Halden Scott
Title | Associate Professor |
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Institution | University of Colorado Denver - Anschutz Medical Campus |
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Department | SOM-PEDS |
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Email | |
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Research R18HS029786 (Scott, Halden F)Sep 30, 2023 - Jul 31, 2027 AHRQ The Right Call: Implementing a Sepsis Diagnostic Safety Toolkit in a Pediatric Transfer Call Center to Improve Diagnosis of Children in General Emergency Settings Role Description: Sepsis is a leading cause of death in children, and an early diagnosis that improves outcomes is less likely in children who are treated in general Emergency Departments (that treat adults and children) compared to pediatric Emergency Departments. In this study, we will adapt, implement, and evaluate tools that have improved diagnosis: a pediatric sepsis diagnostic checklist and diagnostic work system improvements to the consultation phone calls that occur among a general emergency physician, a transfer nurse, and a pediatric emergency physician. This research will improve early pediatric sepsis diagnosis in general EDs where most children receive their first critical hours of care, and it will identify approaches to improving diagnosis in that can be used in other high-risk conditions in emergency settings. Role: PI |
| R18HS029786 (SCOTT, HALDEN F)Sep 30, 2023 - Jul 31, 2027 NIH The Right Call: Implementing a Sepsis Diagnostic Safety Toolkit in a Pediatric Transfer Call Center to Improve Diagnosis of Children in General Emergency Settings Role: Principal Investigator |
| K08HS025696 (SCOTT, HALDEN F)Aug 1, 2018 - Jul 31, 2023 NIH Enhancing Quality in Pediatrics Sepsis with Shock Prediction and Early Electronic Decision Support (EQUIP with SPEED) Role: Principal Investigator |
Bibliographic
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Schlapbach LJ, Watson RS, Sorce LR, Argent AC, Menon K, Hall MW, Akech S, Albers DJ, Alpern ER, Balamuth F, Bembea M, Biban P, Carrol ED, Chiotos K, Chisti MJ, DeWitt PE, Evans I, Flauzino de Oliveira C, Horvat CM, Inwald D, Ishimine P, Jaramillo-Bustamante JC, Levin M, Lodha R, Martin B, Nadel S, Nakagawa S, Peters MJ, Randolph AG, Ranjit S, Rebull MN, Russell S, Scott HF, de Souza DC, Tissieres P, Weiss SL, Wiens MO, Wynn JL, Kissoon N, Zimmerman JJ, Sanchez-Pinto LN, Bennett TD. International Consensus Criteria for Pediatric Sepsis and Septic Shock. JAMA. 2024 02 27; 331(8):665-674. PMID: 38245889.
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Sanchez-Pinto LN, Bennett TD, DeWitt PE, Russell S, Rebull MN, Martin B, Akech S, Albers DJ, Alpern ER, Balamuth F, Bembea M, Chisti MJ, Evans I, Horvat CM, Jaramillo-Bustamante JC, Kissoon N, Menon K, Scott HF, Weiss SL, Wiens MO, Zimmerman JJ, Argent AC, Sorce LR, Schlapbach LJ, Watson RS, Biban P, Carrol E, Chiotos K, Flauzino De Oliveira C, Hall MW, Inwald D, Ishimine P, Levin M, Lodha R, Nadel S, Nakagawa S, Peters MJ, Randolph AG, Ranjit S, Souza DC, Tissieres P, Wynn JL. Development and Validation of the Phoenix Criteria for Pediatric Sepsis and Septic Shock. JAMA. 2024 02 27; 331(8):675-686. PMID: 38245897.
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Scott HF, Lindberg DM, Brackman S, McGonagle E, Leonard JE, Adelgais K, Bajaj L, Dillon M, Kempe A. Pediatric Sepsis in General Emergency Departments: Association Between Pediatric Sepsis Case Volume, Care Quality, and Outcome. Ann Emerg Med. 2024 Apr; 83(4):318-326. PMID: 38069968.
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Balamuth F, Scott HF. The Challenge of Identifying Sepsis in Children. Ann Emerg Med. 2023 10; 82(4):503-504. PMID: 37436345.
