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Kristin Bruk Artinger

InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSDM-Craniofacial Biology

    Collapse Research 
    Collapse research activities and funding
    F32HD008209     (ARTINGER, KRISTIN BRUK)Jul 1, 1997
    Role: Principal Investigator

    K22DE014200     (ARTINGER, KRISTIN BRUK)Aug 15, 2001 - Jul 31, 2006
    Neural crest cell specification - zebrafish and Xenopus
    Role: Principal Investigator

    R01HD050698     (ARTINGER, KRISTIN BRUK)Apr 1, 2006 - Jan 31, 2012
    The role of prdm1 in neural cell fate specification
    Role: Principal Investigator

    R01DE017699     (ARTINGER, KRISTIN BRUK)Aug 1, 2007 - Jul 31, 2014
    Role: Principal Investigator

    U01DE020076     (CLOUTHIER, DAVID E.)Sep 21, 2009 - Apr 30, 2014
    Idenfication of miRNAs involved midfacial development and clefting
    Role: Co-Principal Investigator

    R01DE024034     (ARTINGER, KRISTIN)Jul 1, 2015 - May 31, 2020
    Function of chromatin modifiers in cranial neural crest development
    Role: Principal Investigator

    R21CA201809     (FORD, HEIDE L.)Jul 1, 2016 - Jun 30, 2018
    Using zebrafish to study the role of six1a/b and microRNA-30a in rhabdomyosarcoma (RMS) initiation and progression
    Role: Co-Principal Investigator

