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Robert H. Friesen

TitleProfessor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-Anesthesiology
Phone720/777-6226

     Bibliographic 
     selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Clopton RG, Friesen R, Partrick D, Wilson N, Jaggers J, Ivy DD, Schwartz LI, Ing RJ. The Anesthetic Challenges of Lung Biopsy-Associated Intrathoracic Hemorrhage in a Child With Suprasystemic Pulmonary Hypertension. Semin Cardiothorac Vasc Anesth. 2016 Nov 03.
      View in: PubMed
    2. Friesen RH. Landmark papers in pediatric cardiac anesthesia: documenting the history of the specialty. Paediatr Anaesth. 2016 Nov; 26(11):1047-1052.
      View in: PubMed
    3. Cox F, Kwaks T, Brandenburg B, Koldijk MH, Klaren V, Smal B, Korse HJ, Geelen E, Tettero L, Zuijdgeest D, Stoop EJ, Saeland E, Vogels R, Friesen RH, Koudstaal W, Goudsmit J. HA Antibody-Mediated Fc?RIIIa Activity Is Both Dependent on FcR Engagement and Interactions between HA and Sialic Acids. Front Immunol. 2016; 7:399.
      View in: PubMed
    4. O'Connor S, Zhang YL, Christians U, Morrison JE, Friesen RH. Remifentanil and propofol undergo separation and layering when mixed in the same syringe for total intravenous anesthesia. Paediatr Anaesth. 2016 Jul; 26(7):703-9.
      View in: PubMed
    5. Gist KM, Kaufman J, da Cruz EM, Friesen RH, Crumback SL, Linders M, Edelstein C, Altmann C, Palmer C, Jalal D, Faubel S. A Decline in Intraoperative Renal Near-Infrared Spectroscopy Is Associated With Adverse Outcomes in Children Following Cardiac Surgery. Pediatr Crit Care Med. 2016 Apr; 17(4):342-9.
      View in: PubMed
    6. Friesen RH, Twite MD, Nichols CS, Cardwell KA, Pan Z, Darst JR, Wilson N, Fagan TE, Miyamoto SD, Ivy DD. Hemodynamic response to ketamine in children with pulmonary hypertension. Paediatr Anaesth. 2016 Jan; 26(1):102-8.
      View in: PubMed
    7. Friesen RH. Herbert Rackow and Ernest Salanitre: the emergence of pediatric anesthesia as a specialty in the United States. Paediatr Anaesth. 2015 Jul; 25(7):663-7.
      View in: PubMed
    8. Otterstrom JJ, Brandenburg B, Koldijk MH, Juraszek J, Tang C, Mashaghi S, Kwaks T, Goudsmit J, Vogels R, Friesen RH, van Oijen AM. Relating influenza virus membrane fusion kinetics to stoichiometry of neutralizing antibodies at the single-particle level. Proc Natl Acad Sci U S A. 2014 Dec 02; 111(48):E5143-8.
      View in: PubMed
    9. Friesen RH. Anesthetic drugs in congenital heart disease. Semin Cardiothorac Vasc Anesth. 2014 Dec; 18(4):363-70.
      View in: PubMed
    10. Friesen RH, Twite MD. In response. Anesth Analg. 2014 Jul; 119(1):217-8.
      View in: PubMed
    11. Twite MD, Friesen RH. The anesthetic management of children with pulmonary hypertension in the cardiac catheterization laboratory. Anesthesiol Clin. 2014 Mar; 32(1):157-73.
      View in: PubMed
    12. Friesen RH, Lee PS, Stoop EJ, Hoffman RM, Ekiert DC, Bhabha G, Yu W, Juraszek J, Koudstaal W, Jongeneelen M, Korse HJ, Ophorst C, Brinkman-van der Linden EC, Throsby M, Kwakkenbos MJ, Bakker AQ, Beaumont T, Spits H, Kwaks T, Vogels R, Ward AB, Goudsmit J, Wilson IA. A common solution to group 2 influenza virus neutralization. Proc Natl Acad Sci U S A. 2014 Jan 07; 111(1):445-50.
