Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Robert Carl Murphy

TitleProfessor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM - Pharmacology
Phone303/724-3352
    Other Positions
    TitleDistinguished Professor
    InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
    DepartmentSOM - Pharmacology


    Collapse Research 
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    T32GM007635     (THORBURN, ANDREW M)Jul 1, 1978 - Jun 30, 2019
    NIH/NIGMS
    Predoctoral Training Grant in Pharmacology
    Role: Co-Principal Investigator

    R37HL025785     (MURPHY, ROBERT CARL)Apr 1, 1980 - Mar 31, 1998
    NIH/NHLBI
    LEUKOTRIENES AND SLOW REACTING SUBSTANCE OF ANAPHYLAXIS
    Role: Principal Investigator

    R01HL025785     (MURPHY, ROBERT CARL)Apr 1, 1980 - Jan 31, 2013
    NIH/NHLBI
    Leukotrienes and Slow Reacting Substance of Anaphylaxis
    Role: Principal Investigator

    R01AI020774     (MURPHY, ROBERT CARL)Jan 1, 1984 - Dec 31, 1989
    NIH/NIAID
    LEUKOTRIENES AND PLATELET ACTIVATING FACTOR
    Role: Principal Investigator

    P01HL034303     (LESLIE, CHRISTINA CARROLL)Sep 30, 1985 - Jan 31, 2016
    NIH/NHLBI
    Ether Lipids, Elcosanoids, and Lung Cell Pathophysiology
    Role: Co-Principal Investigator

    S10RR009110     (MURPHY, ROBERT CARL)May 18, 1994 - May 17, 1995
    NIH/NCRR
    ELECTROSPRAY TANDEM MASS SPECTROMETER
    Role: Principal Investigator

    R01AA009468     (MURPHY, ROBERT CARL)Apr 1, 1996 - Mar 31, 1999
    NIH/NIAAA
    NEUTROPHIL CHEMOTACTIC FACTOR AND ALCOHOLIC HEPATITIS
    Role: Principal Investigator

    R13HL057774     (MURPHY, ROBERT CARL)Feb 1, 1997 - Jan 31, 1998
    NIH/NHLBI
    CONFERENCE ON LIPID MEDIATORS
    Role: Principal Investigator

    R01HL064030     (MURPHY, ROBERT CARL)Feb 10, 2001 - Jun 30, 2001
    NIH/NHLBI
    EOSINOPHIL, EICOSANOID, BIOSYNTHESIS AND METABOLISM
    Role: Principal Investigator

    S10RR027216     (MURPHY, ROBERT CARL)Aug 1, 2010 - Jul 31, 2011
    NIH/NCRR
    Lipid Tandem Quadrupole Mass Spectrometer
    Role: Principal Investigator

    R01ES022172     (MURPHY, ROBERT CARL)Sep 15, 2012 - Jun 30, 2017
    NIH/NIEHS
    High Throughput Lipidomics Analysis by MALDI/Ion Mobility Mass Spectrometry
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Hawkins C, Christian B, Fabian E, Macha I, Gawile C, Mpangala S, Ulenga N, Thio CL, Ammerman LR, Mugusi F, Fawzi W, Green R, Murphy R. Brief Report: HIV/HBV Coinfection is a Significant Risk Factor for Liver Fibrosis in Tanzanian HIV-Infected Adults. J Acquir Immune Defic Syndr. 2017 Nov 01; 76(3):298-302. PMID: 29016448.
      View in: PubMed
    2. Sorgi CA, Zarini S, Martin SA, Sanchez RL, Scandiuzzi RF, Gijón MA, Guijas C, Flamand N, Murphy RC, Faccioli LH. Dormant 5-lipoxygenase in inflammatory macrophages is triggered by exogenous arachidonic acid. Sci Rep. 2017 Sep 08; 7(1):10981. PMID: 28887514.
      View in: PubMed
    3. Murphy RC, Okuno T, Johnson CA, Barkley RM. Determination of Double Bond Positions in Polyunsaturated Fatty Acids Using the Photochemical Paternò-Büchi Reaction with Acetone and Tandem Mass Spectrometry. Anal Chem. 2017 Aug 15; 89(16):8545-8553. PMID: 28719189.
      View in: PubMed
    4. Hawkins C, Christian B, Fabian E, Macha I, Gawile C, Mpangala S, Ulenga N, Thio CL, Rose Ammerman L, Mugusi F, Fawzi W, Green R, Murphy R. HIV/HBV co-infection is a significant risk factor for liver fibrosis in Tanzanian HIV-infected adults. J Acquir Immune Defic Syndr. 2017 Jun 22. PMID: 28650402.
      View in: PubMed
    5. Muchenditsi A, Yang H, Hamilton JP, Koganti L, Housseau F, Aronov L, Fan H, Pierson H, Bhattacharjee A, Murphy R, Sears C, Potter J, Wooton-Kee CR, Lutsenko S. Targeted inactivation of copper transporter Atp7b in hepatocytes causes liver steatosis and obesity in mice. Am J Physiol Gastrointest Liver Physiol. 2017 Jul 01; 313(1):G39-G49. PMID: 28428350.
      View in: PubMed
    6. Zemski Berry KA, Murphy RC, Kosmider B, Mason RJ. Lipidomic characterization and localization of phospholipids in the human lung. J Lipid Res. 2017 May; 58(5):926-933. PMID: 28280112.
      View in: PubMed
    7. Turcotte C, Zarini S, Jean S, Martin C, Murphy RC, Marsolais D, Laviolette M, Blanchet MR, Flamand N. The Endocannabinoid Metabolite Prostaglandin E2 (PGE2)-Glycerol Inhibits Human Neutrophil Functions: Involvement of Its Hydrolysis into PGE2 and EP Receptors. J Immunol. 2017 Apr 15; 198(8):3255-3263. PMID: 28258202.
      View in: PubMed
    8. O'Donnell VB, Murphy RC. Directing eicosanoid esterification into phospholipids. J Lipid Res. 2017 May; 58(5):837-839. PMID: 28242788.
      View in: PubMed
    9. Aldrovandi M, Hinz C, Lauder SN, Podmore H, Hornshaw M, Slatter DA, Tyrrell VJ, Clark SR, Marnett LJ, Collins PW, Murphy RC, O'Donnell VB. DioxolaneA3-phosphatidylethanolamines are generated by human platelets and stimulate neutrophil integrin expression. Redox Biol. 2017 Apr; 11:663-672. PMID: 28160743.
      View in: PubMed
    10. Fickes R, Voelker DR, Berry KZ, Murphy RC. Tandem mass spectrometry of novel ether-linked phospholipid analogs of anionic pulmonary surfactant phospholipids. Rapid Commun Mass Spectrom. 2016 Dec 30; 30(24):2601-2606. PMID: 27689848.
      View in: PubMed
    11. Berry KA, Barkley RM, Berry JJ, Hankin JA, Hoyes E, Brown JM, Murphy RC. Tandem Mass Spectrometry in Combination with Product Ion Mobility for the Identification of Phospholipids. Anal Chem. 2017 Jan 03; 89(1):916-921. PMID: 27958700.
      View in: PubMed
    12. Axelsen PH, Murphy RC, Igarashi M, Rapoport SI. Increased ?6-Containing Phospholipids and Primary ?6 Oxidation Products in the Brain Tissue of Rats on an ?3-Deficient Diet. PLoS One. 2016; 11(10):e0164326. PMID: 27788153.
      View in: PubMed
    13. Jayaraja S, Dakhama A, Yun B, Ghosh M, Lee H, Redente EF, Uhlson CL, Murphy RC, Leslie CC. Cytosolic phospholipase A2 contributes to innate immune defense against Candida albicans lung infection. BMC Immunol. 2016 Aug 08; 17(1):27. PMID: 27501951; PMCID: PMC4977843.
    14. Zemski Berry KA, Murphy RC. Phospholipid Ozonation Products Activate the 5-Lipoxygenase Pathway in Macrophages. Chem Res Toxicol. 2016 Aug 15; 29(8):1355-64. PMID: 27448436.
      View in: PubMed
    15. Chen Y, Singh S, Matsumoto A, Manna SK, Abdelmegeed MA, Golla S, Murphy RC, Dong H, Song BJ, Gonzalez FJ, Thompson DC, Vasiliou V. Chronic Glutathione Depletion Confers Protection against Alcohol-induced Steatosis: Implication for Redox Activation of AMP-activated Protein Kinase Pathway. Sci Rep. 2016 Jul 12; 6:29743. PMID: 27403993; PMCID: PMC4940737.
    16. Hankin JA, Barkley RM, Zemski-Berry K, Deng Y, Murphy RC. Mass Spectrometric Collisional Activation and Product Ion Mobility of Human Serum Neutral Lipid Extracts. Anal Chem. 2016 Jun 21; 88(12):6274-82. PMID: 27213895; PMCID: PMC5007945.
    17. Martin SA, Brash AR, Murphy RC. The discovery and early structural studies of arachidonic acid. J Lipid Res. 2016 Jul; 57(7):1126-32. PMID: 27142391; PMCID: PMC4918860 [Available on 07/01/17].
    18. Lehman VT, Murphy RC, Schenck LA, Carter RE, Johnson GB, Kotsenas AL, Morris JM, Nathan MA, Wald JT, Maus TP. Comparison of facet joint activity on 99mTc-MDP SPECT/CT with facet joint signal change on MRI with fat suppression. Diagn Interv Radiol. 2016 May-Jun; 22(3):277-83. PMID: 27035592; PMCID: PMC4859746.
    19. Slatter DA, Aldrovandi M, O'Connor A, Allen SM, Brasher CJ, Murphy RC, Mecklemann S, Ravi S, Darley-Usmar V, O'Donnell VB. Mapping the Human Platelet Lipidome Reveals Cytosolic Phospholipase A2 as a Regulator of Mitochondrial Bioenergetics during Activation. Cell Metab. 2016 May 10; 23(5):930-44. PMID: 27133131; PMCID: PMC4873619.
    20. Hinz C, Aldrovandi M, Uhlson C, Marnett LJ, Longhurst HJ, Warner TD, Alam S, Slatter DA, Lauder SN, Allen-Redpath K, Collins PW, Murphy RC, Thomas CP, O'Donnell VB. Human Platelets Utilize Cycloxygenase-1 to Generate Dioxolane A3, a Neutrophil-activating Eicosanoid. J Biol Chem. 2016 Jun 24; 291(26):13448-64. PMID: 27129261; PMCID: PMC4919433.
    21. Kandasamy P, Numata M, Berry KZ, Fickes R, Leslie CC, Murphy RC, Voelker DR. Structural analogs of pulmonary surfactant phosphatidylglycerol inhibit toll-like receptor 2 and 4 signaling. J Lipid Res. 2016 Jun; 57(6):993-1005. PMID: 27095543; PMCID: PMC4878184 [Available on 06/01/17].
