Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Todd Pitts

Concepts (373)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Colorectal Neoplasms
22
2022
620
2.980
Why?
Protein Kinase Inhibitors
19
2020
788
2.030
Why?
Xenograft Model Antitumor Assays
37
2022
716
2.000
Why?
Antineoplastic Agents
25
2020
1890
1.580
Why?
Azepines
4
2020
67
1.450
Why?
Pyrimidines
9
2020
377
1.300
Why?
Pyrazines
6
2018
70
1.110
Why?
Cell Line, Tumor
33
2022
2756
1.040
Why?
Mice, Nude
24
2020
641
1.020
Why?
Cell Proliferation
21
2020
2197
0.900
Why?
Fluorouracil
1
2022
149
0.810
Why?
Triple Negative Breast Neoplasms
6
2020
157
0.800
Why?
Camptothecin
5
2022
98
0.680
Why?
Apoptosis
20
2022
2363
0.670
Why?
Imidazoles
4
2018
209
0.670
Why?
Aurora Kinase A
4
2020
50
0.670
Why?
Proto-Oncogene Proteins
5
2018
604
0.670
Why?
Drug Resistance, Neoplasm
11
2020
646
0.610
Why?
Drug Synergism
4
2014
314
0.600
Why?
Neoplasms
9
2022
2110
0.580
Why?
Cell Cycle Proteins
2
2018
559
0.530
Why?
Cell Cycle Checkpoints
3
2019
84
0.520
Why?
Hydroxamic Acids
3
2011
80
0.520
Why?
Antineoplastic Combined Chemotherapy Protocols
9
2020
1359
0.510
Why?
Tumor Microenvironment
5
2022
440
0.500
Why?
Histone Deacetylase Inhibitors
4
2022
199
0.500
Why?
Receptor, IGF Type 1
3
2013
58
0.500
Why?
Mice
38
2022
15075
0.490
Why?
Pyrazoles
5
2018
361
0.490
Why?
Disease Models, Animal
10
2022
3565
0.480
Why?
Adrenocortical Carcinoma
3
2020
47
0.480
Why?
Mitogen-Activated Protein Kinases
3
2014
269
0.470
Why?
Antimitotic Agents
1
2013
8
0.470
Why?
Benzimidazoles
5
2018
135
0.460
Why?
Pancreatic Neoplasms
5
2020
716
0.440
Why?
G2 Phase Cell Cycle Checkpoints
4
2022
41
0.440
Why?
TOR Serine-Threonine Kinases
2
2018
358
0.440
Why?
Cyclin-Dependent Kinases
1
2013
111
0.430
Why?
Boronic Acids
2
2011
33
0.420
Why?
Animals
42
2022
32091
0.420
Why?
Molecular Targeted Therapy
2
2019
351
0.410
Why?
Quinoxalines
4
2020
61
0.400
Why?
Colonic Neoplasms
2
2013
221
0.370
Why?
Biomarkers, Tumor
6
2018
1045
0.370
Why?
Drug Screening Assays, Antitumor
5
2020
180
0.360
Why?
Melanoma
4
2018
653
0.360
Why?
Signal Transduction
17
2019
4537
0.360
Why?
Heterografts
3
2021
121
0.360
Why?
Oxidoreductases Acting on CH-CH Group Donors
2
2020
20
0.340
Why?
Gene Expression Regulation, Neoplastic
9
2020
1142
0.330
Why?
Wnt Signaling Pathway
4
2020
149
0.320
Why?
Adrenal Cortex Neoplasms
2
2020
48
0.320
Why?
Gene Expression Profiling
6
2016
1567
0.310
Why?
Cell Cycle
7
2018
541
0.310
Why?
Enzyme Inhibitors
5
2020
749
0.300
Why?
Ephrin-B2
2
2019
42
0.300
Why?
Piperazines
2
2020
314
0.300
Why?
Programmed Cell Death 1 Receptor
2
2020
195
0.300
Why?
Deoxycytidine
2
2020
136
0.300
Why?
Humans
60
2022
115297
0.300
Why?
Drug Delivery Systems
1
2010
301
0.290
Why?
