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Timothy J Bernard

TitleAssociate Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus

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    K23HL096895     (BERNARD, TIMOTHY J)Sep 1, 2010 - Jun 30, 2015
    Investigation of Prognostic Factors in Childhood-Onset AIS: Role of Stroke Subtyp
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Ritchey Z, Mirsky DM, Weitzenkamp D, Bernard TJ, Herson PS, Stence NV. Age-associated hippocampal volume changes in childhood arterial ischemic stroke. Childs Nerv Syst. 2018 Dec 08. PMID: 30535770.
      View in: PubMed
    2. Fullerton HJ, Stence N, Hills NK, Jiang B, Amlie-Lefond C, Bernard TJ, Friedman NR, Ichord R, Mackay MT, Rafay MF, Chabrier S, Steinlin M, Elkind MSV, deVeber GA, Wintermark M. Focal Cerebral Arteriopathy of Childhood. Stroke. 2018 Nov; 49(11):2590-2596. PMID: 30355212.
      View in: PubMed
    3. Wintermark M, Hills NK, DeVeber GA, Barkovich AJ, Bernard TJ, Friedman NR, Mackay MT, Kirton A, Zhu G, Leiva-Salinas C, Hou Q, Fullerton HJ. Clinical and Imaging Characteristics of Arteriopathy Subtypes in Children with Arterial Ischemic Stroke: Results of the VIPS Study. AJNR Am J Neuroradiol. 2017 Nov; 38(11):2172-2179. PMID: 28982784.
      View in: PubMed
    4. Stence NV, Pabst LL, Hollatz AL, Mirsky DM, Herson PS, Poisson S, Traystman RJ, Bernard TJ. Predicting Progression of Intracranial Arteriopathies in Childhood Stroke With Vessel Wall Imaging. Stroke. 2017 08; 48(8):2274-2277. PMID: 28679853.
      View in: PubMed
    5. Freeman J, Deleyiannis F, Bernard TJ, Fenton LZ, Somme S, Wilkinson CC. Moyamoya in a Patient with Smith-Magenis Syndrome. Pediatr Neurosurg. 2017; 52(3):195-204. PMID: 28380489.
      View in: PubMed
    6. Felling RJ, Sun LR, Maxwell EC, Goldenberg N, Bernard T. Pediatric arterial ischemic stroke: Epidemiology, risk factors, and management. Blood Cells Mol Dis. 2017 09; 67:23-33. PMID: 28336156.
      View in: PubMed
    7. Rao S, Elkon B, Flett KB, Moss AF, Bernard TJ, Stroud B, Wilson KM. Long-Term Outcomes and Risk Factors Associated With Acute Encephalitis in Children. J Pediatric Infect Dis Soc. 2017 Mar 01; 6(1):20-27. PMID: 26553786.
      View in: PubMed
    8. Orfila JE, Grewal H, Dietz RM, Strnad F, Shimizu T, Moreno M, Schroeder C, Yonchek J, Rodgers KM, Dingman A, Bernard TJ, Quillinan N, Macklin WB, Traystman RJ, Herson PS. Delayed inhibition of tonic inhibition enhances functional recovery following experimental ischemic stroke. J Cereb Blood Flow Metab. 2017 Jan 01; 271678X17750761. PMID: 29283314.
      View in: PubMed
    9. Bernard TJ, Beslow LA, Manco-Johnson MJ, Armstrong-Wells J, Boada R, Weitzenkamp D, Hollatz A, Poisson S, Amlie-Lefond C, Lo W, deVeber G, Goldenberg NA, Dowling MM, Roach ES, Fullerton HJ, Benseler SM, Jordan LC, Kirton A, Ichord RN. Inter-Rater Reliability of the CASCADE Criteria: Challenges in Classifying Arteriopathies. Stroke. 2016 10; 47(10):2443-9. PMID: 27633024.
      View in: PubMed
    10. Rivkin MJ, Bernard TJ, Dowling MM, Amlie-Lefond C. Corrigendum to 'Guidelines for Urgent Management of Stroke in Children' [Pediatric Neurology 56 (2016) 8-17]. Pediatr Neurol. 2016 11; 64:105. PMID: 27594203.
