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David Andrew Ammar

TitleAssoc Professor-Clinical
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus

    Collapse Research 
    Collapse research activities and funding
    F32DK009984     (AMMAR, DAVID A)Sep 1, 1999
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Tewari-Singh N, Goswami DG, Kant R, Ammar DA, Kumar D, Enzenauer RW, Casillas RP, Croutch CR, Petrash JM, Agarwal R. Histopathological and Molecular Changes in the Rabbit Cornea From Arsenical Vesicant Lewisite Exposure. Toxicol Sci. 2017 Dec 01; 160(2):420-428. PMID: 28973427.
      View in: PubMed
    2. Laughter MR, Ammar DA, Bardill JR, Pena B, Kahook MY, Lee DJ, Park D. A Self-Assembling Injectable Biomimetic Microenvironment Encourages Retinal Ganglion Cell Axon Extension in Vitro. ACS Appl Mater Interfaces. 2016 Aug 17; 8(32):20540-8. PMID: 27434231.
      View in: PubMed
    3. Zhang X, Liu N, Mak PU, Pun SH, Vai MI, Masihzadeh O, Kahook MY, Lei TC, Ammar DA. Three-Dimensional Segmentation and Quantitative Measurement of the Aqueous Outflow System of Intact Mouse Eyes Based on Spectral Two-Photon Microscopy Techniques. Invest Ophthalmol Vis Sci. 2016 06 01; 57(7):3159-67. PMID: 27309620; PMCID: PMC4928697 [Available on 12/01/16].
    4. Chang KC, Li L, Sanborn TM, Shieh B, Lenhart P, Ammar D, LaBarbera DV, Petrash JM. Characterization of Emodin as a Therapeutic Agent for Diabetic Cataract. J Nat Prod. 2016 05 27; 79(5):1439-44. PMID: 27140653.
      View in: PubMed
    5. Tewari-Singh N, Croutch CR, Tuttle R, Goswami DG, Kant R, Peters E, Culley T, Ammar DA, Enzenauer RW, Petrash JM, Casillas RP, Agarwal R. Clinical progression of ocular injury following arsenical vesicant lewisite exposure. Cutan Ocul Toxicol. 2016 Dec; 35(4):319-28. PMID: 27002633.
      View in: PubMed
    6. Goswami DG, Tewari-Singh N, Dhar D, Kumar D, Agarwal C, Ammar DA, Kant R, Enzenauer RW, Petrash JM, Agarwal R. Nitrogen Mustard-Induced Corneal Injury Involves DNA Damage and Pathways Related to Inflammation, Epithelial-Stromal Separation, and Neovascularization. Cornea. 2016 Feb; 35(2):257-66. PMID: 26555588; PMCID: PMC4706783 [Available on 02/01/17].
    7. Mueller NH, Fogueri U, Pedler MG, Montana K, Petrash JM, Ammar DA. Impact of Subunit Composition on the Uptake of a-Crystallin by Lens and Retina. PLoS One. 2015; 10(9):e0137659. PMID: 26355842; PMCID: PMC4565700.
    8. SooHoo JR, Seibold LK, Ammar DA, Kahook MY. Ultrastructural Changes in Human Trabecular Meshwork Tissue after Laser Trabeculoplasty. J Ophthalmol. 2015; 2015:476138. PMID: 26064672; PMCID: PMC4443779.
    9. Masihzadeh O, Lei TC, Domingue SR, Kahook MY, Bartels RA, Ammar DA. Third harmonic generation microscopy of a mouse retina. Mol Vis. 2015; 21:538-47. PMID: 25999681; PMCID: PMC4440497.
    10. Nagaraj RH, Nahomi RB, Mueller NH, Raghavan CT, Ammar DA, Petrash JM. Therapeutic potential of a-crystallin. Biochim Biophys Acta. 2016 Jan; 1860(1 Pt B):252-7. PMID: 25840354; PMCID: PMC4591086 [Available on 01/01/17].
