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Kendall S Hunter

TitleAsst Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-PEDS
Phone303/724-4197
    Other Positions
    TitleAssociate Professor
    InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
    DepartmentENGR-Bioengineering


    Collapse Research 
    Collapse research activities and funding
    K25HL094749     (HUNTER, KENDALL STEPHEN)Aug 10, 2010 - May 31, 2015
    NIH/NHLBI
    Non-invasive Diagnostics and Outcomes Predictors in Pediatric PAH
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Schäfer M, Kheyfets VO, Barker AJ, Stenmark K, Hunter KS, McClatchey PM, Buckner JK, Reece TB, Jazaeri O, Fenster BE. Reduced shear stress and associated aortic deformation in the thoracic aorta of patients with chronic obstructive pulmonary disease. J Vasc Surg. 2017 Oct 03. PMID: 28986100.
      View in: PubMed
    2. Kheyfets VO, Sucharov CC, Truong U, Dunning J, Hunter K, Ivy D, Miyamoto S, Shandas R. Circulating miRNAs in Pediatric Pulmonary Hypertension Show Promise as Biomarkers of Vascular Function. Oxid Med Cell Longev. 2017; 2017:4957147. PMID: 28819545.
      View in: PubMed
    3. Newman JH, Rich S, Abman SH, Alexander JH, Barnard J, Beck GJ, Benza RL, Bull TM, Chan SY, Chun HJ, Doogan D, Dupuis J, Erzurum SC, Frantz RP, Geraci M, Gillies H, Gladwin M, Gray MP, Hemnes AR, Herbst RS, Hernandez AF, Hill NS, Horn EM, Hunter K, Jing ZC, Johns R, Kaul S, Kawut SM, Lahm T, Leopold JA, Lewis GD, Mathai SC, McLaughlin VV, Michelakis ED, Nathan SD, Nichols W, Page G, Rabinovitch M, Rich J, Rischard F, Rounds S, Shah SJ, Tapson VF, Lowy N, Stockbridge N, Weinmann G, Xiao L. Enhancing Insights into Pulmonary Vascular Disease through a Precision Medicine Approach. A Joint NHLBI-Cardiovascular Medical Research and Education Fund Workshop Report. Am J Respir Crit Care Med. 2017 Jun 15; 195(12):1661-1670. PMID: 28430547.
      View in: PubMed
    4. Schäfer M, Ivy DD, Barker AJ, Kheyfets V, Shandas R, Abman SH, Hunter KS, Truong U. Characterization of CMR-derived haemodynamic data in children with pulmonary arterial hypertension. Eur Heart J Cardiovasc Imaging. 2017 Apr 01; 18(4):424-431. PMID: 27444679.
      View in: PubMed
    5. Patel AC, Dodson RB, Cornwell WK, Hunter KS, Cleveland JC, Brieke A, Lindenfeld J, Ambardekar AV. Dynamic Changes in Aortic Vascular Stiffness in Patients Bridged to Transplant With Continuous-Flow Left Ventricular Assist Devices. JACC Heart Fail. 2017 Jun; 5(6):449-459. PMID: 28285118.
      View in: PubMed
    6. Schäfer M, Ivy DD, Abman SH, Barker AJ, Browne LP, Fonseca B, Kheyfets V, Hunter KS, Truong U. Apparent Aortic Stiffness in Children With Pulmonary Arterial Hypertension: Existence of Vascular Interdependency? Circ Cardiovasc Imaging. 2017 Feb; 10(2). PMID: 28193613.
      View in: PubMed
    7. Madhavan K, Frid MG, Hunter K, Shandas R, Stenmark KR, Park D. Development of an electrospun biomimetic polyurea scaffold suitable for vascular grafting. J Biomed Mater Res B Appl Biomater. 2017 Jan 27. PMID: 28130878.
      View in: PubMed
    8. Kheyfets VO, Dunning J, Truong U, Ivy D, Hunter K, Shandas R. A Zero-Dimensional Model and Protocol for Simulating Patient-Specific Pulmonary Hemodynamics From Limited Clinical Data. J Biomech Eng. 2016 Dec 01; 138(12). PMID: 27684888.
      View in: PubMed
    9. Vanderpool RR, Rischard F, Naeije R, Hunter K, Simon MA. Simple functional imaging of the right ventricle in pulmonary hypertension: Can right ventricular ejection fraction be improved? Int J Cardiol. 2016 Nov 15; 223:93-94. PMID: 27532240.