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Slatnick LR, Miller K, Scott HF, Loi M, Esbenshade AJ, Franklin A, Lee-Sherick AB. Serum lactate is associated with increased illness severity in immunocompromised pediatric hematology oncology patients presenting to the emergency department with fever. Front Oncol. 2022; 12:990279. PMID: 36276165.
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Scott HF, Kempe A, Bajaj L, Lindberg DM, Dafoe A, Dorsey Holliman B. "These Are Our Kids": Qualitative Interviews With Clinical Leaders in General Emergency Departments on Motivations, Processes, and Guidelines in Pediatric Sepsis Care. Ann Emerg Med. 2022 10; 80(4):347-357. PMID: 35840434.
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Balamuth F, Scott HF, Weiss SL, Webb M, Chamberlain JM, Bajaj L, Depinet H, Grundmeier RW, Campos D, Deakyne Davies SJ, Simon NJ, Cook LJ, Alpern ER. Validation of the Pediatric Sequential Organ Failure Assessment Score and Evaluation of Third International Consensus Definitions for Sepsis and Septic Shock Definitions in the Pediatric Emergency Department. JAMA Pediatr. 2022 07 01; 176(7):672-678. PMID: 35575803.
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Eisenberg MA, Riggs R, Paul R, Balamuth F, Richardson T, DeSouza HG, Abbadesa MK, DeMartini TKM, Frizzola M, Lane R, Lloyd J, Melendez E, Patankar N, Rutman L, Sebring A, Timmons Z, Scott HF. Association Between the First-Hour Intravenous Fluid Volume and Mortality in Pediatric Septic Shock. Ann Emerg Med. 2022 09; 80(3):213-224. PMID: 35641356.
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Menon K, Schlapbach LJ, Akech S, Argent A, Biban P, Carrol ED, Chiotos K, Jobayer Chisti M, Evans IVR, Inwald DP, Ishimine P, Kissoon N, Lodha R, Nadel S, Oliveira CF, Peters M, Sadeghirad B, Scott HF, de Souza DC, Tissieres P, Watson RS, Wiens MO, Wynn JL, Zimmerman JJ, Sorce LR. Criteria for Pediatric Sepsis-A Systematic Review and Meta-Analysis by the Pediatric Sepsis Definition Taskforce. Crit Care Med. 2022 01 01; 50(1):21-36. PMID: 34612847.
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Greenwald E, Olds E, Leonard J, Deakyne Davies SJ, Brant J, Scott HF. Pediatric Sepsis in Community Emergency Care Settings: Guideline Concordance and Outcomes. Pediatr Emerg Care. 2021 Dec 01; 37(12):e1571-e1577. PMID: 32941361.
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Stenson EK, You Z, Reeder R, Norris J, Scott HF, Dixon BP, Thurman JM, Frazer-Abel A, Mourani P, Kendrick J. Complement Activation Fragments Are Increased in Critically Ill Pediatric Patients with Severe AKI. Kidney360. 2021 12 30; 2(12):1884-1891. PMID: 35419539.
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Lockwood JM, Scott HF, Wathen B, Rolison E, Smith C, Bundy J, Swanson A, Nickels S, Bakel LA, Bajaj L. An Acute Care Sepsis Response System Targeting Improved Antibiotic Administration. Hosp Pediatr. 2021 09; 11(9):944-955. PMID: 34404744.
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Nathaniel ED, Scott HF, Wathen B, Schmidt SK, Rolison E, Smith C, Hays MJ, Lockwood JM. Confidence-weighted Testing as an Impactful Education Intervention within a Pediatric Sepsis Quality Improvement Initiative. Pediatr Qual Saf. 2021 Sep-Oct; 6(5):e460. PMID: 34476312.
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Scott HF, Bennett TD. Automated emergency department sepsis screening appears superior to manual screening. J Pediatr. 2021 07; 234:286-288. PMID: 34172164.
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Daymont C, Balamuth F, Scott HF, Bonafide CP, Brady PW, Depinet H, Alpern ER. Elevated Heart Rate and Risk of Revisit With Admission in Pediatric Emergency Patients. Pediatr Emerg Care. 2021 Apr 01; 37(4):e185-e191. PMID: 30020247.