    11. Snow A, Shieh B, Chang KC, Pal A, Lenhart P, Ammar D, Ruzycki P, Palla S, Reddy GB, Petrash JM. Aldose reductase expression as a risk factor for cataract. Chem Biol Interact. 2015 Jun 05; 234:247-53. PMID: 25541468; PMCID: PMC4414723.
    12. Christopher KL, Pedler MG, Shieh B, Ammar DA, Petrash JM, Mueller NH. Alpha-crystallin-mediated protection of lens cells against heat and oxidative stress-induced cell death. Biochim Biophys Acta. 2014 Feb; 1843(2):309-15. PMID: 24275510; PMCID: PMC3901642.
    13. Lei TC, Masihzadeh O, Kahook MY, Ammar DA. Imaging the effects of prostaglandin analogues on cultured trabecular meshwork cells by coherent anti-stokes Raman scattering. Invest Ophthalmol Vis Sci. 2013 Sep 03; 54(9):5972-80. PMID: 23900606; PMCID: PMC3762330.
    14. Ammar DA, Lei TC, Kahook MY, Masihzadeh O. Imaging the intact mouse cornea using coherent anti-stokes Raman scattering (CARS). Invest Ophthalmol Vis Sci. 2013 Aug 05; 54(8):5258-65. PMID: 23821187; PMCID: PMC3736760.
    15. Famili A, Ammar DA, Kahook MY. Ethyl pyruvate treatment mitigates oxidative stress damage in cultured trabecular meshwork cells. Mol Vis. 2013; 19:1304-9. PMID: 23805037; PMCID: PMC3692399.
    16. Block E, Greco M, Vitek D, Masihzadeh O, Ammar DA, Kahook MY, Mandava N, Durfee C, Squier J. Simultaneous spatial and temporal focusing for tissue ablation. Biomed Opt Express. 2013 Jun 01; 4(6):831-41. PMID: 23761847; PMCID: PMC3675863.
    17. Masihzadeh O, Ammar DA, Kahook MY, Lei TC. Coherent anti-stokes Raman scattering (CARS) microscopy: a novel technique for imaging the retina. Invest Ophthalmol Vis Sci. 2013 May 01; 54(5):3094-101. PMID: 23580484; PMCID: PMC3643396.
    18. Ammar DA, Mandava N, Kahook MY. The effects of aflibercept on the viability and metabolism of ocular cells in vitro. Retina. 2013 May; 33(5):1056-61. PMID: 23266881.
      View in: PubMed
    19. Masihzadeh O, Ammar DA, Kahook MY, Gibson EA, Lei TC. Direct trabecular meshwork imaging in porcine eyes through multiphoton gonioscopy. J Biomed Opt. 2013 Mar; 18(3):036009. PMID: 23515864.
      View in: PubMed
    20. Ammar DA, Kahook MY. In vitro effects of verteporfin on ocular cells. Mol Vis. 2013; 19:424-9. PMID: 23441114; PMCID: PMC3580985.
    21. Mueller NH, Ammar DA, Petrash JM. Cell penetration peptides for enhanced entry of aB-crystallin into lens cells. Invest Ophthalmol Vis Sci. 2013 Jan 02; 54(1):2-8. PMID: 23150610; PMCID: PMC3541946.
    22. Seibold LK, Soohoo JR, Ammar DA, Kahook MY. Preclinical investigation of ab interno trabeculectomy using a novel dual-blade device. Am J Ophthalmol. 2013 Mar; 155(3):524-529.e2. PMID: 23218696.
      View in: PubMed
    23. Seibold LK, Ammar DA, Kahook MY. Acute effects of glaucoma medications and benzalkonium chloride on pre-adipocyte proliferation and adipocyte cytotoxicity in vitro. Curr Eye Res. 2013 Jan; 38(1):70-4. PMID: 23078159.
      View in: PubMed
    24. Tewari-Singh N, Jain AK, Inturi S, Ammar DA, Agarwal C, Tyagi P, Kompella UB, Enzenauer RW, Petrash JM, Agarwal R. Silibinin, dexamethasone, and doxycycline as potential therapeutic agents for treating vesicant-inflicted ocular injuries. Toxicol Appl Pharmacol. 2012 Oct 01; 264(1):23-31. PMID: 22841772; PMCID: PMC3928638.