Tumor Suppressor Protein p53
4
2016
442
0.290
Why?
Quinazolines
3
2015
241
0.290
Why?
Phosphatidylinositol 3-Kinases
5
2018
329
0.280
Why?
Anilides
2
2018
67
0.270
Why?
Oncogene Proteins, Fusion
2
2018
177
0.270
Why?
Mitogen-Activated Protein Kinase Kinases
3
2019
113
0.270
Why?
Mutation
9
2018
3371
0.270
Why?
Female
38
2020
59773
0.270
Why?
Gene Dosage
4
2015
127
0.260
Why?
Cyclosporine
2
2018
169
0.260
Why?
Lymphocytes, Tumor-Infiltrating
3
2020
110
0.260
Why?
Immunoblotting
6
2015
284
0.250
Why?
Pyrimidinones
2
2015
86
0.240
Why?
Proto-Oncogene Proteins B-raf
3
2018
191
0.240
Why?
Proto-Oncogene Proteins p21(ras)
6
2016
229
0.240
Why?
Pyridones
2
2015
122
0.240
Why?
ras Proteins
4
2013
137
0.230
Why?
Receptor, Notch1
2
2015
59
0.230
Why?
Neoplasm Transplantation
4
2018
235
0.230
Why?
Pyridines
2
2018
417
0.220
Why?
Immunotherapy
3
2022
489
0.220
Why?
Antineoplastic Agents, Immunological
3
2020
158
0.220
Why?
HCT116 Cells
3
2018
69
0.210
Why?
Ataxia Telangiectasia Mutated Proteins
1
2022
61
0.210
Why?
Drug Design
2
2013
155
0.200
Why?
beta Catenin
2
2020
221
0.200
Why?
Gene Knockdown Techniques
4
2020
303
0.190
Why?
DNA-Binding Proteins
2
2020
1308
0.190
Why?
Momordica charantia
1
2020
14
0.180
Why?
Benzoxazoles
1
2020
16
0.180
Why?
HT29 Cells
2
2018
37
0.180
Why?
Neoplasms, Experimental
2
2019
153
0.180
Why?
eIF-2 Kinase
1
2019
24
0.170
Why?
Immune System
1
2021
174
0.170
Why?
src-Family Kinases
2
2017
88
0.170
Why?
DNA Helicases
1
2020
131
0.170
Why?
Inhibitory Concentration 50
2
2016
78
0.170
Why?
Tumor Burden
2
2018
267
0.160
Why?
Receptor, EphB4
1
2019
29
0.160
Why?
Plant Extracts
1
2020
153
0.160
Why?
Breast Neoplasms, Male
1
2018
28
0.160
Why?
Coenzymes
1
2018
16
0.160
Why?
4-Aminobenzoic Acid
1
2018
6
0.160
Why?
Thermodynamics
1
2020
378
0.160
Why?
MAP Kinase Kinase Kinases
2
2015
67
0.160
Why?
Neoplasm Invasiveness
3
2020
446
0.160
Why?
Septins
1
2018
40
0.150
Why?
Oncogene Proteins v-abl
1
2017
4
0.150
Why?
Adrenal Cortex
1
2018
32
0.150
Why?
Carcinoma, Pancreatic Ductal
1
2020
210
0.150
Why?
Dasatinib
1
2017
45
0.150
Why?
Colorectal Neoplasms, Hereditary Nonpolyposis
1
2018
31
0.150
Why?
Angiogenesis Inhibitors
3
2018
213
0.140
Why?
Neoplasm Proteins
1
2020
387
0.140
Why?
Vascular Endothelial Growth Factor Receptor-2
2
2014
86
0.140
Why?
Ubiquitin-Activating Enzymes
1
2016
13
0.140
Why?
Cyclopentanes
1
2016
15
0.140
Why?
Corynebacterium
1
2017
36
0.140
Why?
Tumor Cells, Cultured
4
2020
840
0.140
Why?
Transplantation, Heterologous
4
2022
187
0.140
Why?
Corynebacterium Infections
1
2017
31
0.140
Why?
