Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Last Name
Institution

Christopher O. Hoyte

TitleProfessor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-EM MED Clinical
Phone720/848-6777

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Herzel B, Batavia N, Gavaza P, Phan T, Samones E, Ruha AM, Furmaga J, Hoyte C, Wolk BJ. The Cost of Antivenom: A Cost Minimization Study using the North American Snakebite Registry. J Med Toxicol. 2025 Apr 14. PMID: 40227519.
      View in: PubMed
    2. Ruha AM, Spyres MB, Culbreth R, Wolk B, Hoyte C, Campleman S. Systemic toxicity after rattlesnake envenomation in patients using angiotensin converting enzyme inhibitors: A North American Snakebite Registry study. Toxicon. 2025 Apr; 258:108292. PMID: 40054781.
      View in: PubMed
    3. Muschler K, Muschalek R, Hoyte C. Characterization of glucagon-like peptide-1 (GLP-1) agonist exposures reported to a single United States poison center. Clin Toxicol (Phila). 2025 Feb; 63(2):133-136. PMID: 39803696.
      View in: PubMed
    4. Segev O, Hoyte C, Taylor N, Katz A, Scolnik D, Zandberg E, Hassoun E, Glatstein M. Introduction of a New Toxicology Consult Service in a Large Tertiary Care Teaching Hospital. Isr Med Assoc J. 2024 Oct; 26(9):572-576. PMID: 39397503.
      View in: PubMed
    5. Simon MW, Olsen HA, Hoyte CO, Black JC, Reynolds KM, Dart RC, Monte AA. Clinical Effects of Psychedelic Substances Reported to United States Poison Centers: 2012 to 2022. Ann Emerg Med. 2024 Dec; 84(6):605-618. PMID: 39093248.
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    6. Matsler N, Pepin L, Banerji S, Hoyte C, Heard K. Use of large language models to optimize poison center charting. Clin Toxicol (Phila). 2024 Jun; 62(6):385-390. PMID: 38864738.
      View in: PubMed
    7. Nguyen HN, McElyea CWE, Chenoweth JA, Nowadly CD, Varney SM, Wilson BZ, Hoyte CO. Acute exposure to hydrazine reported to four United States regional poison centers: reconsidering a paradigm. Clin Toxicol (Phila). 2024 May; 62(5):322-328. PMID: 38813683.
      View in: PubMed
    8. Wilks MF, Hoyte C, Cumpston KL, Hassanian-Moghaddam H, Tse ML, Ferrer-Dufol A, Thiermann H. The Clinical Toxicology Recommendations Collaborative: purpose, organization, and methodology. Clin Toxicol (Phila). 2024 Feb; 62(2):76-81. PMID: 38465693.
      View in: PubMed
    9. Simon M, Kaplan S, Muschler K, Hoyte C, Brent J. The role of QRS complex prolongation in predicting severe toxicity in single-xenobiotic overdose. Clin Toxicol (Phila). 2024 Jan; 62(1):32-38. PMID: 38329803.
      View in: PubMed
    10. Segev O, Yochpaz S, Scolnik D, Zandberg E, Hoyte C, Rimon A, Glatstein M. Patients with Altered Mental Status May Benefit from Medical Toxicology Consultation. Isr Med Assoc J. 2024 Jan; 26(1):34-39. PMID: 38420640.
      View in: PubMed
    11. Mehrpour O, Saeedi F, Vohra V, Hoyte C. Outcome prediction of methadone poisoning in the United States: implications of machine learning in the National Poison Data System (NPDS). Drug Chem Toxicol. 2024 Sep; 47(5):556-563. PMID: 37941394.
      View in: PubMed
    12. Neumann NR, du Plessis A, van Hoving DJ, Hoyte CO, Lermer A, Wittels S, Marks C. Antivenom supply and demand: An analysis of antivenom availability and utilization in South Africa. Afr J Emerg Med. 2023 Dec; 13(4):245-249. PMID: 37745277.
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    13. Lavonas EJ, Akpunonu PD, Arens AM, Babu KM, Cao D, Hoffman RS, Hoyte CO, Mazer-Amirshahi ME, Stolbach A, St-Onge M, Thompson TM, Wang GS, Hoover AV, Drennan IR. 2023 American Heart Association Focused Update on the Management of Patients With Cardiac Arrest or Life-Threatening Toxicity Due to Poisoning: An Update to the American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation. 2023 10 17; 148(16):e149-e184. PMID: 37721023.
