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Duy T Nguyen

TitleAssociate Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-MED
Phone720/848-0758

    Collapse Overview 
    Collapse overview
    I have research projects, both clinical and translational, evaluating the treatment of cardiac arrhythmias, particularly atrial fibrillation and ventricular tachycardia. I have concentrated on studying the mechanisms and physiology of biomedical and clinical problems that could then be utilized in translational research for the treatment of these arrhythmias in a variety of populations, including adult congenital heart disease. The long-term goals of my translational research are to evaluate novel radiofrequency (RF) ablation strategies, catheter designs to improve procedural efficacy and safety outcomes, and molecular targets to enhance RF ablation of atrial fibrillation and ventricular tachycardia. We have published studies on how metallic and nonmetallic nanoparticles may be utilized to facilitate therapeutic ablation applications in arrhythmia management. We have evaluated multiple ablation catheter designs as well as ablation strategies to improve safety and maximize RF delivery during ablation for atrial fibrillation. We have both in vivo and ex vivo animal models of atrial and ventricular arrhythmias. With an emphasis on clinical electrophysiology and research applications, I have conducted and published on clinical and translational research related to atrial fibrillation and VT, from the bench to the bedside. Fellows are integral to these projects, and I have worked with dozens of fellows over the years, all of whom have been successful in achieving first author presentations at cardiology meetings and first author manuscripts. I will be serving as a cardiology mentor for the 2018-2019 academic year.


    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Kollengode M, Mathew J, Yeung E, Sauer WH, Nguyen DT. Successful atrial fibrillation ablation without pulmonary vein isolation utilizing focal impulse and rotor mapping in an atriopulmonary Fontan. HeartRhythm Case Rep. 2018 Jun; 4(6):241-246. PMID: 29922583.
      View in: PubMed
    2. Nguyen DT, Zipse M, Borne RT, Zheng L, Tzou WS, Sauer WH. Use of Tissue Electric and Ultrasound Characteristics to Predict and Prevent Steam-Generated Cavitation During High-Power Radiofrequency Ablation. JACC Clin Electrophysiol. 2018 Apr; 4(4):491-500. PMID: 30067489.
      View in: PubMed
    3. Nguyen DT, Gerstenfeld EP, Tzou WS, Jurgens PT, Zheng L, Schuller J, Zipse M, Sauer WH. Radiofrequency Ablation Using an Open Irrigated Electrode Cooled With Half-Normal Saline. JACC Clin Electrophysiol. 2017 Oct; 3(10):1103-1110. PMID: 29759492.
      View in: PubMed
    4. Borne RT, Kay J, Fagan T, Nguyen DT. Intra-atrial Reentrant Tachycardia in Complete Transposition of the Great Arteries Without Femoral Venous Access. Card Electrophysiol Clin. 2016 Mar; 8(1):197-200. PMID: 26920194.
      View in: PubMed
    5. Zipse MM, Nguyen DT. Ablation of Atrial Fibrillation in a Patient with a Mechanical Mitral Valve. Card Electrophysiol Clin. 2016 Mar; 8(1):155-9. PMID: 26920185.
      View in: PubMed
    6. Ruckdeschel ES, Schuller J, Nguyen DT. Ventricular Tachycardia in Congenital Pulmonary Stenosis. Card Electrophysiol Clin. 2016 Mar; 8(1):205-9. PMID: 26920196.
      View in: PubMed
    7. Ruckdeschel ES, Kay J, Varosy P, Nguyen DT. Slow Pathway Modification in a Patient with D-Transposition of the Great Arteries and Atrial Switch Procedure. Card Electrophysiol Clin. 2016 Mar; 8(1):191-6. PMID: 26920193.
      View in: PubMed
    8. Gonzalez JE, Tzou W, Sauer WH, Nguyen DT. Ventricular Tachycardia in a Patient with Biventricular Noncompaction. Card Electrophysiol Clin. 2016 Mar; 8(1):139-44. PMID: 26920182.
      View in: PubMed
    9. Zipse MM, Groves DW, Khanna AD, Nguyen DT. An Approach to Endovascular Ventricular Pacing in a Patient with Ebstein Anomaly and a Mechanical Tricuspid Valve. Card Electrophysiol Clin. 2016 Mar; 8(1):169-71. PMID: 26920188.
      View in: PubMed
    10. Ruckdeschel ES, Kay J, Sauer WH, Nguyen DT. Atrial Fibrillation Ablation Without Pulmonary Vein Isolation in a Patient with Fontan Palliation. Card Electrophysiol Clin. 2016 Mar; 8(1):161-4. PMID: 26920186.
      View in: PubMed
    11. Ruckdeschel ES, Wolfel E, Nguyen DT. A Case of Cough-induced Ventricular Tachycardia in a Patient with a Left Ventricular Assist Device. Card Electrophysiol Clin. 2016 Mar; 8(1):165-7. PMID: 26920187.
