Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Jacob Friedman

TitleProfessor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-PEDS
Phone303/724-3983

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    F32DK008477     (FRIEDMAN, JACOB E)Sep 1, 1990
    NIH/NIDDK
    REGULATION OF GLUCOSE TRANSPORTERS IN OBESITY &NIDDM
    Role: Principal Investigator

    R29DK050272     (FRIEDMAN, JACOB E)Jul 1, 1996 - Jun 30, 2001
    NIH/NIDDK
    REGULATION OF GLUCONEOGENESIS IN EXERCISE AND DIABETES
    Role: Principal Investigator

    R01DK059767     (FRIEDMAN, JACOB E)Sep 15, 2000 - Jun 30, 2012
    NIH/NIDDK
    Regulation of glucose homeostasis by C/EBPB
    Role: Principal Investigator

    R01DK062155     (FRIEDMAN, JACOB E)Apr 1, 2003 - Aug 31, 2007
    NIH/NIDDK
    Mechanisms of Insulin Resistance in GDM
    Role: Principal Investigator

    R01DK078590     (FRIEDMAN, JACOB E)Jul 9, 2007 - Jun 30, 2012
    NIH/NIDDK
    MECHANISMS FOR FETAL HEPATIC PROGRAMMING IN THE NON-HUMAN PRIMATE (NHP)
    Role: Principal Investigator

    R21DK088324     (BARBOUR, LINDA ANNE)Apr 20, 2010 - Mar 31, 2013
    NIH/NIDDK
    Role of Macronutrient Diet Composition on Maternal and Infant Metabolic Outcomes
    Role: Co-Principal Investigator

    R24DK090964     (FRIEDMAN, JACOB E)Sep 25, 2010 - Jul 31, 2020
    NIH/NIDDK
    Interrupting the Vicious Cycle of Obesity and Metabolic Syndrome
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Baker PR, Patinkin Z, Shapiro AL, De La Houssaye BA, Woontner M, Boyle KE, Vanderlinden L, Dabelea D, Friedman JE. Maternal obesity and increased neonatal adiposity correspond with altered infant mesenchymal stem cell metabolism. JCI Insight. 2017 Nov 02; 2(21). PMID: 29093265.
      View in: PubMed
    2. Boyle KE, Patinkin ZW, Shapiro ALB, Bader C, Vanderlinden L, Kechris K, Janssen RC, Ford RJ, Smith BK, Steinberg GR, Davidson EJ, Yang IV, Dabelea D, Friedman JE. Maternal obesity alters fatty acid oxidation, AMPK activity, and associated DNA methylation in mesenchymal stem cells from human infants. Mol Metab. 2017 Nov; 6(11):1503-1516. PMID: 29107296.
      View in: PubMed
    3. Mulligan CM, Friedman JE. Maternal modifiers of the infant gut microbiota: metabolic consequences. J Endocrinol. 2017 Oct; 235(1):R1-R12. PMID: 28751453.
      View in: PubMed
    4. Young BE, Patinkin Z, Palmer C, de la Houssaye B, Barbour LA, Hernandez T, Friedman JE, Krebs NF. Human milk insulin is related to maternal plasma insulin and BMI: but other components of human milk do not differ by BMI. Eur J Clin Nutr. 2017 Sep; 71(9):1094-1100. PMID: 28513622.
      View in: PubMed
    5. Friedman JE. The maternal microbiome: Cause or consequence of obesity risk in the next generation? Obesity (Silver Spring). 2017 Mar; 25(3):497-498. PMID: 28177586.
      View in: PubMed
    6. Soto SM, Blake AC, Wesolowski SR, Rozance PJ, Barthel KB, Gao B, Hetrick B, McCurdy CE, Garza NG, Hay WW, Leinwand LA, Friedman JE, Brown LD. Myoblast replication is reduced in the IUGR fetus despite maintained proliferative capacity in vitro. J Endocrinol. 2017 03; 232(3):475-491. PMID: 28053000.
      View in: PubMed
    7. Friedman JE, Young BE, Lemas DJ, Barbour LA, Frank DN, Santorico SA. Reply to M Gotteland and F Magne. Am J Clin Nutr. 2017 Jan; 105(1):234-236. PMID: 28049665.
      View in: PubMed
    8. Jonscher KR, Stewart MS, Alfonso-Garcia A, DeFelice BC, Wang XX, Luo Y, Levi M, Heerwagen MJ, Janssen RC, de la Houssaye BA, Wiitala E, Florey G, Jonscher RL, Potma EO, Fiehn O, Friedman JE. Early PQQ supplementation has persistent long-term protective effects on developmental programming of hepatic lipotoxicity and inflammation in obese mice. FASEB J. 2017 Apr; 31(4):1434-1448. PMID: 28007783.
      View in: PubMed
    9. Rudolph MC, Young BE, Lemas DJ, Palmer CE, Hernandez TL, Barbour LA, Friedman JE, Krebs NF, MacLean PS. Early infant adipose deposition is positively associated with the n-6 to n-3 fatty acid ratio in human milk independent of maternal BMI. Int J Obes (Lond). 2017 Apr; 41(4):510-517. PMID: 27876761.
      View in: PubMed
    10. Harris RA, Alcott CE, Sullivan EL, Takahashi D, McCurdy CE, Comstock S, Baquero K, Blundell P, Frias AE, Kahr M, Suter M, Wesolowski S, Friedman JE, Grove KL, Aagaard KM. Genomic Variants Associated with Resistance to High Fat Diet Induced Obesity in a Primate Model. Sci Rep. 2016 Nov 04; 6:36123. PMID: 27811965.
      View in: PubMed
    11. Wesolowski SR, Kasmi KC, Jonscher KR, Friedman JE. Developmental origins of NAFLD: a womb with a clue. Nat Rev Gastroenterol Hepatol. 2017 Feb; 14(2):81-96. PMID: 27780972.
      View in: PubMed
    12. McCurdy CE, Schenk S, Hetrick B, Houck J, Drew BG, Kaye S, Lashbrook M, Bergman BC, Takahashi DL, Dean TA, Nemkov T, Gertsman I, Hansen KC, Philp A, Hevener AL, Chicco AJ, Aagaard KM, Grove KL, Friedman JE. Maternal obesity reduces oxidative capacity in fetal skeletal muscle of Japanese macaques. JCI Insight. 2016 Oct 06; 1(16):e86612. PMID: 27734025.
