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Pierre Andre Moine

TitleAssociate Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-Anesthesiology
Phone720/848-3278

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Moine P, Mueller SW, Schoen JA, Rothchild KB, Fish DN. Pharmacokinetic and Pharmacodynamic Evaluation of a Weight-Based Dosing Regimen of Cefoxitin for Perioperative Surgical Prophylaxis in Obese and Morbidly Obese Patients. Antimicrob Agents Chemother. 2016 Oct; 60(10):5885-93. PMID: 27458209.
      View in: PubMed
    2. Neto AS, Hemmes SN, Barbas CS, Beiderlinden M, Fernandez-Bustamante A, Futier E, Gajic O, El-Tahan MR, Ghamdi AA, Günay E, Jaber S, Kokulu S, Kozian A, Licker M, Lin WQ, Maslow AD, Memtsoudis SG, Reis Miranda D, Moine P, Ng T, Paparella D, Ranieri VM, Scavonetto F, Schilling T, Selmo G, Severgnini P, Sprung J, Sundar S, Talmor D, Treschan T, Unzueta C, Weingarten TN, Wolthuis EK, Wrigge H, Amato MB, Costa EL, de Abreu MG, Pelosi P, Schultz MJ. Association between driving pressure and development of postoperative pulmonary complications in patients undergoing mechanical ventilation for general anaesthesia: a meta-analysis of individual patient data. Lancet Respir Med. 2016 Apr; 4(4):272-80. PMID: 26947624.
      View in: PubMed
    3. Serpa Neto A, Hemmes SN, Barbas CS, Beiderlinden M, Biehl M, Binnekade JM, Canet J, Fernandez-Bustamante A, Futier E, Gajic O, Hedenstierna G, Hollmann MW, Jaber S, Kozian A, Licker M, Lin WQ, Maslow AD, Memtsoudis SG, Reis Miranda D, Moine P, Ng T, Paparella D, Putensen C, Ranieri M, Scavonetto F, Schilling T, Schmid W, Selmo G, Severgnini P, Sprung J, Sundar S, Talmor D, Treschan T, Unzueta C, Weingarten TN, Wolthuis EK, Wrigge H, Gama de Abreu M, Pelosi P, Schultz MJ. Protective versus Conventional Ventilation for Surgery: A Systematic Review and Individual Patient Data Meta-analysis. Anesthesiology. 2015 Jul; 123(1):66-78. PMID: 25978326.
      View in: PubMed
    4. Fernandez-Bustamante A, Hashimoto S, Serpa Neto A, Moine P, Vidal Melo MF, Repine JE. Perioperative lung protective ventilation in obese patients. BMC Anesthesiol. 2015 May 06; 15:56. PMID: 25907273; PMCID: PMC4491899.
    5. Serpa Neto A, Hemmes SN, Barbas CS, Beiderlinden M, Fernandez-Bustamante A, Futier E, Hollmann MW, Jaber S, Kozian A, Licker M, Lin WQ, Moine P, Scavonetto F, Schilling T, Selmo G, Severgnini P, Sprung J, Treschan T, Unzueta C, Weingarten TN, Wolthuis EK, Wrigge H, Gama de Abreu M, Pelosi P, Schultz MJ. Incidence of mortality and morbidity related to postoperative lung injury in patients who have undergone abdominal or thoracic surgery: a systematic review and meta-analysis. Lancet Respir Med. 2014 Dec; 2(12):1007-15. PMID: 25466352.
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    6. Asehnoune K, Moine P. Protease-activated receptor-1: key player in the sepsis coagulation-inflammation crosstalk. Crit Care. 2013 Feb 26; 17(1):119. PMID: 23448515; PMCID: PMC4057503.
    7. Moine P, Fish DN. Pharmacodynamic modelling of intravenous antibiotic prophylaxis in elective colorectal surgery. Int J Antimicrob Agents. 2013 Feb; 41(2):167-73. PMID: 23182539.