      View in: PubMed
    12. Gonzalez JE, Zipse MM, Nguyen DT, Sauer WH. Antidromic Atrioventricular Reciprocating Tachycardia Using a Concealed Retrograde Conducting Left Lateral Accessory Pathway. Card Electrophysiol Clin. 2016 Mar; 8(1):37-43. PMID: 26920167.
      View in: PubMed
    13. Gonzalez JE, Nguyen DT. Supraventricular Tachycardia in a Patient with an Interrupted Inferior Vena Cava. Card Electrophysiol Clin. 2016 Mar; 8(1):45-50. PMID: 26920168.
      View in: PubMed
    14. Zipse MM, Schuller JL, Steckman DS, Katz DF, Tzou WS, Nguyen DT, Aleong RG, Sung RK, Tompkins C, Varosy PD, Sauer WH. Measured Lead Parameters and Electrogram Sensing Over Time in Patients With Cardiac Sarcoidosis and an Implanted Cardiac-Defibrillator. JACC Clin Electrophysiol. 2015 Mar - Apr; 1(1-2):94-102. PMID: 29759346.
      View in: PubMed
    15. Schuller JL, Varosy PD, Nguyen DT. Diagnostic value of adenosine conversion of wide complex tachycardia-reply. JAMA Intern Med. 2014 Oct; 174(10):1706. PMID: 25285738.
      View in: PubMed
    16. Zipse MM, Sauer WH, Varosy PD, Aleong RG, Nguyen DT. Inappropriate shocks due to subcutaneous air in a patient with a subcutaneous cardiac defibrillator. Circ Arrhythm Electrophysiol. 2014 Aug; 7(4):768-70. PMID: 25140025.
      View in: PubMed
    17. Steckman DA, Nguyen DT, Sauer WH. Catheter ablation of atrial fibrillation and left atrial flutter in a patient with a left atrial appendage occlusion device. Europace. 2014 May; 16(5):651. PMID: 24591678.
      View in: PubMed
    18. Heath R, Kay J, Nguyen DT. Atrial flutter ablation in a patient with Marfanoid syndrome and anomalous cavotricuspid isthmus. Europace. 2014 Jul; 16(7):1006. PMID: 24473500.
      View in: PubMed
    19. Mestroni L, Nguyen DT. Inhibition of proto-oncogene c-Src tyrosine kinase: toward a new antiarrhythmic strategy? J Am Coll Cardiol. 2014 Mar 11; 63(9):935-7. PMID: 24412447; PMCID: PMC4469261.
    20. Ruckdeschel ES, Quaife R, Lewkowiez L, Kay J, Sauer WH, Collins KK, Nguyen DT. Preprocedural imaging in patients with transposition of the great arteries facilitates placement of cardiac resynchronization therapy leads. Pacing Clin Electrophysiol. 2014 May; 37(5):546-53. PMID: 24313876.
      View in: PubMed
    21. Nguyen DT, Sauer WH. Durable Pulmonary Vein Isolation: The Holy Grail of Atrial Fibrillation Ablation. J Atr Fibrillation. 2013 Oct-Nov; 6(3):927. PMID: 28496898.
      View in: PubMed
    22. Schuller JL, Varosy PD, Nguyen DT. Wide complex tachycardia and adenosine. JAMA Intern Med. 2013 Sep 23; 173(17):1644-6. PMID: 23897223.
      View in: PubMed
    23. Chen A, Sauer W, Nguyen DT. A dire reaction: rash after amiodarone administration. Am J Med. 2013 Apr; 126(4):301-3. PMID: 23507205.
      View in: PubMed
    24. Tzou WS, Nguyen DT, Aleong RG, Varosy PD, Katz DF, Heath RR, Schuller JL, Lowery CM, Lewkowiez L, Sauer WH. Endocardial electrogram characteristics of epicardial ventricular arrhythmias. J Cardiovasc Electrophysiol. 2013 Jun; 24(6):649-54. PMID: 23397974.
      View in: PubMed
    25. Nguyen DT, Gupta R, Kay J, Fagan T, Lowery C, Collins KK, Sauer WH. Percutaneous transhepatic access for catheter ablation of cardiac arrhythmias. Europace. 2013 Apr; 15(4):494-500. PMID: 23385049.
      View in: PubMed
    26. Schuller JL, Zipse M, Crawford T, Bogun F, Beshai J, Patel AR, Sweiss NJ, Nguyen DT, Aleong RG, Varosy PD, Weinberger HD, Sauer WH. Implantable cardioverter defibrillator therapy in patients with cardiac sarcoidosis. J Cardiovasc Electrophysiol. 2012 Sep; 23(9):925-9. PMID: 22812589.