      View in: PubMed
    10. Jazaeri O, Magee G, Schaefer M, Volpe R, Rocker A, Arce R, Hunter KS. Usefulness of Four-Dimensional Flow Cardiac Magnetic Resonance for Evaluation of Aortic Dissection. J Vasc Surg. 2016 Aug; 64(2):552. PMID: 27763317.
      View in: PubMed
    11. Humphries SM, Hunter KS, Shandas R, Deterding RR, DeBoer EM. Erratum to: Analysis of pediatric airway morphology using statistical shape modeling. Med Biol Eng Comput. 2016 Jun; 54(6):913. PMID: 26815534.
      View in: PubMed
    12. Kheyfets VO, Schafer M, Podgorski CA, Schroeder JD, Browning J, Hertzberg J, Buckner JK, Hunter KS, Shandas R, Fenster BE. 4D magnetic resonance flow imaging for estimating pulmonary vascular resistance in pulmonary hypertension. J Magn Reson Imaging. 2016 Oct; 44(4):914-22. PMID: 27173445.
      View in: PubMed
    13. McClatchey PM, Schafer M, Hunter KS, Reusch JE. The endothelial glycocalyx promotes homogenous blood flow distribution within the microvasculature. Am J Physiol Heart Circ Physiol. 2016 Jul 01; 311(1):H168-76. PMID: 27199117.
      View in: PubMed
    14. Schäfer M, Kheyfets VO, Schroeder JD, Dunning J, Shandas R, Buckner JK, Browning J, Hertzberg J, Hunter KS, Fenster BE. Main pulmonary arterial wall shear stress correlates with invasive hemodynamics and stiffness in pulmonary hypertension. Pulm Circ. 2016 Mar; 6(1):37-45. PMID: 27076906; PMCID: PMC4809665.
    15. Schäfer M, Browning J, Schroeder JD, Shandas R, Kheyfets VO, Buckner JK, Hunter KS, Hertzberg JR, Fenster BE. Vorticity is a marker of diastolic ventricular interdependency in pulmonary hypertension. Pulm Circ. 2016 Mar; 6(1):46-54. PMID: 27162613; PMCID: PMC4860542.
    16. Schäfer M, Myers C, Brown RD, Frid MG, Tan W, Hunter K, Stenmark KR. Pulmonary Arterial Stiffness: Toward a New Paradigm in Pulmonary Arterial Hypertension Pathophysiology and Assessment. Curr Hypertens Rep. 2016 Jan; 18(1):4. PMID: 26733189.
      View in: PubMed
    17. Humphries SM, Hunter KS, Shandas R, Deterding RR, DeBoer EM. Analysis of pediatric airway morphology using statistical shape modeling. Med Biol Eng Comput. 2016 Jun; 54(6):899-911. PMID: 26718559.
      View in: PubMed
    18. Mandell E, Powers KN, Harral JW, Seedorf GJ, Hunter KS, Abman SH, Dodson RB. Intrauterine endotoxin-induced impairs pulmonary vascular function and right ventricular performance in infant rats and improvement with early vitamin D therapy. Am J Physiol Lung Cell Mol Physiol. 2015 Dec 15; 309(12):L1438-46. PMID: 26475735; PMCID: PMC4683312 [Available on 12/15/16].
    19. Truong U, Patel S, Kheyfets V, Dunning J, Fonseca B, Barker AJ, Ivy D, Shandas R, Hunter K. Non-invasive determination by cardiovascular magnetic resonance of right ventricular-vascular coupling in children and adolescents with pulmonary hypertension. J Cardiovasc Magn Reson. 2015 Sep 16; 17:81. PMID: 26376972; PMCID: PMC4574020.
    20. Di Maria MV, Burkett DA, Younoszai AK, Landeck BF, Mertens L, Ivy DD, Friedberg MK, Hunter KS. Echocardiographic estimation of right ventricular stroke work in children with pulmonary arterial hypertension: comparison with invasive measurements. J Am Soc Echocardiogr. 2015 Nov; 28(11):1350-7. PMID: 26299333.