      View in: PubMed
    13. Brandenburg B, Koudstaal W, Goudsmit J, Klaren V, Tang C, Bujny MV, Korse HJ, Kwaks T, Otterstrom JJ, Juraszek J, van Oijen AM, Vogels R, Friesen RH. Mechanisms of hemagglutinin targeted influenza virus neutralization. PLoS One. 2013; 8(12):e80034.
      View in: PubMed
    14. Friesen RH, Nichols CS, Twite MD, Cardwell KA, Pan Z, Pietra B, Miyamoto SD, Auerbach SR, Darst JR, Ivy DD. The hemodynamic response to dexmedetomidine loading dose in children with and without pulmonary hypertension. Anesth Analg. 2013 Oct; 117(4):953-9.
      View in: PubMed
    15. Takatsuki S, Parker DK, Doran AK, Friesen RH, Ivy DD. Acute pulmonary vasodilator testing with inhaled treprostinil in children with pulmonary arterial hypertension. Pediatr Cardiol. 2013 Apr; 34(4):1006-12.
      View in: PubMed
    16. Williams GD, Friesen RH. Administration of ketamine to children with pulmonary hypertension is safe: pro-con debate: Pro Argument. Paediatr Anaesth. 2012 Nov; 22(11):1042-52.
      View in: PubMed
    17. Dreyfus C, Laursen NS, Kwaks T, Zuijdgeest D, Khayat R, Ekiert DC, Lee JH, Metlagel Z, Bujny MV, Jongeneelen M, van der Vlugt R, Lamrani M, Korse HJ, Geelen E, Sahin Ö, Sieuwerts M, Brakenhoff JP, Vogels R, Li OT, Poon LL, Peiris M, Koudstaal W, Ward AB, Wilson IA, Goudsmit J, Friesen RH. Highly conserved protective epitopes on influenza B viruses. Science. 2012 Sep 14; 337(6100):1343-8.
      View in: PubMed
    18. Cardwell K, Pan Z, Boucher R, Zuk J, Friesen RH. Screening by pulse CO-oximetry for environmental tobacco smoke exposure in preanesthetic children. Paediatr Anaesth. 2012 Sep; 22(9):859-64.
      View in: PubMed
    19. Dumond AA, da Cruz E, Almodovar MC, Friesen RH. Femoral artery catheterization in neonates and infants. Pediatr Crit Care Med. 2012 Jan; 13(1):39-41.
      View in: PubMed
    20. Ekiert DC, Friesen RH, Bhabha G, Kwaks T, Jongeneelen M, Yu W, Ophorst C, Cox F, Korse HJ, Brandenburg B, Vogels R, Brakenhoff JP, Kompier R, Koldijk MH, Cornelissen LA, Poon LL, Peiris M, Koudstaal W, Wilson IA, Goudsmit J. A highly conserved neutralizing epitope on group 2 influenza A viruses. Science. 2011 Aug 12; 333(6044):843-50.
      View in: PubMed
    21. Teng SN, Kaufman J, Czaja AS, Friesen RH, da Cruz EM. Propofol as a bridge to extubation for high-risk children with congenital cardiac disease. Cardiol Young. 2011 Feb; 21(1):46-51.
      View in: PubMed
    22. Friesen RH, Koudstaal W, Koldijk MH, Weverling GJ, Brakenhoff JP, Lenting PJ, Stittelaar KJ, Osterhaus AD, Kompier R, Goudsmit J. New class of monoclonal antibodies against severe influenza: prophylactic and therapeutic efficacy in ferrets. PLoS One. 2010 Feb 08; 5(2):e9106.
      View in: PubMed
    23. Koudstaal W, Koldijk MH, Brakenhoff JP, Cornelissen LA, Weverling GJ, Friesen RH, Goudsmit J. Pre- and postexposure use of human monoclonal antibody against H5N1 and H1N1 influenza virus in mice: viable alternative to oseltamivir. J Infect Dis. 2009 Dec 15; 200(12):1870-3.
      View in: PubMed
    24. Faulk DJ, Twite MD, Zuk J, Pan Z, Wallen B, Friesen RH. Hypnotic depth and the incidence of emergence agitation and negative postoperative behavioral changes. Paediatr Anaesth. 2010 Jan; 20(1):72-81.