      View in: PubMed
    13. Boyle KE, Friedman JE, Janssen RC, Underkofler C, Houmard JA, Rasouli N. Metabolic Inflexibility with Obesity and the Effects of Fenofibrate on Skeletal Muscle Fatty Acid Oxidation. Horm Metab Res. 2017 Jan; 49(1):50-57. PMID: 28103623.
      View in: PubMed
    14. Boyle KE, Friedman JE, Janssen RC, Underkofler C, Houmard JA, Rasouli N. Metabolic Inflexibility with Obesity and the Effects of Fenofibrate on Skeletal Muscle Fatty Acid Oxidation. Horm Metab Res. 2016 Aug 02. PMID: 27485593.
      View in: PubMed
    15. Shapiro AL, Boyle KE, Dabelea D, Patinkin ZW, De la Houssaye B, Ringham BM, Glueck DH, Barbour LA, Norris JM, Friedman JE. Nicotinamide Promotes Adipogenesis in Umbilical Cord-Derived Mesenchymal Stem Cells and Is Associated with Neonatal Adiposity: The Healthy Start BabyBUMP Project. PLoS One. 2016; 11(7):e0159575. PMID: 27414406; PMCID: PMC4944979.
    16. Jonscher KR, Alfonso-Garcia A, Suhalim JL, Orlicky DJ, Potma EO, Ferguson VL, Bouxsein ML, Bateman TA, Stodieck LS, Levi M, Friedman JE, Gridley DS, Pecaut MJ. Correction: Spaceflight Activates Lipotoxic Pathways in Mouse Liver. PLoS One. 2016; 11(5):e0155282. PMID: 27145222.
      View in: PubMed
    17. Shapiro AL, Kaar JL, Crume TL, Starling AP, Siega-Riz AM, Ringham BM, Glueck DH, Norris JM, Barbour LA, Friedman JE, Dabelea D. Maternal diet quality in pregnancy and neonatal adiposity: the Healthy Start Study. Int J Obes (Lond). 2016 Jul; 40(7):1056-62. PMID: 27133623.
      View in: PubMed
    18. Lemas DJ, Young BE, Baker PR, Tomczik AC, Soderborg TK, Hernandez TL, de la Houssaye BA, Robertson CE, Rudolph MC, Ir D, Patinkin ZW, Krebs NF, Santorico SA, Weir T, Barbour LA, Frank DN, Friedman JE. Alterations in human milk leptin and insulin are associated with early changes in the infant intestinal microbiome. Am J Clin Nutr. 2016 May; 103(5):1291-300. PMID: 27140533; PMCID: PMC4841936 [Available on 05/01/17].
    19. Jonscher KR, Alfonso-Garcia A, Suhalim JL, Orlicky DJ, Potma EO, Ferguson VL, Bouxsein ML, Bateman TA, Stodieck LS, Levi M, Friedman JE, Gridley DS, Pecaut MJ. Spaceflight Activates Lipotoxic Pathways in Mouse Liver. PLoS One. 2016; 11(4):e0152877. PMID: 27097220; PMCID: PMC4838331.
    20. Rahman SM, Baquero KC, Choudhury M, Janssen RC, de la Houssaye BA, Sun M, Miyazaki-Anzai S, Wang S, Moustaid-Moussa N, Miyazaki M, Friedman JE. C/EBPß in bone marrow is essential for diet induced inflammation, cholesterol balance, and atherosclerosis. Atherosclerosis. 2016 Jul; 250:172-9. PMID: 27072340; PMCID: PMC4907836.
    21. Soderborg TK, Borengasser SJ, Barbour LA, Friedman JE. Microbial transmission from mothers with obesity or diabetes to infants: an innovative opportunity to interrupt a vicious cycle. Diabetologia. 2016 May; 59(5):895-906. PMID: 26843076; PMCID: PMC4829383 [Available on 05/01/17].
    22. Boyle KE, Patinkin ZW, Shapiro AL, Baker PR, Dabelea D, Friedman JE. Mesenchymal Stem Cells From Infants Born to Obese Mothers Exhibit Greater Potential for Adipogenesis: The Healthy Start BabyBUMP Project. Diabetes. 2016 Mar; 65(3):647-59. PMID: 26631736; PMCID: PMC4764150 [Available on 03/01/17].
    23. Cardel M, Lemas DJ, Jackson KH, Friedman JE, Fernández JR. Higher Intake of PUFAs Is Associated with Lower Total and Visceral Adiposity and Higher Lean Mass in a Racially Diverse Sample of Children. J Nutr. 2015 Sep; 145(9):2146-52. PMID: 26269238; PMCID: PMC4548162.
    24. Friedman JE. Obesity and Gestational Diabetes Mellitus Pathways for Programming in Mouse, Monkey, and Man—Where Do We Go Next? The 2014 Norbert Freinkel Award Lecture. Diabetes Care. 2015 Aug; 38(8):1402-11. PMID: 26207051; PMCID: PMC4512131.
    25. Brown LD, Rozance PJ, Bruce JL, Friedman JE, Hay WW, Wesolowski SR. Limited capacity for glucose oxidation in fetal sheep with intrauterine growth restriction. Am J Physiol Regul Integr Comp Physiol. 2015 Oct 15; 309(8):R920-8. PMID: 26224688; PMCID: PMC4666949 [Available on 10/15/16].
    26. Hernandez TL, Van Pelt RE, Anderson MA, Reece MS, Reynolds RM, de la Houssaye BA, Heerwagen M, Donahoo WT, Daniels LJ, Chartier-Logan C, Janssen RC, Friedman JE, Barbour LA. Women With Gestational Diabetes Mellitus Randomized to a Higher-Complex Carbohydrate/Low-Fat Diet Manifest Lower Adipose Tissue Insulin Resistance, Inflammation, Glucose, and Free Fatty Acids: A Pilot Study. Diabetes Care. 2016 Jan; 39(1):39-42. PMID: 26223240; PMCID: PMC4686845 [Available on 01/01/17].
    27. Barbour LA, Hernandez TL, Reynolds RM, Reece MS, Chartier-Logan C, Anderson MK, Kelly T, Friedman JE, Van Pelt RE. Striking differences in estimates of infant adiposity by new and old DXA software, PEAPOD and skin-folds at 2 weeks and 1 year of life. Pediatr Obes. 2016 08; 11(4):264-71. PMID: 26198967; PMCID: PMC4762753 [Available on 08/01/17].