    22. Sahu RP, Harrison KA, Weyerbacher J, Murphy RC, Konger RL, Garrett JE, Chin-Sinex HJ, Johnston ME, Dynlacht JR, Mendonca M, McMullen K, Li G, Spandau DF, Travers JB. Radiation therapy generates platelet-activating factor agonists. Oncotarget. 2016 Apr 12; 7(15):20788-800. PMID: 26959112; PMCID: PMC4991492.
    23. Dong L, Zou H, Yuan C, Hong YH, Uhlson CL, Murphy RC, Smith WL. Interactions of 2-O-arachidonylglycerol ether and ibuprofen with the allosteric and catalytic subunits of human COX-2. J Lipid Res. 2016 Jun; 57(6):1043-50. PMID: 27059979; PMCID: PMC4878188 [Available on 06/01/17].
    24. Hamilton JP, Koganti L, Muchenditsi A, Pendyala VS, Huso D, Hankin J, Murphy RC, Huster D, Merle U, Mangels C, Yang N, Potter JJ, Mezey E, Lutsenko S. Activation of liver X receptor/retinoid X receptor pathway ameliorates liver disease in Atp7B(-/-) (Wilson disease) mice. Hepatology. 2016 Jun; 63(6):1828-41. PMID: 26679751; PMCID: PMC4874878 [Available on 06/01/17].
    25. Yun B, Lee H, Jayaraja S, Suram S, Murphy RC, Leslie CC. Prostaglandins from Cytosolic Phospholipase A2a/Cyclooxygenase-1 Pathway and Mitogen-activated Protein Kinases Regulate Gene Expression in Candida albicans-infected Macrophages. J Biol Chem. 2016 Mar 25; 291(13):7070-86. PMID: 26841868; PMCID: PMC4807289 [Available on 03/25/17].
    26. Welle CL, Cullen EL, Peller PJ, Lowe VJ, Murphy RC, Johnson GB, Binkovitz LA. ¹¹C-Choline PET/CT in Recurrent Prostate Cancer and Nonprostatic Neoplastic Processes. Radiographics. 2016 Jan-Feb; 36(1):279-92. PMID: 26761541.
      View in: PubMed
    27. Poczobutt JM, Nguyen TT, Hanson D, Li H, Sippel TR, Weiser-Evans MC, Gijon M, Murphy RC, Nemenoff RA. Deletion of 5-Lipoxygenase in the Tumor Microenvironment Promotes Lung Cancer Progression and Metastasis through Regulating T Cell Recruitment. J Immunol. 2016 Jan 15; 196(2):891-901. PMID: 26663781; PMCID: PMC4705594.
    28. Zolotor AJ, Runyan DK, Shanahan M, Durrance CP, Nocera M, Sullivan K, Klevens J, Murphy R, Barr M, Barr RG. Effectiveness of a Statewide Abusive Head Trauma Prevention Program in North Carolina. JAMA Pediatr. 2015 Dec; 169(12):1126-31. PMID: 26501945; PMCID: PMC4687484 [Available on 12/01/16].
    29. Murphy RC. Specialized pro-resolving mediators: do they circulate in plasma? J Lipid Res. 2015 Sep; 56(9):1641-2. PMID: 26232500; PMCID: PMC4548769.
    30. Grevengoed TJ, Martin SA, Katunga L, Cooper DE, Anderson EJ, Murphy RC, Coleman RA. Acyl-CoA synthetase 1 deficiency alters cardiolipin species and impairs mitochondrial function. J Lipid Res. 2015 Aug; 56(8):1572-82. PMID: 26136511; PMCID: PMC4513998.
    31. Shewale SV, Boudyguina E, Zhu X, Shen L, Hutchins PM, Barkley RM, Murphy RC, Parks JS. Botanical oils enriched in n-6 and n-3 FADS2 products are equally effective in preventing atherosclerosis and fatty liver. J Lipid Res. 2015 Jun; 56(6):1191-205. PMID: 25921305; PMCID: PMC4442876.
    32. Ito Y, Correll K, Zemans RL, Leslie CC, Murphy RC, Mason RJ. Influenza induces IL-8 and GM-CSF secretion by human alveolar epithelial cells through HGF/c-Met and TGF-a/EGFR signaling. Am J Physiol Lung Cell Mol Physiol. 2015 Jun 01; 308(11):L1178-88. PMID: 26033355; PMCID: PMC4451400.
    33. Li X, Ballantyne LL, Che X, Mewburn JD, Kang JX, Barkley RM, Murphy RC, Yu Y, Funk CD. Endogenously generated omega-3 fatty acids attenuate vascular inflammation and neointimal hyperplasia by interaction with free fatty acid receptor 4 in mice. J Am Heart Assoc. 2015 Apr 06; 4(4). PMID: 25845931; PMCID: PMC4579939.
    34. Almstrand AC, Johnson C, Murphy RC. Evidence for an N-methyl transfer reaction in phosphatidylcholines with a terminal aldehyde during negative electrospray ionization tandem mass spectrometry. Anal Bioanal Chem. 2015 Jul; 407(17):5045-52. PMID: 25736244.
      View in: PubMed
    35. Hankin JA, Murphy RC, Barkley RM, Gijón MA. Ion Mobility and Tandem Mass Spectrometry of Phosphatidylglycerol and Bis(monoacylglycerol)phosphate (BMP). Int J Mass Spectrom. 2015 Feb 15; 378:255-263. PMID: 25883529.
      View in: PubMed
    36. Wooding KM, Hankin JA, Johnson CA, Chosich JD, Baek SW, Bradford AP, Murphy RC, Santoro N. Measurement of estradiol, estrone, and testosterone in postmenopausal human serum by isotope dilution liquid chromatography tandem mass spectrometry without derivatization. Steroids. 2015 Apr; 96:89-94. PMID: 25617740; PMCID: PMC4366052.
    37. Gorden DL, Myers DS, Ivanova PT, Fahy E, Maurya MR, Gupta S, Min J, Spann NJ, McDonald JG, Kelly SL, Duan J, Sullards MC, Leiker TJ, Barkley RM, Quehenberger O, Armando AM, Milne SB, Mathews TP, Armstrong MD, Li C, Melvin WV, Clements RH, Washington MK, Mendonsa AM, Witztum JL, Guan Z, Glass CK, Murphy RC, Dennis EA, Merrill AH, Russell DW, Subramaniam S, Brown HA. Biomarkers of NAFLD progression: a lipidomics approach to an epidemic. J Lipid Res. 2015 Mar; 56(3):722-36. PMID: 25598080; PMCID: PMC4340319.
    38. Almstrand AC, Voelker D, Murphy RC. Identification of oxidized phospholipids in bronchoalveolar lavage exposed to low ozone levels using multivariate analysis. Anal Biochem. 2015 Apr 01; 474:50-8. PMID: 25575758; PMCID: PMC4375957.
    39. Numata M, Kandasamy P, Nagashima Y, Fickes R, Murphy RC, Voelker DR. Phosphatidylinositol inhibits respiratory syncytial virus infection. J Lipid Res. 2015 Mar; 56(3):578-87. PMID: 25561461; PMCID: PMC4340305.
    40. Portillo JA, Schwartz I, Zarini S, Bapputty R, Kern TS, Gubitosi-Klug RA, Murphy RC, Subauste MC, Subauste CS. Proinflammatory responses induced by CD40 in retinal endothelial and Müller cells are inhibited by blocking CD40-Traf2,3 or CD40-Traf6 signaling. Invest Ophthalmol Vis Sci. 2014 Dec 04; 55(12):8590-7. PMID: 25477319; PMCID: PMC4280881.
    41. Goldfeld DA, Murphy R, Kim B, Wang L, Beuming T, Abel R, Friesner RA. Docking and free energy perturbation studies of ligand binding in the kappa opioid receptor. J Phys Chem B. 2015 Jan 22; 119(3):824-35. PMID: 25395044.
      View in: PubMed
    42. García-Mateo N, Ganfornina MD, Montero O, Gijón MA, Murphy RC, Sanchez D. Schwann cell-derived Apolipoprotein D controls the dynamics of post-injury myelin recognition and degradation. Front Cell Neurosci. 2014; 8:374. PMID: 25426024; PMCID: PMC4227524.
    43. Crush AB, Howe BM, Spinner RJ, Amrami KK, Hunt CH, Johnson GB, Murphy RC, Morreale RF, Peller PJ. Malignant involvement of the peripheral nervous system in patients with cancer: multimodality imaging and pathologic correlation. Radiographics. 2014 Nov-Dec; 34(7):1987-2007. PMID: 25384297.
      View in: PubMed
    44. Montrose DC, Nakanishi M, Murphy RC, Zarini S, McAleer JP, Vella AT, Rosenberg DW. The role of PGE2 in intestinal inflammation and tumorigenesis. Prostaglandins Other Lipid Mediat. 2015 Jan-Mar; 116-117:26-36. PMID: 25460828; PMCID: PMC4385488.
    45. Sahu RP, Ocana JA, Harrison KA, Ferracini M, Touloukian CE, Al-Hassani M, Sun L, Loesch M, Murphy RC, Althouse SK, Perkins SM, Speicher PJ, Tyler DS, Konger RL, Travers JB. Chemotherapeutic agents subvert tumor immunity by generating agonists of platelet-activating factor. Cancer Res. 2014 Dec 01; 74(23):7069-78. PMID: 25304264; PMCID: PMC4252249.
    46. Capra V, Rovati GE, Mangano P, Buccellati C, Murphy RC, Sala A. Transcellular biosynthesis of eicosanoid lipid mediators. Biochim Biophys Acta. 2015 Apr; 1851(4):377-82. PMID: 25218301.
      View in: PubMed
    47. Ning F, Wang C, Berry KZ, Kandasamy P, Liu H, Murphy RC, Voelker DR, Nho CW, Pan CH, Dai S, Niu L, Chu HW, Zhang G. Structural characterization of the pulmonary innate immune protein SPLUNC1 and identification of lipid ligands. FASEB J. 2014 Dec; 28(12):5349-60. PMID: 25223608; PMCID: PMC4232288.
    48. Zarini S, Hankin JA, Murphy RC, Gijón MA. Lysophospholipid acyltransferases and eicosanoid biosynthesis in zebrafish myeloid cells. Prostaglandins Other Lipid Mediat. 2014 Oct; 113-115:52-61. PMID: 25175316; PMCID: PMC4252513.
    49. Jiang Y, Djuric Z, Sen A, Ren J, Kuklev D, Waters I, Zhao L, Uhlson CL, Hong YH, Murphy RC, Normolle DP, Smith WL, Brenner DE. Biomarkers for personalizing omega-3 fatty acid dosing. Cancer Prev Res (Phila). 2014 Oct; 7(10):1011-22. PMID: 25139294; PMCID: PMC4185239.