    25. Masihzadeh O, Lei TC, Ammar DA, Kahook MY, Gibson EA. A multiphoton microscope platform for imaging the mouse eye. Mol Vis. 2012; 18:1840-8. PMID: 22815637; PMCID: PMC3398498.
    26. Ammar DA, Hamweyah KM, Kahook MY. Antioxidants Protect Trabecular Meshwork Cells From Hydrogen Peroxide-Induced Cell Death. Transl Vis Sci Technol. 2012; 1(1):4. PMID: 24049700.
      View in: PubMed
    27. Kahook MY, Fechtner RD, Katz LJ, Noecker RJ, Ammar DA. A comparison of active ingredients and preservatives between brand name and generic topical glaucoma medications using liquid chromatography-tandem mass spectrometry. Curr Eye Res. 2012 Feb; 37(2):101-8. PMID: 22040280.
      View in: PubMed
    28. Lei TC, Ammar DA, Masihzadeh O, Gibson EA, Kahook MY. Label-free imaging of trabecular meshwork cells using Coherent Anti-Stokes Raman Scattering (CARS) microscopy. Mol Vis. 2011; 17:2628-33. PMID: 22025898; PMCID: PMC3198498.
    29. Ammar DA, Kahook MY. Effects of benzalkonium chloride- or polyquad-preserved fixed combination glaucoma medications on human trabecular meshwork cells. Mol Vis. 2011; 17:1806-13. PMID: 21750606; PMCID: PMC3133848.
    30. Johnson AW, Ammar DA, Kahook MY. Two-photon imaging of the mouse eye. Invest Ophthalmol Vis Sci. 2011 Jun 09; 52(7):4098-105. PMID: 21447675; PMCID: PMC3175967.
    31. Ammar DA, Kahook MY. Effects of glaucoma medications and preservatives on cultured human trabecular meshwork and non-pigmented ciliary epithelial cell lines. Br J Ophthalmol. 2011 Oct; 95(10):1466-9. PMID: 21602479.
      View in: PubMed
    32. Ammar DA, Noecker RJ, Kahook MY. Effects of benzalkonium chloride- and polyquad-preserved combination glaucoma medications on cultured human ocular surface cells. Adv Ther. 2011 Jun; 28(6):501-10. PMID: 21603985.
      View in: PubMed
    33. Masihzadeh O, Ammar DA, Lei TC, Gibson EA, Kahook MY. Real-time measurements of nicotinamide adenine dinucleotide in live human trabecular meshwork cells: effects of acute oxidative stress. Exp Eye Res. 2011 Sep; 93(3):316-20. PMID: 21354135.
      View in: PubMed
    34. Ammar DA, Lei TC, Masihzadeh O, Gibson EA, Kahook MY. Trans-scleral imaging of the human trabecular meshwork by two-photon microscopy. Mol Vis. 2011 Feb 24; 17:583-90. PMID: 21386924; PMCID: PMC3049734.
    35. Liu L, Ammar DA, Ross LA, Mandava N, Kahook MY, Carpenter JF. Silicone oil microdroplets and protein aggregates in repackaged bevacizumab and ranibizumab: effects of long-term storage and product mishandling. Invest Ophthalmol Vis Sci. 2011 Feb; 52(2):1023-34. PMID: 21051703; PMCID: PMC3053093.
    36. Gibson EA, Masihzadeh O, Lei TC, Ammar DA, Kahook MY. Multiphoton microscopy for ophthalmic imaging. J Ophthalmol. 2011; 2011:870879. PMID: 21274261; PMCID: PMC3022205.
    37. Ammar DA, Noecker RJ, Kahook MY. Effects of benzalkonium chloride-preserved, polyquad-preserved, and sofZia-preserved topical glaucoma medications on human ocular epithelial cells. Adv Ther. 2010 Nov; 27(11):837-45. PMID: 20931366.