    28. Lemas DJ, Brinton JT, Shapiro AL, Glueck DH, Friedman JE, Dabelea D. Associations of maternal weight status prior and during pregnancy with neonatal cardiometabolic markers at birth: the Healthy Start study. Int J Obes (Lond). 2015 Oct; 39(10):1437-42. PMID: 26055075; PMCID: PMC4596750.
    29. Shapiro AL, Schmiege SJ, Brinton JT, Glueck D, Crume TL, Friedman JE, Dabelea D. Testing the fuel-mediated hypothesis: maternal insulin resistance and glucose mediate the association between maternal and neonatal adiposity, the Healthy Start study. Diabetologia. 2015 May; 58(5):937-41. PMID: 25628236; PMCID: PMC4393770.
    30. Crume TL, Shapiro AL, Brinton JT, Glueck DH, Martinez M, Kohn M, Harrod C, Friedman JE, Dabelea D. Maternal fuels and metabolic measures during pregnancy and neonatal body composition: the healthy start study. J Clin Endocrinol Metab. 2015 Apr; 100(4):1672-80. PMID: 25574704; PMCID: PMC4399301.
    31. Boyle KE, Hwang H, Janssen RC, DeVente JM, Barbour LA, Hernandez TL, Mandarino LJ, Lappas M, Friedman JE. Gestational diabetes is characterized by reduced mitochondrial protein expression and altered calcium signaling proteins in skeletal muscle. PLoS One. 2014; 9(9):e106872. PMID: 25216282; PMCID: PMC4162568.
    32. El Kasmi KC, Pugliese SC, Riddle SR, Poth JM, Anderson AL, Frid MG, Li M, Pullamsetti SS, Savai R, Nagel MA, Fini MA, Graham BB, Tuder RM, Friedman JE, Eltzschig HK, Sokol RJ, Stenmark KR. Adventitial fibroblasts induce a distinct proinflammatory/profibrotic macrophage phenotype in pulmonary hypertension. J Immunol. 2014 Jul 15; 193(2):597-609. PMID: 24928992; PMCID: PMC4100597.
    33. Thorn SR, Baquero KC, Newsom SA, El Kasmi KC, Bergman BC, Shulman GI, Grove KL, Friedman JE. Early life exposure to maternal insulin resistance has persistent effects on hepatic NAFLD in juvenile nonhuman primates. Diabetes. 2014 Aug; 63(8):2702-13. PMID: 24705404; PMCID: PMC4113070.
    34. Hambidge KM, Krebs NF, Westcott JE, Garces A, Goudar SS, Kodkany BS, Pasha O, Tshefu A, Bose CL, Figueroa L, Goldenberg RL, Derman RJ, Friedman JE, Frank DN, McClure EM, Stolka K, Das A, Koso-Thomas M, Sundberg S. Preconception maternal nutrition: a multi-site randomized controlled trial. BMC Pregnancy Childbirth. 2014 Mar 20; 14:111. PMID: 24650219; PMCID: PMC4000057.
    35. Hernandez TL, Van Pelt RE, Anderson MA, Daniels LJ, West NA, Donahoo WT, Friedman JE, Barbour LA. A higher-complex carbohydrate diet in gestational diabetes mellitus achieves glucose targets and lowers postprandial lipids: a randomized crossover study. Diabetes Care. 2014; 37(5):1254-62. PMID: 24595632; PMCID: PMC3994935.
    36. Roberts VH, Pound LD, Thorn SR, Gillingham MB, Thornburg KL, Friedman JE, Frias AE, Grove KL. Beneficial and cautionary outcomes of resveratrol supplementation in pregnant nonhuman primates. FASEB J. 2014 Jun; 28(6):2466-77. PMID: 24563374; PMCID: PMC4021444.
    37. Martin-Murphy BV, You Q, Wang H, De La Houssaye BA, Reilly TP, Friedman JE, Ju C. Mice lacking natural killer T cells are more susceptible to metabolic alterations following high fat diet feeding. PLoS One. 2014; 9(1):e80949. PMID: 24465369; PMCID: PMC3896335.
    38. Hernandez TL, Anderson MA, Chartier-Logan C, Friedman JE, Barbour LA. Strategies in the nutritional management of gestational diabetes. Clin Obstet Gynecol. 2013 Dec; 56(4):803-15. PMID: 24047934; PMCID: PMC3921177.
    39. Brumbaugh DE, Friedman JE. Developmental origins of nonalcoholic fatty liver disease. Pediatr Res. 2014 Jan; 75(1-2):140-7. PMID: 24192698; PMCID: PMC4081536.
    40. Stewart MS, Heerwagen MJ, Friedman JE. Developmental programming of pediatric nonalcoholic fatty liver disease: redefining the"first hit". Clin Obstet Gynecol. 2013 Sep; 56(3):577-90. PMID: 23835912; PMCID: PMC3763993.
    41. Boyle KE, Newsom SA, Janssen RC, Lappas M, Friedman JE. Skeletal muscle MnSOD, mitochondrial complex II, and SIRT3 enzyme activities are decreased in maternal obesity during human pregnancy and gestational diabetes mellitus. J Clin Endocrinol Metab. 2013 Oct; 98(10):E1601-9. PMID: 23956348; PMCID: PMC3790616.
    42. Heerwagen MJ, Stewart MS, de la Houssaye BA, Janssen RC, Friedman JE. Transgenic increase in N-3/n-6 Fatty Acid ratio reduces maternal obesity-associated inflammation and limits adverse developmental programming in mice. PLoS One. 2013; 8(6):e67791. PMID: 23825686; PMCID: PMC3692451.
    43. Newsom SA, Boyle KE, Friedman JE. Sirtuin 3: A major control point for obesity-related metabolic diseases? Drug Discov Today Dis Mech. 2013 Jun 01; 10(1-2):e35-e40. PMID: 23997790.
      View in: PubMed
    44. Brumbaugh DE, Tearse P, Cree-Green M, Fenton LZ, Brown M, Scherzinger A, Reynolds R, Alston M, Hoffman C, Pan Z, Friedman JE, Barbour LA. Intrahepatic fat is increased in the neonatal offspring of obese women with gestational diabetes. J Pediatr. 2013 May; 162(5):930-6.e1. PMID: 23260099; PMCID: PMC3610780.