      View in: PubMed
    25. Dukellis D, Zuk J, Pan Z, Morrison JE, Friesen RH. Exhaled carbon monoxide screening for environmental tobacco smoke exposure in preanesthetic children. Paediatr Anaesth. 2009 Sep; 19(9):848-53.
      View in: PubMed
    26. Ekiert DC, Bhabha G, Elsliger MA, Friesen RH, Jongeneelen M, Throsby M, Goudsmit J, Wilson IA. Antibody recognition of a highly conserved influenza virus epitope. Science. 2009 Apr 10; 324(5924):246-51.
      View in: PubMed
    27. Ghafoori AF, Twite MD, Friesen RH. Postoperative hyperglycemia is associated with mediastinitis following pediatric cardiac surgery. Paediatr Anaesth. 2008 Dec; 18(12):1202-7.
      View in: PubMed
    28. Friesen RH, Williams GD. Anesthetic management of children with pulmonary arterial hypertension. Paediatr Anaesth. 2008 Mar; 18(3):208-16.
      View in: PubMed
    29. Kaufman J, Almodovar MC, Zuk J, Friesen RH. Correlation of abdominal site near-infrared spectroscopy with gastric tonometry in infants following surgery for congenital heart disease. Pediatr Crit Care Med. 2008 Jan; 9(1):62-8.
      View in: PubMed
    30. Lupetti A, Brouwer CP, Bogaards SJ, Welling MM, de Heer E, Campa M, van Dissel JT, Friesen RH, Nibbering PH. Human lactoferrin-derived peptide's antifungal activities against disseminated Candida albicans infection. J Infect Dis. 2007 Nov 01; 196(9):1416-24.
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    31. Malviya S, Voepel-Lewis T, Tait AR, Watcha MF, Sadhasivam S, Friesen RH. Effect of age and sedative agent on the accuracy of bispectral index in detecting depth of sedation in children. Pediatrics. 2007 Sep; 120(3):e461-70.
      View in: PubMed
    32. Carmosino MJ, Friesen RH, Doran A, Ivy DD. Perioperative complications in children with pulmonary hypertension undergoing noncardiac surgery or cardiac catheterization. Anesth Analg. 2007 Mar; 104(3):521-7.
      View in: PubMed
    33. Friesen RH, Perryman KM, Weigers KR, Mitchell MB, Friesen RM. A trial of fresh autologous whole blood to treat dilutional coagulopathy following cardiopulmonary bypass in infants. Paediatr Anaesth. 2006 Apr; 16(4):429-35.
      View in: PubMed
    34. Twite MD, Zuk J, Gralla J, Friesen RH. Correlation of the Bispectral Index Monitor with the COMFORT scale in the pediatric intensive care unit. Pediatr Crit Care Med. 2005 Nov; 6(6):648-53; quiz 654.
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    35. Twite MD, Friesen RH. Pediatric sedation outside the operating room: the year in review. Curr Opin Anaesthesiol. 2005 Aug; 18(4):442-6.
      View in: PubMed
    36. Twite MD, Rashid A, Zuk J, Friesen RH. Sedation, analgesia, and neuromuscular blockade in the pediatric intensive care unit: survey of fellowship training programs. Pediatr Crit Care Med. 2004 Nov; 5(6):521-32.
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    37. Motas D, McDermott NB, VanSickle T, Friesen RH. Depth of consciousness and deep sedation attained in children as administered by nonanaesthesiologists in a children's hospital. Paediatr Anaesth. 2004 Mar; 14(3):256-60.
      View in: PubMed
    38. McDermott NB, VanSickle T, Motas D, Friesen RH. Validation of the bispectral index monitor during conscious and deep sedation in children. Anesth Analg. 2003 Jul; 97(1):39-43, table of contents.
      View in: PubMed
    39. Friesen RH, Veit AS, Archibald DJ, Campanini RS. A comparison of remifentanil and fentanyl for fast track paediatric cardiac anaesthesia. Paediatr Anaesth. 2003 Feb; 13(2):122-5.
      View in: PubMed
    40. Friesen RH, Wurl JL, Friesen RM. Duration of preoperative fast correlates with arterial blood pressure response to halothane in infants. Anesth Analg. 2002 Dec; 95(6):1572-6, table of contents.
