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Jose Ramon Castillo-Mancilla

TitleAssociate Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus

    Collapse Research 
    Collapse research activities and funding
    K23AI104315     (CASTILLO-MANCILLA, JOSE RAMON)Jun 20, 2013 - May 31, 2018
    Quantifying Drug Adherence and Drug Exposure to Antiretroviral Therapy
    Role: Principal Investigator

    R21AI124859     (CASTILLO-MANCILLA, JOSE RAMON)Mar 15, 2016 - Feb 28, 2018
    Impact of ART Adherence on HIV Persistence and Inflammation
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Anderson PL, Liu AY, Castillo-Mancilla JR, Gardner EM, Seifert SM, McHugh C, Wagner T, Campbell K, Morrow M, Ibrahim M, Buchbinder S, Bushman LR, Kiser JJ, MaWhinney S. Intracellular Tenofovir-Diphosphate and Emtricitabine-Triphosphate in Dried Blood Spots following Directly Observed Therapy: the DOT-DBS Study. Antimicrob Agents Chemother. 2017 Oct 16. PMID: 29038282.
      View in: PubMed
    2. MacBrayne CE, Castillo-Mancilla J, Burton JR, MaWhinney S, Wagner CB, Micke K, Fey J, Huntley RT, Larson B, Bushman LR, Kiser JJ. Small increase in dolutegravir trough, but equivalent total dolutegravir exposure with simeprevir in HIV/HCV seronegative volunteers. J Antimicrob Chemother. 2017 Oct 04. PMID: 29029135.
      View in: PubMed
    3. Erlandson KM, Kitch D, Wester WC, Kalayjian RC, Overton ET, Castillo-Mancilla J, Koletar SL, Benson CA, Campbell TB, Robertson K, Lok JJ. The Impact of Statin and ACE-inhibitor/Angiotensin Receptor Blocker Therapy on Cognitive Function in Adults with HIV Infection. Clin Infect Dis. 2017 Jul 27. PMID: 29020174.
      View in: PubMed
    4. Seifert SM, Castillo-Mancilla JR, Erlandson KM, Anderson PL. Inflammation and pharmacokinetics: potential implications for HIV-infection. Expert Opin Drug Metab Toxicol. 2017 Jun; 13(6):641-650. PMID: 28335648.
      View in: PubMed
    5. Chen X, Seifert SM, Castillo-Mancilla JR, Bushman LR, Zheng JH, Kiser JJ, MaWhinney S, Anderson PL. Model Linking Plasma and Intracellular Tenofovir/Emtricitabine with Deoxynucleoside Triphosphates. PLoS One. 2016; 11(11):e0165505. PMID: 27832147.
      View in: PubMed
    6. Castillo-Mancilla J, Seifert S, Campbell K, Coleman S, McAllister K, Zheng JH, Gardner EM, Liu A, Glidden DV, Grant R, Hosek S, Wilson CM, Bushman LR, MaWhinney S, Anderson PL. Emtricitabine-Triphosphate in Dried Blood Spots as a Marker of Recent Dosing. Antimicrob Agents Chemother. 2016 Nov; 60(11):6692-6697. PMID: 27572401.
      View in: PubMed
    7. Castillo-Mancilla JR, Brown TT, Erlandson KM, Palella FJ, Gardner EM, Macatangay BJ, Breen EC, Jacobson LP, Anderson PL, Wada NI. Suboptimal Adherence to Combination Antiretroviral Therapy Is Associated With Higher Levels of Inflammation Despite HIV Suppression. Clin Infect Dis. 2016 Dec 15; 63(12):1661-1667. PMID: 27660234.
      View in: PubMed
    8. Seifert SM, Chen X, Meditz AL, Castillo-Mancilla JR, Gardner EM, Predhomme JA, Clayton C, Austin G, Palmer BE, Zheng JH, Klein B, Kerr BJ, Guida LA, Rower C, Rower JE, Kiser JJ, Bushman LR, MaWhinney S, Anderson PL. Intracellular Tenofovir and Emtricitabine Anabolites in Genital, Rectal, and Blood Compartments from First Dose to Steady State. AIDS Res Hum Retroviruses. 2016 Oct/Nov; 32(10-11):981-991. PMID: 27526873.
      View in: PubMed
    9. Chen X, Castillo-Mancilla JR, Seifert SM, McAllister KB, Zheng JH, Bushman LR, MaWhinney S, Anderson PL. Analysis of the Endogenous Deoxynucleoside Triphosphate Pool in HIV-Positive and -Negative Individuals Receiving Tenofovir-Emtricitabine. Antimicrob Agents Chemother. 2016 Sep; 60(9):5387-92. PMID: 27353267; PMCID: PMC4997838 [Available on 03/01/17].
