrow endothelial cells. Chem Biol Interact. 2004 Oct 15; 149(2-3):177-88. PMID: 15586939.
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    113. Ross D. Quinone reductases multitasking in the metabolic world. Drug Metab Rev. 2004 Oct; 36(3-4):639-54. PMID: 15554240.
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    114. van Muiswinkel FL, de Vos RA, Bol JG, Andringa G, Jansen Steur EN, Ross D, Siegel D, Drukarch B. Expression of NAD(P)H:quinone oxidoreductase in the normal and Parkinsonian substantia nigra. Neurobiol Aging. 2004 Oct; 25(9):1253-62. PMID: 15312971.
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    115. Bironaite D, Siegel D, Moran JL, Weksler BB, Ross D. Stimulation of endothelial IL-8 (eIL-8) production and apoptosis by phenolic metabolites of benzene in HL-60 cells and human bone marrow endothelial cells. Chem Biol Interact. 2004 Aug 10; 149(1):37-49. PMID: 15356918.
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    116. Dehn DL, Winski SL, Ross D. Development of a new isogenic cell-xenograft system for evaluation of NAD(P)H:quinone oxidoreductase-directed antitumor quinones: evaluation of the activity of RH1. Clin Cancer Res. 2004 May 01; 10(9):3147-55. PMID: 15131056.
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    117. Siegel D, Gustafson DL, Dehn DL, Han JY, Boonchoong P, Berliner LJ, Ross D. NAD(P)H:quinone oxidoreductase 1: role as a superoxide scavenger. Mol Pharmacol. 2004 May; 65(5):1238-47. PMID: 15102952.
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    118. Ross DA, Rao PK, Kadesch T. Dual roles for the Notch target gene Hes-1 in the differentiation of 3T3-L1 preadipocytes. Mol Cell Biol. 2004 Apr; 24(8):3505-13. PMID: 15060169.
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    119. Todd J, Changalucha J, Ross DA, Mosha F, Obasi AI, Plummer M, Balira R, Grosskurth H, Mabey DC, Hayes R. The sexual health of pupils in years 4 to 6 of primary schools in rural Tanzania. Sex Transm Infect. 2004 Feb; 80(1):35-42. PMID: 14755033.
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    120. Ross D, Siegel D. NAD(P)H:quinone oxidoreductase 1 (NQO1, DT-diaphorase), functions and pharmacogenetics. Methods Enzymol. 2004; 382:115-44. PMID: 15047100.
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    121. Kepa JK, Ross D. Differential expression of the antioxidant response element within the hNQO1 promoter in NSCLC versus SCLC. Biochem Biophys Res Commun. 2003 Nov 14; 311(2):446-53. PMID: 14592434.
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    122. Sarbia M, Bitzer M, Siegel D, Ross D, Schulz WA, Zotz RB, Kiel S, Geddert H, Kandemir Y, Walter A, Willers R, Gabbert HE. Association between NAD(P)H: quinone oxidoreductase 1 (NQ01) inactivating C609T polymorphism and adenocarcinoma of the upper gastrointestinal tract. Int J Cancer. 2003 Nov 10; 107(3):381-6. PMID: 14506737.
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    123. Ross DA, Olson IR, Gore JC. Absolute pitch does not depend on early musical training. Ann N Y Acad Sci. 2003 Nov; 999:522-6. PMID: 14681178.
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    124. Dehn DL, Siegel D, Swann E, Moody CJ, Ross D. Biochemical, cytotoxic, and genotoxic effects of ES936, a mechanism-based inhibitor of NAD(P)H:quinone oxidoreductase 1, in cellular systems. Mol Pharmacol. 2003 Sep; 64(3):714-20. PMID: 12920209.
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    125. Zhang J, Schulz WA, Li Y, Wang R, Zotz R, Wen D, Siegel D, Ross D, Gabbert HE, Sarbia M. Association of NAD(P)H: quinone oxidoreductase 1 (NQO1) C609T polymorphism with esophageal squamous cell carcinoma in a German Caucasian and a northern Chinese population. Carcinogenesis. 2003 May; 24(5):905-9. PMID: 12771035.
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    126. Anwar A, Dehn D, Siegel D, Kepa JK, Tang LJ, Pietenpol JA, Ross D. Interaction of human NAD(P)H:quinone oxidoreductase 1 (NQO1) with the tumor suppressor protein p53 in cells and cell-free systems. J Biol Chem. 2003 Mar 21; 278(12):10368-73. PMID: 12529318.