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    41. Holth LS, Friesen R, Green C, Krahn J. A simple method for quantifying fentanyl, sufentanil, or morphine in discard syringes from anesthesia procedures. Ther Drug Monit. 2002 Oct; 24(5):665-9.
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    42. Poolman B, Blount P, Folgering JH, Friesen RH, Moe PC, van der Heide T. How do membrane proteins sense water stress? Mol Microbiol. 2002 May; 44(4):889-902.
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    43. Heuberger EH, Veenhoff LM, Duurkens RH, Friesen RH, Poolman B. Oligomeric state of membrane transport proteins analyzed with blue native electrophoresis and analytical ultracentrifugation. J Mol Biol. 2002 Apr 05; 317(4):591-600.
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    44. Wooll JO, Friesen RH, White MA, Watowich SJ, Fox RO, Lee JC, Czerwinski EW. Structural and functional linkages between subunit interfaces in mammalian pyruvate kinase. J Mol Biol. 2001 Sep 21; 312(3):525-40.
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    45. Friesen RH, Knol J, Poolman B. Quaternary structure of the lactose transport protein of Streptococcus thermophilus in the detergent-solubilized and membrane-reconstituted state. J Biol Chem. 2000 Oct 27; 275(43):33527-35.
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    46. Spooner PJ, Friesen RH, Knol J, Poolman B, Watts A. Rotational mobility and orientational stability of a transport protein in lipid membranes. Biophys J. 2000 Aug; 79(2):756-66.
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    47. Friesen RH, Wurl JL, Charlton GA. Haemodynamic depression by halothane is age-related in paediatric patients. Paediatr Anaesth. 2000; 10(3):267-72.
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    48. Fang G, Friesen R, Lanfermeijer F, Hagting A, Poolman B, Konings WN. Manipulation of activity and orientation of membrane-reconstituted di-tripeptide transport protein DtpT of Lactococcus lactis. Mol Membr Biol. 1999 Oct-Nov; 16(4):297-304.
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    49. Fekkes P, de Wit JG, Boorsma A, Friesen RH, Driessen AJ. Zinc stabilizes the SecB binding site of SecA. Biochemistry. 1999 Apr 20; 38(16):5111-6.
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    50. Friesen RH, Castellani RJ, Lee JC, Braun W. Allostery in rabbit pyruvate kinase: development of a strategy to elucidate the mechanism. Biochemistry. 1998 Nov 03; 37(44):15266-76.
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    51. Friesen RH, Chin AJ, Ledman DW, Lee JC. Interfacial communications in recombinant rabbit kidney pyruvate kinase. Biochemistry. 1998 Mar 03; 37(9):2949-60.
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    52. Morrison JE, Collier E, Friesen RH, Logan L. Preoxygenation before laryngoscopy in children: how long is enough? Paediatr Anaesth. 1998; 8(4):293-8.
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    53. Friesen RH, Campbell DN, Clarke DR, Tornabene MA. Modified ultrafiltration attenuates dilutional coagulopathy in pediatric open heart operations. Ann Thorac Surg. 1997 Dec; 64(6):1787-9.
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    54. Cheng X, Friesen RH, Lee JC. Effects of conserved residues on the regulation of rabbit muscle pyruvate kinase. J Biol Chem. 1996 Mar 15; 271(11):6313-21.
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    55. Friesen RH, Alswang M. End-tidal PCO2 monitoring via nasal cannulae in pediatric patients: accuracy and sources of error. J Clin Monit. 1996 Mar; 12(2):155-9.
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    56. Friesen RH, Alswang M. Changes in carbon dioxide tension and oxygen saturation during deep sedation for paediatric cardiac catheterization. Paediatr Anaesth. 1996; 6(1):15-20.
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    57. Friesen RH, Carpenter E, Madigan CK, Lockhart CH. Oral transmucosal fentanyl citrate for preanaesthetic medication of paediatric cardiac surgery patients. Paediatr Anaesth. 1995; 5(1):29-33.