      View in: PubMed
    8. Fernandez-Bustamante A, Wood CL, Tran ZV, Moine P. Intraoperative ventilation: incidence and risk factors for receiving large tidal volumes during general anesthesia. BMC Anesthesiol. 2011 Nov 21; 11:22. PMID: 22103561; PMCID: PMC3235523.
    9. Darmon M, Azoulay E, Fulgencio JP, Garrigues B, Gouzes C, Moine P, Villers D, Teboul V, le Gall JR, Chevret S. Procedure volume is one determinant of centre effect in mechanically ventilated patients. Eur Respir J. 2011 Feb; 37(2):364-70. PMID: 20595153.
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    10. Moine P, Bédos JP. Methicillin-resistant Staphylococcus aureus pneumonia treatment: do not confuse pharmacokinetics and pharmacodynamics. Chest. 2007 Sep; 132(3):1101, author reply 1102-3. PMID: 17873216.
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    11. Moine P, Asehnoune K. Antibiotic prophylaxis in colorectal surgery. N Engl J Med. 2007 Apr 19; 356(16):1684; author reply 1685. PMID: 17442916.
      View in: PubMed
    12. Mohler J, Moine P, Azoulay-Dupuis E, Henin D, Fantin B. Polyvalent 23 epitope polysaccharide pneumonia vaccine induced effective protection through strain-adapted effector mechanisms as demonstrated by the different cytokine responses in mice challenged with two different strains of Streptococcus pneumoniae. Eur Cytokine Netw. 2007 Mar; 18(1):23-30. PMID: 17400535.
      View in: PubMed
    13. Moine P. [Potential benefits of non-anti-infective treatments of septic shock: a critical analysis of literature]. Ann Fr Anesth Reanim. 2007 Apr; 26(4):370-5. PMID: 17395418.
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    14. Abgueguen P, Azoulay-Dupuis E, Noel V, Moine P, Rieux V, Fantin B, Bedos JP. Amoxicillin is effective against penicillin-resistant Streptococcus pneumoniae strains in a mouse pneumonia model simulating human pharmacokinetics. Antimicrob Agents Chemother. 2007 Jan; 51(1):208-14. PMID: 17060515; PMCID: PMC1797644.
    15. Villers D, Fulgencio JP, Gouzes C, Hémery F, Blériot JP, Garrigues B, Le Gall JR, Lepage E, Moine P, Teboul V. [ICU performance: results of a French study involving 80,000 ICU stays]. Ann Fr Anesth Reanim. 2006 Nov-Dec; 25(11-12):1111-8. PMID: 17029679.
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    16. Asehnoune K, Fitting C, Edouard AR, Minville V, Benhamou D, Cavaillon JM, Moine P. beta2-Adrenoceptor blockade partially restores ex vivo TNF production following hemorrhagic shock. Cytokine. 2006 May; 34(3-4):212-8. PMID: 16790355.
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    17. Hoen S, Mazoit JX, Asehnoune K, Brailly-Tabard S, Benhamou D, Moine P, Edouard AR. Hydrocortisone increases the sensitivity to alpha1-adrenoceptor stimulation in humans following hemorrhagic shock. Crit Care Med. 2005 Dec; 33(12):2737-43. PMID: 16352953.
      View in: PubMed
    18. Asehnoune K, Fitting C, Edouard AR, Cosson C, Benhamou D, Cavaillon JM, Moine P. Influence of resuscitation volume on blood cells TNF production in a murine model of haemorrhage. Resuscitation. 2006 Jan; 68(1):127-33. PMID: 16219409.
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    19. Le Gall JR, Neumann A, Hemery F, Bleriot JP, Fulgencio JP, Garrigues B, Gouzes C, Lepage E, Moine P, Villers D. Mortality prediction using SAPS II: an update for French intensive care units. Crit Care. 2005; 9(6):R645-52. PMID: 16280063; PMCID: PMC1414016.
