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Niklaus H Mueller

TitleAsst Professor-Research
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-Ophthalmology
Phone303/724-3013

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Como CN, Bubak AN, Blackmon AM, Jones D, Mueller NH, Davidson R, Nagel MA. Varicella Zoster Virus Induces Differential Cell-Type Specific Responses in Human Corneal Epithelial Cells and Keratocytes. Invest Ophthalmol Vis Sci. 2019 Feb 01; 60(2):704-711. PMID: 30786281.
      View in: PubMed
    2. Droho S, Keener ME, Mueller NH. Changes in function but not oligomeric size are associated with aB-crystallin lysine substitution. Biochem Biophys Rep. 2018 Jul; 14:1-6. PMID: 29872727.
      View in: PubMed
    3. Droho S, Keener ME, Mueller NH. Heparan sulfate mediates cell uptake of aB-crystallin fused to the glycoprotein C cell penetration peptide. Biochim Biophys Acta Mol Cell Res. 2018 Apr; 1865(4):598-604. PMID: 29408057.
      View in: PubMed
    4. Mueller NH, Fogueri U, Pedler MG, Montana K, Petrash JM, Ammar DA. Impact of Subunit Composition on the Uptake of a-Crystallin by Lens and Retina. PLoS One. 2015; 10(9):e0137659. PMID: 26355842; PMCID: PMC4565700.
      View in: PubMed, PubMed Central
    5. Nagaraj RH, Nahomi RB, Mueller NH, Raghavan CT, Ammar DA, Petrash JM. Therapeutic potential of a-crystallin. Biochim Biophys Acta. 2016 Jan; 1860(1 Pt B):252-7. PMID: 25840354; PMCID: PMC4591086 [Available on 01/01/17].
      View in: PubMed, PubMed Central
    6. Christopher KL, Pedler MG, Shieh B, Ammar DA, Petrash JM, Mueller NH. Alpha-crystallin-mediated protection of lens cells against heat and oxidative stress-induced cell death. Biochim Biophys Acta. 2014 Feb; 1843(2):309-15. PMID: 24275510; PMCID: PMC3901642.
      View in: PubMed, PubMed Central
    7. Mueller NH, Gilden D, Cohrs RJ. Varicella-zoster virus open reading frame 48 encodes an active nuclease. J Virol. 2013 Nov; 87(21):11936-8. PMID: 23966396; PMCID: PMC3807315.
      View in: PubMed, PubMed Central
    8. Mueller NH, Ammar DA, Petrash JM. Cell penetration peptides for enhanced entry of aB-crystallin into lens cells. Invest Ophthalmol Vis Sci. 2013 Jan 02; 54(1):2-8. PMID: 23150610; PMCID: PMC3541946.
      View in: PubMed, PubMed Central
    9. Mueller NH, Bos NL, Seitz S, Wellish M, Mahalingam R, Gilden D, Cohrs RJ. Recombinant monoclonal antibody recognizes a unique epitope on varicella-zoster virus immediate-early 63 protein. J Virol. 2012 Jun; 86(11):6345-9. PMID: 22438547; PMCID: PMC3372203.
      View in: PubMed, PubMed Central
    10. Ezgimen M, Lai H, Mueller NH, Lee K, Cuny G, Ostrov DA, Padmanabhan R. Characterization of the 8-hydroxyquinoline scaffold for inhibitors of West Nile virus serine protease. Antiviral Res. 2012 Apr; 94(1):18-24. PMID: 22343093; PMCID: PMC3331929.
      View in: PubMed, PubMed Central
    11. Validandi V, Reddy VS, Srinivas PN, Mueller NH, Bhagyalaxmi SG, Padma T, Petrash JM, Reddy GB. Temperature-dependent structural and functional properties of a mutant (F71L) aA-crystallin: molecular basis for early onset of age-related cataract. FEBS Lett. 2011 Dec 15; 585(24):3884-9. PMID: 22085609; PMCID: PMC4103624.
      View in: PubMed, PubMed Central
    12. Brazeau E, Wellish M, Kaufer BB, Tischer BK, Gray W, Zhou F, Osterrieder N, Hanlon T, Golive A, Hall T, Nair S, Owens GP, Mueller NH, Cohrs RJ, Pugazhenthi S, Gilden D, Mahalingam R. Simian varicella virus open reading frame 63/70 expression is required for efficient virus replication in culture. J Neurovirol. 2011 Jun; 17(3):274-80. PMID: 21479719; PMCID: PMC3204661.
      View in: PubMed, PubMed Central
    13. Mueller NH, Walters MS, Marcus RA, Graf LL, Prenni J, Gilden D, Silverstein SJ, Cohrs RJ. Identification of phosphorylated residues on varicella-zoster virus immediate-early protein ORF63. J Gen Virol. 2010 May; 91(Pt 5):1133-7. PMID: 20089801; PMCID: PMC2888152.