      View in: PubMed
    11. Fullerton HJ, deVeber GA, Hills NK, Dowling MM, Fox CK, Mackay MT, Kirton A, Yager JY, Bernard TJ, Hod EA, Wintermark M, Elkind MS. Inflammatory Biomarkers in Childhood Arterial Ischemic Stroke: Correlates of Stroke Cause and Recurrence. Stroke. 2016 09; 47(9):2221-8. PMID: 27491741.
      View in: PubMed
    12. Ritchey Z, Hollatz AL, Weitzenkamp D, Fenton LZ, Maxwell EC, Bernard TJ, Stence NV. Pediatric Cortical Vein Thrombosis: Frequency and Association With Venous Infarction. Stroke. 2016 Mar; 47(3):866-8. PMID: 26888536; PMCID: PMC4859822 [Available on 03/01/17].
    13. Rivkin MJ, Bernard TJ, Dowling MM, Amlie-Lefond C. Guidelines for Urgent Management of Stroke in Children. Pediatr Neurol. 2016 Mar; 56:8-17. PMID: 26969237.
      View in: PubMed
    14. Bernard TJ, Friedman NR, Stence NV, Jones W, Ichord R, Amlie-Lefond C, Dowling MM, Rivkin MJ. Preparing for a "Pediatric Stroke Alert". Pediatr Neurol. 2016 Mar; 56:18-24. PMID: 26969238.
      View in: PubMed
    15. Amlie-Lefond C, Rivkin MJ, Friedman NR, Bernard TJ, Dowling MM, deVeber G. The Way Forward: Challenges and Opportunities in Pediatric Stroke. Pediatr Neurol. 2016 Mar; 56:3-7. PMID: 26803334.
      View in: PubMed
    16. Press CA, Lindsay A, Stence NV, Fenton LZ, Bernard TJ, Mirsky DM. Cavernous Sinus Thrombosis in Children: Imaging Characteristics and Clinical Outcomes. Stroke. 2015 Sep; 46(9):2657-60. PMID: 26251243.
      View in: PubMed
    17. Goldenberg NA, Everett AD, Graham D, Bernard TJ, Nowak-Göttl U. Proteomic and other mass spectrometry based "omics" biomarker discovery and validation in pediatric venous thromboembolism and arterial ischemic stroke: current state, unmet needs, and future directions. Proteomics Clin Appl. 2014 Dec; 8(11-12):828-36. PMID: 25379629.
      View in: PubMed
    18. Wintermark M, Hills NK, deVeber GA, Barkovich AJ, Elkind MS, Sear K, Zhu G, Leiva-Salinas C, Hou Q, Dowling MM, Bernard TJ, Friedman NR, Ichord RN, Fullerton HJ. Arteriopathy diagnosis in childhood arterial ischemic stroke: results of the vascular effects of infection in pediatric stroke study. Stroke. 2014 Dec; 45(12):3597-605. PMID: 25388419; PMCID: PMC4260818.
    19. Baird LC, Smith ER, Ichord R, Piccoli DA, Bernard TJ, Spinner NB, Scott RM, Kamath BM. Moyamoya syndrome associated with Alagille syndrome: outcome after surgical revascularization. J Pediatr. 2015 Feb; 166(2):470-3. PMID: 25465847.
      View in: PubMed
    20. Sinclair AJ, Fox CK, Ichord RN, Almond CS, Bernard TJ, Beslow LA, Chan AK, Cheung M, deVeber G, Dowling MM, Friedman N, Giglia TM, Guilliams KP, Humpl T, Licht DJ, Mackay MT, Jordan LC. Stroke in children with cardiac disease: report from the International Pediatric Stroke Study Group Symposium. Pediatr Neurol. 2015 Jan; 52(1):5-15. PMID: 25532775; PMCID: PMC4936915.
    21. Poisson SN, Schardt TQ, Dingman A, Bernard TJ. Etiology and treatment of arterial ischemic stroke in children and young adults. Curr Treat Options Neurol. 2014 Oct; 16(10):315. PMID: 25227455.