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Scott HF, Colborn KL, Sevick CJ, Bajaj L, Deakyne Davies SJ, Fairclough D, Kissoon N, Kempe A. Development and Validation of a Model to Predict Pediatric Septic Shock Using Data Known 2 Hours After Hospital Arrival. Pediatr Crit Care Med. 2021 01 01; 22(1):16-26. PMID: 33060422.
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Larsen GY, Brilli R, Macias CG, Niedner M, Auletta JJ, Balamuth F, Campbell D, Depinet H, Frizzola M, Hueschen L, Lowerre T, Mack E, Paul R, Razzaqi F, Schafer M, Scott HF, Silver P, Wathen B, Lukasiewicz G, Stuart J, Riggs R, Richardson T, Ward L, Huskins WC. Development of a Quality Improvement Learning Collaborative to Improve Pediatric Sepsis Outcomes. Pediatrics. 2021 01; 147(1). PMID: 33328337.
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Scott HF, Brilli RJ, Paul R, Macias CG, Niedner M, Depinet H, Richardson T, Riggs R, Gruhler H, Larsen GY, Huskins WC, Balamuth F. Evaluating Pediatric Sepsis Definitions Designed for Electronic Health Record Extraction and Multicenter Quality Improvement. Crit Care Med. 2020 10; 48(10):e916-e926. PMID: 32931197.
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Balamuth F, Alpern ER, Scott HF. The Need for Risk Stratification Tools in the Pediatric Emergency Department. Pediatrics. 2020 10; 146(4). PMID: 32978293.
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Scott HF, Balamuth F, Alpern ER. The Legacy of Pediatric Sepsis State Legislation. Pediatrics. 2020 07; 146(1). PMID: 32605993.
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Slatnick LR, Thornhill D, Deakyne Davies SJ, Ford JB, Scott HF, Manco-Johnson MJ, Warren BB. Disseminated Intravascular Coagulation Is an Independent Predictor of Adverse Outcomes in Children in the Emergency Department with Suspected Sepsis. J Pediatr. 2020 10; 225:198-206.e2. PMID: 32553867.
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Weiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, M?ller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children. Pediatr Crit Care Med. 2020 02; 21(2):e52-e106. PMID: 32032273.
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Weiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, M?ller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Executive summary: surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children. Intensive Care Med. 2020 02; 46(Suppl 1):1-9. PMID: 32030528.
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Weiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, M?ller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children. Intensive Care Med. 2020 02; 46(Suppl 1):10-67. PMID: 32030529.
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Weiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, M?ller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Executive Summary: Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children. Pediatr Crit Care Med. 2020 02; 21(2):186-195. PMID: 32032264.
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Scott HF, Kempe A, Deakyne Davies SJ, Krack P, Leonard J, Rolison E, Mackenzie J, Wathen B, Bajaj L. Managing Diagnostic Uncertainty in Pediatric Sepsis Quality Improvement with a Two-Tiered Approach. Pediatr Qual Saf. 2020 Jan-Feb; 5(1):e244. PMID: 32766482.
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Scott HF, Colborn KL, Sevick CJ, Bajaj L, Kissoon N, Deakyne Davies SJ, Kempe A. Development and Validation of a Predictive Model of the Risk of Pediatric Septic Shock Using Data Known at the Time of Hospital Arrival. J Pediatr. 2020 02; 217:145-151.e6. PMID: 31733815.
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Scott HF. Thiamine in Pediatric Sepsis: A Motivating Study. Pediatr Crit Care Med. 2019 09; 20(9):903-904. PMID: 31483388.
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Scott HF, Balamuth F, Paul RM. Sepsis Bundles and Mortality Among Pediatric Patients. JAMA. 2018 12 04; 320(21):2271. PMID: 30512094.
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Schmidt SK, Brou L, Deakyne SJ, Mistry RD, Scott HF. Frequency and Characterization of Tracheal Intubation Adverse Events in Pediatric Sepsis. Pediatr Crit Care Med. 2018 02; 19(2):e80-e87. PMID: 29194282.