    50. Ferracini M, Sahu RP, Harrison KA, Waeiss RA, Murphy RC, Jancar S, Konger RL, Travers JB. Topical photodynamic therapy induces systemic immunosuppression via generation of platelet-activating factor receptor ligands. J Invest Dermatol. 2015 Jan; 135(1):321-323. PMID: 25050596; PMCID: PMC4268233.
    51. Shanahan M, Fleming P, Nocera M, Sullivan K, Murphy R, Zolotor A. Process evaluation of a statewide abusive head trauma prevention program. Eval Program Plann. 2014 Dec; 47:18-25. PMID: 25084513.
      View in: PubMed
    52. Hester AG, Murphy RC, Uhlson CJ, Ivester P, Lee TC, Sergeant S, Miller LR, Howard TD, Mathias RA, Chilton FH. Relationship between a common variant in the fatty acid desaturase (FADS) cluster and eicosanoid generation in humans. J Biol Chem. 2014 Aug 08; 289(32):22482-9. PMID: 24962583; PMCID: PMC4139254.
    53. Chilton FH, Murphy RC, Wilson BA, Sergeant S, Ainsworth H, Seeds MC, Mathias RA. Diet-gene interactions and PUFA metabolism: a potential contributor to health disparities and human diseases. Nutrients. 2014 May 21; 6(5):1993-2022. PMID: 24853887; PMCID: PMC4042578.
    54. O'Donnell VB, Murphy RC, Watson SP. Platelet lipidomics: modern day perspective on lipid discovery and characterization in platelets. Circ Res. 2014 Mar 28; 114(7):1185-203. PMID: 24677238; PMCID: PMC4021279.
    55. Corser-Jensen CE, Goodell DJ, Freund RK, Serbedzija P, Murphy RC, Farias SE, Dell'Acqua ML, Frey LC, Serkova N, Heidenreich KA. Blocking leukotriene synthesis attenuates the pathophysiology of traumatic brain injury and associated cognitive deficits. Exp Neurol. 2014 Jun; 256:7-16. PMID: 24681156; PMCID: PMC4731038.
    56. Ravandi A, Leibundgut G, Hung MY, Patel M, Hutchins PM, Murphy RC, Prasad A, Mahmud E, Miller YI, Dennis EA, Witztum JL, Tsimikas S. Release and capture of bioactive oxidized phospholipids and oxidized cholesteryl esters during percutaneous coronary and peripheral arterial interventions in humans. J Am Coll Cardiol. 2014 May 20; 63(19):1961-71. PMID: 24613321; PMCID: PMC4629781.
    57. Martin SA, Gijón MA, Voelker DR, Murphy RC. Measurement of lysophospholipid acyltransferase activities using substrate competition. J Lipid Res. 2014 Apr; 55(4):782-91. PMID: 24563510; PMCID: PMC3966712.
    58. Namgaladze D, Lips S, Leiker TJ, Murphy RC, Ekroos K, Ferreiros N, Geisslinger G, Brüne B. Inhibition of macrophage fatty acid ß-oxidation exacerbates palmitate-induced inflammatory and endoplasmic reticulum stress responses. Diabetologia. 2014 May; 57(5):1067-77. PMID: 24488024.
      View in: PubMed
    59. Kitajima K, Murphy RC, Nathan MA, Froemming AT, Hagen CE, Takahashi N, Kawashima A. Detection of recurrent prostate cancer after radical prostatectomy: comparison of 11C-choline PET/CT with pelvic multiparametric MR imaging with endorectal coil. J Nucl Med. 2014 Feb; 55(2):223-32. PMID: 24434294.
      View in: PubMed
    60. Ren J, Pei-Chen Lin C, Pathak MC, Temple BR, Nile AH, Mousley CJ, Duncan MC, Eckert DM, Leiker TJ, Ivanova PT, Myers DS, Murphy RC, Brown HA, Verdaasdonk J, Bloom KS, Ortlund EA, Neiman AM, Bankaitis VA. A phosphatidylinositol transfer protein integrates phosphoinositide signaling with lipid droplet metabolism to regulate a developmental program of nutrient stress-induced membrane biogenesis. Mol Biol Cell. 2014 Mar; 25(5):712-27. PMID: 24403601; PMCID: PMC3937096.
    61. Zemski Berry KA, Gordon WC, Murphy RC, Bazan NG. Spatial organization of lipids in the human retina and optic nerve by MALDI imaging mass spectrometry. J Lipid Res. 2014 Mar; 55(3):504-15. PMID: 24367044; PMCID: PMC3934734.
    62. Le CH, Mulligan CM, Routh MA, Bouma GJ, Frye MA, Jeckel KM, Sparagna GC, Lynch JM, Moore RL, McCune SA, Bristow M, Zarini S, Murphy RC, Chicco AJ. Delta-6-desaturase links polyunsaturated fatty acid metabolism with phospholipid remodeling and disease progression in heart failure. Circ Heart Fail. 2014 Jan; 7(1):172-83. PMID: 24284026.
      View in: PubMed
    63. Poczobutt JM, Gijon M, Amin J, Hanson D, Li H, Walker D, Weiser-Evans M, Lu X, Murphy RC, Nemenoff RA. Eicosanoid profiling in an orthotopic model of lung cancer progression by mass spectrometry demonstrates selective production of leukotrienes by inflammatory cells of the microenvironment. PLoS One. 2013; 8(11):e79633. PMID: 24244531; PMCID: PMC3823604.
    64. Shibata N, Carlin AF, Spann NJ, Saijo K, Morello CS, McDonald JG, Romanoski CE, Maurya MR, Kaikkonen MU, Lam MT, Crotti A, Reichart D, Fox JN, Quehenberger O, Raetz CR, Sullards MC, Murphy RC, Merrill AH, Brown HA, Dennis EA, Fahy E, Subramaniam S, Cavener DR, Spector DH, Russell DW, Glass CK. 25-Hydroxycholesterol activates the integrated stress response to reprogram transcription and translation in macrophages. J Biol Chem. 2013 Dec 13; 288(50):35812-23. PMID: 24189069; PMCID: PMC3861632.
    65. Lehman VT, Murphy RC, Maus TP. 99mTc-MDP SPECT/CT of the spine and sacrum at a multispecialty institution: clinical use, findings, and impact on patient management. Nucl Med Commun. 2013 Nov; 34(11):1097-106. PMID: 23942325.
      View in: PubMed
    66. Kitajima K, Murphy RC, Nathan MA, Sugimura K. Update on positron emission tomography for imaging of prostate cancer. Int J Urol. 2014 Jan; 21(1):12-23. PMID: 23991644.
      View in: PubMed
    67. Wooding KM, Barkley RM, Hankin JA, Johnson CA, Bradford AP, Santoro N, Murphy RC. Mechanism of formation of the major estradiol product ions following collisional activation of the molecular anion in a tandem quadrupole mass spectrometer. J Am Soc Mass Spectrom. 2013 Oct; 24(10):1451-5. PMID: 23955001; PMCID: PMC3786604.
    68. Suram S, Silveira LJ, Mahaffey S, Brown GD, Bonventre JV, Williams DL, Gow NA, Bratton DL, Murphy RC, Leslie CC. Cytosolic phospholipase A(2)a and eicosanoids regulate expression of genes in macrophages involved in host defense and inflammation. PLoS One. 2013; 8(7):e69002. PMID: 23950842; PMCID: PMC3742295.
    69. Aldrovandi M, Hammond VJ, Podmore H, Hornshaw M, Clark SR, Marnett LJ, Slatter DA, Murphy RC, Collins PW, O'Donnell VB. Human platelets generate phospholipid-esterified prostaglandins via cyclooxygenase-1 that are inhibited by low dose aspirin supplementation. J Lipid Res. 2013 Nov; 54(11):3085-97. PMID: 23883581; PMCID: PMC3793613.
    70. Brown TT, Chen Y, Currier JS, Ribaudo HJ, Rothenberg J, Dubé MP, Murphy R, Stein JH, McComsey GA. Body composition, soluble markers of inflammation, and bone mineral density in antiretroviral therapy-naive HIV-1-infected individuals. J Acquir Immune Defic Syndr. 2013 Jul 01; 63(3):323-30. PMID: 23591634; PMCID: PMC3693854.
    71. Maurya MR, Gupta S, Li X, Fahy E, Dinasarapu AR, Sud M, Brown HA, Glass CK, Murphy RC, Russell DW, Dennis EA, Subramaniam S. Analysis of inflammatory and lipid metabolic networks across RAW264.7 and thioglycolate-elicited macrophages. J Lipid Res. 2013 Sep; 54(9):2525-42. PMID: 23776196; PMCID: PMC3735949.
    72. Numata M, Nagashima Y, Moore ML, Berry KZ, Chan M, Kandasamy P, Peebles RS, Murphy RC, Voelker DR. Phosphatidylglycerol provides short-term prophylaxis against respiratory syncytial virus infection. J Lipid Res. 2013 Aug; 54(8):2133-43. PMID: 23749985; PMCID: PMC3708363.
    73. Kuklev DV, Hankin JA, Uhlson CL, Hong YH, Murphy RC, Smith WL. Major urinary metabolites of 6-keto-prostaglandin F2a in mice. J Lipid Res. 2013 Jul; 54(7):1906-14. PMID: 23644380; PMCID: PMC3679392.
    74. Maiga M, Ammerman NC, Maiga MC, Tounkara A, Siddiqui S, Polis M, Murphy R, Bishai WR. Adjuvant host-directed therapy with types 3 and 5 but not type 4 phosphodiesterase inhibitors shortens the duration of tuberculosis treatment. J Infect Dis. 2013 Aug 01; 208(3):512-9. PMID: 23641020; PMCID: PMC3699007.
    75. Kitajima K, Murphy RC, Nathan MA. Choline PET/CT for imaging prostate cancer: an update. Ann Nucl Med. 2013 Aug; 27(7):581-91. PMID: 23632880.
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    76. Clark SR, Thomas CP, Hammond VJ, Aldrovandi M, Wilkinson GW, Hart KW, Murphy RC, Collins PW, O'Donnell VB. Characterization of platelet aminophospholipid externalization reveals fatty acids as molecular determinants that regulate coagulation. Proc Natl Acad Sci U S A. 2013 Apr 09; 110(15):5875-80. PMID: 23530199; PMCID: PMC3625294.
    77. O'Toole O, Murphy R, Tracy JA, McKeon A. Teaching NeuroImages: PET-CT hypermetabolism paralleling muscle hyperactivity in stiff-person syndrome. Neurology. 2013 Mar 05; 80(10):e109. PMID: 23460625.
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    78. Cantley JL, Yoshimura T, Camporez JP, Zhang D, Jornayvaz FR, Kumashiro N, Guebre-Egziabher F, Jurczak MJ, Kahn M, Guigni BA, Serr J, Hankin J, Murphy RC, Cline GW, Bhanot S, Manchem VP, Brown JM, Samuel VT, Shulman GI. CGI-58 knockdown sequesters diacylglycerols in lipid droplets/ER-preventing diacylglycerol-mediated hepatic insulin resistance. Proc Natl Acad Sci U S A. 2013 Jan 29; 110(5):1869-74. PMID: 23302688; PMCID: PMC3562813.