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    127. Watson-Jones D, Changalucha J, Gumodoka B, Weiss H, Rusizoka M, Ndeki L, Whitehouse A, Balira R, Todd J, Ngeleja D, Ross D, Buvé A, Hayes R, Mabey D. Syphilis in pregnancy in Tanzania. I. Impact of maternal syphilis on outcome of pregnancy. J Infect Dis. 2002 Oct 01; 186(7):940-7. PMID: 12232834.
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    128. Cioffi CC, Pollenz RS, Middleton DL, Wilson MR, Miller NW, William Clem L, Warr GW, Ross DA. Oct2 transcription factor of a teleost fish: activation domains and function from an enhancer. Arch Biochem Biophys. 2002 Aug 01; 404(1):55-61. PMID: 12127069.
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    129. Hugonnet S, Mosha F, Todd J, Mugeye K, Klokke A, Ndeki L, Ross D, Grosskurth H, Hayes R. Incidence of HIV infection in stable sexual partnerships: a retrospective cohort study of 1802 couples in Mwanza Region, Tanzania. J Acquir Immune Defic Syndr. 2002 May 01; 30(1):73-80. PMID: 12048366.
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    130. Changalucha J, Grosskurth H, Mwita W, Todd J, Ross D, Mayaud P, Mahamoud A, Klokke A, Mosha F, Hayes R, Mabey D. Comparison of HIV prevalences in community-based and antenatal clinic surveys in rural Mwanza, Tanzania. AIDS. 2002 Mar 08; 16(4):661-5. PMID: 11873011.
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    131. del Mar Pujades Rodríguez M, Obasi A, Mosha F, Todd J, Brown D, Changalucha J, Mabey D, Ross D, Grosskurth H, Hayes R. Herpes simplex virus type 2 infection increases HIV incidence: a prospective study in rural Tanzania. AIDS. 2002 Feb 15; 16(3):451-62. PMID: 11834958.
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    132. Anwar A, Siegel D, Kepa JK, Ross D. Interaction of the molecular chaperone Hsp70 with human NAD(P)H:quinone oxidoreductase 1. J Biol Chem. 2002 Apr 19; 277(16):14060-7. PMID: 11821413.
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    133. Siegel D, Ryder J, Ross D. NAD(P)H: quinone oxidoreductase 1 expression in human bone marrow endothelial cells. Toxicol Lett. 2001 Dec 15; 125(1-3):93-8. PMID: 11701227.
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    134. Inayat-Hussain SH, Winski SL, Ross D. Differential involvement of caspases in hydroquinone-induced apoptosis in human leukemic hl-60 and jurkat cells. Toxicol Appl Pharmacol. 2001 Sep 01; 175(2):95-103. PMID: 11543641.
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    135. Bachmanov AA, Li X, Reed DR, Ohmen JD, Li S, Chen Z, Tordoff MG, de Jong PJ, Wu C, West DB, Chatterjee A, Ross DA, Beauchamp GK. Positional cloning of the mouse saccharin preference (Sac) locus. Chem Senses. 2001 Sep; 26(7):925-33. PMID: 11555487.
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    136. Rickman DS, Tyagi R, Zhu XX, Bobek MP, Song S, Blaivas M, Misek DE, Israel MA, Kurnit DM, Ross DA, Kish PE, Hanash SM. The gene for the axonal cell adhesion molecule TAX-1 is amplified and aberrantly expressed in malignant gliomas. Cancer Res. 2001 Mar 01; 61(5):2162-8. PMID: 11280781.
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    137. Siegel D, Anwar A, Winski SL, Kepa JK, Zolman KL, Ross D. Rapid polyubiquitination and proteasomal degradation of a mutant form of NAD(P)H:quinone oxidoreductase 1. Mol Pharmacol. 2001 Feb; 59(2):263-8. PMID: 11160862.
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    138. Ross D. The role of metabolism and specific metabolites in benzene-induced toxicity: evidence and issues. J Toxicol Environ Health A. 2000 Nov; 61(5-6):357-72. PMID: 11086940.
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    139. Siegel D, Ross D. Immunodetection of NAD(P)H:quinone oxidoreductase 1 (NQO1) in human tissues. Free Radic Biol Med. 2000 Aug; 29(3-4):246-53. PMID: 11035253.
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    140. Schelonka LP, Siegel D, Wilson MW, Meininger A, Ross D. Immunohistochemical localization of NQO1 in epithelial dysplasia and neoplasia and in donor eyes. Invest Ophthalmol Vis Sci. 2000 Jun; 41(7):1617-22. PMID: 10845577.