    45. Grant WF, Nicol LE, Thorn SR, Grove KL, Friedman JE, Marks DL. Perinatal exposure to a high-fat diet is associated with reduced hepatic sympathetic innervation in one-year old male Japanese macaques. PLoS One. 2012; 7(10):e48119. PMID: 23118937; PMCID: PMC3484148.
    46. DuBois BN, O'Tierney-Ginn P, Pearson J, Friedman JE, Thornburg K, Cherala G. Maternal obesity alters feto-placental cytochrome P4501A1 activity. Placenta. 2012 Dec; 33(12):1045-51. PMID: 23046808; PMCID: PMC3504187.
    47. Suter MA, Chen A, Burdine MS, Choudhury M, Harris RA, Lane RH, Friedman JE, Grove KL, Tackett AJ, Aagaard KM. A maternal high-fat diet modulates fetal SIRT1 histone and protein deacetylase activity in nonhuman primates. FASEB J. 2012 Dec; 26(12):5106-14. PMID: 22982377; PMCID: PMC3509051.
    48. Qadri I, Choudhury M, Rahman SM, Knotts TA, Janssen RC, Schaack J, Iwahashi M, Puljak L, Simon FR, Kilic G, Fitz JG, Friedman JE. Increased phosphoenolpyruvate carboxykinase gene expression and steatosis during hepatitis C virus subgenome replication: role of nonstructural component 5A and CCAAT/enhancer-binding protein ß. J Biol Chem. 2012 Oct 26; 287(44):37340-51. PMID: 22955269; PMCID: PMC3481331.
    49. Thorn SR, Brown LD, Rozance PJ, Hay WW, Friedman JE. Increased hepatic glucose production in fetal sheep with intrauterine growth restriction is not suppressed by insulin. Diabetes. 2013 Jan; 62(1):65-73. PMID: 22933111; PMCID: PMC3526037.
    50. Rahman SM, Janssen RC, Choudhury M, Baquero KC, Aikens RM, de la Houssaye BA, Friedman JE. CCAAT/enhancer-binding protein ß (C/EBPß) expression regulates dietary-induced inflammation in macrophages and adipose tissue in mice. J Biol Chem. 2012 Oct 05; 287(41):34349-60. PMID: 22902781; PMCID: PMC3464541.
    51. Neville MC, Anderson SM, McManaman JL, Badger TM, Bunik M, Contractor N, Crume T, Dabelea D, Donovan SM, Forman N, Frank DN, Friedman JE, German JB, Goldman A, Hadsell D, Hambidge M, Hinde K, Horseman ND, Hovey RC, Janoff E, Krebs NF, Lebrilla CB, Lemay DG, MacLean PS, Meier P, Morrow AL, Neu J, Nommsen-Rivers LA, Raiten DJ, Rijnkels M, Seewaldt V, Shur BD, VanHouten J, Williamson P. Lactation and neonatal nutrition: defining and refining the critical questions. J Mammary Gland Biol Neoplasia. 2012 Jun; 17(2):167-88. PMID: 22752723; PMCID: PMC3428522.
    52. McCurdy CE, Schenk S, Holliday MJ, Philp A, Houck JA, Patsouris D, MacLean PS, Majka SM, Klemm DJ, Friedman JE. Attenuated Pik3r1 expression prevents insulin resistance and adipose tissue macrophage accumulation in diet-induced obese mice. Diabetes. 2012 Oct; 61(10):2495-505. PMID: 22698915; PMCID: PMC3447911.
    53. Brown LD, Rozance PJ, Thorn SR, Friedman JE, Hay WW. Acute supplementation of amino acids increases net protein accretion in IUGR fetal sheep. Am J Physiol Endocrinol Metab. 2012 Aug 01; 303(3):E352-64. PMID: 22649066; PMCID: PMC3423121.
    54. Choudhury M, Friedman JE. Epigenetics and microRNAs in preeclampsia. Clin Exp Hypertens. 2012; 34(5):334-41. PMID: 22468840; PMCID: PMC3399917.
    55. Barbour LA, Van Pelt RE, Brumbaugh DE, Hernandez TL, Friedman JE. Comment on: Rowan et al. Metformin in Gestational diabetes: The Offspring Follow-Up (MiG TOFU): body composition at 2 years of age. Diabetes Care 2011;34:2279-2284. Diabetes Care. 2012 Mar; 35(3):e28; author reply e30. PMID: 22355031; PMCID: PMC3322686.
    56. Hernandez TL, Friedman JE, Van Pelt RE, Barbour LA. Patterns of glycemia in normal pregnancy: should the current therapeutic targets be challenged? Diabetes Care. 2011 Jul; 34(7):1660-8. PMID: 21709299; PMCID: PMC3120213.
    57. Choudhury M, Friedman JE. Obesity: childhood obesity--methylate now, pay later? Nat Rev Endocrinol. 2011 Jun 21; 7(8):439-40. PMID: 21691305.
      View in: PubMed
    58. Attia RR, Sharma P, Janssen RC, Friedman JE, Deng X, Lee JS, Elam MB, Cook GA, Park EA. Regulation of pyruvate dehydrogenase kinase 4 (PDK4) by CCAAT/enhancer-binding protein beta (C/EBPbeta). J Biol Chem. 2011 Jul 08; 286(27):23799-807. PMID: 21586575; PMCID: PMC3129161.
    59. Grant WF, Gillingham MB, Batra AK, Fewkes NM, Comstock SM, Takahashi D, Braun TP, Grove KL, Friedman JE, Marks DL. Maternal high fat diet is associated with decreased plasma n-3 fatty acids and fetal hepatic apoptosis in nonhuman primates. PLoS One. 2011 Feb 25; 6(2):e17261. PMID: 21364873; PMCID: PMC3045408.
    60. Barbour LA, McCurdy CE, Hernandez TL, Friedman JE. Chronically increased S6K1 is associated with impaired IRS1 signaling in skeletal muscle of GDM women with impaired glucose tolerance postpartum. J Clin Endocrinol Metab. 2011 May; 96(5):1431-41. PMID: 21289241; PMCID: PMC3085211.
    61. Choudhury M, Jonscher KR, Friedman JE. Reduced mitochondrial function in obesity-associated fatty liver: SIRT3 takes on the fat. Aging (Albany NY). 2011 Feb; 3(2):175-8. PMID: 21386135; PMCID: PMC3082013.