    R03HD096320     (ARTINGER, KRISTIN)Apr 5, 2019 - Mar 31, 2021
    Mechanistic analysis of novel genetic loci for split hand foot malformation
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Sen R, Pezoa SA, Carpio Shull L, Hernandez-Lagunas L, Niswander LA, Artinger KB. Kat2a and Kat2b Acetyltransferase Activity Regulates Craniofacial Cartilage and Bone Differentiation in Zebrafish and Mice. J Dev Biol. 2018 Nov 12; 6(4). PMID: 30424580.
      View in: PubMed
    2. Williams JS, Hsu JY, Rossi CC, Artinger KB. Requirement of zebrafish pcdh10a and pcdh10b in melanocyte precursor migration. Dev Biol. 2018 Dec 01; 444 Suppl 1:S274-S286. PMID: 29604249.
      View in: PubMed
    3. Artinger KB, Alfandari D, Taneyhill LA. Editorial. Mech Dev. 2017 12; 148:1-2. PMID: 28757382.
      View in: PubMed
    4. Ding HL, Hooper JE, Batzel P, Eames BF, Postlethwait JH, Artinger KB, Clouthier DE. MicroRNA Profiling during Craniofacial Development: Potential Roles for Mir23b and Mir133b. Front Physiol. 2016; 7:281. PMID: 27471470; PMCID: PMC4943961.
    5. Van Otterloo E, Williams T, Artinger KB. The old and new face of craniofacial research: How animal models inform human craniofacial genetic and clinical data. Dev Biol. 2016 07 15; 415(2):171-187. PMID: 26808208; PMCID: PMC4914413 [Available on 07/15/17].
    6. Tavares AL, Artinger KB, Clouthier DE. Regulating Craniofacial Development at the 3' End: MicroRNAs and Their Function in Facial Morphogenesis. Curr Top Dev Biol. 2015; 115:335-75. PMID: 26589932.
      View in: PubMed
    7. Powell DR, Williams JS, Hernandez-Lagunas L, Salcedo E, O'Brien JH, Artinger KB. Cdon promotes neural crest migration by regulating N-cadherin localization. Dev Biol. 2015 Nov 15; 407(2):289-99. PMID: 26256768; PMCID: PMC4663112 [Available on 11/15/16].
    8. Shellman YG, Lambert KA, Brauweiler A, Fain P, Spritz RA, Martini M, Janssen KP, Box NF, Terzian T, Rewers M, Horvath A, Stratakis CA, Robinson WA, Robinson SE, Norris DA, Artinger KB, Pacheco TR. SASH1 Is Involved in an Autosomal Dominant Lentiginous Phenotype. J Invest Dermatol. 2015 Dec; 135(12):3192-3194. PMID: 26203640; PMCID: PMC4648645.
    9. Van Laarhoven PM, Neitzel LR, Quintana AM, Geiger EA, Zackai EH, Clouthier DE, Artinger KB, Ming JE, Shaikh TH. Kabuki syndrome genes KMT2D and KDM6A: functional analyses demonstrate critical roles in craniofacial, heart and brain development. Hum Mol Genet. 2015 Aug 01; 24(15):4443-53. PMID: 25972376; PMCID: PMC4492403.
    10. LaMonica K, Ding HL, Artinger KB. prdm1a functions upstream of itga5 in zebrafish craniofacial development. Genesis. 2015 Mar-Apr; 53(3-4):270-7. PMID: 25810090; PMCID: PMC4411201.
    11. Quintana AM, Geiger EA, Achilly N, Rosenblatt DS, Maclean KN, Stabler SP, Artinger KB, Appel B, Shaikh TH. Hcfc1b, a zebrafish ortholog of HCFC1, regulates craniofacial development by modulating mmachc expression. Dev Biol. 2014 Dec 01; 396(1):94-106. PMID: 25281006; PMCID: PMC4391465.
    12. O'Brien JH, Hernandez-Lagunas L, Artinger KB, Ford HL. MicroRNA-30a regulates zebrafish myogenesis through targeting the transcription factor Six1. J Cell Sci. 2014 May 15; 127(Pt 10):2291-301. PMID: 24634509; PMCID: PMC4021474.
    13. Powell DR, Hernandez-Lagunas L, LaMonica K, Artinger KB. Prdm1a directly activates foxd3 and tfap2a during zebrafish neural crest specification. Development. 2013 Aug; 140(16):3445-55. PMID: 23900542; PMCID: PMC3737723.
    14. Melvin VS, Feng W, Hernandez-Lagunas L, Artinger KB, Williams T. A morpholino-based screen to identify novel genes involved in craniofacial morphogenesis. Dev Dyn. 2013 Jul; 242(7):817-31. PMID: 23559552; PMCID: PMC4027977.
    15. Powell DR, Blasky AJ, Britt SG, Artinger KB. Riding the crest of the wave: parallels between the neural crest and cancer in epithelial-to-mesenchymal transition and migration. Wiley Interdiscip Rev Syst Biol Med. 2013 Jul-Aug; 5(4):511-22. PMID: 23576382; PMCID: PMC3739939.