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    141. Faig M, Bianchet MA, Talalay P, Chen S, Winski S, Ross D, Amzel LM. Structures of recombinant human and mouse NAD(P)H:quinone oxidoreductases: species comparison and structural changes with substrate binding and release. Proc Natl Acad Sci U S A. 2000 Mar 28; 97(7):3177-82. PMID: 10706635.
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    142. Fu Y, Cheng WH, Ross DA, Lei Xg. Cellular glutathione peroxidase protects mice against lethal oxidative stress induced by various doses of diquat. Proc Soc Exp Biol Med. 1999 Nov; 222(2):164-9. PMID: 10564541.
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    143. Fu Y, Cheng WH, Porres JM, Ross DA, Lei XG. Knockout of cellular glutathione peroxidase gene renders mice susceptible to diquat-induced oxidative stress. Free Radic Biol Med. 1999 Sep; 27(5-6):605-11. PMID: 10490281.
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    144. McGuinness SM, Johansson R, Lundstrom J, Ross D. Induction of apoptosis by remoxipride metabolites in HL60 and CD34+/CD19- human bone marrow progenitor cells: potential relevance to remoxipride-induced aplastic anemia. Chem Biol Interact. 1999 Aug 01; 121(3):253-65. PMID: 10462057.
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    145. Kepa JK, Ross D. DT-diaphorase activity in NSCLC and SCLC cell lines: a role for fos/jun regulation. Br J Cancer. 1999 Apr; 79(11-12):1679-84. PMID: 10206277.
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    146. Siegel D, McGuinness SM, Winski SL, Ross D. Genotype-phenotype relationships in studies of a polymorphism in NAD(P)H:quinone oxidoreductase 1. Pharmacogenetics. 1999 Feb; 9(1):113-21. PMID: 10208650.
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    147. Winski SL, Hargreaves RH, Butler J, Ross D. A new screening system for NAD(P)H:quinone oxidoreductase (NQO1)-directed antitumor quinones: identification of a new aziridinylbenzoquinone, RH1, as a NQO1-directed antitumor agent. Clin Cancer Res. 1998 Dec; 4(12):3083-8. PMID: 9865924.
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    148. Beall HD, Winski S, Swann E, Hudnott AR, Cotterill AS, O'Sullivan N, Green SJ, Bien R, Siegel D, Ross D, Moody CJ. Indolequinone antitumor agents: correlation between quinone structure, rate of metabolism by recombinant human NAD(P)H:quinone oxidoreductase, and in vitro cytotoxicity. J Med Chem. 1998 Nov 19; 41(24):4755-66. PMID: 9822546.
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    149. Ross DA, Magor BG, Middleton DL, Wilson MR, Miller NW, Clem LW, Warr GW. Characterization of Oct2 from the channel catfish: functional preference for a variant octamer motif. J Immunol. 1998 Apr 15; 160(8):3874-82. PMID: 9558093.
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    150. Nieusma JL, Claffey DJ, Koop DR, Chen W, Peter RM, Nelson SD, Ruth JA, Ross D. Oxidation of 1,3-butadiene to (R)- and (S)-butadiene monoxide by purified recombinant cytochrome P450 2E1 from rabbit, rat and human. Toxicol Lett. 1998 Mar 31; 95(2):123-9. PMID: 9635416.
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    151. Beall HD, Hudnott AR, Winski S, Siegel D, Swann E, Ross D, Moody CJ. Indolequinone antitumor agents: relationship between quinone structure and rate of metabolism by recombinant human NQO1. Bioorg Med Chem Lett. 1998 Mar 03; 8(5):545-8. PMID: 9871615.
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    152. Geatch DR, Ross DA, Heasman PA, Taylor JJ. Expression of T-cell receptor Vbeta2, 6 and 8 gene families in chronic adult periodontal disease. Eur J Oral Sci. 1997 Oct; 105(5 Pt 1):397-404. PMID: 9395100.
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    153. Siegel D, Bolton EM, Burr JA, Liebler DC, Ross D. The reduction of alpha-tocopherolquinone by human NAD(P)H: quinone oxidoreductase: the role of alpha-tocopherolhydroquinone as a cellular antioxidant. Mol Pharmacol. 1997 Aug; 52(2):300-5. PMID: 9271353.
