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Chrystelle Valerie Garat-Carter

TitleAssoc Professor-Research
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus

    Collapse Research 
    Collapse research activities and funding
    R01HL064919     (GARAT-CARTER, CHRYSTELLE V)Aug 1, 2001 - Jul 31, 2008
    Regulation of Pulmonary Vascular Tone During Cirrhosis
    Role: Principal Investigator

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Geary K, Knaub LA, Schauer IE, Keller AC, Watson PA, Miller MW, Garat CV, Nadeau KJ, Cree-Green M, Pugazhenthi S, Regensteiner JG, Klemm DJ, Reusch JE. Targeting mitochondria to restore failed adaptation to exercise in diabetes. Biochem Soc Trans. 2014 Apr; 42(2):231-8. PMID: 24646223; PMCID: PMC4103429.
    2. Garat CV, Crossno JT, Sullivan TM, Reusch JE, Klemm DJ. Inhibition of phosphatidylinositol 3-kinase/Akt signaling attenuates hypoxia-induced pulmonary artery remodeling and suppresses CREB depletion in arterial smooth muscle cells. J Cardiovasc Pharmacol. 2013 Dec; 62(6):539-48. PMID: 24084215; PMCID: PMC4143163.
    3. Jun D, Garat C, West J, Thorn N, Chow K, Cleaver T, Sullivan T, Torchia EC, Childs C, Shade T, Tadjali M, Lara A, Nozik-Grayck E, Malkoski S, Sorrentino B, Meyrick B, Klemm D, Rojas M, Wagner DH, Majka SM. The pathology of bleomycin-induced fibrosis is associated with loss of resident lung mesenchymal stem cells that regulate effector T-cell proliferation. Stem Cells. 2011 Apr; 29(4):725-35. PMID: 21312316.
      View in: PubMed
    4. Garat CV, Crossno JT, Sullivan TM, Reusch JE, Klemm DJ. Thiazolidinediones prevent PDGF-BB-induced CREB depletion in pulmonary artery smooth muscle cells by preventing upregulation of casein kinase 2 alpha' catalytic subunit. J Cardiovasc Pharmacol. 2010 May; 55(5):469-80. PMID: 20147842; PMCID: PMC2874608.
    5. Bhattacharjee R, Li T, Koshy S, Beard LL, Sharma K, Carter EP, Garat C, Folkesson HG. Stimulation of MAP kinase pathways after maternal IL-1beta exposure induces fetal lung fluid absorption in guinea pigs. Respir Res. 2007 Mar 26; 8:27. PMID: 17386088; PMCID: PMC1847817.
    6. Crossno JT, Garat CV, Reusch JE, Morris KG, Dempsey EC, McMurtry IF, Stenmark KR, Klemm DJ. Rosiglitazone attenuates hypoxia-induced pulmonary arterial remodeling. Am J Physiol Lung Cell Mol Physiol. 2007 Apr; 292(4):L885-97. PMID: 17189321.
      View in: PubMed
    7. Garat CV, Fankell D, Erickson PF, Reusch JE, Bauer NN, McMurtry IF, Klemm DJ. Platelet-derived growth factor BB induces nuclear export and proteasomal degradation of CREB via phosphatidylinositol 3-kinase/Akt signaling in pulmonary artery smooth muscle cells. Mol Cell Biol. 2006 Jul; 26(13):4934-48. PMID: 16782881; PMCID: PMC1489168.
    8. Imamura M, Luo B, Limbird J, Vitello A, Oka M, Ivy DD, McMurtry IF, Garat CV, Fallon MB, Carter EP. Hypoxic pulmonary hypertension is prevented in rats with common bile duct ligation. J Appl Physiol (1985). 2005 Feb; 98(2):739-47. PMID: 15516365.
      View in: PubMed
    9. Carter EP, Garat C, Imamura M. Continual emerging roles of HO-1: protection against airway inflammation. Am J Physiol Lung Cell Mol Physiol. 2004 Jul; 287(1):L24-5. PMID: 15187007.
      View in: PubMed
    10. Kaplan-Albuquerque N, Garat C, Desseva C, Jones PL, Nemenoff RA. Platelet-derived growth factor-BB-mediated activation of Akt suppresses smooth muscle-specific gene expression through inhibition of mitogen-activated protein kinase and redistribution of serum response factor. J Biol Chem. 2003 Oct 10; 278(41):39830-8. PMID: 12882977.
