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Pepper Schedin

TitleProfessor Adjoint
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-MED

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    R29CA070915     (SCHEDIN, PEPPER J)Jun 1, 1996 - May 31, 2001
    NIH/NCI
    ECM MEDIATORS OF CHEMOPREVENTIVE AGENTS IN THE BREAST
    Role: Principal Investigator
    R01CA085944     (SCHEDIN, PEPPER J)Jun 4, 2001 - May 31, 2006
    NIH/NCI
    Endocrine Status of MG Stroma Alters Breast CA Invasion
    Role: Principal Investigator
    R01CA164166     (MACLEAN, PAUL S.)Feb 1, 2013 - Jan 31, 2018
    NIH/NCI
    A Narrowed Window for Targeting Metabolic Flexibility in Breast Cancer Prevention
    Role: Co-Principal Investigator
    R01CA169175     (SCHEDIN, PEPPER J)Apr 1, 2013 - Mar 31, 2018
    NIH/NCI
    NSAIDs During Postpartum Involution for Breast Cancer Chemoprevention
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Goddard ET, Bassale S, Schedin T, Jindal S, Johnston J, Cabral E, Latour E, Lyons TR, Mori M, Schedin PJ, Borges VF. Association Between Postpartum Breast Cancer Diagnosis and Metastasis and the Clinical Features Underlying Risk. JAMA Netw Open. 2019 Jan 04; 2(1):e186997. PMID: 30646210.
      View in: PubMed
    2. Pennock ND, Martinson HA, Guo Q, Betts CB, Jindal S, Tsujikawa T, Coussens LM, Borges VF, Schedin P. Ibuprofen supports macrophage differentiation, T cell recruitment, and tumor suppression in a model of postpartum breast cancer. J Immunother Cancer. 2018 Oct 01; 6(1):98. PMID: 30285905.
      View in: PubMed
    3. Elder AM, Tamburini BAJ, Crump LS, Black SA, Wessells VM, Schedin PJ, Borges VF, Lyons TR. Semaphorin 7A Promotes Macrophage-Mediated Lymphatic Remodeling during Postpartum Mammary Gland Involution and in Breast Cancer. Cancer Res. 2018 Nov 15; 78(22):6473-6485. PMID: 30254150.
      View in: PubMed
    4. Giles ED, Jindal S, Wellberg EA, Schedin T, Anderson SM, Thor AD, Edwards DP, MacLean PS, Schedin P. Metformin inhibits stromal aromatase expression and tumor progression in a rodent model of postmenopausal breast cancer. Breast Cancer Res. 2018 06 14; 20(1):50. PMID: 29898754.
      View in: PubMed
    5. Betts CB, Pennock ND, Caruso BP, Ruffell B, Borges VF, Schedin P. Mucosal Immunity in the Female Murine Mammary Gland. J Immunol. 2018 Jul 15; 201(2):734-746. PMID: 29884705.
      View in: PubMed
    6. Gray E, Mitchell E, Jindal S, Schedin P, Chang YH. A METHOD FOR QUANTIFICATION OF CALPONIN EXPRESSION IN MYOEPITHELIAL CELLS IN IMMUNOHISTOCHEMICAL IMAGES OF DUCTAL CARCINOMA IN SITU. Proc IEEE Int Symp Biomed Imaging. 2018 Apr; 2018:796-799. PMID: 30364524.
      View in: PubMed
    7. Minnier J, Pennock ND, Guo Q, Schedin P, Harrington CA. Erratum to: RNA-Seq and Expression Arrays: Selection Guidelines for Genome-Wide Expression Profiling. Methods Mol Biol. 2018; 1783:E1. PMID: 29992527.
      View in: PubMed
    8. Minnier J, Pennock ND, Guo Q, Schedin P, Harrington CA. RNA-Seq and Expression Arrays: Selection Guidelines for Genome-Wide Expression Profiling. Methods Mol Biol. 2018; 1783:7-33. PMID: 29767356.