      View in: PubMed
    21. Ambardekar AV, Hunter KS, Babu AN, Tuder RM, Dodson RB, Lindenfeld J. Changes in Aortic Wall Structure, Composition, and Stiffness With Continuous-Flow Left Ventricular Assist Devices: A Pilot Study. Circ Heart Fail. 2015 Sep; 8(5):944-52. PMID: 26136459.
      View in: PubMed
    22. Tan W, Madhavan K, Hunter KS, Park D, Stenmark KR. Vascular stiffening in pulmonary hypertension: cause or consequence? (2013 Grover Conference series). Pulm Circ. 2014 Dec; 4(4):560-80. PMID: 25610594; PMCID: PMC4278618.
    23. Dodson RB, Morgan MR, Galambos C, Hunter KS, Abman SH. Chronic intrauterine pulmonary hypertension increases main pulmonary artery stiffness and adventitial remodeling in fetal sheep. Am J Physiol Lung Cell Mol Physiol. 2014 Dec 01; 307(11):L822-8. PMID: 25326575; PMCID: PMC4254964.
    24. Schreier DA, Hacker TA, Hunter K, Eickoff J, Liu A, Song G, Chesler N. Impact of increased hematocrit on right ventricular afterload in response to chronic hypoxia. J Appl Physiol (1985). 2014 Oct 15; 117(8):833-9. PMID: 25170068; PMCID: PMC4199994.
    25. Tan Y, Tseng PO, Wang D, Zhang H, Hunter K, Hertzberg J, Stenmark KR, Tan W. Stiffening-induced high pulsatility flow activates endothelial inflammation via a TLR2/NF-?B pathway. PLoS One. 2014; 9(7):e102195. PMID: 25029271; PMCID: PMC4100881.
    26. Di Maria MV, Younoszai AK, Mertens L, Landeck BF, Ivy DD, Hunter KS, Friedberg MK. RV stroke work in children with pulmonary arterial hypertension: estimation based on invasive haemodynamic assessment and correlation with outcomes. Heart. 2014 Sep; 100(17):1342-7. PMID: 24780910.
      View in: PubMed
    27. Hunter KS, Fjield T, Heitzmann H, Shandas R, Kahook MY. Characterization of micro-invasive trabecular bypass stents by ex vivo perfusion and computational flow modeling. Clin Ophthalmol. 2014; 8:499-506. PMID: 24648713; PMCID: PMC3956696.
    28. Yunker BE, Dodd GD, Chen SJ, Chang S, Lanning CJ, Scherzinger AL, Shandas R, Feng Y, Hunter KS. The design and fabrication of two portal vein flow phantoms by different methods. Med Phys. 2014 Feb; 41(2):023701. PMID: 24506653; PMCID: PMC3986009.
    29. Dodson RB, Rozance PJ, Petrash CC, Hunter KS, Ferguson VL. Thoracic and abdominal aortas stiffen through unique extracellular matrix changes in intrauterine growth restricted fetal sheep. Am J Physiol Heart Circ Physiol. 2014 Feb; 306(3):H429-37. PMID: 24322609; PMCID: PMC3920138.
    30. Rogers NM, Yao M, Sembrat J, George MP, Knupp H, Ross M, Sharifi-Sanjani M, Milosevic J, St Croix C, Rajkumar R, Frid MG, Hunter KS, Mazzaro L, Novelli EM, Stenmark KR, Gladwin MT, Ahmad F, Champion HC, Isenberg JS. Cellular, pharmacological, and biophysical evaluation of explanted lungs from a patient with sickle cell disease and severe pulmonary arterial hypertension. Pulm Circ. 2013 Dec; 3(4):936-51. PMID: 25006410; PMCID: PMC4070844.
    31. Su Z, Tan W, Shandas R, Hunter KS. Influence of distal resistance and proximal stiffness on hemodynamics and RV afterload in progression and treatments of pulmonary hypertension: a computational study with validation using animal models. Comput Math Methods Med. 2013; 2013:618326. PMID: 24367392; PMCID: PMC3842075.
    32. Truong U, Fonseca B, Dunning J, Burgett S, Lanning C, Ivy DD, Shandas R, Hunter K, Barker AJ. Wall shear stress measured by phase contrast cardiovascular magnetic resonance in children and adolescents with pulmonary arterial hypertension. J Cardiovasc Magn Reson. 2013 Sep 13; 15:81. PMID: 24034144; PMCID: PMC3848825.