      View in: PubMed
    14. Pepin LC, Simon MW, Banerji S, Leonard J, Hoyte CO, Wang GS. Toxic Tetrahydrocannabinol (THC) Dose in Pediatric Cannabis Edible Ingestions. Pediatrics. 2023 09 01; 152(3). PMID: 37635689.
      View in: PubMed
    15. Cohen N, Mathew M, Brent J, Wax P, Davis AL, Obilom C, Burns MM, Canning J, Baumgartner K, Koons AL, Wiegand TJ, Judge B, Hoyte C, Chenoweth JA, Froberg B, Farrar H, Carey JL, Hendrickson RG, Hodgman M, Caravati EM, Christian MR, Wolk BJ, Seifert SA, Bentur Y, Levine M, Farrugia LA, Vearrier D, Minns AB, Kennedy JM, Kirschner RI, Aldy K, Schuh S, Campleman S, Li S, Myran DT, Feng L, Freedman SB, Finkelstein Y. Severe outcomes following pediatric cannabis intoxication: a prospective cohort study of an international toxicology surveillance registry. Clin Toxicol (Phila). 2023 08; 61(8):591-598. PMID: 37603042.
      View in: PubMed
    16. Mehrpour O, Hoyte C, Al Masud A, Biswas A, Schimmel J, Nakhaee S, Nasr MS, Delva-Clark H, Goss F. Deep learning neural network derivation and testing to distinguish acute poisonings. Expert Opin Drug Metab Toxicol. 2023 Jan-Jun; 19(6):367-380. PMID: 37395108.
      View in: PubMed
    17. Simon M, Hoyte C. A Case Report of Venezuelan Suntiger Tarantula (Psalmopoeus Irminia) Envenomation and Review of Tarantula Exposures. J Emerg Med. 2023 09; 65(3):e199-e203. PMID: 37635034.
      View in: PubMed
    18. Mehrpour O, Hoyte C, Nakhaee S, Megarbane B, Goss F. Using a decision tree algorithm to distinguish between repeated supra-therapeutic and acute acetaminophen exposures. BMC Med Inform Decis Mak. 2023 06 01; 23(1):102. PMID: 37264381.
      View in: PubMed
    19. Mehrpour O, Saeedi F, Nakhaee S, Tavakkoli Khomeini F, Hadianfar A, Amirabadizadeh A, Hoyte C. Comparison of decision tree with common machine learning models for prediction of biguanide and sulfonylurea poisoning in the United States: an analysis of the National Poison Data System. BMC Med Inform Decis Mak. 2023 04 06; 23(1):60. PMID: 37024869.
      View in: PubMed
    20. Mehrpour O, Hoyte C, Delva-Clark H, Al Masud A, Biswas A, Schimmel J, Nakhaee S, Goss F. Classification of acute poisoning exposures with machine learning models derived from the National Poison Data System. Basic Clin Pharmacol Toxicol. 2022 Dec; 131(6):566-574. PMID: 36181236.
      View in: PubMed
    21. Mehrpour O, Saeedi F, Hoyte C, Goss F, Shirazi FM. Correction: Utility of support vector machine and decision tree to identify the prognosis of metformin poisoning in the United States: analysis of National Poisoning Data System. BMC Pharmacol Toxicol. 2022 Sep 09; 23(1):68. PMID: 36085086.
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    22. Wang GS, Leonard J, Cornell A, Hoyte C. Adolescent US Poison Center Exposure Calls During the COVID-19 Pandemic. J Adolesc Health. 2022 12; 71(6):764-767. PMID: 36088226.
      View in: PubMed
    23. Mehrpour O, Saeedi F, Hoyte C, Goss F, Shirazi FM. Utility of support vector machine and decision tree to identify the prognosis of metformin poisoning in the United States: analysis of National Poisoning Data System. BMC Pharmacol Toxicol. 2022 07 13; 23(1):49. PMID: 35831909.
      View in: PubMed
    24. Mehrpour O, Hoyte C, Goss F, Shirazi FM, Nakhaee S. Decision tree algorithm can determine the outcome of repeated supratherapeutic ingestion (RSTI) exposure to acetaminophen: review of 4500 national poison data system cases. Drug Chem Toxicol. 2023 Nov; 46(4):692-698. PMID: 35670081.