      View in: PubMed
    9. Wellberg EA, Checkley LA, Giles ED, Johnson SJ, Oljira R, Wahdan-Alaswad R, Foright RM, Dooley G, Edgerton SM, Jindal S, Johnson GC, Richer JK, Kabos P, Thor AD, Schedin P, MacLean PS, Anderson SM. The Androgen Receptor Supports Tumor Progression After the Loss of Ovarian Function in a Preclinical Model of Obesity and Breast Cancer. Horm Cancer. 2017 12; 8(5-6):269-285. PMID: 28741260.
      View in: PubMed
    10. Guo Q, Minnier J, Burchard J, Chiotti K, Spellman P, Schedin P. Physiologically activated mammary fibroblasts promote postpartum mammary cancer. JCI Insight. 2017 Mar 23; 2(6):e89206. PMID: 28352652.
      View in: PubMed
    11. Checkley LA, Rudolph MC, Wellberg EA, Giles ED, Wahdan-Alaswad RS, Houck JA, Edgerton SM, Thor AD, Schedin P, Anderson SM, MacLean PS. Metformin Accumulation Correlates with Organic Cation Transporter 2 Protein Expression and Predicts Mammary Tumor Regression In Vivo. Cancer Prev Res (Phila). 2017 Mar; 10(3):198-207. PMID: 28154203.
      View in: PubMed
    12. Guo Q, Betts C, Pennock N, Mitchell E, Schedin P. Mammary Gland Involution Provides a Unique Model to Study the TGF-ß Cancer Paradox. J Clin Med. 2017 Jan 13; 6(1). PMID: 28098775.
      View in: PubMed
    13. Bruno RD, Fleming JM, George AL, Boulanger CA, Schedin P, Smith GH. Mammary extracellular matrix directs differentiation of testicular and embryonic stem cells to form functional mammary glands in vivo. Sci Rep. 2017 01 10; 7:40196. PMID: 28071703.
      View in: PubMed
    14. Goddard ET, Fischer J, Schedin P. A Portal Vein Injection Model to Study Liver Metastasis of Breast Cancer. J Vis Exp. 2016 12 26; (118). PMID: 28060292.
      View in: PubMed
    15. Goddard ET, Hill RC, Nemkov T, D'Alessandro A, Hansen KC, Maller O, Mongoue-Tchokote S, Mori M, Partridge AH, Borges VF, Schedin P. The Rodent Liver Undergoes Weaning-Induced Involution and Supports Breast Cancer Metastasis. Cancer Discov. 2017 02; 7(2):177-187. PMID: 27974414.
      View in: PubMed
    16. Goddard ET, Hill RC, Barrett A, Betts C, Guo Q, Maller O, Borges VF, Hansen KC, Schedin P. Quantitative extracellular matrix proteomics to study mammary and liver tissue microenvironments. Int J Biochem Cell Biol. 2016 12; 81(Pt A):223-232. PMID: 27771439.
      View in: PubMed
    17. Wang Y, Jindal S, Martel M, Wu Y, Schedin P, Troxell M. Myoepithelial cells in lobular carcinoma in situ: distribution and immunophenotype. Hum Pathol. 2016 09; 55:126-34. PMID: 27195907.
      View in: PubMed
    18. Esbona K, Inman D, Saha S, Jeffery J, Schedin P, Wilke L, Keely P. COX-2 modulates mammary tumor progression in response to collagen density. Breast Cancer Res. 2016 Mar 22; 18(1):35. PMID: 27000374; PMCID: PMC4802888.