    33. Yunker BE, Cordes D, Scherzinger AL, Dodd GD, Shandas R, Feng Y, Hunter KS. An investigation of industrial molding compounds for use in 3D ultrasound, MRI, and CT imaging phantoms. Med Phys. 2013 May; 40(5):052905. PMID: 23635298; PMCID: PMC3651250.
    34. Dodson RB, Martin JT, Hunter KS, Ferguson VL. Determination of hyperelastic properties for umbilical artery in preeclampsia from uniaxial extension tests. Eur J Obstet Gynecol Reprod Biol. 2013 Jul; 169(2):207-12. PMID: 23548660; PMCID: PMC3750117.
    35. Dodson RB, Rozance PJ, Reina-Romo E, Ferguson VL, Hunter KS. Hyperelastic remodeling in the intrauterine growth restricted (IUGR) carotid artery in the near-term fetus. J Biomech. 2013 Mar 15; 46(5):956-63. PMID: 23332229; PMCID: PMC3742322.
    36. Mertens L, Hunter K. Imaging right ventricular shape and remodelling. Eur Heart J Cardiovasc Imaging. 2013 Apr; 14(4):311-2. PMID: 23235988.
      View in: PubMed
    37. Dodson RB, Rozance PJ, Fleenor BS, Petrash CC, Shoemaker LG, Hunter KS, Ferguson VL. Increased arterial stiffness and extracellular matrix reorganization in intrauterine growth-restricted fetal sheep. Pediatr Res. 2013 Feb; 73(2):147-54. PMID: 23154756; PMCID: PMC3742323.
    38. Reusser M, Hunter KS, Lammers SR, Stenmark KR. Validation of a pressure diameter method for determining modulus and strain of collagen engagement for long branches of bovine pulmonary arteries. J Biomech Eng. 2012 May; 134(5):054501. PMID: 22757496.
      View in: PubMed
    39. Scott-Drechsel D, Su Z, Hunter K, Li M, Shandas R, Tan W. A new flow co-culture system for studying mechanobiology effects of pulse flow waves. Cytotechnology. 2012 Dec; 64(6):649-66. PMID: 22526489; PMCID: PMC3488372.
    40. Tian L, Lammers SR, Kao PH, Albietz JA, Stenmark KR, Qi HJ, Shandas R, Hunter KS. Impact of residual stretch and remodeling on collagen engagement in healthy and pulmonary hypertensive calf pulmonary arteries at physiological pressures. Ann Biomed Eng. 2012 Jul; 40(7):1419-33. PMID: 22237861; PMCID: PMC3593651.
    41. Lammers S, Scott D, Hunter K, Tan W, Shandas R, Stenmark KR. Mechanics and function of the pulmonary vasculature: implications for pulmonary vascular disease and right ventricular function. Compr Physiol. 2012 Jan; 2(1):295-319. PMID: 23728987.
      View in: PubMed
    42. Lammers S, Scott D, Hunter K, Tan W, Shandas R, Stenmark KR. Mechanics and Function of the Pulmonary Vasculature: Implications for Pulmonary Vascular Disease and Right Ventricular Function. Compr Physiol. 2012 Jan 01; 2(1):295-319. PMID: 23487595.
      View in: PubMed
    43. Su Z, Hunter KS, Shandas R. Impact of pulmonary vascular stiffness and vasodilator treatment in pediatric pulmonary hypertension: 21 patient-specific fluid-structure interaction studies. Comput Methods Programs Biomed. 2012 Nov; 108(2):617-28. PMID: 21975085; PMCID: PMC3272113.
    44. Tian L, Lammers SR, Kao PH, Reusser M, Stenmark KR, Hunter KS, Qi HJ, Shandas R. Linked opening angle and histological and mechanical aspects of the proximal pulmonary arteries of healthy and pulmonary hypertensive rats and calves. Am J Physiol Heart Circ Physiol. 2011 Nov; 301(5):H1810-8. PMID: 21856906; PMCID: PMC3213979.
    45. Hunter KS, Lammers SR, Shandas R. Pulmonary vascular stiffness: measurement, modeling, and implications in normal and hypertensive pulmonary circulations. Compr Physiol. 2011 Jul; 1(3):1413-35. PMID: 23733649; PMCID: PMC4113421.