    10. Anderson PL, Reirden D, Castillo-Mancilla J. Pharmacologic Considerations for Preexposure Prophylaxis in Transgender Women. J Acquir Immune Defic Syndr. 2016 Aug 15; 72 Suppl 3:S230-4. PMID: 27429188; PMCID: PMC4955879.
    11. Castillo-Mancilla JR, Aquilante CL, Wempe MF, Smeaton LM, Firnhaber C, LaRosa AM, Kumarasamy N, Andrade A, Baheti G, Fletcher CV, Campbell TB, Haas DW, MaWhinney S, Anderson PL. Pharmacogenetics of unboosted atazanavir in HIV-infected individuals in resource-limited settings: a sub-study of the AIDS Clinical Trials Group (ACTG) PEARLS study (NWCS 342). J Antimicrob Chemother. 2016 06; 71(6):1609-18. PMID: 26892777; PMCID: PMC4867099 [Available on 06/01/17].
    12. Zheng JH, Rower C, McAllister K, Castillo-Mancilla J, Klein B, Meditz A, Guida LA, Kiser JJ, Bushman LR, Anderson PL. Application of an intracellular assay for determination of tenofovir-diphosphate and emtricitabine-triphosphate from erythrocytes using dried blood spots. J Pharm Biomed Anal. 2016 Apr 15; 122:16-20. PMID: 26829517; PMCID: PMC4764437 [Available on 04/15/17].
    13. Chai PR, Castillo-Mancilla J, Buffkin E, Darling C, Rosen RK, Horvath KJ, Boudreaux ED, Robbins GK, Hibberd PL, Boyer EW. Utilizing an Ingestible Biosensor to Assess Real-Time Medication Adherence. J Med Toxicol. 2015 Dec; 11(4):439-44. PMID: 26245878; PMCID: PMC4675608 [Available on 12/01/16].
    14. Castillo-Mancilla JR, Meditz A, Wilson C, Zheng JH, Palmer BE, Lee EJ, Gardner EM, Seifert S, Kerr B, Bushman LR, MaWhinney S, Anderson PL. Reduced immune activation during tenofovir-emtricitabine therapy in HIV-negative individuals. J Acquir Immune Defic Syndr. 2015 Apr 15; 68(5):495-501. PMID: 25763783; PMCID: PMC4358752.
    15. Heumann C, Cohn SE, Krishnan S, Castillo-Mancilla JR, Cespedes M, Floris-Moore M, Smith KY. Regional variation in HIV clinical trials participation in the United States. South Med J. 2015 Feb; 108(2):107-16. PMID: 25688896; PMCID: PMC4356522.
    16. Castillo-Mancilla JR, Searls K, Caraway P, Zheng JH, Gardner EM, Predhomme J, Bushman LR, Anderson PL, Meditz AL. Short communication: Tenofovir diphosphate in dried blood spots as an objective measure of adherence in HIV-infected women. AIDS Res Hum Retroviruses. 2015 Apr; 31(4):428-32. PMID: 25328112; PMCID: PMC4378663.
    17. Seifert SM, Glidden DV, Meditz AL, Castillo-Mancilla JR, Gardner EM, Predhomme JA, Rower C, Klein B, Kerr BJ, Guida LA, Zheng JH, Bushman LR, Anderson PL. Dose response for starting and stopping HIV preexposure prophylaxis for men who have sex with men. Clin Infect Dis. 2015 Mar 01; 60(5):804-10. PMID: 25409469; PMCID: PMC4402345.
    18. Castillo-Mancilla JR, Cohn SE, Krishnan S, Cespedes M, Floris-Moore M, Schulte G, Pavlov G, Mildvan D, Smith KY. Minorities remain underrepresented in HIV/AIDS research despite access to clinical trials. HIV Clin Trials. 2014 Jan-Feb; 15(1):14-26. PMID: 24518211; PMCID: PMC4031907.
    19. Zheng JH, Guida LA, Rower C, Castillo-Mancilla J, Meditz A, Klein B, Kerr BJ, Langness J, Bushman L, Kiser J, Anderson PL. Quantitation of tenofovir and emtricitabine in dried blood spots (DBS) with LC-MS/MS. J Pharm Biomed Anal. 2014 Jan; 88:144-51. PMID: 24055850; PMCID: PMC3842403.