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    154. Rothman N, Smith MT, Hayes RB, Traver RD, Hoener B, Campleman S, Li GL, Dosemeci M, Linet M, Zhang L, Xi L, Wacholder S, Lu W, Meyer KB, Titenko-Holland N, Stewart JT, Yin S, Ross D. Benzene poisoning, a risk factor for hematological malignancy, is associated with the NQO1 609C-->T mutation and rapid fractional excretion of chlorzoxazone. Cancer Res. 1997 Jul 15; 57(14):2839-42. PMID: 9230185.
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    155. Lei XG, Ross DA, Roneker KR. Comparison of age-related differences in expression of phospholipid hydroperoxide glutathione peroxidase mRNA and activity in various tissues of pigs. Comp Biochem Physiol B Biochem Mol Biol. 1997 May; 117(1):109-14. PMID: 9180019.
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    156. Nieusma JL, Claffey DJ, Maniglier-Poulet C, Imiolczyk T, Ross D, Ruth JA. Stereochemical aspects of 1,3-butadiene metabolism and toxicity in rat and mouse liver microsomes and freshly isolated rat hepatocytes. Chem Res Toxicol. 1997 Apr; 10(4):450-6. PMID: 9114983.
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    157. Ross D, Siegel D, Schattenberg DG, Sun XM, Moran JL. Cell-specific activation and detoxification of benzene metabolites in mouse and human bone marrow: identification of target cells and a potential role for modulation of apoptosis in benzene toxicity. Environ Health Perspect. 1996 Dec; 104 Suppl 6:1177-82. PMID: 9118890.
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    158. Gustafson DL, Beall HD, Bolton EM, Ross D, Waldren CA. Expression of human NAD(P)H: quinone oxidoreductase (DT-diaphorase) in Chinese hamster ovary cells: effect on the toxicity of antitumor quinones. Mol Pharmacol. 1996 Oct; 50(4):728-35. PMID: 8863816.
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    159. Moran JL, Siegel D, Sun XM, Ross D. Induction of apoptosis by benzene metabolites in HL60 and CD34+ human bone marrow progenitor cells. Mol Pharmacol. 1996 Sep; 50(3):610-5. PMID: 8794901.
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    160. Kimmelman AC, Ross DA, Liang BC. Loss of heterozygosity of chromosome 10p in human gliomas. Genomics. 1996 Jun 01; 34(2):250-4. PMID: 8661060.
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    161. Ross D. Metabolic basis of benzene toxicity. Eur J Haematol Suppl. 1996; 60:111-8. PMID: 8987252.
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    162. Maniglier-Poulet C, Cheng X, Ruth JA, Ross D. Metabolism of 1,3-butadiene to butadiene monoxide in mouse and human bone marrow cells. Chem Biol Interact. 1995 Jul 14; 97(2):119-29. PMID: 7606811.
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    163. Wilson GD, Richman PI, Dische S, Saunders MI, Robinson B, Daley FM, Ross DA. p53 status of head and neck cancer: relation to biological characteristics and outcome of radiotherapy. Br J Cancer. 1995 Jun; 71(6):1248-52. PMID: 7779719.
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    164. Miller AC, Schattenberg DG, Malkinson AM, Ross D. Decreased content of the IL1 alpha processing enzyme calpain in murine bone marrow-derived macrophages after treatment with the benzene metabolite hydroquinone. Toxicol Lett. 1994 Nov; 74(2):177-84. PMID: 7940599.
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    165. Schattenberg DG, Stillman WS, Gruntmeir JJ, Helm KM, Irons RD, Ross D. Peroxidase activity in murine and human hematopoietic progenitor cells: potential relevance to benzene-induced toxicity. Mol Pharmacol. 1994 Aug; 46(2):346-51. PMID: 8078496.
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    166. Cheng X, Maniglier-Poulet C, Ross D, Ruth JA. Solvolytic formation of 1,2-dichloro-3,4-epoxybutane from butadiene monoxide under physiological conditions. Drug Metab Dispos. 1994 Mar-Apr; 22(2):206-10. PMID: 8013275.
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    167. Goon D, Matsuura J, Ross D. Metabolism and cytotoxicity of trans,trans-muconaldehyde and its derivatives: potential markers of benzene ring cleavage reactions. Chem Biol Interact. 1993 Jul; 88(1):37-53. PMID: 8330323.
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    168. Goon D, Saxena M, Awasthi YC, Ross D. Activity of mouse liver glutathione S-transferases toward trans,trans-muconaldehyde and trans-4-hydroxy-2-nonenal. Toxicol Appl Pharmacol. 1993 Apr; 119(2):175-80. PMID: 8480327.