Insulin-Like Growth Factor I
1
2018
285
0.140
Why?
Tankyrases
1
2016
12
0.140
Why?
Autophagy
1
2018
236
0.130
Why?
Cyclin-Dependent Kinase Inhibitor p21
1
2016
107
0.130
Why?
Cetuximab
1
2016
96
0.130
Why?
Biliary Tract Neoplasms
1
2015
20
0.130
Why?
Capecitabine
1
2015
46
0.130
Why?
Amyloid Precursor Protein Secretases
2
2013
73
0.130
Why?
Adenocarcinoma
2
2020
790
0.130
Why?
Drug Discovery
1
2016
124
0.130
Why?
Genes, ras
2
2018
91
0.130
Why?
Antibodies, Monoclonal, Humanized
1
2020
663
0.130
Why?
Cell Survival
3
2019
1011
0.130
Why?
Diphenylamine
1
2014
6
0.130
Why?
Germ-Line Mutation
2
2018
132
0.120
Why?
DNA Copy Number Variations
1
2015
156
0.120
Why?
Piperidines
1
2015
164
0.120
Why?
Proto-Oncogene Proteins c-met
1
2014
67
0.120
Why?
Benzamides
1
2014
170
0.120
Why?
Urinary Bladder Neoplasms
1
2016
198
0.120
Why?
Protein Kinases
1
2015
300
0.110
Why?
Up-Regulation
1
2016
818
0.110
Why?
Receptor, Insulin
1
2013
93
0.110
Why?
Tetrahydronaphthalenes
1
2013
29
0.110
Why?
Valine
1
2013
74
0.110
Why?
Mitosis
1
2013
167
0.110
Why?
Receptors, Notch
1
2013
84
0.110
Why?
Tumor Suppressor Proteins
1
2015
282
0.110
Why?
Bortezomib
2
2011
41
0.110
Why?
Computational Biology
1
2015
525
0.100
Why?
Middle Aged
12
2020
26936
0.100
Why?
Sirolimus
1
2013
191
0.100
Why?
Antineoplastic Agents, Phytogenic
1
2013
180
0.100
Why?
3' Untranslated Regions
1
2012
139
0.100
Why?
Head and Neck Neoplasms
1
2016
460
0.100
Why?
Benzodioxoles
1
2012
83
0.100
Why?
Proteasome Inhibitors
1
2011
40
0.100
Why?
Carcinoma, Squamous Cell
1
2016
596
0.100
Why?
Aldehyde Dehydrogenase
1
2012
130
0.100
Why?
Neoplasm Metastasis
3
2018
522
0.090
Why?
Nuclear Proteins
1
2015
591
0.090
Why?
Protease Inhibitors
1
2011
100
0.090
Why?
Phosphorylation
4
2019
1569
0.090
Why?
Mice, Inbred NOD
2
2022
559
0.090
Why?
Breast Neoplasms
2
2012
1858
0.090
Why?
Aged
9
2020
19253
0.090
Why?
Vascular Endothelial Growth Factor Receptor-3
1
2009
6
0.090
Why?
Mice, Inbred BALB C
3
2020
1164
0.080
Why?
Vascular Endothelial Growth Factor Receptor-1
1
2009
67
0.080
Why?
Carcinoma, Hepatocellular
1
2011
223
0.080
Why?
Gastrointestinal Neoplasms
1
2009
60
0.080
Why?
Class I Phosphatidylinositol 3-Kinases
3
2014
78
0.080
Why?
Cell Movement
2
2011
869
0.080
Why?
Immunosuppressive Agents
1
2013
663
0.080
Why?
Proto-Oncogene Proteins c-akt
3
2018
396
0.080
Why?
Positron-Emission Tomography
3
2018
292
0.080
Why?
Prognosis
4
2019
3337
0.080
Why?
Neutrophils
3
2019
1080
0.080
Why?
Feasibility Studies
1
2010
744
0.070
Why?
Farnesyltranstransferase
1
2007
20
0.070
Why?
Oligonucleotide Array Sequence Analysis
3
2015
757
0.070
Why?