    79. Rees ML, Gioscia-Ryan RA, McCune SA, Browder JC, Zachman DK, Chicco AJ, Johnson CA, Murphy RC, Moore RL, Sparagna GC. The AIN-76A defined rodent diet accelerates the development of heart failure in SHHF rats: a cautionary note on its use in cardiac studies. J Anim Physiol Anim Nutr (Berl). 2014 Feb; 98(1):56-64. PMID: 23298172.
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    80. Frasch SC, Fernandez-Boyanapalli RF, Berry KA, Murphy RC, Leslie CC, Nick JA, Henson PM, Bratton DL. Neutrophils regulate tissue Neutrophilia in inflammation via the oxidant-modified lipid lysophosphatidylserine. J Biol Chem. 2013 Feb 15; 288(7):4583-93. PMID: 23293064; PMCID: PMC3576064.
    81. Merrill AH, Murphy RC, Smith WL, Vance DE, Wilson JE, Yu RK. In memoriam: Charles (Chuck) Crawford Sweeley, Jr. (1930-2012). J Lipid Res. 2013 Jan; 54(1):1-4. PMID: 23367521; PMCID: PMC3520516.
    82. Talahalli R, Zarini S, Tang J, Li G, Murphy R, Kern TS, Gubitosi-Klug RA. Leukocytes regulate retinal capillary degeneration in the diabetic mouse via generation of leukotrienes. J Leukoc Biol. 2013 Jan; 93(1):135-43. PMID: 23108096; PMCID: PMC3525833.
    83. Spann NJ, Garmire LX, McDonald JG, Myers DS, Milne SB, Shibata N, Reichart D, Fox JN, Shaked I, Heudobler D, Raetz CR, Wang EW, Kelly SL, Sullards MC, Murphy RC, Merrill AH, Brown HA, Dennis EA, Li AC, Ley K, Tsimikas S, Fahy E, Subramaniam S, Quehenberger O, Russell DW, Glass CK. Regulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responses. Cell. 2012 Sep 28; 151(1):138-52. PMID: 23021221; PMCID: PMC3464914.
    84. Lehman VT, Carter RE, Claassen DO, Murphy RC, Lowe V, Petersen RC, Peller PJ. Visual assessment versus quantitative three-dimensional stereotactic surface projection fluorodeoxyglucose positron emission tomography for detection of mild cognitive impairment and Alzheimer disease. Clin Nucl Med. 2012 Aug; 37(8):721-6. PMID: 22785496.
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    85. Zan J, Cicirelli EM, Mohamed NM, Sibhatu H, Kroll S, Choi O, Choi O, Uhlson CL, Wysoczynski CL, Wysoczinski CL, Murphy RC, Churchill ME, Hill RT, Fuqua C. A complex LuxR-LuxI type quorum sensing network in a roseobacterial marine sponge symbiont activates flagellar motility and inhibits biofilm formation. Mol Microbiol. 2012 Sep; 85(5):916-33. PMID: 22742196; PMCID: PMC3429658.
    86. O'Donnell VB, Murphy RC. New families of bioactive oxidized phospholipids generated by immune cells: identification and signaling actions. Blood. 2012 Sep 06; 120(10):1985-92. PMID: 22802337; PMCID: PMC3437593.
    87. Rudolph MC, Karl Maluf N, Wellberg EA, Johnson CA, Murphy RC, Anderson SM. Mammalian fatty acid synthase activity from crude tissue lysates tracing ¹³C-labeled substrates using gas chromatography-mass spectrometry. Anal Biochem. 2012 Sep 15; 428(2):158-66. PMID: 22728958; PMCID: PMC3415257.
    88. Hutchins PM, Murphy RC. Cholesteryl ester acyl oxidation and remodeling in murine macrophages: formation of oxidized phosphatidylcholine. J Lipid Res. 2012 Aug; 53(8):1588-97. PMID: 22665166; PMCID: PMC3540862.
    89. Eun JC, Moore EE, Mauchley DC, Johnson CA, Meng X, Banerjee A, Wohlauer MV, Zarini S, Gijón MA, Murphy RC. The 5-lipoxygenase pathway is required for acute lung injury following hemorrhagic shock. Shock. 2012 Jun; 37(6):599-604. PMID: 22392149; PMCID: PMC3357208.
    90. Mulligan CM, Sparagna GC, Le CH, De Mooy AB, Routh MA, Holmes MG, Hickson-Bick DL, Zarini S, Murphy RC, Xu FY, Hatch GM, McCune SA, Moore RL, Chicco AJ. Dietary linoleate preserves cardiolipin and attenuates mitochondrial dysfunction in the failing rat heart. Cardiovasc Res. 2012 Jun 01; 94(3):460-8. PMID: 22411972; PMCID: PMC3353802.
    91. Sanford SD, Yun BG, Leslie CC, Murphy RC, Pfenninger KH. Group IVA phospholipase A2 is necessary for growth cone repulsion and collapse. J Neurochem. 2012 Mar; 120(6):974-84. PMID: 22220903; PMCID: PMC3296835.
    92. Yao Y, Harrison KA, Al-Hassani M, Murphy RC, Rezania S, Konger RL, Travers JB. Platelet-activating factor receptor agonists mediate xeroderma pigmentosum A photosensitivity. J Biol Chem. 2012 Mar 16; 287(12):9311-21. PMID: 22303003; PMCID: PMC3308814.
    93. O'Donnell K, Murphy R, Ostermann J, Masnick M, Whetten RA, Madden E, Thielman NM, Whetten K. A brief assessment of learning for orphaned and abandoned children in low and middle income countries. AIDS Behav. 2012 Feb; 16(2):480-90. PMID: 21538088; PMCID: PMC3817622.
    94. Rong S, Cao Q, Liu M, Seo J, Jia L, Boudyguina E, Gebre AK, Colvin PL, Smith TL, Murphy RC, Mishra N, Parks JS. Macrophage 12/15 lipoxygenase expression increases plasma and hepatic lipid levels and exacerbates atherosclerosis. J Lipid Res. 2012 Apr; 53(4):686-95. PMID: 22279185; PMCID: PMC3307645.
    95. Manion M, Rodriguez B, Medvik K, Hardy G, Harding CV, Schooley RT, Pollard R, Asmuth D, Murphy R, Barker E, Brady KE, Landay A, Funderburg N, Sieg SF, Lederman MM. Interferon-alpha administration enhances CD8+ T cell activation in HIV infection. PLoS One. 2012; 7(1):e30306. PMID: 22291932; PMCID: PMC3265460.
    96. Barajas-Espinosa A, Ni NC, Yan D, Zarini S, Murphy RC, Funk CD. The cysteinyl leukotriene 2 receptor mediates retinal edema and pathological neovascularization in a murine model of oxygen-induced retinopathy. FASEB J. 2012 Mar; 26(3):1100-9. PMID: 22131271.
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    97. Farias SE, Heidenreich KA, Wohlauer MV, Murphy RC, Moore EE. Lipid mediators in cerebral spinal fluid of traumatic brain injured patients. J Trauma. 2011 Nov; 71(5):1211-8. PMID: 21427623.
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    98. Berry KA, Hankin JA, Barkley RM, Spraggins JM, Caprioli RM, Murphy RC. MALDI imaging of lipid biochemistry in tissues by mass spectrometry. Chem Rev. 2011 Oct 12; 111(10):6491-512. PMID: 21942646; PMCID: PMC3199966.
    99. Murphy RC, Merrill AH. Lipidomics and imaging mass spectrometry. Biochim Biophys Acta. 2011 Nov; 1811(11):635-6. PMID: 21983393.
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    100. Hutchins PM, Moore EE, Murphy RC. Electrospray MS/MS reveals extensive and nonspecific oxidation of cholesterol esters in human peripheral vascular lesions. J Lipid Res. 2011 Nov; 52(11):2070-83. PMID: 21885431; PMCID: PMC3196238.
    101. Leiker TJ, Barkley RM, Murphy RC. Analysis of Diacylglycerol Molecular Species in Cellular Lipid Extracts by Normal-Phase LC-Electrospray Mass Spectrometry. Int J Mass Spectrom. 2011 Aug 15; 305(2-3):103-109. PMID: 21860599.
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    102. Saini-Chohan HK, Dakshinamurti S, Taylor WA, Shen GX, Murphy R, Sparagna GC, Hatch GM. Persistent pulmonary hypertension results in reduced tetralinoleoyl-cardiolipin and mitochondrial complex II + III during the development of right ventricular hypertrophy in the neonatal pig heart. Am J Physiol Heart Circ Physiol. 2011 Oct; 301(4):H1415-24. PMID: 21841017.
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    103. Robertson K, Kumwenda J, Supparatpinyo K, Jiang JH, Evans S, Campbell TB, Price RW, Murphy R, Hall C, Marra CM, Marcus C, Berzins B, Masih R, Santos B, Silva MT, Kumarasamy N, Walawander A, Nair A, Tripathy S, Kanyama C, Hosseinipour M, Montano S, La Rosa A, Amod F, Sanne I, Firnhaber C, Hakim J, Brouwers P. A multinational study of neurological performance in antiretroviral therapy-naïve HIV-1-infected persons in diverse resource-constrained settings. J Neurovirol. 2011 Oct; 17(5):438-47. PMID: 21786076; PMCID: PMC3362044.
    104. Murphy RC, Leiker TJ, Barkley RM. Glycerolipid and cholesterol ester analyses in biological samples by mass spectrometry. Biochim Biophys Acta. 2011 Nov; 1811(11):776-83. PMID: 21757029; PMCID: PMC3205286.
    105. Murphy RC, Gaskell SJ. New applications of mass spectrometry in lipid analysis. J Biol Chem. 2011 Jul 22; 286(29):25427-33. PMID: 21632539; PMCID: PMC3138261.
    106. Murphy RC, Kawashima A, Peller PJ. The utility of 11C-choline PET/CT for imaging prostate cancer: a pictorial guide. AJR Am J Roentgenol. 2011 Jun; 196(6):1390-8. PMID: 21606304.
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    107. Murphy RC, Hankin JA, Barkley RM, Zemski Berry KA. MALDI imaging of lipids after matrix sublimation/deposition. Biochim Biophys Acta. 2011 Nov; 1811(11):970-5. PMID: 21571091; PMCID: PMC3202086.
    108. Berry KA, Li B, Reynolds SD, Barkley RM, Gijón MA, Hankin JA, Henson PM, Murphy RC. MALDI imaging MS of phospholipids in the mouse lung. J Lipid Res. 2011 Aug; 52(8):1551-60. PMID: 21508254; PMCID: PMC3137021.
