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Lawrence D Horwitz

TitleElectronic Research Admin
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-MED

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    R01HL024763     (HORWITZ, LAWRENCE)Mar 1, 1979 - Mar 31, 1987
    NIH/NHLBI
    LEFT VENTRICULAR FUNCTION IN EXERCISE
    Role: Principal Investigator

    T32HL007459     (HORWITZ, LAWRENCE)Jul 1, 1980 - Jun 30, 1990
    NIH/NHLBI
    CARDIOVASCULAR RESEARCH
    Role: Principal Investigator

    R01HL041661     (HORWITZ, LAWRENCE)Dec 1, 1988 - Nov 30, 1993
    NIH/NHLBI
    REPERFUSION INJURY TO CORONARY ENDOTHELIUM
    Role: Principal Investigator

    R01HL048177     (HORWITZ, LAWRENCE)May 1, 1992 - Apr 30, 1996
    NIH/NHLBI
    MECHANISMS OF MYOCARDIAL REPERFUSION INJURY
    Role: Principal Investigator

    R01HL055291     (HORWITZ, LAWRENCE)Feb 1, 1996 - Jan 31, 2008
    NIH/NHLBI
    Iron-Mediated Cardiovascular Injury
    Role: Principal Investigator

    R41DK072644     (HORWITZ, LAWRENCE)Sep 5, 2005 - Aug 31, 2007
    NIH/NIDDK
    BUCILLAMINE AND RADIOCONTRAST - INDUCED NEPHROPATHY
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Horwitz LD, Horwitz MA. The exochelins of pathogenic mycobacteria: unique, highly potent, lipid- and water-soluble hexadentate iron chelators with multiple potential therapeutic uses. Antioxid Redox Signal. 2014 Dec 01; 21(16):2246-61. PMID: 24684595; PMCID: PMC4224048.
    2. Ambler SK, Hodges YK, Jones GM, Long CS, Horwitz LD. Prolonged administration of a dithiol antioxidant protects against ventricular remodeling due to ischemia-reperfusion in mice. Am J Physiol Heart Circ Physiol. 2008 Sep; 295(3):H1303-H1310. PMID: 18689493; PMCID: PMC2544508.
    3. Anwar A, Gu M, Brady S, Qamar L, Behbakht K, Shellman YG, Agarwal R, Norris DA, Horwitz LD, Fujita M. Photoprotective effects of bucillamine against UV-induced damage in an SKH-1 hairless mouse model. Photochem Photobiol. 2008 Mar-Apr; 84(2):477-83. PMID: 18266821.
      View in: PubMed
    4. Pahl PM, Reese SM, Horwitz LD. A lipid-soluble iron chelator alters cell cycle regulatory protein binding in breast cancer cells compared to normal breast cells. J Exp Ther Oncol. 2007; 6(3):193-200. PMID: 17552359.
      View in: PubMed
    5. Hodges YK, Weinberger HD, Stephens J, Horwitz MA, Horwitz LD. Desferri-Exochelin, a lipid-soluble, hexadentate iron chelator, effectively removes tissue iron. Transl Res. 2006 Aug; 148(2):63-71. PMID: 16890146.
      View in: PubMed
    6. Lindenfeld J, Weil JV, Travis VL, Horwitz LD. Regulation of oxygen delivery during induced polycythemia in exercising dogs. Am J Physiol Heart Circ Physiol. 2005 Nov; 289(5):H1821-5. PMID: 16006540.
      View in: PubMed
    7. Hodges YK, Reese SM, Pahl PM, Horwitz LD. Paradoxical effects of iron chelation on growth of vascular endothelial cells. J Cardiovasc Pharmacol. 2005 Jun; 45(6):539-44. PMID: 15897780.
      View in: PubMed
    8. Pahl PM, Horwitz LD. Cell permeable iron chelators as potential cancer chemotherapeutic agents. Cancer Invest. 2005; 23(8):683-91. PMID: 16377587.
      View in: PubMed
    9. Hodges YK, Antholine WE, Horwitz LD. Effect on ribonucleotide reductase of novel lipophilic iron chelators: the desferri-exochelins. Biochem Biophys Res Commun. 2004 Mar 12; 315(3):595-8. PMID: 14975742.
      View in: PubMed
    10. Horwitz LD. Bucillamine: a potent thiol donor with multiple clinical applications. Cardiovasc Drug Rev. 2003; 21(2):77-90. PMID: 12847560.
      View in: PubMed
    11. Chong TW, Horwitz LD, Moore JW, Sowter HM, Harris AL. A mycobacterial iron chelator, desferri-exochelin, induces hypoxia-inducible factors 1 and 2, NIP3, and vascular endothelial growth factor in cancer cell lines. Cancer Res. 2002 Dec 01; 62(23):6924-7. PMID: 12460908.
      View in: PubMed
    12. Amersi F, Nelson SK, Shen XD, Kato H, Melinek J, Kupiec-Weglinski JW, Horwitz LD, Busuttil RW, Horwitz MA. Bucillamine, a thiol antioxidant, prevents transplantation-associated reperfusion injury. Proc Natl Acad Sci U S A. 2002 Jun 25; 99(13):8915-20. PMID: 12084933; PMCID: PMC124398.
    13. Whitekus MJ, Li N, Zhang M, Wang M, Horwitz MA, Nelson SK, Horwitz LD, Brechun N, Diaz-Sanchez D, Nel AE. Thiol antioxidants inhibit the adjuvant effects of aerosolized diesel exhaust particles in a murine model for ovalbumin sensitization. J Immunol. 2002 Mar 01; 168(5):2560-7. PMID: 11859152.
      View in: PubMed
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