    62. Kendrick AA, Choudhury M, Rahman SM, McCurdy CE, Friederich M, Van Hove JL, Watson PA, Birdsey N, Bao J, Gius D, Sack MN, Jing E, Kahn CR, Friedman JE, Jonscher KR. Fatty liver is associated with reduced SIRT3 activity and mitochondrial protein hyperacetylation. Biochem J. 2011 Feb 01; 433(3):505-14. PMID: 21044047; PMCID: PMC3398511.
    63. Choudhury M, Qadri I, Rahman SM, Schroeder-Gloeckler J, Janssen RC, Friedman JE. C/EBPß is AMP kinase sensitive and up-regulates PEPCK in response to ER stress in hepatoma cells. Mol Cell Endocrinol. 2011 Jan 01; 331(1):102-8. PMID: 20797423; PMCID: PMC2981635.
    64. Majka SM, Fox KE, Psilas JC, Helm KM, Childs CR, Acosta AS, Janssen RC, Friedman JE, Woessner BT, Shade TR, Varella-Garcia M, Klemm DJ. De novo generation of white adipocytes from the myeloid lineage via mesenchymal intermediates is age, adipose depot, and gender specific. Proc Natl Acad Sci U S A. 2010 Aug 17; 107(33):14781-6. PMID: 20679227; PMCID: PMC2930432.
    65. Heerwagen MJ, Miller MR, Barbour LA, Friedman JE. Maternal obesity and fetal metabolic programming: a fertile epigenetic soil. Am J Physiol Regul Integr Comp Physiol. 2010 Sep; 299(3):R711-22. PMID: 20631295; PMCID: PMC2944425.
    66. Payne VA, Au WS, Lowe CE, Rahman SM, Friedman JE, O'Rahilly S, Rochford JJ. C/EBP transcription factors regulate SREBP1c gene expression during adipogenesis. Biochem J. 2009 Dec 14; 425(1):215-23. PMID: 19811452; PMCID: PMC2913385.
    67. Moriarty MW, McCurdy CE, Janssen RC, Shaw T, Leitner JW, Friedman JE, Draznin B. In vivo knockdown of p85alpha with an antisense oligonucleotide improves insulin sensitivity in Lep(ob/ob) and diet-induced obese mice. Horm Metab Res. 2009 Oct; 41(10):757-61. PMID: 19598077.
      View in: PubMed
    68. Rahman SM, Qadri I, Janssen RC, Friedman JE. Fenofibrate and PBA prevent fatty acid-induced loss of adiponectin receptor and pAMPK in human hepatoma cells and in hepatitis C virus-induced steatosis. J Lipid Res. 2009 Nov; 50(11):2193-202. PMID: 19502591; PMCID: PMC2759825.
    69. Thorn SR, Regnault TR, Brown LD, Rozance PJ, Keng J, Roper M, Wilkening RB, Hay WW, Friedman JE. Intrauterine growth restriction increases fetal hepatic gluconeogenic capacity and reduces messenger ribonucleic acid translation initiation and nutrient sensing in fetal liver and skeletal muscle. Endocrinology. 2009 Jul; 150(7):3021-30. PMID: 19342452; PMCID: PMC2703533.
    70. McCurdy CE, Bishop JM, Williams SM, Grayson BE, Smith MS, Friedman JE, Grove KL. Maternal high-fat diet triggers lipotoxicity in the fetal livers of nonhuman primates. J Clin Invest. 2009 Feb; 119(2):323-35. PMID: 19147984; PMCID: PMC2631287.
    71. Fox KE, Colton LA, Erickson PF, Friedman JE, Cha HC, Keller P, MacDougald OA, Klemm DJ. Regulation of cyclin D1 and Wnt10b gene expression by cAMP-responsive element-binding protein during early adipogenesis involves differential promoter methylation. J Biol Chem. 2008 Dec 12; 283(50):35096-105. PMID: 18957421; PMCID: PMC2596384.
    72. Wang H, Knaub LA, Jensen DR, Young Jung D, Hong EG, Ko HJ, Coates AM, Goldberg IJ, de la Houssaye BA, Janssen RC, McCurdy CE, Rahman SM, Soo Choi C, Shulman GI, Kim JK, Friedman JE, Eckel RH. Skeletal muscle-specific deletion of lipoprotein lipase enhances insulin signaling in skeletal muscle but causes insulin resistance in liver and other tissues. Diabetes. 2009 Jan; 58(1):116-24. PMID: 18952837; PMCID: PMC2606858.
    73. Brown LD, Rozance PJ, Barry JS, Friedman JE, Hay WW. Insulin is required for amino acid stimulation of dual pathways for translational control in skeletal muscle in the late-gestation ovine fetus. Am J Physiol Endocrinol Metab. 2009 Jan; 296(1):E56-63. PMID: 18940943; PMCID: PMC2636989.
    74. Sheikh MY, Choi J, Qadri I, Friedman JE, Sanyal AJ. Hepatitis C virus infection: molecular pathways to metabolic syndrome. Hepatology. 2008 Jun; 47(6):2127-33. PMID: 18446789.
      View in: PubMed
    75. Friedman JE, Kirwan JP, Jing M, Presley L, Catalano PM. Increased skeletal muscle tumor necrosis factor-alpha and impaired insulin signaling persist in obese women with gestational diabetes mellitus 1 year postpartum. Diabetes. 2008 Mar; 57(3):606-13. PMID: 18083784; PMCID: PMC4697130.
    76. Rozance PJ, Limesand SW, Barry JS, Brown LD, Thorn SR, LoTurco D, Regnault TR, Friedman JE, Hay WW. Chronic late-gestation hypoglycemia upregulates hepatic PEPCK associated with increased PGC1alpha mRNA and phosphorylated CREB in fetal sheep. Am J Physiol Endocrinol Metab. 2008 Feb; 294(2):E365-70. PMID: 18056789; PMCID: PMC3857025.
    77. Barbour LA, McCurdy CE, Hernandez TL, Kirwan JP, Catalano PM, Friedman JE. Cellular mechanisms for insulin resistance in normal pregnancy and gestational diabetes. Diabetes Care. 2007 Jul; 30 Suppl 2:S112-9. PMID: 17596458.