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    58. Alswang M, Friesen RH, Bangert P. Effect of preanesthetic medication on carbon dioxide tension in children with congenital heart disease. J Cardiothorac Vasc Anesth. 1994 Aug; 8(4):415-9.
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    59. Friesen RH, Tornabene MA, Coleman SP. Blood conservation during pediatric cardiac surgery: ultrafiltration of the extracorporeal circuit volume after cardiopulmonary bypass. Anesth Analg. 1993 Oct; 77(4):702-7.
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    60. Friesen RH, Lockhart CH. Oral transmucosal fentanyl citrate for preanesthetic medication of pediatric day surgery patients with and without droperidol as a prophylactic anti-emetic. Anesthesiology. 1992 Jan; 76(1):46-51.
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    61. Morrison JE, Friesen RH. Elevated serum bromide concentrations following repeated halothane anaesthesia in a child. Can J Anaesth. 1990 Oct; 37(7):801-3.
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    62. Glenski JA, Friesen RH, Lane GA, Young S, Glascock J. Low-dose sufentanil as a supplement to halothane/N2O anaesthesia in infants and children. Can J Anaesth. 1988 Jul; 35(4):379-84.
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    63. Glenski JA, Friesen RH, Hassanein RS, Henry DB. Comparison of the hemodynamic and echocardiographic effects of sufentanil, fentanyl, isoflurane, and halothane for pediatric cardiovascular surgery. J Cardiothorac Anesth. 1988 Apr; 2(2):147-55.
      View in: PubMed
    64. Miller BR, Friesen RH. Oral atropine premedication in infants attenuates cardiovascular depression during halothane anesthesia. Anesth Analg. 1988 Feb; 67(2):180-5.
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    65. Friesen RH, Honda AT, Thieme RE. Perianesthetic intracranial hemorrhage in preterm neonates. Anesthesiology. 1987 Nov; 67(5):814-6.
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    66. Friesen RH, Honda AT, Thieme RE. Changes in anterior fontanel pressure in preterm neonates during tracheal intubation. Anesth Analg. 1987 Sep; 66(9):874-8.
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    67. Friesen RH, Morrison JE, Verbrugge JJ, Daniel WE, Aarestad NO, Burrington JD. Anesthesia for intraoperative radiation therapy in children. J Surg Oncol. 1987 Jun; 35(2):96-8.
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    68. Friesen RH, Thieme RE, Honda AT, Morrison JE. Changes in anterior fontanel pressure in preterm neonates receiving isoflurane, halothane, fentanyl, or ketamine. Anesth Analg. 1987 May; 66(5):431-4.
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    69. Friesen RH, Thieme R. Changes in anterior fontanel pressure during cardiopulmonary bypass and hypothermic circulatory arrest in infants. Anesth Analg. 1987 Jan; 66(1):94-6.
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    70. Friesen RH, Henry DB. Cardiovascular changes in preterm neonates receiving isoflurane, halothane, fentanyl, and ketamine. Anesthesiology. 1986 Feb; 64(2):238-42.
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    71. Friesen RH. Pulse oximetry during pulmonary artery surgery. Anesth Analg. 1985 Mar; 64(3):376.
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    72. Friesen RH, Lichtor JL. Cardiovascular effects of inhalation induction with isoflurane in infants. Anesth Analg. 1983 Apr; 62(4):411-4.
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    73. Friesen RH. The baroresponse and cardiovascular depression by halothane in infants. Anesthesiology. 1983 Apr; 58(4):387-8.
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    74. Friesen RH, Lichtor JL. Cardiovascular depression during halothane anesthesia in infants: study of three induction techniques. Anesth Analg. 1982 Jan; 61(1):42-5.
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    75. Friesen RH, Lichtor JL. Indirect measurement of blood pressure in neonates and infants utilizing an automatic noninvasive oscillometric monitor. Anesth Analg. 1981 Oct; 60(10):742-5.
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    76. Diaz JH, Friesen RH. Anesthetic management of congenital complete heart block in childhood. Anesth Analg. 1979 Jul-Aug; 58(4):334-6.
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    77. Friesen RH, Clement AJ. Individual responses to heparinization for extracorporeal circulation. J Thorac Cardiovasc Surg. 1976 Dec; 72(6):875-9.
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