      View in: PubMed
    22. Plumb P, Seiber E, Dowling MM, Lee J, Bernard TJ, deVeber G, Ichord RN, Bastian R, Lo WD. Out-of-pocket costs for childhood stroke: the impact of chronic illness on parents' pocketbooks. Pediatr Neurol. 2015 Jan; 52(1):73-6.e2. PMID: 25447931; PMCID: PMC4276532.
    23. Bernard TJ, Rivkin MJ, Scholz K, deVeber G, Kirton A, Gill JC, Chan AK, Hovinga CA, Ichord RN, Grotta JC, Jordan LC, Benedict S, Friedman NR, Dowling MM, Elbers J, Torres M, Sultan S, Cummings DD, Grabowski EF, McMillan HJ, Beslow LA, Amlie-Lefond C. Emergence of the primary pediatric stroke center: impact of the thrombolysis in pediatric stroke trial. Stroke. 2014 Jul; 45(7):2018-23. PMID: 24916908; PMCID: PMC4083478.
    24. Joachim E, Goldenberg NA, Bernard TJ, Armstrong-Wells J, Stabler S, Manco-Johnson MJ. The methylenetetrahydrofolate reductase polymorphism (MTHFR c.677C>T) and elevated plasma homocysteine levels in a U.S. pediatric population with incident thromboembolism. Thromb Res. 2013 Aug; 132(2):170-4. PMID: 23866722; PMCID: PMC4115647.
    25. Goldenberg NA, Bernard TJ, Hillhouse J, Armstrong-Wells J, Galinkin J, Knapp-Clevenger R, Jacobson L, Marcovina SM, Manco-Johnson MJ. Elevated lipoprotein (a), small apolipoprotein (a), and the risk of arterial ischemic stroke in North American children. Haematologica. 2013 May; 98(5):802-7. PMID: 23349301; PMCID: PMC3640128.
    26. Bernard TJ, Armstrong-Wells J, Goldenberg NA. The institution-based prospective inception cohort study: design, implementation, and quality assurance in pediatric thrombosis and stroke research. Semin Thromb Hemost. 2013 Feb; 39(1):10-4. PMID: 23269572; PMCID: PMC4115646.
    27. Goldenberg NA, Jenkins S, Jack J, Armstrong-Wells J, Fenton LZ, Stence NV, Oleszek J, Boada R, Wilkening GN, Wilkinson C, Soep JB, Miyamoto SD, Bajaj L, Mourani PM, Manco-Johnson MJ, Bernard TJ. Arteriopathy, D-dimer, and risk of poor neurologic outcome in childhood-onset arterial ischemic stroke. J Pediatr. 2013 May; 162(5):1041-6.e1. PMID: 23260102; PMCID: PMC4115645.
    28. Lambers M, Goldenberg NA, Kenet G, Kirkham FJ, Manner D, Bernard T, Mesters RM, Junker R, Stoll M, Nowak-Göttl U. Role of reduced ADAMTS13 in arterial ischemic stroke: a pediatric cohort study. Ann Neurol. 2013 Jan; 73(1):58-64. PMID: 23225307; PMCID: PMC3703929.
    29. Flett KB, Rao S, Dominguez SR, Bernard T, Glode MP. Variability in the Diagnosis of Encephalitis by Pediatric Subspecialists: The Need For a Uniform Definition. J Pediatric Infect Dis Soc. 2013 Sep; 2(3):267-9. PMID: 26619481.
      View in: PubMed
    30. Pearson V, Ruzas C, Krebs NF, Goldenberg NA, Manco-Johnson MJ, Bernard TJ. Overweight and obesity are increased in childhood-onset cerebrovascular disease. J Child Neurol. 2013 Apr; 28(4):517-9. PMID: 22647484; PMCID: PMC3697108.
    31. Kedia S, Stence N, Manco-Johnson M, Armstrong-Wells J, Bernard TJ. Late cytotoxic edema in 2 children with hemiplegia: hemiplegic migraine or stroke? Headache. 2012 Apr; 52(4):674-8. PMID: 22404149; PMCID: PMC3682476.