      View in: PubMed, PubMed Central
    19. Ruszczyk M, Zirpoli G, Kumar S, Bandera EV, Bovbjerg DH, Jandorf L, Khoury T, Hwang H, Ciupak G, Pawlish K, Schedin P, Masso-Welch P, Ambrosone CB, Hong CC. Breast cancer risk factor associations differ for pure versus invasive carcinoma with an in situ component in case-control and case-case analyses. Cancer Causes Control. 2016 Feb; 27(2):183-98. PMID: 26621543; PMCID: PMC4724280 [Available on 02/01/17].
      View in: PubMed, PubMed Central
    20. Russell TD, Jindal S, Agunbiade S, Gao D, Troxell M, Borges VF, Schedin P. Myoepithelial cell differentiation markers in ductal carcinoma in situ progression. Am J Pathol. 2015 Nov; 185(11):3076-89. PMID: 26343330; PMCID: PMC4630168 [Available on 11/01/16].
      View in: PubMed, PubMed Central
    21. Fornetti J, Flanders KC, Henson PM, Tan AC, Borges VF, Schedin P. Mammary epithelial cell phagocytosis downstream of TGF-ß3 is characterized by adherens junction reorganization. Cell Death Differ. 2016 Feb; 23(2):185-96. PMID: 26113040.
      View in: PubMed
    22. Ambrosone CB, Zirpoli G, Hong CC, Yao S, Troester MA, Bandera EV, Schedin P, Bethea TN, Borges V, Park SY, Chandra D, Rosenberg L, Kolonel LN, Olshan AF, Palmer JR. Important Role of Menarche in Development of Estrogen Receptor-Negative Breast Cancer in African American Women. J Natl Cancer Inst. 2015 Sep; 107(9). PMID: 26085483; PMCID: PMC4836800.
      View in: PubMed, PubMed Central
    23. Collins LC, Gelber S, Marotti JD, White S, Ruddy K, Brachtel EF, Schapira L, Come SE, Borges VF, Schedin P, Warner E, Wensley T, Tamimi RM, Winer EP, Partridge AH. Molecular Phenotype of Breast Cancer According to Time Since Last Pregnancy in a Large Cohort of Young Women. Oncologist. 2015 Jul; 20(7):713-8. PMID: 26025931; PMCID: PMC4492229.
      View in: PubMed, PubMed Central
    24. Morton JJ, Bird G, Keysar SB, Astling DP, Lyons TR, Anderson RT, Glogowska MJ, Estes P, Eagles JR, Le PN, Gan G, McGettigan B, Fernandez P, Padilla-Just N, Varella-Garcia M, Song JI, Bowles DW, Schedin P, Tan AC, Roop DR, Wang XJ, Refaeli Y, Jimeno A. XactMice: humanizing mouse bone marrow enables microenvironment reconstitution in a patient-derived xenograft model of head and neck cancer. Oncogene. 2016 Jan 21; 35(3):290-300. PMID: 25893296; PMCID: PMC4613815.
      View in: PubMed, PubMed Central
    25. Bethea TN, Rosenberg L, Hong CC, Troester MA, Lunetta KL, Bandera EV, Schedin P, Kolonel LN, Olshan AF, Ambrosone CB, Palmer JR. A case-control analysis of oral contraceptive use and breast cancer subtypes in the African American Breast Cancer Epidemiology and Risk Consortium. Breast Cancer Res. 2015 Feb 21; 17:22. PMID: 25849024; PMCID: PMC4358874.
      View in: PubMed, PubMed Central
    26. Tung JC, Barnes JM, Desai SR, Sistrunk C, Conklin MW, Schedin P, Eliceiri KW, Keely PJ, Seewaldt VL, Weaver VM. Tumor mechanics and metabolic dysfunction. Free Radic Biol Med. 2015 Feb; 79:269-80. PMID: 25532934.
      View in: PubMed
    27. Palmer JR, Viscidi E, Troester MA, Hong CC, Schedin P, Bethea TN, Bandera EV, Borges V, McKinnon C, Haiman CA, Lunetta K, Kolonel LN, Rosenberg L, Olshan AF, Ambrosone CB. Parity, lactation, and breast cancer subtypes in African American women: results from the AMBER Consortium. J Natl Cancer Inst. 2014 Oct; 106(10). PMID: 25224496; PMCID: PMC4271113.