      View in: PubMed
    78. Payne VA, Au WS, Gray SL, Nora ED, Rahman SM, Sanders R, Hadaschik D, Friedman JE, O'rahilly S, Rochford JJ. Sequential regulation of diacylglycerol acyltransferase 2 expression by CAAT/enhancer-binding protein beta (C/EBPbeta) and C/EBPalpha during adipogenesis. J Biol Chem. 2007 Jul 20; 282(29):21005-14. PMID: 17504763; PMCID: PMC2254492.
    79. Rahman SM, Schroeder-Gloeckler JM, Janssen RC, Jiang H, Qadri I, Maclean KN, Friedman JE. CCAAT/enhancing binding protein beta deletion in mice attenuates inflammation, endoplasmic reticulum stress, and lipid accumulation in diet-induced nonalcoholic steatohepatitis. Hepatology. 2007 May; 45(5):1108-17. PMID: 17464987.
      View in: PubMed
    80. Schroeder-Gloeckler JM, Rahman SM, Janssen RC, Qiao L, Shao J, Roper M, Fischer SJ, Lowe E, Orlicky DJ, McManaman JL, Palmer C, Gitomer WL, Huang W, O'Doherty RM, Becker TC, Klemm DJ, Jensen DR, Pulawa LK, Eckel RH, Friedman JE. CCAAT/enhancer-binding protein beta deletion reduces adiposity, hepatic steatosis, and diabetes in Lepr(db/db) mice. J Biol Chem. 2007 May 25; 282(21):15717-29. PMID: 17387171; PMCID: PMC4109269.
    81. del Rincon JP, Iida K, Gaylinn BD, McCurdy CE, Leitner JW, Barbour LA, Kopchick JJ, Friedman JE, Draznin B, Thorner MO. Growth hormone regulation of p85alpha expression and phosphoinositide 3-kinase activity in adipose tissue: mechanism for growth hormone-mediated insulin resistance. Diabetes. 2007 Jun; 56(6):1638-46. PMID: 17363744.
      View in: PubMed
    82. McCurdy CE, Friedman JE. Early foetal programming of hepatic gluconeogenesis: Glucocorticoids strike back. Diabetologia. 2006 Jun; 49(6):1138-41. PMID: 16680490.
      View in: PubMed
    83. Barry JS, Davidsen ML, Limesand SW, Galan HL, Friedman JE, Regnault TR, Hay WW. Developmental changes in ovine myocardial glucose transporters and insulin signaling following hyperthermia-induced intrauterine fetal growth restriction. Exp Biol Med (Maywood). 2006 May; 231(5):566-75. PMID: 16636305.
      View in: PubMed
    84. Barbour LA, Mizanoor Rahman S, Gurevich I, Leitner JW, Fischer SJ, Roper MD, Knotts TA, Vo Y, McCurdy CE, Yakar S, Leroith D, Kahn CR, Cantley LC, Friedman JE, Draznin B. Increased P85alpha is a potent negative regulator of skeletal muscle insulin signaling and induces in vivo insulin resistance associated with growth hormone excess. J Biol Chem. 2005 Nov 11; 280(45):37489-94. PMID: 16166093.
      View in: PubMed
    85. Qiao L, Maclean PS, Schaack J, Orlicky DJ, Darimont C, Pagliassotti M, Friedman JE, Shao J. C/EBPalpha regulates human adiponectin gene transcription through an intronic enhancer. Diabetes. 2005 Jun; 54(6):1744-54. PMID: 15919796.
      View in: PubMed
    86. Velliquette RA, Friedman JE, Shao J, Zhang BB, Ernsberger P. Therapeutic actions of an insulin receptor activator and a novel peroxisome proliferator-activated receptor gamma agonist in the spontaneously hypertensive obese rat model of metabolic syndrome X. J Pharmacol Exp Ther. 2005 Jul; 314(1):422-30. PMID: 15833894.
      View in: PubMed
    87. Regnault TR, Friedman JE, Wilkening RB, Anthony RV, Hay WW. Fetoplacental transport and utilization of amino acids in IUGR--a review. Placenta. 2005 Apr; 26 Suppl A:S52-62. PMID: 15837069.
      View in: PubMed
    88. Shao J, Qiao L, Janssen RC, Pagliassotti M, Friedman JE. Chronic hyperglycemia enhances PEPCK gene expression and hepatocellular glucose production via elevated liver activating protein/liver inhibitory protein ratio. Diabetes. 2005 Apr; 54(4):976-84. PMID: 15793235.
      View in: PubMed
    89. Anderson MS, Thamotharan M, Kao D, Devaskar SU, Qiao L, Friedman JE, Hay WW. Effects of acute hyperinsulinemia on insulin signal transduction and glucose transporters in ovine fetal skeletal muscle. Am J Physiol Regul Integr Comp Physiol. 2005 Feb; 288(2):R473-81. PMID: 15539611.
      View in: PubMed
    90. Kirwan JP, Varastehpour A, Jing M, Presley L, Shao J, Friedman JE, Catalano PM. Reversal of insulin resistance postpartum is linked to enhanced skeletal muscle insulin signaling. J Clin Endocrinol Metab. 2004 Sep; 89(9):4678-84. PMID: 15356080.
      View in: PubMed
    91. Barbour LA, Shao J, Qiao L, Leitner W, Anderson M, Friedman JE, Draznin B. Human placental growth hormone increases expression of the p85 regulatory unit of phosphatidylinositol 3-kinase and triggers severe insulin resistance in skeletal muscle. Endocrinology. 2004 Mar; 145(3):1144-50. PMID: 14633976.
      View in: PubMed
    92. Shao J, Qiao L, Friedman JE. Prolactin, progesterone, and dexamethasone coordinately and adversely regulate glucokinase and cAMP/PDE cascades in MIN6 beta-cells. Am J Physiol Endocrinol Metab. 2004 Feb; 286(2):E304-10. PMID: 14559722.
      View in: PubMed
    93. Yamashita H, Shao J, Qiao L, Pagliassotti M, Friedman JE. Effect of spontaneous gestational diabetes on fetal and postnatal hepatic insulin resistance in Lepr(db/+) mice. Pediatr Res. 2003 Mar; 53(3):411-8. PMID: 12595588.
      View in: PubMed
    94. Kirwan JP, Hauguel-De Mouzon S, Lepercq J, Challier JC, Huston-Presley L, Friedman JE, Kalhan SC, Catalano PM. TNF-alpha is a predictor of insulin resistance in human pregnancy. Diabetes. 2002 Jul; 51(7):2207-13. PMID: 12086951.