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Scott HF, Greenwald EE, Bajaj L, Deakyne Davies SJ, Brou L, Kempe A. The Sensitivity of Clinician Diagnosis of Sepsis in Tertiary and Community-Based Emergency Settings. J Pediatr. 2018 04; 195:220-227.e1. PMID: 29395173.
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McIntosh AM, Davidson JA, Scott HF. The authors reply. Pediatr Crit Care Med. 2017 10; 18(10):1003-1005. PMID: 28976472.
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Spruiell MD, Searns JB, Heare TC, Roberts JL, Wylie E, Pyle L, Donaldson N, Stewart JR, Heizer H, Reese J, Scott HF, Pearce K, Anderson CJ, Erickson M, Parker SK. Clinical Care Guideline for Improving Pediatric Acute Musculoskeletal Infection Outcomes. J Pediatric Infect Dis Soc. 2017 Sep 01; 6(3):e86-e93. PMID: 28419275.
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Davis AL, Carcillo JA, Aneja RK, Deymann AJ, Lin JC, Nguyen TC, Okhuysen-Cawley RS, Relvas MS, Rozenfeld RA, Skippen PW, Stojadinovic BJ, Williams EA, Yeh TS, Balamuth F, Brierley J, de Caen AR, Cheifetz IM, Choong K, Conway E, Cornell T, Doctor A, Dugas MA, Feldman JD, Fitzgerald JC, Flori HR, Fortenberry JD, Graciano AL, Greenwald BM, Hall MW, Han YY, Hernan LJ, Irazuzta JE, Iselin E, van der Jagt EW, Jeffries HE, Kache S, Katyal C, Kissoon N, Kon AA, Kutko MC, MacLaren G, Maul T, Mehta R, Odetola F, Parbuoni K, Paul R, Peters MJ, Ranjit S, Reuter-Rice KE, Schnitzler EJ, Scott HF, Torres A, Weingarten-Abrams J, Weiss SL, Zimmerman JJ, Zuckerberg AL. The American College of Critical Care Medicine Clinical Practice Parameters for Hemodynamic Support of Pediatric and Neonatal Septic Shock: Executive Summary. Pediatr Crit Care Med. 2017 09; 18(9):884-890. PMID: 28723883.
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Scott HF, Kempe A, Bajaj L. Venous vs Arterial Lactate and 30-Day Mortality in Pediatric Sepsis-Reply. JAMA Pediatr. 2017 08 01; 171(8):813-814. PMID: 28655033.
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McIntosh AM, Tong S, Deakyne SJ, Davidson JA, Scott HF. Validation of the Vasoactive-Inotropic Score in Pediatric Sepsis. Pediatr Crit Care Med. 2017 Aug; 18(8):750-757. PMID: 28486385.
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Davis AL, Carcillo JA, Aneja RK, Deymann AJ, Lin JC, Nguyen TC, Okhuysen-Cawley RS, Relvas MS, Rozenfeld RA, Skippen PW, Stojadinovic BJ, Williams EA, Yeh TS, Balamuth F, Brierley J, de Caen AR, Cheifetz IM, Choong K, Conway E, Cornell T, Doctor A, Dugas MA, Feldman JD, Fitzgerald JC, Flori HR, Fortenberry JD, Graciano AL, Greenwald BM, Hall MW, Han YY, Hernan LJ, Irazuzta JE, Iselin E, van der Jagt EW, Jeffries HE, Kache S, Katyal C, Kissoon N, Kon AA, Kutko MC, MacLaren G, Maul T, Mehta R, Odetola F, Parbuoni K, Paul R, Peters MJ, Ranjit S, Reuter-Rice KE, Schnitzler EJ, Scott HF, Torres A, Weingarten-Arams J, Weiss SL, Zimmerman JJ, Zuckerberg AL. American College of Critical Care Medicine Clinical Practice Parameters for Hemodynamic Support of Pediatric and Neonatal Septic Shock. Crit Care Med. 2017 06; 45(6):1061-1093. PMID: 28509730.