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    169. Gibson NW, Ross D. Mitomycin C. Cancer Chemother Biol Response Modif. 1993; 14:45-54. PMID: 8312113.
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    170. Ganousis LG, Goon D, Zyglewska T, Wu KK, Ross D. Cell-specific metabolism in mouse bone marrow stroma: studies of activation and detoxification of benzene metabolites. Mol Pharmacol. 1992 Dec; 42(6):1118-25. PMID: 1480134.
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    171. Goon D, Cheng X, Ruth JA, Petersen DR, Ross D. Metabolism of trans,trans-muconaldehyde by aldehyde and alcohol dehydrogenases: identification of a novel metabolite. Toxicol Appl Pharmacol. 1992 May; 114(1):147-55. PMID: 1585367.
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    172. Ross DA, Norman D, Wilson CB. Radiologic characteristics and results of surgical management of Rathke's cysts in 43 patients. Neurosurgery. 1992 Feb; 30(2):173-8; discussion 178-9. PMID: 1545884.
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    173. Ross DA, Drasner K, Weinstein PR, Flaherty JF, Barbaro NM. Use of intrathecally administered morphine in the treatment of postoperative pain after lumbar spinal surgery: a prospective, double-blind, placebo-controlled study. Neurosurgery. 1991 May; 28(5):700-4. PMID: 1876247.
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    174. Kalia KK, Ross DA, Gutin PH. Multiple arterial fenestrations, multiple aneurysms, and an arteriovenous malformation in a patient with subarachnoid hemorrhage. Surg Neurol. 1991 Jan; 35(1):45-8. PMID: 1983881.
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    175. Thomas DJ, Sadler A, Subrahmanyam VV, Siegel D, Reasor MJ, Wierda D, Ross D. Bone marrow stromal cell bioactivation and detoxification of the benzene metabolite hydroquinone: comparison of macrophages and fibroblastoid cells. Mol Pharmacol. 1990 Feb; 37(2):255-62. PMID: 2154673.
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    176. Ross D, Siegel D, Gibson NW, Pacheco D, Thomas DJ, Reasor M, Wierda D. Activation and deactivation of quinones catalyzed by DT-diaphorase. Evidence for bioreductive activation of diaziquone (AZQ) in human tumor cells and detoxification of benzene metabolites in bone marrow stroma. Free Radic Res Commun. 1990; 8(4-6):373-81. PMID: 2113030.
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    177. Ross DA, Olsen WL, Ross AM, Andrews BT, Pitts LH. Brain shift, level of consciousness, and restoration of consciousness in patients with acute intracranial hematoma. J Neurosurg. 1989 Oct; 71(4):498-502. PMID: 2795168.
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    178. Pue MA, Ransley JA, Writer DJ, Dean AJ, Franklin ER, Beattie IG, Ross DA. The disposition of SK&F L-94901, a selective thyromimetic in rat, dog and cynomolgus monkey. Eur J Drug Metab Pharmacokinet. 1989 Jul-Sep; 14(3):209-19. PMID: 2612518.
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    179. Ross DA, Wilson CB. Results of transsphenoidal microsurgery for growth hormone-secreting pituitary adenoma in a series of 214 patients. J Neurosurg. 1988 Jun; 68(6):854-67. PMID: 3373281.
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    180. Ross DA, Olsen WL, Halbach V, Rosegay H, Pitts LH. Cervical root compression by a traumatic pseudoaneurysm of the vertebral artery: case report. Neurosurgery. 1988 Feb; 22(2):414-7. PMID: 3352893.
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    181. Sandy MS, Moldeus P, Ross D, Smith MT. Cytotoxicity of the redox cycling compound diquat in isolated hepatocytes: involvement of hydrogen peroxide and transition metals. Arch Biochem Biophys. 1987 Nov 15; 259(1):29-37. PMID: 2825600.
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    182. Floeter MK, So YT, Ross DA, Greenberg D. Miliary metastasis to the brain: clinical and radiologic features. Neurology. 1987 Nov; 37(11):1817-8. PMID: 3670620.
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    183. Kirk LK, Lewis BA, Ross DA, Morrison MA. Identification of ninhydrin-positive caprolactam metabolites in the rat. Food Chem Toxicol. 1987 Mar; 25(3):233-9. PMID: 3570112.
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    184. Sandy MS, Moldeus P, Ross D, Smith MT. Role of redox cycling and lipid peroxidation in bipyridyl herbicide cytotoxicity. Studies with a compromised isolated hepatocyte model system. Biochem Pharmacol. 1986 Sep 15; 35(18):3095-101. PMID: 3019355.