      View in: PubMed, PubMed Central
    28. Martinson HA, Jindal S, Durand-Rougely C, Borges VF, Schedin P. Wound healing-like immune program facilitates postpartum mammary gland involution and tumor progression. Int J Cancer. 2015 Apr 15; 136(8):1803-13. PMID: 25187059; PMCID: PMC4324053.
      View in: PubMed, PubMed Central
    29. Lyons TR, Borges VF, Betts CB, Guo Q, Kapoor P, Martinson HA, Jindal S, Schedin P. Cyclooxygenase-2-dependent lymphangiogenesis promotes nodal metastasis of postpartum breast cancer. J Clin Invest. 2014 Sep; 124(9):3901-12. PMID: 25133426; PMCID: PMC4153700.
      View in: PubMed, PubMed Central
    30. Fornetti J, Martinson HA, Betts CB, Lyons TR, Jindal S, Guo Q, Coussens LM, Borges VF, Schedin P. Mammary gland involution as an immunotherapeutic target for postpartum breast cancer. J Mammary Gland Biol Neoplasia. 2014 Jul; 19(2):213-28. PMID: 24952477.
      View in: PubMed
    31. Jindal S, Gao D, Bell P, Albrektsen G, Edgerton SM, Ambrosone CB, Thor AD, Borges VF, Schedin P. Postpartum breast involution reveals regression of secretory lobules mediated by tissue-remodeling. Breast Cancer Res. 2014 Mar 28; 16(2):R31. PMID: 24678808; PMCID: PMC4053254.
      View in: PubMed, PubMed Central
    32. Fornetti J, Jindal S, Middleton KA, Borges VF, Schedin P. Physiological COX-2 expression in breast epithelium associates with COX-2 levels in ductal carcinoma in situ and invasive breast cancer in young women. Am J Pathol. 2014 Apr; 184(4):1219-1229. PMID: 24518566.
      View in: PubMed
    33. Haricharan S, Dong J, Hein S, Reddy JP, Du Z, Toneff M, Holloway K, Hilsenbeck SG, Huang S, Atkinson R, Woodward W, Jindal S, Borges VF, Gutierrez C, Zhang H, Schedin PJ, Osborne CK, Tweardy DJ, Li Y. Mechanism and preclinical prevention of increased breast cancer risk caused by pregnancy. Elife. 2013 Dec 31; 2:e00996. PMID: 24381245; PMCID: PMC3874103.
      View in: PubMed, PubMed Central
    34. Jacob A, Jing J, Lee J, Schedin P, Gilbert SM, Peden AA, Junutula JR, Prekeris R. Rab40b regulates trafficking of MMP2 and MMP9 during invadopodia formation and invasion of breast cancer cells. J Cell Sci. 2013 Oct 15; 126(Pt 20):4647-58. PMID: 23902685; PMCID: PMC3795337.
      View in: PubMed, PubMed Central
    35. Maller O, Hansen KC, Lyons TR, Acerbi I, Weaver VM, Prekeris R, Tan AC, Schedin P. Collagen architecture in pregnancy-induced protection from breast cancer. J Cell Sci. 2013 Sep 15; 126(Pt 18):4108-10. PMID: 23843613; PMCID: PMC3772386.
      View in: PubMed, PubMed Central
    36. Martinson HA, Lyons TR, Giles ED, Borges VF, Schedin P. Developmental windows of breast cancer risk provide opportunities for targeted chemoprevention. Exp Cell Res. 2013 Jul 01; 319(11):1671-8. PMID: 23664839; PMCID: PMC3980135.