    109. Hankin JA, Farias SE, Barkley RM, Heidenreich K, Frey LC, Hamazaki K, Kim HY, Murphy RC. MALDI mass spectrometric imaging of lipids in rat brain injury models. J Am Soc Mass Spectrom. 2011 Jun; 22(6):1014-21. PMID: 21953042; PMCID: PMC4537074.
    110. Hutchins PM, Murphy RC. Peroxide bond driven dissociation of hydroperoxy-cholesterol esters following collision induced dissociation. J Am Soc Mass Spectrom. 2011 May; 22(5):867-74. PMID: 21472521; PMCID: PMC3565457.
    111. Frasch SC, Fernandez-Boyanapalli RF, Berry KZ, Leslie CC, Bonventre JV, Murphy RC, Henson PM, Bratton DL. Signaling via macrophage G2A enhances efferocytosis of dying neutrophils by augmentation of Rac activity. J Biol Chem. 2011 Apr 08; 286(14):12108-22. PMID: 21297111; PMCID: PMC3069415.
    112. Kandasamy P, Zarini S, Chan ED, Leslie CC, Murphy RC, Voelker DR. Pulmonary surfactant phosphatidylglycerol inhibits Mycoplasma pneumoniae-stimulated eicosanoid production from human and mouse macrophages. J Biol Chem. 2011 Mar 11; 286(10):7841-53. PMID: 21205826; PMCID: PMC3048671.
    113. Refuerzo JS, Straub H, Murphy R, Salter L, Ramin SM, Blackwell SC. Computerized physician order entry reduces medication turnaround time of labor induction agents. Am J Perinatol. 2011 Apr; 28(4):253-8. PMID: 21082536.
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    114. Morgan AH, Hammond VJ, Morgan L, Thomas CP, Tallman KA, Garcia-Diaz YR, McGuigan C, Serpi M, Porter NA, Murphy RC, O'Donnell VB. Quantitative assays for esterified oxylipins generated by immune cells. Nat Protoc. 2010 Dec; 5(12):1919-31. PMID: 21127486; PMCID: PMC3678246.
    115. Murphy RC, Axelsen PH. Mass spectrometric analysis of long-chain lipids. Mass Spectrom Rev. 2011 Jul-Aug; 30(4):579-99. PMID: 21656842; PMCID: PMC3117083.
    116. Hankin JA, Murphy RC. Relationship between MALDI IMS intensity and measured quantity of selected phospholipids in rat brain sections. Anal Chem. 2010 Oct 15; 82(20):8476-84. PMID: 20853893; PMCID: PMC3025046.
    117. Dennis EA, Deems RA, Harkewicz R, Quehenberger O, Brown HA, Milne SB, Myers DS, Glass CK, Hardiman G, Reichart D, Merrill AH, Sullards MC, Wang E, Murphy RC, Raetz CR, Garrett TA, Guan Z, Ryan AC, Russell DW, McDonald JG, Thompson BM, Shaw WA, Sud M, Zhao Y, Gupta S, Maurya MR, Fahy E, Subramaniam S. A mouse macrophage lipidome. J Biol Chem. 2010 Dec 17; 285(51):39976-85. PMID: 20923771; PMCID: PMC3000979.
    118. Chen M, Lam BK, Luster AD, Zarini S, Murphy RC, Bair AM, Soberman RJ, Lee DM. Joint tissues amplify inflammation and alter their invasive behavior via leukotriene B4 in experimental inflammatory arthritis. J Immunol. 2010 Nov 01; 185(9):5503-11. PMID: 20876351; PMCID: PMC3690310.
    119. Hong X, Zang J, White J, Wang C, Pan CH, Zhao R, Murphy RC, Dai S, Henson P, Kappler JW, Hagman J, Zhang G. Interaction of JMJD6 with single-stranded RNA. Proc Natl Acad Sci U S A. 2010 Aug 17; 107(33):14568-72. PMID: 20679243; PMCID: PMC2930430.
    120. Quehenberger O, Armando AM, Brown AH, Milne SB, Myers DS, Merrill AH, Bandyopadhyay S, Jones KN, Kelly S, Shaner RL, Sullards CM, Wang E, Murphy RC, Barkley RM, Leiker TJ, Raetz CR, Guan Z, Laird GM, Six DA, Russell DW, McDonald JG, Subramaniam S, Fahy E, Dennis EA. Lipidomics reveals a remarkable diversity of lipids in human plasma. J Lipid Res. 2010 Nov; 51(11):3299-305. PMID: 20671299; PMCID: PMC2952570.
    121. Suram S, Gangelhoff TA, Taylor PR, Rosas M, Brown GD, Bonventre JV, Akira S, Uematsu S, Williams DL, Murphy RC, Leslie CC. Pathways regulating cytosolic phospholipase A2 activation and eicosanoid production in macrophages by Candida albicans. J Biol Chem. 2010 Oct 01; 285(40):30676-85. PMID: 20643646; PMCID: PMC2945562.
    122. Montrose DC, Kadaveru K, Ilsley JN, Root SH, Rajan TV, Ramesh M, Nichols FC, Liang BT, Sonin D, Hand AR, Zarini S, Murphy RC, Belinsky GS, Nakanishi M, Rosenberg DW. cPLA2 is protective against COX inhibitor-induced intestinal damage. Toxicol Sci. 2010 Sep; 117(1):122-32. PMID: 20562220; PMCID: PMC2923287.
    123. Deeley JM, Hankin JA, Friedrich MG, Murphy RC, Truscott RJ, Mitchell TW, Blanksby SJ. Sphingolipid distribution changes with age in the human lens. J Lipid Res. 2010 Sep; 51(9):2753-60. PMID: 20547889; PMCID: PMC2918457.
    124. Sala A, Folco G, Murphy RC. Transcellular biosynthesis of eicosanoids. Pharmacol Rep. 2010 May-Jun; 62(3):503-10. PMID: 20631414; PMCID: PMC4535419.
    125. Patwardhan AM, Akopian AN, Ruparel NB, Diogenes A, Weintraub ST, Uhlson C, Murphy RC, Hargreaves KM. Heat generates oxidized linoleic acid metabolites that activate TRPV1 and produce pain in rodents. J Clin Invest. 2010 May; 120(5):1617-26. PMID: 20424317; PMCID: PMC2860941.
    126. Kosmider B, Loader JE, Murphy RC, Mason RJ. Apoptosis induced by ozone and oxysterols in human alveolar epithelial cells. Free Radic Biol Med. 2010 Jun 01; 48(11):1513-24. PMID: 20219673; PMCID: PMC2965594.
    127. Murphy RC, Fahy E. Isoprostane nomenclature: more suggestions. Prostaglandins Leukot Essent Fatty Acids. 2010 Feb-Mar; 82(2-3):69-70. PMID: 20092991; PMCID: PMC2823939.
    128. Thomas CP, Morgan LT, Maskrey BH, Murphy RC, Kühn H, Hazen SL, Goodall AH, Hamali HA, Collins PW, O'Donnell VB. Phospholipid-esterified eicosanoids are generated in agonist-activated human platelets and enhance tissue factor-dependent thrombin generation. J Biol Chem. 2010 Mar 05; 285(10):6891-903. PMID: 20061396; PMCID: PMC2844139.
    129. Zemski Berry KA, Turner WW, VanNieuwenhze MS, Murphy RC. Characterization of oxidized phosphatidylethanolamine derived from RAW 264.7 cells using 4-(dimethylamino)benzoic acid derivatives. Eur J Mass Spectrom (Chichester). 2010; 16(3):463-70. PMID: 20530831; PMCID: PMC3086548.
    130. Wynalda KM, Murphy RC. Low-concentration ozone reacts with plasmalogen glycerophosphoethanolamine lipids in lung surfactant. Chem Res Toxicol. 2010 Jan; 23(1):108-17. PMID: 19916514; PMCID: PMC2807911.
    131. Basselin M, Kim HW, Chen M, Ma K, Rapoport SI, Murphy RC, Farias SE. Lithium modifies brain arachidonic and docosahexaenoic metabolism in rat lipopolysaccharide model of neuroinflammation. J Lipid Res. 2010 May; 51(5):1049-56. PMID: 20040630; PMCID: PMC2853431.
    132. Steinhauer J, Gijón MA, Riekhof WR, Voelker DR, Murphy RC, Treisman JE. Drosophila lysophospholipid acyltransferases are specifically required for germ cell development. Mol Biol Cell. 2009 Dec; 20(24):5224-35. PMID: 19864461; PMCID: PMC2793297.
    133. Farias S, Frey LC, Murphy RC, Heidenreich KA. Injury-related production of cysteinyl leukotrienes contributes to brain damage following experimental traumatic brain injury. J Neurotrauma. 2009 Nov; 26(11):1977-86. PMID: 19886806; PMCID: PMC2822801.
    134. Talahalli R, Zarini S, Sheibani N, Murphy RC, Gubitosi-Klug RA. Increased synthesis of leukotrienes in the mouse model of diabetic retinopathy. Invest Ophthalmol Vis Sci. 2010 Mar; 51(3):1699-708. PMID: 19834040; PMCID: PMC2868429.
    135. Axelsen PH, Murphy RC. Quantitative analysis of phospholipids containing arachidonate and docosahexaenoate chains in microdissected regions of mouse brain. J Lipid Res. 2010 Mar; 51(3):660-71. PMID: 19767534; PMCID: PMC2817596.
    136. Zachman DK, Chicco AJ, McCune SA, Murphy RC, Moore RL, Sparagna GC. The role of calcium-independent phospholipase A2 in cardiolipin remodeling in the spontaneously hypertensive heart failure rat heart. J Lipid Res. 2010 Mar; 51(3):525-34. PMID: 19741254; PMCID: PMC2817582.
    137. Brown HA, Murphy RC. Working towards an exegesis for lipids in biology. Nat Chem Biol. 2009 Sep; 5(9):602-6. PMID: 19690530; PMCID: PMC3785062.
    138. O'Shea KM, Khairallah RJ, Sparagna GC, Xu W, Hecker PA, Robillard-Frayne I, Des Rosiers C, Kristian T, Murphy RC, Fiskum G, Stanley WC. Dietary omega-3 fatty acids alter cardiac mitochondrial phospholipid composition and delay Ca2+-induced permeability transition. J Mol Cell Cardiol. 2009 Dec; 47(6):819-27. PMID: 19703463; PMCID: PMC2783943.
    139. Zemski Berry KA, Turner WW, VanNieuwenhze MS, Murphy RC. Stable isotope labeled 4-(dimethylamino)benzoic acid derivatives of glycerophosphoethanolamine lipids. Anal Chem. 2009 Aug 15; 81(16):6633-40. PMID: 20337376; PMCID: PMC2929906.
    140. Shah KB, Duda MK, O'Shea KM, Sparagna GC, Chess DJ, Khairallah RJ, Robillard-Frayne I, Xu W, Murphy RC, Des Rosiers C, Stanley WC. The cardioprotective effects of fish oil during pressure overload are blocked by high fat intake: role of cardiac phospholipid remodeling. Hypertension. 2009 Sep; 54(3):605-11. PMID: 19597033; PMCID: PMC3103889.