    20. Moine P, Bédos JP. Levofloxacin for treatment of ventilator-associated pneumonia: putting the cart before the horse. Clin Infect Dis. 2005 Aug 01; 41(3):414-5; author reply 415-6. PMID: 16007546.
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    21. Beloeil H, Asehnoune K, Moine P, Benhamou D, Mazoit JX. Bupivacaine's action on the carrageenan-induced inflammatory response in mice: cytokine production by leukocytes after ex-vivo stimulation. Anesth Analg. 2005 Apr; 100(4):1081-6. PMID: 15781526.
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    22. Azoulay-Dupuis E, Bédos JP, Mohler J, Moine P, Cherbuliez C, Peytavin G, Fantin B, Köhler T. Activity of gemifloxacin against quinolone-resistant Streptococcus pneumoniae strains in vitro and in a mouse pneumonia model. Antimicrob Agents Chemother. 2005 Mar; 49(3):1046-54. PMID: 15728901; PMCID: PMC549237.
    23. Asehnoune K, Moine P, Fitting C, Benhamou D, Cavaillon JM, Edouard A. [Differential modulation of TLR2 and TLR4-induced TNF production by murin haemorrhagic shock]. Ann Fr Anesth Reanim. 2005 Mar; 24(3):255-9. PMID: 15792558.
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    24. L'Hériteau F, Alberti C, Cohen Y, Troché G, Moine P, Timsit JF. Nosocomial infection and multidrug-resistant bacteria surveillance in intensive care units: a survey in France. Infect Control Hosp Epidemiol. 2005 Jan; 26(1):13-20. PMID: 15693404.
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    25. Moine P, Abraham E. Immunomodulation and sepsis: impact of the pathogen. Shock. 2004 Oct; 22(4):297-308. PMID: 15377883.
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    26. Azoulay E, Cohen Y, Zahar JR, Garrouste-Orgeas M, Adrie C, Moine P, de Lassence A, Timsit JF. Practices in non-neutropenic ICU patients with Candida-positive airway specimens. Intensive Care Med. 2004 Jul; 30(7):1384-9. PMID: 15148568.
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    27. Azoulay-Dupuis E, Bédos JP, Mohler J, Peytavin G, Isturiz R, Moine P, Rieux V, Cherbuliez C, Péchère JC, Fantin B, Köhler T. Activities of garenoxacin against quinolone-resistant Streptococcus pneumoniae strains in vitro and in a mouse pneumonia model. Antimicrob Agents Chemother. 2004 Mar; 48(3):765-73. PMID: 14982762; PMCID: PMC353052.
    28. Moine P, Hémery F, Blériot JP, Fulgencio JP, Garrigues B, Gouzes C, Le Gall JR, Lepage E, Villers D. [Completeness of ICU activity reports sent to French healthcare authorities]. Ann Fr Anesth Reanim. 2004 Feb; 23(1):15-20. PMID: 14980319.
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    29. Gauzit R, Lepape A, Moine P. [Nosocomial urinary tract infection]. Ann Fr Anesth Reanim. 2004 Feb; 23(1):3-5. PMID: 14980317.
      View in: PubMed
    30. Adib-Conquy M, Moine P, Asehnoune K, Edouard A, Espevik T, Miyake K, Werts C, Cavaillon JM. Toll-like receptor-mediated tumor necrosis factor and interleukin-10 production differ during systemic inflammation. Am J Respir Crit Care Med. 2003 Jul 15; 168(2):158-64. PMID: 12738604.
      View in: PubMed
    31. Mohler J, Azoulay-Dupuis E, Amory-Rivier C, Mazoit JX, Bédos JP, Rieux V, Moine P. Streptococcus pneumoniae strain-dependent lung inflammatory responses in a murine model of pneumococcal pneumonia. Intensive Care Med. 2003 May; 29(5):808-16. PMID: 12665994.