      View in: PubMed, PubMed Central
    37. Harvell DM, Kim J, O'Brien J, Tan AC, Borges VF, Schedin P, Jacobsen BM, Horwitz KB. Genomic signatures of pregnancy-associated breast cancer epithelia and stroma and their regulation by estrogens and progesterone. Horm Cancer. 2013 Jun; 4(3):140-53. PMID: 23479404; PMCID: PMC3810166.
      View in: PubMed, PubMed Central
    38. Callihan EB, Gao D, Jindal S, Lyons TR, Manthey E, Edgerton S, Urquhart A, Schedin P, Borges VF. Postpartum diagnosis demonstrates a high risk for metastasis and merits an expanded definition of pregnancy-associated breast cancer. Breast Cancer Res Treat. 2013 Apr; 138(2):549-59. PMID: 23430224; PMCID: PMC3608871.
      View in: PubMed, PubMed Central
    39. Faupel-Badger JM, Arcaro KF, Balkam JJ, Eliassen AH, Hassiotou F, Lebrilla CB, Michels KB, Palmer JR, Schedin P, Stuebe AM, Watson CJ, Sherman ME. Postpartum remodeling, lactation, and breast cancer risk: summary of a National Cancer Institute-sponsored workshop. J Natl Cancer Inst. 2013 Feb 06; 105(3):166-74. PMID: 23264680; PMCID: PMC3611853.
      View in: PubMed, PubMed Central
    40. Cruz GI, Martínez ME, Natarajan L, Wertheim BC, Gago-Dominguez M, Bondy M, Daneri-Navarro A, Meza-Montenegro MM, Gutierrez-Millan LE, Brewster A, Schedin P, Komenaka IK, Castelao JE, Carracedo A, Redondo CM, Thompson PA. Hypothesized role of pregnancy hormones on HER2+ breast tumor development. Breast Cancer Res Treat. 2013 Jan; 137(1):237-46. PMID: 23135573; PMCID: PMC4054812.
      View in: PubMed, PubMed Central
    41. O'Brien JH, Vanderlinden LA, Schedin PJ, Hansen KC. Rat mammary extracellular matrix composition and response to ibuprofen treatment during postpartum involution by differential GeLC-MS/MS analysis. J Proteome Res. 2012 Oct 05; 11(10):4894-905. PMID: 22897585; PMCID: PMC4292908.
      View in: PubMed, PubMed Central
    42. Ramirez RA, Lee A, Schedin P, Russell JS, Masso-Welch PA. Alterations in mast cell frequency and relationship to angiogenesis in the rat mammary gland during windows of physiologic tissue remodeling. Dev Dyn. 2012 May; 241(5):890-900. PMID: 22431477.
      View in: PubMed
    43. Fornetti J, Martinson H, Borges V, Schedin P. Emerging targets for the prevention of pregnancy-associated breast cancer. Cell Cycle. 2012 Feb 15; 11(4):639-40. PMID: 22374663.
      View in: PubMed
    44. O'Brien J, Martinson H, Durand-Rougely C, Schedin P. Macrophages are crucial for epithelial cell death and adipocyte repopulation during mammary gland involution. Development. 2012 Jan; 139(2):269-75. PMID: 22129827.
      View in: PubMed
    45. Borges VF, Schedin PJ. Pregnancy-associated breast cancer: an entity needing refinement of the definition. Cancer. 2012 Jul 01; 118(13):3226-8. PMID: 22086839; PMCID: PMC3979933.
      View in: PubMed, PubMed Central
    46. Lyons TR, O'Brien J, Borges VF, Conklin MW, Keely PJ, Eliceiri KW, Marusyk A, Tan AC, Schedin P. Postpartum mammary gland involution drives progression of ductal carcinoma in situ through collagen and COX-2. Nat Med. 2011 Aug 07; 17(9):1109-15. PMID: 21822285; PMCID: PMC3888478.
