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Robert S. Stearman

TitleAssociate Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-MED
Address2RC2
Research 2
12700 East 19th Avenue - Mail Stop 8619
Aurora CO 80045
Phone303/724-6091

     Bibliographic 
     selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Stearman RS, Cornelius AR, Lu X, Conklin DS, Del Rosario MJ, Lowe AM, Elos MT, Fettig LM, Wong RE, Hara N, Cogan JD, Phillips JA, Taylor MR, Graham BB, Tuder RM, Loyd JE, Geraci MW. Functional prostacyclin synthase promoter polymorphisms. Impact in pulmonary arterial hypertension. Am J Respir Crit Care Med. 2014 May 1; 189(9):1110-20.
      View in: PubMed
    2. Nakachi I, Rice JL, Coldren CD, Edwards MG, Stearman RS, Glidewell SC, Varella-Garcia M, Franklin WA, Keith RL, Lewis MT, Gao B, Merrick DT, Miller YE, Geraci MW. Application of SNP microarrays to the genome-wide analysis of chromosomal instability in premalignant airway lesions. Cancer Prev Res (Phila). 2014 Feb; 7(2):255-65.
      View in: PubMed
    3. Reisdorph N, Stearman R, Kechris K, Phang TL, Reisdorph R, Prenni J, Erle DJ, Coldren C, Schey K, Nesvizhskii A, Geraci M. Hands-on workshops as an effective means of learning advanced technologies including genomics, proteomics and bioinformatics. Genomics Proteomics Bioinformatics. 2013 Dec; 11(6):368-77.
      View in: PubMed
    4. Maloney JP, Stearman RS, Bull TM, Calabrese DW, Tripp-Addison ML, Wick MJ, Broeckel U, Robbins IM, Wheeler LA, Cogan JD, Loyd JE. Loss-of-function thrombospondin-1 mutations in familial pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2012 Mar 15; 302(6):L541-54.
      View in: PubMed
    5. Nemenoff R, Meyer AM, Hudish TM, Mozer AB, Snee A, Narumiya S, Stearman RS, Winn RA, Weiser-Evans M, Geraci MW, Keith RL. Prostacyclin prevents murine lung cancer independent of the membrane receptor by activation of peroxisomal proliferator--activated receptor gamma. Cancer Prev Res (Phila). 2008 Oct; 1(5):349-56.
      View in: PubMed
    6. Stearman RS, Dwyer-Nield L, Grady MC, Malkinson AM, Geraci MW. A macrophage gene expression signature defines a field effect in the lung tumor microenvironment. Cancer Res. 2008 Jan 1; 68(1):34-43.
      View in: PubMed
    7. Bren-Mattison Y, Meyer AM, Van Putten V, Li H, Kuhn K, Stearman R, Weiser-Evans M, Winn RA, Heasley LE, Nemenoff RA. Antitumorigenic effects of peroxisome proliferator-activated receptor-gamma in non-small-cell lung cancer cells are mediated by suppression of cyclooxygenase-2 via inhibition of nuclear factor-kappaB. Mol Pharmacol. 2008 Mar; 73(3):709-17.
      View in: PubMed
    8. Wang W, Zolty E, Falk S, Summer S, Stearman R, Geraci M, Schrier R. Prostacyclin in endotoxemia-induced acute kidney injury: cyclooxygenase inhibition and renal prostacyclin synthase transgenic mice. Am J Physiol Renal Physiol. 2007 Oct; 293(4):F1131-6.
      View in: PubMed
    9. Stearman RS, Grady MC, Nana-Sinkam P, Varella-Garcia M, Geraci MW. Genetic and epigenetic regulation of the human prostacyclin synthase promoter in lung cancer cell lines. Mol Cancer Res. 2007 Mar; 5(3):295-308.
      View in: PubMed
    10. Nana-Sinkam SP, Lee JD, Sotto-Santiago S, Stearman RS, Keith RL, Choudhury Q, Cool C, Parr J, Moore MD, Bull TM, Voelkel NF, Geraci MW. Prostacyclin prevents pulmonary endothelial cell apoptosis induced by cigarette smoke. Am J Respir Crit Care Med. 2007 Apr 1; 175(7):676-85.
      View in: PubMed
    11. Nana-Sinkam SP, Lee JD, Stearman R, Sakao S, Sotto-Santiago S, Voelkel NF, Geraci MW. Prostacyclin synthase in smoking-related lung disease. Proc Am Thorac Soc. 2006 Aug; 3(6):517.
      View in: PubMed
    12. Stearman RS, Dwyer-Nield L, Zerbe L, Blaine SA, Chan Z, Bunn PA, Johnson GL, Hirsch FR, Merrick DT, Franklin WA, Baron AE, Keith RL, Nemenoff RA, Malkinson AM, Geraci MW. Analysis of orthologous gene expression between human pulmonary adenocarcinoma and a carcinogen-induced murine model. Am J Pathol. 2005 Dec; 167(6):1763-75.