      View in: PubMed
    95. Sun Y, Liu S, Ferguson S, Wang L, Klepcyk P, Yun JS, Friedman JE. Phosphoenolpyruvate carboxykinase overexpression selectively attenuates insulin signaling and hepatic insulin sensitivity in transgenic mice. J Biol Chem. 2002 Jun 28; 277(26):23301-7. PMID: 11964395.
      View in: PubMed
    96. Catalano PM, Nizielski SE, Shao J, Preston L, Qiao L, Friedman JE. Downregulated IRS-1 and PPARgamma in obese women with gestational diabetes: relationship to FFA during pregnancy. Am J Physiol Endocrinol Metab. 2002 Mar; 282(3):E522-33. PMID: 11832353.
      View in: PubMed
    97. Barbour LA, Shao J, Qiao L, Pulawa LK, Jensen DR, Bartke A, Garrity M, Draznin B, Friedman JE. Human placental growth hormone causes severe insulin resistance in transgenic mice. Am J Obstet Gynecol. 2002 Mar; 186(3):512-7. PMID: 11904616.
      View in: PubMed
    98. Shao J, Yamashita H, Qiao L, Draznin B, Friedman JE. Phosphatidylinositol 3-kinase redistribution is associated with skeletal muscle insulin resistance in gestational diabetes mellitus. Diabetes. 2002 Jan; 51(1):19-29. PMID: 11756318.
      View in: PubMed
    99. Friedman JE. Yeast-worm-animal similarities in insulin-like receptors and signal transduction: the aging pathway goes through insulin signaling. Pediatr Res. 2001 Sep; 50(3):308. PMID: 11518814.
      View in: PubMed
    100. Yamashita H, Shao J, Ishizuka T, Klepcyk PJ, Muhlenkamp P, Qiao L, Hoggard N, Friedman JE. Leptin administration prevents spontaneous gestational diabetes in heterozygous Lepr(db/+) mice: effects on placental leptin and fetal growth. Endocrinology. 2001 Jul; 142(7):2888-97. PMID: 11416008.
      View in: PubMed
    101. Yamashita H, Shao J, Ishizuka T, Klepcyk PJ, Muhlenkamp P, Qiao L, Hoggard N, Friedman JE. Leptin Administration Prevents Spontaneous Gestational Diabetes in Heterozygous Leprdb/+ Mice: Effects on Placental Leptin and Fetal Growth. Endocrinology. 2001 Jul 01; 142(7):2888-2897. PMID: 28201338.
      View in: PubMed
    102. Croniger CM, Millward C, Yang J, Kawai Y, Arinze IJ, Liu S, Harada-Shiba M, Chakravarty K, Friedman JE, Poli V, Hanson RW. Mice with a deletion in the gene for CCAAT/enhancer-binding protein beta have an attenuated response to cAMP and impaired carbohydrate metabolism. J Biol Chem. 2001 Jan 05; 276(1):629-38. PMID: 11024029.
      View in: PubMed
    103. Shao J, Catalano PM, Yamashita H, Ishizuka T, Friedman JE. Vanadate enhances but does not normalize glucose transport and insulin receptor phosphorylation in skeletal muscle from obese women with gestational diabetes mellitus. Am J Obstet Gynecol. 2000 Nov; 183(5):1263-70. PMID: 11084576.
      View in: PubMed
    104. Shao J, Yamashita H, Qiao L, Friedman JE. Decreased Akt kinase activity and insulin resistance in C57BL/KsJ-Leprdb/db mice. J Endocrinol. 2000 Oct; 167(1):107-15. PMID: 11018758.
      View in: PubMed
    105. Wang L, Shao J, Muhlenkamp P, Liu S, Klepcyk P, Ren J, Friedman JE. Increased insulin receptor substrate-1 and enhanced skeletal muscle insulin sensitivity in mice lacking CCAAT/enhancer-binding protein beta. J Biol Chem. 2000 May 12; 275(19):14173-81. PMID: 10747954.
      View in: PubMed
    106. Shao J, Catalano PM, Yamashita H, Ruyter I, Smith S, Youngren J, Friedman JE. Decreased insulin receptor tyrosine kinase activity and plasma cell membrane glycoprotein-1 overexpression in skeletal muscle from obese women with gestational diabetes mellitus (GDM): evidence for increased serine/threonine phosphorylation in pregnancy and GDM. Diabetes. 2000 Apr; 49(4):603-10. PMID: 10871198.
      View in: PubMed
    107. Yamashita H, Shao J, Friedman JE. Physiologic and molecular alterations in carbohydrate metabolism during pregnancy and gestational diabetes mellitus. Clin Obstet Gynecol. 2000 Mar; 43(1):87-98. PMID: 10694991.
      View in: PubMed
    108. Ernsberger P, Koletsky RJ, Friedman JE. Molecular pathology in the obese spontaneous hypertensive Koletsky rat: a model of syndrome X. Ann N Y Acad Sci. 1999 Nov 18; 892:272-88. PMID: 10842668.
      View in: PubMed
    109. Ernsberger P, Koletsky RJ, Kline DD, Bedol DM, Friedman JE. The SHROB model of syndrome X: effects of excess dietary sucrose. Ann N Y Acad Sci. 1999 Nov 18; 892:315-8. PMID: 10842673.
      View in: PubMed
    110. Friedman JE, Ishizuka T, Shao J, Huston L, Highman T, Catalano P. Impaired glucose transport and insulin receptor tyrosine phosphorylation in skeletal muscle from obese women with gestational diabetes. Diabetes. 1999 Sep; 48(9):1807-14. PMID: 10480612.
      View in: PubMed
    111. Arizmendi C, Liu S, Croniger C, Poli V, Friedman JE. The transcription factor CCAAT/enhancer-binding protein beta regulates gluconeogenesis and phosphoenolpyruvate carboxykinase (GTP) gene transcription during diabetes. J Biol Chem. 1999 May 07; 274(19):13033-40. PMID: 10224054.
      View in: PubMed
    112. Ishizuka T, Klepcyk P, Liu S, Panko L, Liu S, Gibbs EM, Friedman JE. Effects of overexpression of human GLUT4 gene on maternal diabetes and fetal growth in spontaneous gestational diabetic C57BLKS/J Lepr(db/+) mice. Diabetes. 1999 May; 48(5):1061-9. PMID: 10331411.