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    32. Azoulay E, Adrie C, De Lassence A, Pochard F, Moreau D, Thiery G, Cheval C, Moine P, Garrouste-Orgeas M, Alberti C, Cohen Y, Timsit JF. Determinants of postintensive care unit mortality: a prospective multicenter study. Crit Care Med. 2003 Feb; 31(2):428-32. PMID: 12576947.
      View in: PubMed
    33. Hoen S, Asehnoune K, Brailly-Tabard S, Mazoit JX, Benhamou D, Moine P, Edouard AR. Cortisol response to corticotropin stimulation in trauma patients: influence of hemorrhagic shock. Anesthesiology. 2002 Oct; 97(4):807-13. PMID: 12357144.
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    34. Montravers P, Veber B, Auboyer C, Dupont H, Gauzit R, Korinek AM, Malledant Y, Martin C, Moine P, Pourriat JL. Diagnostic and therapeutic management of nosocomial pneumonia in surgical patients: results of the Eole study. Crit Care Med. 2002 Feb; 30(2):368-75. PMID: 11889312.
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    35. Moine P, Timsit JF, De Lassence A, Troché G, Fosse JP, Alberti C, Cohen Y. Mortality associated with late-onset pneumonia in the intensive care unit: results of a multi-center cohort study. Intensive Care Med. 2002 Feb; 28(2):154-63. PMID: 11907658.
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    36. Azoulay E, Moine P, Cohen Y, Timsit JF. [Nosocomial pneumopathy acquired under mechanical ventilation. Suspicion criteria, bacteriologic diagnosis, and remission criteria]. Rev Pneumol Clin. 2001 Dec; 57(6):380-90. PMID: 11924147.
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    37. Albaladejo P, Caillet B, Moine P, Vigué B, Decorps-Declère A, Benhamou D. [Off-label prescriptions in an adult surgical intensive care unit]. Presse Med. 2001 Oct 20; 30(30):1484-8. PMID: 11712205.
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    38. Adib-Conquy M, Asehnoune K, Moine P, Cavaillon JM. Long-term-impaired expression of nuclear factor-kappa B and I kappa B alpha in peripheral blood mononuclear cells of trauma patients. J Leukoc Biol. 2001 Jul; 70(1):30-8. PMID: 11435482.
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    39. Timsit JF, Fosse JP, Troché G, De Lassence A, Alberti C, Garrouste-Orgeas M, Azoulay E, Chevret S, Moine P, Cohen Y. Accuracy of a composite score using daily SAPS II and LOD scores for predicting hospital mortality in ICU patients hospitalized for more than 72 h. Intensive Care Med. 2001 Jun; 27(6):1012-21. PMID: 11497133.
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    40. Adib-Conquy M, Adrie C, Moine P, Asehnoune K, Fitting C, Pinsky MR, Dhainaut JF, Cavaillon JM. NF-kappaB expression in mononuclear cells of patients with sepsis resembles that observed in lipopolysaccharide tolerance. Am J Respir Crit Care Med. 2000 Nov; 162(5):1877-83. PMID: 11069829.
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    41. Amory-Rivier CF, Mohler J, Bédos JP, Azoulay-Dupuis E, Henin D, Muffat-Joly M, Carbon C, Moine P. Nuclear factor-kappaB activation in mouse lung lavage cells in response to Streptococcus pneumoniae pulmonary infection. Crit Care Med. 2000 Sep; 28(9):3249-56. PMID: 11008989.
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    42. Azoulay-Dupuis E, Rieux V, Muffat-Joly M, Bédos JP, Vallée E, Rivier C, Isturiz R, Carbon C, Moine P. Relationship between capsular type, penicillin susceptibility, and virulence of human Streptococcus pneumoniae isolates in mice. Antimicrob Agents Chemother. 2000 Jun; 44(6):1575-7. PMID: 10817711; PMCID: PMC89915.