      View in: PubMed, PubMed Central
    14. Mueller NH, Graf LL, Orlicky D, Gilden D, Cohrs RJ. Phosphorylation of the nuclear form of varicella-zoster virus immediate-early protein 63 by casein kinase II at serine 186. J Virol. 2009 Dec; 83(23):12094-100. PMID: 19759161; PMCID: PMC2786752.
      View in: PubMed, PubMed Central
    15. Ezgimen MD, Mueller NH, Teramoto T, Padmanabhan R. Effects of detergents on the West Nile virus protease activity. Bioorg Med Chem. 2009 May 01; 17(9):3278-82. PMID: 19369080; PMCID: PMC2817951.
      View in: PubMed, PubMed Central
    16. Tomlinson SM, Malmstrom RD, Russo A, Mueller N, Pang YP, Watowich SJ. Structure-based discovery of dengue virus protease inhibitors. Antiviral Res. 2009 Jun; 82(3):110-4. PMID: 19428601; PMCID: PMC2680748.
      View in: PubMed, PubMed Central
    17. Gilden D, Nagel MA, Mahalingam R, Mueller NH, Brazeau EA, Pugazhenthi S, Cohrs RJ. Clinical and molecular aspects of varicella zoster virus infection. Future Neurol. 2009 Jan 01; 4(1):103-117. PMID: 19946620.
      View in: PubMed
    18. Mueller NH, Gilden DH, Cohrs RJ, Mahalingam R, Nagel MA. Varicella zoster virus infection: clinical features, molecular pathogenesis of disease, and latency. Neurol Clin. 2008 Aug; 26(3):675-97, viii. PMID: 18657721; PMCID: PMC2754837.
      View in: PubMed, PubMed Central
    19. Mueller NH, Pattabiraman N, Ansarah-Sobrinho C, Viswanathan P, Pierson TC, Padmanabhan R. Identification and biochemical characterization of small-molecule inhibitors of west nile virus serine protease by a high-throughput screen. Antimicrob Agents Chemother. 2008 Sep; 52(9):3385-93. PMID: 18606844; PMCID: PMC2533463.
      View in: PubMed, PubMed Central
    20. Mueller NH, Graf LL, Shearer AJ, Owens GP, Gilden DH, Cohrs RJ. Construction of recombinant mouse IgG1 antibody directed against varicella zoster virus immediate early protein 63. Hybridoma (Larchmt). 2008 Feb; 27(1):1-10. PMID: 18294070; PMCID: PMC2938744.
      View in: PubMed, PubMed Central
    21. Mueller NH, Yon C, Ganesh VK, Padmanabhan R. Characterization of the West Nile virus protease substrate specificity and inhibitors. Int J Biochem Cell Biol. 2007; 39(3):606-14. PMID: 17188926.
      View in: PubMed
    22. Padmanabhan R, Mueller N, Reichert E, Yon C, Teramoto T, Kono Y, Takhampunya R, Ubol S, Pattabiraman N, Falgout B, Ganesh VK, Murthy K. Multiple enzyme activities of flavivirus proteins. Novartis Found Symp. 2006; 277:74-84; discussion 84-6, 251-3. PMID: 17319155.
      View in: PubMed
    23. Yon C, Teramoto T, Mueller N, Phelan J, Ganesh VK, Murthy KH, Padmanabhan R. Modulation of the nucleoside triphosphatase/RNA helicase and 5'-RNA triphosphatase activities of Dengue virus type 2 nonstructural protein 3 (NS3) by interaction with NS5, the RNA-dependent RNA polymerase. J Biol Chem. 2005 Jul 22; 280(29):27412-9. PMID: 15917225.
      View in: PubMed
    24. Ganesh VK, Muller N, Judge K, Luan CH, Padmanabhan R, Murthy KH. Identification and characterization of nonsubstrate based inhibitors of the essential dengue and West Nile virus proteases. Bioorg Med Chem. 2005 Jan 03; 13(1):257-64. PMID: 15582469.
      View in: PubMed
    25. Hicks A, Potula R, Sui YJ, Villinger F, Pinson D, Adany I, Li Z, Long C, Cheney P, Marcario J, Novembre F, Mueller N, Kumar A, Major E, Narayan O, Buch S. Neuropathogenesis of lentiviral infection in macaques: roles of CXCR4 and CCR5 viruses and interleukin-4 in enhancing monocyte chemoattractant protein-1 production in macrophages. Am J Pathol. 2002 Sep; 161(3):813-22. PMID: 12213709; PMCID: PMC1867257.
      View in: PubMed, PubMed Central
    26. Ehsani ME, Abraha TW, Netherland-Snell C, Mueller N, Taylor MM, Holwerda B. Generation of mutant murine cytomegalovirus strains from overlapping cosmid and plasmid clones. J Virol. 2000 Oct; 74(19):8972-9. PMID: 10982341; PMCID: PMC102093.
      View in: PubMed, PubMed Central
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