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    185. Porubek D, Rundgren M, Larsson R, Albano E, Ross D, Nelson SD, Moldéus P. Quinone imines as biological reactive intermediates. Adv Exp Med Biol. 1986; 197:631-44. PMID: 3766286.
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    186. Ross D, Moldeus P. Thiyl radicals--their generation and further reactions. Adv Exp Med Biol. 1986; 197:329-35. PMID: 3020933.
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    187. Ross D, Mehlhorn RJ, Moldeus P, Smith MT. Metabolism of diethylstilbestrol by horseradish peroxidase and prostaglandin synthase--evidence for a free radical intermediate. Adv Exp Med Biol. 1986; 197:323-8. PMID: 3020932.
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    188. Ross D, Mehlhorn RJ, Moldeus P, Smith MT. Metabolism of diethylstilbestrol by horseradish peroxidase and prostaglandin-H synthase. Generation of a free radical intermediate and its interaction with glutathione. J Biol Chem. 1985 Dec 25; 260(30):16210-4. PMID: 2999150.
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    189. Ross D, Norbeck K, Moldéus P. The generation and subsequent fate of glutathionyl radicals in biological systems. J Biol Chem. 1985 Dec 05; 260(28):15028-32. PMID: 2999101.
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    190. Ross D, Moldeus P. Generation of reactive species and fate of thiols during peroxidase-catalyzed metabolic activation of aromatic amines and phenols. Environ Health Perspect. 1985 Dec; 64:253-7. PMID: 3007092.
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    191. Larsson R, Ross D, Berlin T, Olsson LI, Moldéus P. Prostaglandin synthase catalyzed metabolic activation of p-phenetidine and acetaminophen by microsomes isolated from rabbit and human kidney. J Pharmacol Exp Ther. 1985 Nov; 235(2):475-80. PMID: 3932643.
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    192. Moldéus P, Ross D, Larsson R. Co-oxidation of xenobiotics. Biochem Soc Trans. 1985 Oct; 13(5):847-50. PMID: 3934012.
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    193. Ross D, Thor H, Orrenius S, Moldeus P. Interaction of menadione (2-methyl-1,4-naphthoquinone) with glutathione. Chem Biol Interact. 1985 Oct; 55(1-2):177-84. PMID: 2998631.
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    194. Ohno Y, Ormstad K, Ross D, Orrenius S. Mechanism of allyl alcohol toxicity and protective effects of low-molecular-weight thiols studied with isolated rat hepatocytes. Toxicol Appl Pharmacol. 1985 Apr; 78(2):169-79. PMID: 2930914.
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    195. Ross D, Larsson R, Norbeck K, Ryhage R, Moldéus P. Characterization and mechanism of formation of reactive products formed during peroxidase-catalyzed oxidation of p-phenetidine. Trapping of reactive species by reduced glutathione and butylated hydroxyanisole. Mol Pharmacol. 1985 Feb; 27(2):277-86. PMID: 3969071.
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    196. Ross D, Larsson R, Andersson B, Nilsson U, Lindquist T, Lindeke B, Moldéus P. The oxidation of p-phenetidine by horseradish peroxidase and prostaglandin synthase and the fate of glutathione during such oxidations. Biochem Pharmacol. 1985 Feb 01; 34(3):343-51. PMID: 2982385.
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    197. Di Monte D, Ross D, Bellomo G, Eklöw L, Orrenius S. Alterations in intracellular thiol homeostasis during the metabolism of menadione by isolated rat hepatocytes. Arch Biochem Biophys. 1984 Dec; 235(2):334-42. PMID: 6097182.
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    198. Larsson R, Ross D, Nordenskjöld M, Lindeke B, Olsson LI, Moldéus P. Reactive products formed by peroxidase catalyzed oxidation of p-phenetidine. Chem Biol Interact. 1984 Nov; 52(1):1-14. PMID: 6499076.
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    199. Moldéus P, Larsson R, Ross D, Andersson B. Peroxidase-catalysed metabolism of drugs and carcinogens. Biochem Soc Trans. 1984 Feb; 12(1):20-3. PMID: 6423419.
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    200. Harkrader RJ, Jackson RC, Ross DA, Weber G. Increase in liver and kidney deoxycytidine kinase activity linked to neoplastic transformation. Biochem Biophys Res Commun. 1980 Oct 31; 96(4):1633-9. PMID: 6255949.
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