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Scott HF, Brou L, Deakyne SJ, Kempe A, Fairclough DL, Bajaj L. Association Between Early Lactate Levels and 30-Day Mortality in Clinically Suspected Sepsis in Children. JAMA Pediatr. 2017 03 01; 171(3):249-255. PMID: 28068437.
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Scott HF, Brou L, Deakyne SJ, Fairclough DL, Kempe A, Bajaj L. Lactate Clearance and Normalization and Prolonged Organ Dysfunction in Pediatric Sepsis. J Pediatr. 2016 Mar; 170:149-55.e1-4. PMID: 26711848.
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Scott HF, Paul R, Balamuth F. The Spectrum of Pediatric Sepsis: "Septicemia" Misses Severe Cases. Ann Emerg Med. 2015 Dec; 66(6):685-6. PMID: 26590745.
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de Caen AR, Berg MD, Chameides L, Gooden CK, Hickey RW, Scott HF, Sutton RM, Tijssen JA, Topjian A, van der Jagt ?W, Schexnayder SM, Samson RA. Part 12: Pediatric Advanced Life Support: 2015 American Heart Association Guidelines Update for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation. 2015 Nov 03; 132(18 Suppl 2):S526-42. PMID: 26473000.
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Balamuth F, Weiss SL, Hall M, Neuman MI, Scott H, Brady PW, Paul R, Farris RW, McClead R, Centkowski S, Baumer-Mouradian S, Weiser J, Hayes K, Shah SS, Alpern ER. Identifying Pediatric Severe Sepsis and Septic Shock: Accuracy of Diagnosis Codes. J Pediatr. 2015 Dec; 167(6):1295-300.e4. PMID: 26470685.
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Chiotos K, Balamuth F, Scott HF. Management of bacterial severe sepsis and septic shock. J Pediatr Intensive Care. 2014 Dec; 3(4):227-242. PMID: 31214470.
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Scott HF, Deakyne SJ, Woods JM, Bajaj L. The prevalence and diagnostic utility of systemic inflammatory response syndrome vital signs in a pediatric emergency department. Acad Emerg Med. 2015 Apr; 22(4):381-9. PMID: 25778743.
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Scott HF, Donoghue AJ, Gaieski DF, Marchese RF, Mistry RD. Effectiveness of physical exam signs for early detection of critical illness in pediatric systemic inflammatory response syndrome. BMC Emerg Med. 2014 Nov 19; 14:24. PMID: 25407007.
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Scott HF, Donoghue AJ, Gaieski DF, Marchese RF, Mistry RD. The utility of early lactate testing in undifferentiated pediatric systemic inflammatory response syndrome. Acad Emerg Med. 2012 Nov; 19(11):1276-80. PMID: 23167859.
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Scott H, Melendez E, Cruz AT. Mortality after fluid bolus in African children with sepsis. N Engl J Med. 2011 10 06; 365(14):1350-1; author reply 1351-3. PMID: 21991965.
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Mistry RD, Scott HF, Zaoutis TE, Alpern ER. Emergency department treatment failures for skin infections in the era of community-acquired methicillin-resistant Staphylococcus aureus. Pediatr Emerg Care. 2011 Jan; 27(1):21-6. PMID: 21178810.
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Mistry RD, Scott HF, Alpern ER, Zaoutis TE. Prevalence of Proteus mirabilis in skin abscesses of the axilla. J Pediatr. 2010 May; 156(5):850-1. PMID: 20303504.
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Mistry RD, Weisz K, Scott HF, Alpern ER. Emergency management of pediatric skin and soft tissue infections in the community-associated methicillin-resistant Staphylococcus aureus era. Acad Emerg Med. 2010 Feb; 17(2):187-93. PMID: 20370748.
This graph shows the total number of publications by year, by first, middle/unknown, or last author.
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Year | Publications |
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2010 | 2 | 2011 | 2 | 2012 | 1 | 2014 | 1 | 2015 | 6 | 2017 | 7 | 2018 | 3 | 2019 | 2 | 2020 | 10 | 2021 | 7 | 2022 | 5 | 2023 | 2 | 2024 | 2 |
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