      View in: PubMed
    38. Kahook MY, Ammar DA. In vitro effects of antivascular endothelial growth factors on cultured human trabecular meshwork cells. J Glaucoma. 2010 Sep; 19(7):437-41. PMID: 20164801.
      View in: PubMed
    39. Kahook MY, Ammar DA. In vitro toxicity of topical ocular prostaglandin analogs and preservatives on corneal epithelial cells. J Ocul Pharmacol Ther. 2010 Jun; 26(3):259-63. PMID: 20565312.
      View in: PubMed
    40. Kahook MY, Liu L, Ruzycki P, Mandava N, Carpenter JF, Petrash JM, Ammar DA. High-molecular-weight aggregates in repackaged bevacizumab. Retina. 2010 Jun; 30(6):887-92. PMID: 20458261.
      View in: PubMed
    41. Ammar DA, Lei TC, Gibson EA, Kahook MY. Two-photon imaging of the trabecular meshwork. Mol Vis. 2010 May 29; 16:935-44. PMID: 20596237; PMCID: PMC2890557.
    42. Ammar DA, Kahook MY. The effects of combination glaucoma medications on ocular surface epithelial cells. Adv Ther. 2009 Oct; 26(10):970-5. PMID: 19921496.
      View in: PubMed
    43. Kahook MY, Kimura AE, Wong LJ, Ammar DA, Maycotte MA, Mandava N. Sustained elevation in intraocular pressure associated with intravitreal bevacizumab injections. Ophthalmic Surg Lasers Imaging. 2009 May-Jun; 40(3):293-5. PMID: 19485295.
      View in: PubMed
    44. Lu M, Ammar D, Ives H, Albrecht F, Gluck SL. Physical interaction between aldolase and vacuolar H+-ATPase is essential for the assembly and activity of the proton pump. J Biol Chem. 2007 Aug 24; 282(34):24495-503. PMID: 17576770.
      View in: PubMed
    45. Ammar DA, Zhou R, Forte JG, Yao X. Syntaxin 3 is required for cAMP-induced acid secretion: streptolysin O-permeabilized gastric gland model. Am J Physiol Gastrointest Liver Physiol. 2002 Jan; 282(1):G23-33. PMID: 11751154.
      View in: PubMed
    46. Ammar DA, Nguyen PN, Forte JG. Functionally distinct pools of actin in secretory cells. Am J Physiol Cell Physiol. 2001 Aug; 281(2):C407-17. PMID: 11443040.
      View in: PubMed
    47. Ammar DA, Thompson DA. Human type 2 neuropeptide Y receptor gene. Isolation and characterization. Methods Mol Biol. 2000; 153:25-43. PMID: 10957982.
      View in: PubMed
    48. Ammar DA, Hughes BA, Thompson DA. Neuropeptide Y and the retinal pigment epithelium: receptor subtypes, signaling, and bioelectrical responses. Invest Ophthalmol Vis Sci. 1998 Sep; 39(10):1870-8. PMID: 9727410.
      View in: PubMed
    49. Jacquin-Joly E, Burnet M, Fran├žois MC, Ammar D, Meillour PN, Descoins C. cDNA cloning and sequence determination of the pheromone biosynthesis activating neuropeptide of Mamestra brassicae: a new member of the PBAN family. Insect Biochem Mol Biol. 1998 Apr; 28(4):251-8. PMID: 9684333.
      View in: PubMed
    50. Ammar DA, Eadie DM, Wong DJ, Ma YY, Kolakowski LF, Yang-Feng TL, Thompson DA. Characterization of the human type 2 neuropeptide Y receptor gene (NPY2R) and localization to the chromosome 4q region containing the type 1 neuropeptide Y receptor gene. Genomics. 1996 Dec 15; 38(3):392-8. PMID: 8975716.
      View in: PubMed
    51. Tal M, Ammar DA, Karpuj M, Krizhanovsky V, Naim M, Thompson DA. A novel putative neuropeptide receptor expressed in neural tissue, including sensory epithelia. Biochem Biophys Res Commun. 1995 Apr 17; 209(2):752-9. PMID: 7733947.
      View in: PubMed
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