    43. Albaladejo P, Mann C, Moine P, Panzani M, Ribeyrolles D, Lethellier P, Bernard I, Duranteau J, Benhamou D. [Impact of an information booklet on patient satisfaction in anesthesia]. Ann Fr Anesth Reanim. 2000 Apr; 19(4):242-8. PMID: 10836108.
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    44. Dupont H, Mentec H, Cheval C, Moine P, Fierobe L, Timsit JF. Short-term effect of inhaled nitric oxide and prone positioning on gas exchange in patients with severe acute respiratory distress syndrome. Crit Care Med. 2000 Feb; 28(2):304-8. PMID: 10708157.
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    45. Moine P, McIntyre R, Schwartz MD, Kaneko D, Shenkar R, Le Tulzo Y, Moore EE, Abraham E. NF-kappaB regulatory mechanisms in alveolar macrophages from patients with acute respiratory distress syndrome. Shock. 2000 Feb; 13(2):85-91. PMID: 10670837.
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    46. Moine P, Mazoit JX. Streptococcus pneumoniae pneumonia in mice: optimal amoxicillin dosing predicted from a pharmacokinetic-pharmacodynamic model. J Pharmacol Exp Ther. 1999 Dec; 291(3):1086-92. PMID: 10565828.
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    47. Dupont H, Le Corre F, Fierobe L, Cheval C, Moine P, Timsit JF. Efficiency of inhaled nitric oxide as rescue therapy during severe ARDS: survival and factors associated with the first response. J Crit Care. 1999 Sep; 14(3):107-13. PMID: 10527247.
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    48. Bédos JP, Rivier C, Azoulay-Dupuis E, Moine P. [Current microbiologic problems. Pulmonary infection by Streptococcus pneumoniae. Current physiopathological aspects]. Presse Med. 1999 Feb 27; 28(8):442-9. PMID: 10093606.
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    49. Benoit G, Decaux A, Eschwège P, Descorps Declere A, Moine P, Blanchet P, Coulomb F, Brivet F, Decaris J, Joseph L, Devictor D, Richard C, Gillot C, Huault G. [Organ procurement from cardiac arrest donors: outcome of kidney grafts and recommendations]. Presse Med. 1999 Jan 09; 28(1):3-7. PMID: 9951502.
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    50. Bédos JP, Azoulay-Dupuis E, Moine P, Muffat-Joly M, Veber B, Pocidalo JJ, Vallée E. Pharmacodynamic activities of ciprofloxacin and sparfloxacin in a murine pneumococcal pneumonia model: relevance for drug efficacy. J Pharmacol Exp Ther. 1998 Jul; 286(1):29-35. PMID: 9655838.
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    51. Troché G, Moine P. Is the duration of mechanical ventilation predictable? Chest. 1997 Sep; 112(3):745-51. PMID: 9315810.
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    52. Moine P, Shenkar R, Kaneko D, Le Tulzo Y, Abraham E. Systemic blood loss affects NF-kappa B regulatory mechanisms in the lungs. Am J Physiol. 1997 Jul; 273(1 Pt 1):L185-92. PMID: 9252555.
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    53. Le Tulzo Y, Shenkar R, Kaneko D, Moine P, Fantuzzi G, Dinarello CA, Abraham E. Hemorrhage increases cytokine expression in lung mononuclear cells in mice: involvement of catecholamines in nuclear factor-kappaB regulation and cytokine expression. J Clin Invest. 1997 Apr 01; 99(7):1516-24. PMID: 9119995; PMCID: PMC507971.
    54. Moine P, Sauve C, Vallee E, Bedos JP, Azoulay-Dupuis E. In vivo efficacy of cefotaxime and amoxicillin against penicillin-susceptible, penicillin-resistant and penicillin---cephalosporin-resistant strains of Streptococcus pneumoniae in a mouse pneumonia model. Clin Microbiol Infect. 1997 Feb; 3(6):608-615. PMID: 11864201.