    141. Poeckel D, Zemski Berry KA, Murphy RC, Funk CD. Dual 12/15- and 5-lipoxygenase deficiency in macrophages alters arachidonic acid metabolism and attenuates peritonitis and atherosclerosis in ApoE knock-out mice. J Biol Chem. 2009 Jul 31; 284(31):21077-89. PMID: 19509298; PMCID: PMC2742872.
    142. Parti RP, Loper R, Brown GD, Gordon S, Taylor PR, Bonventre JV, Murphy RC, Williams DL, Leslie CC. Cytosolic phospholipase a2 activation by Candida albicans in alveolar macrophages: role of dectin-1. Am J Respir Cell Mol Biol. 2010 Apr; 42(4):415-23. PMID: 19502385; PMCID: PMC2848735.
    143. Zarini S, Gijón MA, Ransome AE, Murphy RC, Sala A. Transcellular biosynthesis of cysteinyl leukotrienes in vivo during mouse peritoneal inflammation. Proc Natl Acad Sci U S A. 2009 May 19; 106(20):8296-301. PMID: 19416808; PMCID: PMC2688893.
    144. Rector CL, Murphy RC. Determination of leukotriene A(4) stabilization by S100A8/A9 proteins using mass spectrometry. J Lipid Res. 2009 Oct; 50(10):2064-71. PMID: 19269927; PMCID: PMC2739761.
    145. Fahy E, Subramaniam S, Murphy RC, Nishijima M, Raetz CR, Shimizu T, Spener F, van Meer G, Wakelam MJ, Dennis EA. Update of the LIPID MAPS comprehensive classification system for lipids. J Lipid Res. 2009 Apr; 50 Suppl:S9-14. PMID: 19098281; PMCID: PMC2674711.
    146. Murphy RC, Hankin JA, Barkley RM. Imaging of lipid species by MALDI mass spectrometry. J Lipid Res. 2009 Apr; 50 Suppl:S317-22. PMID: 19050313; PMCID: PMC2674737.
    147. Berry KA, Henson PM, Murphy RC. Effects of acrolein on leukotriene biosynthesis in human neutrophils. Chem Res Toxicol. 2008 Dec; 21(12):2424-32. PMID: 19548361; PMCID: PMC2772067.
    148. Murphy R, Doerger KM, Nathan MA, Lowe VJ. Pretreatment with diphenoxylate hydrochloride/atropine sulfate (Lomotil) does not decrease physiologic bowel FDG activity on PET/CT scans of the abdomen and pelvis. Mol Imaging Biol. 2009 Mar-Apr; 11(2):114-7. PMID: 19037613.
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    149. Frasch SC, Berry KZ, Fernandez-Boyanapalli R, Jin HS, Leslie C, Henson PM, Murphy RC, Bratton DL. NADPH oxidase-dependent generation of lysophosphatidylserine enhances clearance of activated and dying neutrophils via G2A. J Biol Chem. 2008 Nov 28; 283(48):33736-49. PMID: 18824544; PMCID: PMC2586279.
    150. Bouvier J, Zemski Berry KA, Hullin-Matsuda F, Makino A, Michaud S, Geloën A, Murphy RC, Kobayashi T, Lagarde M, Delton-Vandenbroucke I. Selective decrease of bis(monoacylglycero)phosphate content in macrophages by high supplementation with docosahexaenoic acid. J Lipid Res. 2009 Feb; 50(2):243-55. PMID: 18809971.
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    151. Gijón MA, Riekhof WR, Zarini S, Murphy RC, Voelker DR. Lysophospholipid acyltransferases and arachidonate recycling in human neutrophils. J Biol Chem. 2008 Oct 31; 283(44):30235-45. PMID: 18772128; PMCID: PMC2573059.
    152. Ojesina AI, Chaplin B, Sankalé JL, Murphy R, Idigbe E, Adewole I, Ekong E, Idoko J, Kanki PJ. Interplay of reverse transcriptase inhibitor therapy and gag p6 diversity in HIV type 1 subtype G and CRF02_AG. AIDS Res Hum Retroviruses. 2008 Sep; 24(9):1167-74. PMID: 18729771; PMCID: PMC2928033.
    153. Murphy R, Jahnke K, Houry D. Characteristics of patients who present to the emergency department with molar pregnancy. South Med J. 2008 Aug; 101(8):797-9. PMID: 18622352.
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    154. Chicco AJ, Sparagna GC, McCune SA, Johnson CA, Murphy RC, Bolden DA, Rees ML, Gardner RT, Moore RL. Linoleate-rich high-fat diet decreases mortality in hypertensive heart failure rats compared with lard and low-fat diets. Hypertension. 2008 Sep; 52(3):549-55. PMID: 18663155; PMCID: PMC2864132.
    155. Farias SE, Basselin M, Chang L, Heidenreich KA, Rapoport SI, Murphy RC. Formation of eicosanoids, E2/D2 isoprostanes, and docosanoids following decapitation-induced ischemia, measured in high-energy-microwaved rat brain. J Lipid Res. 2008 Sep; 49(9):1990-2000. PMID: 18503030; PMCID: PMC2515526.
    156. Smith WL, Murphy RC. Oxidized lipids formed non-enzymatically by reactive oxygen species. J Biol Chem. 2008 Jun 06; 283(23):15513-4. PMID: 18285325; PMCID: PMC3259636.
    157. Murphy RC, Johnson KM. Cholesterol, reactive oxygen species, and the formation of biologically active mediators. J Biol Chem. 2008 Jun 06; 283(23):15521-5. PMID: 18285330; PMCID: PMC2414298.
    158. Chicco AJ, McCune SA, Emter CA, Sparagna GC, Rees ML, Bolden DA, Marshall KD, Murphy RC, Moore RL. Low-intensity exercise training delays heart failure and improves survival in female hypertensive heart failure rats. Hypertension. 2008 Apr; 51(4):1096-102. PMID: 18259016.
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    159. Hutchins PM, Barkley RM, Murphy RC. Separation of cellular nonpolar neutral lipids by normal-phase chromatography and analysis by electrospray ionization mass spectrometry. J Lipid Res. 2008 Apr; 49(4):804-13. PMID: 18223242; PMCID: PMC2367097.
    160. Riekhof WR, Wu J, Gijón MA, Zarini S, Murphy RC, Voelker DR. Lysophosphatidylcholine metabolism in Saccharomyces cerevisiae: the role of P-type ATPases in transport and a broad specificity acyltransferase in acylation. J Biol Chem. 2007 Dec 21; 282(51):36853-61. PMID: 17951629.
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    161. Farias SE, Zarini S, Precht T, Murphy RC, Heidenreich KA. Transcellular biosynthesis of cysteinyl leukotrienes in rat neuronal and glial cells. J Neurochem. 2007 Nov; 103(4):1310-8. PMID: 17711426.
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    162. Murphy RC, Gijón MA. Biosynthesis and metabolism of leukotrienes. Biochem J. 2007 Aug 01; 405(3):379-95. PMID: 17623009.
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    163. Zemski Berry KA, Murphy RC. Characterization of acrolein-glycerophosphoethanolamine lipid adducts using electrospray mass spectrometry. Chem Res Toxicol. 2007 Sep; 20(9):1342-51. PMID: 17636891; PMCID: PMC2441484.
    164. Hankin JA, Barkley RM, Murphy RC. Sublimation as a method of matrix application for mass spectrometric imaging. J Am Soc Mass Spectrom. 2007 Sep; 18(9):1646-52. PMID: 17659880; PMCID: PMC2042488.
    165. Thomas MC, Mitchell TW, Harman DG, Deeley JM, Murphy RC, Blanksby SJ. Elucidation of double bond position in unsaturated lipids by ozone electrospray ionization mass spectrometry. Anal Chem. 2007 Jul 01; 79(13):5013-22. PMID: 17547368; PMCID: PMC3083263.
    166. Frasch SC, Zemski-Berry K, Murphy RC, Borregaard N, Henson PM, Bratton DL. Lysophospholipids of different classes mobilize neutrophil secretory vesicles and induce redundant signaling through G2A. J Immunol. 2007 May 15; 178(10):6540-8. PMID: 17475884.
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    167. Sparagna GC, Chicco AJ, Murphy RC, Bristow MR, Johnson CA, Rees ML, Maxey ML, McCune SA, Moore RL. Loss of cardiac tetralinoleoyl cardiolipin in human and experimental heart failure. J Lipid Res. 2007 Jul; 48(7):1559-70. PMID: 17426348.
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    168. Surviladze Z, Harrison KA, Murphy RC, Wilson BS. FcepsilonRI and Thy-1 domains have unique protein and lipid compositions. J Lipid Res. 2007 Jun; 48(6):1325-35. PMID: 17387221.
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    169. Murphy RC, James PF, McAnoy AM, Krank J, Duchoslav E, Barkley RM. Detection of the abundance of diacylglycerol and triacylglycerol molecular species in cells using neutral loss mass spectrometry. Anal Biochem. 2007 Jul 01; 366(1):59-70. PMID: 17442253; PMCID: PMC2034497.
    170. Fitzgerald M, Murphy RC. Electrospray mass spectrometry of human hair wax esters. J Lipid Res. 2007 May; 48(5):1231-46. PMID: 17277382.
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    171. Krank J, Murphy RC, Barkley RM, Duchoslav E, McAnoy A. Qualitative analysis and quantitative assessment of changes in neutral glycerol lipid molecular species within cells. Methods Enzymol. 2007; 432:1-20. PMID: 17954211.
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    172. Gijón MA, Zarini S, Murphy RC. Biosynthesis of eicosanoids and transcellular metabolism of leukotrienes in murine bone marrow cells. J Lipid Res. 2007 Mar; 48(3):716-25. PMID: 17179116.
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    173. Sud M, Fahy E, Cotter D, Brown A, Dennis EA, Glass CK, Merrill AH, Murphy RC, Raetz CR, Russell DW, Subramaniam S. LMSD: LIPID MAPS structure database. Nucleic Acids Res. 2007 Jan; 35(Database issue):D527-32. PMID: 17098933; PMCID: PMC1669719.
    174. Folco G, Murphy RC. Eicosanoid transcellular biosynthesis: from cell-cell interactions to in vivo tissue responses. Pharmacol Rev. 2006 Sep; 58(3):375-88. PMID: 16968946.
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    175. Zarini S, Gijón MA, Folco G, Murphy RC. Effect of arachidonic acid reacylation on leukotriene biosynthesis in human neutrophils stimulated with granulocyte-macrophage colony-stimulating factor and formyl-methionyl-leucyl-phenylalanine. J Biol Chem. 2006 Apr 14; 281(15):10134-42. PMID: 16495221.