      View in: PubMed
    27. Steckman DA, Schneider PM, Schuller JL, Aleong RG, Nguyen DT, Sinagra G, Vitrella G, Brun F, Cova MA, Pagnan L, Mestroni L, Varosy PD, Sauer WH. Utility of cardiac magnetic resonance imaging to differentiate cardiac sarcoidosis from arrhythmogenic right ventricular cardiomyopathy. Am J Cardiol. 2012 Aug 15; 110(4):575-9. PMID: 22595349.
      View in: PubMed
    28. Heath R, Sauer WH, Aleong R, Nguyen DT. Tachycardia-induced tachycardia. J Cardiovasc Electrophysiol. 2012 Dec; 23(12):1390-2. PMID: 22587399.
      View in: PubMed
    29. Nguyen DT, Heath R, Ambardekar A, Sauer W. Acquired premature ventricular ectopy after cardiac transplantation. J Heart Lung Transplant. 2012 Jul; 31(7):787-8. PMID: 22503376.
      View in: PubMed
    30. Katz DF, Varosy PD, Nguyen DT, Schuller JL, Aleong RG, Heath RR, Sauer WH. The irregular tachycardia that was not atrial fibrillation. Arch Intern Med. 2011 Dec 12; 171(22):1985-8. PMID: 22158570.
      View in: PubMed
    31. Zalkind D, Aleong R, Sauer W, Nguyen DT. Unusual fibrillation in the emergency department after fall. Circulation. 2011 Jun 28; 123(25):e641-2. PMID: 21709067.
      View in: PubMed
    32. Heath RR, Schuller JL, Sauer WH, Varosy PD, Nguyen DT, Aleong RG. Images in cardiovascular medicine: a mobile tubular mass visualized by transesophageal echocardiography after successful lead extraction. Circulation. 2011 May 17; 123(19):e590-1. PMID: 21576675.
      View in: PubMed
    33. Heath RR, Varosy PD, Katz DF, Schuller JL, Aleong RG, Sauer WH, Nguyen DT. Life-threatening ST-segment elevation without coronary artery disease. Arch Intern Med. 2011 May 09; 171(9):801, 802-3. PMID: 21555657.
      View in: PubMed
    34. Nguyen DT, Wang ZJ, Vedantham V, Badhwar N. Images in cardiovascular medicine. Odynophagia after atrial fibrillation ablation. Circulation. 2011 Mar 01; 123(8):e253-4. PMID: 21357841.
      View in: PubMed
    35. Nguyen DT, Scheinman M, Olgin J, Badhwar N. Wenckebach during supraventricular tachycardia. Circ Arrhythm Electrophysiol. 2010 Dec; 3(6):671-3. PMID: 21156779.
      View in: PubMed
    36. Nguyen DT, Scheinman M, Badhwar N. Supraventricular tachycardia with no ventriculoatrial conduction: what is the mechanism? J Cardiovasc Electrophysiol. 2010 Dec; 21(12):1419-20. PMID: 20653810.
      View in: PubMed
    37. Nguyen DT, Lee R, Tseng ZH. Supraventricular Tachycardia After Atrial Fibrillation Ablation. Card Electrophysiol Clin. 2010 Jun; 2(2):313-316. PMID: 28770772.
      View in: PubMed
    38. Nguyen DT, Tseng ZH, Lee BK, Badhwar N. Ventricular Tachycardia After Implantable Cardioverter-Defibrillator Placement. Card Electrophysiol Clin. 2010 Jun; 2(2):277-280. PMID: 28770763.
      View in: PubMed
    39. Nguyen DT, Marcus GM. A Case of Atrial Arrhythmia After Lung Transplant. Card Electrophysiol Clin. 2010 Jun; 2(2):295-298. PMID: 28770768.
      View in: PubMed
    40. Nguyen DT, Scheinman M. Supraventricular Tachycardia in Pulmonary Hypertension. Card Electrophysiol Clin. 2010 Jun; 2(2):317-319. PMID: 28770773.
      View in: PubMed
    41. Nguyen DT, Badhwar N. Supraventricular Tachycardia and Atrioventricular Block. Card Electrophysiol Clin. 2010 Jun; 2(2):235-238. PMID: 28770757.
      View in: PubMed
    42. Nguyen DT, Scheinman M, Badhwar N. Supraventricular tachycardia with alternating cycle lengths: what is the mechanism? Heart Rhythm. 2011 Mar; 8(3):478-9. PMID: 20434588.
      View in: PubMed
    43. Kimura BJ, Fowler SJ, Nguyen DT, Amundson SA, DeMaria AN. Detection of early carotid arterial atherosclerosis by briefly trained physicians using a hand-held ultrasound device. Am J Cardiol. 2003 Jul 15; 92(2):239-40. PMID: 12860236.
      View in: PubMed
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