    46. Kao PH, Lammers SR, Tian L, Hunter K, Stenmark KR, Shandas R, Qi HJ. A microstructurally driven model for pulmonary artery tissue. J Biomech Eng. 2011 May; 133(5):051002. PMID: 21599093; PMCID: PMC3108498.
    47. Hunter KS, Feinstein JA, Ivy DD, Shandas R. Computational Simulation of the Pulmonary Arteries and its Role in the Study of Pediatric Pulmonary Hypertension. Prog Pediatr Cardiol. 2010 Dec 01; 30(1-2):63-69. PMID: 21499523.
      View in: PubMed
    48. Tian L, Hunter KS, Kirby KS, Ivy DD, Shandas R. Measurement uncertainty in pulmonary vascular input impedance and characteristic impedance estimated from pulsed-wave Doppler ultrasound and pressure: clinical studies on 57 pediatric patients. Physiol Meas. 2010 Jun; 31(6):729-48. PMID: 20410558; PMCID: PMC3010409.
    49. Kao PH, Lammers SR, Hunter K, Stenmark KR, Shandas R, Qi HJ. Constitutive Modeling of Anisotropic Finite-Deformation Hyperelastic Behaviors of Soft Materials Reinforced by Tortuous Fibers. Int J Struct Changes Sol. 2010 Apr; 2(1):19-29. PMID: 21822502.
      View in: PubMed
    50. Hunter KS, Albietz JA, Lee PF, Lanning CJ, Lammers SR, Hofmeister SH, Kao PH, Qi HJ, Stenmark KR, Shandas R. In vivo measurement of proximal pulmonary artery elastic modulus in the neonatal calf model of pulmonary hypertension: development and ex vivo validation. J Appl Physiol (1985). 2010 Apr; 108(4):968-75. PMID: 20093662; PMCID: PMC2853208.
    51. Chen J, Hunter KS, Shandas R. Wave scattering from encapsulated microbubbles subject to high-frequency ultrasound: contribution of higher-order scattering modes. J Acoust Soc Am. 2009 Oct; 126(4):1766-75. PMID: 19813791; PMCID: PMC2771053.
    52. Lammers SR, Kao PH, Qi HJ, Hunter K, Lanning C, Albietz J, Hofmeister S, Mecham R, Stenmark KR, Shandas R. Changes in the structure-function relationship of elastin and its impact on the proximal pulmonary arterial mechanics of hypertensive calves. Am J Physiol Heart Circ Physiol. 2008 Oct; 295(4):H1451-9. PMID: 18660454; PMCID: PMC2593497.
    53. Hunter KS, Gross JK, Lanning CJ, Kirby KS, Dyer KL, Ivy DD, Shandas R. Noninvasive methods for determining pulmonary vascular function in children with pulmonary arterial hypertension: application of a mechanical oscillator model. Congenit Heart Dis. 2008 Mar-Apr; 3(2):106-16. PMID: 18380759; PMCID: PMC3116924.
    54. Hunter KS, Lee PF, Lanning CJ, Ivy DD, Kirby KS, Claussen LR, Chan KC, Shandas R. Pulmonary vascular input impedance is a combined measure of pulmonary vascular resistance and stiffness and predicts clinical outcomes better than pulmonary vascular resistance alone in pediatric patients with pulmonary hypertension. Am Heart J. 2008 Jan; 155(1):166-74. PMID: 18082509; PMCID: PMC3139982.
    55. Zhang Y, Dunn ML, Hunter KS, Lanning C, Ivy DD, Claussen L, Chen SJ, Shandas R. Application of a microstructural constitutive model of the pulmonary artery to patient-specific studies: validation and effect of orthotropy. J Biomech Eng. 2007 Apr; 129(2):193-201. PMID: 17408324; PMCID: PMC3114451.
    56. Hunter KS, Lanning CJ, Chen SY, Zhang Y, Garg R, Ivy DD, Shandas R. Simulations of congenital septal defect closure and reactivity testing in patient-specific models of the pediatric pulmonary vasculature: A 3D numerical study with fluid-structure interaction. J Biomech Eng. 2006 Aug; 128(4):564-72. PMID: 16813447; PMCID: PMC4050970.
    57. Geers TL, Hunter KS. An integrated wave-effects model for an underwater explosion bubble. J Acoust Soc Am. 2002 Apr; 111(4):1584-601. PMID: 12002843.
      View in: PubMed
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