      View in: PubMed
    25. Sudanagunta S, Camarena-Michel A, Pennington S, Leonard J, Hoyte C, Wang GS. Comparison of Two-Bag Versus Three-Bag N-Acetylcysteine Regimens for Pediatric Acetaminophen Toxicity. Ann Pharmacother. 2023 01; 57(1):36-43. PMID: 35587124.
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    26. Cohen N, Mathew M, Davis A, Brent J, Wax P, Schuh S, Freedman SB, Froberg B, Schwarz E, Canning J, Tortora L, Hoyte C, Koons AL, Burns MM, McFalls J, Wiegand TJ, Hendrickson RG, Judge B, Quang LS, Hodgman M, Chenoweth JA, Algren DA, Carey J, Caravati EM, Akpunonu P, Geib AJ, Seifert SA, Kazzi Z, Othong R, Greene SC, Holstege C, Tweet MS, Vearrier D, Pizon AF, Campleman SL, Li S, Aldy K, Finkelstein Y. Predictors of severe outcome following opioid intoxication in children. Clin Toxicol (Phila). 2022 06; 60(6):702-707. PMID: 35333145.
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    27. Mehrpour O, Saeedi F, Hoyte C, Hadianfar A, Nakhaee S, Brent J. Distinguishing characteristics of exposure to biguanide and sulfonylurea anti-diabetic medications in the United States. Am J Emerg Med. 2022 06; 56:171-177. PMID: 35398707.
      View in: PubMed
    28. Spyres MB, Padilla GK, Gerkin RD, Hoyte CO, Wolk BJ, Ruha AM. Late hemotoxicity following North American rattlesnake envenomation treated with crotalidae immune F(ab')2 (equine) antivenom and crotalidae immune polyvalent Fab (ovine) antivenom reported to the North American Snakebite Sub-registry. Clin Toxicol (Phila). 2022 07; 60(7):838-842. PMID: 35261320.
      View in: PubMed
    29. Mehrpour O, Saeedi F, Hadianfar A, M?garbane B, Hoyte C. Prognostic factors of acetaminophen exposure in the United States: An analysis of 39,000 patients. Hum Exp Toxicol. 2021 Dec; 40(12_suppl):S814-S825. PMID: 34772307.
      View in: PubMed
    30. Mehrpour O, Saeedi F, Hoyte C. Decision tree outcome prediction of acute acetaminophen exposure in the United States: A study of 30,000 cases from the National Poison Data System. Basic Clin Pharmacol Toxicol. 2022 Jan; 130(1):191-199. PMID: 34649297.
      View in: PubMed
    31. Hoyte C, Schimmel J, Hadianfar A, Banerji S, Nakhaee S, Mehrpour O. Toxic alcohol poisoning characteristics and treatments from 2000 to 2017 at a United States regional poison center. Daru. 2021 Dec; 29(2):367-376. PMID: 34709587.
      View in: PubMed
    32. Glatstein M, Lerman L, Gatt D, Scolnik D, Rimon A, Hoyte C, Iazar I. Echis coloratus envenomation in children: a retrospective case series. Clin Toxicol (Phila). 2022 Mar; 60(3):293-297. PMID: 34319210.
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    33. Amirabadizadeh A, Nakhaee S, Jahani F, Soorgi S, Hoyte CO, Mehrpour O. Prognostic indicators in critically ill poisoned patients: development of a risk-prediction nomogram. Drug Metab Pers Ther. 2020 09 29; 35(4). PMID: 34704692.
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    34. Amirabadizadeh A, Nakhaee S, Jahani F, Soorgi S, Hoyte CO, Mehrpour O. Prognostic indicators in critically ill poisoned patients: development of a risk-prediction nomogram. Drug Metab Pers Ther. 2020 Sep 28. PMID: 32986611.
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    35. Mehrpour O, Hoyte C, Amirabadizadeh A, Brent J. Clinical characteristics and time trends of hospitalized methadone exposures in the United States based on the Toxicology Investigators Consortium (ToxIC) case registry: 2010-2017. BMC Pharmacol Toxicol. 2020 07 22; 21(1):53. PMID: 32698849.
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    36. Nakhaee S, Brent J, Hoyte C, Farrokhfall K, Shirazi FM, Askari M, Mehrpour O. The effect of tramadol on blood glucose concentrations: a systematic review. Expert Rev Clin Pharmacol. 2020 May; 13(5):531-543. PMID: 32295441.
