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Yogendra H Raol

TitleAssociate Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus

    Collapse Research 
    Collapse research activities and funding
    R01HD065534     (RAOL, YOGENDRA H)Jul 15, 2011 - Apr 30, 2015
    Efficacy of flupirtine for treatment of neonatal hypoxic-ischemic encephalopathy
    Role: Principal Investigator

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Patil MA, Matter BA, Raol YH, Bourne DWA, Kelley RA, Kompella UB. Brain Distribution and Metabolism of Flupirtine, a Nonopioid Analgesic Drug with Antiseizure Effects, in Neonatal Rats. Pharmaceutics. 2018 Dec 16; 10(4). PMID: 30558371.
      View in: PubMed
    2. Akman O, Raol YH, Auvin S, Cortez MA, Kubova H, de Curtis M, Ikeda A, Dudek FE, Galanopoulou AS. Methodologic recommendations and possible interpretations of video-EEG recordings in immature rodents used as experimental controls: A TASK1-WG2 report of the ILAE/AES Joint Translational Task Force. Epilepsia Open. 2018 Dec; 3(4):437-459. PMID: 30525114.
      View in: PubMed
    3. Sampath D, Valdez R, White AM, Raol YH. Anticonvulsant effect of flupirtine in an animal model of neonatal hypoxic-ischemic encephalopathy. Neuropharmacology. 2017 Sep 01; 123:126-135. PMID: 28587899.
      View in: PubMed
    4. Weitzel LR, Sampath D, Shimizu K, White AM, Herson PS, Raol YH. EEG power as a biomarker to predict the outcome after cardiac arrest and cardiopulmonary resuscitation induced global ischemia. Life Sci. 2016 Nov 15; 165:21-25. PMID: 27640888.
      View in: PubMed
    5. Sampath D, Shmueli D, White AM, Raol YH. Flupirtine effectively prevents development of acute neonatal seizures in an animal model of global hypoxia. Neurosci Lett. 2015 Oct 21; 607:46-51. PMID: 26365409; PMCID: PMC4631640 [Available on 10/21/16].
    6. Grabenstatter HL, Cogswell M, Cruz Del Angel Y, Carlsen J, Gonzalez MI, Raol YH, Russek SJ, Brooks-Kayal AR. Effect of spontaneous seizures on GABAA receptor a4 subunit expression in an animal model of temporal lobe epilepsy. Epilepsia. 2014 Nov; 55(11):1826-33. PMID: 25223733; PMCID: PMC4596257.
    7. Sampath D, White AM, Raol YH. Characterization of neonatal seizures in an animal model of hypoxic-ischemic encephalopathy. Epilepsia. 2014 Jul; 55(7):985-93. PMID: 24836645; PMCID: PMC4107002.
    8. Miller JA, Kirkley KA, Padmanabhan R, Liang LP, Raol YH, Patel M, Bialecki RA, Tjalkens RB. Repeated exposure to low doses of kainic acid activates nuclear factor kappa B (NF-?B) prior to seizure in transgenic NF-?B/EGFP reporter mice. Neurotoxicology. 2014 Sep; 44:39-47. PMID: 24813937.
      View in: PubMed
    9. Grabenstatter HL, Carlsen J, Raol YH, Yang T, Hund D, Cruz Del Angel Y, White AM, Gonzalez MI, Longo FM, Russek SJ, Brooks-Kayal AR. Acute administration of the small-molecule p75(NTR) ligand does not prevent hippocampal neuron loss or development of spontaneous seizures after pilocarpine-induced status epilepticus. J Neurosci Res. 2014 Oct; 92(10):1307-18. PMID: 24801281; PMCID: PMC4134742.
    10. Clark AM, Mondick JT, Cloyd JC, Zuppa AF, Raol YH, Clancy RR. Plasma topiramate concentrations resulting from doses associated with neuroprotection against white matter injury and stroke in two strains of rat pups. Pediatr Res. 2013 Mar; 73(3):317-24. PMID: 23254278.
      View in: PubMed
    11. Noam Y, Raol YH, Holmes GL. Searching for new targets for treatment of pediatric epilepsy. Epilepsy Behav. 2013 Mar; 26(3):253-60. PMID: 23219411; PMCID: PMC3595393.