    16. Ding HL, Clouthier DE, Artinger KB. Redundant roles of PRDM family members in zebrafish craniofacial development. Dev Dyn. 2013 Jan; 242(1):67-79. PMID: 23109401.
      View in: PubMed
    17. Iklé JM, Artinger KB, Clouthier DE. Identification and characterization of the zebrafish pharyngeal arch-specific enhancer for the basic helix-loop-helix transcription factor Hand2. Dev Biol. 2012 Aug 01; 368(1):118-26. PMID: 22595513; PMCID: PMC3676283.
    18. Anderson KR, Singer RA, Balderes DA, Hernandez-Lagunas L, Johnson CW, Artinger KB, Sussel L. The L6 domain tetraspanin Tm4sf4 regulates endocrine pancreas differentiation and directed cell migration. Development. 2011 Aug; 138(15):3213-24. PMID: 21750032; PMCID: PMC3133913.
    19. Johnson CW, Hernandez-Lagunas L, Feng W, Melvin VS, Williams T, Artinger KB. Vgll2a is required for neural crest cell survival during zebrafish craniofacial development. Dev Biol. 2011 Sep 01; 357(1):269-81. PMID: 21741961; PMCID: PMC3519931.
    20. Hernandez-Lagunas L, Powell DR, Law J, Grant KA, Artinger KB. prdm1a and olig4 act downstream of Notch signaling to regulate cell fate at the neural plate border. Dev Biol. 2011 Aug 15; 356(2):496-505. PMID: 21689645; PMCID: PMC3144709.
    21. Hochheiser H, Aronow BJ, Artinger K, Beaty TH, Brinkley JF, Chai Y, Clouthier D, Cunningham ML, Dixon M, Donahue LR, Fraser SE, Hallgrimsson B, Iwata J, Klein O, Marazita ML, Murray JC, Murray S, de Villena FP, Postlethwait J, Potter S, Shapiro L, Spritz R, Visel A, Weinberg SM, Trainor PA. The FaceBase Consortium: a comprehensive program to facilitate craniofacial research. Dev Biol. 2011 Jul 15; 355(2):175-82. PMID: 21458441; PMCID: PMC3440302.
    22. Olesnicky E, Hernandez-Lagunas L, Artinger KB. prdm1a Regulates sox10 and islet1 in the development of neural crest and Rohon-Beard sensory neurons. Genesis. 2010 Nov; 48(11):656-66. PMID: 20836130; PMCID: PMC3119337.
    23. Klymkowsky MW, Rossi CC, Artinger KB. Mechanisms driving neural crest induction and migration in the zebrafish and Xenopus laevis. Cell Adh Migr. 2010 Oct-Dec; 4(4):595-608. PMID: 20962584; PMCID: PMC3011258.
    24. Artinger KB. The fascinating world of neural crest cells. Cell Adh Migr. 2010 Oct-Dec; 4(4):551-2. PMID: 21504078; PMCID: PMC3011269.
    25. Birkholz DA, Olesnicky Killian EC, George KM, Artinger KB. Prdm1a is necessary for posterior pharyngeal arch development in zebrafish. Dev Dyn. 2009 Oct; 238(10):2575-87. PMID: 19777590.
      View in: PubMed
    26. Kaji T, Shimizu K, Artinger KB, Yasui K. Dynamic modification of oral innervation during metamorphosis in Branchiostoma belcheri, the oriental lancelet. Biol Bull. 2009 Oct; 217(2):151-60. PMID: 19875820.
      View in: PubMed
    27. Olesnicky Killian EC, Birkholz DA, Artinger KB. A role for chemokine signaling in neural crest cell migration and craniofacial development. Dev Biol. 2009 Sep 01; 333(1):161-72. PMID: 19576198; PMCID: PMC2728170.
    28. Rossi CC, Kaji T, Artinger KB. Transcriptional control of Rohon-Beard sensory neuron development at the neural plate border. Dev Dyn. 2009 Apr; 238(4):931-43. PMID: 19301392; PMCID: PMC2755227.
    29. Clouthier DE, Gray J, Artinger KB. Micromanaging Palate Development. Perspect Speech Sci Orofac Disord. 2008 Oct 01; 18(2):62-72. PMID: 20016765.
      View in: PubMed
    30. Rossi CC, Hernandez-Lagunas L, Zhang C, Choi IF, Kwok L, Klymkowsky M, Artinger KB. Rohon-Beard sensory neurons are induced by BMP4 expressing non-neural ectoderm in Xenopus laevis. Dev Biol. 2008 Feb 15; 314(2):351-61. PMID: 18191829; PMCID: PMC2262044.
    31. Wenzlau JM, Garl PJ, Simpson P, Stenmark KR, West J, Artinger KB, Nemenoff RA, Weiser-Evans MC. Embryonic growth-associated protein is one subunit of a novel N-terminal acetyltransferase complex essential for embryonic vascular development. Circ Res. 2006 Mar 31; 98(6):846-55. PMID: 16484612.