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    37. Glatstein M, Katz A, Taylor N, Werthein J, Zandberg E, Hoyte C. Publication outcomes of abstracts presented at 2013 North American Congress of Clinical Toxicology (NACCT) conference. Clin Toxicol (Phila). 2020 Feb 18; 1-4. PMID: 32067493.
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    38. Farkhondeh T, Khan H, Aschner M, Samini F, Pourbagher-Shahri AM, Aramjoo H, Roshanravan B, Hoyte C, Mehrpour O, Samarghandian S. Impact of Cannabis-Based Medicine on Alzheimer's Disease by Focusing on the Amyloid ?-Modifications: A Systematic Study. CNS Neurol Disord Drug Targets. 2020; 19(5):334-343. PMID: 32640965.
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    39. Bridwell RE, Baker KA, Hoyte CO, Ng PC. Digoxin Toxicity in a Patient with Pacemaker: A Case Report. Cureus. 2019 Nov 02; 11(11):e6056. PMID: 31819839.
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    40. Glatstein M, Lerman L, Friedman S, Carbell G, Munchak I, Valla U, Scolnik D, Hoyte C. Severe disseminated intravascular coagulation in a child envenomated by Echis coloratus and successful treatment with monovalent equine immunoglobulin G antivenom. Toxicon. 2019 Sep; 167:82-86. PMID: 31150660.
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    41. Glatstein M, Bonifacio Rino P, de Pinho S, Scolnik D, Pivko-Levi D, Hoyte C. Levocarnitine for the Treatment of Valproic Acid-Induced Hyperammonemic Encephalopathy in Children: The Experience of a Large, Tertiary Care Pediatric Hospital and a Poison Center. Am J Ther. 2019 May/Jun; 26(3):e344-e349. PMID: 29232283.
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    42. Glatstein M, Carbell G, Koplowitz J, Hoyte C. Publication outcomes of abstracts presented at an international toxicology conference. Clin Toxicol (Phila). 2020 01; 58(1):56-58. PMID: 30957630.
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    43. Wang GS, Hoyte C. Novel Drugs of Abuse. Pediatr Rev. 2019 Feb; 40(2):71-78. PMID: 30709973.
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    44. Hoyte C, Dart RC. Transition to two-bag intravenous acetylcysteine for acetaminophen overdose: a poison center's experience. Clin Toxicol (Phila). 2019 03; 57(3):217-218. PMID: 30689437.
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    45. Heard K, Monte AA, Hoyte CO. Brief Commentary: Consequences of Marijuana-Observations From the Emergency Department. Ann Intern Med. 2019 01 15; 170(2):124. PMID: 30615784.
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    46. Schimmel J, Camarena-Michel A, Hoyte C. Pediatric Cases Involving Chemical Burns to Garlic Used to Treat Warts. Dermatitis. 2019 Jan/Feb; 30(1):80-82. PMID: 30570580.
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    47. Glatstein M, Adir D, Galil B, Scolnik D, Rimon A, Pivko-Levy D, Hoyte C. Pediatric jellyfish envenomation in the Mediterranean Sea. Eur J Emerg Med. 2018 Dec; 25(6):434-439. PMID: 28639958.
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    48. Wang GS, Hoyte C, Roosevelt G, Heard K. The Continued Impact of Marijuana Legalization on Unintentional Pediatric Exposures in Colorado. Clin Pediatr (Phila). 2019 01; 58(1):114-116. PMID: 30288992.
      View in: PubMed
    49. Wang GS, Hoyte C. Review of Biguanide (Metformin) Toxicity. J Intensive Care Med. 2019 Nov-Dec; 34(11-12):863-876. PMID: 30126348.
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    50. Wang GS, Hoyte C. Common Substances of Abuse. Pediatr Rev. 2018 Aug; 39(8):403-414. PMID: 30068741.
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    51. Glatstein M, Carbell G, Scolnik D, Rimon A, Banerji S, Hoyte C. Pyridoxine for the treatment of isoniazid-induced seizures in intentional ingestions: The experience of a national poison center. Am J Emerg Med. 2018 10; 36(10):1775-1778. PMID: 29397257.
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    52. Brandehoff NP, Baker KA, Bonney CF, Ng PC, Schimmel J, Hoyte CO. Articles You May Have Missed. J Med Toxicol. 2018 06; 14(2):156-159. PMID: 29368219.