      View in: PubMed, PubMed Central
    47. Schedin P, Keely PJ. Mammary gland ECM remodeling, stiffness, and mechanosignaling in normal development and tumor progression. Cold Spring Harb Perspect Biol. 2011 Jan 01; 3(1):a003228. PMID: 20980442; PMCID: PMC3003460.
      View in: PubMed, PubMed Central
    48. O'Brien J, Hansen K, Barkan D, Green J, Schedin P, O'Brien J, Hansen K, Barkan D, Green J, Schedin P. Non-steroidal anti-inflammatory drugs target the pro-tumorigenic extracellular matrix of the postpartum mammary gland. Int J Dev Biol. 2011; 55(7-9):745-55. PMID: 22161831.
      View in: PubMed
    49. Giles ED, Jackman MR, Johnson GC, Schedin PJ, Houser JL, MacLean PS. Effect of the estrous cycle and surgical ovariectomy on energy balance, fuel utilization, and physical activity in lean and obese female rats. Am J Physiol Regul Integr Comp Physiol. 2010 Dec; 299(6):R1634-42. PMID: 20926768; PMCID: PMC3007190.
      View in: PubMed, PubMed Central
    50. Schedin P, Hovey RC. Editorial: The mammary stroma in normal development and function. J Mammary Gland Biol Neoplasia. 2010 Sep; 15(3):275-7. PMID: 20824491; PMCID: PMC2941044.
      View in: PubMed, PubMed Central
    51. Maller O, Martinson H, Schedin P. Extracellular matrix composition reveals complex and dynamic stromal-epithelial interactions in the mammary gland. J Mammary Gland Biol Neoplasia. 2010 Sep; 15(3):301-18. PMID: 20811805.
      View in: PubMed
    52. O'Brien J, Fornetti J, Schedin P. Isolation of mammary-specific extracellular matrix to assess acute cell-ECM interactions in 3D culture. J Mammary Gland Biol Neoplasia. 2010 Sep; 15(3):353-64. PMID: 20680416.
      View in: PubMed
    53. Poczobutt JM, Tentler J, Lu X, Schedin PJ, Gutierrez-Hartmann A. Benign mammary epithelial cells enhance the transformed phenotype of human breast cancer cells. BMC Cancer. 2010 Jul 16; 10:373. PMID: 20637104; PMCID: PMC2913961.
      View in: PubMed, PubMed Central
    54. O'Brien J, Lyons T, Monks J, Lucia MS, Wilson RS, Hines L, Man YG, Borges V, Schedin P. Alternatively activated macrophages and collagen remodeling characterize the postpartum involuting mammary gland across species. Am J Pathol. 2010 Mar; 176(3):1241-55. PMID: 20110414; PMCID: PMC2832146.
      View in: PubMed, PubMed Central
    55. Taraseviciute A, Vincent BT, Schedin P, Jones PL. Quantitative analysis of three-dimensional human mammary epithelial tissue architecture reveals a role for tenascin-C in regulating c-met function. Am J Pathol. 2010 Feb; 176(2):827-38. PMID: 20042668; PMCID: PMC2808088.
      View in: PubMed, PubMed Central
    56. MacLean PS, Giles ED, Johnson GC, McDaniel SM, Fleming-Elder BK, Gilman KA, Andrianakos AG, Jackman MR, Shroyer KR, Schedin PJ. A surprising link between the energetics of ovariectomy-induced weight gain and mammary tumor progression in obese rats. Obesity (Silver Spring). 2010 Apr; 18(4):696-703. PMID: 19798068; PMCID: PMC4973619.
      View in: PubMed, PubMed Central
    57. Schedin PJ, Watson CJ. The complexity of the relationships between age at first birth and breast cancer incidence curves implicate pregnancy in cancer initiation as well as promotion of existing lesions. Preface. J Mammary Gland Biol Neoplasia. 2009 Jun; 14(2):85-6. PMID: 19437108.