    12. Chapman KE, Raol YH, Brooks-Kayal A. Neonatal seizures: controversies and challenges in translating new therapies from the lab to the isolette. Eur J Neurosci. 2012 Jun; 35(12):1857-65. PMID: 22708596; PMCID: PMC3383637.
    13. Raol YH, Brooks-Kayal AR. Experimental models of seizures and epilepsies. Prog Mol Biol Transl Sci. 2012; 105:57-82. PMID: 22137429.
      View in: PubMed
    14. Brooks-Kayal AR, Raol YH, Russek SJ. Alteration of epileptogenesis genes. Neurotherapeutics. 2009 Apr; 6(2):312-8. PMID: 19332325; PMCID: PMC2700027.
    15. Raol YH, Lapides DA, Keating JG, Brooks-Kayal AR, Cooper EC. A KCNQ channel opener for experimental neonatal seizures and status epilepticus. Ann Neurol. 2009 Mar; 65(3):326-36. PMID: 19334075; PMCID: PMC2666110.
    16. Lund IV, Hu Y, Raol YH, Benham RS, Faris R, Russek SJ, Brooks-Kayal AR. BDNF selectively regulates GABAA receptor transcription by activation of the JAK/STAT pathway. Sci Signal. 2008 Oct 14; 1(41):ra9. PMID: 18922788; PMCID: PMC2651003.
    17. Raol YH, Lund IV, Bandyopadhyay S, Zhang G, Roberts DS, Wolfe JH, Russek SJ, Brooks-Kayal AR. Enhancing GABA(A) receptor alpha 1 subunit levels in hippocampal dentate gyrus inhibits epilepsy development in an animal model of temporal lobe epilepsy. J Neurosci. 2006 Nov 01; 26(44):11342-6. PMID: 17079662.
      View in: PubMed
    18. Raol YH, Zhang G, Lund IV, Porter BE, Maronski MA, Brooks-Kayal AR. Increased GABA(A)-receptor alpha1-subunit expression in hippocampal dentate gyrus after early-life status epilepticus. Epilepsia. 2006 Oct; 47(10):1665-73. PMID: 17054689.
      View in: PubMed
    19. Frye CA, Rhodes ME, Raol YH, Brooks-Kayal AR. Early postnatal stimulation alters pregnane neurosteroids in the hippocampus. Psychopharmacology (Berl). 2006 Jun; 186(3):343-50. PMID: 16491430; PMCID: PMC3608213.
    20. Roberts DS, Raol YH, Bandyopadhyay S, Lund IV, Budreck EC, Passini MA, Passini MJ, Wolfe JH, Brooks-Kayal AR, Russek SJ. Egr3 stimulation of GABRA4 promoter activity as a mechanism for seizure-induced up-regulation of GABA(A) receptor alpha4 subunit expression. Proc Natl Acad Sci U S A. 2005 Aug 16; 102(33):11894-9. PMID: 16091474; PMCID: PMC1187961.
    21. Porter BE, Zhang G, Celix J, Hsu FC, Raol YH, Telfeian A, Gallagher PR, Coulter DA, Brooks-Kayal AR. Heterogeneous GABAA receptor subunit expression in pediatric epilepsy patients. Neurobiol Dis. 2005 Apr; 18(3):484-91. PMID: 15755675.
      View in: PubMed
    22. Raol YH, Zhang G, Budreck EC, Brooks-Kayal AR. Long-term effects of diazepam and phenobarbital treatment during development on GABA receptors, transporters and glutamic acid decarboxylase. Neuroscience. 2005; 132(2):399-407. PMID: 15802192.
      View in: PubMed
    23. Zhang G, Raol YH, Hsu FC, Coulter DA, Brooks-Kayal AR. Effects of status epilepticus on hippocampal GABAA receptors are age-dependent. Neuroscience. 2004; 125(2):299-303. PMID: 15062973; PMCID: PMC2441871.
    24. Raol YH, Lynch DR, Brooks-Kayal AR. Role of excitatory amino acids in developmental epilepsies. Ment Retard Dev Disabil Res Rev. 2001; 7(4):254-60. PMID: 11754519.
      View in: PubMed
    25. Raol YH, Meti BL. Effects of vigabatrin on sleep-wakefulness cycle in amygdala-kindled rats. Epilepsia. 2000 Feb; 41(2):128-31. PMID: 10691108.
      View in: PubMed
    26. Raol YH, Meti BL. Sleep-wakefulness alterations in amygdala-kindled rats. Epilepsia. 1998 Nov; 39(11):1133-7. PMID: 9821976.
      View in: PubMed
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