      View in: PubMed
    11. Garat C, Arend WP. Intracellular IL-1Ra type 1 inhibits IL-1-induced IL-6 and IL-8 production in Caco-2 intestinal epithelial cells through inhibition of p38 mitogen-activated protein kinase and NF-kappaB pathways. Cytokine. 2003 Jul; 23(1-2):31-40. PMID: 12901852.
      View in: PubMed
    12. Kaplan-Albuquerque N, Garat C, Van Putten V, Nemenoff RA. Regulation of SM22 alpha expression by arginine vasopressin and PDGF-BB in vascular smooth muscle cells. Am J Physiol Heart Circ Physiol. 2003 Oct; 285(4):H1444-52. PMID: 12829429.
      View in: PubMed
    13. Miyazono M, Garat C, Morris KG, Carter EP. Decreased renal heme oxygenase-1 expression contributes to decreased renal function during cirrhosis. Am J Physiol Renal Physiol. 2002 Nov; 283(5):F1123-31. PMID: 12372789.
      View in: PubMed
    14. Garat C, Van Putten V, Refaat ZA, Dessev C, Han SY, Nemenoff RA. Induction of smooth muscle alpha-actin in vascular smooth muscle cells by arginine vasopressin is mediated by c-Jun amino-terminal kinases and p38 mitogen-activated protein kinase. J Biol Chem. 2000 Jul 21; 275(29):22537-43. PMID: 10807920.
      View in: PubMed
    15. Munger JS, Huang X, Kawakatsu H, Griffiths MJ, Dalton SL, Wu J, Pittet JF, Kaminski N, Garat C, Matthay MA, Rifkin DB, Sheppard D. The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis. Cell. 1999 Feb 05; 96(3):319-28. PMID: 10025398.
      View in: PubMed
    16. Garat C, Carter EP, Matthay MA. New in situ mouse model to quantify alveolar epithelial fluid clearance. J Appl Physiol (1985). 1998 May; 84(5):1763-7. PMID: 9572828.
      View in: PubMed
    17. Garat C, Jayr C, Eddahibi S, Laffon M, Meignan M, Adnot S. Effects of inhaled nitric oxide or inhibition of endogenous nitric oxide formation on hyperoxic lung injury. Am J Respir Crit Care Med. 1997 Jun; 155(6):1957-64. PMID: 9196102.
      View in: PubMed
    18. Oliver BL, Garat C, Pytela R, Matthay MA. Protein tyrosine phosphatases mediate cell readhesion in alveolar epithelial cells mechanically separated from in vitro matrix. Am J Respir Cell Mol Biol. 1997 May; 16(5):613-20. PMID: 9160844.
      View in: PubMed
    19. Garat C, Meignan M, Matthay MA, Luo DF, Jayr C. Alveolar epithelial fluid clearance mechanisms are intact after moderate hyperoxic lung injury in rats. Chest. 1997 May; 111(5):1381-8. PMID: 9149598.
      View in: PubMed
    20. Rezaiguia S, Garat C, Delclaux C, Meignan M, Fleury J, Legrand P, Matthay MA, Jayr C. Acute bacterial pneumonia in rats increases alveolar epithelial fluid clearance by a tumor necrosis factor-alpha-dependent mechanism. J Clin Invest. 1997 Jan 15; 99(2):325-35. PMID: 9006001; PMCID: PMC507800.
    21. Garat C, Kheradmand F, Albertine KH, Folkesson HG, Matthay MA. Soluble and insoluble fibronectin increases alveolar epithelial wound healing in vitro. Am J Physiol. 1996 Nov; 271(5 Pt 1):L844-53. PMID: 8944729.
      View in: PubMed
    22. Garat C, Rezaiguia S, Meignan M, D'Ortho MP, Harf A, Matthay MA, Jayr C. Alveolar endotoxin increases alveolar liquid clearance in rats. J Appl Physiol (1985). 1995 Dec; 79(6):2021-8. PMID: 8847269.
      View in: PubMed
    23. Jayr C, Garat C, Meignan M, Pittet JF, Zelter M, Matthay MA. Alveolar liquid and protein clearance in anesthetized ventilated rats. J Appl Physiol (1985). 1994 Jun; 76(6):2636-42. PMID: 7928894.
      View in: PubMed
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