      View in: PubMed
    58. Lyons TR, Schedin PJ, Borges VF. Pregnancy and breast cancer: when they collide. J Mammary Gland Biol Neoplasia. 2009 Jun; 14(2):87-98. PMID: 19381788; PMCID: PMC2693784.
      View in: PubMed, PubMed Central
    59. O'Brien J, Schedin P. Macrophages in breast cancer: do involution macrophages account for the poor prognosis of pregnancy-associated breast cancer? J Mammary Gland Biol Neoplasia. 2009 Jun; 14(2):145-57. PMID: 19350209; PMCID: PMC2693782.
      View in: PubMed, PubMed Central
    60. Hansen KC, Kiemele L, Maller O, O'Brien J, Shankar A, Fornetti J, Schedin P. An in-solution ultrasonication-assisted digestion method for improved extracellular matrix proteome coverage. Mol Cell Proteomics. 2009 Jul; 8(7):1648-57. PMID: 19351662.
      View in: PubMed
    61. Billups SC, Neville MC, Rudolph M, Porter W, Schedin P. Identifying significant temporal variation in time course microarray data without replicates. BMC Bioinformatics. 2009 Mar 26; 10:96. PMID: 19323838; PMCID: PMC2682797.
      View in: PubMed, PubMed Central
    62. Schedin P, Borges V. Breaking down barriers: the importance of the stromal microenvironment in acquiring invasiveness in young women's breast cancer. Breast Cancer Res. 2009; 11(2):102. PMID: 19344495; PMCID: PMC2688940.
      View in: PubMed, PubMed Central
    63. Hattar R, Maller O, McDaniel S, Hansen KC, Hedman KJ, Lyons TR, Lucia S, Wilson RS, Schedin P. Tamoxifen induces pleiotrophic changes in mammary stroma resulting in extracellular matrix that suppresses transformed phenotypes. Breast Cancer Res. 2009; 11(1):R5. PMID: 19173736; PMCID: PMC2687708.
      View in: PubMed, PubMed Central
    64. Laffin B, Wellberg E, Kwak HI, Burghardt RC, Metz RP, Gustafson T, Schedin P, Porter WW. Loss of singleminded-2s in the mouse mammary gland induces an epithelial-mesenchymal transition associated with up-regulation of slug and matrix metalloprotease 2. Mol Cell Biol. 2008 Mar; 28(6):1936-46. PMID: 18160708; PMCID: PMC2268409.
      View in: PubMed, PubMed Central
    65. McDaniel SM, O'Neill C, Metz RP, Tarbutton E, Stacewicz-Sapuntzakis M, Heimendinger J, Wolfe P, Thompson H, Schedin P. Whole-food sources of vitamin A more effectively inhibit female rat sexual maturation, mammary gland development, and mammary carcinogenesis than retinyl palmitate. J Nutr. 2007 Jun; 137(6):1415-22. PMID: 17513400.
      View in: PubMed
    66. Schedin P, O'Brien J, Rudolph M, Stein T, Borges V. Microenvironment of the involuting mammary gland mediates mammary cancer progression. J Mammary Gland Biol Neoplasia. 2007 Mar; 12(1):71-82. PMID: 17318269.
      View in: PubMed
    67. Kwak HI, Gustafson T, Metz RP, Laffin B, Schedin P, Porter WW. Inhibition of breast cancer growth and invasion by single-minded 2s. Carcinogenesis. 2007 Feb; 28(2):259-66. PMID: 16840439.
      View in: PubMed
    68. Schedin P. Pregnancy-associated breast cancer and metastasis. Nat Rev Cancer. 2006 Apr; 6(4):281-91. PMID: 16557280.
      View in: PubMed
    69. McDaniel SM, Rumer KK, Biroc SL, Metz RP, Singh M, Porter W, Schedin P. Remodeling of the mammary microenvironment after lactation promotes breast tumor cell metastasis. Am J Pathol. 2006 Feb; 168(2):608-20. PMID: 16436674; PMCID: PMC1606507.