    32. Lyle CA, Bernard TJ, Goldenberg NA. Childhood arterial ischemic stroke: a review of etiologies, antithrombotic treatments, prognostic factors, and priorities for future research. Semin Thromb Hemost. 2011 Oct; 37(7):786-93. PMID: 22187401; PMCID: PMC3679654.
    33. Bernard TJ, Manco-Johnson MJ, Lo W, MacKay MT, Ganesan V, DeVeber G, Goldenberg NA, Armstrong-Wells J, Dowling MM, Roach ES, Tripputi M, Fullerton HJ, Furie KL, Benseler SM, Jordan LC, Kirton A, Ichord R. Towards a consensus-based classification of childhood arterial ischemic stroke. Stroke. 2012 Feb; 43(2):371-7. PMID: 22156694; PMCID: PMC3312781.
    34. Stence NV, Fenton LZ, Goldenberg NA, Armstrong-Wells J, Bernard TJ. Craniocervical arterial dissection in children: diagnosis and treatment. Curr Treat Options Neurol. 2011 Dec; 13(6):636-48. PMID: 21979145; PMCID: PMC3297486.
    35. Beslow LA, Kasner SE, Smith SE, Mullen MT, Kirschen MP, Bastian RA, Dowling MM, Lo W, Jordan LC, Bernard TJ, Friedman N, DeVeber G, Kirton A, Abraham L, Licht DJ, Jawad AF, Ellenberg JH, Lautenbach E, Ichord RN. Concurrent validity and reliability of retrospective scoring of the Pediatric National Institutes of Health Stroke Scale. Stroke. 2012 Feb; 43(2):341-5. PMID: 22076000; PMCID: PMC3265644.
    36. Ichord RN, Bastian R, Abraham L, Askalan R, Benedict S, Bernard TJ, Beslow L, Deveber G, Dowling M, Friedman N, Fullerton H, Jordan L, Kan L, Kirton A, Amlie-Lefond C, Licht D, Lo W, McClure C, Pavlakis S, Smith SE, Tan M, Kasner S, Jawad AF. Interrater reliability of the Pediatric National Institutes of Health Stroke Scale (PedNIHSS) in a multicenter study. Stroke. 2011 Mar; 42(3):613-7. PMID: 21317270; PMCID: PMC3065389.
    37. Bernard TJ, Manco-Johnson MJ, Goldenberg NA. The roles of anatomic factors, thrombophilia, and antithrombotic therapies in childhood-onset arterial ischemic stroke. Thromb Res. 2011 Jan; 127(1):6-12. PMID: 20947137; PMCID: PMC3204859.
    38. Kenet G, Lütkhoff LK, Albisetti M, Bernard T, Bonduel M, Brandao L, Chabrier S, Chan A, deVeber G, Fiedler B, Fullerton HJ, Goldenberg NA, Grabowski E, Günther G, Heller C, Holzhauer S, Iorio A, Journeycake J, Junker R, Kirkham FJ, Kurnik K, Lynch JK, Male C, Manco-Johnson M, Mesters R, Monagle P, van Ommen CH, Raffini L, Rostásy K, Simioni P, Sträter RD, Young G, Nowak-Göttl U. Impact of thrombophilia on risk of arterial ischemic stroke or cerebral sinovenous thrombosis in neonates and children: a systematic review and meta-analysis of observational studies. Circulation. 2010 Apr 27; 121(16):1838-47. PMID: 20385928.
      View in: PubMed
    39. Bernard TJ, Goldenberg NA. Pediatric arterial ischemic stroke. Hematol Oncol Clin North Am. 2010 Feb; 24(1):167-80. PMID: 20113901.
      View in: PubMed
    40. Goldenberg NA, Bernard TJ. Venous thromboembolism in children. Hematol Oncol Clin North Am. 2010 Feb; 24(1):151-66. PMID: 20113900.
      View in: PubMed
    41. Armstrong-Wells J, Bernard TJ, Boada R, Manco-Johnson M. Neurocognitive outcomes following neonatal encephalopathy. NeuroRehabilitation. 2010; 26(1):27-33. PMID: 20130353.