      View in: PubMed
    13. Nana-Sinkam P, Oyer RJ, Stearman RS, Sotto-Santiago S, Moore MD, Bull TM, Grady MC, Choudhery Q, Nemenoff RA, Lane K, Loyd JE, Geraci MW. Prostacyclin synthase promoter regulation and familial pulmonary arterial hypertension. Chest. 2005 Dec; 128(6 Suppl):612S.
      View in: PubMed
    14. Brower CS, Sato S, Tomomori-Sato C, Kamura T, Pause A, Stearman R, Klausner RD, Malik S, Lane WS, Sorokina I, Roeder RG, Conaway JW, Conaway RC. Mammalian mediator subunit mMED8 is an Elongin BC-interacting protein that can assemble with Cul2 and Rbx1 to reconstitute a ubiquitin ligase. Proc Natl Acad Sci U S A. 2002 Aug 6; 99(16):10353-8.
      View in: PubMed
    15. Bindra RS, Vasselli JR, Stearman R, Linehan WM, Klausner RD. VHL-mediated hypoxia regulation of cyclin D1 in renal carcinoma cells. Cancer Res. 2002 Jun 1; 62(11):3014-9.
      View in: PubMed
    16. Loyevsky M, LaVaute T, Allerson CR, Stearman R, Kassim OO, Cooperman S, Gordeuk VR, Rouault TA. An IRP-like protein from Plasmodium falciparum binds to a mammalian iron-responsive element. Blood. 2001 Oct 15; 98(8):2555-62.
      View in: PubMed
    17. Carmel-Harel O, Stearman R, Gasch AP, Botstein D, Brown PO, Storz G. Role of thioredoxin reductase in the Yap1p-dependent response to oxidative stress in Saccharomyces cerevisiae. Mol Microbiol. 2001 Feb; 39(3):595-605.
      View in: PubMed
    18. Pause A, Peterson B, Schaffar G, Stearman R, Klausner RD. Studying interactions of four proteins in the yeast two-hybrid system: structural resemblance of the pVHL/elongin BC/hCUL-2 complex with the ubiquitin ligase complex SKP1/cullin/F-box protein. Proc Natl Acad Sci U S A. 1999 Aug 17; 96(17):9533-8.
      View in: PubMed
    19. Yamaguchi-Iwai Y, Stearman R, Dancis A, Klausner RD. Iron-regulated DNA binding by the AFT1 protein controls the iron regulon in yeast. EMBO J. 1996 Jul 1; 15(13):3377-84.
      View in: PubMed
    20. Taylor J, Stearman RS, Uratani BB. Development of a native plasmid as a cloning vector in Clavibacter xyli subsp. cynodontis. Plasmid. 1993 May; 29(3):241-4.
      View in: PubMed
    21. Turner JT, Lampel JS, Stearman RS, Sundin GW, Gunyuzlu P, Anderson JJ. Stability of the delta-endotoxin gene from Bacillus thuringiensis subsp. kurstaki in a recombinant strain of Clavibacter xyli subsp. cynodontis. Appl Environ Microbiol. 1991 Dec; 57(12):3522-8.
      View in: PubMed
    22. Stearman RS, Frankel AD, Freire E, Liu BS, Pabo CO. Combining thermostable mutations increases the stability of lambda repressor. Biochemistry. 1988 Sep 20; 27(19):7571-4.
      View in: PubMed
    23. Sauer RT, Hehir K, Stearman RS, Weiss MA, Jeitler-Nilsson A, Suchanek EG, Pabo CO. An engineered intersubunit disulfide enhances the stability and DNA binding of the N-terminal domain of lambda repressor. Biochemistry. 1986 Oct 7; 25(20):5992-8.
      View in: PubMed
    24. Lowell CA, Stearman RS, Morrow JF. Transcriptional regulation of serum amyloid A gene expression. J Biol Chem. 1986 Jun 25; 261(18):8453-61.
      View in: PubMed
    25. Lowell CA, Potter DA, Stearman RS, Morrow JF. Structure of the murine serum amyloid A gene family. Gene conversion. J Biol Chem. 1986 Jun 25; 261(18):8442-52.
      View in: PubMed
    26. Stearman RS, Lowell CA, Peltzman CG, Morrow JF. The sequence and structure of a new serum amyloid A gene. Nucleic Acids Res. 1986 Jan 24; 14(2):797-809.
      View in: PubMed
    27. Weiss MA, Stearman R, Jeitler-Nilsson A, Karplus M, Sauer RT. Protein-Protein Interactions in DNA Recognition: H-NMR Studies of Lambda cI Repressors Genetically Altered by Site-Directed Mutagenesis. Biophys J. 1986 Jan; 49(1):29-33.
      View in: PubMed
    28. Stearman RS, Lowell CA, Pearson WR, Morrow JF. Regulation of synthesis of amyloid A-related protein. Ann N Y Acad Sci. 1982; 389:106-15.
      View in: PubMed
    29. Morrow JF, Stearman RS, Peltzman CG, Potter DA. Induction of hepatic synthesis of serum amyloid A protein and actin. Proc Natl Acad Sci U S A. 1981 Aug; 78(8):4718-22.
      View in: PubMed
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