      View in: PubMed, PubMed Central
    70. Schedin P, Mitrenga T, McDaniel S, Kaeck M. Mammary ECM composition and function are altered by reproductive state. Mol Carcinog. 2004 Dec; 41(4):207-20. PMID: 15468292.
      View in: PubMed
    71. Schedin PJ, Eckel-Mahan KL, McDaniel SM, Prescott JD, Brodsky KS, Tentler JJ, Gutierrez-Hartmann A. ESX induces transformation and functional epithelial to mesenchymal transition in MCF-12A mammary epithelial cells. Oncogene. 2004 Mar 04; 23(9):1766-79. PMID: 14767472.
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    72. Schedin P, Elias A. Multistep tumorigenesis and the microenvironment. Breast Cancer Res. 2004; 6(2):93-101. PMID: 14979914; PMCID: PMC400664.
      View in: PubMed, PubMed Central
    73. Bemis LT, Schedin P. Reproductive state of rat mammary gland stroma modulates human breast cancer cell migration and invasion. Cancer Res. 2000 Jul 01; 60(13):3414-8. PMID: 10910049.
      View in: PubMed
    74. Schedin P, Mitrenga T, Kaeck M. Estrous cycle regulation of mammary epithelial cell proliferation, differentiation, and death in the Sprague-Dawley rat: a model for investigating the role of estrous cycling in mammary carcinogenesis. J Mammary Gland Biol Neoplasia. 2000 Apr; 5(2):211-25. PMID: 11149574.
      View in: PubMed
    75. Schedin P, Strange R, Mitrenga T, Wolfe P, Kaeck M. Fibronectin fragments induce MMP activity in mouse mammary epithelial cells: evidence for a role in mammary tissue remodeling. J Cell Sci. 2000 Mar; 113 ( Pt 5):795-806. PMID: 10671369.
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    76. Schedin PJ, Byers T. Adolescent diet and the risk of breast cancer in adulthood: a role for vitamin A? Nutrition. 1997 Oct; 13(10):924-5. PMID: 9357037.
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    77. Schedin PJ, Thackray LB, Malone P, Fontaine SC, Friis RR, Strange R. Programmed cell death and mammary neoplasia. Cancer Treat Res. 1996; 83:3-22. PMID: 8826639.
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    78. Schedin PJ, Strange R, Singh M, Kaeck MR, Fontaine SC, Thompson HJ. Treatment with chemopreventive agents, difluoromethylornithine and retinyl acetate, results in altered mammary extracellular matrix. Carcinogenesis. 1995 Aug; 16(8):1787-94. PMID: 7634405.
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    79. Schedin P, Jonas P, Wood WB. Function of the her-1 gene is required for maintenance of male differentiation in adult tissues of C. elegans. Dev Genet. 1994; 15(3):231-9. PMID: 8062456.
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    80. Thompson HJ, Strange R, Schedin PJ. Apoptosis in the genesis and prevention of cancer. Cancer Epidemiol Biomarkers Prev. 1992 Nov-Dec; 1(7):597-602. PMID: 1302573.
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    81. Wilson AC, Thompson HJ, Schedin PJ, Gibson NW, Ganther HE. Effect of methylated forms of selenium on cell viability and the induction of DNA strand breakage. Biochem Pharmacol. 1992 Mar 03; 43(5):1137-41. PMID: 1554385.
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    82. Schedin P, Hunter CP, Wood WB. Autonomy and nonautonomy of sex determination in triploid intersex mosaics of C. elegans. Development. 1991 Jul; 112(3):863-79. PMID: 1935692.
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    83. Wood WB, Meneely P, Schedin P, Donahue L. Aspects of dosage compensation and sex determination in Caenorhabditis elegans. Cold Spring Harb Symp Quant Biol. 1985; 50:575-83. PMID: 3868495.
      View in: PubMed
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