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    53. Glatstein M, Carbell G, Scolnik D, Rimon A, Hoyte C. Treatment of pediatric black widow spider envenomation: A national poison center's experience. Am J Emerg Med. 2018 06; 36(6):998-1002. PMID: 29133072.
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    54. Heard K, Marlin MB, Nappe T, Hoyte CO. Common marijuana-related cases encountered in the emergency department. Am J Health Syst Pharm. 2017 Nov 15; 74(22):1904-1908. PMID: 28947626.
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    55. Nappe TM, Hoyte CO. Pediatric Death Due to Myocarditis After Exposure to Cannabis. Clin Pract Cases Emerg Med. 2017 Aug; 1(3):166-170. PMID: 29849306.
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    56. Pivko-Levy D, Munchnak I, Rimon A, Balla U, Scolnik D, Hoyte C, Voliovitch Y, Glatstein M. Evaluation of antivenom therapy for Vipera palaestinae bites in children: experience of two large, tertiary care pediatric hospitals. Clin Toxicol (Phila). 2017 Apr; 55(4):235-240. PMID: 28103732.
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    57. Cao D, Srisuma S, Bronstein AC, Hoyte CO. Characterization of edible marijuana product exposures reported to United States poison centers. Clin Toxicol (Phila). 2016 Nov; 54(9):840-846. PMID: 27418198.
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    58. Lavonas EJ, Drennan IR, Gabrielli A, Heffner AC, Hoyte CO, Orkin AM, Sawyer KN, Donnino MW. Part 10: Special Circumstances of Resuscitation: 2015 American Heart Association Guidelines Update for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation. 2015 Nov 03; 132(18 Suppl 2):S501-18. PMID: 26472998.
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    59. Hoyte C, Terhune E, Carry P, McCanta A, Coel R. Borderline and Long QT Syndrome in Adolescent Athletes Taking Medications. J Adolesc Health. 2015 Aug; 57(2):218-21. PMID: 26206443.
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    60. Srisuma S, Hoyte CO, Wongvisavakorn S, Wanaukul W. Serotonin syndrome precipitated by sertraline and discontinuation of clozapine. Clin Toxicol (Phila). 2015; 53(8):840-1. PMID: 26161840.
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    61. Srisuma S, Bronstein AC, Hoyte CO. NBOMe and 2C substitute phenylethylamine exposures reported to the National Poison Data System. Clin Toxicol (Phila). 2015; 53(7):624-8. PMID: 26065360.
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    62. Chua-Tuan JL, Cao D, Iwanicki JL, Hoyte CO. Cardiac sodium channel blockade after an intentional ingestion of lacosamide, cyclobenzaprine, and levetiracetam: Case report. Clin Toxicol (Phila). 2015 Jul; 53(6):565-8. PMID: 25951877.
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    63. Monte AA, Bronstein AC, Cao DJ, Heard KJ, Hoppe JA, Hoyte CO, Iwanicki JL, Lavonas EJ. An outbreak of exposure to a novel synthetic cannabinoid. N Engl J Med. 2014 Jan 23; 370(4):389-90. PMID: 24450915.
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    64. Hoyte C. The toxicity of energy drinks: myth or reality? Clin Toxicol (Phila). 2013 Sep-Oct; 51(8):729-30. PMID: 23964852.
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    65. Hoyte CO, Albert D, Heard KJ. The use of energy drinks, dietary supplements, and prescription medications by United States college students to enhance athletic performance. J Community Health. 2013 Jun; 38(3):575-80. PMID: 23371823.
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    66. Hoyte CO, Leikin JB. Management of diethylene glycol ingestion. Clin Toxicol (Phila). 2012 Jul; 50(6):525-7. PMID: 22694101.
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    67. Hoyte CO, Cushing TA, Heard KJ. Anaphylaxis to black widow spider antivenom. Am J Emerg Med. 2012 Jun; 30(5):836.e1-2. PMID: 21641165.
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    68. Hoyte CO, Jacob J, Monte AA, Al-Jumaan M, Bronstein AC, Heard KJ. A characterization of synthetic cannabinoid exposures reported to the National Poison Data System in 2010. Ann Emerg Med. 2012 Oct; 60(4):435-8. PMID: 22575211.
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    69. de la Fuente FA, Hoyte C, Bryant SM. Push-ups may be hazardous to your health: an atraumatic etiology for bilateral shoulder dislocation. Am J Emerg Med. 2008 Jan; 26(1):116.e3-4. PMID: 18082811.
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