Protein Conformation
2
2020
822
0.070
Why?
Adult
10
2018
30576
0.070
Why?
Reproducibility of Results
2
2010
2811
0.070
Why?
Maximum Tolerated Dose
2
2020
181
0.070
Why?
Gene Expression
2
2019
1451
0.070
Why?
Quinolones
1
2007
97
0.070
Why?
Male
12
2020
55796
0.070
Why?
Neovascularization, Pathologic
2
2018
281
0.060
Why?
Models, Molecular
2
2020
1388
0.060
Why?
Structure-Activity Relationship
2
2018
507
0.060
Why?
HMGB1 Protein
1
2003
46
0.050
Why?
Magnetic Resonance Spectroscopy
2
2018
482
0.050
Why?
Proto-Oncogene Proteins c-raf
1
2002
43
0.050
Why?
Adrenergic alpha-Agonists
1
2002
29
0.050
Why?
Adrenergic alpha-Antagonists
1
2002
30
0.050
Why?
Histones
2
2022
535
0.050
Why?
Neuroimmunomodulation
1
2002
69
0.050
Why?
Histone Deacetylase 1
1
2022
16
0.050
Why?
Aurora Kinases
2
2012
28
0.050
Why?
Adrenergic beta-Agonists
1
2002
127
0.050
Why?
Endotoxemia
1
2002
84
0.050
Why?
Flow Cytometry
2
2019
1045
0.050
Why?
Genetic Predisposition to Disease
1
2010
2202
0.050
Why?
Caspase 3
2
2013
234
0.050
Why?
Acetylation
1
2022
212
0.050
Why?
Chimerism
1
2021
28
0.050
Why?
Campylobacter jejuni
1
2000
11
0.050
Why?
Lymphoid Tissue
1
2021
63
0.050
Why?
Lymphocyte Subsets
1
2021
77
0.050
Why?
Cluster Analysis
2
2012
469
0.050
Why?
Catalase
1
2000
118
0.050
Why?
TCF Transcription Factors
1
2020
21
0.050
Why?
Adrenergic beta-Antagonists
1
2002
292
0.050
Why?
Mice, SCID
1
2021
321
0.050
Why?
Histone Deacetylases
1
2022
196
0.050
Why?
RNA, Neoplasm
1
2020
76
0.040
Why?
Antimetabolites, Antineoplastic
1
2020
82
0.040
Why?
Mechanistic Target of Rapamycin Complex 2
1
2020
57
0.040
Why?
Indolizines
1
2019
3
0.040
Why?
Forkhead Box Protein M1
1
2019
6
0.040
Why?
Mechanistic Target of Rapamycin Complex 1
1
2020
99
0.040
Why?
Myeloid Cell Leukemia Sequence 1 Protein
1
2019
22
0.040
Why?
Organoids
1
2020
75
0.040
Why?
Small Molecule Libraries
1
2020
81
0.040
Why?
MAP Kinase Kinase 2
2
2013
27
0.040
Why?
Crystallography, X-Ray
1
2020
408
0.040
Why?
MAP Kinase Kinase 1
2
2013
67
0.040
Why?
High-Throughput Screening Assays
1
2020
123
0.040
Why?
M Phase Cell Cycle Checkpoints
1
2018
23
0.040
Why?
Epithelial-Mesenchymal Transition
1
2020
169
0.040
Why?
Genetic Linkage
1
1999
311
0.040
Why?
Flavin-Adenine Dinucleotide
1
2018
14
0.040
Why?
NADP
1
2018
41
0.040
Why?
Hemorrhage
1
2002
598
0.040
Why?
Nausea
1
2018
102
0.040
Why?
Multifactorial Inheritance
1
1999
140
0.040
Why?
Carcinogenesis
1
2019
180
0.040
Why?
Aldosterone
1
2018
42
0.040
Why?
Radiotherapy
1
2019
185
0.040
Why?
Breast
1
2018
129
0.040
Why?
DNA Damage
1
2020
348
0.040
Why?
Kaplan-Meier Estimate
1
2020
825
0.040
Why?