    20. Carten ML, Castillo-Mancilla JR, Allshouse AA, Johnson SC. Characteristics of foreign-born HIV infected individuals and differences by region of origin and gender. J Immigr Minor Health. 2013 Aug; 15(4):667-72. PMID: 22562621.
      View in: PubMed
    21. Henao-Martínez AF, Castillo-Mancilla JR, Barron MA, Nichol AC. Combination Antifungal Therapy in the Treatment of Scedosporium apiospermum Central Nervous System Infections. Case Rep Infect Dis. 2013; 2013:589490. PMID: 23738164; PMCID: PMC3657419.
    22. Henao-Martínez AF, Castillo-Mancilla JR. The Hispanic HIV Epidemic. Curr Infect Dis Rep. 2013 Feb; 15(1):46-51. PMID: 23184612.
      View in: PubMed
    23. Henao-Martínez AF, González-Fontal GR, Castillo-Mancilla JR, Yang IV. Enterobacteriaceae bacteremias among cancer patients: an observational cohort study. Int J Infect Dis. 2013 Jun; 17(6):e374-8. PMID: 23313157; PMCID: PMC3632647.
    24. Castillo-Mancilla JR, Zheng JH, Rower JE, Meditz A, Gardner EM, Predhomme J, Fernandez C, Langness J, Kiser JJ, Bushman LR, Anderson PL. Tenofovir, emtricitabine, and tenofovir diphosphate in dried blood spots for determining recent and cumulative drug exposure. AIDS Res Hum Retroviruses. 2013 Feb; 29(2):384-90. PMID: 22935078; PMCID: PMC3552442.
    25. Kile DA, MaWhinney S, Aquilante CL, Rower JE, Castillo-Mancilla JR, Anderson PL. A population pharmacokinetic-pharmacogenetic analysis of atazanavir. AIDS Res Hum Retroviruses. 2012 Oct; 28(10):1227-34. PMID: 22394315.
      View in: PubMed
    26. Castillo-Mancilla JR, Campbell TB. Comparative effectiveness of efavirenz-based antiretroviral regimens in resource-limited settings. J Comp Eff Res. 2012 Mar; 1(2):157-170. PMID: 22707879.
      View in: PubMed
    27. Castillo-Mancilla J, Allshouse A, Collins C, Hastings-Tolsma M, Campbell TB, Mawhinney S. Differences in sexual risk behavior and HIV/AIDS risk factors among foreign-born and US-born Hispanic women. J Immigr Minor Health. 2012 Feb; 14(1):89-99. PMID: 21932002; PMCID: PMC4504232.
    28. Castillo-Mancilla JR, Carten M. The need for a US registry of HIV in foreign-born people. Lancet Infect Dis. 2010 Jun; 10(6):370-1. PMID: 20510276.
      View in: PubMed
    29. Christensen JB, Vitko NP, Voskuil MI, Castillo-Mancilla JR. Implantable cardiac defibrillator pocket infection due to a previously undescribed Cupriavidus species. J Clin Microbiol. 2010 Jul; 48(7):2623-5. PMID: 20427695; PMCID: PMC2897534.
    30. Castillo-Mancilla JR. The changing HIV epidemic in Mexico. JAMA. 2008 Dec 03; 300(21):2484. PMID: 19050189.
      View in: PubMed
    31. Panchal R, Avery R, Mehta AC, Castillo JR, Farver C, Aboussouan LS. A young man with a cough, an abnormal chest radiograph, and multiple skin lesions. Cleve Clin J Med. 2006 Mar; 73(3):273-80. PMID: 16548450.
      View in: PubMed
    32. Castillo JR, Kirchner E, Farver C, Calabrese LH. Cryoglobulinemic vasculitis and lymphocytic interstitial pneumonitis in a person with HIV infection. AIDS Read. 2005 May; 15(5):252-5. PMID: 15900636.
      View in: PubMed
    33. Castillo JR, Gordon SM, Arroliga AC. Cross-transmission in the intensive care unit: one piece of the puzzle. Crit Care Med. 2005 May; 33(5):1147-8. PMID: 15891354.
      View in: PubMed
    34. Castillo JR, Zagler A, Carrillo-Jimenez R, Hennekens CH. Brain natriuretic peptide: a potential marker for mortality in septic shock. Int J Infect Dis. 2004 Sep; 8(5):271-4. PMID: 15325595.
      View in: PubMed
    35. Volkow P, Jacquemin B, Vilar-Compte D, Castillo RJ. Contact with hospital syringes containing body fluids. Implications for medical waste management regulation. Salud Publica Mex. 2003 Mar-Apr; 45(2):120-2. PMID: 12736991.
      View in: PubMed
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