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    176. Raetz CR, Garrett TA, Reynolds CM, Shaw WA, Moore JD, Smith DC, Ribeiro AA, Murphy RC, Ulevitch RJ, Fearns C, Reichart D, Glass CK, Benner C, Subramaniam S, Harkewicz R, Bowers-Gentry RC, Buczynski MW, Cooper JA, Deems RA, Dennis EA. Kdo2-Lipid A of Escherichia coli, a defined endotoxin that activates macrophages via TLR-4. J Lipid Res. 2006 May; 47(5):1097-111. PMID: 16479018.
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    177. Kirwan JP, Gould TA, Schweizer HP, Bearden SW, Murphy RC, Churchill ME. Quorum-sensing signal synthesis by the Yersinia pestis acyl-homoserine lactone synthase YspI. J Bacteriol. 2006 Jan; 188(2):784-8. PMID: 16385067; PMCID: PMC1347278.
    178. Chiba H, Piboonpocanun S, Mitsuzawa H, Kuronuma K, Murphy RC, Voelker DR. Pulmonary surfactant proteins and lipids as modulators of inflammation and innate immunity. Respirology. 2006 Jan; 11 Suppl:S2-6. PMID: 16423264.
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    179. Gould TA, Herman J, Krank J, Murphy RC, Churchill ME. Specificity of acyl-homoserine lactone synthases examined by mass spectrometry. J Bacteriol. 2006 Jan; 188(2):773-83. PMID: 16385066; PMCID: PMC1347284.
    180. Christmas P, Tolentino K, Primo V, Berry KZ, Murphy RC, Chen M, Lee DM, Soberman RJ. Cytochrome P-450 4F18 is the leukotriene B4 omega-1/omega-2 hydroxylase in mouse polymorphonuclear leukocytes: identification as the functional orthologue of human polymorphonuclear leukocyte CYP4F3A in the down-regulation of responses to LTB4. J Biol Chem. 2006 Mar 17; 281(11):7189-96. PMID: 16380383.
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    181. Zemski Berry KA, Murphy RC. Analysis of polyunsaturated aminophospholipid molecular species using isotope-tagged derivatives and tandem mass spectrometry/mass spectrometry/mass spectrometry. Anal Biochem. 2006 Feb 01; 349(1):118-28. PMID: 16384548.
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    182. Murphy RC, Barkley RM, Zemski Berry K, Hankin J, Harrison K, Johnson C, Krank J, McAnoy A, Uhlson C, Zarini S. Electrospray ionization and tandem mass spectrometry of eicosanoids. Anal Biochem. 2005 Nov 01; 346(1):1-42. PMID: 15961057.
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    183. McAnoy AM, Wu CC, Murphy RC. Direct qualitative analysis of triacylglycerols by electrospray mass spectrometry using a linear ion trap. J Am Soc Mass Spectrom. 2005 Sep; 16(9):1498-509. PMID: 16019221.
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    184. Murphy RC, Raetz CR, Reynolds CM, Barkley RM. Mass spectrometry advances in lipidomica: collision-induced decomposition of Kdo2-lipid A. Prostaglandins Other Lipid Mediat. 2005 Sep; 77(1-4):131-40. PMID: 16099398; PMCID: PMC4535423.
    185. Marathe GK, Johnson C, Billings SD, Southall MD, Pei Y, Spandau D, Murphy RC, Zimmerman GA, McIntyre TM, Travers JB. Ultraviolet B radiation generates platelet-activating factor-like phospholipids underlying cutaneous damage. J Biol Chem. 2005 Oct 21; 280(42):35448-57. PMID: 16115894.
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    186. Nomura T, Chang HY, Lu R, Hankin J, Murphy RC, Schuster VL. Prostaglandin signaling in the renal collecting duct: release, reuptake, and oxidation in the same cell. J Biol Chem. 2005 Aug 05; 280(31):28424-9. PMID: 15855165.
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    187. Sparagna GC, Johnson CA, McCune SA, Moore RL, Murphy RC. Quantitation of cardiolipin molecular species in spontaneously hypertensive heart failure rats using electrospray ionization mass spectrometry. J Lipid Res. 2005 Jun; 46(6):1196-204. PMID: 15772420.
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    188. Berry KA, Murphy RC. Analysis of cell membrane aminophospholipids as isotope-tagged derivatives. J Lipid Res. 2005 May; 46(5):1038-46. PMID: 15716579.
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    189. Fahy E, Subramaniam S, Brown HA, Glass CK, Merrill AH, Murphy RC, Raetz CR, Russell DW, Seyama Y, Shaw W, Shimizu T, Spener F, van Meer G, VanNieuwenhze MS, White SH, Witztum JL, Dennis EA. A comprehensive classification system for lipids. J Lipid Res. 2005 May; 46(5):839-61. PMID: 15722563.
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    190. Zemski Berry KA, Murphy RC. Free radical oxidation of plasmalogen glycerophosphocholine containing esterified docosahexaenoic acid: structure determination by mass spectrometry. Antioxid Redox Signal. 2005 Jan-Feb; 7(1-2):157-69. PMID: 15650405.
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    191. Quittnat F, Nishikawa Y, Stedman TT, Voelker DR, Choi JY, Zahn MM, Murphy RC, Barkley RM, Pypaert M, Joiner KA, Coppens I. On the biogenesis of lipid bodies in ancient eukaryotes: synthesis of triacylglycerols by a Toxoplasma DGAT1-related enzyme. Mol Biochem Parasitol. 2004 Nov; 138(1):107-22. PMID: 15500922.
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    192. Zhang Q, Southall MD, Mezsick SM, Johnson C, Murphy RC, Konger RL, Travers JB. Epidermal peroxisome proliferator-activated receptor gamma as a target for ultraviolet B radiation. J Biol Chem. 2005 Jan 07; 280(1):73-9. PMID: 15516334.
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    193. Piboonpocanun S, Chiba H, Mitsuzawa H, Martin W, Murphy RC, Harbeck RJ, Voelker DR. Surfactant protein A binds Mycoplasma pneumoniae with high affinity and attenuates its growth by recognition of disaturated phosphatidylglycerols. J Biol Chem. 2005 Jan 07; 280(1):9-17. PMID: 15498759.
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    194. Blaine SA, Meyer AM, Hurteau G, Wick M, Hankin JA, Murphy RC, Dannenberg AJ, Geraci MW, Subbaramaiah K, Nemenoff RA. Targeted over-expression of mPGES-1 and elevated PGE2 production is not sufficient for lung tumorigenesis in mice. Carcinogenesis. 2005 Jan; 26(1):209-17. PMID: 15471895.
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    195. Hankin JA, Murphy RC. Mass spectrometric quantitation of deoxyguanosine and leukotriene A4-deoxyguanosine adducts of DNA. Anal Biochem. 2004 Oct 01; 333(1):156-64. PMID: 15351292.
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    196. Zemski Berry KA, Murphy RC. Electrospray ionization tandem mass spectrometry of glycerophosphoethanolamine plasmalogen phospholipids. J Am Soc Mass Spectrom. 2004 Oct; 15(10):1499-508. PMID: 15465363.
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    197. Zimmer JS, Dyckes DF, Bernlohr DA, Murphy RC. Fatty acid binding proteins stabilize leukotriene A4: competition with arachidonic acid but not other lipoxygenase products. J Lipid Res. 2004 Nov; 45(11):2138-44. PMID: 15342681.
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    198. Nick JA, Coldren CD, Geraci MW, Poch KR, Fouty BW, O'Brien J, Gruber M, Zarini S, Murphy RC, Kuhn K, Richter D, Kast KR, Abraham E. Recombinant human activated protein C reduces human endotoxin-induced pulmonary inflammation via inhibition of neutrophil chemotaxis. Blood. 2004 Dec 15; 104(13):3878-85. PMID: 15339848.
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    199. Pulfer MK, Taube C, Gelfand E, Murphy RC. Ozone exposure in vivo and formation of biologically active oxysterols in the lung. J Pharmacol Exp Ther. 2005 Jan; 312(1):256-64. PMID: 15316091.
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    200. Choi JY, Martin WE, Murphy RC, Voelker DR. Phosphatidylcholine and N-methylated phospholipids are nonessential in Saccharomyces cerevisiae. J Biol Chem. 2004 Oct 01; 279(40):42321-30. PMID: 15269223.
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    201. Fessler MB, Arndt PG, Frasch SC, Lieber JG, Johnson CA, Murphy RC, Nick JA, Bratton DL, Malcolm KC, Worthen GS. Lipid rafts regulate lipopolysaccharide-induced activation of Cdc42 and inflammatory functions of the human neutrophil. J Biol Chem. 2004 Sep 17; 279(38):39989-98. PMID: 15262974.
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    202. Pulfer MK, Murphy RC. Formation of biologically active oxysterols during ozonolysis of cholesterol present in lung surfactant. J Biol Chem. 2004 Jun 18; 279(25):26331-8. PMID: 15096493.
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    203. Di Gennaro A, Carnini C, Buccellati C, Ballerio R, Zarini S, Fumagalli F, Viappiani S, Librizzi L, Hernandez A, Murphy RC, Constantin G, De Curtis M, Folco G, Sala A. Cysteinyl-leukotrienes receptor activation in brain inflammatory reactions and cerebral edema formation: a role for transcellular biosynthesis of cysteinyl-leukotrienes. FASEB J. 2004 May; 18(7):842-4. PMID: 15001558.
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    204. Murphy RC, Messer A. A single-chain Fv intrabody provides functional protection against the effects of mutant protein in an organotypic slice culture model of Huntington's disease. Brain Res Mol Brain Res. 2004 Feb 05; 121(1-2):141-5. PMID: 14969746.
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    205. Pulfer MK, Harrison K, Murphy RC. Direct electrospray tandem mass spectrometry of the unstable hydroperoxy bishemiacetal product derived from cholesterol ozonolysis. J Am Soc Mass Spectrom. 2004 Feb; 15(2):194-202. PMID: 14766287.
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    206. Bowers R, Cool C, Murphy RC, Tuder RM, Hopken MW, Flores SC, Voelkel NF. Oxidative stress in severe pulmonary hypertension. Am J Respir Crit Care Med. 2004 Mar 15; 169(6):764-9. PMID: 14701708.
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    207. Dickinson Zimmer JS, Voelker DR, Bernlohr DA, Murphy RC. Stabilization of leukotriene A4 by epithelial fatty acid-binding protein in the rat basophilic leukemia cell. J Biol Chem. 2004 Feb 27; 279(9):7420-6. PMID: 14676186.
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    208. Pulfer M, Murphy RC. Electrospray mass spectrometry of phospholipids. Mass Spectrom Rev. 2003 Sep-Oct; 22(5):332-64. PMID: 12949918.
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    209. Ghosh M, Stewart A, Tucker DE, Bonventre JV, Murphy RC, Leslie CC. Role of cytosolic phospholipase A(2) in prostaglandin E(2) production by lung fibroblasts. Am J Respir Cell Mol Biol. 2004 Jan; 30(1):91-100. PMID: 12842849.