      View in: PubMed
    32. Hernandez-Lagunas L, Choi IF, Kaji T, Simpson P, Hershey C, Zhou Y, Zon L, Mercola M, Artinger KB. Zebrafish narrowminded disrupts the transcription factor prdm1 and is required for neural crest and sensory neuron specification. Dev Biol. 2005 Feb 15; 278(2):347-57. PMID: 15680355; PMCID: PMC4028833.
    33. Kaji T, Artinger KB. dlx3b and dlx4b function in the development of Rohon-Beard sensory neurons and trigeminal placode in the zebrafish neurula. Dev Biol. 2004 Dec 15; 276(2):523-40. PMID: 15581883; PMCID: PMC4027963.
    34. Zhang C, Basta T, Hernandez-Lagunas L, Simpson P, Stemple DL, Artinger KB, Klymkowsky MW. Repression of nodal expression by maternal B1-type SOXs regulates germ layer formation in Xenopus and zebrafish. Dev Biol. 2004 Sep 01; 273(1):23-37. PMID: 15302595.
      View in: PubMed
    35. Woda JM, Pastagia J, Mercola M, Artinger KB. Dlx proteins position the neural plate border and determine adjacent cell fates. Development. 2003 Jan; 130(2):331-42. PMID: 12466200; PMCID: PMC4018238.
    36. Belting HG, Hauptmann G, Meyer D, Abdelilah-Seyfried S, Chitnis A, Eschbach C, Söll I, Thisse C, Thisse B, Artinger KB, Lunde K, Driever W. spiel ohne grenzen/pou2 is required during establishment of the zebrafish midbrain-hindbrain boundary organizer. Development. 2001 Nov; 128(21):4165-76. PMID: 11684654; PMCID: PMC4027960.
    37. Kim CH, Oda T, Itoh M, Jiang D, Artinger KB, Chandrasekharappa SC, Driever W, Chitnis AB. Repressor activity of Headless/Tcf3 is essential for vertebrate head formation. Nature. 2000 Oct 19; 407(6806):913-6. PMID: 11057671; PMCID: PMC4018833.
    38. Artinger KB, Chitnis AB, Mercola M, Driever W. Zebrafish narrowminded suggests a genetic link between formation of neural crest and primary sensory neurons. Development. 1999 Sep; 126(18):3969-79. PMID: 10457007.
      View in: PubMed
    39. Selleck MA, García-Castro MI, Artinger KB, Bronner-Fraser M. Effects of Shh and Noggin on neural crest formation demonstrate that BMP is required in the neural tube but not ectoderm. Development. 1998 Dec; 125(24):4919-30. PMID: 9811576.
      View in: PubMed
    40. Ruffins S, Artinger KB, Bronner-Fraser M. Early migrating neural crest cells can form ventral neural tube derivatives when challenged by transplantation. Dev Biol. 1998 Nov 15; 203(2):295-304. PMID: 9808781.
      View in: PubMed
    41. Artinger KB, Fedtsova N, Rhee JM, Bronner-Fraser M, Turner E. Placodal origin of Brn-3-expressing cranial sensory neurons. J Neurobiol. 1998 Sep 15; 36(4):572-85. PMID: 9740028.
      View in: PubMed
    42. Artinger KB, Fraser S, Bronner-Fraser M. Dorsal and ventral cell types can arise from common neural tube progenitors. Dev Biol. 1995 Dec; 172(2):591-601. PMID: 8612974.
      View in: PubMed
    43. Artinger KB, Bronner-Fraser M. Notochord grafts do not suppress formation of neural crest cells or commissural neurons. Development. 1992 Dec; 116(4):877-86. PMID: 1295741.
      View in: PubMed
    44. Lallier T, Leblanc G, Artinger KB, Bronner-Fraser M. Cranial and trunk neural crest cells use different mechanisms for attachment to extracellular matrices. Development. 1992 Nov; 116(3):531-41. PMID: 1289052.
      View in: PubMed
    45. Artinger KB, Bronner-Fraser M. Partial restriction in the developmental potential of late emigrating avian neural crest cells. Dev Biol. 1992 Jan; 149(1):149-57. PMID: 1728584.
      View in: PubMed
    46. Stern CD, Artinger KB, Bronner-Fraser M. Tissue interactions affecting the migration and differentiation of neural crest cells in the chick embryo. Development. 1991 Sep; 113(1):207-16. PMID: 1764996.
      View in: PubMed
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