Area Under Curve
1
2018
277
0.040
Why?
Drug Therapy, Combination
1
2020
958
0.040
Why?
Catalytic Domain
1
2018
202
0.040
Why?
Diarrhea
1
2018
173
0.040
Why?
RNA, Small Interfering
1
2019
546
0.040
Why?
Autistic Disorder
1
1999
163
0.040
Why?
Hypertension
2
2018
1063
0.040
Why?
Recombinant Proteins
1
2020
1241
0.040
Why?
Disease-Free Survival
1
2018
625
0.040
Why?
Fatigue
1
2018
293
0.030
Why?
RNA, Messenger
2
2020
2579
0.030
Why?
Ubiquitination
1
2016
86
0.030
Why?
Axin Protein
1
2016
17
0.030
Why?
Protein Isoforms
1
2017
337
0.030
Why?
Sequence Analysis, RNA
1
2018
396
0.030
Why?
T-Lymphocytes, Regulatory
1
2019
347
0.030
Why?
Administration, Oral
1
2018
735
0.030
Why?
Algorithms
2
2015
1488
0.030
Why?
Hematopoietic Stem Cell Transplantation
1
2021
519
0.030
Why?
Jagged-1 Protein
1
2015
22
0.030
Why?
Serrate-Jagged Proteins
1
2015
27
0.030
Why?
Tumor Protein p73
1
2015
15
0.030
Why?
Gene Duplication
1
2015
61
0.030
Why?
Binding Sites
1
2018
1187
0.030
Why?
Immunohistochemistry
1
2019
1634
0.030
Why?
Databases, Genetic
1
2015
199
0.030
Why?
Biopsy
1
2018
1053
0.030
Why?
Mice, Knockout
1
2021
2607
0.030
Why?
Treatment Outcome
3
2015
9127
0.030
Why?
Transcription, Genetic
1
2020
1311
0.030
Why?
Calcium-Binding Proteins
1
2015
205
0.030
Why?
Caspase 7
1
2013
22
0.030
Why?
CD8-Positive T-Lymphocytes
1
2019
687
0.030
Why?
Butadienes
1
2013
32
0.030
Why?
Cell Growth Processes
1
2013
51
0.030
Why?
Intercellular Signaling Peptides and Proteins
1
2015
347
0.030
Why?
Survival Analysis
1
2016
1218
0.030
Why?
Phenotype
1
2021
2854
0.030
Why?
Tumor Stem Cell Assay
1
2012
34
0.030
Why?
Everolimus
1
2013
63
0.030
Why?
Nitriles
1
2013
154
0.030
Why?
Random Allocation
1
2013
331
0.030
Why?
Neoplasm Staging
1
2015
1190
0.030
Why?
p38 Mitogen-Activated Protein Kinases
2
2003
252
0.030
Why?
Immunoprecipitation
1
2012
156
0.030
Why?
Calcium Signaling
1
2013
211
0.020
Why?
Cellular Senescence
1
2012
150
0.020
Why?
Disease Progression
1
2018
2423
0.020
Why?
Kinetics
1
2014
1549
0.020
Why?
PTEN Phosphohydrolase
1
2012
138
0.020
Why?
In Situ Hybridization, Fluorescence
1
2012
305
0.020
Why?
Enzyme Activation
2
2003
776
0.020
Why?
Proteasome Endopeptidase Complex
1
2011
137
0.020
Why?
Receptor, ErbB-2
1
2012
300
0.020
Why?
Li-Fraumeni Syndrome
1
2010
11
0.020
Why?
Neutropenia
1
2010
127
0.020
Why?
Nuclear Magnetic Resonance, Biomolecular
1
2011
237
0.020
Why?
Transcriptome
1
2015
745
0.020
Why?
Molecular Epidemiology
1
2010
69
0.020
Why?
Metabolome
1
2013
283
0.020
Why?
Population Groups
1
2010
58
0.020
Why?
Ki-67 Antigen
1
2010
104
0.020
Why?
Ligands
1
2011
561
0.020
Why?
Capillary Permeability
1
2010
134
0.020
Why?
Drug Combinations
1
2010
288
0.020
Why?