      View in: PubMed
    42. Bernard TJ, Fenton LZ, Apkon SD, Boada R, Wilkening GN, Wilkinson CC, Soep JB, Miyamoto SD, Tripputi M, Armstrong-Wells J, Benke TA, Manco-Johnson MJ, Goldenberg NA. Biomarkers of hypercoagulability and inflammation in childhood-onset arterial ischemic stroke. J Pediatr. 2010 Apr; 156(4):651-6. PMID: 20022340.
      View in: PubMed
    43. Normann S, de Veber G, Fobker M, Langer C, Kenet G, Bernard TJ, Fiedler B, Sträter R, Goldenberg NA, Nowak-Göttl U. Role of endogenous testosterone concentration in pediatric stroke. Ann Neurol. 2009 Dec; 66(6):754-8. PMID: 20033984.
      View in: PubMed
    44. Goldenberg NA, Bernard TJ, Fullerton HJ, Gordon A, deVeber G. Antithrombotic treatments, outcomes, and prognostic factors in acute childhood-onset arterial ischaemic stroke: a multicentre, observational, cohort study. Lancet Neurol. 2009 Dec; 8(12):1120-7. PMID: 19801204.
      View in: PubMed
    45. Bernard TJ, Goldenberg NA, Tripputi M, Manco-Johnson MJ, Niederstadt T, Nowak-Göttl U. Anticoagulation in childhood-onset arterial ischemic stroke with non-moyamoya arteriopathy: findings from the Colorado and German (COAG) collaboration. Stroke. 2009 Aug; 40(8):2869-71. PMID: 19478216; PMCID: PMC4115644.
    46. Amlie-Lefond C, deVeber G, Chan AK, Benedict S, Bernard T, Carpenter J, Dowling MM, Fullerton H, Hovinga C, Kirton A, Lo W, Zamel K, Ichord R. Use of alteplase in childhood arterial ischaemic stroke: a multicentre, observational, cohort study. Lancet Neurol. 2009 Jun; 8(6):530-6. PMID: 19423401.
      View in: PubMed
    47. Amlie-Lefond C, Bernard TJ, Sébire G, Friedman NR, Heyer GL, Lerner NB, DeVeber G, Fullerton HJ. Predictors of cerebral arteriopathy in children with arterial ischemic stroke: results of the International Pediatric Stroke Study. Circulation. 2009 Mar 17; 119(10):1417-23. PMID: 19255344; PMCID: PMC4205969.
    48. Bernard TJ, Goldenberg NA, Armstrong-Wells J, Amlie-Lefond C, Fullerton HJ. Treatment of childhood arterial ischemic stroke. Ann Neurol. 2008 Jun; 63(6):679-96. PMID: 18496844.
      View in: PubMed
    49. Goldenberg NA, Bernard TJ. Venous thromboembolism in children. Pediatr Clin North Am. 2008 Apr; 55(2):305-22, vii. PMID: 18381088.
      View in: PubMed
    50. Bernard TJ, Goldenberg NA. Pediatric arterial ischemic stroke. Pediatr Clin North Am. 2008 Apr; 55(2):323-38, viii. PMID: 18381089.
      View in: PubMed
    51. Bernard TJ, deVeber GA, Benke TA. Athletic participation after acute ischemic childhood stroke: a survey of pediatric stroke experts. J Child Neurol. 2007 Aug; 22(8):1050-3. PMID: 17761660.
      View in: PubMed
    52. Bernard TJ, Mull BR, Handler MH, Harned RK, Filley CM, Kumpe DA, Tseng BS. An 18-year-old man with fenestrated vertebral arteries, recurrent stroke and successful angiographic coiling. J Neurol Sci. 2007 Sep 15; 260(1-2):279-82. PMID: 17568613; PMCID: PMC2925646.
    53. Hudson LA, Bernard TJ, Tseng BS, Miller BR, Corboy JR. Neuromyelitis optica immunoglobulin G in a child. Pediatr Neurol. 2006 Nov; 35(5):370-2. PMID: 17074612; PMCID: PMC2918874.
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