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    55. Moine P, Mazoit JX, Bédos JP, Vallée E, Azoulay-Dupuis E. Correlation between in vitro and in vivo activity of amoxicillin against Streptococcus pneumoniae in a murine pneumonia model. J Pharmacol Exp Ther. 1997 Jan; 280(1):310-5. PMID: 8996211.
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    56. Sauve C, Azoulay-Dupuis E, Moine P, Darras-Joly C, Rieux V, Carbon C, Bédos JP. Efficacies of cefotaxime and ceftriaxone in a mouse model of pneumonia induced by two penicillin- and cephalosporin-resistant strains of Streptococcus pneumoniae. Antimicrob Agents Chemother. 1996 Dec; 40(12):2829-34. PMID: 9124850; PMCID: PMC163631.
    57. Darras-Joly C, Bédos JP, Sauve C, Moine P, Vallée E, Carbon C, Azoulay-Dupuis E. Synergy between amoxicillin and gentamicin in combination against a highly penicillin-resistant and -tolerant strain of Streptococcus pneumoniae in a mouse pneumonia model. Antimicrob Agents Chemother. 1996 Sep; 40(9):2147-51. PMID: 8878597; PMCID: PMC163489.
    58. Schwartz MD, Moore EE, Moore FA, Shenkar R, Moine P, Haenel JB, Abraham E. Nuclear factor-kappa B is activated in alveolar macrophages from patients with acute respiratory distress syndrome. Crit Care Med. 1996 Aug; 24(8):1285-92. PMID: 8706481.
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    59. Azoulay-Dupuis E, Moine P, Bedos JP, Rieux V, Vallee E. Amoxicillin dose-effect relationship with Streptococcus pneumoniae in a mouse pneumonia model and roles of in vitro penicillin susceptibilities, autolysis, and tolerance properties of the strains. Antimicrob Agents Chemother. 1996 Apr; 40(4):941-6. PMID: 8849256; PMCID: PMC163235.
    60. Sicsic JC, Jugan E, Moine P, Edouard A, Samii K. Reversible hepatic cytolysis during almitrine bismesylate treatment for posttraumatic ARDS. Intensive Care Med. 1996 Feb; 22(2):173-4. PMID: 8857125.
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    61. Moine P, Vercken JB, Chevret S, Gajdos P. Severe community-acquired pneumococcal pneumonia. The French Study Group of Community-Acquired Pneumonia in ICU. Scand J Infect Dis. 1995; 27(3):201-6. PMID: 8539541.
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    62. Moine P, Vallée E, Azoulay-Dupuis E, Bourget P, Bédos JP, Bauchet J, Pocidalo JJ. In vivo efficacy of a broad-spectrum cephalosporin, ceftriaxone, against penicillin-susceptible and -resistant strains of Streptococcus pneumoniae in a mouse pneumonia model. Antimicrob Agents Chemother. 1994 Sep; 38(9):1953-8. PMID: 7811003; PMCID: PMC284667.
    63. Moine P, Vercken JB, Chevret S, Chastang C, Gajdos P. Severe community-acquired pneumonia. Etiology, epidemiology, and prognosis factors. French Study Group for Community-Acquired Pneumonia in the Intensive Care Unit. Chest. 1994 May; 105(5):1487-95. PMID: 8181342.
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    64. Moine P, Ecoffey C. [Caudal block in children: analgesia and respiratory effect of the combination bupivacaine-fentanyl]. Ann Fr Anesth Reanim. 1992; 11(2):141-4. PMID: 1503285.
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    65. Moine P, Ecoffey C. [Analgesia and respiratory effects after caudal anesthesia with a bupivacaine-fentanyl combination in the child]. Ann Fr Anesth Reanim. 1989; 8 Suppl:R71. PMID: 2604259.
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