Australia
1
2010
207
0.020
Why?
Keratinocytes
1
2010
218
0.020
Why?
Membrane Proteins
1
2015
1032
0.020
Why?
NF-kappa B
2
2003
634
0.020
Why?
Antibodies, Monoclonal
1
2015
1259
0.020
Why?
Biomarkers
1
2019
3450
0.020
Why?
Sulfonamides
1
2011
446
0.020
Why?
Calcium
1
2013
1107
0.020
Why?
Enzyme-Linked Immunosorbent Assay
1
2009
783
0.020
Why?
Leukemia-Lymphoma, Adult T-Cell
1
2007
12
0.020
Why?
Reverse Transcriptase Polymerase Chain Reaction
1
2009
942
0.020
Why?
Verapamil
1
2007
32
0.020
Why?
Magnetic Resonance Imaging
1
2018
3070
0.020
Why?
Liver Neoplasms
1
2011
520
0.020
Why?
Blotting, Western
1
2009
1146
0.020
Why?
Clone Cells
1
2007
246
0.020
Why?
Calcium Channel Blockers
1
2007
114
0.020
Why?
Dose-Response Relationship, Drug
1
2010
1855
0.020
Why?
Family
1
2010
573
0.020
Why?
Metabolomics
1
2011
530
0.020
Why?
Cohort Studies
1
2015
4960
0.020
Why?
MicroRNAs
1
2012
615
0.020
Why?
Ovarian Neoplasms
1
2010
416
0.020
Why?
Adolescent
2
2018
17767
0.010
Why?
Phosphotransferases
1
2003
25
0.010
Why?
Young Adult
1
2018
10413
0.010
Why?
Phentolamine
1
2002
16
0.010
Why?
Ribosomal Protein S6 Kinases
1
2002
21
0.010
Why?
Brimonidine Tartrate
1
2002
9
0.010
Why?
Phenylephrine
1
2002
80
0.010
Why?
Propranolol
1
2002
53
0.010
Why?
Peroxidase
1
2002
145
0.010
Why?
Biological Transport
1
2003
375
0.010
Why?
Chemokines
1
2003
211
0.010
Why?
Mitogen-Activated Protein Kinase 3
1
2002
145
0.010
Why?
Cyclic AMP Response Element-Binding Protein
1
2002
127
0.010
Why?
Cyclic AMP-Dependent Protein Kinases
1
2002
136
0.010
Why?
Respiratory Burst
1
2000
15
0.010
Why?
omega-N-Methylarginine
1
2000
23
0.010
Why?
MAP Kinase Signaling System
1
2002
272
0.010
Why?
Inflammation Mediators
1
2003
475
0.010
Why?
Protein Processing, Post-Translational
1
2002
404
0.010
Why?
Statistical Distributions
1
1999
8
0.010
Why?
Matched-Pair Analysis
1
1999
35
0.010
Why?
Lipopolysaccharides
1
2003
822
0.010
Why?
Cloning, Molecular
1
2000
514
0.010
Why?
Intelligence Tests
1
1999
59
0.010
Why?
Chromosomes, Human
1
1999
40
0.010
Why?
Nuclear Family
1
1999
53
0.010
Why?
Hydrogen Peroxide
1
2000
286
0.010
Why?
Protein-Tyrosine Kinases
1
2002
399
0.010
Why?
Microsatellite Repeats
1
1999
141
0.010
Why?
Linkage Disequilibrium
1
1999
266
0.010
Why?
Models, Genetic
1
1999
583
0.010
Why?
Cells, Cultured
1
2003
3879
0.010
Why?
Cytokines
1
2003
1837
0.010
Why?
Cell Line
1
2000
2628
0.010
Why?
Molecular Sequence Data
1
1999
2773
0.010
Why?
Genotype
1
1999
1832
0.010
Why?
Sex Factors
1
1999
1734
0.010
Why?
Macrophages
1
2000
1273
0.010
Why?
Child, Preschool
1
1999
9124
0.000
Why?
Child
1
1999
18435
0.000
Why?
Pitts's Networks
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