      View in: PubMed
    113. Ernsberger P, Ishizuka T, Liu S, Farrell CJ, Bedol D, Koletsky RJ, Friedman JE. Mechanisms of antihyperglycemic effects of moxonidine in the obese spontaneously hypertensive Koletsky rat (SHROB). J Pharmacol Exp Ther. 1999 Jan; 288(1):139-47. PMID: 9862764.
      View in: PubMed
    114. Liu S, Croniger C, Arizmendi C, Harada-Shiba M, Ren J, Poli V, Hanson RW, Friedman JE. Hypoglycemia and impaired hepatic glucose production in mice with a deletion of the C/EBPbeta gene. J Clin Invest. 1999 Jan; 103(2):207-13. PMID: 9916132; PMCID: PMC407878.
    115. Ishizuka T, Ernsberger P, Liu S, Bedol D, Lehman TM, Koletsky RJ, Friedman JE. Phenotypic consequences of a nonsense mutation in the leptin receptor gene (fak) in obese spontaneously hypertensive Koletsky rats (SHROB). J Nutr. 1998 Dec; 128(12):2299-306. PMID: 9868173.
      View in: PubMed
    116. Highman TJ, Friedman JE, Huston LP, Wong WW, Catalano PM. Longitudinal changes in maternal serum leptin concentrations, body composition, and resting metabolic rate in pregnancy. Am J Obstet Gynecol. 1998 May; 178(5):1010-5. PMID: 9609576.
      View in: PubMed
    117. Friedman JE, Sun Y, Ishizuka T, Farrell CJ, McCormack SE, Herron LM, Hakimi P, Lechner P, Yun JS. Phosphoenolpyruvate carboxykinase (GTP) gene transcription and hyperglycemia are regulated by glucocorticoids in genetically obese db/db transgenic mice. J Biol Chem. 1997 Dec 12; 272(50):31475-81. PMID: 9395482.
      View in: PubMed
    118. Friedman JE, Ferrara CM, Aulak KS, Hatzoglou M, McCune SA, Park S, Sherman WM. Exercise training down-regulates ob gene expression in the genetically obese SHHF/Mcc-fa(cp) rat. Horm Metab Res. 1997 May; 29(5):214-9. PMID: 9228205.
      View in: PubMed
    119. Horn DB, Podolin DA, Friedman JE, Scholnick DA, Mazzeo RS. Alterations in key gluconeogenic regulators with age and endurance training. Metabolism. 1997 Apr; 46(4):414-9. PMID: 9109846.
      View in: PubMed
    120. Nizielski SE, Arizmendi C, Shteyngarts AR, Farrell CJ, Friedman JE. Involvement of transcription factor C/EBP-beta in stimulation of PEPCK gene expression during exercise. Am J Physiol. 1996 May; 270(5 Pt 2):R1005-12. PMID: 8928898.
      View in: PubMed
    121. Friedman JE, Caro JF, Pories WJ, Azevedo JL, Dohm GL. Glucose metabolism in incubated human muscle: effect of obesity and non-insulin-dependent diabetes mellitus. Metabolism. 1994 Aug; 43(8):1047-54. PMID: 8052146.
      View in: PubMed
    122. Friedman JE. Role of glucocorticoids in activation of hepatic PEPCK gene transcription during exercise. Am J Physiol. 1994 Apr; 266(4 Pt 1):E560-6. PMID: 8178976.
      View in: PubMed
    123. Friedman JE, Yun JS, Patel YM, McGrane MM, Hanson RW. Glucocorticoids regulate the induction of phosphoenolpyruvate carboxykinase (GTP) gene transcription during diabetes. J Biol Chem. 1993 Jun 15; 268(17):12952-7. PMID: 7685354.
      View in: PubMed
    124. Sherman WM, Friedman JE, Gao JP, Reed MJ, Elton CW, Dohm GL. Glycemia and exercise training alter glucose transport and GLUT4 in the Zucker rat. Med Sci Sports Exerc. 1993 Mar; 25(3):341-8. PMID: 8455449.
      View in: PubMed
    125. Friedman JE, Dohm GL, Leggett-Frazier N, Elton CW, Tapscott EB, Pories WP, Caro JF. Restoration of insulin responsiveness in skeletal muscle of morbidly obese patients after weight loss. Effect on muscle glucose transport and glucose transporter GLUT4. J Clin Invest. 1992 Feb; 89(2):701-5. PMID: 1737857; PMCID: PMC442905.
    126. Houmard JA, Egan PC, Neufer PD, Friedman JE, Wheeler WS, Israel RG, Dohm GL. Elevated skeletal muscle glucose transporter levels in exercise-trained middle-aged men. Am J Physiol. 1991 Oct; 261(4 Pt 1):E437-43. PMID: 1928336.
      View in: PubMed
    127. Friedman JE, Dohm GL, Elton CW, Rovira A, Chen JJ, Leggett-Frazier N, Atkinson SM, Thomas FT, Long SD, Caro JF. Muscle insulin resistance in uremic humans: glucose transport, glucose transporters, and insulin receptors. Am J Physiol. 1991 Jul; 261(1 Pt 1):E87-94. PMID: 1858877.
      View in: PubMed
    128. Friedman JE, Dudek RW, Whitehead DS, Downes DL, Frisell WR, Caro JF, Dohm GL. Immunolocalization of glucose transporter GLUT4 within human skeletal muscle. Diabetes. 1991 Jan; 40(1):150-4. PMID: 2015971.
      View in: PubMed
    129. Friedman JE, Lemon PW, Finkelstein JA. Effect of exercise and obesity on skeletal muscle amino acid uptake. J Appl Physiol (1985). 1990 Oct; 69(4):1347-52. PMID: 2262452.
      View in: PubMed
    130. Kern M, Wells JA, Stephens JM, Elton CW, Friedman JE, Tapscott EB, Pekala PH, Dohm GL. Insulin responsiveness in skeletal muscle is determined by glucose transporter (Glut4) protein level. Biochem J. 1990 Sep 01; 270(2):397-400. PMID: 2205203; PMCID: PMC1131735.
    131. Friedman JE, Sherman WM, Reed MJ, Elton CW, Dohm GL. Exercise training increases glucose transporter protein GLUT-4 in skeletal muscle of obese Zucker (fa/fa) rats. FEBS Lett. 1990 Jul 30; 268(1):13-6. PMID: 2200706.
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