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    210. Watanabe J, Marathe GK, Neilsen PO, Weyrich AS, Harrison KA, Murphy RC, Zimmerman GA, McIntyre TM. Endotoxins stimulate neutrophil adhesion followed by synthesis and release of platelet-activating factor in microparticles. J Biol Chem. 2003 Aug 29; 278(35):33161-8. PMID: 12810708.
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    211. Liu Y, Hong X, Kappler J, Jiang L, Zhang R, Xu L, Pan CH, Martin WE, Murphy RC, Shu HB, Dai S, Zhang G. Ligand-receptor binding revealed by the TNF family member TALL-1. Nature. 2003 May 01; 423(6935):49-56. PMID: 12721620.
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    212. Berry KA, Borgeat P, Gosselin J, Flamand L, Murphy RC. Urinary metabolites of leukotriene B4 in the human subject. J Biol Chem. 2003 Jul 04; 278(27):24449-60. PMID: 12709426.
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    213. Hankin JA, Jones DN, Murphy RC. Covalent binding of leukotriene A4 to DNA and RNA. Chem Res Toxicol. 2003 Apr; 16(4):551-61. PMID: 12703973.
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    214. Zarini S, Murphy RC. Biosynthesis of 5-oxo-6,8,11,14-eicosatetraenoic acid from 5-hydroperoxyeicosatetraenoic acid in the murine macrophage. J Biol Chem. 2003 Mar 28; 278(13):11190-6. PMID: 12547823.
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    215. Hankin JA, Murphy RC. Covalent binding of leukotriene A4 to nucleosides, nucleotides, and nucleic acids. Adv Exp Med Biol. 2003; 525:29-33. PMID: 12751732.
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    216. Sala A, Profita M, Siena L, Henson PM, Murphy RC, Paternò A, Bonanno A, Riccobono L, Mirabella A, Bonsignore G, Vignola AM. Il-4-induced lipid mediators class switching in human normal mononuclear phagocytes. Adv Exp Med Biol. 2003; 525:15-8. PMID: 12751729.
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    217. Stonehouse MJ, Cota-Gomez A, Parker SK, Martin WE, Hankin JA, Murphy RC, Chen W, Lim KB, Hackett M, Vasil AI, Vasil ML. A novel class of microbial phosphocholine-specific phospholipases C. Mol Microbiol. 2002 Nov; 46(3):661-76. PMID: 12410824.
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    218. Dickinson JS, Murphy RC. Mass spectrometric analysis of leukotriene A4 and other chemically reactive metabolites of arachidonic acid. J Am Soc Mass Spectrom. 2002 Oct; 13(10):1227-34. PMID: 12387329.
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    219. Wilderman PJ, Vasil AI, Martin WE, Murphy RC, Vasil ML. Pseudomonas aeruginosa synthesizes phosphatidylcholine by use of the phosphatidylcholine synthase pathway. J Bacteriol. 2002 Sep; 184(17):4792-9. PMID: 12169604; PMCID: PMC135270.
    220. Murphy RC, Zarini S. Glutathione adducts of oxyeicosanoids. Prostaglandins Other Lipid Mediat. 2002 Aug; 68-69:471-82. PMID: 12432937.
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    221. Uhlson C, Harrison K, Allen CB, Ahmad S, White CW, Murphy RC. Oxidized phospholipids derived from ozone-treated lung surfactant extract reduce macrophage and epithelial cell viability. Chem Res Toxicol. 2002 Jul; 15(7):896-906. PMID: 12118999.
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    222. Profita M, Sala A, Siena L, Henson PM, Murphy RC, Paternò A, Bonanno A, Riccobono L, Mirabella A, Bonsignore G, Vignola AM. Leukotriene B4 production in human mononuclear phagocytes is modulated by interleukin-4-induced 15-lipoxygenase. J Pharmacol Exp Ther. 2002 Mar; 300(3):868-75. PMID: 11861792.
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    223. Petersen JE, Hiran TS, Goebel WS, Johnson C, Murphy RC, Azmi FH, Hood AF, Travers JB, Dinauer MC. Enhanced cutaneous inflammatory reactions to Aspergillus fumigatus in a murine model of chronic granulomatous disease. J Invest Dermatol. 2002 Mar; 118(3):424-9. PMID: 11874480.
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    224. Falloon J, Ait-Khaled M, Thomas DA, Brosgart CL, Eron Jr JJ, Feinberg J, Flanigan TP, Hammer SM, Kraus PW, Murphy R, Torres R, Masur H. HIV-1 genotype and phenotype correlate with virological response to abacavir, amprenavir and efavirenz in treatment-experienced patients. AIDS. 2002 Feb 15; 16(3):387-96. PMID: 11834950.
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    225. Hevko JM, Murphy RC. Formation of murine macrophage-derived 5-oxo-7-glutathionyl-8,11,14-eicosatrienoic acid (FOG7) is catalyzed by leukotriene C4 synthase. J Biol Chem. 2002 Mar 01; 277(9):7037-43. PMID: 11748223.
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    226. Bauer AK, Dwyer-Nield LD, Hankin JA, Murphy RC, Malkinson AM. The lung tumor promoter, butylated hydroxytoluene (BHT), causes chronic inflammation in promotion-sensitive BALB/cByJ mice but not in promotion-resistant CXB4 mice. Toxicology. 2001 Dec 01; 169(1):1-15. PMID: 11696405.
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    227. Liu Y, Manna A, Li R, Martin WE, Murphy RC, Cheung AL, Zhang G. Crystal structure of the SarR protein from Staphylococcus aureus. Proc Natl Acad Sci U S A. 2001 Jun 05; 98(12):6877-82. PMID: 11381122; PMCID: PMC34446.
    228. Travers JB, Huff JC, Rola-Pleszczynski M, Gelfand EW, Morelli JG, Murphy RC. Identification of functional platelet-activating factor receptors on human keratinocytes. J Invest Dermatol. 1995 Dec; 105(6):816-23. PMID: 7490477.
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    229. Voelkel NF, Czartolomna J, Simpson J, Murphy RC. FMLP causes eicosanoid-dependent vasoconstriction and edema in lungs from endotoxin-primed rats. Am Rev Respir Dis. 1992 Mar; 145(3):701-11. PMID: 1546853.
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    230. Bernstrom K, Kayganich K, Murphy RC, Fitzpatrick FA. Incorporation and distribution of epoxyeicosatrienoic acids into cellular phospholipids. J Biol Chem. 1992 Feb 25; 267(6):3686-90. PMID: 1740420.
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    231. Morelli JG, Hake SS, Murphy RC, Norris DA. Leukotriene B4-induced human melanocyte pigmentation and leukotriene C4-induced human melanocyte growth are inhibited by different isoquinolinesulfonamides. J Invest Dermatol. 1992 Jan; 98(1):55-8. PMID: 1309461.
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    232. Morelli JG, Norris DA, Lyons MB, Murphy RC. Metabolism of exogenous leukotrienes by cultured human keratinocytes. J Invest Dermatol. 1990 May; 94(5):681-4. PMID: 2157767.
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    233. Miadonna A, Tedeschi A, Brasca C, Folco G, Sala A, Murphy RC. Mediator release after endobronchial antigen challenge in patients with respiratory allergy. J Allergy Clin Immunol. 1990 May; 85(5):906-13. PMID: 1692050.
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    234. Fradin A, Zirrolli JA, Maclouf J, Vausbinder L, Henson PM, Murphy RC. Platelet-activating factor and leukotriene biosynthesis in whole blood. A model for the study of transcellular arachidonate metabolism. J Immunol. 1989 Dec 01; 143(11):3680-5. PMID: 2555415.
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    235. Morelli JG, Yohn JJ, Lyons MB, Murphy RC, Norris DA. Leukotrienes C4 and D4 as potent mitogens for cultured human neonatal melanocytes. J Invest Dermatol. 1989 Dec; 93(6):719-22. PMID: 2584737.
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    236. Maclouf J, Murphy RC, Henson PM. Transcellular sulfidopeptide leukotriene biosynthetic capacity of vascular cells. Blood. 1989 Aug 01; 74(2):703-7. PMID: 2546629.
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    237. Chang SW, Westcott JY, Pickett WC, Murphy RC, Voelkel NF. Endotoxin-induced lung injury in rats: role of eicosanoids. J Appl Physiol (1985). 1989 May; 66(5):2407-18. PMID: 2501283.
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    238. Fitzpatrick FA, Murphy RC. Cytochrome P-450 metabolism of arachidonic acid: formation and biological actions of "epoxygenase"-derived eicosanoids. Pharmacol Rev. 1988 Dec; 40(4):229-41. PMID: 3072574.
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    239. Murphy RC, Falck JR, Lumin S, Yadagiri P, Zirrolli JA, Balazy M, Masferrer JL, Abraham NG, Schwartzman ML. 12(R)-hydroxyeicosatrienoic acid: a vasodilator cytochrome P-450-dependent arachidonate metabolite from the bovine corneal epithelium. J Biol Chem. 1988 Nov 15; 263(32):17197-202. PMID: 3141417.
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    240. Santoro TJ, Morris DH, Murphy RC, Baker RC. Aberrant production of leukotriene C4 by macrophages from autoimmune-prone mice. J Exp Med. 1988 Aug 01; 168(2):783-8. PMID: 3137306; PMCID: PMC2188998.
    241. Stene DO, Murphy RC. Metabolism of leukotriene E4 in isolated rat hepatocytes. Identification of beta-oxidation products of sulfidopeptide leukotrienes. J Biol Chem. 1988 Feb 25; 263(6):2773-8. PMID: 2830262.
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    242. Hadley JS, Fradin A, Murphy RC. Electron capture negative ion chemical ionization analysis of arachidonic acid. Biomed Environ Mass Spectrom. 1988 Feb 01; 15(3):175-8. PMID: 3130114.
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    243. Maclouf JA, Murphy RC. Transcellular metabolism of neutrophil-derived leukotriene A4 by human platelets. A potential cellular source of leukotriene C4. J Biol Chem. 1988 Jan 05; 263(1):174-81. PMID: 2826437.
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    244. Murphy RC, Stene DO. Oxidative metabolism of leukotriene E4 by rat hepatocytes. Ann N Y Acad Sci. 1988; 524:35-42. PMID: 2837969.
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    245. Westcott JY, Murphy RC, Stenmark K. Eicosanoids in human ventricular cerebrospinal fluid following severe brain injury. Prostaglandins. 1987 Dec; 34(6):877-87. PMID: 2835791.
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    246. Haroldsen PE, Murphy RC. Analysis of phospholipid molecular species in rat lung as dinitrobenzoate diglycerides by electron capture negative chemical ionization mass spectrometry. Biomed Environ Mass Spectrom. 1987 Oct; 14(10):573-8. PMID: 2962658.
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