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Brian S DeDecker

TitleSenior Instructor
InstitutionUniversity of Colorado Boulder
DepartmentBiology-MCD Instruction

    Collapse Research 
    Collapse research activities and funding
    R03NS075458     (DEDECKER, BRIAN SCOTT)May 1, 2011 - Apr 30, 2013
    NIH/NINDS
    Unglued Glia, a Seven Transmembrane Protein Essential for Glia Differentiation
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. DeDecker BS. The Polymerase Step Reaction (PSR) Method for Gene and Library Synthesis. Methods Mol Biol. 2017; 1472:129-38. PMID: 27671937.
      View in: PubMed
    2. Lee ZB, Firnhaber C, Clarke J, DeDecker BS. Gene and library synthesis without amplification: polymerase step reaction (PSR). Biotechniques. 2015 Sep; 59(3):163-6. PMID: 26345510.
      View in: PubMed
    3. Mourikis P, Lake RJ, Firnhaber CB, DeDecker BS. Modifiers of notch transcriptional activity identified by genome-wide RNAi. BMC Dev Biol. 2010 Oct 19; 10:107. PMID: 20959007; PMCID: PMC2976970.
    4. De Wall SL, Painter C, Stone JD, Bandaranayake R, Wiley DC, Mitchison TJ, Stern LJ, DeDecker BS. Noble metals strip peptides from class II MHC proteins. Nat Chem Biol. 2006 Apr; 2(4):197-201. PMID: 16505807.
      View in: PubMed
    5. Venkatesh N, Feng Y, DeDecker B, Yacono P, Golan D, Mitchison T, McKeon F. Chemical genetics to identify NFAT inhibitors: potential of targeting calcium mobilization in immunosuppression. Proc Natl Acad Sci U S A. 2004 Jun 15; 101(24):8969-74. PMID: 15184684; PMCID: PMC428456.
    6. Friedler A, DeDecker BS, Freund SM, Blair C, RĂ¼diger S, Fersht AR. Structural distortion of p53 by the mutation R249S and its rescue by a designed peptide: implications for "mutant conformation". J Mol Biol. 2004 Feb 06; 336(1):187-96. PMID: 14741214.
      View in: PubMed
    7. DeDecker BS. Allosteric drugs: thinking outside the active-site box. Chem Biol. 2000 May; 7(5):R103-7. PMID: 10801477.
      View in: PubMed
    8. Nikolova PV, Wong KB, DeDecker B, Henckel J, Fersht AR. Mechanism of rescue of common p53 cancer mutations by second-site suppressor mutations. EMBO J. 2000 Feb 01; 19(3):370-8. PMID: 10654936; PMCID: PMC305574.
    9. Wong KB, DeDecker BS, Freund SM, Proctor MR, Bycroft M, Fersht AR. Hot-spot mutants of p53 core domain evince characteristic local structural changes. Proc Natl Acad Sci U S A. 1999 Jul 20; 96(15):8438-42. PMID: 10411893; PMCID: PMC17534.
    10. O'Brien R, DeDecker B, Fleming KG, Sigler PB, Ladbury JE. The effects of salt on the TATA binding protein-DNA interaction from a hyperthermophilic archaeon. J Mol Biol. 1998 May 29; 279(1):117-25. PMID: 9636704.
      View in: PubMed
    11. Bullock AN, Henckel J, DeDecker BS, Johnson CM, Nikolova PV, Proctor MR, Lane DP, Fersht AR. Thermodynamic stability of wild-type and mutant p53 core domain. Proc Natl Acad Sci U S A. 1997 Dec 23; 94(26):14338-42. PMID: 9405613; PMCID: PMC24967.
    12. Kosa PF, Ghosh G, DeDecker BS, Sigler PB. The 2.1-A crystal structure of an archaeal preinitiation complex: TATA-box-binding protein/transcription factor (II)B core/TATA-box. Proc Natl Acad Sci U S A. 1997 Jun 10; 94(12):6042-7. PMID: 9177165; PMCID: PMC20997.
    13. DeDecker BS, O'Brien R, Fleming PJ, Geiger JH, Jackson SP, Sigler PB. The crystal structure of a hyperthermophilic archaeal TATA-box binding protein. J Mol Biol. 1996 Dec 20; 264(5):1072-84. PMID: 9000631.
      View in: PubMed
    14. Han M, DeDecker BS, Smith SO. Localization of the retinal protonated Schiff base counterion in rhodopsin. Biophys J. 1993 Aug; 65(2):899-906. PMID: 8105993; PMCID: PMC1225790.
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